Page last updated: 2024-10-20

uric acid and Spondylitis, Ankylosing

uric acid has been researched along with Spondylitis, Ankylosing in 30 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Spondylitis, Ankylosing: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

Research Excerpts

ExcerptRelevanceReference
"BACKGROUND This study was to investigate the correlation between osteoporosis and serum uric acid in ankylosing spondylitis (AS) patients, and to further identify potential factors that might be associated with osteoporosis in AS patients."7.91Serum Uric Acid Shows Inverted "U" Type Correlation with Osteoporosis in Chinese Ankylosing Spondylitis Patients: A Retrospective Study. ( Chen, YT; Chen, Z; Lin, C; Liu, X; Song, P; Wu, Y; Xu, Q; Yang, P; Yang, Y, 2019)
"BACKGROUND This study was to investigate the correlation between osteoporosis and serum uric acid in ankylosing spondylitis (AS) patients, and to further identify potential factors that might be associated with osteoporosis in AS patients."3.91Serum Uric Acid Shows Inverted "U" Type Correlation with Osteoporosis in Chinese Ankylosing Spondylitis Patients: A Retrospective Study. ( Chen, YT; Chen, Z; Lin, C; Liu, X; Song, P; Wu, Y; Xu, Q; Yang, P; Yang, Y, 2019)
"Comparative analysis with obesity, type 2 diabetes, ankylosing spondylitis and rheumatoid arthritis indicated that gout metagenomes were more similar to those of autoimmune than metabolic diseases."1.62Metagenomic analysis revealed the potential role of gut microbiome in gout. ( Bai, X; Chen, X; Chu, Y; Ding, F; Fang, X; Gao, Q; He, X; Huang, Q; Huang, R; Huang, Y; Jiang, Y; Li, J; Liang, L; Sun, S; Wang, M; Wang, P; Wang, Z; Wei, X; Wu, J; Wu, X; Xie, X; Yang, J; Yue, Z; Zhang, Y; Zhao, Y; Zhou, C, 2021)
"Sixty-one patients with gout, 30 with ankylosing spondylitis and 30 with rheumatoid arthritis were included in the study."1.42[Value of dual-energy computed tomography in the diagnosis of gouty arthritis]. ( Cai, X; Ren, J; Wu, H; Zhou, Y; Zhu, L, 2015)
"Uric acid (UA) has antiosteoporotic effects in postmenopausal women."1.42Low levels of serum uric Acid increase the risk of low bone mineral density in young male patients with ankylosing spondylitis. ( Hong, YS; Ju, JH; Kang, KY; Park, SH, 2015)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199013 (43.33)18.7374
1990's2 (6.67)18.2507
2000's1 (3.33)29.6817
2010's10 (33.33)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Cai, M1
Liu, W3
Wu, Y3
Zheng, Q1
Liu, D1
Shi, G3
Lai, Y1
Zhang, Y2
Lei, Z1
Huang, Y3
Ni, T1
He, P1
Li, X1
Xu, C1
Xia, J1
Wang, M2
Chen, Z1
Yang, P1
Liu, X1
Yang, Y1
Song, P1
Chen, YT1
Lin, C1
Xu, Q1
Pietsch, DEW1
Kubler, P1
Robinson, PC1
Chu, Y1
Sun, S1
Gao, Q1
Xie, X1
Wang, P1
Li, J1
Liang, L1
He, X1
Jiang, Y1
Yang, J1
Chen, X2
Zhou, C1
Zhao, Y1
Ding, F1
Wu, X1
Bai, X1
Wu, J1
Wei, X1
Yue, Z1
Fang, X1
Huang, Q1
Wang, Z1
Huang, R1
Huang, H1
Yu, B1
Lin, Q1
Chen, L1
Chen, J2
Duan, L2
Zhang, G1
Wang, N1
Xue, Q1
Wangkaew, S1
Kasitanon, N1
Hongsongkiat, S1
Tanasombat, C1
Sukittawut, W1
Louthrenoo, W1
Ren, J1
Zhou, Y1
Wu, H1
Zhu, L1
Cai, X1
Kang, KY2
Hong, YS1
Park, SH1
Ju, JH2
Sigdel, KR1
Wang, Y1
Su, Q1
Zhang, YL1
Dogan, T1
Agilli, M1
Lee, SH2
Lee, EJ1
Chung, SW1
Song, R1
Moon, JY1
Lim, SJ1
Lee, YA1
Hong, SJ1
Yang, HI1
THOMPSON, GR1
MARTEL, W1
RAKIC, MT1
HAYES, JT1
KELLGREN, JH1
FERNANDEZDELVALLADO, P1
GIJONBANOS, J1
BELTRANGUTIERREZ, J1
GARCIASORO, JM1
Justiniano, M1
Colmegna, I1
Cuchacovich, R1
Espinoza, LR1
Schattenkirchner, M1
Cutolo, M1
Accardo, S1
Cimmino, MA1
Rovida, S1
Sorgi, ML1
Quaratino, CP2
Rucci, C1
Ciaglia, P1
Zoppini, A2
Giacomello, A2
Blécourt, JJ1
Sorghi, ML1
Savini, F1
Bośmanský, K1
Ondrasík, M1
Solomon, L1
Ferguson, RH1
Worthington, JW1
Frank, O1
Tidl, G1
Franck, WA1
Bress, NM1
Singer, FR1
Krane, SM1
Bäumer, A1
Pircher, W1
Schickentanz, M1
Glass, HI1
Scott, JT1
Gilles, DC1
Arnot, RN1
Holloway, VP1
Ben Hameid, SS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders[NCT06092346]999 participants (Anticipated)Observational2024-01-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for uric acid and Spondylitis, Ankylosing

