uric acid has been researched along with Pre-Eclampsia in 400 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To quantify the association between maternal uric acid levels and pre-eclampsia risk in a large collection of primigravid women." | 9.41 | Uric acid and risk of pre-eclampsia: results from a large case-control study and meta-analysis of prospective studies. ( Bautista-Niño, PK; Beltrán, M; Casas, JP; Colmenares-Mejia, CC; Gray, KJ; Guío, E; Paez, MC; Quintero-Lesmes, DC; Serrano, NC; Williams, D, 2023) |
| "The aim was to study the role of nitric oxide (NO), lipid peroxides (LPX), and uric acid in pre-eclampsia and eclampsia." | 9.11 | Nitric oxide, lipid peroxides, and uric acid levels in pre-eclampsia and eclampsia. ( Bulduk, G; Oğüş, E; Onalan, G; Paşaoğlu, A; Paşaoğlu, H, 2004) |
| "This meta-analysis aims to compare serum uric acid levels among preeclamptic and healthy pregnant women across the various trimesters and provide a summary of the effect size of this biomarker in predicting adverse pregnancy outcomes." | 9.05 | The prognostic role of serum uric acid levels in preeclampsia: A meta-analysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Pergialiotis, V, 2020) |
| "Because of the significant discrepancies on this topic, this review will focus on the role of uric acid in PE, uric acid as a predictor of preeclampsia and fetal growth retardation." | 8.98 | The Role of Uric Acid in Preeclampsia: Is Uric Acid a Causative Factor or a Sign of Preeclampsia? ( Khaliq, OP; Konoshita, T; Moodley, J; Naicker, T, 2018) |
| " Hyperuricemia is a key biochemical feature in preeclampsia with elevated levels of uric acid being diagnosed as early as the 10(th) week of gestation." | 8.91 | The involvement of uric acid in the pathogenesis of preeclampsia. ( Athanasiadis, A; Kourtis, A; Makedou, K; Masoura, S; Theodoridis, T; Zepiridis, L, 2015) |
| "The association between uric acid (UA) and pre-eclampsia has been known for years, but the prognostic value of UA has been debated." | 8.88 | Serum uric acid and pre-eclampsia: an update. ( Bellomo, G, 2012) |
| "Uric acid is a terminal metabolite of the degradation of nucleotides, which increases their blood levels in patients with preeclampsia-eclampsia, increasing its synthesis by damage and death of trophoblastic cells in proliferation and decreased urinary excretion due a lower glomerular filtration rate and increased absorption in the proximal tubule." | 8.87 | [Role of uric acid in preeclampsia-eclampsia]. ( Rico-Trejo, EI; Vázquez-Rodríguez, JG, 2011) |
| "Interest has been renewed over the role of uric acid in the pathogenesis of hypertension, endothelial dysfunction and renal dysfunction, which are all features of pre-eclampsia." | 8.86 | Could uric acid have a pathogenic role in pre-eclampsia? ( Brown, MA; Martin, AC, 2010) |
| "The aim of this study is to determine the accuracy and clinical value of serum uric acid in predicting maternal complications in women with pre-eclampsia." | 8.85 | Accuracy of serum uric acid as a predictive test for maternal complications in pre-eclampsia: bivariate meta-analysis and decision analysis. ( Aarnoudse, JG; Groen, H; Koopmans, CM; Mol, BW; van den Berg, PP; van Pampus, MG, 2009) |
| "To determine the accuracy with which serum uric acid predicts maternal and fetal complications in women with pre-eclampsia." | 8.83 | Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review. ( Coomarasamy, A; Ismail, KM; Khan, KS; Sharp, S; Thangaratinam, S, 2006) |
| "To systematically review the accuracy of determining serum uric acid before the 25th gestational week in predicting pre-eclampsia." | 8.83 | Accuracy of serum uric acid determination in predicting pre-eclampsia: a systematic review. ( Cnossen, JS; de Ruyter-Hanhijärvi, H; Khan, KS; Mol, BW; ter Riet, G; van der Post, JA, 2006) |
| "Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity." | 8.82 | Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link. ( Finch, J; Granger, J; Johnson, RJ; Kanellis, J; Kang, DH; Karumanchi, SA; Nakagawa, T, 2004) |
| " The objects of this study is to estimate and correlate the levels of NGAL (neutrophil gelatinase associated lipocalin), IMA (ischemia modified albumin) and Uric acid in prreclampsia." | 8.31 | Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia. ( Bhurer Yadav, B; Kaushik, P; Parasher, N; Singh, NK; Suri, A; Yadav, L, 2023) |
| "To elucidate whether uric acid changes in early pregnancy are associated with the development of preeclampsia and their association with preeclampsia-related adverse pregnancy outcomes." | 8.31 | Association of first trimester serum uric acid with preeclampsia: an observational cohort study with propensity score matching. ( Li, X; Ying, C; Yue, C, 2023) |
| " Pregnant women were divided into hyperuricemia-HU (uric acid ≥ 6 mg/dL) or normouricemia (uric acid, 2." | 8.12 | Serum uric acid levels associated with biochemical parameters linked to preeclampsia severity and to adverse perinatal outcomes. ( da Silva, JVF; de Mendonça, ELSS; de Oliveira, ACM; Mello, CS, 2022) |
| "This study aims to ascertain whether serum uric acid is a suitable predictor of preeclampsia and/or the delivery of small-for-gestational-age infants for women with gestational hypertension." | 8.02 | Uric acid levels in gestational hypertensive women predict preeclampsia and outcome of small-for-gestational-age infants. ( Duan, T; Frempong, ST; Zhao, X, 2021) |
| " This study aimed to explore what the role of calcium/creatinine ratio is in urine compared with proteinuria and uric acid in predicting preeclampsia." | 8.02 | Role of Calcium/Creatinine Ratio in Urine Compared with Proteinuria and Uric Acid in Predicting Preeclampsia: A Study from Kosovo. ( Ademi Ibishi, V; Bimbashi, A; Ibrahimi, L; Latifi Hoxha, S; Paçarada, M, 2021) |
| "To compare the distribution of uric acid (UA) concentration in women with normal and preeclamptic pregnancy, to investigate the significance of UA concentration in diagnosis of preeclampsia, and to estimate the UA rate of change over time before delivery." | 7.96 | Investigating the diagnostic capacity of uric acid in the occurrence of preeclampsia. ( Pasyar, S; Peng, YP; Pudwell, J; Smith, GN; Wilson, LM, 2020) |
| "To determine the relationship between maternal serum uric acid levels and fetal/neonatal complications in women with pre-eclampsia/eclampsia, and to establish a predictive threshold value." | 7.91 | Maternal serum uric acid concentration and pregnancy outcomes in women with pre-eclampsia/eclampsia. ( Cao, TN; Le, DD; Le, TM; Nguyen, HVQ; Nguyen, LH; Phan, NL; Truong, VQ, 2019) |
| "To assess the relationship between maternal serum uric acid and severity of Hypertensive disorders of pregnancy in a rural tertiary care centre." | 7.91 | Maternal Serum Uric Acid as a Predictor of Severity of Hypertensive Disorders of Pregnancy: A Prospective Cohort Study. ( Kumar, N; Singh, AK, 2019) |
| "Serum uric acid levels and protein excretion in women that develop eclampsia." | 7.91 | Increased proteinuria and uric acid levels are associated with eclamptic crisis. ( Antonello, IC; da Cunha Filho, EV; Hentschke, MR; Luz, JH; Paula, LG; Pinheiro da Costa, BE; Poli-de-Figueiredo, CE, 2019) |
| " Total 220 antenatal women ≥34 weeks of gestation with 110 cases having hypertensive disorder of pregnancy and 110 controls with normal blood pressure were compared for maternal uric acid and calcium levels and maternal, perinatal outcomes." | 7.91 | Maternal serum uric acid and calcium as predictors of hypertensive disorder of pregnancy: A case control study. ( Kumar, N; Singh, AK, 2019) |
| " Multiple logistic analysis adjusting for body mass index (BMI), lupus nephritis, serum uric acid, and estimated glomerular filtration rate revealed HCQ treatment was associated with exceedingly lower risk of preeclampsia in SLE pregnancy (odds ratio (OR) 0." | 7.91 | Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia. ( Cha, HS; Chae, J; Choi, SJ; Kim, YM; Oh, S; Roh, CR; Seo, MR, 2019) |
| " In our previous study, we showed that serum strontium (Sr) levels were elevated in preeclamptic women compared to healthy and GH pregnant women at the end of pregnancy." | 7.91 | Increased serum strontium levels and altered oxidative stress status in early-onset preeclampsia. ( Álvarez, FV; Barneo-Caragol, C; Lequerica-Fernández, P; Martínez-Morillo, E; Rodríguez-González, S; Vega-Naredo, I, 2019) |
| "The relationship between hyperuricemia and hypertensive disorders is well established; however, until today, the role of uric acid in the clinical course of severe preeclampsia has not been elucidated." | 7.88 | Uric Acid in Pregnancy: New Concepts. ( Briones Garduño, JC; Diaz de Leon Ponce, MA; Moreno Santillan, AA, 2018) |
| " Mean serum uric acid in gestational hypertension women with healthy foetuses was 5." | 7.85 | Impact of maternal serum uric acid on perinatal outcome in women with hypertensive disorders of pregnancy: A prospective study. ( Kumar, N; Maini, B; Singh, AK, 2017) |
| "It is controversial that uric acid (UA) levels are related to the severity of hypertension in preeclampsia (PE)." | 7.83 | The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia. ( Aliciguzel, Y; Elmas, O; Simsek, T, 2016) |
| " Lupus flares were predicted by HCQ discontinuation, a history of lupus nephritis, high pre-pregnancy serum uric acid and low C4 levels." | 7.81 | Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus. ( Ju, JH; Ko, HS; Koh, JH; Kwok, SK; Park, SH, 2015) |
| "We asked, is uric acid as effective as proteinuria at identifying perinatal risk in high-risk women with gestational hypertension? Uric acid was measured in samples obtained ≈4." | 7.81 | Uric Acid Determination in Gestational Hypertension: Is it as Effective a Delineator of Risk as Proteinuria in High-Risk Women? ( Althouse, AD; Clifton, RG; Roberts, JM; Schmella, MJ, 2015) |
| "The objective of this study was to evaluate the use of uric acid as a marker of severity of pre-eclampsia." | 7.80 | Association between uric acid and severity of pre-eclampsia. ( da Silva, JE; Knoppka, CK; Pereira, KN, 2014) |
| "An increased level of uric acid in urine and plasma is indicative of the development of preeclampsia, a hypertensive disorder that can occur during pregnancy." | 7.79 | Electrochemical-surface enhanced Raman spectroscopy (E-SERS) of uric acid: a potential rapid diagnostic method for early preeclampsia detection. ( Brosseau, CL; Goodall, BL; Robinson, AM, 2013) |
| "To examine the association between uric acid (UA) level during the first 20 weeks of pregnancy and the development of gestational diabetes mellitus (GDM) and preeclampsia in the second half of pregnancy." | 7.78 | High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia. ( Paran, E; Sergienko, R; Sheiner, E; Wiznitzer, A; Wolak, T, 2012) |
| " Women were grouped according to diagnosis (pre-eclampsia or gestational hypertension) and logistic regression analysis was used to determine the relationship between uric acid, haemoglobin, haematocrit and adverse outcomes; an α level of P < 0." | 7.78 | Plasma uric acid remains a marker of poor outcome in hypertensive pregnancy: a retrospective cohort study. ( Brown, MA; Davis, GK; Hawkins, TL; Mangos, GJ; Roberts, JM; Roberts, LM, 2012) |
| "The mean serum uric acid level at the initial presentation of gestational hypertension was significantly higher comparing patients who later progressed to preeclampsia to those who did not (5." | 7.78 | Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies. ( Fraser, WD; Luo, ZC; Wu, Y; Xiong, X, 2012) |
| "The objective of this study was to evaluate the predictive values of lipids and uric acid in mid-second trimester for adverse pregnancy outcome." | 7.78 | Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes. ( Hu, Y; Wang, Z; Zhao, X; Zhou, J, 2012) |
| "First trimester elevated uric acid was associated with later pre-eclampsia and more strongly with pre-eclampsia and gestational hypertension with hyperuricemia." | 7.77 | First trimester uric acid and adverse pregnancy outcomes. ( Catov, J; Gandley, RE; Laughon, SK; Powers, RW; Roberts, JM, 2011) |
| "Aim of our study was to ascertain, prospectively, whether serum uric acid is a suitable predictor of preeclampsia and/or the delivery of small-for-gestational-age infants in women with gestational hypertension." | 7.77 | Prognostic significance of serum uric acid in women with gestational hypertension. ( Bellomo, G; Narducci, PL; Saronio, P; Venanzi, S; Verdura, C, 2011) |
| "The purpose of this study was to assess a possible correlation between insulin resistance and uric acid levels in gestational hypertension (GH) and preeclampsia." | 7.73 | Elevated serum uric acid levels in gestational hypertension are correlated with insulin resistance. ( Cohen, O; Homko, CJ; Schiff, E; Sivan, E; Weisz, B, 2005) |
| "We investigated changes in serum uric acid across pregnancy in women with gestational hyperuricemia at delivery, with and without preeclampsia, compared with normal pregnant and women with preeclampsia without gestational hyperuricemia." | 7.73 | Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery. ( Bodnar, LM; Cooper, KM; Daftary, AR; Frank, MP; Gallaher, MJ; Ness, RB; Powers, RW; Roberts, JM, 2006) |
| "The object of this study was to determine whether serum uric acid, serum creatinine and urinary microprotein levels could be used to identify women who might subsequently develop pre-eclampsia during pregnancy." | 7.72 | The significance of serum uric acid, creatinine and urinary microprotein levels in predicting pre-eclampsia. ( Peiris, H; Weerasekera, DS, 2003) |
| "Single estimation of serum uric acid and creatinine levels early in pregnancy are of little value in the prediction of pre-eclampsia." | 7.72 | Serum albumin, creatinine, uric acid and hypertensive disorders of pregnancy. ( Adedapo, KS; Aimakhu, CO; Alu, FE; Odukogbe, AT; Ola, B; Olayemi, O; Salako, BL, 2003) |
| "Hyperhomocysteinemia is a risk factor in obstetrical complications such as pre-eclampsia, 'hemolysis, elevated liver enzymes, low platelet' (HELLP)-syndrome and placental insufficiency." | 7.72 | Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency. ( Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U, 2004) |
| "The present study investigated plasma activity of 5'-nucleotidase, a key enzyme in the production of adenosine, in pre-eclampsia, and evaluated the relationship between changes in 5'-nucleotidase activity, and levels of uric acid, endproduct of the purine metabolism, and the severity of pre-eclampsia." | 7.71 | Plasma 5'-nucleotidase activities and uric acid levels in women with pre-eclampsia. ( Araki, T; Doi, D; Ishino, H; Kiyokawa, Y; Kobayashi, H; Kuwabara, Y; Miura, A; Otsubo, Y; Sawa, R; Suzuki, S; Yoneyama, K; Yoneyama, Y, 2002) |
| "Our purpose was to evaluate the clinical utility of serum uric acid measurements in the hypertensive diseases of pregnancy." | 7.70 | The clinical utility of serum uric acid measurements in hypertensive diseases of pregnancy. ( Ecker, JL; Friedman, SA; Kao, L; Kilpatrick, SJ; Lim, KH, 1998) |
| "Our purpose was to evaluate the clinical utility of serum uric acid measurements in the hypertension diseases of pregnancy." | 7.70 | The clinical utility of serum uric acid measurements in pre-eclampsia and transient hypertension in pregnancy. ( Baviera, G; D'Anna, R; Leo, R; Leonardi, I; Scilipoti, A, 2000) |
| "Leptin concentrations have been found to be elevated in cross-sectional studies of established pre-eclampsia." | 7.70 | Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia. ( Anim-Nyame, N; Johnson, MR; Sooranna, SR; Steer, PJ, 2000) |
| "There is no evidence from this study to support the association between perinatal deaths and higher uric acid levels in patients with severe pre-eclampsia." | 7.69 | Are high uric acid levels in patients with early pre-eclampsia an indication for delivery? ( Odendaal, HJ; Pienaar, ME, 1997) |
| "In order to know if abnormalities of calcium metabolism may be involved in the pathophysiology of pregnancy-induced hypertension (PIH), as it has been incriminated in essential hypertension, we measured plasma and urinary calcium and phosphate as well as plasma PTH and free calcitriol index (ratio of total calcitriol on the D binding protein) in normotensive pregnant women (n = 25), in women with PIH after the same duration of amenorrhea (> 28 wk, n = 21:preeclampsia and 20 transient hypertensions), and in age-matched nonpregnant women (n = 15)." | 7.68 | Calcium metabolism, plasma parathyroid hormone, and calcitriol in transient hypertension of pregnancy. ( Bouillon, R; el Esper, N; Fournier, A; Jans, I; Lalau, JD, 1993) |
| "Serum calcium, urea and uric acid levels were determined in 100 normal pregnant women and 50 patients with pre-eclampsia." | 7.68 | Serum calcium, urea and uric acid levels in pre-eclampsia. ( Hassan, TJ; Jafarey, SN; Sadaruddin, A, 1991) |
| "Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension." | 7.67 | Atrial natriuretic peptide and arginine vasopressin in pregnancy and pregnancy-induced hypertension. ( Domurat, E; Elias, AN; Pandian, MR; Powers, DR; Vaziri, ND, 1988) |
