uric acid and Urinary Calculi studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.

Research Excerpts

Excerpt	Relevance	Reference
"Uric acid excretion after 6 months of therapy in patients with urolithiasis and meta-bolic syndrome decreased from 9."	8.31	[Prevention of urolithiasis using febuxostat in patients with metabolic syndrome]. ( Babkin, PA; Paronnikov, MV; Protoshchak, VV; Sleptsov, AV, 2023)
"To disclose the link between the composition of urolithiasis, especially that of uric acid calculi, and obesity, prediabetes, type 2 diabetes mellitus, and hypertension."	7.85	The Association of Uric Acid Calculi with Obesity, Prediabetes, Type 2 Diabetes Mellitus, and Hypertension. ( Chang, CC; Chu, FY; Ho, JL; Huang, PH; Ku, PW; Lin, YN; Su, MJ; Sun, JT; Yen, TH, 2017)
"Gout is well known to be produced by increased uric acid level in blood."	7.75	Calcium oxalate stone and gout. ( Marickar, YM, 2009)
"We determined why calcium oxalate stones instead of uric acid stones form in some patients with gouty diathesis."	7.73	Physicochemical metabolic characteristics for calcium oxalate stone formation in patients with gouty diathesis. ( Moe, OW; Pak, CY; Peterson, RD; Poindexter, JR; Sakhaee, K, 2005)
"Hyperoxaluria is a major predisposing factor in calcium oxalate urolithiasis."	7.72	Dietary risk factors for hyperoxaluria in calcium oxalate stone formers. ( Ebert, D; Hesse, A; Nicolay, C; Siener, R, 2003)
"The human urinary calculi are mainly formed from calcium oxalate, magnesium ammonium phosphate hexahydrate (MAPH) and uric acid (UA) crystals."	7.72	Determination of calcium oxalate (mono- and dihydrate) in mixtures with magnesium ammonium phosphate or uric acid: the use of simultaneous thermal analysis in urinary calculi. ( El-Moselhy, TF; Kaloustian, J; Portugal, H, 2003)
"The aim of the study was to assess the influence of overweight and obesity on the risk of calcium oxalate stone formation."	7.72	The role of overweight and obesity in calcium oxalate stone formation. ( Glatz, S; Hesse, A; Nicolay, C; Siener, R, 2004)
" The elimination of electrolytes and uric acid is elevated 40 min."	7.66	Parathyroid hormone, cAMP, electrolytes and uric acid after high dose CaCl2 in patients with idiopathic stone formation. ( Dunzendorfer, U; Schmidt-Gayk, H, 1981)
"To evaluate the incidence of heterozygous cystinuria in patients with primary and recurrent calcium oxalate stone disease 24-hour urine samples from 140 patients were examined."	7.66	Heterozygous cystinuria and calcium oxalate urolithiasis. ( Blom, W; Carpentier, PJ; Huijmans, JG; Kurth, KH, 1983)
"Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function."	6.66	Renal effects of uric acid: hyperuricemia and hypouricemia. ( Jo, YI; Lee, JH; Park, JH, 2020)
"Uric acid is an end product of purine metabolism in human beings."	6.66	Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator. ( Adomako, E; Moe, OW, 2020)
"In 195 eligible patients following urinary calculi surgery, the median age was 69 (66-72) and 19 patients ultimately developed POD (9."	5.91	High ASA Physical Status and Low Serum Uric Acid to Creatinine Ratio are Independent Risk Factors for Postoperative Delirium Among Older Adults Undergoing Urinary Calculi Surgery. ( Gao, D; Li, J; Liu, J; Liu, M; Wang, J; Yu, D, 2023)
"Allopurinol has been universally successful in lowering the serum uric acid concentration and uric acid excretion to normal levels, while not significantly affecting the clearance of urate or other aspects of renal function."	5.24	The treatment of gout and disorders of uric acid metabolism with allopurinol. ( Houpt, JB; Ogryzlo, MA; Urowitz, MB; Weber, HM, 1966)
"Treatment of asymptomatic hyperuricemia is not necessary in most patients, unless perhaps they have very high levels of uric acid or are otherwise at risk of complications, such as those with a personal or strong family history of gout, urolithiasis, or uric acid nephropathy."	4.81	Asymptomatic hyperuricemia: to treat or not to treat. ( Dincer, AP; Dincer, HE; Levinson, DJ, 2002)
"A critical appraisal of the evidence commonly cited to support a link between high urate excretion and calcium oxalate (CaOx) urinary calculi is presented."	4.79	Urate and calcium oxalate stones: from repute to rhetoric to reality. ( Grover, PK; Ryall, RL, 1994)
" However, etiologic diagnosis is essential in a small number of cases: those which could benefit from effective preventive and curative measures and for which morbidity is elevated: cystinuria, hyperparathyroidism, uric acid calculi, patients at high developmental risks."	4.77	[Metabolic evaluation in urinary lithiasis. What is a reasonable level? 1: Theoretical approach]. ( Jourdan, JL; Lanson, Y, 1985)
" Uyghur pediatric patients with urolithiasis were young and the majority of stones was mixed, The main components of calculi were ammonium hydrogen urate, calcium oxalate and apatite carbonate, and there are differences in the localization of calculi between genders."	4.31	Analysis of the Components of 236 Cases of Urinary Stones in Xinjiang Uyghur Children. ( Abudureyimu, A; Aierken, Y; Kadier, A; Keyoumu, H; Li, SX; Liu, D; Ye, E, 2023)
"To assess the accuracy of low-dose dual-energy computed tomography (DECT) to differentiate uric acid from non-uric acid kidney stones in two generations of dual-source DECT with stone composition analysis as the reference standard."	4.31	Dual-energy CT kidney stone characterization-can diagnostic accuracy be achieved at low radiation dose? ( Donati, O; Euler, A; Keller, EX; Lavrek, D; Müller, D; Sartoretti, T; Wullschleger, S, 2023)
"Uric acid excretion after 6 months of therapy in patients with urolithiasis and meta-bolic syndrome decreased from 9."	4.31	[Prevention of urolithiasis using febuxostat in patients with metabolic syndrome]. ( Babkin, PA; Paronnikov, MV; Protoshchak, VV; Sleptsov, AV, 2023)
" Uric acid saturation was elevated in overweight children."	4.12	Urinary Saturations in Children with or without Renal Lithiasis. ( Areses, R; Mendia, J; Perez, M; Ubetagoyena, M, 2022)
"In addition to the controversy regarding the association of hyperuricemia with mortality, uncertainty also remains regarding the association between low serum uric acid (SUA) and mortality."	3.96	U-Shaped Association of Serum Uric Acid With All-Cause and Cause-Specific Mortality in US Adults: A Cohort Study. ( Bao, H; Cheng, X; Hu, G; Hu, L; Wang, T; Xu, BP; Zhou, W; Zhu, L, 2020)
"to clarify the influence of osteoporosis and its causative factors on excretion of calcium, uric acid and recurrence of urinary stone disease."	3.91	[Inluence of osteoporosis and its causative factors on the prevention of recurrence of urinary stone disease]. ( Amosov, AV; Amosova, MV; Demidko, LS; Demidko, YL; Enikeev, ME; Fadeev, VV; Grigoryan, VA; Kuzmicheva, GM; Rudenko, VI, 2019)
"A combination of stone size, attenuation intensity and attenuation pattern from conventional computerized tomography can distinguish uric acid stones from calcium oxalate stones with high sensitivity and specificity."	3.88	Accurately Diagnosing Uric Acid Stones from Conventional Computerized Tomography Imaging: Development and Preliminary Assessment of a Pixel Mapping Software. ( De, S; Ganesan, V; Marchini, G; Monga, M; Shkumat, N, 2018)
"To evaluate the accuracy of computed tomography (CT) texture analysis (TA) to differentiate uric acid (UA) stones from non-UA stones on unenhanced CT in patients with urinary calculi with ex vivo Fourier transform infrared spectroscopy (FTIR) as the reference standard."	3.88	Uric acid versus non-uric acid urinary stones: differentiation with single energy CT texture analysis. ( Jin, ZY; Shi, B; Sun, H; Xu, M; Xue, HD; Zhang, GM, 2018)
"To disclose the link between the composition of urolithiasis, especially that of uric acid calculi, and obesity, prediabetes, type 2 diabetes mellitus, and hypertension."	3.85	The Association of Uric Acid Calculi with Obesity, Prediabetes, Type 2 Diabetes Mellitus, and Hypertension. ( Chang, CC; Chu, FY; Ho, JL; Huang, PH; Ku, PW; Lin, YN; Su, MJ; Sun, JT; Yen, TH, 2017)
"05) in the ratio of reoccurrence of urinary calculi, age and region; calcium oxalate has the highest concentration (Uigurs: 75."	3.81	Component analysis of 251 cases of urinary calculi in Uigurs and Han in Xingjiang. ( Cheng, X; Deng, G; Ju, X; Ma, L; Meng, Q; Shui, B; Yu, Z, 2015)
"Familial renal hypouricemia (RHUC) is a hereditary disease characterized by hypouricemia, high renal fractional excretion of uric acid (FE-UA) and can be complicated by acute kidney failure and nephrolithiasis."	3.80	Recurrent exercise-induced acute renal failure in a young Pakistani man with severe renal hypouricemia and SLC2A9 compound heterozygosity. ( Cancarini, G; Chiarelli, N; Colombi, M; Gaggiotti, M; Jeannin, G; Maiorca, P; Possenti, S; Quinzani, S; Ritelli, M; Verzeletti, F, 2014)
"Experimental prospective, blinded, in vitro study using 193 urinary calculi of known composition : monohydrated calcium oxalate, mixed calcium oxalate, uric acid, and calcium carbonate, obtained from spontaneous passage or surgery."	3.80	The usefulness of densitometry in predicting the composition and fragility of urolithiasis. ( Argüelles-Salido, E; Bernardo-Villar, P; Campoy-Martínez, P; Lozano-Blasco, JM; Medina-Lopez, R; Podio-Lora, V; Subira-Rios, J; Vazquez-Albertino, R, 2014)
"Metabolic syndrome is associated with a significantly increased risk of uric acid calculi development, especially those with impaired fasting glucose and hypertriglyceridemia."	3.79	Correlation of metabolic syndrome with urinary stone composition. ( Cho, ST; Jung, SI; Kim, TH; Myung, SC, 2013)
"Renal hypouricemia (RHUC) is a heterogeneous inherited disorder characterized by impaired tubular uric acid (UA) transport with severe complications, such as acute kidney injury (AKI)."	3.79	Novel allelic variants and evidence for a prevalent mutation in URAT1 causing renal hypouricemia: biochemical, genetics and functional analysis. ( Hulkova, H; Ichida, K; Jahnova, H; Krylov, V; Kryspinova, L; Nakamura, M; Sebesta, I; Stiburkova, B, 2013)
"Renal hypouricaemia is a heterogeneous inherited disorder characterized by impaired tubular uric acid transport with severe complications, such as acute kidney injury and nephrolithiasis."	3.78	Acute kidney injury in two children caused by renal hypouricaemia type 2. ( Marinaki, AM; Sebesta, I; Stiburkova, B; Taylor, J, 2012)
"Time-of-flight secondary ion mass spectrometry was used to study four human calculi and to compare the results with those from twelve commercially available urinary calculi minerals including three organic compounds (L-cystine, uric acid and sodium urate)."	3.76	Identification of human calculi with time-of-flight secondary ion mass spectrometry. ( Carreira, OM; Ghumman, CA; Moutinho, AM; Teodoro, OM; Tolstogouzov, A; Vassilenko, V, 2010)
" In our study, calcium and uric acid abnormalities were the most common, and vesicoureteral reflux seemed to be the most common urological abnormality which led to urinary stasis and calculus formation."	3.76	Metabolic factors associated with urinary calculi in children. ( Alamdaran, SA; Naseri, M; Varasteh, AR, 2010)
"Gout is well known to be produced by increased uric acid level in blood."	3.75	Calcium oxalate stone and gout. ( Marickar, YM, 2009)
"We determined why calcium oxalate stones instead of uric acid stones form in some patients with gouty diathesis."	3.73	Physicochemical metabolic characteristics for calcium oxalate stone formation in patients with gouty diathesis. ( Moe, OW; Pak, CY; Peterson, RD; Poindexter, JR; Sakhaee, K, 2005)
" Partial HPRT deficiency usually causes hyperuricemia, precocious gout, and uric acid nephrolithiasis."	3.73	Eighteen-year follow-up of a patient with partial hypoxanthine phosphoribosyltransferase deficiency and a new mutation. ( Gregoric, A; Kokalj Vokac, N; Rabelink, GM; Varda, NM; Zagradisnik, B, 2005)
"Hyperoxaluria is a major predisposing factor in calcium oxalate urolithiasis."	3.72	Dietary risk factors for hyperoxaluria in calcium oxalate stone formers. ( Ebert, D; Hesse, A; Nicolay, C; Siener, R, 2003)
"To test the hypothesis that stone-forming patients with type II diabetes (DM-II) have a high prevalence of uric acid (UA) stones and present with some of the biochemical features of gouty diathesis (GD)."	3.72	Biochemical profile of stone-forming patients with diabetes mellitus. ( Ekeruo, W; Moe, O; Pak, CY; Peterson, RD; Pietrow, P; Poindexter, JR; Preminger, GM; Sakhaee, K, 2003)
"The human urinary calculi are mainly formed from calcium oxalate, magnesium ammonium phosphate hexahydrate (MAPH) and uric acid (UA) crystals."	3.72	Determination of calcium oxalate (mono- and dihydrate) in mixtures with magnesium ammonium phosphate or uric acid: the use of simultaneous thermal analysis in urinary calculi. ( El-Moselhy, TF; Kaloustian, J; Portugal, H, 2003)
"The aim of the study was to assess the influence of overweight and obesity on the risk of calcium oxalate stone formation."	3.72	The role of overweight and obesity in calcium oxalate stone formation. ( Glatz, S; Hesse, A; Nicolay, C; Siener, R, 2004)
"To determine whether the biochemical presentation and urinary physicochemical environment of patients with hyperuricosuria presenting with calcium stones (hyperuricosuric calcium urolithiasis [HUCU]) differs from those of patients with gouty diathesis (GD) or idiopathic uric acid urolithiasis."	3.71	Biochemical distinction between hyperuricosuric calcium urolithiasis and gouty diathesis. ( Koska, J; Pak, CY; Peterson, RD; Poindexter, JR; Sakhaee, K, 2002)
" Urinary excretion rates of calcium, sodium, chloride, potassium, urinary calcium/creatinine index, the fractional excretion of sodium, potassium and uric acid, the creatinine clearance and serum values of creatinine, urea, uric acid, electrolytes, total proteins, parathormone (intact molecule), plasma renin activity, aldosterone, glucose, and insulin (fasting and after an oral glucose load) were performed in every patient and control subject."	3.69	Urinary calcium excretion in treated and untreated essential hypertension. ( Navarro-Antolin, J; Orte, L; Ortuño, J; Quereda, C; Sabater, J; Villafruela, JJ, 1996)
"Xanthine calculi were found in a 7-month-old male Cavalier King Charles spaniel with urethral obstruction and renal insufficiency."	3.69	Xanthinuria in a family of Cavalier King Charles spaniels. ( Nickel, RF; Reijngoud, DJ; van Dijk, TH; van Zuilen, CD, 1997)
" Acromegaly is associated with metabolic disturbances of calcium and phosphorus which can also contribute to renal lithogenesis."	3.68	Metabolic factors for urolithiasis in acromegalic patients. ( Ajzen, H; Czepielewski, MA; Heilberg, IP; Ramos, OL; Schor, N, 1991)
"In an analysis, by both crystallographic and microbiological methods, of 50 urinary calculi recently removed by surgical operation, 33 proved to be of metabolic origin (mostly calcium oxalate and some uric acid or urate) and 17 of 'infective' origin (struvite, apatite or a mixture of the two)."	3.67	Bacteriological and crystallographical analysis of urinary calculi: aid to patient management. ( Brumfitt, W; Hamilton-Miller, JM; Hopewell, JP; Osborn, RS; Rosenstein, I, 1984)
"Calcium oxalate is the most important constituent of urinary calculi and the excretion pattern of calcium and oxalate is not consistent with stone formation."	3.67	Changes in urinary composition of calcium oxalate stone formers. ( Rahman, B; Rahman, MA, 1986)
" The elimination of electrolytes and uric acid is elevated 40 min."	3.66	Parathyroid hormone, cAMP, electrolytes and uric acid after high dose CaCl2 in patients with idiopathic stone formation. ( Dunzendorfer, U; Schmidt-Gayk, H, 1981)
" The role of uric acid in cystinuria is discussed."	3.66	X-ray diffractometric analysis of L-cystine stones in 12 patients. ( Babionitakis, A; Dimopoulos, C; Kallistratos, G; Karayiannis, A; Kyriakidis, A; Markopoulos, T; Sideris, S; Stokidis, D, 1983)
"To evaluate the incidence of heterozygous cystinuria in patients with primary and recurrent calcium oxalate stone disease 24-hour urine samples from 140 patients were examined."	3.66	Heterozygous cystinuria and calcium oxalate urolithiasis. ( Blom, W; Carpentier, PJ; Huijmans, JG; Kurth, KH, 1983)
