uric acid has been researched along with Schizophrenia in 27 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The association between schizophrenia (SZ) and uric acid (UA) levels has been suggested for many years, but without solid evidence." | 9.05 | Uric acid levels in subjects with schizophrenia: A systematic review and meta-analysis. ( Chen, L; Chen, Y; He, Q; Lu, H; Wu, S; Yao, L; You, Y; Yu, L; Zhao, X; Zhou, X, 2020) |
| "This study examined the relationship between serum levels of uric acid and insulin resistance and metabolic syndrome in nondiabetic patients with schizophrenia." | 7.83 | Relationship between serum uric acid level and cardiometabolic risks in nondiabetic patients with schizophrenia. ( Cimpeanu, C; Fan, X; Harrington, A; Rajan, S; Song, X; Zalpuri, I, 2016) |
| "We tested the hypothesis that uric acid levels are higher in subjects with schizophrenia treated with clozapine than in healthy control and they correlate with anthropometric measurements, laboratory tests and results of bioimpedance analysis of body composition." | 7.81 | Uric acid levels in patients with schizophrenia on clozapine monotherapy. ( Kłoszewska, I; Wysokiński, A, 2015) |
| "Uric acid (UA) has been frequently reported to be associated with MetS in the general population." | 5.38 | The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder. ( Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Lu, ML; Tsai, CJ, 2012) |
| "The association between schizophrenia (SZ) and uric acid (UA) levels has been suggested for many years, but without solid evidence." | 5.05 | Uric acid levels in subjects with schizophrenia: A systematic review and meta-analysis. ( Chen, L; Chen, Y; He, Q; Lu, H; Wu, S; Yao, L; You, Y; Yu, L; Zhao, X; Zhou, X, 2020) |
| " In the stable phase, schizophrenia patients had higher uric acid (p = 0." | 3.91 | A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia. ( Andreassen, OA; Bentsen, H; Refsum, H; Solberg, DK, 2019) |
| "This study examined the relationship between serum levels of uric acid and insulin resistance and metabolic syndrome in nondiabetic patients with schizophrenia." | 3.83 | Relationship between serum uric acid level and cardiometabolic risks in nondiabetic patients with schizophrenia. ( Cimpeanu, C; Fan, X; Harrington, A; Rajan, S; Song, X; Zalpuri, I, 2016) |
| "We tested the hypothesis that uric acid levels are higher in subjects with schizophrenia treated with clozapine than in healthy control and they correlate with anthropometric measurements, laboratory tests and results of bioimpedance analysis of body composition." | 3.81 | Uric acid levels in patients with schizophrenia on clozapine monotherapy. ( Kłoszewska, I; Wysokiński, A, 2015) |
| "Copeptin was significantly higher while uric acid, potassium and sodium levels were significantly lower in patients with schizophrenia compared with controls." | 3.80 | Serum copeptin and its diagnostic performance in schizophrenia. ( Akinladel, KS; Ampitan, AB; Fagbomedo, FO; Makanjuola, VA; Rahamon, SK, 2014) |
| "Altered uric acid regulation that resembles SIADH is present in patients with polydipsia-hyponatremia syndrome." | 3.69 | Hypouricemia in chronic schizophrenic patients with polydipsia and hyponatremia. ( Amagai, I; Hagimoto, H; Hanihara, T; Makimoto, Y, 1997) |