| "Maximum serum uric acid (SUA) levels during the third trimester of pregnancy were selected in 215 hypertensive pregnant women: 100 with mild preeclampsia (PE), 25 with severe PE, 70 with essential hypertension (EH) and 20 with EH with superimposed PE (EH + PE)." | 7.67 | Uric acid levels: a useful index of the severity of preeclampsia and perinatal prognosis. ( Darbon-Grosso, HA; Illia, R; Imaz, FU; Margulies, M; Voto, LS, 1988) |
| "Single estimations of plasma urea, uric acid and creatinine were made in late pregnancy in 34 Nigerian primigravidae with mild/moderate or severe pregnancy-induced hypertension, and in 34 matched primigravidae with uncomplicated pregnancy." | 7.67 | Plasma concentration of urate, urea and creatinine in Nigerian primigravidae with pre-eclampsia. ( Egwuatu, VE, 1986) |
| "Fifty-four pregnancies that were subsequently complicated by preeclampsia had platelet parameters and uric acid levels measured during pregnancy." | 7.67 | Platelets and uric acid in the prediction of preeclampsia. ( Bromham, DR; Brooks, JA; Fay, RA; Gebski, VJ, 1985) |
| "A prospective longitudinal study was conducted, looking at the changes in serum uric acid during pregnancy in women who were normotensive at initial presentation." | 7.66 | Serum uric acid as a marker of pregnancy-induced hypertension. ( Hickman, PE; Michael, CA; Potter, JM, 1982) |
| "The authors have carried out research in 58 cases to see whether the findings of high uric acid levels in the blood are of prognostic value in all cases of arterial hypertension in pregnancy whatever the aetiology." | 7.66 | [The prognostic value of raised uric acid in the blood in arterial hypertension in pregnancy. 58 cases (author's transl)]. ( Cotteel, M; Delecour, M; Dequiedt, P; Leroy, JL; Potier, A; Puech, F; Tacquet, A, 1979) |
| "Purine inborn errors of metabolism (IEM) are serious hereditary disorders, which should be suspected in any case of neonatal fitting, failure to thrive, recurrent infections, neurological deficit, renal disease, self-mutilation and other manifestations." | 6.44 | Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions. ( Aquino Neto, FR; de Oliveira, ML; Gomes, LN; Oliveira, CP; Scalco, FB; Simoni, RE, 2007) |
| "Hyperuricemia is a common finding in preeclamptic pregnancies evident from early pregnancy." | 6.44 | Uric acid as a pathogenic factor in preeclampsia. ( Bainbridge, SA; Roberts, JM, 2008) |
| "The levels of CA 125 in mild and severe preeclampsia were (21." | 5.91 | Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023) |
| "Preeclampsia is one of the most severe diseases among the hypertensive disorders of pregnancy (HDP) and the leading cause of maternal and fetal morbidity and mortality." | 5.91 | Serum uric acid to creatinine ratio and risk of preeclampsia and adverse pregnancy outcomes. ( Agnoletti, D; Baracchi, A; Borghi, C; Degli Esposti, D; Montaguti, E; Piani, F; Scarduelli, S; Simonazzi, G; Tossetta, G; Verde, C, 2023) |
| "Clinical data of patients with preeclampsia were collected from the Medical Information Mart for Intensive Care (MIMIC)-IV database." | 5.91 | Uric acid as a mediator in the correlation between white blood cells and preeclampsia severity: a retrospective cohort study. ( He, CM; Hu, XY; Li, BJ; Zhu, TT, 2023) |
| "The study consisted of 170 cases (84 preeclampsia and 86 control)." | 5.72 | Role of derived neutrophil-to-lymphocyte ratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal outcomes in pregnancies with preeclampsia. ( Altinboğa, O; Elbayiyev, S; Erol, A; Şenel, S; Tanaçan, A; Yakiştiran, B; Yücel, A, 2022) |
| "The mean uric acid in women with preeclampsia was 6." | 5.72 | Association between maternal serum uric acid and preeclampsia. ( Fathi, L; Ghafarzadeh, M; Shakarami, A; Yari, F, 2022) |
| "Preeclampsia is defined as hypertension (systolic pressure ≥140 mmHg or diastolic pressure ≥90 mmHg) after week 20 of gestation with one or more of the following symptoms: proteinuria, organ dysfunction (including renal, hepatologic, hematologic or neurological complications) and in case of stagnation of fetal development." | 5.51 | Uric Acid Values Along with Doppler Sonography Findings as a Tool for Preeclampsia Screening. ( Dzihic, E; Iglica, A; Mahmutbegovic, E; Medjedovic, E; Muftic, A; Rama, A; Suljevic, A, 2019) |
| "Women were grouped according to status (preeclampsia or normotensive), and a logistic regression analysis was used to determine the relationship between serum uric acid levels and adverse outcomes." | 5.51 | Predictive value of serum uric acid levels for adverse perinatal outcomes in preeclampsia. ( Cho, NJ; Kim, YS; Lee, EY; Ryu, A, 2019) |
| "Uric acid levels in PE were significantly higher than in control groups (p < 0." | 5.48 | Strontium and its role in preeclampsia. ( Álvarez Menéndez, FV; Barneo-Caragol, C; Lequerica-Fernández, P; Martínez-Morillo, E; Rodríguez-González, S; Vega-Naredo, I, 2018) |
| "A total of 877 women with preeclampsia at presentation and 580 normotensive pregnancies were retrospectively recruited from January 2009 to May 2014." | 5.43 | Serum uric acid may not be involved in the development of preeclampsia. ( Chen, Q; Lau, S; Shen, F; Tong, M; Wei, J; Zhao, J; Zhao, M, 2016) |
| "Preeclampsia is a specific disorder of human pregnancy that is associated with hyperuricemia and higher levels of pro-inflammatory cytokines." | 5.43 | Elevated circulatingadenosine deaminase activity in women with preeclampsia: association with pro-inflammatory cytokine production and uric acid levels. ( Bannwart-Castro, CF; Borges, VT; Giorgi, VS; Peraçoli, JC; Peraçoli, MT; Romão-Veiga, M; Sartori, MS; Witkin, SS, 2016) |
| "The precise etiopathogenesis of preeclampsia (PE) still remains enigmatic." | 5.43 | Second trimester amniotic fluid uric acid, potassium, and cysteine to methionine ratio levels as possible signs of early preeclampsia: A case report. ( Athanasiadis, AP; Biliaderis, CG; Fotiou, M; Koulourida, V; Masoura, S; Menexes, G; Michaelidou, AM; Tarlatzis, BC, 2016) |
| "Uric acid crystals may activate an intracellular complex called inflammasome, which is important for processing and release of inflammatory cytokines." | 5.42 | Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia. ( Araújo, JP; Borges, VT; de Oliveira, L; Matias, ML; Nunes, PR; Peraçoli, JC; Peraçoli, MT; Ribeiro, VR; Romão, M; Weel, IC, 2015) |
| "To quantify the association between maternal uric acid levels and pre-eclampsia risk in a large collection of primigravid women." | 5.41 | Uric acid and risk of pre-eclampsia: results from a large case-control study and meta-analysis of prospective studies. ( Bautista-Niño, PK; Beltrán, M; Casas, JP; Colmenares-Mejia, CC; Gray, KJ; Guío, E; Paez, MC; Quintero-Lesmes, DC; Serrano, NC; Williams, D, 2023) |
| "Uric acid Z score was associated with adverse perinatal outcome (OR 1." | 5.40 | Uric Acid as a predictor of adverse maternal and perinatal outcomes in women hospitalized with preeclampsia. ( Brown, M; Côté, AM; Livingston, JR; Magee, LA; Payne, B; Roberts, JM; von Dadelszen, P, 2014) |
| "Uric acid levels were similar in both groups during the first half of gestation." | 5.40 | [Serum uric acid levels and risk of developing preeclampsia]. ( Balconi, SM; Corominas, AI; Damiano, AE; Maskin, B; Palermo, M, 2014) |
| "The presence of preeclampsia also correlated with greater supplemental uterotonic agent use (P=0." | 5.39 | Serum uric acid as a novel marker for uterine atony and post-spinal vasopressor use during cesarean delivery. ( Kovacheva, VP; Soens, MA; Tsen, LC, 2013) |
| "Uric acid is known to be elevated in preeclampsia." | 5.38 | Admission uric acid levels and length of expectant management in preterm preeclampsia. ( Bond, B; Craigo, SD; Norwitz, ER; Paulus, JK; Strohsnitter, WC; Urato, AC, 2012) |
| "Because preeclampsia is associated with placental immune⁄ inflammatory dysregulation, we sought to determine in the trophoblast, the presence of the Nalp3 inflammasome, and the effect of MSU on its activation." | 5.37 | Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia. ( Abrahams, VM; Boeras, C; Guller, S; Kavathas, PB; Mulla, MJ; Myrtolli, K; Norwitz, ER; Potter, J; Sfakianaki, AK; Tadesse, S, 2011) |
| "Leptin has a promising future as a valuable marker to identity women with a high risk for preeclampsia." | 5.36 | Leptin levels and antihypertensive treatment in preeclampsia. ( Gungor, T; Kanat-Pektas, M; Mollamahmutoglu, L; Sucak, A, 2010) |
| "Medical records of patients with preeclampsia and patients with PIH who delivered at term between January 2003 and December 2004 were reviewed." | 5.35 | Retinopathy in preeclampsia: association with birth weight and uric acid level. ( Gupta, A; Kaliaperumal, S; Rao, VA; Setia, S; Suchi, ST, 2008) |
| "Forty-four women (29%) developed preeclampsia (preeclampsia group) at 33." | 5.30 | Elevation of the serum uric acid level preceding the clinical manifestation of preeclampsia in twin pregnancies. ( Koike, T; Kuwata, T; Minakami, H; Ogawa, S; Sato, I; Takayama, T, 1997) |
| " In the setting of hypertensive disorders of pregnancy, oral antihypertensive medications should be initiated when systolic blood pressure is greater than 160 mm Hg or when diastolic blood pressure is greater than 110 mm Hg, with the most ideal agents being labetalol or nifedipine." | 5.22 | Hypertensive Disorders of Pregnancy: Common Clinical Conundrums. ( Dotters-Katz, S; Kuller, JA; Lim, SL; Ohamadike, O; Siegel, A; Zemtsov, G, 2022) |
| "The aim was to study the role of nitric oxide (NO), lipid peroxides (LPX), and uric acid in pre-eclampsia and eclampsia." | 5.11 | Nitric oxide, lipid peroxides, and uric acid levels in pre-eclampsia and eclampsia. ( Bulduk, G; Oğüş, E; Onalan, G; Paşaoğlu, A; Paşaoğlu, H, 2004) |
| "This meta-analysis aims to compare serum uric acid levels among preeclamptic and healthy pregnant women across the various trimesters and provide a summary of the effect size of this biomarker in predicting adverse pregnancy outcomes." | 5.05 | The prognostic role of serum uric acid levels in preeclampsia: A meta-analysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Pergialiotis, V, 2020) |
| "High serum uric acid seems to be associated with pre-eclampsia." | 5.05 | Predictive value of serum uric acid levels for adverse maternal and perinatal outcomes in pregnant women with high blood pressure. A systematic review and meta-analysis. ( Pecoraro, V; Trenti, T, 2020) |
| "Because of the significant discrepancies on this topic, this review will focus on the role of uric acid in PE, uric acid as a predictor of preeclampsia and fetal growth retardation." | 4.98 | The Role of Uric Acid in Preeclampsia: Is Uric Acid a Causative Factor or a Sign of Preeclampsia? ( Khaliq, OP; Konoshita, T; Moodley, J; Naicker, T, 2018) |
| " Hyperuricemia is a key biochemical feature in preeclampsia with elevated levels of uric acid being diagnosed as early as the 10(th) week of gestation." | 4.91 | The involvement of uric acid in the pathogenesis of preeclampsia. ( Athanasiadis, A; Kourtis, A; Makedou, K; Masoura, S; Theodoridis, T; Zepiridis, L, 2015) |
| "The association between uric acid (UA) and pre-eclampsia has been known for years, but the prognostic value of UA has been debated." | 4.88 | Serum uric acid and pre-eclampsia: an update. ( Bellomo, G, 2012) |
| "Uric acid is a terminal metabolite of the degradation of nucleotides, which increases their blood levels in patients with preeclampsia-eclampsia, increasing its synthesis by damage and death of trophoblastic cells in proliferation and decreased urinary excretion due a lower glomerular filtration rate and increased absorption in the proximal tubule." | 4.87 | [Role of uric acid in preeclampsia-eclampsia]. ( Rico-Trejo, EI; Vázquez-Rodríguez, JG, 2011) |
| "Interest has been renewed over the role of uric acid in the pathogenesis of hypertension, endothelial dysfunction and renal dysfunction, which are all features of pre-eclampsia." | 4.86 | Could uric acid have a pathogenic role in pre-eclampsia? ( Brown, MA; Martin, AC, 2010) |
| "The aim of this study is to determine the accuracy and clinical value of serum uric acid in predicting maternal complications in women with pre-eclampsia." | 4.85 | Accuracy of serum uric acid as a predictive test for maternal complications in pre-eclampsia: bivariate meta-analysis and decision analysis. ( Aarnoudse, JG; Groen, H; Koopmans, CM; Mol, BW; van den Berg, PP; van Pampus, MG, 2009) |
| "To determine the accuracy with which serum uric acid predicts maternal and fetal complications in women with pre-eclampsia." | 4.83 | Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review. ( Coomarasamy, A; Ismail, KM; Khan, KS; Sharp, S; Thangaratinam, S, 2006) |
| "To systematically review the accuracy of determining serum uric acid before the 25th gestational week in predicting pre-eclampsia." | 4.83 | Accuracy of serum uric acid determination in predicting pre-eclampsia: a systematic review. ( Cnossen, JS; de Ruyter-Hanhijärvi, H; Khan, KS; Mol, BW; ter Riet, G; van der Post, JA, 2006) |
| "Pre-eclampsia is strongly associated with hyperuricemia, and in some studies the increase in serum uric acid has been found to correlate with both maternal and fetal morbidity." | 4.82 | Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link. ( Finch, J; Granger, J; Johnson, RJ; Kanellis, J; Kang, DH; Karumanchi, SA; Nakagawa, T, 2004) |
| " The objects of this study is to estimate and correlate the levels of NGAL (neutrophil gelatinase associated lipocalin), IMA (ischemia modified albumin) and Uric acid in prreclampsia." | 4.31 | Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia. ( Bhurer Yadav, B; Kaushik, P; Parasher, N; Singh, NK; Suri, A; Yadav, L, 2023) |
| "To elucidate whether uric acid changes in early pregnancy are associated with the development of preeclampsia and their association with preeclampsia-related adverse pregnancy outcomes." | 4.31 | Association of first trimester serum uric acid with preeclampsia: an observational cohort study with propensity score matching. ( Li, X; Ying, C; Yue, C, 2023) |
| " The exposure factor was serum uric acid before 24 weeks of gestation, primary outcome was gestational diabetes diagnosed at 24 to 28 weeks of gestation, and secondary outcomes were GDM A2 (GDM requiring pharmacotherapy), GDM combined with pre-eclampsia, preterm delivery, and large for gestational age infants." | 4.31 | Elevated Serum Uric Acid Is Associated With Gestational Diabetes Mellitus: An Observational Cohort Study. ( Li, X; Ying, C; Yue, C, 2023) |
| " Pregnant women were divided into hyperuricemia-HU (uric acid ≥ 6 mg/dL) or normouricemia (uric acid, 2." | 4.12 | Serum uric acid levels associated with biochemical parameters linked to preeclampsia severity and to adverse perinatal outcomes. ( da Silva, JVF; de Mendonça, ELSS; de Oliveira, ACM; Mello, CS, 2022) |
| "The current electronic laboratory order set at Epsom and St Helier University Hospitals NHS Trust for suspected pre-eclampsia includes a full blood count, urea and electrolytes, liver function, gamma-glutamyltransferase and uric acid." | 4.12 | Reducing laboratory costs through rational testing in suspected pre-eclampsia. ( Cox, M; Drane, S; Jakes, AD; Johnson, A, 2022) |
| "This study aims to ascertain whether serum uric acid is a suitable predictor of preeclampsia and/or the delivery of small-for-gestational-age infants for women with gestational hypertension." | 4.02 | Uric acid levels in gestational hypertensive women predict preeclampsia and outcome of small-for-gestational-age infants. ( Duan, T; Frempong, ST; Zhao, X, 2021) |
| "Pre-eclampsia is commonly associated with higher serum uric acid levels, which is known to increase vascular tone." | 4.02 | Association of Maternal Hyperuricemia with Post-Spinal Hypotension in Pre-Eclamptic Parturients Undergoing Emergency Cesarean Delivery: a Prospective Observational Study. ( Bhatia, N; Jain, K; Mehra, D; Sikka, P; Singla, K; Verma, I, 2021) |
| " This study aimed to explore what the role of calcium/creatinine ratio is in urine compared with proteinuria and uric acid in predicting preeclampsia." | 4.02 | Role of Calcium/Creatinine Ratio in Urine Compared with Proteinuria and Uric Acid in Predicting Preeclampsia: A Study from Kosovo. ( Ademi Ibishi, V; Bimbashi, A; Ibrahimi, L; Latifi Hoxha, S; Paçarada, M, 2021) |
| "To compare the distribution of uric acid (UA) concentration in women with normal and preeclamptic pregnancy, to investigate the significance of UA concentration in diagnosis of preeclampsia, and to estimate the UA rate of change over time before delivery." | 3.96 | Investigating the diagnostic capacity of uric acid in the occurrence of preeclampsia. ( Pasyar, S; Peng, YP; Pudwell, J; Smith, GN; Wilson, LM, 2020) |