"We report on 8 azotemic patients with anuria or progressive oliguria owing to bilateral uric acid lithiasis."	3.66	Management of the choked ureter in obstructive renal failure due to uric acid lithiasis. ( Ansari, ER; Husain, I; Kazim, E, 1982)
"Human uric acid acid renal stones are easily distinguished from other urinary calculi by their globular or spherical shape, their colour and their hardness."	3.66	Studies on the morphology of human uric acid stones. ( Dobler, M; Gordon, T; Kedar, S; Kleeberg, J, 1981)
"Fifty-seven per cent of Urinary Calculi in the Sudan contain Uric Acid, 20 per cent in the pure form and 37 per cent mixed with other constituents mainly calcium oxalate."	3.65	Uric acid lithiasis in the Sudan. ( Beleil, O; Ibrahim, A; Zein, M, 1977)
"Overweight has been suggested to increase the risk of kidney stone formation."	3.11	Effect of Two Different Dietary Weight Loss Strategies on Risk Factors for Urinary Stone Formation and Cardiometabolic Risk Profile in Overweight Women. ( Alteheld, B; Bitterlich, N; Ernsten, C; Metzner, C; Siener, R, 2022)
"The prevalence of urolithiasis is steadily increasing worldwide in both genders."	2.82	[Urolithiasis-Therapy and recurrence prevention taking into account gender-specific aspects]. ( Neisius, A; Siener, R; Strohmaier, WL, 2022)
"Therefore, the components of urinary stones were closely related to the components of urinary crystallites."	2.78	Property changes of urinary nanocrystallites and urine of uric acid stone formers after taking potassium citrate. ( Ouyang, JM; Shang, YF; Xue, JF; Zhang, GN, 2013)
"About 10-15% of all urinary stones are composed of uric acid."	2.71	The effect of a vegetarian and different omnivorous diets on urinary risk factors for uric acid stone formation. ( Hesse, A; Siener, R, 2003)
"When calcium citrate was combined with potassium citrate, urinary calcium remained high, urinary citrate increased even further and urinary oxalate remained reduced from the calcium citrate alone, thereby marginally decreasing the urinary saturation of calcium oxalate."	2.71	Stone forming risk of calcium citrate supplementation in healthy postmenopausal women. ( Griffith, CS; Pak, CY; Poindexter, JR; Sakhaee, K, 2004)
"Indapamide is an antihypertensive agent similar to thiazides, but with some different effects."	2.71	Effect of indapamide on urinary calcium excretion in patients with and without urinary stone disease. ( Algun, E; Can, S; Ceylan, K; Dogan, E; Erkoc, R; Gonulalan, H; Sayarlioglu, H; Topal, C; Yilmaz, Y, 2005)
"Calcium oxalate SS was similar between children and adults, and urine pH was the major cause of differences seen in the calcium phosphate and uric acid SS indices."	2.71	Results of a prospective trial to compare normal urine supersaturation in children and adults. ( Asplin, J; Defoor, W; Jackson, C; Jackson, E; Minevich, E; Reddy, P; Sheldon, C, 2005)
"Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function."	2.66	Renal effects of uric acid: hyperuricemia and hypouricemia. ( Jo, YI; Lee, JH; Park, JH, 2020)
"Uric acid is an end product of purine metabolism in human beings."	2.66	Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator. ( Adomako, E; Moe, OW, 2020)
"Urolithiasis is a widespread chronic disease; its prevalence has been steadily increasing over the past 50 years."	2.58	[Urate urolithiasis: pathogenesis and possibilities of conservative therapy]. ( Frolova, EA; Rapoport, LM; Saenko, VS; Tsarichenko, DG, 2018)
"The incidence and prevalence of urinary calculi is increasing globally."	2.53	National Profiles of Urinary Calculi: a Comparison Between Developing and Developed Worlds. ( Alatab, S; Buchholz, N; El Howairis, Mel F; Mashhadi, R; Najafi, I; Pourmand, G; Pourmand, MR; Pourmand, N, 2016)
"Hyperuricemia is a specific risk factor for cardiovascular morbidity and mortality."	2.47	[Hyperuricemia and uro-nephrological disorders]. ( Hurtes, X; Meria, P, 2011)
"The urolithiasis is a growing disease because of the changes in dietary habits and in he general life style."	2.45	Metaphylaxis of urolithiasis. ( Menditto, VG; Milanese, G; Muzzonigro, G, 2009)
"Uric acid stone disease has a rich and fascinating medical history and probably is the oldest known stone disease."	2.42	Uric acid stone disease. ( Moran, ME, 2003)
"As long as urinary stones continue to afflict humans, chemolysis is likely to retain a limited but important role in their management."	2.41	Chemolysis of urinary calculi. ( Bernardo, NO; Smith, AD, 2000)
"Hematuria is one of the most common urinary abnormalities found in children."	2.39	Hematuria associated with hypercalciuria and hyperuricosuria: a practical approach. ( Stapleton, FB, 1994)
"Uric acid is a weak acid that ionizes with a Pka at pH 5."	2.39	Uric acid nephrolithiasis. ( Halabe, A; Sperling, O, 1994)
"Uric acid is one of the composition of urinary stones itself, but it has an activity of calcium oxalate stone formation."	2.39	[Hyperuricosuria and urolithiasis]. ( Koide, T, 1996)
"A previous study of urinary stones by a combined electron microscopy demonstrated the potential of scanning electron microscopy and X-ray analysis as an analytic tool for urinary stones."	2.37	X-ray microanalysis of urinary stones, a comparison with other methods. ( Alpaugh, HB; Johnson, FB; Kim, KM, 1985)
"Fifty-two children with urinary calculi seen between 1975 and 1986 were reviewed."	2.37	Urolithiasis in Jordanian children. A report of 52 cases. ( Abu Khadra, AL; Baghdadi, FM; Dajani, AM, 1988)
"Urinary stones are much more common in subjects with intestinal diseases than in the general population."	2.36	[Urinary lithiasis secondary to intestinal diseases]. ( Calmus, Y; Gendre, JP; Mignon, F, 1983)
"In 195 eligible patients following urinary calculi surgery, the median age was 69 (66-72) and 19 patients ultimately developed POD (9."	1.91	High ASA Physical Status and Low Serum Uric Acid to Creatinine Ratio are Independent Risk Factors for Postoperative Delirium Among Older Adults Undergoing Urinary Calculi Surgery. ( Gao, D; Li, J; Liu, J; Liu, M; Wang, J; Yu, D, 2023)
"The effect of obstructive sleep apnea (OSA) on 24-h urine parameters and resultant kidney stone risk is unknown."	1.91	Association between obstructive sleep apnea and 24-h urine chemistry risk factors for urinary stone disease. ( Hsi, RS; Miller, NL; Stone, BV; Sui, W; Tallman, JE, 2023)
"Fifteen urinary stones were chemically analyzed, and their chemical compositions were considered a reference standard with which we compared the uric acid (UA) and non-UA compositions determined using DECT."	1.91	Optimal dual-energy computed tomography scan parameters to detect small-sized urinary stones and their composition. ( Choi, HJ; Jung, JW; Pak, S; Shin, JB; Yang, H; Yoon, BI, 2023)
"Uric acid stones were associated with medical conditions such as diabetes, hypertension, ischemic heart disease, and obesity (28."	1.91	The relationship between patients' kidney stone type and demographics in Israel: analysis of 10 K patients. ( Cohen, S; Dekel, Y; Friefeld, Y; Klein, I; Pilosov Solomon, I; Saliba, W; Tor, R; Zreik, R, 2023)
"While most urinary stones are managed with interventional therapy, uric acid (UA) stones can be dissolved by oral chemolysis without invasive procedures."	1.91	Pure uric acid stone prediction model using the variant coefficient of stone density measured by thresholding 3D segmentation-based methods: A multicenter study. ( Jung, W; Kim, BS; Lee, J; Song, BI, 2023)
"Calcium oxalate uroliths were the most accurately measured and struvite were the least accurately measured when compared with the gross measurement."	1.91	The most common types of uroliths larger than 1 mm are readily visible and accurately measured in an in vitro setting mimicking the canine abdomen using digital radiography. ( Auger, M; Cline, K; de Swarte, M; DeBow, P; Fazio, C; Hespel, AM; Lamb, D; Lulich, J; Zhu, X, 2023)
"Urolithiasis is a major public health issue due to its increasing prevalence."	1.91	Epidemiology and composition of upper urinary tract lithiasis in Senegalese population: a multicenter retrospective study. ( Dominique, D; Lamine, N; Modou, N; Mohamed, D; Mohamed, SS; Motoula Latou, L; Racine, K, 2023)
"Herein, selected human bladder stones have been deeply characterized for clinical purposes and environmental biomonitoring, focusing on the importance to evaluate the concentration and distribution of undesired trace elements by means of microscopic techniques in the place of conventional wet chemical analyses."	1.72	May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications? ( Carafa, A; Di Meo, MC; Gatta, GD; Germinario, C; Grifa, C; Izzo, F; Langella, A; Lotrecchiano, G; Mercurio, M; Saldutto, P; Salzano, L; Varricchio, E, 2022)
"Adenovirus gastroenteritis is a common cause of diarrhea and vomiting in infants, resulting in prerenal acute kidney injury (AKI)."	1.72	Acute kidney injury due to ammonium acid urate stones in a patient with adenovirus gastroenteritis: a case report. ( Ban, H; Hattori, M; Hirai, K; Miura, K; Tomoeda, R, 2022)
"Cardio-metabolic diseases and Parkinson's disease were more frequent in men with hypouricaemia than those without hypouricaemia."	1.72	Temporal trends in the prevalence and characteristics of hypouricaemia: a descriptive study of medical check-up and administrative claims data. ( Kawakami, K; Koto, R; Kuwabara, M; Sato, I; Seki, T, 2022)
"Surface and section images of 123 urinary calculi (109 ex vivo and 14 in vivo stones) were acquired using ureteroscopes."	1.72	Evaluation and understanding of automated urinary stone recognition methods. ( Daudon, M; Daul, C; El Beze, J; Eschwège, P; Hubert, J; Mazeaud, C; Ochoa-Ruiz, G, 2022)
"22) and their concentrations within the urinary stones."	1.72	Micro-elemental analysis and characterization of major heavy metals and trace elements in the urinary stones collected from patients living in diverse geographical regions. ( Abdel-Gawad, M; Alhayek, S; Ali-El-Dein, B; Alkohlany, K; Alsaigh, N; Buchholz, N; Elsobky, E; Kamphuis, G; Knoll, T; Kura, M; Mehta, S; Monga, M, 2022)
"A total of 45,783 urinary stones submitted from 32,512 men and 13,271 women between January 2007 and December 2020 were analyzed by infrared spectroscopy."	1.72	Urinary stone composition in Germany: results from 45,783 stone analyses. ( Herwig, H; Hesse, A; Lossin, P; Rüdy, J; Schaefer, RM; Siener, R, 2022)
"The predominant components of the calculi were cystine (20), struvite (15), calcium oxalate (8), and urate (7)."	1.72	Computed tomographic assessment of retrograde urohydropropulsion in male dogs and prediction of stone composition using Hounsfield unit in dogs and cats. ( Bedu, AS; Bruwier, A; Gatel, L; Godart, B; Leperlier, D, 2022)
"Pure uric acid composition was found in 16% of stones."	1.62	[Chemical composition analysis of 649 urinary stones]. ( López, C; Navarro, P; Salvadó, JA; Sánchez, R; Troncoso, MP, 2021)
"Thirty-two urinary stones embedded in gelatin were mounted on a Styrofoam disk and placed into a water-filled phantom."	1.62	Low-dose dual-energy CT for stone characterization: a systematic comparison of two generations of split-filter single-source and dual-source dual-energy CT. ( Alkadhi, H; Eberhard, M; Euler, A; Krauss, B; Müller, D; Nakhostin, D; Sartoretti, T, 2021)
"Owing to the importance of urinary stones as one of the biominerals in the human body, it is necessary to investigate their chemical composition and mineralogy."	1.62	Mineralogy, geochemistry, ( Aghajari, S; Nazarpour, A; Rozbahani, MM; Sabzalipour, S, 2021)
"Of 84 patients with 144 urinary stones, 10 (11."	1.51	Diagnostic accuracy of third-generation dual-source dual-energy CT: a prospective trial and protocol for clinical implementation. ( Isbarn, H; Neisius, A; Nestler, K; Nestler, T; Netsch, C; Ruf, C; Schmelz, HU; Waldeck, S, 2019)
"Calcium oxalate stones were 60%, uric acid 18."	1.51	Analysis of chemical composition of urinary calculi from Northern border area of Saudi Arabia. ( Hussain, MA; Malik, NA, 2019)
"Eighty-seven human urinary stones with pure mineral composition were placed in four anthropomorphic water phantoms (35-50 cm lateral dimension) and scanned on a PCD-CT system at 100, 120, and 140 kV."	1.48	Characterization of Urinary Stone Composition by Use of Whole-body, Photon-counting Detector CT. ( Ferrero, A; Gutjahr, R; Halaweish, AF; Leng, S; McCollough, CH, 2018)
"Fifty-seven extracted urinary calculi were placed in a cylindrical phantom in a water bath and scanned on a SDCT scanner (IQon, Philips Healthcare) and second- and third-generation dsDECT scanners (Somatom Flash and Force, Siemens Healthcare) under matched scan parameters."	1.48	Dual-layer spectral detector CT: non-inferiority assessment compared to dual-source dual-energy CT in discriminating uric acid from non-uric acid renal stones ex vivo. ( Abbara, S; Ananthakrishnan, L; Antonelli, JA; Duan, X; Fielding, JR; Goerne, H; Kolitz, EM; Lenkinski, RE; Lewis, MA; Leyendecker, JR; Pearle, MS; Xi, Y, 2018)
"Uric acid stone was more prevalent in group >60 years (66."	1.48	Kidney Stone Composition in Third-World Areas: What Kashgar Tells Us? ( Batuer, A; Chen, D; Jiang, C; Li, Z; Liu, Y; Luo, J; Shataer, A; Tuerxun, A; Zhou, Y, 2018)
"To analyze types of urinary calculi and patients' clinical characteristics, and to explore the strategies for prevention and treatment of urinary calculi."	1.48	[Types for 1 849 patients with urinary calculi and patients' clinical characteristics]. ( Chen, B; Jiang, Z; Liu, D; Tan, J; Wang, C; Xue, J, 2018)
"It is a fact that recurrence of urinary stones is a common medical problem."	1.46	Easy-to-use equations for the estimation of urine relative saturation in the assessment of risk of recurrence in urinary stones formers. ( Ouimet, D; Plante, G; Robitaille, R, 2017)
"To explore underlying mechanism of urinary stones formation, the composition and microstructure of urinary stones were analyzed systematically with a large sample study from China."	1.46	The systematic classification of urinary stones combine-using FTIR and SEM-EDAX. ( Li, Q; Luo, XB; Ma, RH; Zhong, HQ, 2017)
"Although urolithiasis has been reported clinically in reptiles, this report presents the first case of a cystic calculus in a laboratory-housed green anole."	1.46	Cystic Calculus in a Laboratory-housed Green Anole ( ( Birke, LL; Cespedes, AM; Lailvaux, SP; Schachner, ER, 2017)
"Prevalence of urinary calculi in children has been increasing in the past years."	1.46	Fourier Transform Infrared Analysis of Urinary Calculi and Metabolic Studies in a Group of Sicilian Children. ( D'Alessandro, MM; Gennaro, G; Maringhini, S; Tralongo, P, 2017)
"Calcium oxalate (CaOx) was the main stone composition in both Uyghur (35."	1.46	Difference in urinary stone composition between Uyghur and Han children with urolithiasis. ( Chen, K; Lan, C; Liang, Y; Liu, Y; Ou, L; Tiselius, HG; Tusong, H; Wu, W; Yasheng, A; Zeng, G, 2017)
"Urinary stones were collected mostly in the nephrology service and urology service at the Hassan II Hospital in Fez."	1.43	[Epidemiological study on urinary stones in the region of Fez and the risk of recurrence]. ( Arrayhani, M; Chaqroune, A; Chouhani, BA; Dami, F; El Ammari, J; El Habbani, R; Lahrichi, A; Sqalli Houssaini, T, 2016)
"To better understand the basis of urinary calculi formation, we studied the composition, microstructure, and element analysis of different types of urinary calculi."	1.43	Composition, microstructure and element study of urinary calculi. ( Wang, D; Zhang, B; Zhang, M; Zhang, X, 2016)
"Mineralogical composition of 100 urinary stones from urolithiasis patients living in Ivanovo region was examined."	1.43	[Quantitative mineralogical analysis and structure of urinary stones in patients living in Ivanovo region]. ( Airapetyan, AO; Gruzdev, SI; Gusakova, SV; Kustov, AV; Moryganov, MA; Smirnov, PR; Strelnikov, AI; Toms, SR, 2016)
"Multi-components of urinary calculi such as calcium oxalate, hydroxyl apatite, struvite and uric acid have been studied."	1.42	FT-IR spectroscopic, thermal analysis of human urinary stones and their characterization. ( Raja, A; Selvaraju, R; Thiruppathi, G, 2015)
