uric acid has been researched along with Pulmonary Arterial Remodeling in 4 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increased oxidative stress and high uric acid are implicated in the pathogenesis of pulmonary hypertension (PH)." | 4.12 | Allopurinol treatment reduced vascular remodeling and improved vascular functions in monocrotaline-induced pulmonary hypertensive rats. ( Gokcen, T; Inci, EE; Inci, K; Serdar, U; Sevgen, O, 2022) |
| "Hypertension is the most important modifiable risk factor for stroke and is associated with poorer post-stroke outcomes." | 1.56 | Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats. ( Chamorro, Á; Dantas, AP; Jiménez-Altayó, F; Jiménez-Xarrié, E; Martí-Fabregas, J; Pérez, B; Planas, AM; Puertas-Umbert, L; Vila, E, 2020) |
| "Uric acid (UA) has been found to stimulate macrophage migration inhibitory factor (MIF) up-regulation in renal tubules from rats subjected to UA-induced nephropathy." | 1.51 | Blockage of macrophage migration inhibitory factor (MIF) suppressed uric acid-induced vascular inflammation, smooth muscle cell de-differentiation, and remodeling. ( Fu, X; Li, G; Liu, Q; Lou, Y; Mei, J; Niu, N; Qu, P; Sui, Z; Sun, J; Xu, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gokcen, T | 1 |
| Inci, K | 1 |
| Inci, EE | 1 |
| Sevgen, O | 1 |
| Serdar, U | 1 |
| Russo, E | 1 |
| Bertolotto, M | 1 |
| Zanetti, V | 1 |
| Picciotto, D | 1 |
| Esposito, P | 1 |
| Carbone, F | 1 |
| Montecucco, F | 1 |
| Pontremoli, R | 1 |
| Garibotto, G | 1 |
| Viazzi, F | 1 |
| Verzola, D | 1 |
| Jiménez-Xarrié, E | 1 |
| Pérez, B | 1 |
| Dantas, AP | 1 |
| Puertas-Umbert, L | 1 |
| Martí-Fabregas, J | 1 |
| Chamorro, Á | 1 |
| Planas, AM | 1 |
| Vila, E | 1 |
| Jiménez-Altayó, F | 1 |
| Fu, X | 1 |
| Niu, N | 1 |
| Li, G | 1 |
| Xu, M | 1 |
| Lou, Y | 1 |
| Mei, J | 1 |
| Liu, Q | 1 |
| Sui, Z | 1 |
| Sun, J | 1 |
| Qu, P | 1 |
4 other studies available for uric acid and Pulmonary Arterial Remodeling
| Article | Year |
|---|---|
Allopurinol treatment reduced vascular remodeling and improved vascular functions in monocrotaline-induced pulmonary hypertensive rats.
Topics: Allopurinol; Animals; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Ra | 2022 |
Role of Uric Acid in Vascular Remodeling: Cytoskeleton Changes and Migration in VSMCs.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Movement; | 2023 |
Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats.
Topics: Animals; Antioxidants; Brain Injuries; Cerebral Revascularization; Hypertension; Infarction, Middle | 2020 |
Blockage of macrophage migration inhibitory factor (MIF) suppressed uric acid-induced vascular inflammation, smooth muscle cell de-differentiation, and remodeling.
Topics: Animals; Cell Dedifferentiation; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques; | 2019 |