| "To determine the relationship between maternal serum uric acid levels and fetal/neonatal complications in women with pre-eclampsia/eclampsia, and to establish a predictive threshold value." | 3.91 | Maternal serum uric acid concentration and pregnancy outcomes in women with pre-eclampsia/eclampsia. ( Cao, TN; Le, DD; Le, TM; Nguyen, HVQ; Nguyen, LH; Phan, NL; Truong, VQ, 2019) |
| "To assess the relationship between maternal serum uric acid and severity of Hypertensive disorders of pregnancy in a rural tertiary care centre." | 3.91 | Maternal Serum Uric Acid as a Predictor of Severity of Hypertensive Disorders of Pregnancy: A Prospective Cohort Study. ( Kumar, N; Singh, AK, 2019) |
| "Serum uric acid levels and protein excretion in women that develop eclampsia." | 3.91 | Increased proteinuria and uric acid levels are associated with eclamptic crisis. ( Antonello, IC; da Cunha Filho, EV; Hentschke, MR; Luz, JH; Paula, LG; Pinheiro da Costa, BE; Poli-de-Figueiredo, CE, 2019) |
| " Total 220 antenatal women ≥34 weeks of gestation with 110 cases having hypertensive disorder of pregnancy and 110 controls with normal blood pressure were compared for maternal uric acid and calcium levels and maternal, perinatal outcomes." | 3.91 | Maternal serum uric acid and calcium as predictors of hypertensive disorder of pregnancy: A case control study. ( Kumar, N; Singh, AK, 2019) |
| " Multiple logistic analysis adjusting for body mass index (BMI), lupus nephritis, serum uric acid, and estimated glomerular filtration rate revealed HCQ treatment was associated with exceedingly lower risk of preeclampsia in SLE pregnancy (odds ratio (OR) 0." | 3.91 | Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia. ( Cha, HS; Chae, J; Choi, SJ; Kim, YM; Oh, S; Roh, CR; Seo, MR, 2019) |
| " In our previous study, we showed that serum strontium (Sr) levels were elevated in preeclamptic women compared to healthy and GH pregnant women at the end of pregnancy." | 3.91 | Increased serum strontium levels and altered oxidative stress status in early-onset preeclampsia. ( Álvarez, FV; Barneo-Caragol, C; Lequerica-Fernández, P; Martínez-Morillo, E; Rodríguez-González, S; Vega-Naredo, I, 2019) |
| "The relationship between hyperuricemia and hypertensive disorders is well established; however, until today, the role of uric acid in the clinical course of severe preeclampsia has not been elucidated." | 3.88 | Uric Acid in Pregnancy: New Concepts. ( Briones Garduño, JC; Diaz de Leon Ponce, MA; Moreno Santillan, AA, 2018) |
| "Pre-eclampsia is associated with increased levels of cholesterol and uric acid and an inflamed placenta expressing danger-sensing pattern recognition receptors (PRRs)." | 3.88 | Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts. ( Aune, MH; Bjørge, L; Dahlberg, UE; Gierman, LM; Iversen, AC; Nervik, I; Silva, GB; Stødle, GS; Sun, C; Tangerås, LH; Thomsen, LCV, 2018) |
| " Mean serum uric acid in gestational hypertension women with healthy foetuses was 5." | 3.85 | Impact of maternal serum uric acid on perinatal outcome in women with hypertensive disorders of pregnancy: A prospective study. ( Kumar, N; Maini, B; Singh, AK, 2017) |
| "The levels of C-reactive protein, blood urea nitrogen, serum uric acid, and alanine transaminase, and the platelet count were linked with the presence and severity of pre-eclampsia." | 3.85 | Association of biochemical markers with the severity of pre-eclampsia. ( Aid, G; Bassiouny, N; Dahab, S; Eldin, DS; Ghamry, NK; Maged, AM, 2017) |
| "It is controversial that uric acid (UA) levels are related to the severity of hypertension in preeclampsia (PE)." | 3.83 | The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia. ( Aliciguzel, Y; Elmas, O; Simsek, T, 2016) |
| "To evaluate diagnostic value of ceruloplasmin together with other enzymatic and nonenzymatic antioxidants (superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and uric acid) and to evaluate the level of oxidative stress in patients with pre-eclampsia (PE) and compare it with normal pregnancy." | 3.83 | Ceruloplasmin and antioxidative enzymes in pre-eclampsia. ( Cabarkapa, V; Jakovljević, A; Nikolic, A; Novakov Mikic, A; Stosic, Z, 2016) |
| " Lupus flares were predicted by HCQ discontinuation, a history of lupus nephritis, high pre-pregnancy serum uric acid and low C4 levels." | 3.81 | Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus. ( Ju, JH; Ko, HS; Koh, JH; Kwok, SK; Park, SH, 2015) |
| "We asked, is uric acid as effective as proteinuria at identifying perinatal risk in high-risk women with gestational hypertension? Uric acid was measured in samples obtained ≈4." | 3.81 | Uric Acid Determination in Gestational Hypertension: Is it as Effective a Delineator of Risk as Proteinuria in High-Risk Women? ( Althouse, AD; Clifton, RG; Roberts, JM; Schmella, MJ, 2015) |
| " Measurements included clinical and ambulatory blood pressure monitoring, ultrasound-measured flow-mediated dilatation (FMD), microalbuminuria, carotid intima-media thickness (CIMT) and serum uric acid, as well as clinical and demographic features." | 3.81 | Persistence of cardiovascular risk factors in women with previous preeclampsia: a long-term follow-up study. ( Acmaz, G; Afsar, B; Aykas, F; Bulut, K; Covic, A; Dogan, S; Erden, A; Johnson, RJ; Kanbay, M; Sarli, B; Sharma, S; Siriopol, D; Solak, Y, 2015) |
| "The objective of this study was to evaluate the use of uric acid as a marker of severity of pre-eclampsia." | 3.80 | Association between uric acid and severity of pre-eclampsia. ( da Silva, JE; Knoppka, CK; Pereira, KN, 2014) |
| " Significant changes of biochemical parameters in cases of hypertensive disorders in pregnancy are increased levels of blood glucose, urea, creatinine, uric acid (hyperuricemia), transaminases, and LDH." | 3.79 | Correlation of biochemical parameters and neonatal outcome in patients with gestational hypertension. ( Aksam, S; Kocijancic, A; Kocijancic, DM; Plecas, D; Plesinac, S, 2013) |
| "An increased level of uric acid in urine and plasma is indicative of the development of preeclampsia, a hypertensive disorder that can occur during pregnancy." | 3.79 | Electrochemical-surface enhanced Raman spectroscopy (E-SERS) of uric acid: a potential rapid diagnostic method for early preeclampsia detection. ( Brosseau, CL; Goodall, BL; Robinson, AM, 2013) |
| "In women with SLE with mild-moderate disease activity, ferritin, oestradiol and uric acid levels at mid-gestation may predict preterm birth." | 3.79 | Predictors of preterm birth in patients with mild systemic lupus erythematosus. ( Clowse, ME; Criscione-Schreiber, LG; James, A; Pisetsky, DS; Wallace, DJ; Weisman, M, 2013) |
| "To examine the association between uric acid (UA) level during the first 20 weeks of pregnancy and the development of gestational diabetes mellitus (GDM) and preeclampsia in the second half of pregnancy." | 3.78 | High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia. ( Paran, E; Sergienko, R; Sheiner, E; Wiznitzer, A; Wolak, T, 2012) |
| "Cystatin C serum level may have significant role as a marker of pre-eclampsia specially when used in combination with uric acid levels." | 3.78 | Cystatin C in pre-eclampsia. ( Brkic, S; Cabarkapa, V; Maric, D; Mitic, G; Nikolic, A; Novakov Mikic, A; Ristic, M; Stosic, Z, 2012) |
| " Women were grouped according to diagnosis (pre-eclampsia or gestational hypertension) and logistic regression analysis was used to determine the relationship between uric acid, haemoglobin, haematocrit and adverse outcomes; an α level of P < 0." | 3.78 | Plasma uric acid remains a marker of poor outcome in hypertensive pregnancy: a retrospective cohort study. ( Brown, MA; Davis, GK; Hawkins, TL; Mangos, GJ; Roberts, JM; Roberts, LM, 2012) |
| "The mean serum uric acid level at the initial presentation of gestational hypertension was significantly higher comparing patients who later progressed to preeclampsia to those who did not (5." | 3.78 | Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies. ( Fraser, WD; Luo, ZC; Wu, Y; Xiong, X, 2012) |
| "The objective of this study was to evaluate the predictive values of lipids and uric acid in mid-second trimester for adverse pregnancy outcome." | 3.78 | Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes. ( Hu, Y; Wang, Z; Zhao, X; Zhou, J, 2012) |
| "First trimester elevated uric acid was associated with later pre-eclampsia and more strongly with pre-eclampsia and gestational hypertension with hyperuricemia." | 3.77 | First trimester uric acid and adverse pregnancy outcomes. ( Catov, J; Gandley, RE; Laughon, SK; Powers, RW; Roberts, JM, 2011) |
| "This study investigated serum uric acid levels, monocyte production of TNF-α, superoxide anion (O(2)(-)) and hydrogen peroxide (H(2)O(2)), as well as superoxide dismutase (SOD) and catalase (CAT) activities in erythrocytes from 30 women with pre-eclampsia (PE) compared with 30 normotensive (NT) pregnant women in the last trimester of pregnancy." | 3.77 | Increased reactive oxygen species and tumor necrosis factor-alpha production by monocytes are associated with elevated levels of uric acid in pre-eclamptic women. ( Bannwart, CF; Borges, VT; Costa, RA; Cristofalo, R; Peraçoli, JC; Peraçoli, MT; Witkin, SS, 2011) |
| "Aim of our study was to ascertain, prospectively, whether serum uric acid is a suitable predictor of preeclampsia and/or the delivery of small-for-gestational-age infants in women with gestational hypertension." | 3.77 | Prognostic significance of serum uric acid in women with gestational hypertension. ( Bellomo, G; Narducci, PL; Saronio, P; Venanzi, S; Verdura, C, 2011) |
| " More recently it has been suggested that uric acid may directly contribute to pathological cell signaling events involved in disease progression as well as maternal and fetal pregnancy outcomes including fetal growth restriction." | 3.75 | Uric acid inhibits placental system A amino acid uptake. ( Bainbridge, SA; Roberts, JM; von Versen-Höynck, F, 2009) |
| "The purpose of this study was to assess a possible correlation between insulin resistance and uric acid levels in gestational hypertension (GH) and preeclampsia." | 3.73 | Elevated serum uric acid levels in gestational hypertension are correlated with insulin resistance. ( Cohen, O; Homko, CJ; Schiff, E; Sivan, E; Weisz, B, 2005) |
| "We investigated changes in serum uric acid across pregnancy in women with gestational hyperuricemia at delivery, with and without preeclampsia, compared with normal pregnant and women with preeclampsia without gestational hyperuricemia." | 3.73 | Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery. ( Bodnar, LM; Cooper, KM; Daftary, AR; Frank, MP; Gallaher, MJ; Ness, RB; Powers, RW; Roberts, JM, 2006) |
| "During normal pregnancy, plasma concentrations of creatinine and uric acid normally decrease as a consequence of their increased glomerular filtration." | 3.73 | Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus. ( Danişman, N; Güngör, ES; Mollamahmutoğlu, L, 2006) |
| "The object of this study was to determine whether serum uric acid, serum creatinine and urinary microprotein levels could be used to identify women who might subsequently develop pre-eclampsia during pregnancy." | 3.72 | The significance of serum uric acid, creatinine and urinary microprotein levels in predicting pre-eclampsia. ( Peiris, H; Weerasekera, DS, 2003) |
| "These data show that that microvascular filtration capacity is significantly increased in pre-eclampsia, and correlates with circulating levels of TNF-alpha but not leptin or VEGF." | 3.72 | Microvascular permeability is related to circulating levels of tumour necrosis factor-alpha in pre-eclampsia. ( Anim-Nyame, N; Gamble, J; Johnson, MR; Sooranna, SR; Steer, PJ, 2003) |
| "Single estimation of serum uric acid and creatinine levels early in pregnancy are of little value in the prediction of pre-eclampsia." | 3.72 | Serum albumin, creatinine, uric acid and hypertensive disorders of pregnancy. ( Adedapo, KS; Aimakhu, CO; Alu, FE; Odukogbe, AT; Ola, B; Olayemi, O; Salako, BL, 2003) |
| " Univariate analysis revealed statistical significance for the following variables associated with eclampsia: systolic hypertension > or =160 mmHg and diastolic > or =110 mmHg, headache, visual symptoms, vivid deep tendon reflexes, proteinuria >3+ or >3 g d(-1), uric acid concentration > or =350 micromol l(-1), serum creatinine concentration >100 micromol l(-1) and aminotransferase aspartate >30 IU l(-1)." | 3.72 | [Risk factors for eclampsia: a case-control study]. ( Arfaoui, C; Ben Salem, F; Ben Salem, K; Faleh, R; Gahbiche, M; Grati, L; Guerdelly, I; Jmel, A, 2003) |
| "Hyperhomocysteinemia is a risk factor in obstetrical complications such as pre-eclampsia, 'hemolysis, elevated liver enzymes, low platelet' (HELLP)-syndrome and placental insufficiency." | 3.72 | Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency. ( Geisel, J; Herrmann, W; Hübner, U; Koch, I; Obeid, R; Retzke, U, 2004) |
| " Their serum uric acid levels were correlated with the development of HELLP syndrome, severity of hypertension, and incidence of SGA newborns (< 10th percentile birth weight)." | 3.71 | The role of serum uric acid as a prognostic indicator of the severity of maternal and fetal complications in hypertensive pregnancies. ( Galerneau, F; Williams, KP, 2002) |
| "The present study investigated plasma activity of 5'-nucleotidase, a key enzyme in the production of adenosine, in pre-eclampsia, and evaluated the relationship between changes in 5'-nucleotidase activity, and levels of uric acid, endproduct of the purine metabolism, and the severity of pre-eclampsia." | 3.71 | Plasma 5'-nucleotidase activities and uric acid levels in women with pre-eclampsia. ( Araki, T; Doi, D; Ishino, H; Kiyokawa, Y; Kobayashi, H; Kuwabara, Y; Miura, A; Otsubo, Y; Sawa, R; Suzuki, S; Yoneyama, K; Yoneyama, Y, 2002) |
| "Our objective was to determine whether two methylxanthines, pentoxifylline (PTX) and allopurinol, would have beneficial effects on experimental pregnancy-induced pre-eclampsia- like disease in ewes." | 3.71 | Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes. ( Németh, I; Pintér, S; Tálosi, G, 2001) |
| "Retrospective study of two groups of women, one found to have lone hyperuricemia during pregnancy (n=102) and the others with normal serum uric acid levels (n=100)." | 3.70 | Lone hyperuricemia during pregnancy: maternal and fetal outcomes. ( Ba, R; Beaufils, M; Breart, G; Merviel, P; Salat-Baroux, J; Uzan, S, 1998) |
| "Our purpose was to evaluate the clinical utility of serum uric acid measurements in the hypertensive diseases of pregnancy." | 3.70 | The clinical utility of serum uric acid measurements in hypertensive diseases of pregnancy. ( Ecker, JL; Friedman, SA; Kao, L; Kilpatrick, SJ; Lim, KH, 1998) |
| "Univariate analysis revealed statistical significance for the following variables associated with eclampsia: uric acid concentration, > 8." | 3.70 | Risk factors for abruptio placentae and eclampsia: analysis of 445 consecutively managed women with severe preeclampsia and eclampsia. ( Mattar, F; Saade, GR; Sibai, BM; Witlin, AG, 1999) |
| "The presence of nausea and vomiting, epigastric pain, or both in association with admission laboratory values that are in excess of the cutoffs for lactate dehydrogenase, aspartate aminotransferase, and uric acid concentrations or for all 6 tests is predictive of high risk of morbidity for the patient with severe preeclampsia." | 3.70 | Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999) |
| "Significantly higher values were found in the preeclampsia than in the control group for fasting insulin, fasting glucose, fasting insulin resistance index (FIRI, fasting glucose x fasting insulin/25), serum triglycerides, uric acid and blood pressure." | 3.70 | Is carbohydrate metabolism altered among women who have undergone a preeclamptic pregnancy? ( Carlström, K; Erikssen, C; Nisell, H; Persson, B, 1999) |
| "The aim of the present research was to compare the uric acid, sodium and potassium excretions among patients with mild preeclampsia and normotensive pregnancy and to determine their behavior towards an acute physiologic state of hyperglycemia-hyperinsulinemia." | 3.70 | [Excretion of uric aid, sodium, and potassium in preeclampsia patients and its behavior in acute hyperglycemia-hyperinsulinemia]. ( González-Ortiz, M; Grover-Páez, F; Martínez-Abundis, E; Vera-Hernández, A, 1999) |
| "Our purpose was to evaluate the clinical utility of serum uric acid measurements in the hypertension diseases of pregnancy." | 3.70 | The clinical utility of serum uric acid measurements in pre-eclampsia and transient hypertension in pregnancy. ( Baviera, G; D'Anna, R; Leo, R; Leonardi, I; Scilipoti, A, 2000) |
| "Leptin concentrations have been found to be elevated in cross-sectional studies of established pre-eclampsia." | 3.70 | Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia. ( Anim-Nyame, N; Johnson, MR; Sooranna, SR; Steer, PJ, 2000) |