"In view of the high incidence rate of urinary stones in the south and southwest of Iran, this paper investigates trace elements content including heavy metals in 39 urinary stones, collected from patients in Fars province, Iran."	1.42	Trace elements in urinary stones: a preliminary investigation in Fars province, Iran. ( Irani, D; Keshavarzi, B; Moore, F; Salari, M; Yavarashayeri, N; Zarasvandi, A, 2015)
"Uric acid (UA) serves as an antioxidant in vascular endothelial cells."	1.42	Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia. ( Hamada, T; Higashi, Y; Hisatome, I; Ichida, K; Kato, M; Kuwabara, M; Maharani, N; Ninomiya, H; Niwa, K; Ogino, K; Sugihara, S; Yamamoto, K, 2015)
"Rotavirus gastroenteritis is severe and often results in dehydration and pre-renal azotemia."	1.42	Clinical characteristics of rotavirus gastroenteritis with urinary crystals. ( Ashida, A; Matsumura, H; Nakakura, H; Shirasu, A; Tamai, H, 2015)
"Calcium oxalate stone was the most common component at 82."	1.40	Urinary stone analysis on 12,846 patients: a report from a single center in China. ( Li, S; Liang, Y; Ou, L; Wan, S; Wu, W; Yang, B; Zeng, G, 2014)
"The analysis of urinary stones is mandatory for the best management of the disease after the stone passage in order to prevent further stone episodes."	1.40	Taking advantage of hyperspectral imaging classification of urinary stones against conventional infrared spectroscopy. ( Blanco, F; Bonifazi, G; López-Mesas, M; Lumbreras, F; Serranti, S; Serrat, J; Siener, R; Valiente, M, 2014)
"Spectroscopic studies of urinary stones and corresponding sediments from 76 patients suffering from renal stone disease reveal that in 73% of cases such correlation exists."	1.39	Combined studies of chemical composition of urine sediments and kidney stones by means of infrared microspectroscopy. ( Hendrixson, V; Jablonskienė, V; Jankevičius, F; Kučinskienė, ZA; Pučetaitė, M; Šablinskas, V; Tamošaitytė, S; Tyla, R; Želvys, A, 2013)
"Moreover, urinary calculi can also be used for assessing exposure of humans to minor and trace elements in addition to other biological matrices, for example, blood, urine, or hair."	1.39	Association of minor and trace elements with mineralogical constituents of urinary stones: a hard nut to crack in existing studies of urolithiasis. ( Benová, D; Červenka, R; Kuta, J; Machát, J; Martinec, P; Zeman, J, 2013)
"Urolithiasis is a common disease with increasing incidence and prevalence world-wide, probably more common in industrialized countries."	1.39	Twenty-four-hour urine constituents in stone formers: a study from the northeast part of Peninsular Malaysia. ( Gohar, MN; Hussein, NS; Kamaliah, MD; Norakmal, AW; Sadiq, SM, 2013)
"In the present study the human urinary stones were observed in their different chemical compositions of calcium oxalate monohydrate, calcium oxalate dihydrate, calcium phosphate, struvite (magnesium ammonium phosphate), uric acid, cystine, oxammite (ammonium oxalate monohydrate), natroxalate (sodium oxalate), glushinkite (magnesium oxalate dihydrate) and moolooite (copper oxalate) were analyzed using Fourier Transform-Raman (FT-Raman) spectroscopy."	1.39	Chemical composition and binary mixture of human urinary stones using FT-Raman spectroscopy method. ( Raja, A; Selvaraju, R; Thiruppathi, G, 2013)
"Exercise-induced acute renal failure [exercise-induced acute kidney injury (EI-AKI)] is defined as AKI due to heavy anaerobic exercise."	1.39	Molecular background of urate transporter genes in patients with exercise-induced acute kidney injury. ( Iijima, K; Ishimori, S; Kaito, H; Nakanishi, K; Nozu, K; Shima, Y; Yoshikawa, N, 2013)
"The uric acid crystals were re-crystallized from a suspension of uric acid powder, and the micro-crystals were prepared to be floating in the solution."	1.39	Magnetic rotations of uric acid crystals and uratic crystals by static magnetic fields of up to 500 mT. ( Iwasaka, M; Mizukawa, Y; Takeuchi, Y, 2013)
"A total of 126 patients with bilateral urinary calculi were recruited to undergo percutaneous nephrolithotomy or ureteroscopes lithotripsy."	1.39	[Composition analyses of bilateral urinary tract calculis]. ( He, M; Li, WG; Pang, X; Wang, J; Yu, XX; Zhou, DQ, 2013)
"Uric acid stones were found in only 14."	1.39	Urinary stone composition in Israel: current status and variation with age and sex--a bicenter study. ( Abdin, T; Duvdevani, M; Golan, S; Lifshitz, D; Livne, PM; Pode, D; Usman, KD, 2013)
"In 104 patients with urinary calculi targeted dual-energy imaging within one breath-hold was added."	1.38	Targeted dual-energy single-source CT for characterisation of urinary calculi: experimental and clinical experience. ( Dobritz, M; Eiber, M; Frimberger, M; Holzapfel, K; Huber, A; Rummeny, EJ; Schneider, H; Straub, M, 2012)
"The analysis of urinary stones is used for the diagnosis of the etiology of an episode of nephrolithiasis."	1.38	Development of a method for the quantitative analysis of urinary stones, formed by a mixture of two components, using infrared spectroscopy. ( Arroyo Fernández, M; García Alvarez, JL; Torrejón Martínez, MJ, 2012)
"Quantitative analyses of urinary stones show that calcium oxalate monohydrate (40%), apatite (30%), magnesium ammonium phosphate (23%) and uric acid (7%) are present in all the urinary stone samples."	1.38	FT-IR spectral studies on certain human urinary stones in the patients of rural area. ( Raja, A; Selvaraju, R; Thiruppathi, G, 2012)
"Calcium oxalate monohydrate was the most frequent stone component, even though its frequency decreased with age (59."	1.38	Changes in urinary stone composition in the Tunisian population: a retrospective study of 1,301 cases. ( Alaya, A; Belgith, M; Jouini, R; Najjar, MF; Nouri, A; Saad, H, 2012)
"The quantitative estimation of human urinary stones suitable for the single calibration curve was performed."	1.38	FT-Raman spectral analysis of human urinary stones. ( Raja, A; Selvaraju, R; Thiruppathi, G, 2012)
"A series of 5,248 urinary stones was analyzed by Fourier transform infrared spectroscopy between 1999 and 2008."	1.37	Infrared spectroscopic analysis of 5,248 urinary stones from Chinese patients presenting with the first stone episode. ( Cong, X; He, L; Lu, J; Shen, L; Sun, X; Zhu, H, 2011)
"Urinary stones were classified as UA-containing or non-UA-containing based on CT number measurements and DE software results."	1.36	In vivo identification of uric acid stones with dual-energy CT: diagnostic performance evaluation in patients. ( Alkadhi, H; Chuck, N; Kozomara, M; Leschka, S; Müntener, M; Scheffel, H; Stolzmann, P, 2010)
"However the exact aetiology of urinary stones still remains elusive."	1.36	Increased urinary uric acid excretion: a finding in Indian stone formers. ( Karan, SC; Kotwal, A; Sinha, T, 2010)
"The Thulium fiber laser has recently been tested as a potential alternative to the Holmium:YAG laser for lithotripsy."	1.36	Thulium fiber laser lithotripsy using tapered fibers. ( Blackmon, RL; Fried, NM; Irby, PB, 2010)
"Urate urolithiasis was more frequent in younger cats (mean age 6."	1.36	Feline urate urolithiasis. ( Appel, SL; Houston, DM; Moore, AE; Weese, JS, 2010)
"Calcium oxalate was present in nearly all stones, and the majority of renal calcium stones contains mixtures of calcium oxalate and calcium phosphates in addition some contains uric acid or magnesium ammonium phosphate."	1.36	The composition and quantitative analysis of urinary calculi in patients with renal calculi. ( Bhutey, AK; Jawalekar, S; Surve, VT, 2010)
"Forty urinary stones of 16 different compositions in two sizes (or=5 mm) were examined in an ex vivo model."	1.35	Dual-energy computed tomography for the differentiation of uric acid stones: ex vivo performance evaluation. ( Alkadhi, H; Frauenfelder, T; Leschka, S; Marincek, B; Rentsch, K; Scheffel, H; Schertler, T; Stolzmann, P; Sulser, T, 2008)
"In this work 85337 urinary stones were analysed by X-ray diffraction in regard of their qualitative and quantitative composition."	1.35	[Results of the evaluation of 85,337 urinary stone analyses]. ( Bastian, HP; Bastian, PJ; Euler, H; Lörken, M; Lümmen, G, 2008)
"Crystallographic analysis of complex urinary stones with the aid of x-ray diffraction, in combination with a Rietveld structure refinement, is the method of first choice for qualitative and quantitative phase analysis."	1.35	[Qualitative and quantitative analysis of urolithiasis with the Rietveld method (x-ray diffraction)]. ( Bastian, HP; Bastian, PJ; Euler, H; Lümmen, G, 2008)
"A series of 426 urinary stones, 33 from the lower (LUT) and 393 from the upper urinary tract (UUT) of adults, were analyzed for their chemical composition using infrared spectroscopy."	1.35	Chemical components of urinary stones according to age and sex of adult patients. ( Bovornpadungkitti, S; Chotikawanich, E; Pachitrat, K; Prasongwatana, V; Sriboonlue, P; Suwanatrai, S, 2008)
"The composition of urinary stones in children depends on socioeconomic conditions, geography and dietary habits."	1.35	Metabolic stone composition in Egyptian children. ( AbdelHamid, AZ; AbdelRahman, S; Aggour, A; Morsi, A; Ziada, AM, 2009)
"Uric acid urolithiasis was predominant in men in this study."	1.35	Local factors compared with systemic factors in the formation of bladder uric acid stones. ( Chou, YH; Huang, CH; Huang, SP; Li, CC; Li, WM; Liu, CC; Wu, WJ, 2009)
"We studied 98 patients with Crohn's disease: 39 with urolithiasis and 59 without urolithiasis."	1.35	Clinical evaluation of urolithiasis in Crohn's disease. ( Hara, H; Ishii, G; Ishii, N; Kato, M; Nakajima, K; Tanaka, N, 2009)
"Uric acid calculi were found in 53 cases (18."	1.35	[Percentage of uric acid calculus and its metabolic character in Dongjiang River valley]. ( An, G; Chong, HH, 2009)
"Uric acid was more in the inner layers of mixed stones than the surface."	1.35	Ultrastructural study of laminated urinary stone. ( Fazil Marickar, YM; Koshy, P; Varma, L, 2009)
"A total of 250 urinary stones of different compositions were collected from stone clinic, photographed, observed under an optical microscope, and optical photographs were taken at different angles."	1.35	Optical microscopy versus scanning electron microscopy in urolithiasis. ( Koshy, P; Lekshmi, PR; Marickar, YM; Varma, L, 2009)
"To identify recurrence of uroliths in cats for which uroliths were submitted for analysis at the Minnesota Urolith Center in 1998, the facility's database was searched for urolith resubmissions from the same cats between 1998 and 2003."	1.35	Rate and frequency of recurrence of uroliths after an initial ammonium urate, calcium oxalate, or struvite urolith in cats. ( Albasan, H; Koehler, LA; Lekcharoensuk, C; Lulich, JP; Osborne, CA; Swanson, LL; Ulrich, LK, 2009)
"Some studies have suggested that HUs of urinary calculi on noncontrast computed tomography may predict the stone-free rate after ESWL."	1.33	Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. ( Armenakas, NA; Bruno, JJ; Fracchia, JA; Panagopoulos, G; Pareek, G, 2005)
"For this study, 25 samples of urinary stones were chosen from different provinces in Iraq as representative sampling localities."	1.33	Mineralogical composition of the urinary stones from different provinces in Iraq. ( Afaj, AH; Sultan, MA, 2005)
"Hyperuricosuria, hyperoxaluria and a low urinary volume did not influence the risk for active stone formation."	1.33	Risk factors determining active urinary stone formation in patients with urolithiasis. ( Netelenbos, JC; ter Wee, PM; Zwijnenburg, PJ, 2005)
"In our laboratory more than 100,000 urinary calculi have been analysed since 1972."	1.33	Uric acid monohydrate--a new urinary calculus phase. ( Jancke, H; Kraus, W; Patzelt, C; Reck, G; Schubert, G, 2005)
"Uric acid crystalluria was twice as frequent in women than in men (66% vs 33."	1.33	[Study of crystalluria in diabetic patients]. ( Daudon, M; Jabrane, J; Mbarki, M; Oussama, A, 2005)
" Daily PRAL was calculated considering the mineral and protein composition of foods, the mean intestinal absorption rate for each nutrient and the metabolism of sulfur-containing amino acids."	1.33	Effect of potential renal acid load of foods on urinary citrate excretion in calcium renal stone formers. ( Lizzano, R; Marchesotti, F; Trinchieri, A; Zanetti, G, 2006)
"Two-thirds of the organic matrix in urinary stones consists of proteins."	1.33	Protein profiling of organic stone matrix and urine from dogs with urolithiasis. ( Brunnberg, L; Forterre, S; Kohn, B; Raila, J; Schweigert, FJ, 2006)
"The analyses of compositions of urinary stones can provide significant reference to the treatment and prevention of recurrence of urolithiasis."	1.33	[Application and research progress of composition analysis of urinary calculi]. ( Chen, DZ; Deng, SP; Ouyang, JM, 2006)
"Uric acid content was highest when colon surgery had occurred."	1.32	Urine stone risk factors in nephrolithiasis patients with and without bowel disease. ( Coe, FL; O'Connor, RC; Parks, JH; Worcester, EM, 2003)
"The chemical constituents of 34 feline urinary calculi and five urethral plugs were analysed by infrared spectroscopy."	1.32	Analysis of feline urinary calculi and urethral plugs by infrared spectroscopy and scanning electron microscopy. ( Bellanato, J; Escolar, E, 2003)
"We examined dissolution of urinary stones by the bacteria and studied optimal conditions for the dissolution in human urine."	1.32	A new method using a bacterium for dissolution of urinary stones. ( Aoki, K; Nishio, S; Yokoyama, M, 2003)
"Four uric acid stones were available for comparison, and three of the four matched stents tested positive for uric acid."	1.32	Comparison of urinary stone and stent encrustation: biochemical analysis. ( Bariol, S; Farebrother, T; MacNeil, F; Ruthven, S, 2003)
"A 28-year-old woman suffering from Crohn's disease since 15 years of age presented with left back pain."	1.32	[A case of ammonium urate urolithiasis with Crohn's disease]. ( Fujii, T; Shiba, M; Takatera, H, 2003)
"Calcium oxalate (about 70%) was the main composition of urinary stones in the Zhujiang valley in Guangdong province; while 30% of which was uric acid stones."	1.32	[Combined analysis of urinary stones by X-ray photoelectron spectroscopy and X-ray powder diffraction]. ( Li, XP; Ouyang, JM, 2003)
"However, the probability of stone recurrence estimated by Kaplan-Meier curves was as equivalent in the elderly patient group as in the younger group."	1.32	Urolithiasis in geriatric patients. ( Matsushita, K; Matsuzaki, S; Shima, M; Usui, Y, 2003)
"Intact human urinary stones were then analyzed by micro-CT, and regions-of-interest of pure mineral were correlated with identical regions-of-interest from quad slice multi-detector row helical CT images."	1.32	Helical computed tomography accurately reports urinary stone composition using attenuation values: in vitro verification using high-resolution micro-computed tomography calibrated to fourier transform infrared microspectroscopy. ( Evan, AP; Hatt, EK; Kim, SC; Lingeman, JE; McAteer, JA; Paterson, RF; Sommer, AJ; Tann, M; Williams, JC; Zarse, CA, 2004)
"One hundred human urinary calculi were obtained from a stone-analysis laboratory and placed in 20 excised pig kidneys."	1.32	Helical CT evaluation of the chemical composition of urinary tract calculi with a discriminant analysis of CT-attenuation values and density. ( Bellin, MF; Bissery, A; Conort, P; Daudon, M; Grenier, P; Mallet, A; Meric, JB; Renard-Penna, R; Richard, F, 2004)
"To do this, human urinary stones were sectioned with a diamond wire saw."	1.32	Nondestructive analysis of urinary calculi using micro computed tomography. ( Evan, AP; Hatt, EK; Kim, SC; Lingeman, JE; McAteer, JA; Sommer, AJ; Williams, JC; Zarse, CA, 2004)
"A 13-year-old boy with ulcerative colitis was admitted to our hospital for the purpose of controlling diarrhea."	1.31	[A pediatric case of ammonium acid urate lithiasis with ulcerative colitis]. ( Fukumori, T; Kagawa, S; Kanayama, HO; Kurokawa, Y; Oka, N; Shirane, Y; Takahasi, M; Yamamoto, Y, 2002)
"Treatment with lupeol and lupeol linoleate reduced the extent of tubular damage as evidenced from reduced enzymuria and minimized the excretion of stone forming constituents."	1.31	Evaluation of the effect of triterpenes on urinary risk factors of stone formation in pyridoxine deficient hyperoxaluric rats. ( Lenin, M; Varalakshmi, P; Vidya, L, 2002)