| "Uric acid (UA) has been frequently reported to be associated with MetS in the general population." | 1.38 | The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder. ( Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Lu, ML; Tsai, CJ, 2012) |
| "The bilirubin level was significantly lower in the negative subgroup of the patient group." | 1.32 | Decreased plasma antioxidants in schizophrenia. ( Kim, JJ; Lee, C; Lee, CU; Lee, SJ; Pae, CU; Paik, IH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (48.15) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Z | 1 |
| Wen, T | 1 |
| Wang, Y | 1 |
| Kan, W | 1 |
| Xun, G | 1 |
| He, Q | 1 |
| You, Y | 1 |
| Yu, L | 1 |
| Yao, L | 1 |
| Lu, H | 1 |
| Zhou, X | 1 |
| Wu, S | 1 |
| Chen, L | 1 |
| Chen, Y | 1 |
| Zhao, X | 1 |
| Solberg, DK | 1 |
| Refsum, H | 1 |
| Andreassen, OA | 1 |
| Bentsen, H | 1 |
| Wysokiński, A | 1 |
| Kłoszewska, I | 1 |
| Akinladel, KS | 1 |
| Fagbomedo, FO | 1 |
| Rahamon, SK | 1 |
| Makanjuola, VA | 1 |
| Ampitan, AB | 1 |
| Rajan, S | 1 |
| Zalpuri, I | 1 |
| Harrington, A | 1 |
| Cimpeanu, C | 1 |
| Song, X | 1 |
| Fan, X | 1 |
| Yao, JK | 3 |
| Dougherty, GG | 1 |
| Reddy, RD | 1 |
| Keshavan, MS | 1 |
| Montrose, DM | 1 |
| Matson, WR | 1 |
| McEvoy, J | 1 |
| Kaddurah-Daouk, R | 1 |
| Xuan, J | 1 |
| Pan, G | 1 |
| Qiu, Y | 1 |
| Yang, L | 1 |
| Su, M | 1 |
| Liu, Y | 1 |
| Chen, J | 1 |
| Feng, G | 1 |
| Fang, Y | 1 |
| Jia, W | 1 |
| Xing, Q | 1 |
| He, L | 1 |
| Chiu, CC | 1 |
| Chen, CH | 1 |
| Huang, MC | 1 |
| Chen, PY | 1 |
| Tsai, CJ | 1 |
| Lu, ML | 1 |
| Reddy, R | 2 |
| Keshavan, M | 1 |
| Pae, CU | 1 |
| Paik, IH | 1 |
| Lee, C | 1 |
| Lee, SJ | 1 |
| Kim, JJ | 1 |
| Lee, CU | 1 |
| Hanihara, T | 1 |
| Amagai, I | 1 |
| Hagimoto, H | 1 |
| Makimoto, Y | 1 |
| van Kammen, DP | 1 |
| Flemenbaum, A | 2 |
| Anderson, RP | 1 |
| Brooks, SC | 1 |
| Linn, JJ | 1 |
| Disney, N | 1 |
| Flemenbaum, E | 1 |
| Degrell, I | 1 |
| Nagy, E | 1 |
| Shalev, A | 1 |
| Hermesh, H | 1 |
| Munitz, H | 1 |
| Lis, AW | 1 |
| Bijan, R | 1 |
| Lis, EW | 1 |
| De Hackbeil, KF | 1 |
| Pfeiffer, CC | 1 |
| Iliev, V | 1 |
| Goldstein, L | 1 |
| Jenney, EH | 1 |
| Schultz, R | 1 |
| Woodrow, KM | 1 |
| Coleman, M | 1 |
| Carlsson, C | 1 |
| Dencker, SJ | 1 |
| Rosenbaum, CP | 1 |
| Mosher, LR | 1 |
| Shopsin, B | 1 |
| Kim, SS | 1 |
| Gershon, S | 1 |
| Gerard, RW | 1 |
4 reviews available for uric acid and Schizophrenia
| Article | Year |
|---|---|
Uric acid levels in subjects with schizophrenia: A systematic review and meta-analysis.
Topics: Antipsychotic Agents; Biomarkers; Case-Control Studies; Humans; Oxidation-Reduction; Oxidative Stres | 2020 |
Gilles de la Tourette's disease--a review.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Corpus Striatum; Diagnosis, Differential; Female; | 1974 |
Metabolic, physiological, anatomic and genetic studies in the schizophrenias: a review and analysis.
Topics: Adrenal Cortex Hormones; Blood Proteins; Brain; Creatinine; Diseases in Twins; Epinephrine; Fatty Ac | 1968 |
Nicotinic acid side effects and toxicity: a review.
Topics: Adult; Age Factors; Animals; Anxiety; Arteriosclerosis; Carbohydrate Metabolism; Digestive System; D | 1970 |
3 trials available for uric acid and Schizophrenia
| Article | Year |
|---|---|
The hypouricemic effect of chlorprothixene.
Topics: Administration, Oral; Adult; Aged; Chlorprothixene; Clinical Trials as Topic; Creatinine; Drug Thera | 1987 |
A crossover study of allopurinol administration to a schizophrenic child.