ArticleYear
Recent advances in rheumatic diseases: 1967 through 1969.
    Annals of internal medicine, 1970, Volume: 73, Issue:1

    Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Arthritis, Rheumatoid; Behcet Syndrome; Colla

1970

Other Studies

29 other studies available for uric acid and Spondylitis, Ankylosing

ArticleYear
The serum uric acid is longitudinally related to patients global assessment of disease activity in male patients with axial spondyloarthritis.
    BMC musculoskeletal disorders, 2022, Jul-27, Volume: 23, Issue:1

    Topics: Axial Spondyloarthritis; Cohort Studies; Humans; Male; Severity of Illness Index; Spondylarthritis;

2022
Association between serum uric acid concentration and radiographic axial spondylarthritis: a cross-sectional study of 202 patients.
    Chinese medical journal, 2023, 05-05, Volume: 136, Issue:9

    Topics: C-Reactive Protein; Cross-Sectional Studies; Humans; Spondylarthritis; Spondylitis, Ankylosing; Uric

2023
Serum Uric Acid Shows Inverted "U" Type Correlation with Osteoporosis in Chinese Ankylosing Spondylitis Patients: A Retrospective Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Dec-18, Volume: 25

    Topics: Adolescent; Adult; Antirheumatic Agents; Asian People; Blood Platelets; Blood Sedimentation; Bone De

2019
The effect of reducing systemic inflammation on serum urate.
    Rheumatology (Oxford, England), 2020, Oct-01, Volume: 59, Issue:10

    Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Sedimentation; C-Rea

2020
Metagenomic analysis revealed the potential role of gut microbiome in gout.
    NPJ biofilms and microbiomes, 2021, 08-09, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Arthritis; Bacteria; Butyrates; Diabetes Mellitus, Type 2; Dysbiosis; Fatty

2021
Serum apoprotein A1 levels are inversely associated with disease activity in gout: From a southern Chinese Han population.
    Medicine, 2017, Volume: 96, Issue:17

    Topics: Adult; Apolipoprotein A-I; Arthritis, Gouty; Arthritis, Rheumatoid; Asian People; Biomarkers; Blood

2017
Risk Factors of Renal Involvement Based on Different Manifestations in Patients with Ankylosing Spondylitis.
    Kidney & blood pressure research, 2018, Volume: 43, Issue:2

    Topics: Female; Hematuria; Humans; Immunoglobulin A; Kidney Diseases; Logistic Models; Male; Risk Factors; S

2018
A comparative study of serum and synovial fluid levels of uric acid between patients with gout and other arthritides.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arthritis; Arthritis, Gouty; Arthritis, Infectious; Arthritis, Rheum

2014
[Value of dual-energy computed tomography in the diagnosis of gouty arthritis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:3

    Topics: Arthritis, Gouty; Arthritis, Rheumatoid; Color; Diagnosis, Differential; Humans; Hyperuricemia; Spon

2015
Low levels of serum uric Acid increase the risk of low bone mineral density in young male patients with ankylosing spondylitis.
    The Journal of rheumatology, 2015, Volume: 42, Issue:6

    Topics: Adult; Age Factors; Bone Density; Confidence Intervals; Databases, Factual; Follow-Up Studies; Human

2015
High Level Serum Procalcitonin Associated Gouty Arthritis Susceptibility: From a Southern Chinese Han Population.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adult; Aged; Arthritis, Gouty; Arthritis, Rheumatoid; Asian People; Biomarkers; Blood Sedimentation;