"Uric acid powder was suspended in solution and exposed to holmium laser energy in vitro."	1.31	Fragmentation of uric acid calculi with the holmium: YAG laser produces cyanide. ( Conlin, MJ; Waldmann, TM; Zagone, RL, 2002)
"Flank pain was the most common manifestation."	1.31	Urolithiasis in childhood. ( Gündüz, Z; Kabaklioğlu, M; Küçükaydin, M; Okur, H; Ozokutan, BH; Turan, C, 2000)
"The lack of hematuria is not predictive of absence of urolithiasis."	1.31	Hyperuricosuria in children: clinical presentation and natural history. ( Di Toro, R; Iovene, A; La Manna, A; Marte, A; Polito, C, 2001)
"Lower urinary tract stones were predominant in men 60 years of age or older."	1.31	Changes in the incidence of lower urinary tract stones in japan from 1965 to 1995. ( Ogawa, O; Ohkawa, T; Okada, Y; Terai, A; Yoshida, O, 2000)
"Uric acid was the main component of 9 stones."	1.31	[Identification and quantitation of purine derivatives in urinary calculi as markers of abnormal purine metabolism by using high-performance liquid chromatography (HPLC)]. ( Safranow, K, 2000)
"Because almost all urinary stones are formed in outpatients with ambulatory free diet, it is essential to investigate these factors in outpatients."	1.31	Role of the diurnal variation of urinary pH and urinary calcium in urolithiasis: a study in outpatients. ( Murayama, T; Sakai, N; Takano, T; Yamada, T, 2001)
"Hyperoxaluria was induced by feeding 1% ethylene glycol to rats."	1.31	Effect of hyperoxaluria on the inhibitory activity of a 45-kD urinary protein. ( Balakrishnan, S; Kalaiselvi, P; Selvam, R, 2002)
"An epidemiologic study of urinary calculi (N = 1843) was conducted in Western France: distribution according to the main chemical compounds, age and sex."	1.31	[Epidemiologic study of urinary calculi in Western France]. ( Bigot, JC; Carre, JL; Cledes, J; Decoster, M; Floch, HH; Mahé, JL; Morin, JF; Tanquerel, T, 2002)
"From 1956 to 1999, 9,715 urinary calculi were collected at a single institution and analyzed using polarizing microscopy."	1.31	Association of changes in the pattern of urinary calculi in Taiwanese with diet habit change between 1956 and 1999. ( Chen, J; Hsu, TC; Huang, HS; Wang, CJ, 2002)
"Uric acid stones were more frequently observed on the left side in both sexes (p < 0."	1.30	New aspects of urolithiasis in France. GERBAP: Groupe d'Evaluation et de Recherche des Biologistes de l'Assistance Publique des Hôpitaux de Paris. ( Daudon, M; Donsimoni, R; Fellahi, S; Hennequin, C; Lacour, B; Moël, GL; Paris, M; Troupel, S, 1997)
"Calcium oxalate monohydrate was present in 70."	1.30	[Urolithiasis in children in West Algeria]. ( Addou, A; Daudon, M; Harrache, D; Lacour, B; Mesri, A; Semmoud, A, 1997)
"Upper urinary tract stones were passed spontaneously in 13 patients and removed surgically in nine patients."	1.30	Ammonium acid urate crystal formation in adult North American stone-formers. ( Bonnardeaux, A; Boucher, A; Cardinal, J; Houde, M; Nolin, L; Ouimet, D; Pichette, V, 1997)
"Calcium oxalate particles were not of crystalluria origin but developed in the cavity."	1.30	Structure of uric acid concretion developed around a catheter. ( Costa-Bauza, A; Grases, F; Söhnel, O; Villacampa, AI, 1997)
"5706 canine urinary stones were analyzed by means of infrared spectroscopy from 1984-1996."	1.30	[Current information on the composition and breed distribution of urinary stones in dogs]. ( Albrecht, F; Bongartz, D; Graf, C; Hesse, A; Steffes, HJ, 1997)
"Uric acid stones were easily differentiated from all other stones using the absolute CT value."	1.30	Accurate determination of chemical composition of urinary calculi by spiral computerized tomography. ( Ernst, RD; Mostafavi, MR; Saltzman, B, 1998)
"A 31-year-old male with true hermaphroditism and a 46, XX karyotype who underwent gonadectomy and extirpation of the internal sex organs at the age of 4 had a large stone 4 cm in diameter in the residual male vagina."	1.30	Vaginal stone in a male patient with true hermaphroditism. ( Hashiba, T; Hosaka, M; Noguchi, K; Saitoh, K; Takeda, M; Yao, M, 1997)
"Hematuria was found in 85% of dogs in which urinalysis was performed."	1.30	Surgical treatment of urate calculi in Dalmatians: 38 cases (1980-1995). ( Birchard, SJ; Chew, DJ; Collins, RL; Heuter, KJ, 1998)
"The disorders associated with bladder stones were prostatic hyperplasia and cancer (47."	1.29	Chemical compositions of 300 lower urinary tract calculi and associated disorders in the urinary tract. ( Honda, M; Hosoya, Y; Imai, T; Maeda, S; Suzuki, T; Takasaki, E, 1995)
"Only 27% remained recurrence free, and 62% thereof also had pathologic urinary findings."	1.29	Value of repeated analyses of 24-hour urine in recurrent calcium urolithiasis. ( Höbarth, K; Hofbauer, J; Szabo, N, 1994)
"We reviewed 5477 patients with urinary calculi who presented during the years from 1975 to 1993."	1.29	[An epidemiologic study on pathogenesis of uric acid urolithiasis]. ( Hikita, M; Hosoya, T; Ichida, K; Okabe, H; Saji, M; Sakai, O; Tabe, A, 1995)
"Thirty-six urinary stones were studied by computed tomography and bone densitometry in order to find a correlation between the chemical composition of the stones and the densitometric data."	1.29	In vitro analysis of urinary calculi: type differentiation using computed tomography and bone densitometry. ( Baert, L; Boving, R; Geusens, P; Herremans, D; Oyen, R; Pittomvils, G; Vandeursen, H, 1993)
"Texture and micro-morphology of 1615 urinary calculi has been studied using scanning electron microscopy and X-ray micro analysis."	1.28	A classification of urinary calculi with respect to their composition and micromorphology. ( Leusmann, DB, 1991)
"To estimate the epidemiology of upper urinary stones in the elderly, a total of 1,957 patients (1,349 men and 608 women) with urolithiasis were studied."	1.28	Epidemiology of urolithiasis in the elderly. ( Iguchi, M; Ishikawa, Y; Kataoka, K; Katoh, Y; Kohri, K; Kurita, T; Yachiku, S, 1991)
"Calcium oxalate monohydrate was exclusively precipitated, and the individual crystals deposited in the presence of urate were markedly smaller, more numerous, and more highly aggregated than those produced in its absence."	1.28	Effect of urate on calcium oxalate crystallization in human urine: evidence for a promotory role of hyperuricosuria in urolithiasis. ( Grover, PK; Marshall, VR; Ryall, RL, 1990)
"Recurrence was seen in 16."	1.28	[Clinical study on recurrence of urinary tract lithiasis of ESWL]. ( Kato, S; Mori, K; Nakajima, H; Ohnishi, S; Tanda, H; Ujiie, T, 1990)
"Incidence of calcium-containing urinary stones in the upper urinary tract has been increasing in Japan since the Second World War with increasing westernization of life-style and industrialization, with the annual incidence of urolithiasis steadily increasing from 53."	1.28	Epidemiology of urolithiasis in Japan: a chronological and geographical study. ( Okada, Y; Yoshida, O, 1990)
"One hundred fifty specimens of urinary calculi from 150 cats were analyzed by at least 1 of 4 quantitative methods."	1.28	Epizootiologic evaluation and quantitative analysis of urinary calculi from 150 cats. ( Franti, CE; Johnson, DL; Ling, GV; Ruby, AL, 1990)
"Thirty eight patients with medullary sponge kidney (MSK) were detected (4."	1.28	[Clinical studies on medullary sponge kidney evaluated from urolithiasis]. ( Kinoshita, H, 1990)
"Uric acid, when treated with nitric acid, is stoichiometrically converted to alloxan, which is determined fluorimetrically with 1,2-phenylenediamine."	1.27	A method for quantitative wet chemical analysis of urinary calculi. ( Larsson, L; Ohman, S; Sörbo, B; Tiselius, HG, 1984)
"Application on in vivo grown urinary calculi shows that crystals of uric."	1.27	[Size and formation of crystals in urinary calculi studied with x-ray diffraction profiles]. ( Asper, R; Schmucki, O, 1984)
"A series of 178 urinary stones is analysed qualitatively during a three year period from 1980 to 1982."	1.27	Stone composition and metabolic study in urinary calculous disease. ( Foo, KT; Foong, WC; Low, CO; Tan, EC; Tung, KH, 1984)
"Excised urinary calculi were subjected to computed tomographic (CT) scanning in an attempt to determine whether CT attenuation values would allow accurate analysis of stone composition."	1.27	Computed tomographic analysis of urinary calculi. ( Amis, ES; Dretler, SP; Newhouse, JH; Pfister, RC; Prien, EL, 1984)
"Weight data for bladder stones are presented briefly and show a wide range of weights for all types of composition."	1.27	Observations on urinary stone weight correlated with composition. ( Otnes, B, 1983)
"Weddellite stones were significantly heavier and significantly higher in apatite content than whewellite stones."	1.27	Study of passed stones by means of X-rays, infrared and thermal analyses. ( Konjiki, T; Sudo, T; Tozuka, K, 1983)
"Therefore, in stone recurrence prevention, the administration of Milurit 300 is recommended."	1.27	Prevention of recurrent uric acid and calcium oxalate stones by administration of the xanthine oxidase inhibitors Milurit 100 and Milurit 300. ( Balogh, A; Brundig, P; Fünfstück, R; Schneider, HJ; Stein, G; Traeger, A, 1983)
"Calcium oxalate was the main component of both adult (49%) and childhood (44%) stones."	1.27	Urinary stone composition in North-East Thailand. ( Prasongwatana, V; Sriboonlue, P; Suntarapa, S, 1983)
"The presence of lipids in urinary stones was determined by histochemical and biochemical methods."	1.27	Presence of lipids in urinary stones: results of preliminary studies. ( Hackett, RL; Khan, SR; Shevock, PN, 1988)
"The chemical composition of 210 urinary calculi either spontaneously passed or surgically removed during January 1965-December 1968 was compared with the chemical composition of 1338 urinary calculi received during July 1982-June 86."	1.27	Chronological variation in chemical composition of urinary calculi between 1965-68 and 1982-86 in north western India. ( Malakandaiah, GC; Nath, R; Sidhu, H; Thind, SK; Vaidyanathan, S, 1988)
"As for stone recurrence rate, no difference was noted between group I and group II, III or IV."	1.27	[Clinical studies on recurrence of urolithiasis. (2) Hypercalciuria and recurrence of urolithiasis]. ( Murayama, T; Taguchi, H, 1987)
"The peak age incidence of urinary calculi occurred in the third decade."	1.27	[Statistical analysis of urolithiasis]. ( Arakawa, T; Koshiba, K; Mashimo, S; Odajima, K; Omata, T; Seiichi, K; Uchida, T; Yoshizawa, K, 1987)
"Fluoride concentrations in 42 urinary calculi were determined using a microdiffusion procedure in conjunction with a fluoride sensitive electrode."	1.27	Fluoride concentrations in a collection of urinary calculi. ( Rodgers, AL; Wandt, MA, 1987)
"Twenty-one urinary stones, classified in four groups, have been analysed."	1.27	Analysis of urinary calculi using photon induced X-ray fluorescence (XRF). ( Alpi, G; Bisceglie, V; Cesareo, R; Di Silverio, F; Gallucci, M; Pedraza, LJ, 1986)
"The frequency of recurrence was very high in the patients in their forties."	1.27	[Clinical observation of urolithiasis in Mie University Hospital]. ( Araki, T; Arima, K; Hoshina, A; Kinoshita, N; Nishii, M; Sakurai, M; Suzuki, S; Tukamoto, K; Yamakawa, K; Yanagawa, M, 1986)
"In struvite stones, which are an agglomeration of struvite and calcium phosphate crystals, major fragmentation occurred along the crystalline interfaces."	1.27	Morphology of urinary stone particles resulting from ESWL treatment. ( Finlayson, B; Hackett, RL; Khan, SR, 1986)
"Matrices of nine single urinary stones of various compositions and of three stone pools (calcium oxalate, magnesium ammonium phosphate) were isolated by exhaustive dialysis."	1.27	Glycosaminoglycans content of stone matrix. ( Resnick, MI; Roberts, SD, 1986)
"Stone analysis was performed for 216 urinary calculi which were obtained from 205 patients in our hospital from January, 1980 to June, 1984."	1.27	[A clinical study of urolithiasis in Shizuoka City Hospital--stone analysis and 24-hour urine calcium and uric acid levels]. ( Kanamaru, H; Komatz, Y; Ohshiro, K; Sasaki, M, 1985)
"The results of chemical analyses of 429 urinary calculi are presented and classified according to chemical composition."	1.26	Renal lithiasis in Lebanon: I--the chemical types of urinary calculi. ( Hemady, K; Saksouk, FA; Salti, IS, 1980)
"Three hundred urinary calculi were collected in the Durban area during the period August 1979--August 1980."	1.26	Composition of urinary calculi collected in the Durban area. ( Gray, D; Laing, M; Naudé, JH; Nel, F, 1982)
"Four of the ileostomists who had had ulcerative colitis had urinary stones (10."	1.26	Urinary stones in subjects with a permanent ileostomy. ( Fletcher, EW; Kennedy, HJ; Truelove, SC, 1982)
" From the results obtained in this study, magnesium oxide in this dosage cannot be recommended for use in treatment of patients with urolithiasis."	1.26	Urine composition in patients with urolithiasis during treatment with magnesium oxide. ( Ahlstrand, C; Larsson, L; Tiselius, HG, 1980)
"The analysis of 322 urinary calculi in adults by microdissection, infrared spectromorphometry and microchemistry has shown that stones could be classified in several groups according to their morphology and composition: 8 morphological types have been defined (2 for the oxalic, 2 for the uric, 2 for the phosphatic and 2 for the cystinic stones)."	1.26	Analysis of urinary calculi in adults. Attempt of correlations between morphology and composition. ( Ayrole, G; Daudon, M; Protat, MF; Reveillaud, RJ, 1980)
"benzbromarone were compared."	1.26	[The treatment of hyperuricemia after kidney transplantation]. ( Flury, W; Montandon, A; Ruch, HR, 1977)
"Seventy-eight urinary stones from the Sudan were analysed quantitatively; 75."	1.26	The composition of urinary stones in the Sudan. ( Kambal, A; Khattab, AH; Wahab, EM, 1979)
"Stone recurrence rates usually remain stable, or rise with successive stones; in a minority of patients, the reverse is true."	1.26	The natural history of calcium urolithiasis. ( Coe, FL; Keck, J; Norton, ER, 1977)
"Allopurinol is a drug which could be valuable in the treatment of stone patients."	1.26	The effect of allopurinol on urinary oxalate excretion in stone formers. ( Mathieson, A; Paterson, PJ; Scott, R; Smith, M, 1978)
"Of the 438 dogs, 111 had 155 known recurrences of calculi."	1.26	Recurrence of canine urolithiasis. ( Brown, NO; Greene, RW; Parks, JL, 1977)
"59% of all urinary calculi had a different phase content in the nucleus and in the calyx."	1.26	[Topographic phase analysis of urinary concrements using crystal-optic methods]. ( Bick, C; Brien, G; Gremske, D; Schubert, G, 1977)
"The composition of 1,327 urinary stones by X-ray diffraction is statistically analyzed, and the exact analyses are discussed."	1.26	[Grouping of urinary stones and exactness of analyses (author's transl)]. ( Bastian, HP; Gebhardt, M, 1976)
"Pure uric acid dihydrate was prepared according to a modified technique and the dA values (lattice distances (of A) were determined from several recordings."	1.25	Uric acid dihydrate as urinary calculus component. ( Berg, W; Hesse, A; Hienzsch, E; Schneider, HJ, 1975)
"Out of a group of 979 patients with urinary calculi, 175 had passed their stone(s)."	1.25	Some data on urinary stones which were passed. ( Sutor, DJ; Wooley, SE, 1975)
"The incidence of recurrence was 23."	1.25	[Recurrent Urolithiasis during Childhood (author's transl)]. ( Vendl, L, 1975)
"Juvenile bladder stones are typically urate and oxalate in small boys in certain stone belts."	1.25	Human stones. ( Lonsdale, K, 1968)
"A survey of 458 patients treated for ulcerative colitis either medically or surgically by colectomy and the establishment of an ileostomy has provided further evidence that in Australia at least there is a significant association between ulcerative colitis and urinary calculi."	1.25	Urinary calculi and ulcerative colitis. ( Bennett, RC; Hughes, ES, 1972)
"Allopurinol has been universally successful in lowering the serum uric acid concentration and uric acid excretion to normal levels, while not significantly affecting the clearance of urate or other aspects of renal function."	1.24	The treatment of gout and disorders of uric acid metabolism with allopurinol. ( Houpt, JB; Ogryzlo, MA; Urowitz, MB; Weber, HM, 1966)