| "Plasma and cerebrospinal fluid total peroxyl radical-trapping antioxidative parameter (TRAP) and the main antioxidant components of TRAP (vitamin E, ascorbic acid, uric acid, protein sulfhydryl groups, and the unidentified antioxidant proportion) were analyzed in 11 preeclamptic parturients, 9 healthy parturients with an uncomplicated pregnancy, and 10 healthy nonpregnant women." | 3.69 | The total peroxyl radical-trapping ability of plasma and cerebrospinal fluid in normal and preeclamptic parturients. ( Kirkkola, AL; Metsä-Ketelä, T; Rorarius, M; Tuimala, RJ; Uotila, JT, 1994) |
| " The biopsy findings of the placental bed were compared with adequate weight at birth related to gestational age, and to the following clinical parameters of the mother: arterial blood pressure, serum creatinine, serum uric acid and proteinuria." | 3.69 | Placental bed lesions and infant birth weight in hypertensive pregnant women. ( Costa, CA; Edelweiss, MI; Martins-Costa, S; Ramos, JG, 1995) |
| "Although the systemic physiological alterations present in pre-eclampsia appear disparate and unrelated, four of them (endothelial cell hyperplasia and alterations in uric acid, calcium, and prostaglandin homeostasis) are demonstrated here to mimic closely the pattern of intracellular alterations caused by the activation of a G protein-associated receptor." | 3.69 | Pre-eclampsia: excessive activation of a G protein-associated receptor? ( Coffey, CG, 1995) |
| "To determine the usefulness of platelet count, mean platelet volume and serum uric acid levels in the prediction of pre-eclampsia in women with mild hypertension in pregnancy, and to see if it is appropriate to base the management of such patients on these tests." | 3.69 | Poor predictive value of platelet count, mean platelet volume and serum urate in hypertension in pregnancy. ( Calvert, SM; Haley, J; Tuffnell, DJ, 1996) |
| "Serum uric acid estimation was done in forty primigravidae with pregnancy induced hypertension and twenty normotensive primigravida in the third trimester of pregnancy, at delivery and six weeks postpartum." | 3.69 | Hyperuricemia and pregnancy induced hypertension--reappraisal. ( Dhaliwal, L; Gopalan, S; Mustaphi, R; Sarkar, AK, 1996) |
| "There is no evidence from this study to support the association between perinatal deaths and higher uric acid levels in patients with severe pre-eclampsia." | 3.69 | Are high uric acid levels in patients with early pre-eclampsia an indication for delivery? ( Odendaal, HJ; Pienaar, ME, 1997) |
| "In order to know if abnormalities of calcium metabolism may be involved in the pathophysiology of pregnancy-induced hypertension (PIH), as it has been incriminated in essential hypertension, we measured plasma and urinary calcium and phosphate as well as plasma PTH and free calcitriol index (ratio of total calcitriol on the D binding protein) in normotensive pregnant women (n = 25), in women with PIH after the same duration of amenorrhea (> 28 wk, n = 21:preeclampsia and 20 transient hypertensions), and in age-matched nonpregnant women (n = 15)." | 3.68 | Calcium metabolism, plasma parathyroid hormone, and calcitriol in transient hypertension of pregnancy. ( Bouillon, R; el Esper, N; Fournier, A; Jans, I; Lalau, JD, 1993) |
| "Serum calcium, urea and uric acid levels were determined in 100 normal pregnant women and 50 patients with pre-eclampsia." | 3.68 | Serum calcium, urea and uric acid levels in pre-eclampsia. ( Hassan, TJ; Jafarey, SN; Sadaruddin, A, 1991) |
| "Atrial natriuretic peptide (ANP) and arginine vasopressin concentrations were measured in 9 patients with pregnancy-induced hypertension." | 3.67 | Atrial natriuretic peptide and arginine vasopressin in pregnancy and pregnancy-induced hypertension. ( Domurat, E; Elias, AN; Pandian, MR; Powers, DR; Vaziri, ND, 1988) |
| "Maximum serum uric acid (SUA) levels during the third trimester of pregnancy were selected in 215 hypertensive pregnant women: 100 with mild preeclampsia (PE), 25 with severe PE, 70 with essential hypertension (EH) and 20 with EH with superimposed PE (EH + PE)." | 3.67 | Uric acid levels: a useful index of the severity of preeclampsia and perinatal prognosis. ( Darbon-Grosso, HA; Illia, R; Imaz, FU; Margulies, M; Voto, LS, 1988) |
| "In pregnancy there is a rise in glomerular filtration rate (GFR), plasma aldosterone levels, uric acid clearance and urinary kallikrein excretion." | 3.67 | Progesterone increases glomerular filtration rate, urinary kallikrein excretion and uric acid clearance in normal women. ( Atallah, AN; Camano, L; Gebara, M; Guimarães, JA; Martinez, TR; Sustovich, DR, 1988) |
| "Single estimations of plasma urea, uric acid and creatinine were made in late pregnancy in 34 Nigerian primigravidae with mild/moderate or severe pregnancy-induced hypertension, and in 34 matched primigravidae with uncomplicated pregnancy." | 3.67 | Plasma concentration of urate, urea and creatinine in Nigerian primigravidae with pre-eclampsia. ( Egwuatu, VE, 1986) |
| "Fifty-four pregnancies that were subsequently complicated by preeclampsia had platelet parameters and uric acid levels measured during pregnancy." | 3.67 | Platelets and uric acid in the prediction of preeclampsia. ( Bromham, DR; Brooks, JA; Fay, RA; Gebski, VJ, 1985) |
| "A prospective longitudinal study was conducted, looking at the changes in serum uric acid during pregnancy in women who were normotensive at initial presentation." | 3.66 | Serum uric acid as a marker of pregnancy-induced hypertension. ( Hickman, PE; Michael, CA; Potter, JM, 1982) |
| " The routine determination of uric acid concentration in serum seems to be of no great value for predicting pregnancy-induced hypertension, compared with the roll-over test or with the angiotensin sensitivity test; however, it gives an additional information (a) in pregnancy women with questionable gestosis, and (b) in the differential diagnosis of pregnancy-induced versus pre-existing essential hypertension." | 3.66 | [Methods for the early recognition of gestosis]. ( Kaulhausen, H; Oney, T, 1979) |
| "The authors have carried out research in 58 cases to see whether the findings of high uric acid levels in the blood are of prognostic value in all cases of arterial hypertension in pregnancy whatever the aetiology." | 3.66 | [The prognostic value of raised uric acid in the blood in arterial hypertension in pregnancy. 58 cases (author's transl)]. ( Cotteel, M; Delecour, M; Dequiedt, P; Leroy, JL; Potier, A; Puech, F; Tacquet, A, 1979) |
| "This study demonstrates that uric acid serum levels are of importance in the prognosis of pregnancy complicated by hypertension." | 3.66 | [The clinical significance of hyperuricemia for the prognosis of pregnancy toxemia]. ( Eisenbach, GM; Haeckel, R; Henkel, E; Riedel, H; Witzel, B, 1978) |
| "Preeclampsia is a hypertensive disorder of pregnancy and is due to abnormal placentation." | 3.01 | Fructose might be a clue to the origin of preeclampsia insights from nature and evolution. ( Ananth Karumanchi, S; Johnson, RJ; Kang, DH; Kojima, H; Kosugi, T; Kublickiene, K; Lanaspa, MA; Nakagawa, T; Rodriguez-Iturbe, B; Sanchez-Lozada, LG; Stenvinkel, P; Tolan, DR, 2023) |
| "Superimposed preeclampsia complicates about 20% of pregnancies in women with chronic hypertension and is associated with increased maternal and perinatal morbidity compared with preeclampsia alone." | 2.82 | Chronic hypertension and superimposed preeclampsia: screening and diagnosis. ( Kametas, NA; Nicolaides, KH; Nzelu, D, 2022) |
| "Preeclampsia is a multifactorial cardiovascular disorder of pregnancy." | 2.82 | The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis. ( Afrose, D; Chen, H; Hansbro, PM; Henessy, A; Liu, CC; McClements, L; Ranashinghe, A, 2022) |
| "Epidemiological characteristics of preeclampsia such as its uniqueness to humans and an increased incidence of preeclampsia in multiple pregnancies, increased body mass index, renal and hypertensive disease all have uric acid as their common denominator." | 2.71 | Hyperuricaemia and preeclampsia: is there a pathogenic link? ( Schackis, RC, 2004) |
| "The pregnancy was normal in 54% of patients in group A and 23% in group B (p less than 0." | 2.65 | [Controlled trial of preventive treatment of preeclampsia. Preliminary results]. ( Beaufils, M; Colau, JC; Donsimoni, R; Uzan, S, 1984) |
| "In most women with preeclampsia, renal plasma flow and glomerular filtration rate are at most only modestly decreased as a consequence of increased afferent arteriolar resistance and/or reduced ultrafiltration coefficient." | 2.44 | Renal function during normal pregnancy and preeclampsia. ( Conrad, KP; Jeyabalan, A, 2007) |
| "Purine inborn errors of metabolism (IEM) are serious hereditary disorders, which should be suspected in any case of neonatal fitting, failure to thrive, recurrent infections, neurological deficit, renal disease, self-mutilation and other manifestations." | 2.44 | Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions. ( Aquino Neto, FR; de Oliveira, ML; Gomes, LN; Oliveira, CP; Scalco, FB; Simoni, RE, 2007) |
| "Hyperuricemia is a common finding in preeclamptic pregnancies evident from early pregnancy." | 2.44 | Uric acid as a pathogenic factor in preeclampsia. ( Bainbridge, SA; Roberts, JM, 2008) |
| "The defect observed in preeclampsia is the lack of invasion of the trophoblast to the maternal arteries." | 2.40 | [Observations on pe-eclampsia-eclampsia and the advances in the evolution of some laboratory tests]. ( Arredondo Soberón, F; Ayala Barahona, T; Morgan, MA; Noguera Sánchez, MF, 1997) |
| "Preeclampsia is also characterized by increased free radical formation and elevated oxidative stress." | 2.39 | Hyperuricemia and xanthine oxidase in preeclampsia, revisited. ( Hubel, CA; Many, A; Roberts, JM, 1996) |
| "The signs and symptoms of preeclampsia are usually apparent at a relatively late stage in pregnancy (late second to early third trimester)." | 2.38 | Early detection of preeclampsia. ( Dekker, GA; Sibai, BM, 1991) |
| "The levels of CA 125 in mild and severe preeclampsia were (21." | 1.91 | Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023) |
| "Preeclampsia is one of the most severe diseases among the hypertensive disorders of pregnancy (HDP) and the leading cause of maternal and fetal morbidity and mortality." | 1.91 | Serum uric acid to creatinine ratio and risk of preeclampsia and adverse pregnancy outcomes. ( Agnoletti, D; Baracchi, A; Borghi, C; Degli Esposti, D; Montaguti, E; Piani, F; Scarduelli, S; Simonazzi, G; Tossetta, G; Verde, C, 2023) |
| "UPCR ≥ 0." | 1.91 | Withstanding the test of time: Morning versus afternoon/evening urine protein-to-creatinine ratios in preeclampsia. ( Fogel, J; Hong, P; Karrar, S, 2023) |
| "Clinical data of patients with preeclampsia were collected from the Medical Information Mart for Intensive Care (MIMIC)-IV database." | 1.91 | Uric acid as a mediator in the correlation between white blood cells and preeclampsia severity: a retrospective cohort study. ( He, CM; Hu, XY; Li, BJ; Zhu, TT, 2023) |
| "Hyperuricemia is a common laboratory finding in pregnant women compromised by preeclampsia." | 1.72 | Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System. ( Albrecht, C; Baumann, MU; Lüscher, BP; Stieger, B; Surbek, DV, 2022) |
| "The study consisted of 170 cases (84 preeclampsia and 86 control)." | 1.72 | Role of derived neutrophil-to-lymphocyte ratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal outcomes in pregnancies with preeclampsia. ( Altinboğa, O; Elbayiyev, S; Erol, A; Şenel, S; Tanaçan, A; Yakiştiran, B; Yücel, A, 2022) |
| "Hyperuricemia is a common feature in pregnancies compromised by pre-eclampsia, a pregnancy disease characterized by hypertension and proteinuria." | 1.72 | Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice. ( Baumann, MU; Lüscher, BP; Schoeberlein, A; Surbek, DV, 2022) |
| "The mean uric acid in women with preeclampsia was 6." | 1.72 | Association between maternal serum uric acid and preeclampsia. ( Fathi, L; Ghafarzadeh, M; Shakarami, A; Yari, F, 2022) |
| "Fifty consecutive women with mild preeclampsia, 50 consecutive women with severe preeclampsia, and 100 consecutive pregnant women with a gestational age-matched (±1 week) uncomplicated pregnancy were evaluated in a cross-sectional study." | 1.72 | Serum catestatin level is increased in women with preeclampsia. ( Bulut, H; Gök, K; Güralp, O; Hamzaoglu, K; Irmak, K; Makul, M; Malik, E; Oner, YO; Tüten, A; Tüten, N, 2022) |
| "Hyperuricemia is often associated with pre-eclampsia and when this occurs, fetal outcome may become worse." | 1.72 | Maternal serum uric acid: a reliable prognostic indicator of foetal outcome among pre-eclamptic patients in a low resource setting. ( Adebara, IO; Adeniyi, AA; Adewara, OE; Adeyemo, OT; Awoyinka, SB; Ayankunle, OM; Bakare, A; Jimoh, AK; Olumodeji, AM, 2022) |
| "The data regarding preeclampsia and its associated risk factors are scarce or limited in pregnant women in Bangladesh." | 1.62 | Prevalence of preeclampsia and the associated risk factors among pregnant women in Bangladesh. ( Ali, N; Barman, Z; Das Trisha, A; Hafsa, JM; Hasan, M; Miah, R; Mou, AD, 2021) |
| "14 severe preeclampsia, 48 mild preeclampsia and 79 patients with healthy pregnancy who presented to our obstetrics and gynecology clinic within one year were compared." | 1.62 | The role of cystatin C, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in the evaluation of kidney function in women with preeclampsia. ( Erten, Ö; Taşkömür, AT, 2021) |
| "Toxemia of pregnancy is a very dangerous disease for pregnant women." | 1.56 | Integrated EC-SERS Chip with Uniform Nanostructured EC-SERS Active Working Electrode for Rapid Detection of Uric Acid. ( Hsiao, HC; Huang, CY, 2020) |
| "We studied 1002 women with preeclampsia." | 1.51 | Soluble Endoglin As a Marker for Preeclampsia, Its Severity, and the Occurrence of Adverse Outcomes. ( Isordia-Salas, I; Jiménez-Trejo, LM; Leaños-Miranda, A; Navarro-Romero, CS; Ramírez-Valenzuela, KL; Sillas-Pardo, LJ, 2019) |
| "Preeclampsia is defined as hypertension (systolic pressure ≥140 mmHg or diastolic pressure ≥90 mmHg) after week 20 of gestation with one or more of the following symptoms: proteinuria, organ dysfunction (including renal, hepatologic, hematologic or neurological complications) and in case of stagnation of fetal development." | 1.51 | Uric Acid Values Along with Doppler Sonography Findings as a Tool for Preeclampsia Screening. ( Dzihic, E; Iglica, A; Mahmutbegovic, E; Medjedovic, E; Muftic, A; Rama, A; Suljevic, A, 2019) |
| "Women were grouped according to status (preeclampsia or normotensive), and a logistic regression analysis was used to determine the relationship between serum uric acid levels and adverse outcomes." | 1.51 | Predictive value of serum uric acid levels for adverse perinatal outcomes in preeclampsia. ( Cho, NJ; Kim, YS; Lee, EY; Ryu, A, 2019) |
| "Uric acid levels in PE were significantly higher than in control groups (p < 0." | 1.48 | Strontium and its role in preeclampsia. ( Álvarez Menéndez, FV; Barneo-Caragol, C; Lequerica-Fernández, P; Martínez-Morillo, E; Rodríguez-González, S; Vega-Naredo, I, 2018) |
| "Although gestational hypertension (GH) is thought to be different from preeclampsia (PE), in Japan GH and PE are usually treated as the same disease (i." | 1.46 | Comparison of Kidney Function between Gestational Hypertension and Preeclampsia. ( Eguchi, T; Eto, E; Hayata, K; Hiramatsu, Y; Maki, J; Masuyama, H; Mitsui, T; Nobumoto, E; Tamada, S, 2017) |
| "A total of 877 women with preeclampsia at presentation and 580 normotensive pregnancies were retrospectively recruited from January 2009 to May 2014." | 1.43 | Serum uric acid may not be involved in the development of preeclampsia. ( Chen, Q; Lau, S; Shen, F; Tong, M; Wei, J; Zhao, J; Zhao, M, 2016) |
| "All findings of preeclampsia appear as the clinical consequences of diffuse endothelial dysfunction." | 1.43 | Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study. ( Ates, S; Bademler, N; Batmaz, G; Dane, B; Gursu, M; Karadag, S; Kilic, E; Ozel, A; Ozturk, S; Sumnu, A; Sumnu, G; Yildirim, ZK, 2016) |
| "106 women were classified into preeclampsia group (n = 40) and normotensive group (n = 66)." | 1.43 | Serum nitrate and NOx levels in preeclampsia are higher than in normal pregnancy. ( Acauan Filho, BJ; Antonello, IC; Ogando, PB; Pinheiro da Costa, BE; Poli-de-Figueiredo, CE; Vieira, MC, 2016) |
| "The levels of uric acid in women with preeclampsia were measured." | 1.43 | Increased expression of high mobility group box 1 (HMGB1) in the cytoplasm of placental syncytiotrophoblast from preeclamptic placentae. ( Chamley, L; Chen, Q; Shen, F; Tong, M; Wei, J; Yin, YX; Zhao, M, 2016) |
| "Preeclampsia is a specific disorder of human pregnancy that is associated with hyperuricemia and higher levels of pro-inflammatory cytokines." | 1.43 | Elevated circulatingadenosine deaminase activity in women with preeclampsia: association with pro-inflammatory cytokine production and uric acid levels. ( Bannwart-Castro, CF; Borges, VT; Giorgi, VS; Peraçoli, JC; Peraçoli, MT; Romão-Veiga, M; Sartori, MS; Witkin, SS, 2016) |
