uric acid has been researched along with Pulmonary Fibrosis in 8 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperuricemia and gout are known to occur in patients receiving diuretic therapy." | 2.40 | Finger pad tophi. ( Chopra, KF; Grossman, ME; Schneiderman, P, 1999) |
| "The molecular mechanisms by which lung injury triggers IL-1beta production, inflammation, and fibrosis remain poorly understood." | 1.35 | Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. ( Charron, S; Couillin, I; Fick, L; Gasse, P; Girre, S; Lagente, V; Pétrilli, V; Quesniaux, VF; Riteau, N; Ryffel, B; Tschopp, J, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, C | 1 |
| He, L | 1 |
| Zhang, J | 2 |
| Ma, H | 1 |
| Yuan, X | 1 |
| Hu, G | 1 |
| Tao, L | 1 |
| Meng, J | 1 |
| Markart, P | 1 |
| Luboeinski, T | 1 |
| Korfei, M | 1 |
| Schmidt, R | 1 |
| Wygrecka, M | 1 |
| Mahavadi, P | 1 |
| Mayer, K | 1 |
| Wilhelm, J | 1 |
| Seeger, W | 1 |
| Guenther, A | 1 |
| Ruppert, C | 1 |
| Gasse, P | 1 |
| Riteau, N | 1 |
| Charron, S | 1 |
| Girre, S | 1 |
| Fick, L | 1 |
| Pétrilli, V | 1 |
| Tschopp, J | 1 |
| Lagente, V | 1 |
| Quesniaux, VF | 1 |
| Ryffel, B | 1 |
| Couillin, I | 1 |
| Andersen, CU | 1 |
| Mellemkjær, S | 1 |
| Nielsen-Kudsk, JE | 1 |
| Bendstrup, E | 1 |
| Simonsen, U | 1 |
| Hilberg, O | 1 |
| Schwenk, HU | 1 |
| Schneider, U | 1 |
| Chopra, KF | 1 |
| Schneiderman, P | 1 |
| Grossman, ME | 1 |
| Klastersky, J | 1 |
| Fukuda, M | 1 |
| Inaba, R | 1 |
2 reviews available for uric acid and Pulmonary Fibrosis
| Article | Year |
|---|---|
Finger pad tophi.
Topics: Cyclosporine; Fingers; Follow-Up Studies; Gout; Gout Suppressants; Humans; Immunosuppressive Agents; | 1999 |
[Medical complications of chemotherapy].
Topics: Antineoplastic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Gastrointestina | 1975 |
6 other studies available for uric acid and Pulmonary Fibrosis
| Article | Year |
|---|---|
Fluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP3 inflammasome and IL-1β/IL-1R1/MyD88/NF-κB pathway.
Topics: Actins; Animals; Bleomycin; Caspase 1; Chemokine CCL2; Collagen Type I; Down-Regulation; Fibronectin | 2016 |
Alveolar oxidative stress is associated with elevated levels of nonenzymatic low-molecular-weight antioxidants in patients with different forms of chronic fibrosing interstitial lung diseases.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Bronchoalveolar Lavage Fl | 2009 |
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.
Topics: Allopurinol; Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Carrier Proteins; Disease | 2009 |
Diagnostic and prognostic role of biomarkers for pulmonary hypertension in interstitial lung disease.
Topics: Biomarkers; Cross-Sectional Studies; Fibrin Fibrinogen Degradation Products; Humans; Hypertension, P | 2012 |
[Life-threatening hyperuricemia during cytostatic leukemia therapy].
Topics: Adolescent; Allopurinol; Asparaginase; Child; Humans; Leukemia, Lymphoid; Male; Methylprednisolone; | 1982 |
[Tumor lysis syndrome, DIC and interstitial pneumonia after treatment with prednisolone and melphalan in a patient with acute monocytic leukemia with tumor formation].
Topics: Blood Urea Nitrogen; Disseminated Intravascular Coagulation; Humans; Hyperkalemia; Leukemia, Monocyt | 1987 |