Research

Studies (1,127)

Authors

Clinical Trials (9)

Trial Overview

Trial Outcomes

Percent Change From Baseline to Month 6 in 24-hour Urine Uric Acid (uUA) Excretion

Timeframe	Studies, this research(%)	All Research%
pre-1990	630 (55.90)	18.7374
1990's	137 (12.16)	18.2507
2000's	148 (13.13)	29.6817
2010's	155 (13.75)	24.3611
2020's	57 (5.06)	2.80

Authors	Studies
Mercurio, M	1
Izzo, F	1
Gatta, GD	1
Salzano, L	1
Lotrecchiano, G	1
Saldutto, P	1
Germinario, C	1
Grifa, C	1
Varricchio, E	1
Carafa, A	1
Di Meo, MC	1
Langella, A	1
Miyauchi, T	4
Terashita, M	1
Ogata, M	1
Murata, M	1
Osako, K	1
Imai, N	1
Sakurai, Y	1
Sasaki, H	1
Ohashi, Y	2
Ichida, K	13
Shibagaki, Y	1
Yazawa, M	1
Nitkin, DM	1
Juraha, TM	1
Gres, AA	1
Gres, NA	1
Solovey, OM	1
Ban, H	1
Miura, K	1
Tomoeda, R	1
Hirai, K	1
Hattori, M	1
Koto, R	1
Sato, I	1
Kuwabara, M	6
Seki, T	1
Kawakami, K	1
Wen, W	1
Li, Y	1
Chen, Q	1
Li, J	4
Sánchez, R	1
Navarro, P	1
Troncoso, MP	1
López, C	1
Salvadó, JA	1
El Beze, J	1
Mazeaud, C	1
Daul, C	1
Ochoa-Ruiz, G	1
Daudon, M	18
Eschwège, P	1
Hubert, J	1
Abdel-Gawad, M	1
Ali-El-Dein, B	1
Elsobky, E	1
Mehta, S	1
Alsaigh, N	1
Knoll, T	1
Kura, M	1
Kamphuis, G	1
Alhayek, S	1
Alkohlany, K	1
Buchholz, N	2
Monga, M	3
Henderickx, MMEL	1
Stoots, SJM	1
De Bruin, DM	1
Wijkstra, H	1
Freund, JE	1
Wiseman, OJ	1
Ploumidis, A	1
Skolarikos, A	1
Somani, BK	2
Şener, TE	1
Emiliani, E	1
Dragos, LB	1
Villa, L	1
Talso, M	1
Traxer, O	2
Kronenberg, P	1
Doizi, S	1
Tailly, T	1
Tefik, T	1
Hendriks, N	1
Beerlage, HP	1
Baard, J	1
Kamphuis, GM	1
Siener, R	10
Herwig, H	1
Rüdy, J	1
Schaefer, RM	1
Lossin, P	1
Hesse, A	22
Kim, US	1
Kwon, HS	1
Yang, W	1
Lee, W	1
Choi, C	1
Kim, JK	1
Lee, SH	1
Rim, D	1
Han, JH	1
Kim, JY	1
Yu, JH	1
Kang, SH	1
Lee, JG	1
Cheon, J	1
Kang, SG	1
Strohmaier, WL	2
Neisius, A	2
Michael, KGFT	1
Michael, S	1
Abusada, E	1
Srirangam, SJ	1
Bourdoumis, A	1
Surange, R	1
Bruwier, A	1
Godart, B	1
Gatel, L	1
Leperlier, D	1
Bedu, AS	1
Ubetagoyena, M	1
Areses, R	1
Mendia, J	1
Perez, M	1
Aierken, Y	1
Ye, E	1
Abudureyimu, A	1
Li, SX	1
Kadier, A	1
Keyoumu, H	1
Liu, D	2
Miyazaki, S	4
Hamada, T	5
Isoyama, T	3
Okada, S	3
Tomita, K	4
Endo, Y	3
Sugihara, S	4
Ogino, K	5
Ninomiya, H	4
Yamamoto, K	5
Takenaka, A	3
Hisatome, I	8
Mazzierli, T	3
Cirillo, L	3
Palazzo, V	3
Ravaglia, F	3
Becherucci, F	3
Ernsten, C	2
Bitterlich, N	2
Alteheld, B	2
Metzner, C	2
Li, X	3
Tang, P	2
Liang, F	2
Wang, L	2
Huang, X	2
Zhen, X	2
Klib, M	1
Ghandour, M	1
Wannous, H	1
Liu, J	1
Gao, D	1
Wang, J	2
Liu, M	1
Yu, D	1
Cachau, R	1
Shahsavari, S	1
Cho, SK	1
Tallman, JE	1
Stone, BV	1
Sui, W	1
Miller, NL	1
Hsi, RS	1
Jung, JW	1
Shin, JB	1
Choi, HJ	1
Pak, S	1
Yang, H	1
Yoon, BI	1
Euler, A	2
Wullschleger, S	1
Sartoretti, T	2
Müller, D	2
Keller, EX	1
Lavrek, D	1
Donati, O	1
Ong, A	1
Brown, G	1
Tokas, T	1
Hameed, BMZ	1
Philip, J	1
Zreik, R	1
Pilosov Solomon, I	1
Saliba, W	1
Tor, R	1
Cohen, S	1
Friefeld, Y	1
Dekel, Y	1
Klein, I	1
Song, S	1
Yao, J	1
Liao, X	1
Chen, M	5
Zhai, J	1
Lang, L	1
Lin, C	1
Zhang, N	1
Yuan, C	1
Li, C	3
Li, H	2
Wu, X	1
Lin, J	1
Wang, Y	1
Lyu, J	1
Li, M	3
Zhou, Z	2
Yang, M	1
Jia, H	1
Yan, J	1
Pranovich, AA	1
Kalinin, DV	1
Sultanova, NO	1
Stepanova, YA	1
Borukaev, AY	1
Protoshchak, VV	1
Paronnikov, MV	1
Babkin, PA	1
Sleptsov, AV	1
Song, BI	1
Lee, J	1
Jung, W	1
Kim, BS	1
DeBow, P	1
Auger, M	1
Fazio, C	1
Cline, K	1
Zhu, X	1
Lulich, J	1
de Swarte, M	1
Lamb, D	1
Hespel, AM	1
Chew, BH	1
Wong, VKF	1
Halawani, A	1
Lee, S	1
Baek, S	1
Kang, H	1
Koo, KC	1
Modou, N	1
Mohamed, D	1
Motoula Latou, L	1
Racine, K	1
Lamine, N	1
Dominique, D	1
Mohamed, SS	1
Demidko, LS	1
Rudenko, VI	2
Fadeev, VV	1
Demidko, YL	1
Amosov, AV	1
Kuzmicheva, GM	1
Grigoryan, VA	1
Enikeev, ME	1
Amosova, MV	1
Hu, L	1
Hu, G	1
Xu, BP	1
Zhu, L	1
Zhou, W	1
Wang, T	1
Bao, H	1
Cheng, X	2
Furuto, Y	1
Kawamura, M	1
Namikawa, A	1
Takahashi, H	1
Shibuya, Y	1
Mori, T	2
Sohara, E	2
Große Hokamp, N	1
Lennartz, S	1
Salem, J	1
Pinto Dos Santos, D	1
Heidenreich, A	1
Maintz, D	1
Haneder, S	1
Kapanadze, LB	1
Serova, NS	1
Rapoport, LM	2
Aleksandrova, KA	1
Novikov, AA	1
McGrath, TA	1
Frank, RA	1
Schieda, N	1
Blew, B	1
Salameh, JP	1
Bossuyt, PMM	1
McInnes, MDF	1
Sebesta, I	7
Miyamoto, D	1
Stiburkova, B	8
Blahova, S	1
Sato, N	1
Nagata, K	1
Okamoto, K	1
Tsuruoka, S	1
Sekiya, M	1
Matsuda, T	1
Yamamoto, Y	2
Furuta, Y	1
Ohyama, M	1
Murayama, Y	1
Sugano, Y	1
Ohsaki, Y	1
Iwasaki, H	1
Yahagi, N	1
Yatoh, S	1
Suzuki, H	1
Shimano, H	1
Tsuji, K	1
Kitamura, M	1
Muta, K	1
Mochizuki, Y	1
Uchida, S	4
Sakai, H	1
Mukae, H	1
Nishino, T	1
Park, JH	1
Jo, YI	1
Lee, JH	2
Nakhostin, D	1
Eberhard, M	1
Krauss, B	1
Alkadhi, H	3
Trinchieri, A	3
Maletta, A	1
Simonelli, G	1
Boeri, L	1
De Lorenzis, E	1
Montanari, E	2
Gudeloglu, A	1
Haberal, HB	1
Aydanal, M	1
Asci, A	1
Yucel Bilen, C	1
Jendeberg, J	1
Thunberg, P	1
Popiolek, M	1
Lidén, M	2
Adomako, E	1
Moe, OW	2
Burggraaf, ND	1
Westgeest, DB	1
Corbee, RJ	1
Aghajari, S	1
Sabzalipour, S	1
Nazarpour, A	1
Rozbahani, MM	1
Estrade, V	1
Richard, E	1
Bernhard, JC	1
Bladou, F	1
Robert, G	1
Denis de Senneville, B	1
Kuntima Diasiama, PD	1
Moningo Molamba, D	1
Makulo Rissasy, JR	1
Sumaili Kiswaya, E	1
Mafuta Musalu, É	1
Ngoma, A	1
Loposso Nkumu, M	1
Punga-Maole, A	1
Lwa Nkandi, SL	1
Haymann, JP	1
Jung, HD	1
Seo, IY	1
Lee, JY	1
Nell, E	1
Garofolo, SQ	1
Ober, C	1
Li, S	3
Iremashvili, V	1
Vernez, SL	1
Penniston, KL	3
Jhagroo, RA	2
Best, SL	2
Hedican, SP	1
Nakada, SY	3
Plante, G	1
Ouimet, D	2
Robitaille, R	1
Ma, RH	1
Luo, XB	1
Li, Q	1
Zhong, HQ	1
Birke, LL	1
Cespedes, AM	1
Schachner, ER	1
Lailvaux, SP	1
Altan, M	1
Çitamak, B	1
Bozaci, AC	1
Güneş, A	1
Doğan, HS	1
Haliloğlu, M	1
Tekgül, S	1
Niwa, K	2
Ohtahara, A	1
Mizuta, E	1
D'Alessandro, MM	1
Gennaro, G	1
Tralongo, P	1
Maringhini, S	1
Tanaka, Y	2
Hatakeyama, S	1
Tanaka, T	1
Yamamoto, H	1
Narita, T	1
Hamano, I	1
Matsumoto, T	1
Soma, O	1
Okamoto, T	1
Tobisawa, Y	1
Yoneyama, T	2
Hashimoto, Y	2
Koie, T	1
Takahashi, I	1
Nakaji, S	1
Terayama, Y	1
Funyu, T	1
Ohyama, C	1
Assimos, DG	5
Chu, FY	1
Chang, CC	1
Huang, PH	1
Lin, YN	1
Ku, PW	1
Sun, JT	1
Ho, JL	1
Yen, TH	1
Su, MJ	1
Ganesan, V	1
De, S	1
Shkumat, N	1
Marchini, G	1
Nykamp, SG	1
Neheman, A	1
Korzets, Z	1
Stackievicz, R	1
Itzhaki, T	1
Pula, G	1
Pomeranz, G	1
Greenberg, M	1
Adam, D	1
Pomeranz, A	1
Franken, A	1
Gevenois, PA	1
Muylem, AV	1
Howarth, N	1
Keyzer, C	1
Baroni, S	1
Garigali, G	1
Primiano, A	1
Gervasoni, J	1
Fogazzi, GB	1
Jungers, P	3
Bazin, D	1
Williams, JC	4
Ferrero, A	1
Gutjahr, R	1
Halaweish, AF	1
Leng, S	2
McCollough, CH	2
Ananthakrishnan, L	1
Duan, X	2
Xi, Y	1
Lewis, MA	1
Pearle, MS	4
Antonelli, JA	1
Goerne, H	1
Kolitz, EM	1
Abbara, S	1
Lenkinski, RE	1
Fielding, JR	1
Leyendecker, JR	1
Luo, J	1
Tuerxun, A	2
Shataer, A	1
Batuer, A	2
Jiang, C	1
Zhou, Y	1
Li, Z	2
Chen, D	1
Liu, Y	4
Krijt, J	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Losartan and Uric Acid Metabolism in Children With Proteinuric Nephropathies: a Cross-over Randomized Clinical Trail[NCT05402397]	Phase 4	40 participants (Anticipated)	Interventional	2022-07-01	Recruiting
A Multicenter, Randomized, Double-Blind, Placebo and Allopurinol Controlled, Phase 2 Study to Evaluate Febuxostat in the Medical Management of Subjects With Hyperuricosuria and Calcium Oxalate Stones[NCT01077284]	Phase 2	99 participants (Actual)	Interventional	2010-02-28	Completed
Evaluating Post-operative Pain Management Efficacy of Intra Nasal Ketorolac in Ambulatory Urological Surgeries-A Randomized Double-blinded Placebo Controlled Study[NCT01736358]	Phase 4	50 participants (Actual)	Interventional	2012-10-31	Terminated (stopped due to Interim analysis showed futility of primary endpoint)
Does Potassium Citrate Supplementation Reduce Stone Recurrence in Calcium Phosphate Stone Formers With Risk Factors?[NCT01980004]	Phase 2	0 participants (Actual)	Interventional	2013-11-30	Withdrawn (stopped due to closure due to failure to recruit any patients that met study criteria)
Clinical Investigation of Aging Men With Renal Stones: The Role of Bone Demineralization (Metabolic and Hormonal Assessment)[NCT01246531]		42 participants (Actual)	Observational	2008-01-31	Completed
Maintenance of an Antiaggregation by Acetylsalicylic Acid, Less or Equal to 250mg While a Extracorporeal Lithotripsy (ECL) Session on a Kidney Stone is Perfomed: Comparative Unicentric Prospective Study[NCT03437057]		300 participants (Anticipated)	Interventional	2018-01-08	Recruiting
Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention[NCT05627622]		200 participants (Anticipated)	Interventional	2021-01-01	Recruiting
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)[NCT04073719]		50 participants (Anticipated)	Interventional	2019-09-01	Not yet recruiting
A Randomized, Blank Controlled, Multicenter Clinical Trial of the Effection of Potassium Citrate Extended-release Tablets on Urolithiasis Formation or Recurrence[NCT03007160]	Phase 4	2,001 participants (Anticipated)	Interventional	2016-07-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