| "The precise etiopathogenesis of preeclampsia (PE) still remains enigmatic." | 1.43 | Second trimester amniotic fluid uric acid, potassium, and cysteine to methionine ratio levels as possible signs of early preeclampsia: A case report. ( Athanasiadis, AP; Biliaderis, CG; Fotiou, M; Koulourida, V; Masoura, S; Menexes, G; Michaelidou, AM; Tarlatzis, BC, 2016) |
| "Uric acid crystals may activate an intracellular complex called inflammasome, which is important for processing and release of inflammatory cytokines." | 1.42 | Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia. ( Araújo, JP; Borges, VT; de Oliveira, L; Matias, ML; Nunes, PR; Peraçoli, JC; Peraçoli, MT; Ribeiro, VR; Romão, M; Weel, IC, 2015) |
| "Uric acid Z score was associated with adverse perinatal outcome (OR 1." | 1.40 | Uric Acid as a predictor of adverse maternal and perinatal outcomes in women hospitalized with preeclampsia. ( Brown, M; Côté, AM; Livingston, JR; Magee, LA; Payne, B; Roberts, JM; von Dadelszen, P, 2014) |
| "Uric acid levels were similar in both groups during the first half of gestation." | 1.40 | [Serum uric acid levels and risk of developing preeclampsia]. ( Balconi, SM; Corominas, AI; Damiano, AE; Maskin, B; Palermo, M, 2014) |
| "Uric acid is a terminal metabolite of the degradation of nucleotides, which increases their blood levels in patients with preeclampsia increasing its synthesis by damage and death of trophoblastic cells and proliferation." | 1.40 | Serum uric acid level in normal pregnant and preeclamptic ladies: a comparative study. ( Khatiwada, B; Pradhan, P; Pramanik, T, 2014) |
| "The presence of preeclampsia also correlated with greater supplemental uterotonic agent use (P=0." | 1.39 | Serum uric acid as a novel marker for uterine atony and post-spinal vasopressor use during cesarean delivery. ( Kovacheva, VP; Soens, MA; Tsen, LC, 2013) |
| "We present a case of parathyroid carcinoma in pregnancy presenting with pre-eclampsia at 32 weeks' gestation." | 1.38 | Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy. ( Beer, I; Conaglen, JV; Elston, MS; Gill, AJ; Marsh, D; Meyer-Rochow, GY; Paul, RG; Wolmarans, L, 2012) |
| "Uric acid is known to be elevated in preeclampsia." | 1.38 | Admission uric acid levels and length of expectant management in preterm preeclampsia. ( Bond, B; Craigo, SD; Norwitz, ER; Paulus, JK; Strohsnitter, WC; Urato, AC, 2012) |
| "Twenty-eight women with mild preeclampsia and 22 with severe preeclampsia at Nanfang Hospital, Southern Medical University between October 2010 and June 2011 were recruited." | 1.38 | [Diagnostic value of radom spot albuminuria to creatinine ratio in women with preeclampsia]. ( Gao, YF; Huang, QT; Leng, LZ; Wang, W; Wang, Y; Wang, ZJ; Yu, YH; Zhong, M, 2012) |
| "(5) In preeclampsia, serum LCN-2 level significant associated with 24 hours total urinary protein and uric acid (r = 0." | 1.38 | [Correlation of lipocalin-2 and its receptor expressions with preeclampsia]. ( Cao, WH; Chen, WP; Li, J; Ye, YH, 2012) |
| "Fifty patients with mild preeclampsia, 50 patients with severe preeclampsia, and 50 healthy normotensive pregnant women (control group) were selected from those admitted to the delivery unit." | 1.37 | Elevated serum-soluble Fas in preeclampsia: correlation with clinical, laboratory, and Doppler parameters. ( El-Mazny, A; El-Sherbiny, W; Soliman, A, 2011) |
| "Because preeclampsia is associated with placental immune⁄ inflammatory dysregulation, we sought to determine in the trophoblast, the presence of the Nalp3 inflammasome, and the effect of MSU on its activation." | 1.37 | Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia. ( Abrahams, VM; Boeras, C; Guller, S; Kavathas, PB; Mulla, MJ; Myrtolli, K; Norwitz, ER; Potter, J; Sfakianaki, AK; Tadesse, S, 2011) |
| "(1) The median levels of CRP in severe preeclampsia (10." | 1.37 | [Association between plasma levels of soluble leukocyte differentiation antigens CD₄₀/CD₄₀ ligand and kidney damage in preeclamptic patients]. ( Cui, XN; Li, C; Qin, W; Ye, YH; Zhan, Y, 2011) |
| "Leptin has a promising future as a valuable marker to identity women with a high risk for preeclampsia." | 1.36 | Leptin levels and antihypertensive treatment in preeclampsia. ( Gungor, T; Kanat-Pektas, M; Mollamahmutoglu, L; Sucak, A, 2010) |
| "Medical records of patients with preeclampsia and patients with PIH who delivered at term between January 2003 and December 2004 were reviewed." | 1.35 | Retinopathy in preeclampsia: association with birth weight and uric acid level. ( Gupta, A; Kaliaperumal, S; Rao, VA; Setia, S; Suchi, ST, 2008) |
| "Triuret was also found to be elevated in the urine of subjects with preeclampsia, a pregnancy-specific hypertensive syndrome that is associated with oxidative stress, whereas very little triuret is produced in normal healthy volunteers." | 1.35 | Reactions of peroxynitrite with uric acid: formation of reactive intermediates, alkylated products and triuret, and in vivo production of triuret under conditions of oxidative stress. ( Angerhofer, A; Gersch, C; Henderson, GN; Imaram, W; Johnson, RJ; Karumanchi, SA; Kim, KM; Palii, SP, 2009) |
| "Preeclampsia is referred to as the "disease of the theories" because of the multiple hypotheses proposed to explain is occurrence." | 1.35 | Insulin resistance and C-reactive protein in preeclampsia. ( Kutlesić, R; Milosavljević, M; Popović, J; Stefanović, M; Tubić-Pavlović, A; Vukomanović, P, 2009) |
| "Preeclampsia is one of the most serious complications of pregnancy." | 1.33 | Measurement of the total antioxidant response in preeclampsia with a novel automated method. ( Erel, O; Harma, M, 2005) |
| "Twenty-six transfusions (5." | 1.33 | Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome. A study in 453 consecutive pregnancies. ( Codaccioni, X; Coudoux, E; Deruelle, P; Ego, A; Houfflin-Debarge, V; Subtil, D, 2006) |
| "Women with preeclampsia had significantly lower calciuria than normotensive patients (1." | 1.33 | Calciuria and preeclampsia: a case-control study. ( Brédent-Bangou, J; David, S; Janky, E; Szmidt-Adjidé, V; Vendittelli, F, 2006) |
| "Renal function in women with severe preeclampsia was significantly impaired and highly correlated with systolic or diastolic blood pressure." | 1.33 | The correlation between renal function and systolic or diastolic blood pressure in severe preeclamptic women. ( Chen, DC; Chuang, J; Seow, KM; Tang, MH; Wang, YY, 2005) |
| "The serum cTn I of the preeclampsia group was 0." | 1.33 | [Changes of serum cardiotrophin I and cystatin C in preeclampsia and clinical significance thereof]. ( Dong, MY; He, J; Lu, DH; Wang, HZ; Wang, ZP; Yang, XF, 2006) |
| "To determine whether a rat model of preeclampsia includes features consistent with HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome." | 1.32 | Evaluation of a rat model of preeclampsia for HELLP syndrome characteristics. ( Bennett, WA; Cockrell, KL; Granger, JP; Isler, CM; Martin, JN; Morrison, JC; Rinewalt, AN, 2003) |
| "Uric acid was also evaluated and used as an indicator of the severity of the disease." | 1.32 | Neutrophil activation and C-reactive protein concentration in preeclampsia. ( Belo, L; Caslake, M; Cooney, J; Pereira-Leite, L; Quintanilha, A; Rebelo, I; Santos-Silva, A, 2003) |
| "Women with chronic hypertension are at increased risk for superimposed preeclampsia." | 1.32 | A prediction model for superimposed preeclampsia in women with chronic hypertension during pregnancy. ( August, P; Cook, EF; Helseth, G; Sison, C, 2004) |
| "Nineteen pregnancies with preeclampsia, 16 with diabetic preeclampsia and 29 control pregnancies were analyzed with regards to maternal total glutathione." | 1.31 | Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes. ( Kharb, S, 2000) |
| "To better direct screening for preeclampsia, we describe the result trends of the laboratory tests used in the workup of preeclampsia at our institution." | 1.31 | Laboratory testing for preeclampsia: result trends and screening recommendations. ( Kopelman, JN; Macri, C; Ries, A, 2000) |
| "Pre-eclampsia and eclampsia are associated with higher levels of cord blood erythropoietin." | 1.31 | Estimation of cord blood erythropoietin in pre-eclampsia and eclampsia. ( Dhawan, V; Ganguly, NK; Gupta, G; Gupta, I; Suri, V, 2000) |
| "Etiology of preeclampsia is still largely unraveled and treatment is syndrome specific." | 1.31 | [Twin pregnancy and preeclampsia]. ( Leszczyńska-Gorzelak, B; Oleszczuk, JJ; Szymczyk, G, 2000) |
| "The incidence of preeclampsia was significantly associated with increasing urinary albumin excretion rate, primiparity, and ambulatory blood pressure." | 1.31 | Ambulatory blood pressure as predictor of preeclampsia in diabetic pregnancies with respect to urinary albumin excretion rate and glycemic regulation. ( Klebe, JG; Klebe, TM; Lauszus, FF; Lousen, T; Rasmussen, OW, 2001) |
| "Forty-four women (29%) developed preeclampsia (preeclampsia group) at 33." | 1.30 | Elevation of the serum uric acid level preceding the clinical manifestation of preeclampsia in twin pregnancies. ( Koike, T; Kuwata, T; Minakami, H; Ogawa, S; Sato, I; Takayama, T, 1997) |
| "Preeclampsia was defined as a persistent blood pressure > or =140/90 mmHg, and proteinuria, or elevated liver enzymes, thrombocytopenia, or eclamptic seizure." | 1.30 | Maternal serum uric acid levels in preeclamptic women with multiple gestations. ( Chou, K; Chung, YK; Copel, JA; Hsu, CD; Lee, IS, 1997) |
| "Previous studies of preeclampsia have only measured total glutathione levels." | 1.30 | Erythrocyte glutathione balance and membrane stability during preeclampsia. ( McKillop, J; Reglinski, J; Smith, WE; Spickett, CM; Walker, JJ; Wilson, R, 1998) |
| "Class 3 HELLP syndrome is considered a clinically significant transitional group." | 1.30 | The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999) |
| "This may be a pathogenetic factor in preeclampsia and may contribute to the excess cardiovascular morbidity among women with prior preeclampsia." | 1.30 | Evidence of a state of increased insulin resistance in preeclampsia. ( Kaaja, R; Laakso, M; Laivuori, H; Tikkanen, MJ; Ylikorkala, O, 1999) |
| "The mechanism of hyperuricemia in preeclampsia remains unknown." | 1.30 | Placental pathologies are not associated with hyperuricemia in preeclamptic pregnancies. ( Hsu, CD; Lee, IS, 1999) |
| "With or without preeclampsia, women carrying twins have significantly higher serum uric acid levels than their singleton counterparts, which suggests a need for separate normative values for twin gestations." | 1.29 | Maternal serum uric acid levels in twin gestations. ( Bianculli, KW; Fischer, RL; Hediger, ML; Scholl, TO, 1995) |
| "To investigate the possible effect of preeclampsia on erythropoietin metabolism, we measured plasma and urine erythropoietin concentrations and complete blood count in 19 women with preeclampsia and nine healthy gravidas." | 1.28 | Erythropoietin in preeclampsia. ( Gonzales, E; Kaupke, CJ; Powers, DR; Vaziri, ND, 1991) |
| "However, toxemia of pregnancy have relapsed in the case with low u-Ca excretion of less than 100 mg/day during the second pregnancy." | 1.28 | [Urinary calcium excretion in toxemia of pregnancy]. ( Aoki, J; Fujinami, T; Morozumi, K; Oikawa, T; Sato, K; Suganuma, T; Yoshida, A, 1989) |
| "Renal involvement associated with preeclampsia is well investigated, especially from the aspect of glomerular lesion and coagulation." | 1.27 | [Preeclampsia and tubular dysfunction]. ( Morozumi, K; Shinmura, I; Yagami, Y; Yoshida, A, 1987) |
| "Twelve of 21 patients with severe toxemia of pregnancy showed high PRL levels in zone A (greater than mean value + 1 S." | 1.27 | Prolactin in severe toxemia of pregnancy. ( Miyakawa, I; Mori, N; Sakata, M; Taniyama, K; Yamaguchi, M, 1986) |
| "10 patients with severe preeclampsia showed changes in both coagulation and renal function when compared with 13 normotensive controls." | 1.26 | Clinical relevance of coagulation and renal changes in pre-eclampsia. ( Dunlop, W; Hill, LM; Jones, P; Landon, MJ; Oxley, A, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 133 (33.25) | 18.7374 |
| 1990's | 62 (15.50) | 18.2507 |
| 2000's | 77 (19.25) | 29.6817 |
| 2010's | 86 (21.50) | 24.3611 |
| 2020's | 42 (10.50) | 2.80 |
| Authors | Studies |
|---|---|
| Nori, W | 2 |
| Ali, AI | 1 |
| Mou, AD | 1 |
| Barman, Z | 1 |
| Hasan, M | 1 |
| Miah, R | 1 |
| Hafsa, JM | 1 |
| Das Trisha, A | 1 |
| Ali, N | 1 |
| de Mendonça, ELSS | 1 |
| da Silva, JVF | 1 |
| Mello, CS | 1 |
| de Oliveira, ACM | 1 |
| Hamed, RM | 1 |
| Roomi, AB | 1 |
| Akram, W | 1 |
| Kametas, NA | 1 |
| Nzelu, D | 1 |
| Nicolaides, KH | 1 |
| Lüscher, BP | 5 |
| Albrecht, C | 2 |
| Stieger, B | 1 |
| Surbek, DV | 5 |
| Baumann, MU | 5 |
| Jakes, AD | 1 |
| Cox, M | 1 |
| Drane, S | 1 |
| Johnson, A | 1 |
| Yakiştiran, B | 1 |
| Tanaçan, A | 1 |
| Altinboğa, O | 1 |
| Erol, A | 1 |
| Şenel, S | 1 |
| Elbayiyev, S | 1 |
| Yücel, A | 1 |
| Ohamadike, O | 1 |
| Lim, SL | 1 |
| Siegel, A | 1 |
| Zemtsov, G | 1 |
| Kuller, JA | 1 |
| Dotters-Katz, S | 1 |
| Chen, L | 1 |
| Pi, Y | 1 |
| Chang, K | 1 |
| Luo, S | 1 |
| Peng, Z | 1 |
| Chen, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women[NCT05622838] | 160 participants (Anticipated) | Observational | 2022-12-31 | Not yet recruiting | |||
| A Three-arm, Multicenter, Open-label Randomized Controlled Trial of Hydroxychloroquine and Low-dose Prednisone on Recurrent Spontaneous Abortion With Undifferentiated Connective Tissue Diseases: Protocol for the Immunosuppressant Regimens for Living FEtus[NCT03671174] | 420 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting | |||
| Microcirculatory and Tissue and Cerebral Oxygenation Differences Between Preeclampsia and Normal Pregnancy: An Observation Study[NCT02351583] | 0 participants (Actual) | Observational | 2015-01-01 | Withdrawn (stopped due to equipment difficulties) | |||
| The Clinical Utility of the Congo-Red Dot Test for Diagnosis and Early Prediction of Preeclampsia During Pregnancy[NCT02455544] | 346 participants (Actual) | Observational [Patient Registry] | 2014-08-31 | Completed | |||
| Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women With Preeclampsia[NCT04298034] | Phase 3 | 300 participants (Anticipated) | Interventional | 2020-07-17 | Recruiting | ||
| Genetic, Laboratory and Clinical Factors Associated With Low-dose Aspirin Failure in the Prevention of Preeclampsia- An Exploratory Protocol[NCT05709483] | Early Phase 1 | 130 participants (Anticipated) | Interventional | 2023-04-13 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
43 reviews available for uric acid and Pre-Eclampsia
| Article | Year |
|---|---|
Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
Topics: Aldosterone; Angiogenic Proteins; Biomarkers; Chronic Disease; Cytokines; Female; Humans; Hypertensi | 2022 |
Hypertensive Disorders of Pregnancy: Common Clinical Conundrums.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; P | 2022 |
The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis.
Topics: Biomarkers; Female; Humans; Oxidative Stress; Pre-Eclampsia; Pregnancy; Serum Albumin; Uric Acid | 2022 |
Fructose might be a clue to the origin of preeclampsia insights from nature and evolution.
Topics: Female; Fructose; Humans; Hypoxia; Placenta; Pre-Eclampsia; Pregnancy; Uric Acid | 2023 |
Uric acid and risk of pre-eclampsia: results from a large case-control study and meta-analysis of prospective studies.
Topics: Blood Pressure; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; | 2023 |
Inflammation-The role of ATP in pre-eclampsia.
Topics: Adenosine Triphosphate; Female; Humans; Inflammation; Interleukin-1; Pre-Eclampsia; Pregnancy; Recep | 2020 |
The prognostic role of serum uric acid levels in preeclampsia: A meta-analysis.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Prognosis; Prospective Studies; Uric Acid | 2020 |
Predictive value of serum uric acid levels for adverse maternal and perinatal outcomes in pregnant women with high blood pressure. A systematic review and meta-analysis.
Topics: Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnant | 2020 |
The Role of Uric Acid in Preeclampsia: Is Uric Acid a Causative Factor or a Sign of Preeclampsia?
Topics: Biomarkers; Female; Fetal Growth Retardation; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 2018 |
[Uric acid and purine plasma levels as plausible markers for placental dysfunction in pre-eclampsia].
Topics: Biomarkers; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Purines; Uric Acid | 2013 |
The involvement of uric acid in the pathogenesis of preeclampsia.
Topics: Female; Humans; Hyperuricemia; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Uric Acid | 2015 |
Accuracy of serum uric acid as a predictive test for maternal complications in pre-eclampsia: bivariate meta-analysis and decision analysis.
Topics: Decision Support Techniques; Female; HELLP Syndrome; Humans; Labor, Induced; Pre-Eclampsia; Predicti | 2009 |
Could uric acid have a pathogenic role in pre-eclampsia?
Topics: Female; Humans; Hyperuricemia; Pre-Eclampsia; Pregnancy; Risk Factors; Uric Acid | 2010 |
[Role of uric acid in preeclampsia-eclampsia].