Topics: Administration, Oral; Allopurinol; Child; Child Behavior Disorders; Clinical Trials as Topic; Diet T | 1974 |
A controlled study of lithium vs. chlorpromazine in acute schizophrenics.
Topics: Acute Disease; Adult; Chlorpromazine; Clinical Trials as Topic; Constipation; Female; Humans; Leukoc | 1971 |
20 other studies available for uric acid and Schizophrenia
| Article | Year |
|---|---|
Peripheral non-enzymatic antioxidants in patients with schizophrenia: a case-control study.
Topics: Adult; Albumins; Antioxidants; Bilirubin; Case-Control Studies; Female; Humans; Male; Schizophrenia; | 2020 |
A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia.
Topics: Adult; alpha-Tocopherol; Antioxidants; Bilirubin; Biomarkers; Fatty Acids, Unsaturated; Female; Foll | 2019 |
Uric acid levels in patients with schizophrenia on clozapine monotherapy.
Topics: Adult; Anthropometry; Cardiovascular Diseases; Case-Control Studies; Clozapine; Female; Humans; Insu | 2015 |
Serum copeptin and its diagnostic performance in schizophrenia.
Topics: Adult; Area Under Curve; Female; Glycopeptides; Humans; International Classification of Diseases; Ma | 2014 |
Relationship between serum uric acid level and cardiometabolic risks in nondiabetic patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cross-Sectional Stu | 2016 |
Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Diet; Female; Guanosine; Homeostasis; | 2010 |
Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.
Topics: Adult; Biomarkers; Case-Control Studies; Citric Acid; Energy Metabolism; Female; Gas Chromatography- | 2011 |
The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder.
Topics: Adult; Cholesterol, HDL; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertriglyceridemia | 2012 |
Reduced plasma antioxidants in first-episode patients with schizophrenia.
Topics: Adult; Albumins; Antioxidants; Bilirubin; Cell Membrane; Chronic Disease; Diagnostic and Statistical | 2003 |
Decreased plasma antioxidants in schizophrenia.
Topics: Adult; Antioxidants; Antipsychotic Agents; Bilirubin; Case-Control Studies; Female; Humans; Male; Ri | 2004 |
Hypouricemia in chronic schizophrenic patients with polydipsia and hyponatremia.
Topics: Adult; Drinking; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Osmolar Concen | 1997 |
Reduced level of plasma antioxidant uric acid in schizophrenia.
Topics: Adult; Antioxidants; Antipsychotic Agents; Cotinine; Haloperidol; Humans; Male; Schizophrenia; Smoki | 1998 |
Field dependence and blood cholesterol: an expansion.
Topics: Adolescent; Adult; Affective Symptoms; Age Factors; Aged; Body Height; Body Weight; Cholesterol; Fem | 1978 |
Serotonin, folic acid, and uric acid metabolism in the diagnosis of neuropsychiatric disorders.
Topics: Adolescent; Adult; Bipolar Disorder; Brain; Carbolines; Female; Folic Acid; Hallucinations; Humans; | 1978 |
Field dependence, blood uric acid and cholesterol.
Topics: Adolescent; Adult; Affective Symptoms; Aged; Cholesterol; Female; Field Dependence-Independence; Hum | 1975 |
Concentration gradients for HVA, 5-HIAA, ascorbic acid, and uric acid in cerebrospinal fluid.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Ascorbic Acid; Brain; Dementia; Female; Homovanillic Acid; H | 1990 |
Ultraviolet-absorbing urinary components of mentally retarded children and schizophrenic adults.
Topics: Adolescent; Adult; Autoanalysis; Child; Chromatography, Ion Exchange; Chromatography, Paper; Down Sy | 1968 |
Blood histamine, polyamines and the schizophrenias. Computer correlations of the low and high blood histamine types.
Topics: Computers; Diagnosis, Computer-Assisted; Electroencephalography; Female; Histamine; Humans; Male; MM | 1970 |
Cerebrospinal uric acid in alcoholics.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Alcoholism; Humans; Male; Middle Aged; Schizophrenia; Spectr | 1973 |
The nosology of schizophrenia: a co-operative study.
Topics: Adaptation, Ocular; Adolescent; Adult; Anthropometry; Anxiety; Blood Pressure; Child Development; Cr | 1964 |