Page last updated: 2024-10-20

uric acid and Thromboembolism

uric acid has been researched along with Thromboembolism in 13 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Research Excerpts

ExcerptRelevanceReference
"Uric acid is a natural antioxidant that protects the brain in a model of transient focal ischemia in rats."5.34Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. ( Amaro, S; Chamorro, A; Planas, AM; Romanos, E, 2007)
" Although hyperuricemia is a risk factor for cardiovascular diseases, the relationship between serum uric acid (UA) levels and thromboembolic risk has not been fully elucidated in patients with AF."5.19Hyperuricemia and transesophageal echocardiographic thromboembolic risk in patients with atrial fibrillation at clinically low-intermediate risk. ( Fukuda, N; Hirai, T; Inoue, H; Nakagawa, K; Nozawa, T; Numa, S; Ohara, K, 2014)
"Uric acid is a natural antioxidant that protects the brain in a model of transient focal ischemia in rats."1.34Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. ( Amaro, S; Chamorro, A; Planas, AM; Romanos, E, 2007)
"Twenty-six transfusions (5."1.33Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome. A study in 453 consecutive pregnancies. ( Codaccioni, X; Coudoux, E; Deruelle, P; Ego, A; Houfflin-Debarge, V; Subtil, D, 2006)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Cicero, AFG1
Fogacci, F1
Borghi, C1
Numa, S1
Hirai, T1
Nakagawa, K1
Ohara, K1
Fukuda, N1
Nozawa, T1
Inoue, H1
Fricker, J1
Deruelle, P1
Coudoux, E1
Ego, A1
Houfflin-Debarge, V1
Codaccioni, X1
Subtil, D1
Romanos, E1
Planas, AM1
Amaro, S1
Chamorro, A1
Steele, P1
Rainwater, J1
Abbott, RD1
Curb, JD1
Rodriguez, BL1
Sharp, DS1
Burchfiel, CM1
Yano, K1
Mertz, DP1
Zöller, H1
Gross, W1
Rieke, K1
Khalifa, P1
Sereni, D1
Boissonnas, A1
Cremer, GA1
Laroche, C1
Kramer, HJ1
Krück, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Double Blind Study Assessing the Clinical Efficacy of Combined Treatment With Uric Acid and rtPA Administered Intravenously in Acute Ischemic Stroke Patients Within the First 4.5 Hours of Symptoms Onset[NCT00860366]Phase 2/Phase 3421 participants (Actual)Interventional2011-06-30Completed
[NCT00005123]0 participants Observational1965-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for uric acid and Thromboembolism

ArticleYear
[Significance of physical activity in the prevention of degenerative heart and vascular diseases?].
    Deutsche medizinische Wochenschrift (1946), 1976, Feb-06, Volume: 101, Issue:6

    Topics: Adult; Age Factors; Arteriosclerosis; Body Weight; Cerebral Hemorrhage; Cerebrovascular Disorders; C

1976
[Pharmacological bases of diuretic therapy. 2].
    Medizinische Klinik, 1974, Jan-18, Volume: 69, Issue:3

    Topics: Acidosis; Alkalosis; Digitalis Glycosides; Diuretics; Drug Synergism; Edema; Gastrointestinal Hemorr

1974

Trials

1 trial available for uric acid and Thromboembolism

ArticleYear
Hyperuricemia and transesophageal echocardiographic thromboembolic risk in patients with atrial fibrillation at clinically low-intermediate risk.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:7

    Topics: Adult; Aged; Atrial Fibrillation; Echocardiography, Transesophageal; Female; Humans; Hyperuricemia;

2014

Other Studies

10 other studies available for uric acid and Thromboembolism

ArticleYear
Uric acid and thrombotic risk: an emerging link.
    Internal and emergency medicine, 2020, Volume: 15, Issue:7

    Topics: Cardiomyopathy, Hypertrophic; Humans; Hyperuricemia; Risk Factors; Thromboembolism; Uric Acid

2020
50th ASH Annual Meeting.
    The Lancet. Oncology, 2009, Volume: 10, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Humans; Lenalidomide; Leukemia, Lymp

2009
Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome. A study in 453 consecutive pregnancies.
    European journal of obstetrics, gynecology, and reproductive biology, 2006, Mar-01, Volume: 125, Issue:1

    Topics: Abscess; Adult; Ascites; Cesarean Section; Creatinine; Disseminated Intravascular Coagulation; Femal

2006
Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:1

    Topics: Animals; Brain Damage, Chronic; Brain Edema; Humans; Infarction, Middle Cerebral Artery; Male; Neuro

2007
Favorable effect of sulfinpyrazone on thromboembolism in patients with rheumatic heart disease.
    Circulation, 1980, Volume: 62, Issue:3

    Topics: Atrial Fibrillation; Blood Coagulation; Blood Platelets; Cell Survival; Heart Valve Prosthesis; Huma

1980
Effect of dietary calcium and milk consumption on risk of thromboembolic stroke in older middle-aged men. The Honolulu Heart Program.
    Stroke, 1996, Volume: 27, Issue:5

    Topics: Age Factors; Aged; Alcohol Drinking; Animals; Blood Glucose; Body Mass Index; Calcium, Dietary; Chol

1996
[New specialties, registered in Austria. Anturane 200 mg dragees, regulator of platelet function].
    Wiener klinische Wochenschrift, 1979, Nov-23, Volume: 91, Issue:22

    Topics: Aspirin; Austria; Drug Interactions; Drug Tolerance; Pharmacopoeias as Topic; Platelet Aggregation;

1979
Clotting properties in diverse valve prostheses.
    Zeitschrift fur Kardiologie, 1986, Volume: 75 Suppl 2

    Topics: Bioprosthesis; Blood Coagulation Tests; Female; Heart Valve Diseases; Heart Valve Prosthesis; Hemoly

1986
[Attacks of gout and thromboembolic disease: role of heparin therapy].
    Annales de medecine interne, 1985, Volume: 136, Issue:7

    Topics: Acute Disease; Aged; Arthritis; Female; Gout; Heparin; Humans; Male; Middle Aged; Thromboembolism; U

1985
Hypertension, hyperuricemia and iatrogenic disease.
    The American journal of medicine, 1970, Volume: 49, Issue:2

    Topics: Aged; Allopurinol; Aortic Diseases; Arteriosclerosis; Brain; Catheterization; Chlorothiazide; Diagno

1970