Topics: Animals; Causality; Cesarean Section; Eclampsia; Endothelium, Vascular; Female; Humans; Hypertension | 2011 |
The management of pre-eclampsia: what we think we know.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Proteinuria; Uric Acid | 2012 |
Serum uric acid and pre-eclampsia: an update.
Topics: Animals; Female; Humans; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Pregnancy Outcom | 2012 |
[Influence of pregnancy on serum uric acid].
Topics: Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Infant, Newborn; Pre-Eclampsia; Pregnancy | 2003 |
[Hyperuricemia in preeclampsia].
Topics: Biomarkers; Female; Humans; Hyperuricemia; Kidney; Placenta; Pre-Eclampsia; Predictive Value of Test | 2003 |
Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link.
Topics: Endothelium, Vascular; Female; Humans; Hyperuricemia; Models, Biological; Pre-Eclampsia; Pregnancy; | 2004 |
Uric acid, endothelial dysfunction and pre-eclampsia.
Topics: Animals; Endothelium, Vascular; Female; Humans; Hyperuricemia; Pre-Eclampsia; Pregnancy; Uric Acid | 2004 |
Hypertension during pregnancy: a disorder begging for pathophysiological support.
Topics: Eclampsia; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; | 2005 |
Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review.
Topics: Biomarkers; Cesarean Section; Female; Fetal Growth Retardation; HELLP Syndrome; Humans; Hypertension | 2006 |
Accuracy of serum uric acid determination in predicting pre-eclampsia: a systematic review.
Topics: Female; Humans; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Uric Acid | 2006 |
Renal function during normal pregnancy and preeclampsia.
Topics: Angiogenic Proteins; Animals; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidney; Kid | 2007 |
Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions.
Topics: Biomarkers; Diabetes Insipidus; Female; Humans; Kidney Diseases; Metabolism, Inborn Errors; Polycyst | 2007 |
Uric acid as a pathogenic factor in preeclampsia.
Topics: Female; Humans; Hyperuricemia; Placenta; Pre-Eclampsia; Pregnancy; Uric Acid | 2008 |
Hyperuricemia and xanthine oxidase in preeclampsia, revisited.
Topics: Female; Humans; Kidney; Pre-Eclampsia; Pregnancy; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidas | 1996 |
[Uric acid and pre-eclampsia].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Prognosis; Uric Acid | 1997 |
[Observations on pe-eclampsia-eclampsia and the advances in the evolution of some laboratory tests].
Topics: Adult; Calcium; Capillary Permeability; Chorionic Gonadotropin; Eclampsia; Female; Humans; Hypertens | 1997 |
[Severe maternal complications associated with pre-eclampsia: an almost forgotten pathology?].
Topics: Abruptio Placentae; Adult; Anemia, Hemolytic; Case-Control Studies; Cesarean Section; Critical Care; | 2001 |
Assessment of renal functions in hypertensive pregnancies.
Topics: Acute Kidney Injury; Female; Fetal Death; Humans; Hypertension; Kidney; Kidney Glomerulus; Kidney Tu | 1977 |
[The kidney and uric acid].
Topics: Acute Kidney Injury; Female; Gout; Humans; Hypertension; Kidney; Kidney Calculi; Kidney Diseases; Ki | 1975 |
[Selected phsiopathological and clinical aspects of purine metabolism].
Topics: Alkalosis, Respiratory; Diabetes Mellitus; Diuresis; Female; Fructose Intolerance; Glomerular Filtra | 1976 |
Early detection of preeclampsia.
Topics: Biomarkers; Blood Coagulation Factors; Blood Pressure; Calcium; Epoprostenol; Female; Humans; Platel | 1991 |
Predicting preeclampsia.
Topics: Angiotensin II; Antithrombin III; Atrial Natriuretic Factor; beta-Thromboglobulin; Blood Pressure; B | 1990 |
[Significance of blood uric acid determination. Review of the literature].
Topics: Female; Humans; Kidney Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Prognosis; Uric | 1990 |
Uric acid in pregnancy and preeclampsia: an alternative hypothesis.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Trophoblasts; Uric Acid | 1990 |
Pre-eclampsia and related complications of pregnancy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Coagulation Disorders; Catecholamines; Diagnosis, Differen | 1970 |
Influence of the kidney upon urate homeostasis in health and disease.
Topics: Acute Kidney Injury; Female; Glomerular Filtration Rate; Gout; Homeostasis; Humans; Hypertension; Hy | 1974 |
[Effect of purine metabolism on renal function].
Topics: Alcoholic Intoxication; Female; Humans; Kidney; Lesch-Nyhan Syndrome; Male; Physical Exertion; Pre-E | 1974 |
Liver-kidney interrelation in pregnancy and toxemia.
Topics: Acute Kidney Injury; Ammonia; Erythrocytes; Estrogens; Female; Glomerular Filtration Rate; Glucocort | 1968 |
Hypertension and renal disease in pregnancy.
Topics: Adrenal Cortex Hormones; Animals; Biopsy; Body Weight; Diet, Sodium-Restricted; Eclampsia; Edema; Fe | 1971 |
Diuretics. II. Clinical considerations.
Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I | 1971 |
15 trials available for uric acid and Pre-Eclampsia
| Article | Year |
|---|---|
Calcium supplementation during pregnancy for preventing hypertensive disorders is not associated with changes in platelet count, urate, and urinary protein: a randomized control trial.
Topics: Adolescent; Adult; Calcium; Dietary Supplements; Double-Blind Method; Female; Humans; Platelet Count | 2008 |
Serum concentrations of CA-125 in normal and preeclamptic pregnancies.
Topics: Adult; Analysis of Variance; Biomarkers; Birth Weight; Blood Pressure; CA-125 Antigen; Female; Fetal | 2011 |
Nitric oxide, lipid peroxides, and uric acid levels in pre-eclampsia and eclampsia.
Topics: Adult; Eclampsia; Erythrocytes; Female; Humans; Lipid Peroxides; Malondialdehyde; Nitric Oxide; Pre- | 2004 |
Hyperuricaemia and preeclampsia: is there a pathogenic link?
Topics: Adult; Blood Pressure; Creatine; Female; Humans; Hyperuricemia; Platelet Count; Pre-Eclampsia; Pregn | 2004 |
Oncotic therapy in management of preeclampsia.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dextrans; Female; Fetal Blood; Fetal Growth Retardat | 2006 |
[Controlled trial of preventive treatment of preeclampsia. Preliminary results].
Topics: Adult; Aspirin; Blood Volume; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardati | 1984 |
Total renin in pre-eclampsia.
Topics: Adult; Alanine Transaminase; Biomarkers; Blood Proteins; Female; Humans; Pre-Eclampsia; Pregnancy; R | 1995 |
Levels of erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, G6PD activity & plasma urate in patients of pregnancy induced hypertension.
Topics: Adult; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glutathione; Humans; Malondialdehyde; O | 1994 |
Antioxidants in the treatment of severe pre-eclampsia: an explanatory randomised controlled trial.
Topics: Adolescent; Adult; Allopurinol; Antioxidants; Ascorbic Acid; Double-Blind Method; Drug Monitoring; D | 1997 |
Failure of serum beta2-microglobulin levels as an early marker of preeclampsia.
Topics: Adult; beta 2-Microglobulin; Biomarkers; Case-Control Studies; Creatinine; Female; Humans; Pre-Eclam | 2000 |
Total free radical trapping antioxidant potential in pre-eclampsia.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Biomarkers; Female; Free Radicals; Humans; Lipid Per | 2000 |
Changes in urinary excretion of six biochemical parameters in normotensive pregnancy and preeclampsia.
Topics: Adult; Albuminuria; beta 2-Microglobulin; Biopsy; Blood Urea Nitrogen; Capillaries; Creatinine; Endo | 2002 |
Plasma-urate measurements in predicting fetal death in hypertensive pregnancy.
Topics: Blood Pressure; Chronic Disease; Female; Fetal Death; Gestational Age; Glomerular Filtration Rate; H | 1976 |
Dietary sodium chloride in pregnant hypertensive patients: a preliminary report.
Topics: Clinical Trials as Topic; Diet; Female; Humans; Hypertension; Placebos; Pre-Eclampsia; Pregnancy; Pr | 1976 |
Prospective controlled study of early antiplatelet therapy in prevention of preeclampsia.
Topics: Adult; Aspirin; Clinical Trials as Topic; Dipyridamole; Female; Fetal Growth Retardation; Humans; Pa | 1986 |
342 other studies available for uric acid and Pre-Eclampsia
| Article | Year |
|---|---|
Maternal alpha-1-antitrypsin as a noval marker for growth restriction in pre-eclampsia.
Topics: Female; Fetal Growth Retardation; Fetal Weight; Fetus; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 2021 |
Prevalence of preeclampsia and the associated risk factors among pregnant women in Bangladesh.
Topics: Adolescent; Adult; Alanine Transaminase; Antihypertensive Agents; Bangladesh; Cholesterol; Cohort St | 2021 |
Serum uric acid levels associated with biochemical parameters linked to preeclampsia severity and to adverse perinatal outcomes.
Topics: Cross-Sectional Studies; Female; Humans; Hyperuricemia; Infant, Newborn; Infant, Newborn, Diseases; | 2022 |
Alpha-1antitrypsin in pre-eclampsia; from a clinical perspective.
Topics: Blood Pressure; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnant Women; Uric | 2021 |
Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System.
Topics: Animals; Female; Glucose Transport Proteins, Facilitative; Humans; Hyperuricemia; Mice; Mice, Knocko | 2022 |
Reducing laboratory costs through rational testing in suspected pre-eclampsia.
Topics: Costs and Cost Analysis; Female; gamma-Glutamyltransferase; Humans; Infant, Newborn; Pre-Eclampsia; | 2022 |
Role of derived neutrophil-to-lymphocyte ratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal outcomes in pregnancies with preeclampsia.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Case-Control Studies; Creatinine; Fem | 2022 |
Screening models combining maternal characteristics and multiple markers for the early prediction of preeclampsia in pregnancy: a nested case-control study.
Topics: 5'-Nucleotidase; Alanine; alpha-L-Fucosidase; Aspartate Aminotransferases; Biomarkers; Case-Control | 2022 |
Evaluation of serum uric acid and liver function tests among pregnant women with and without preeclampsia at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
Topics: Alanine Transaminase; Biomarkers; Cross-Sectional Studies; Ethiopia; Female; Hospitals; Humans; Live | 2022 |
Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia.
Topics: Acute-Phase Proteins; Biomarkers; Female; Humans; Ischemia; Lipocalin-2; Lipocalins; Pre-Eclampsia; | 2023 |
Maternal tumour necrosis factor-alpha levels in preeclamptic pregnancies in Lagos, South-West Nigeria.
Topics: Case-Control Studies; Cross-Sectional Studies; Female; Humans; Nigeria; Pre-Eclampsia; Pregnancy; Pr | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice.
Topics: Animals; Blood Pressure; Female; Humans; Hypertension; Hyperuricemia; Mice; Phenotype; Pre-Eclampsia | 2022 |
Association of first trimester serum uric acid with preeclampsia: an observational cohort study with propensity score matching.
Topics: Cohort Studies; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Firs | 2023 |
Elevated Serum Uric Acid Is Associated With Gestational Diabetes Mellitus: An Observational Cohort Study.
Topics: Cohort Studies; Diabetes, Gestational; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pr | 2023 |
An elevation in serum uric acid precedes the development of preeclampsia.
Topics: Cohort Studies; Female; Humans; Hyperuricemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; | 2023 |
Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan.
Topics: C-Reactive Protein; CA-125 Antigen; Case-Control Studies; Female; Humans; Inflammation Mediators; Ne | 2023 |
Serum uric acid to creatinine ratio and risk of preeclampsia and adverse pregnancy outcomes.
Topics: Creatinine; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Pre-Eclampsia; Pregnan | 2023 |
Uric acid to creatinine ratio as a novel predictor of preeclampsia development and severity: Erratum.
Topics: Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Risk Factors; Uric Acid | 2023 |
Withstanding the test of time: Morning versus afternoon/evening urine protein-to-creatinine ratios in preeclampsia.
Topics: Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Proteinuria; Retrospective Studies; Uric Acid | 2023 |
Role of neutrophil / lymphocyte ratio, uric acid / albumin ratio and uric acid / creatinine ratio as predictors to severity of preeclampsia.
Topics: Albumins; Biomarkers; Creatinine; Cross-Sectional Studies; Female; Humans; Lymphocytes; Neutrophils; | 2023 |
Uric acid as a mediator in the correlation between white blood cells and preeclampsia severity: a retrospective cohort study.
Topics: Creatinine; Female; Humans; Leukocytes; Pre-Eclampsia; Pregnancy; Retrospective Studies; Uric Acid | 2023 |
Serum Uric Acid Measurement in Women With Hypertensive Disorders of Pregnancy.
Topics: Adult; Female; Humans; Hypertension, Pregnancy-Induced; Pre-Eclampsia; Pregnancy; Risk Factors; Uric | 2019 |
Soluble Endoglin As a Marker for Preeclampsia, Its Severity, and the Occurrence of Adverse Outcomes.
Topics: Adult; Biomarkers; Birth Weight; Blood Pressure; Creatinine; Endoglin; Female; Gestational Age; Huma | 2019 |
Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia.
Topics: Alternative Splicing; Electrophysiology; Female; Glucose Transport Proteins, Facilitative; Humans; H | 2019 |
Uric acid levels in gestational hypertensive women predict preeclampsia and outcome of small-for-gestational-age infants.
Topics: Female; Humans; Hypertension, Pregnancy-Induced; Infant; Infant, Newborn; Infant, Small for Gestatio | 2021 |
Investigating the diagnostic capacity of uric acid in the occurrence of preeclampsia.
Topics: Adult; Biomarkers; Body Weight; Case-Control Studies; Cohort Studies; Female; Humans; Linear Models; | 2020 |
Uric Acid Values Along with Doppler Sonography Findings as a Tool for Preeclampsia Screening.
Topics: Adult; Female; Humans; Mass Screening; Pre-Eclampsia; Pregnancy; Prospective Studies; Ultrasonograph | 2019 |
Gene polymorphisms of uric acid are associated with pre-eclampsia in South Africans of African ancestry.
Topics: Adult; Alleles; Black People; Case-Control Studies; Female; Genetic Predisposition to Disease; Genot | 2020 |
Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Biomarkers; Blood Pr | 2020 |
Association between maternal serum uric acid and preeclampsia.
Topics: Blood Pressure; Female; Gestational Age; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 2022 |
Association of Maternal Hyperuricemia with Post-Spinal Hypotension in Pre-Eclamptic Parturients Undergoing Emergency Cesarean Delivery: a Prospective Observational Study.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Biomarkers; Blood Pressure; Cesarean Section; Em | 2021 |
Foetal and maternal outcomes in hyperuricaemia pre-eclampsia patients in Hospital Universiti Sains Malaysia.
Topics: Adult; Female; Humans; Hyperuricemia; Infant, Low Birth Weight; Infant, Newborn; Kidney Function Tes | 2021 |
Integrated EC-SERS Chip with Uniform Nanostructured EC-SERS Active Working Electrode for Rapid Detection of Uric Acid.
Topics: Electrodes; Female; Gold; Humans; Metal Nanoparticles; Pre-Eclampsia; Pregnancy; Spectrum Analysis, | 2020 |
Role of Calcium/Creatinine Ratio in Urine Compared with Proteinuria and Uric Acid in Predicting Preeclampsia: A Study from Kosovo.
Topics: Calcium; Case-Control Studies; Creatinine; Female; Humans; Infant; Kosovo; Pre-Eclampsia; Pregnancy; | 2021 |
Serum catestatin level is increased in women with preeclampsia.
Topics: Adult; Blood Pressure; Case-Control Studies; Chromogranin A; Creatinine; Cross-Sectional Studies; Fe | 2022 |
Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia.
Topics: Adult; Biomarkers; C-Reactive Protein; Calcium; Female; Humans; Infant, Newborn; Interleukin-1beta; | 2021 |
The role of cystatin C, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in the evaluation of kidney function in women with preeclampsia.
Topics: Adult; Biomarkers; Blood Cell Count; Blood Platelets; Case-Control Studies; Creatinine; Cystatin C; | 2021 |
Maternal serum uric acid: a reliable prognostic indicator of foetal outcome among pre-eclamptic patients in a low resource setting.
Topics: Case-Control Studies; Female; Humans; Hyperuricemia; Infant, Newborn; Pre-Eclampsia; Pregnancy; Prog | 2022 |
Comparison of Kidney Function between Gestational Hypertension and Preeclampsia.
Topics: Birth Weight; Creatine; Female; Fetal Development; Gestational Age; Glomerular Filtration Rate; Huma | 2017 |
Maternal serum autotaxin levels in early- and late-onset preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Female; Fetal Blood; Gestational Age; Human | 2017 |
Impact of maternal serum uric acid on perinatal outcome in women with hypertensive disorders of pregnancy: A prospective study.
Topics: Adult; Biomarkers; Female; Humans; Hypertension, Pregnancy-Induced; India; Infant, Newborn; Pre-Ecla | 2017 |
Uric Acid in Pregnancy: New Concepts.
Topics: Apgar Score; Biomarkers; Case-Control Studies; Female; Fetal Development; Fetal Growth Retardation; | 2018 |
Strontium and its role in preeclampsia.
Topics: Adult; Biomarkers; Calcium; Case-Control Studies; Female; Gestational Age; Humans; Hypertension, Pre | 2018 |
Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts.
Topics: Alarmins; C-Reactive Protein; Caspase 1; Cholesterol; Complement C5a; Complement Membrane Attack Com | 2018 |
First versus second trimester mean platelet volume and uric acid for prediction of preeclampsia in women at moderate and low risk.
Topics: Adult; Biomarkers; Female; Humans; Mean Platelet Volume; Parity; Pre-Eclampsia; Pregnancy; Pregnancy | 2018 |
Predictive Value of Maternal Serum Biomarkers for Preeclampsia and Birth Weight: A Case-Control Study in Chinese Pregnant Women.