The change from Baseline to Month 6 in 24-hour urine uric acid is expressed as a percentage of the Baseline uUA value. (NCT01077284)
Timeframe: Baseline and Month 6

Percent Change From Baseline to Month 6 in the In-plane Diameter of the Largest Calcium Oxalate (CaOx) Stone

Intervention	percent change (Mean)
Febuxostat	-58.6
Allopurinol	-36.4
Placebo	-12.7

Multidetector Computed Tomography (MDCT) was used to visualize and measure calcium oxalate kidney stones at Baseline and after 6 months of treatment. All MDCT images were analyzed independently by a Central Reader. The change from Baseline to month 6 is expressed as a percentage of the Baseline largest in-plane diameter. (NCT01077284)
Timeframe: Baseline and Month 6

Change From Baseline to Month 6 in 24-hour Measured Creatinine Clearance

Intervention	percent change (Mean)
Febuxostat	-6.50
Allopurinol	0.63
Placebo	3.20

Creatinine clearance is a measure of how well the kidneys are filtering creatinine, a waste product produced by the muscles. Measured creatinine clearance was calculated according to the following: Urine 24 hour Creatinine/Serum Creatinine x (total Urine volume/elapsed time) x (1.73/body surface area). (NCT01077284)
Timeframe: Baseline and Month 6

Change From Baseline to Month 6 in the Number of Calcium Oxalate Stones

Intervention	mL/min/1.73m² (Mean)
	Baseline (n=33, 33, 33)	Change from Baseline (n=30, 29, 30)
Allopurinol	146.0	-7.7
Febuxostat	146.9	-9.0
Placebo	147.1	-19.0

Multidetector Computed Tomography (MDCT) was used to visualize and count calcium oxalate kidney stones at Baseline and after 6 months of treatment. All MDCT images were analyzed independently by a Central Reader. (NCT01077284)
Timeframe: Baseline and Month 6

Incidence of Postoperative Side Effects

Intervention	stones (Mean)
	Baseline (n=28, 24, 30)	Change from Baseline (n=26, 23, 26)
Allopurinol	6.60	0.28
Febuxostat	4.84	-0.06
Placebo	5.57	0.10

To find the incidence of immediate (until discharge) and 24hrs post operative side effects in the target population. (NCT01736358)
Timeframe: 24 hours after procedure

Post Operative Pain Scale

Intervention	number of events (Number)
Intranasal Ketoralac	0
Placebo	0

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 2 hours after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 2 hours after surgery

Post Operative Pain Score

Intervention	score on a scale (Median)
Intranasal Ketoralac	4
Placebo	3

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 1 hour after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 1 hour after surgery

Post Operative Pain Score

Intervention	score on a scale (Median)
Intranasal Ketoralac	3.5
Placebo	4.5

To evaluate the post operative pain score using the Visual Analog Scale (VAS) 30 minutes after surgery. The scale for VAS is 0 is no pain to 10 being the worst pain. (NCT01736358)
Timeframe: 30 minutes after surgery

Post-operative Opioid Requirements

Intervention	score on a scale (Median)
Intranasal Ketoralac	4
Placebo	3.5

this study will assess the effect of perioperative usage of single-dose of intranasal ketorolac on post operative opioid requirements within 3 hours after surgery. (NCT01736358)
Timeframe: 3 hours after surgery