2015
Assessment of Serum Uric Acid in Young Male Patients with Ankylosing Spondylitis.
    The Journal of rheumatology, 2016, Volume: 43, Issue:3

    Topics: Humans; Male; Osteoporosis; Spondylitis, Ankylosing; Uric Acid

2016
Drs. Kang and Ju reply.
    The Journal of rheumatology, 2016, Volume: 43, Issue:3

    Topics: Humans; Male; Osteoporosis; Spondylitis, Ankylosing; Uric Acid

2016
Renal involvement in ankylosing spondylitis: prevalence, pathology, response to TNF-a blocker.
    Rheumatology international, 2013, Volume: 33, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Biopsy; Chi-Square Distribution; Creatinine; Female; He

2013
ANKYLOSING SPONDYLITIS, HYPERURICEMIA, AND ANOMALIES OF THE LUMBOSACRAL JUNCTION. A FAMILY STUDY.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Blood Chemical Analysis; Genetics, Medical; Gout; Hyperuricemia; Lumbosacral Region; Research; Spine

1963
THE EPIDEMIOLOGY OF RHEUMATIC DISEASES.
    Annals of the rheumatic diseases, 1964, Volume: 23

    Topics: Arthritis; Arthritis, Rheumatoid; Blood; Colitis; Colitis, Ulcerative; Crohn Disease; Enteritis; Epi

1964
[ANKYLOSING SPONDYLITIS. ETIOLOGICAL CONSIDERATIONS AND CLINICAL ASPECTS].
    Revista clinica espanola, 1964, Apr-15, Volume: 93

    Topics: Arthritis; Arthritis, Rheumatoid; Blood Protein Electrophoresis; Blood Sedimentation; C-Reactive Pro

1964
Spondyloarthritis as a presentation of gouty arthritis.
    The Journal of rheumatology, 2007, Volume: 34, Issue:5

    Topics: Arthritis, Gouty; Colchicine; Diagnosis, Differential; Female; Gout Suppressants; Humans; Lumbar Ver

2007
[Pathogenetic mechanisms in joint diseases].
    Medizinische Klinik, 1981, May-08, Volume: 76, Issue:10

    Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Autoimmune Diseases; Chondrocalcinosis; Cryst

1981
Plasma fibronectin in psoriatic arthritis subgroups.
    Clinical rheumatology, 1984, Volume: 3, Issue:2

    Topics: Arthritis; Arthritis, Rheumatoid; C-Reactive Protein; Copper; Female; Fibronectins; Hemoglobinometry

1984
Differential diagnosis of main rheumatic diseases in man.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Glucose; Blood Sedimentation; Blood Urea Nitrogen

1994
[25 years of arthritis treatment in the province of Groningen].
    Nederlands tijdschrift voor geneeskunde, 1975, Jun-07, Volume: 119, Issue:23

    Topics: Adolescent; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Child; Child, Preschool; Female; Gout; Hu

1975
Gout and main rheumatic diseases in man.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adult; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Female; Gout; Humans; Male; Middle Ag

1991
[Uric acid levels of the serum of healthy persons and patients with various rheumatic diseases].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:4

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Gout; Humans; Male; Middle Aged; Osteoarthri

1987
Laboratory investigations in connective tissue disease.
    Modern trends in orthopaedics, 1972, Volume: 5

    Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Biopsy; Connective Tissue; Dermatomyositis; Diphosph

1972
[The prevalence of lipid metabolism disorders in rheumatological diseases].
    Wiener medizinische Wochenschrift (1946), 1974, Sep-14, Volume: 124, Issue:37

    Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Blood Glucose; Body Weight; Cholesterol; Diabetes M

1974
Rheumatic manifestations of Paget's disease of bone.
    The American journal of medicine, 1974, Volume: 56, Issue:5

    Topics: Adult; Aged; Alkaline Phosphatase; Arthritis; Arthritis, Rheumatoid; Female; Finger Joint; Gout; Hum

1974
[Comparative studies on serum uric acid and fatty acid ester levels in ankylosing spondylitis with and without inflammatory reaction].
    Klinische Wochenschrift, 1971, Nov-01, Volume: 49, Issue:21

    Topics: Blood Sedimentation; Esters; Fatty Acids; Female; Humans; Inflammation; Male; Spondylitis, Ankylosin

1971
The interpretation of radioactive uric acid turnover data.
    Strahlentherapie. Sonderbande, 1968, Volume: 67

    Topics: Arthritis, Rheumatoid; Biological Assay; Carbon Isotopes; Gout; Humans; Hypertension; Myocardial Inf

1968