Topics: Adult; Biomarkers; Birth Weight; Calcium; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; | 2018 |
Serum magnesium level in the first trimester of pregnancy as a predictor of pre-eclampsia - a pilot study.
Topics: Adult; Age Factors; Biomarkers; Chorionic Gonadotropin, beta Subunit, Human; Creatinine; Female; Hum | 2018 |
Secretion of heat shock -60, -70 kD protein, IL-1β and TNFα levels in serum of a term normal pregnancy and patients with pre-eclampsia development.
Topics: Adult; Alanine Transaminase; Amniotic Fluid; Aspartate Aminotransferases; Biomarkers; Chaperonin 60; | 2018 |
Maternal serum uric acid concentration and pregnancy outcomes in women with pre-eclampsia/eclampsia.
Topics: Adult; Apgar Score; Cross-Sectional Studies; Eclampsia; Female; Fetal Growth Retardation; Humans; In | 2019 |
Maternal Serum Uric Acid as a Predictor of Severity of Hypertensive Disorders of Pregnancy: A Prospective Cohort Study.
Topics: Adult; Biomarkers; Blood Pressure; Female; Follow-Up Studies; Gestational Age; Humans; Hypertension, | 2019 |
Serum Cystatin C Levels in Twin Pregnancy versus Singleton Pregnancy.
Topics: Biomarkers; Creatinine; Cystatin C; Female; Glomerular Filtration Rate; Humans; Pre-Eclampsia; Pregn | 2019 |
Evaluation of soluble TNF-like weak inducer of apoptosis (sTWEAK) levels to predict preeclampsia in early weeks of pregnancy.
Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cytokine TWEAK; Female; Gestational Ag | 2019 |
Increased proteinuria and uric acid levels are associated with eclamptic crisis.
Topics: Adult; Biomarkers; Chi-Square Distribution; Creatinine; Disease Progression; Eclampsia; Female; HELL | 2019 |
Maternal serum uric acid and calcium as predictors of hypertensive disorder of pregnancy: A case control study.
Topics: Adult; Biomarkers; Calcium; Case-Control Studies; Female; Humans; Hyperuricemia; Hypocalcemia; Pre-E | 2019 |
Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia.
Topics: Adult; Antirheumatic Agents; Female; Gestational Age; Humans; Hydroxychloroquine; Infant, Newborn; L | 2019 |
Predictive value of serum uric acid levels for adverse perinatal outcomes in preeclampsia.
Topics: Adult; Area Under Curve; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; | 2019 |
Increased serum strontium levels and altered oxidative stress status in early-onset preeclampsia.
Topics: Adult; Age of Onset; Biomarkers; Creatinine; Diagnosis, Differential; Female; Fetal Growth Retardati | 2019 |
Pathogenesis of preeclampsia: Implications of apoptotic markers and oxidative stress.
Topics: Adolescent; Adult; Apoptosis; Caspase 8; Caspase 9; DNA Fragmentation; Female; Humans; Lipid Peroxid | 2013 |
Serum uric acid as a novel marker for uterine atony and post-spinal vasopressor use during cesarean delivery.
Topics: Adult; Anesthesia, Obstetrical; Biomarkers; Blood Loss, Surgical; Cesarean Section; Female; Hematocr | 2013 |
Contribution of dysfunction of maternal hemodynamics to renal impairment in preeclampsia.
Topics: Adult; Area Under Curve; Blood Pressure; Blood Urea Nitrogen; Cardiography, Impedance; Creatinine; F | 2013 |
[Value of serum cystatin C level in assessing renal damage in preeclamptic patients].
Topics: beta 2-Microglobulin; Case-Control Studies; Creatinine; Cystatin C; Female; Humans; Kidney; Pre-Ecla | 2013 |
Analysis of purine metabolites in maternal serum for evaluating the risk of gestosis.
Topics: Adult; Biomarkers; Chromatography, Reverse-Phase; Female; Gestational Age; Humans; Hypoxanthine; Inf | 2013 |
The use of pulse wave velocity in predicting pre-eclampsia in high-risk women.
Topics: Adolescent; Adult; Biomarkers; Calcium; Female; Humans; Pre-Eclampsia; Predictive Value of Tests; Pr | 2014 |
Association between uric acid and severity of pre-eclampsia.
Topics: Adult; Blood Pressure; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Uric Acid | 2014 |
Maternal venous hemodynamics in gestational hypertension and preeclampsia.
Topics: Adult; Blood Pressure; Cardiography, Impedance; Cross-Sectional Studies; Echocardiography, Doppler; | 2014 |
Second trimester amniotic fluid retinol in patients developing preeclampsia.
Topics: Adult; Amniotic Fluid; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Femal | 2015 |
Hydroxychloroquine and pregnancy on lupus flares in Korean patients with systemic lupus erythematosus.
Topics: Adult; Antirheumatic Agents; Apgar Score; Female; Fetal Growth Retardation; Follow-Up Studies; Human | 2015 |
Uric Acid as a predictor of adverse maternal and perinatal outcomes in women hospitalized with preeclampsia.
Topics: Adult; Cohort Studies; Female; Humans; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnanc | 2014 |
[Serum uric acid levels and risk of developing preeclampsia].
Topics: Adult; Birth Weight; Creatinine; Early Diagnosis; Female; Humans; Hypertension; Infant, Low Birth We | 2014 |
Uric Acid Determination in Gestational Hypertension: Is it as Effective a Delineator of Risk as Proteinuria in High-Risk Women?
Topics: Adolescent; Adult; Biomarkers; Clinical Trials as Topic; Female; Gestational Age; Humans; Hypertensi | 2015 |
Persistence of cardiovascular risk factors in women with previous preeclampsia: a long-term follow-up study.
Topics: Adult; Albuminuria; Cardiovascular Diseases; Carotid Intima-Media Thickness; Case-Control Studies; F | 2015 |
Serum uric acid level in normal pregnant and preeclamptic ladies: a comparative study.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid; Young | 2014 |
Serum uric acid may not be involved in the development of preeclampsia.
Topics: Adolescent; Adult; Biomarkers; Blood Pressure; Female; Follow-Up Studies; Humans; Middle Aged; Pre-E | 2016 |
Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Apoptosis Regulatory Proteins; Carrier Prot | 2015 |
Clinical presentation, assessment and management of pre-eclampsia.
Topics: Disease Management; Early Diagnosis; Education, Nursing, Continuing; Female; Humans; Pre-Eclampsia; | 2015 |
Independent Determinants of Maternal and Fetal Outcomes in a Sample of Pregnant Outpatients With Normal Blood Pressure, Chronic Hypertension, Gestational Hypertension, and Preeclampsia.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Mass Index; Female; Humans; Hypertension, Pregn | 2015 |
The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia.
Topics: Adult; Allantoin; Arterial Pressure; Case-Control Studies; Female; Humans; Hypertension; Nitrites; P | 2016 |
Maternal serum uric acid concentration is associated with the expression of tumour necrosis factor-α and intercellular adhesion molecule-1 in patients with preeclampsia.
Topics: Adult; Biomarkers; Blood Pressure; Case-Control Studies; Female; Humans; Inflammation Mediators; Int | 2016 |
Ceruloplasmin and antioxidative enzymes in pre-eclampsia.
Topics: Adult; Analysis of Variance; Biomarkers; Case-Control Studies; Ceruloplasmin; Chi-Square Distributio | 2016 |
Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study.
Topics: Adolescent; Adult; Apoptosis; Biomarkers; Creatine; Cytokine TWEAK; Down-Regulation; Female; Humans; | 2016 |
Serum nitrate and NOx levels in preeclampsia are higher than in normal pregnancy.
Topics: Adolescent; Adult; Blood Pressure; Female; Gestational Age; Humans; Nitrates; Nitric Oxide; Nitrites | 2016 |
Increased expression of high mobility group box 1 (HMGB1) in the cytoplasm of placental syncytiotrophoblast from preeclamptic placentae.
Topics: Adolescent; Adult; Cytoplasm; Female; HMGB1 Protein; Humans; Placenta; Pre-Eclampsia; Pregnancy; Tro | 2016 |
Elevated circulatingadenosine deaminase activity in women with preeclampsia: association with pro-inflammatory cytokine production and uric acid levels.
Topics: Adenosine Deaminase; Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Humans; Interleuki | 2016 |
Second trimester amniotic fluid uric acid, potassium, and cysteine to methionine ratio levels as possible signs of early preeclampsia: A case report.
Topics: Adult; Amniocentesis; Amniotic Fluid; Biomarkers; Cysteine; Female; Fetal Growth Retardation; Humans | 2016 |
Association of biochemical markers with the severity of pre-eclampsia.
Topics: Adult; Alanine Transaminase; Biomarkers; Blood Urea Nitrogen; C-Reactive Protein; Egypt; Female; Hum | 2017 |
Screening for pre-eclampsia by oxidative stress markers and uteroplacental blood flow.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Fetal Growth Retardation; Follow-Up Studies; Gestat | 2008 |
Retinopathy in preeclampsia: association with birth weight and uric acid level.
Topics: Adolescent; Adult; Birth Weight; Blood Pressure; Female; Fetal Growth Retardation; Humans; Infant, N | 2008 |
Serum uric acid levels correlate with plasma hydrogen peroxide and protein carbonyl levels in preeclampsia.
Topics: Adult; Biomarkers; Colorimetry; Female; Humans; Hydrogen Peroxide; Oxidative Stress; Pre-Eclampsia; | 2008 |
Serum calcium, magnesium and uric acid in preeclampsia and normal pregnancy.
Topics: Adult; Analysis of Variance; Calcium; Cross-Sectional Studies; Female; Humans; Hyperuricemia; Hypoca | 2008 |
Uric acid inhibits placental system A amino acid uptake.
Topics: Acetophenones; Adult; Amino Acid Transport System A; Amino Acids; Antioxidants; Cell Survival; Chori | 2009 |
Reactions of peroxynitrite with uric acid: formation of reactive intermediates, alkylated products and triuret, and in vivo production of triuret under conditions of oxidative stress.
Topics: Antioxidants; Female; Humans; Hyperuricemia; Oxidants; Oxidative Stress; Peroxynitrous Acid; Pre-Ecl | 2009 |
Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayers.
Topics: Adult; Antioxidants; Apoptosis; Cell Line; Cell Movement; Cells, Cultured; Coculture Techniques; End | 2009 |
Optimal laboratory panel for predicting preeclampsia.
Topics: Aspartate Aminotransferases; Biomarkers; Creatinine; Female; Hematocrit; Humans; Leukocyte Count; Mu | 2010 |
Insulin resistance and C-reactive protein in preeclampsia.
Topics: Adult; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Databases, Factual; Femal | 2009 |
Leptin levels and antihypertensive treatment in preeclampsia.
Topics: Adult; Antihypertensive Agents; Case-Control Studies; Female; Humans; Leptin; Platelet Count; Pre-Ec | 2010 |
Factors associated with persistent hypertension after puerperium among women with pre-eclampsia/eclampsia in Mulago hospital, Uganda.
Topics: Adolescent; Adult; Case-Control Studies; Chronic Disease; Creatinine; Eclampsia; Female; Humans; Hyp | 2010 |
Prevalence of cesarean delivery in preeclamptic patients with elevated uric acid.
Topics: Cesarean Section; Female; Gestational Age; Humans; Intensive Care Units, Neonatal; Pre-Eclampsia; Pr | 2010 |
High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia.
Topics: Adult; Biomarkers; Diabetes, Gestational; Female; Humans; Multivariate Analysis; Pre-Eclampsia; Preg | 2012 |
A survey of the twenty-four-hour uric acid and urea clearances in eclampsia and severe preeclampsia.
Topics: Eclampsia; Female; Humans; Pre-Eclampsia; Pregnancy; Urea; Uric Acid | 1946 |
Elevated serum-soluble Fas in preeclampsia: correlation with clinical, laboratory, and Doppler parameters.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Cross-Sectional Studies; fas Receptor; Female; Humans; P | 2011 |
First trimester uric acid and adverse pregnancy outcomes.
Topics: Adult; Female; Humans; Hypertension, Pregnancy-Induced; Hyperuricemia; Infant, Newborn; Infant, Smal | 2011 |
Uric acid induces trophoblast IL-1β production via the inflammasome: implications for the pathogenesis of preeclampsia.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins | 2011 |
8-Hydroxy-2-deoxyguanosine staining in placenta is associated with maternal serum uric acid levels and gestational age at diagnosis in pre-eclampsia.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Age Factors; Biomarkers; Case-Control Studies; Deoxyguanosine; E | 2011 |
Increased reactive oxygen species and tumor necrosis factor-alpha production by monocytes are associated with elevated levels of uric acid in pre-eclamptic women.
Topics: Adolescent; Adult; Catalase; Female; Humans; Hydrogen Peroxide; Monocytes; Pre-Eclampsia; Pregnancy; | 2011 |
Cystatin C in pre-eclampsia.
Topics: Adult; Biomarkers; Creatinine; Cystatin C; Female; Humans; Pre-Eclampsia; Pregnancy; ROC Curve; Uric | 2012 |
Prognostic significance of serum uric acid in women with gestational hypertension.
Topics: Adult; Biomarkers; Blood Pressure; Female; Follow-Up Studies; Gestational Age; Humans; Hypertension, | 2011 |
Uric acid: a clinically useful marker to distinguish preeclampsia from gestational hypertension.
Topics: Female; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Infant, Low Birth Weight; Pre-Ecla | 2011 |
[Association between plasma levels of soluble leukocyte differentiation antigens CD₄₀/CD₄₀ ligand and kidney damage in preeclamptic patients].
Topics: Adult; Biomarkers; Blood Pressure; C-Reactive Protein; Case-Control Studies; CD40 Antigens; CD40 Lig | 2011 |
Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy.
Topics: Adult; Carcinoma; Cesarean Section; Female; Humans; Hypercalcemia; Infant, Newborn; Parathyroid Neop | 2012 |
Admission uric acid levels and length of expectant management in preterm preeclampsia.
Topics: Adolescent; Adult; Delivery, Obstetric; Female; Gestational Age; Humans; Patient Admission; Pre-Ecla | 2012 |
Plasma uric acid remains a marker of poor outcome in hypertensive pregnancy: a retrospective cohort study.
Topics: Adult; Algorithms; Antioxidants; Australia; Biomarkers; Cohort Studies; Female; Hematocrit; Hemoglob | 2012 |
Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies.
Topics: Adult; Biomarkers; Blood Pressure; Cohort Studies; Disease Progression; Female; Gestational Age; Hum | 2012 |
Calciuria and preeclampsia: a case-control study.
Topics: Adult; Calcium; Case-Control Studies; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; ROC Cu | 2012 |
Correlation of biochemical parameters and neonatal outcome in patients with gestational hypertension.
Topics: Apgar Score; Blood Glucose; Case-Control Studies; Creatinine; Female; HELLP Syndrome; Humans; Hypert | 2013 |
Inflammatory disturbances in preeclampsia: relationship between maternal and umbilical cord blood.
Topics: Adult; alpha 1-Antitrypsin; Antioxidants; Biomarkers; C-Reactive Protein; Case-Control Studies; Enzy | 2012 |
Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes.
Topics: Adult; Diabetes, Gestational; Female; Humans; Lipids; Longitudinal Studies; Pre-Eclampsia; Pregnancy | 2012 |
Increased oxidant generation in the metabolism of hypoxanthine to uric acid and endothelial dysfunction in early-onset and late-onset preeclamptic women.
Topics: Adult; Age of Onset; Case-Control Studies; Endothelium, Vascular; Female; Gestational Age; Humans; H | 2012 |
[Diagnostic value of radom spot albuminuria to creatinine ratio in women with preeclampsia].
Topics: Adult; Albumins; Albuminuria; Biomarkers; Creatinine; Female; Humans; Pre-Eclampsia; Predictive Valu | 2012 |
[Correlation of lipocalin-2 and its receptor expressions with preeclampsia].
Topics: Acute-Phase Proteins; Adult; Blood Pressure; Case-Control Studies; Enzyme-Linked Immunosorbent Assay | 2012 |
Electrochemical-surface enhanced Raman spectroscopy (E-SERS) of uric acid: a potential rapid diagnostic method for early preeclampsia detection.
Topics: Electrochemical Techniques; Female; Humans; Metal Nanoparticles; Pre-Eclampsia; Pregnancy; Silver; S | 2013 |
Predictors of preterm birth in patients with mild systemic lupus erythematosus.
Topics: Adult; Biomarkers; Cohort Studies; Comorbidity; Creatine; Estradiol; Female; Ferritins; Gestational | 2013 |
The role of serum uric acid as a prognostic indicator of the severity of maternal and fetal complications in hypertensive pregnancies.
Topics: Biomarkers; Case-Control Studies; Female; Fetal Growth Retardation; HELLP Syndrome; Humans; Infant, | 2002 |
Individual longitudinal patterns in biochemical and hematological markers for the early prediction of pre-eclampsia.
Topics: Adult; Biomarkers; Blood Proteins; Creatinine; Female; Gestational Age; Hematocrit; Humans; Longitud | 2002 |
Plasma 5'-nucleotidase activities and uric acid levels in women with pre-eclampsia.
Topics: 5'-Nucleotidase; Adult; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Severity of | 2002 |
The significance of serum uric acid, creatinine and urinary microprotein levels in predicting pre-eclampsia.
Topics: Biomarkers; Blood Pressure; Creatinine; Cross-Sectional Studies; Female; Humans; Pre-Eclampsia; Pred | 2003 |
Evidence of impaired microvascular function in pre-eclampsia: a non-invasive study.
Topics: Adult; Case-Control Studies; E-Selectin; Endothelium, Vascular; Female; Hematocrit; Humans; Intercel | 2003 |
Microvascular permeability is related to circulating levels of tumour necrosis factor-alpha in pre-eclampsia.