Article	Year
Renal hypouricemia in a recipient of living-donor kidney transplantation: a case report and literature review. CEN case reports, 2022, Volume: 11, Issue:2 Topics: Aged; Female; Humans; Kidney; Kidney Transplantation; Living Donors; Male; Organic Anion Transporter	2022
[Urolithiasis-Therapy and recurrence prevention taking into account gender-specific aspects]. Urologie (Heidelberg, Germany), 2022, Volume: 61, Issue:10 Topics: Calcium Oxalate; Female; Humans; Male; Struvite; Uric Acid; Urinary Calculi; Urolithiasis	2022
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Clinical features suggesting renal hypouricemia as the cause of acute kidney injury: a case report and review of the literature. Journal of nephrology, 2023, Volume: 36, Issue:3 Topics: Acute Kidney Injury; Humans; Renal Tubular Transport, Inborn Errors; Uric Acid; Urinary Calculi	2023
Selection and Outcomes for Dissolution Therapy in Uric Acid Stones: A Systematic Review of Literature. Current urology reports, 2023, Volume: 24, Issue:8 Topics: Conservative Treatment; Humans; Kidney Calculi; Nephrolithiasis; Solubility; Uric Acid; Urinary Calc	2023
Diagnostic accuracy of dual-energy computed tomography (DECT) to differentiate uric acid from non-uric acid calculi: systematic review and meta-analysis. European radiology, 2020, Volume: 30, Issue:5 Topics: Diagnosis, Differential; Humans; Radiography, Dual-Energy Scanned Projection; Reproducibility of Res	2020
Renal effects of uric acid: hyperuricemia and hypouricemia. The Korean journal of internal medicine, 2020, Volume: 35, Issue:6 Topics: Adolescent; Adult; Biomarkers; Child; Disease Progression; Female; Humans; Hyperuricemia; Kidney; Re	2020
Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator. Seminars in nephrology, 2020, Volume: 40, Issue:6 Topics: Animals; Calcium Oxalate; Humans; Kidney Diseases; Uric Acid; Urinary Calculi; Urolithiasis	2020
Uric acid stones, clinical manifestations and therapeutic considerations. Postgraduate medical journal, 2018, Volume: 94, Issue:1114 Topics: Drug Therapy; Humans; Lithotripsy; Pain Management; Tomography, X-Ray Computed; Ureteroscopy; Uric A	2018
[Urate urolithiasis: pathogenesis and possibilities of conservative therapy]. Urologiia (Moscow, Russia : 1999), 2018, Issue:5 Topics: Conservative Treatment; Humans; Uric Acid; Urinary Calculi; Urolithiasis	2018
Crystalluria. Clinical chemistry and laboratory medicine, 2015, Volume: 53 Suppl 2 Topics: Biomarkers; Calcium Oxalate; Calcium Phosphates; Crystallization; Humans; Metabolic Diseases; Micros	2015
National Profiles of Urinary Calculi: a Comparison Between Developing and Developed Worlds. Iranian journal of kidney diseases, 2016, Volume: 10, Issue:2 Topics: Age Distribution; Calcium Oxalate; Calcium Phosphates; Developed Countries; Developing Countries; Di	2016
Herbal medicines for urinary stone treatment. A systematic review. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2016, Mar-31, Volume: 88, Issue:1 Topics: Calcium; Citric Acid; Humans; Oxalic Acid; Phytotherapy; Plant Preparations; Plants, Medicinal; Rand	2016
Dual-energy computed tomography for characterizing urinary calcified calculi and uric acid calculi: A meta-analysis. European journal of radiology, 2016, Volume: 85, Issue:10 Topics: Area Under Curve; Diagnosis, Differential; Humans; Radiography, Dual-Energy Scanned Projection; ROC	2016
Changing paradigms in the frequency and management of canine compound uroliths. The Veterinary clinics of North America. Small animal practice, 2009, Volume: 39, Issue:1 Topics: Animals; Breeding; Calcium Oxalate; Dog Diseases; Dogs; Female; Magnesium Compounds; Male; Phosphate	2009
Pediatric stone disease. Current urology reports, 2009, Volume: 10, Issue:2 Topics: Animals; Child; Comorbidity; Diagnostic Imaging; Humans; Hyperoxaluria; Length of Stay; Lithotripsy;	2009
Metaphylaxis of urolithiasis. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2009, Volume: 81, Issue:1 Topics: Algorithms; Calcium; Diet Therapy; Feeding Behavior; Fluid Therapy; Humans; Hypercalciuria; Life Sty	2009
[Impact of serum uric acid level on the cardiovascular system as a risk factor]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 136, Issue:6 Topics: Adipokines; Benzbromarone; Cardiovascular Diseases; Hyperuricemia; Kidney; Organic Anion Transporter	2010
Hypouricemia and tubular transport of uric acid. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:1 Topics: Absorption; Biological Transport; Diabetes Complications; Diagnosis, Differential; Fluid Therapy; Gl	2011
[Hyperuricemia and uro-nephrological disorders]. Presse medicale (Paris, France : 1983), 2011, Volume: 40, Issue:9 Pt 1 Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diagnosis, Differential; Humans; Hypertension; H	2011
[Relationship between metabolic syndrome and urinary stone disease]. Clinical calcium, 2011, Volume: 21, Issue:10 Topics: Animals; Female; Humans; Insulin Resistance; Intra-Abdominal Fat; Life Style; Male; Metabolic Syndro	2011
Asymptomatic hyperuricemia: to treat or not to treat. Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:8 Topics: Age Factors; Allopurinol; Cardiovascular Diseases; Clinical Trials as Topic; Gout; Gout Suppressants	2002
Intermittent versus continuous alkaline therapy for uric acid stones and ureteral stones of uncertain composition. Urology, 2002, Volume: 60, Issue:3 Topics: Citrates; Drug Administration Schedule; Humans; Hydrogen-Ion Concentration; Potassium Citrate; Radio	2002
[Hereditary renal hypouricemia]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1 Topics: Acute Kidney Injury; Carrier Proteins; Exercise; Humans; Kidney; Organic Anion Transporters; Organic	2003
Epidemiology and medical management of stone disease. BJU international, 2003, Volume: 91, Issue:8 Topics: Calcium Phosphates; Humans; Infant, Newborn; Risk Factors; Secondary Prevention; Uric Acid; Urinary	2003
Uric acid stone disease. Frontiers in bioscience : a journal and virtual library, 2003, Sep-01, Volume: 8 Topics: Animals; Humans; Kidney Calculi; Metabolism, Inborn Errors; Uric Acid; Urinary Calculi	2003
Tamm-Horsfall glycoprotein: biology and clinical relevance. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:4 Topics: Escherichia coli; Humans; Mucoproteins; Mutation; Nephritis, Interstitial; Protein Binding; Structur	2003
[Two cases of ammonium acid urate urinary stones related to anorexia nervosa and laxative abuse]. Hinyokika kiyo. Acta urologica Japonica, 2004, Volume: 50, Issue:3 Topics: Adolescent; Adult; Anorexia Nervosa; Cathartics; Female; Humans; Lithotripsy; Substance-Related Diso	2004
Medical management of pediatric stone disease. The Urologic clinics of North America, 2004, Volume: 31, Issue:3 Topics: Calcium; Child; Cystinuria; Humans; Hyperoxaluria, Primary; Magnesium Compounds; Phosphates; Struvit	2004
Cellular and molecular gateways to urolithiasis: a new insight. Urologia internationalis, 2005, Volume: 74, Issue:3 Topics: Animals; Apoptosis; Biological Transport, Active; Calcium; Crystallization; Cysteine; Humans; Magnes	2005
Urolithiasis in adolescent children. Adolescent medicine clinics, 2005, Volume: 16, Issue:1 Topics: Adolescent; Calcium; Cystinuria; Food; Humans; Uric Acid; Urinary Calculi; Xanthine	2005
Urolithiasis in adults. Clinical and biochemical aspects. Saudi medical journal, 2005, Volume: 26, Issue:5 Topics: Adult; Calcium; Diet; Drinking; Female; Humans; Male; Oxalates; Oxalic Acid; Risk Factors; Uric Acid	2005
Supersaturation and renal precipitation: the key to stone formation? Urological research, 2006, Volume: 34, Issue:2 Topics: Animals; Calcium; Chemical Precipitation; Circadian Rhythm; Humans; Oxalates; Phosphates; Solubility	2006
[Hyperuricemic nephropathy: Pathogenesis, pathophysiology, and therapy]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: DNA-Binding Proteins; Gout; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperuricemia; Kidney Diseases	2006
[Urinary stone disease indicating genetic background]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2 Topics: Acidosis, Renal Tubular; Amino Acids; Calcium; Carbohydrate Dehydrogenases; Carrier Proteins; Chlori	2006
Medical evaluation and treatment of urolithiasis. Pediatric clinics of North America, 2006, Volume: 53, Issue:3 Topics: Adolescent; Calcium Metabolism Disorders; Child; Child, Preschool; Cystinuria; Humans; Hyperoxaluria	2006
[Hypouricemia]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, May-10, Volume: 95, Issue:5 Topics: Acute Kidney Injury; Animals; Carrier Proteins; Exercise; Humans; Kidney Tubules; Mutation; Organic	2006
Prevention of stone disease. Urologia internationalis, 2007, Volume: 79 Suppl 1 Topics: Allopurinol; Calcium Oxalate; Cystine; Diet; Dietary Supplements; Drinking; Humans; Life Style; Rena	2007
[Urinary lithiasis secondary to intestinal diseases]. Presse medicale (Paris, France : 1983), 1983, Nov-19, Volume: 12, Issue:42 Topics: Humans; Intestinal Diseases; Oxalates; Uric Acid; Urinary Calculi	1983
Uric acid metabolism in the Dalmatian coach hound. Journal of the South African Veterinary Association, 1982, Volume: 53, Issue:3 Topics: Animals; Dogs; Humans; Kidney; Liver; Uric Acid; Urinary Calculi	1982
[Role of dietary factors in the pathogenesis of calcium urolithiasis]. Polskie Archiwum Medycyny Wewnetrznej, 1982, Volume: 68, Issue:4 Topics: Calcium; Diet; Dietary Carbohydrates; Dietary Proteins; Humans; Magnesium; Oxalates; Phosphates; Uri	1982
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Nutritional aspects of urolithiasis. Southern medical journal, 1981, Volume: 74, Issue:1 Topics: Adult; Ascorbic Acid; Calcium Oxalate; Diet; Humans; Magnesium; Male; Nutritional Physiological Phen	1981
Clinical and metabolic aspects of urinary stone disease in Leeds. Scandinavian journal of urology and nephrology. Supplementum, 1980, Volume: 53 Topics: Adolescent; Adult; Aged; Bacterial Infections; Calcium; Calcium Oxalate; Child; Crystallization; Cys	1980
Urolithiasis update: biophysical and radiologic advances enhance antistone therapy. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1981, Volume: 1, Issue:2 Topics: Calcium Oxalate; Crystallization; Crystallography; Diet Therapy; Humans; Kidney Calculi; Radiography	1981
Hematuria associated with hypercalciuria and hyperuricosuria: a practical approach. Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:6 Topics: Calcium; Child, Preschool; Female; Hematuria; Humans; Infant; Infant, Newborn; Male; Uric Acid; Urin	1994
Urate and calcium oxalate stones: from repute to rhetoric to reality. Mineral and electrolyte metabolism, 1994, Volume: 20, Issue:6 Topics: Allopurinol; Calcium Oxalate; Glycosaminoglycans; Gout; Humans; Hydrogen-Ion Concentration; Hyperoxa	1994
Uric acid nephrolithiasis. Mineral and electrolyte metabolism, 1994, Volume: 20, Issue:6 Topics: Allopurinol; Diet; Humans; Kidney; Kidney Calculi; Models, Biological; Purines; Uric Acid; Urinary C	1994
[Hyperuricemia]. Ugeskrift for laeger, 1994, Apr-18, Volume: 156, Issue:16 Topics: Gout; Humans; Kidney Diseases; Uric Acid; Urinary Calculi	1994
Metabolic and genetic aspects of urate urolithiasis in Dalmatians. Journal of the American Veterinary Medical Association, 1993, Sep-15, Volume: 203, Issue:6 Topics: Animals; Breeding; Dog Diseases; Dogs; Genes, Recessive; Genetic Linkage; Kidney; Liver; Multigene F	1993
Diagnosis, prevention, and treatment of urate urolithiasis in Dalmatians. Journal of the American Veterinary Medical Association, 1993, Sep-15, Volume: 203, Issue:6 Topics: Allopurinol; Animal Feed; Animals; Breeding; Dog Diseases; Dogs; Drinking; Hydrogen-Ion Concentratio	1993
Pediatric urolithiasis: medical and surgical management. Urology, 1996, Volume: 47, Issue:3 Topics: Calcium; Child; Citrates; Cystine; Humans; Hyperoxaluria; Lithotripsy; Nephrostomy, Percutaneous; Ur	1996
Feline urolithiasis. Etiology and pathophysiology. The Veterinary clinics of North America. Small animal practice, 1996, Volume: 26, Issue:2 Topics: Animals; Calcium Oxalate; Calcium Phosphates; Cat Diseases; Cats; Cystine; Magnesium Compounds; Phos	1996
Feline crystalluria. Detection and interpretation. The Veterinary clinics of North America. Small animal practice, 1996, Volume: 26, Issue:2 Topics: Animals; Calcium Oxalate; Calcium Phosphates; Cat Diseases; Cats; Crystallization; Hydrogen-Ion Conc	1996
Urolith analysis. Submission, methods, and interpretation. The Veterinary clinics of North America. Small animal practice, 1996, Volume: 26, Issue:2 Topics: Animals; Cat Diseases; Cats; Cystine; Oxalates; Phosphates; Uric Acid; Urinary Calculi; Urinary Cath	1996
Uric acid stones. Seminars in nephrology, 1996, Volume: 16, Issue:5 Topics: Gout; Humans; Uric Acid; Urinary Calculi	1996
[Hyperuricosuria and urolithiasis]. Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12 Topics: Calcium Oxalate; Gout; Humans; Uric Acid; Urinary Calculi	1996
[Renal hypouricemia]. Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12 Topics: Acute Kidney Injury; Biological Transport; Kidney Tubules; Purine-Pyrimidine Metabolism, Inborn Erro	1996
Metabolic evaluation of patients with stone disease. Urologia internationalis, 1997, Volume: 59, Issue:3 Topics: Calcium; Calcium Oxalate; Calcium Phosphates; Cystine; Female; Humans; Kidney Tubules; Male; Risk Fa	1997
[Urinary lithiasis: epidemiology and physiopathology]. Acta urologica Belgica, 1997, Volume: 65, Issue:3 Topics: Adult; Age Factors; Aged; Calcium; Chemical Phenomena; Chemistry, Physical; Climate; Crystallization	1997
[Hereditary renal hypouricemia]. Ryoikibetsu shokogun shirizu, 1998, Issue:19 Pt 2 Topics: Biomarkers; Creatinine; Diagnosis, Differential; Humans; Kidney Tubules, Proximal; Prognosis; Renal	1998
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The physiologic approach to the medical management of stone disease. The Urologic clinics of North America, 1998, Volume: 25, Issue:4 Topics: Acetazolamide; Calcium; Carbonic Anhydrase Inhibitors; Citrates; Cystinuria; Humans; Hyperoxaluria;	1998
Analysis of 77,000 canine uroliths. Perspectives from the Minnesota Urolith Center. The Veterinary clinics of North America. Small animal practice, 1999, Volume: 29, Issue:1 Topics: Age Distribution; Animals; Calcium Oxalate; Calcium Phosphates; Cystine; Dog Diseases; Dogs; Magnesi	1999
Canine urate urolithiasis. Etiopathogenesis, diagnosis, and management. The Veterinary clinics of North America. Small animal practice, 1999, Volume: 29, Issue:1 Topics: Animals; Breeding; Diet; Dog Diseases; Dogs; Risk Factors; Uric Acid; Urinary Calculi	1999
Urine is a saturated equilibrium and not a metastable supersaturated solution: evidence from crystalluria and the general composition of calcium salt and uric acid calculi. Urological research, 1999, Volume: 27, Issue:5 Topics: Calcium; Crystallization; Humans; Salts; Uric Acid; Urinary Calculi; Urine	1999
Is there a role for uric acid in an animal model of calcium phosphate nephrocalcinosis and calcium phosphate crystallization in urine of patients with idiopathic calcium urolithiasis? An orientational study. Journal of endourology, 1999, Volume: 13, Issue:9 Topics: Animals; Calcium; Calcium Phosphates; Crystallization; Disease Models, Animal; Humans; Nephrocalcino	1999
Chemolysis of urinary calculi. The Urologic clinics of North America, 2000, Volume: 27, Issue:2 Topics: Calcium Oxalate; Cystine; Humans; Magnesium Compounds; Phosphates; Struvite; Therapeutic Irrigation;	2000
Leave no "stone" unturned: understanding the genetic bases of calcium-containing urinary stones in children. Advances in pediatrics, 2000, Volume: 47 Topics: Adult; Age Factors; Calcium; Calcium Oxalate; Child; Cystinuria; Diagnosis, Differential; Diet; Huma	2000
CT and stone fragility. Journal of endourology, 2001, Volume: 15, Issue:1 Topics: Calcium; Calcium Oxalate; Calcium Phosphates; Cystine; Humans; Tomography, X-Ray Computed; Uric Acid	2001
Evaluation of urinary tract calculi in children. Archives of disease in childhood, 2001, Volume: 84, Issue:4 Topics: Calcium; Child; Child, Preschool; Cystine; Female; Hematuria; Humans; Kidney Calculi; Magnesium Comp	2001
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Renal handling of urate and oxalate: possible implications for urolithiasis. Urological research, 1979, Volume: 7, Issue:3 Topics: Alkalies; Animals; Diuretics; Dogs; Haplorhini; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal;	1979
Nutrition and urolithiasis. The New England journal of medicine, 1978, Jan-12, Volume: 298, Issue:2 Topics: Calcium; Cystine; Cystinuria; Humans; Nutritional Physiological Phenomena; Oxalates; Phosphates; Uri	1978
[Gout. Diagnosis--pathogenesis--therapy]. Fortschritte der Medizin, 1978, Mar-30, Volume: 96, Issue:12 Topics: Allopurinol; Balneology; Benzofurans; Crystallization; Diagnosis, Differential; Exercise Therapy; Gl	1978
Jejunoileal bypass for morbid obesity. A critical appraisal. The American journal of medicine, 1978, Volume: 64, Issue:3 Topics: Adaptation, Physiological; Adult; Blood Glucose; Blood Pressure; Body Weight; Cholelithiasis; Humans	1978
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2,8-Dihydroxyadeninuria--or when is a uric acid stone not a uric acid stone? Clinical nephrology, 1979, Volume: 12, Issue:5 Topics: Acute Kidney Injury; Adenine; Adenine Phosphoribosyltransferase; Allopurinol; Diagnosis, Differentia	1979
Urolithiasis complicating inflammatory bowel disease. The Journal of urology, 1992, Volume: 148, Issue:3 Pt 2 Topics: Humans; Inflammatory Bowel Diseases; Oxalates; Uric Acid; Urinary Calculi	1992
Urinary calculi associated with purine metabolism. Uric acid nephrolithiasis. Endocrinology and metabolism clinics of North America, 1990, Volume: 19, Issue:4 Topics: Adenine Phosphoribosyltransferase; Humans; Kidney Calculi; Lesch-Nyhan Syndrome; Purines; Risk Facto	1990
Idiopathic calcium oxalate urolithiasis. Endocrinology and metabolism clinics of North America, 1990, Volume: 19, Issue:4 Topics: Calcium; Humans; Hydrogen-Ion Concentration; Hyperoxaluria; Uric Acid; Urinary Calculi; Urine	1990
[Three decades of alkalizing treatment of urolithiasis]. Anales de la Real Academia Nacional de Medicina, 1990, Volume: 107, Issue:2 Topics: Alkalies; Diuresis; History, 20th Century; Humans; Uric Acid; Urinary Calculi; Urology	1990
Metabolic evaluation of urolithiasis. The Urologic clinics of North America, 1990, Volume: 17, Issue:1 Topics: Calcium; Cystine; Humans; Magnesium; Magnesium Compounds; Metabolic Diseases; Phosphates; Struvite;	1990
Does hyperuricosuria play a role in calcium oxalate lithiasis? The Journal of urology, 1989, Volume: 141, Issue:3 Pt 2 Topics: Allopurinol; Calcium Oxalate; Humans; Uric Acid; Urinary Calculi	1989
X-ray microanalysis of urinary stones, a comparison with other methods. Scanning electron microscopy, 1985, Issue:Pt 3 Topics: Calcium Oxalate; Calcium Phosphates; Calcium Sulfate; Cystine; Electron Probe Microanalysis; Humans;	1985
Urolithiasis in Jordanian children. A report of 52 cases. British journal of urology, 1988, Volume: 61, Issue:6 Topics: Adolescent; Age Factors; Calcium Oxalate; Child; Child, Preschool; Female; Humans; Infant; Jordan; M	1988
Urolithiasis in childhood. Pediatric clinics of North America, 1987, Volume: 34, Issue:3 Topics: Acidosis, Renal Tubular; Adult; Calcium; Child; Child, Preschool; Diet; Female; Humans; Hyperoxaluri	1987
The hyperuricosuric calcium oxalate stone former. Mineral and electrolyte metabolism, 1987, Volume: 13, Issue:4 Topics: Calcium Oxalate; Humans; Syndrome; Uric Acid; Urinary Calculi	1987
Etiopathogenesis, clinical manifestations, and management of canine calcium oxalate urolithiasis. The Veterinary clinics of North America. Small animal practice, 1986, Volume: 16, Issue:1 Topics: Allopurinol; Animals; Benzothiadiazines; Calcium Oxalate; Cellulose; Citrates; Crystallization; Diur	1986
Etiopathogenesis of uric acid and ammonium urate uroliths in non-Dalmatian dogs. The Veterinary clinics of North America. Small animal practice, 1986, Volume: 16, Issue:1 Topics: Animals; Dog Diseases; Dogs; Quaternary Ammonium Compounds; Uric Acid; Urinary Calculi	1986
Pathophysiological aspects of stone disease. Contributions to nephrology, 1987, Volume: 55 Topics: Calcium; Diet; Humans; Hyperoxaluria; Uric Acid; Urinary Calculi	1987
Urinary tract stones. American family physician, 1985, Volume: 31, Issue:2 Topics: Calcinosis; Calcium; Cystine; Humans; Magnesium; Magnesium Compounds; Phosphates; Radiography; Struv	1985
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Calcium oxalate urolithiasis in the rat: is it a model for human stone disease? A review of recent literature. Scanning electron microscopy, 1985, Issue:Pt 2 Topics: Animals; Calcium Oxalate; Diet; Disease Models, Animal; Ethylene Glycols; Female; Foreign Bodies; Gl	1985
Urinary stones. Primary care, 1985, Volume: 12, Issue:4 Topics: Calcium; Crystallization; Cystine; Cystinuria; Humans; Kidney Calculi; Magnesium; Magnesium Compound	1985
Symposium on renal lithiasis. Medical evaluation of urolithiasis. Etiologic aspects and diagnostic evaluation. The Urologic clinics of North America, 1974, Volume: 1, Issue:2 Topics: Acidosis, Renal Tubular; Bacterial Infections; Citrates; Crystallization; Cystinuria; Diphosphates;	1974
[Physical, chemical and biological bases for the treatment and prevention of urolithiasis]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1973, May-15, Volume: 26, Issue:10 Topics: Acid-Base Equilibrium; Allopurinol; Diet Therapy; Humans; Postoperative Complications; Uric Acid; Ur	1973
Oxalate metabolism. 3. The American journal of clinical nutrition, 1973, Volume: 26, Issue:9 Topics: Age Factors; Aged; Calcium; Child; Child, Preschool; Female; Humans; Infant; Kidney Calculi; Male; N	1973
Symposium on renal lithiasis. The analysis of urinary calculi. The Urologic clinics of North America, 1974, Volume: 1, Issue:2 Topics: Apatites; Calcium; Calcium Carbonate; Calcium Phosphates; Crystallization; Cystine; Humans; Hydroxya	1974
[Metabolic factors associated with urolithiasis. Part II (author's transl)]. Przeglad lekarski, 1974, Volume: 31, Issue:12 Topics: Allopurinol; Bile Acids and Salts; Calcium; Diuretics; Humans; Hydrogen-Ion Concentration; Hyperpara	1974
[The formation of uric acid calculi seen from the view of the urologist]. Urologia internationalis, 1968, Volume: 23, Issue:5 Topics: Aged; Female; Humans; Uric Acid; Urinary Calculi	1968
[Urinary concretions]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Nov-15, Volume: 90, Issue:22 Topics: Calcium; Cystine; Diet Therapy; Humans; Oxalates; Phosphates; Sulfates; Uric Acid; Urinary Calculi	1970
[Features of uric acid metabolism in leukemia]. Sovetskaia meditsina, 1970, Volume: 33, Issue:7 Topics: Acute Disease; Chronic Disease; Female; Humans; Leukemia; Male; Uremia; Uric Acid; Urinary Calculi	1970
Current status of canine urolithiasis. Journal of the American Veterinary Medical Association, 1971, Feb-01, Volume: 158, Issue:3 Topics: Administration, Oral; Age Factors; Allopurinol; Animals; Anti-Bacterial Agents; Bicarbonates; Cystin	1971
[Uric acid calculosis]. Deutsches medizinisches Journal, 1970, Apr-20, Volume: 21, Issue:8 Topics: Adolescent; Adult; Aged; Alkalies; Allopurinol; Chemistry Techniques, Analytical; Child; Child, Pres	1970
[Gout. Clinical aspects, pathogenesis, current treatment]. Les Cahiers de medecine, 1971, Apr-30, Volume: 12, Issue:6 Topics: Calcinosis; Colchicine; Diagnosis, Differential; Diet Therapy; Female; Gout; Humans; Joint Diseases;	1971
Some problems concerning urinary calculi. The Practitioner, 1971, Volume: 207, Issue:241 Topics: Analgesics; Calcium; Cystinuria; Diet Therapy; Female; Humans; Hypercalcemia; Hyperparathyroidism; M	1971
Allopurinol. A review. Le Journal medical libanais. The Lebanese medical journal, 1971, Volume: 24, Issue:5 Topics: Adult; Allopurinol; Child; Drug Hypersensitivity; Drug Interactions; Gout; Humans; Iron; Kidney Dise	1971

Article	Year
Effect of Two Different Dietary Weight Loss Strategies on Risk Factors for Urinary Stone Formation and Cardiometabolic Risk Profile in Overweight Women. Nutrients, 2022, Nov-27, Volume: 14, Issue:23 Topics: Diet; Female; Humans; Kidney Calculi; Overweight; Risk Factors; Uric Acid; Urinary Calculi; Urolithi	2022
Effect of Two Different Dietary Weight Loss Strategies on Risk Factors for Urinary Stone Formation and Cardiometabolic Risk Profile in Overweight Women. Nutrients, 2022, Nov-27, Volume: 14, Issue:23 Topics: Diet; Female; Humans; Kidney Calculi; Overweight; Risk Factors; Uric Acid; Urinary Calculi; Urolithi	2022
Effect of Two Different Dietary Weight Loss Strategies on Risk Factors for Urinary Stone Formation and Cardiometabolic Risk Profile in Overweight Women. Nutrients, 2022, Nov-27, Volume: 14, Issue:23 Topics: Diet; Female; Humans; Kidney Calculi; Overweight; Risk Factors; Uric Acid; Urinary Calculi; Urolithi	2022
Effect of Two Different Dietary Weight Loss Strategies on Risk Factors for Urinary Stone Formation and Cardiometabolic Risk Profile in Overweight Women. Nutrients, 2022, Nov-27, Volume: 14, Issue:23 Topics: Diet; Female; Humans; Kidney Calculi; Overweight; Risk Factors; Uric Acid; Urinary Calculi; Urolithi	2022
[Features of encrustation of ureteral stents in patients with calcium oxalate and urinary acid stones]. Urologiia (Moscow, Russia : 1999), 2023, Issue:2 Topics: Calcium Oxalate; Humans; Nephrolithiasis; Stents; Ureter; Ureteral Calculi; Ureteroscopy; Uric Acid;	2023
The influence of serum uric acid on renal function in patients with calcium or uric acid stone: A population-based analysis. PloS one, 2017, Volume: 12, Issue:7 Topics: Aged; Calcium Phosphates; Female; Humans; Kidney; Male; Middle Aged; Uric Acid; Urinary Calculi	2017
Property changes of urinary nanocrystallites and urine of uric acid stone formers after taking potassium citrate. Materials science & engineering. C, Materials for biological applications, 2013, Volume: 33, Issue:7 Topics: Adult; Aged; Case-Control Studies; Citric Acid; Female; Glycosaminoglycans; Humans; Hydrogen-Ion Con	2013
Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones. Clinical journal of the American Society of Nephrology : CJASN, 2013, Volume: 8, Issue:11 Topics: Adult; Allopurinol; Biomarkers; Calcium Oxalate; Double-Blind Method; Enzyme Inhibitors; Febuxostat;	2013
The effect of a vegetarian and different omnivorous diets on urinary risk factors for uric acid stone formation. European journal of nutrition, 2003, Volume: 42, Issue:6 Topics: Adult; Cross-Over Studies; Crystallization; Diet; Diet, Vegetarian; Dietary Proteins; Drinking; Huma	2003
Changes in urinary parameters after oral administration of potassium-sodium citrate and magnesium oxide to prevent urolithiasis. Urology, 2004, Volume: 63, Issue:1 Topics: Administration, Oral; Adult; Calcium; Calcium Oxalate; Citrates; Creatinine; Drug Synergism; Drug Th	2004
Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. Urological research, 2004, Volume: 32, Issue:5 Topics: Adult; Brazil; Calcium; Citric Acid; Female; Freeze Drying; Humans; Magnesium; Male; Middle Aged; Ox	2004
Stone forming risk of calcium citrate supplementation in healthy postmenopausal women. The Journal of urology, 2004, Volume: 172, Issue:3 Topics: Aged; Calcium; Calcium Citrate; Calcium Phosphates; Citric Acid; Dietary Supplements; Drug Therapy,	2004
Effect of indapamide on urinary calcium excretion in patients with and without urinary stone disease. The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6 Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Metabolism Disorders; Creatinine; D	2005
Effect of cranberry juice consumption on urinary stone risk factors. The Journal of urology, 2005, Volume: 174, Issue:2 Topics: Acid-Base Equilibrium; Adult; Female; Food; Humans; Male; Phosphorus; Risk Factors; Uric Acid; Urina	2005
Results of a prospective trial to compare normal urine supersaturation in children and adults. The Journal of urology, 2005, Volume: 174, Issue:4 Pt 2 Topics: Adolescent; Adult; Calcium Oxalate; Calcium Phosphates; Child; Child, Preschool; Citric Acid; Female	2005
Clinical study on the effect of mineral waters containing bicarbonate on the risk of urinary stone formation in patients with multiple episodes of CaOx-urolithiasis. World journal of urology, 2007, Volume: 25, Issue:3 Topics: Adult; Bicarbonates; Calcium Oxalate; Calcium Phosphates; Cross-Over Studies; Double-Blind Method; F	2007
Effect of dietary control of urinary uric acid excretion in calcium oxalate stone formers and non-stone-forming controls. Journal of endourology, 2007, Volume: 21, Issue:2 Topics: Adult; Calcium Oxalate; Case-Control Studies; Diet; Female; Humans; Male; Uric Acid; Urinary Calculi	2007
[Allopurinol in the treatment of gout and uric acid nephrolithiasis]. Deutsche medizinische Wochenschrift (1946), 1967, Apr-04, Volume: 92, Issue:14 Topics: Allopurinol; Enzyme Therapy; Gout; Humans; Kidney Calculi; Uric Acid; Urinary Calculi; Xanthine Oxid	1967
Placebo versus allopurinol for recurrent urinary calculi. Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 20 Topics: Allopurinol; Clinical Trials as Topic; Humans; Hydrogen-Ion Concentration; Uric Acid; Urinary Calcul	1983
Thiazide prophylaxis of urolithiasis. A double-blind study in general practice. Acta medica Scandinavica, 1984, Volume: 215, Issue:4 Topics: Adolescent; Adult; Aged; Calcium; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up S	1984
Metabolic effects of thiazide versus placebo in patients under long-term treatment for recurrent urolithiasis. Scandinavian journal of urology and nephrology, 1984, Volume: 18, Issue:2 Topics: Adolescent; Adult; Aged; Calcium; Female; Humans; Hydrochlorothiazide; Magnesium; Male; Middle Aged;	1984
[Prevention of urinary calculi by means of a benzbromarone-citrate combination]. Fortschritte der Medizin, 1980, Nov-27, Volume: 98, Issue:44 Topics: Adult; Aged; Benzbromarone; Benzofurans; Circadian Rhythm; Citrates; Drug Combinations; Humans; Hydr	1980
Influence of four diets containing approximately 11% protein (dry weight) on uric acid, sodium urate, and ammonium urate urine activity product ratios of healthy beagles. American journal of veterinary research, 1995, Volume: 56, Issue:1 Topics: Analysis of Variance; Animals; Dietary Proteins; Dog Diseases; Dogs; Female; Uric Acid; Urinary Calc	1995
[Cause of hematuria in children with special consideration of urolithiasis. Personal observations]. Przeglad lekarski, 1997, Volume: 54, Issue:7-8 Topics: Adolescent; Calcium; Child; Child, Preschool; Crystallization; Hematuria; Humans; Uric Acid; Urinary	1997
Urinary excretion substances in patients with cystic fibrosis: risk of urolithiasis? Pediatric nephrology (Berlin, Germany), 1998, Volume: 12, Issue:4 Topics: Adolescent; Adult; Calcium Oxalate; Calcium Phosphates; Child; Child, Preschool; Cystic Fibrosis; Fe	1998
Uric acid-binding proteins in calcium oxalate stone formers and their effect on calcium oxalate crystallization. BJU international, 1999, Volume: 83, Issue:9 Topics: Calcium Oxalate; Carrier Proteins; Crystallization; Humans; Uric Acid; Urinary Calculi	1999
Effect of grapefruit juice on urinary lithogenicity. The Journal of urology, 2001, Volume: 166, Issue:1 Topics: Adult; Beverages; Calcium Oxalate; Calcium Phosphates; Citrus; Female; Humans; Hyperoxaluria; Male;	2001
Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. Journal of endourology, 2002, Volume: 16, Issue:3 Topics: Adolescent; Adult; Calcium; Calcium Oxalate; Citric Acid; Diuretics; Female; Follow-Up Studies; Huma	2002
Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. Journal of endourology, 2002, Volume: 16, Issue:3 Topics: Adolescent; Adult; Calcium; Calcium Oxalate; Citric Acid; Diuretics; Female; Follow-Up Studies; Huma	2002
Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. Journal of endourology, 2002, Volume: 16, Issue:3 Topics: Adolescent; Adult; Calcium; Calcium Oxalate; Citric Acid; Diuretics; Female; Follow-Up Studies; Huma	2002
Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. Journal of endourology, 2002, Volume: 16, Issue:3 Topics: Adolescent; Adult; Calcium; Calcium Oxalate; Citric Acid; Diuretics; Female; Follow-Up Studies; Huma	2002
[Antirelapse action of the flowers of the blue cornflower in urolithiasis]. Zhurnal eksperimental'noi i klinicheskoi meditsiny, 1978, Volume: 18, Issue:6 Topics: Adult; Calcium; Clinical Trials as Topic; Diuresis; Drug Evaluation; Female; Humans; Male; Middle Ag	1978
[Role of in situ alkalinization in the treatment of obstructive uric acid lithiasis]. Annales d'urologie, 1992, Volume: 26, Issue:6-7 Topics: Aged; Bicarbonates; Humans; Hydrogen-Ion Concentration; Middle Aged; Nephrostomy, Percutaneous; Radi	1992
Thiazide treatment for calcium urolithiasis in patients with idiopathic hypercalciuria. British journal of urology, 1992, Volume: 69, Issue:6 Topics: Adult; Calcium; Female; Humans; Male; Middle Aged; Trichlormethiazide; Uric Acid; Urinary Calculi	1992
Allopurinol and thiazide effects on new urinary stone formed after discontinued therapy in patients with urinary stones. Urology, 1990, Volume: 36, Issue:4 Topics: Allopurinol; Calcium; Calcium Oxalate; Calcium Phosphates; Citrates; Drug Therapy, Combination; Huma	1990
Proceedings: Urinary excretion of oxalate, calcium, magnesium, and uric acid in inflammatory bowel disease and relationship to urolithiasis. Gut, 1973, Volume: 14, Issue:10 Topics: Calcium; Crohn Disease; Humans; Magnesium; Oxalates; Uric Acid; Urinary Calculi	1973

uric acid and Urinary Calculi

Research Excerpts

Research

Studies (1,127)

Authors

Clinical Trials (9)

Trial Overview

Trial Outcomes

Percent Change From Baseline to Month 6 in 24-hour Urine Uric Acid (uUA) Excretion

Percent Change From Baseline to Month 6 in the In-plane Diameter of the Largest Calcium Oxalate (CaOx) Stone

Change From Baseline to Month 6 in 24-hour Measured Creatinine Clearance

Change From Baseline to Month 6 in the Number of Calcium Oxalate Stones

Incidence of Postoperative Side Effects

Post Operative Pain Scale

Post Operative Pain Score

Post Operative Pain Score

Post-operative Opioid Requirements

Reviews

Trials

Other Studies

Authors	Studies
Mercurio, M	1
Izzo, F	1
Gatta, GD	1
Salzano, L	1
Lotrecchiano, G	1
Saldutto, P	1
Germinario, C	1
Grifa, C	1
Varricchio, E	1
Carafa, A	1
Di Meo, MC	1
Langella, A	1
Miyauchi, T	4
Terashita, M	1
Ogata, M	1
Murata, M	1
Osako, K	1
Imai, N	1
Sakurai, Y	1
Sasaki, H	1
Ohashi, Y	2
Ichida, K	13
Shibagaki, Y	1
Yazawa, M	1
Nitkin, DM	1
Juraha, TM	1
Gres, AA	1
Gres, NA	1
Solovey, OM	1
Ban, H	1
Miura, K	1
Tomoeda, R	1
Hirai, K	1
Hattori, M	1
Koto, R	1
Sato, I	1
Kuwabara, M	6
Seki, T	1
Kawakami, K	1
Wen, W	1