Topics: Adult; Analysis of Variance; Capillary Permeability; Endothelial Growth Factors; Female; Humans; Int | 2003 |
Evaluation of a rat model of preeclampsia for HELLP syndrome characteristics.
Topics: Animals; Aorta; Arteries; Blood Cell Count; Blood Pressure; Constriction; Creatinine; Disease Models | 2003 |
Pre-eclampsia: prediction.
Topics: Blood Pressure; Calcium; Creatinine; Epoprostenol; Female; Humans; Kallikreins; Pre-Eclampsia; Pregn | 2003 |
Severe pre-eclampsia and maternal thyroid function.
Topics: Adult; Albuminuria; Blood Pressure; Case-Control Studies; Female; Gestational Age; Humans; Pre-Eclam | 2003 |
Neutrophil activation and C-reactive protein concentration in preeclampsia.
Topics: Adult; Biomarkers; C-Reactive Protein; Case-Control Studies; Cohort Studies; Female; Granulocyte-Mac | 2003 |
Observations on the renal tubular reabsorption of uric acid. I. Normal pregnancy and abnormal pregnancy with and without pre-eclampsia.
Topics: Female; Humans; Kidney; Pre-Eclampsia; Pregnancy; Uric Acid | 1953 |
The value of blood uric acid levels in toxaemia of pregnancy.
Topics: Bacterial Infections; Blood; Female; Humans; Pre-Eclampsia; Pregnancy; Sepsis; Toxemia; Uric Acid | 1956 |
Uric acid and endogenous creatinine clearance studies in normal pregnancy and toxemias of pregnancy.
Topics: Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Toxemia; Uric Acid | 1956 |
The metabolism of urate in pre-eclampsia.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1956 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
The effect of benemid on uric acid excretion in normal pregnancy and in pre-eclampsia.
Topics: Biological Transport; Body Fluids; Female; Humans; Pre-Eclampsia; Pregnancy; Probenecid; Uric Acid | 1957 |
Uric acid and endogenous creatinine clearances after normal and toxemic pregnancy.
Topics: Body Fluids; Creatinine; Female; Humans; Kidney Function Tests; Postpartum Period; Pre-Eclampsia; Pr | 1957 |
Uric acid and endogenous creatinine clearances after normal and toxemic pregnancy.
Topics: Body Fluids; Creatinine; Female; Humans; Kidney Function Tests; Postpartum Period; Pre-Eclampsia; Pr | 1957 |
Uric acid and endogenous creatinine clearances after normal and toxemic pregnancy.
Topics: Body Fluids; Creatinine; Female; Humans; Kidney Function Tests; Postpartum Period; Pre-Eclampsia; Pr | 1957 |
Uric acid and endogenous creatinine clearances after normal and toxemic pregnancy.
Topics: Body Fluids; Creatinine; Female; Humans; Kidney Function Tests; Postpartum Period; Pre-Eclampsia; Pr | 1957 |
Nitrogenous retention in patients with toxemia of pregnancy; an unusual complication of salt restriction.
Topics: Diet; Female; Humans; Pre-Eclampsia; Pregnancy; Urea; Uric Acid | 1957 |
Plasma uric acid levels, uric acid excretion, and response to probenecid in toxemia of pregnancy.
Topics: Biological Transport; Body Fluids; Female; Humans; Plasma; Pre-Eclampsia; Pregnancy; Probenecid; Uri | 1958 |
Further studies on the metabolism of N 15-labeled uric acid in normal and toxemic pregnant women.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Sepsis; Uric Acid | 1958 |
The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy.
Topics: Body Fluids; Female; Humans; Lactates; Lactic Acid; Pre-Eclampsia; Pregnancy; Uric Acid | 1960 |
EFFECTS OF DIET AND DIURETIC AGENTS IN PREGNANCY TOXEMIAS.
Topics: Blood; Body Fluids; Chlorides; Creatine; Creatinine; Diet Therapy; Diet, Sodium-Restricted; Dietary | 1963 |
RENAL ARTERIOLAR DISEASE IN YOUNG PRIMIPARAS.
Topics: Adolescent; Arteries; Black People; Blood Chemical Analysis; Body Weight; Eclampsia; Female; Humans; | 1964 |
URIC ACID CONTENTS OF MATERNAL AND FOETAL BLOOD IN NORMAL AND TOXAEMIC PREGNANCIES.
Topics: Blood; Female; Fetal Blood; Fetus; Humans; Maternal-Fetal Exchange; Nucleic Acids; Pre-Eclampsia; Pr | 1964 |
USE OF BENDROFLUMETHIAZIDE WITH POTASSIUM SUPPLEMENT IN TOXEMIA OF PREGNANCY.
Topics: Bendroflumethiazide; Blood; Blood Pressure; Drug Therapy; Eclampsia; Edema; Female; Fetal Death; Hum | 1965 |
URIC ACID IN HUMAN PLASMA. II. INVESTIGATIONS ON THE POSSIBLE PRESENCE OF URIC ACID COVALENTLY LINKED TO PLASMA MACROMOLECULES.
Topics: Arthritis; Arthritis, Rheumatoid; Blood; Chromatography; Chromatography, Gel; Female; Gout; Humans; | 1965 |
SERUM URIC ACID IN TOXAEMIA OF PREGNANCY WITH SPECIAL REFERENCE TO THE PROGNOSIS OF THE FOETUS.
Topics: Birth Weight; Blood; Delivery, Obstetric; Female; Fetal Death; Fetus; Humans; Hyperemesis Gravidarum | 1964 |
THE PROGNOSIS OF THE FOETUS IN RELATION TO THE SERUM URIC ACID IN TOXAEMIA OF PREGNANCY.
Topics: Bacterial Infections; Blood; Female; Fetus; Humans; Pre-Eclampsia; Pregnancy; Prognosis; Sepsis; Uri | 1965 |
[Index of uric acid in blood and uremia in pregnancy toxemia].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Toxemia; Uremia; Uric Acid | 1959 |
The hyperuricemic effect of chlorothiazide (diuril) in pregnant women: preliminary report.
Topics: Chlorothiazide; Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1960 |
Cerebrospinal fluid nitric oxide level changes in preeclampsia.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Birth Weight; Blood Pressure; Female; Gest | 2003 |
Serum albumin, creatinine, uric acid and hypertensive disorders of pregnancy.
Topics: Adult; Creatinine; Female; Gravidity; Humans; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; S | 2003 |
[Risk factors for eclampsia: a case-control study].
Topics: Adult; Analysis of Variance; Aspartate Aminotransferases; Case-Control Studies; Creatinine; Eclampsi | 2003 |
Reduced antioxidant capacity in second-trimester pregnancies with pathological uterine perfusion.
Topics: Adult; Antioxidants; Female; Fetal Growth Retardation; Humans; Oxidative Stress; Placental Circulati | 2004 |
Nitric oxide production is not altered in preeclampsia.
Topics: Adult; Blood Pressure; Case-Control Studies; Chromatography, High Pressure Liquid; Creatinine; Femal | 2004 |
Is there any link between insulin resistance and inflammation in established preeclampsia?
Topics: Biomarkers; Case-Control Studies; Female; Humans; Inflammation; Inflammation Mediators; Insulin Resi | 2004 |
A prediction model for superimposed preeclampsia in women with chronic hypertension during pregnancy.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Models, Theoretical; Pre-Eclampsia; Predictive | 2004 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hype | 2004 |
Measurement of the total antioxidant response in preeclampsia with a novel automated method.
Topics: Adult; Antioxidants; Ascorbic Acid; Autoanalysis; Bilirubin; Colorimetry; Female; Humans; Oxidative | 2005 |
Uric acid and preeclampsia.
Topics: Animals; Arteries; Blood Pressure; Endothelium, Vascular; Female; Humans; Hyperuricemia; Pre-Eclamps | 2005 |
Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia.
Topics: Adult; Biomarkers; Female; Humans; Hypertension; Membrane Proteins; Pre-Eclampsia; Pregnancy; Pregna | 2005 |
Elevated serum uric acid levels in gestational hypertension are correlated with insulin resistance.
Topics: Adult; Body Mass Index; Creatinine; Female; Homeostasis; Humans; Hypertension, Pregnancy-Induced; In | 2005 |
Elevated plasma homocysteine concentrations in severe preeclampsia and eclampsia.
Topics: Adult; Body Mass Index; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Re | 2005 |
Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome. A study in 453 consecutive pregnancies.
Topics: Abscess; Adult; Ascites; Cesarean Section; Creatinine; Disseminated Intravascular Coagulation; Femal | 2006 |
Calciuria and preeclampsia: a case-control study.
Topics: Adolescent; Adult; Calcium; Creatinine; Epidemiologic Methods; Female; Humans; Pre-Eclampsia; Pregna | 2006 |
The correlation between renal function and systolic or diastolic blood pressure in severe preeclamptic women.
Topics: Adult; Blood Urea Nitrogen; Calcium; Chi-Square Distribution; Creatinine; Diastole; Female; Humans; | 2005 |
The predictive value of serum uric acid, roll-over test, and body mass index in pre-eclampsia.
Topics: Blood Pressure; Body Mass Index; Chi-Square Distribution; Female; Humans; Movement; Pre-Eclampsia; P | 2006 |
Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery.
Topics: Adult; Case-Control Studies; Creatinine; Delivery, Obstetric; Female; Glomerular Filtration Rate; Hu | 2006 |
Increase in serum concentrations of inhibin in early onset pre-eclampsia with intrauterine growth restriction.
Topics: Adult; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Inhibins; Placental Circulati | 2006 |
Effects of postpartum uterine curettage on maternal well-being in severe preeclamptic patients.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Pressure; Delivery, Obstetric; Dilat | 2006 |
Are d-ROMs and FRAP tests suitable assays for detecting the oxidative status?
Topics: Adult; Antioxidants; Blood Chemical Analysis; Female; Humans; Oxidative Stress; Pre-Eclampsia; Pregn | 2006 |
Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus.
Topics: Adult; Creatinine; Diabetes, Gestational; Female; Glomerular Filtration Rate; Glucose Tolerance Test | 2006 |
Plasma uric acid levels do not correlate to plasma-evoked changes in endothelial function in women with preeclampsia.
Topics: Arteries; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Myome | 2008 |
Tumor necrosis factor-alpha in gestation and puerperium of women with gestational hypertension and pre-eclampsia.
Topics: Adolescent; Adult; Cells, Cultured; Female; Humans; Hypertension, Pregnancy-Induced; Lipopolysacchar | 2007 |
[Changes of serum cardiotrophin I and cystatin C in preeclampsia and clinical significance thereof].
Topics: Adolescent; Adult; Analysis of Variance; Case-Control Studies; Creatine; Creatine Kinase; Cystatin C | 2006 |
Detection and identification of novel metabolomic biomarkers in preeclampsia.
Topics: Alanine; Biomarkers; Cohort Studies; Female; Glutamic Acid; Humans; Infant, Newborn; Ketoglutaric Ac | 2008 |
Relationships between toxemia of pregnancy and essential hypertension in a total community.
Topics: Adolescent; Adult; Blood Glucose; Child; Child, Preschool; Cholesterol; Eclampsia; Female; Glucose T | 1967 |
[Data for the study of the gouty kidney].
Topics: Adolescent; Adult; Female; Glomerulonephritis; Gout; Humans; Kidney Calculi; Kidney Diseases, Cystic | 1967 |
Serum uric acid levels as an index of fetal prognosis in pregnancies complicated by pre-existing hypertension and pre-eclampsia of pregnancy.
Topics: Birth Weight; Estrogens; Female; Fetal Distress; Fetal Growth Retardation; Humans; Hypertension; Inf | 1982 |
Clinical manifestations and diagnosis of pregnancy-induced hypertension.
Topics: Angiotensin II; Antigens; Antithrombin III; Bed Rest; Diastole; Endothelium; Factor VIII; Female; Hu | 1984 |
[Pharmacokinetics and electrolyte balance following administration of furosemide in pregnant women with E gestosis].
Topics: Calcium; Chlorides; Creatinine; Female; Furosemide; Humans; Kinetics; Models, Biological; Potassium; | 1984 |
[Significance of serum uric acid determination for the early detection of complications of hypertensive pregnancy in primigravidae].
Topics: Adolescent; Adult; Diagnosis, Differential; Female; Gestational Age; Humans; Pre-Eclampsia; Pregnanc | 1984 |
[Uricemia as a diagnostic and prognostic criterion in the EPH syndrome].
Topics: Birth Weight; Female; Fetal Death; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy Trim | 1984 |
[Serum uric acid levels in physiological pregnancy and in pregnancy complicated by EPH gestosis].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Uric Acid | 1984 |
Serum urate as a predictor of fetal outcome in severe pre-eclampsia.
Topics: Adolescent; Adult; Erythrocyte Volume; Female; Fetal Death; Fetal Distress; Fetal Growth Retardation | 1984 |
Platelet production time, uricemia, and some hemostasis tests in pre-eclampsia.
Topics: Adult; Antigens; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Factor VIII; Female; H | 1980 |
[Serum uric acid as a prognostic parameter in prenatal monitoring of gestoses].
Topics: Female; Fetal Death; Fetal Monitoring; Gestational Age; Humans; Hypertension; Obstetric Labor Compli | 1983 |
[The value of a single determination of serum uric acid concentration in the early diagnosis of hypertensive disorders in pregnancy (author's transl)].
Topics: Adolescent; Adult; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, | 1982 |
Serum uric acid as a marker of pregnancy-induced hypertension.
Topics: Adult; Female; Humans; Hypertension; Longitudinal Studies; Pre-Eclampsia; Pregnancy; Pregnancy Compl | 1982 |
Results of a prospective study of toxemia of pregnancy.
Topics: Adolescent; Adult; Blood Pressure; Creatinine; Female; Follow-Up Studies; Glomerular Filtration Rate | 1981 |
Estimation of decision criteria for the uric acid concentration for the early diagnosis of gestosis.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Time Factors; Uric Acid | 1981 |
[Significance of uric acid concentration in the serum for the early recognition of the risk of EPH gestosis].
Topics: Eclampsia; Female; Humans; Hypertension; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Uric Aci | 1981 |
The likelihood quotient line, a tool for the assessment of diagnostic validity of clinical chemical tests.
Topics: Clinical Laboratory Techniques; Female; Humans; Pre-Eclampsia; Pregnancy; Quality Control; Reference | 1981 |
Renal lesions in the hypertensive syndromes of pregnancy: immunomorphological and ultrastructural studies in 114 cases.
Topics: Adult; Female; Humans; Hypertension; Kidney; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Card | 1980 |
Disseminated intravascular coagulation in toxaemia of pregnancy. Correction of the decreased platelet counts and raised levels of serum uric acid and fibrin(ogen) degradation products by aspirin.
Topics: Adult; Aspirin; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Produc | 1980 |
Maternal plasma level of thrombomodulin is increased in mild preeclampsia.
Topics: Adult; Blood Pressure; Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Thrombomodulin; Uric Ac | 1995 |
Lipid peroxidation in normal pregnancy and preeclampsia.
Topics: Blood Pressure; Cholesterol; Female; Humans; Lipid Peroxidation; Lipid Peroxides; Platelet Count; Pr | 1994 |
Maternal serum uric acid levels in twin gestations.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Female; Gestational Age; Humans; Pre-Eclampsia; | 1995 |
The total peroxyl radical-trapping ability of plasma and cerebrospinal fluid in normal and preeclamptic parturients.
Topics: Antioxidants; Ascorbic Acid; Female; Humans; Labor, Obstetric; Peroxides; Pre-Eclampsia; Pregnancy; | 1994 |
The duration of hypertension in the puerperium of preeclamptic women: relationship with renal impairment and week of delivery.
Topics: Adult; Blood Pressure; Female; Gestational Age; Humans; Hypertension; Kidney Diseases; Parity; Postp | 1994 |
Management of severe, early pre-eclampsia: is conservative management justified?
Topics: Birth Weight; Blood Pressure; Dexamethasone; Female; Humans; Hypertension; Infant Mortality; Infant, | 1993 |
Calcium metabolism, plasma parathyroid hormone, and calcitriol in transient hypertension of pregnancy.
Topics: Adult; Blood Pressure; Calcitriol; Calcium; Carrier Proteins; Dicarboxylic Acid Transporters; Female | 1993 |
Elevated circulating thrombomodulin in severe preeclampsia.
Topics: Adult; Blood Pressure; Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Proteinuria; Receptors, | 1993 |
Placental bed lesions and infant birth weight in hypertensive pregnant women.
Topics: Adult; Arteriosclerosis; Birth Weight; Creatinine; Female; Gestational Age; Humans; Hypertension; In | 1995 |
Pre-eclampsia: excessive activation of a G protein-associated receptor?
Topics: Arachidonic Acids; Calcium; Endothelium, Vascular; Fatty Liver; Female; GTP-Binding Proteins; Humans | 1995 |
Poor predictive value of platelet count, mean platelet volume and serum urate in hypertension in pregnancy.
Topics: Female; Humans; Hypertension; Platelet Count; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; P | 1996 |
Hyperuricemia and pregnancy induced hypertension--reappraisal.
Topics: Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Uri | 1996 |
Neutrophil CD11B expression and neutrophil activation in pre-eclampsia.
Topics: Adult; CD18 Antigens; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Macrophage-1 | 1997 |
Are high uric acid levels in patients with early pre-eclampsia an indication for delivery?
Topics: Adult; Antihypertensive Agents; Creatinine; Female; Fetal Growth Retardation; Gestational Age; Human | 1997 |
Biochemical prediction of pre-eclampsia.
Topics: Atrial Natriuretic Factor; Blood Coagulation Factors; Calcium; Endothelium, Vascular; Female; Humans | 1997 |
A discriminant function for preeclampsia: case-control study of minor hemoglobins, red cell enzymes, and clinical laboratory values.
Topics: Adult; Biomarkers; Case-Control Studies; Chromatography, Ion Exchange; Discriminant Analysis; Erythr | 1997 |
Elevation of the serum uric acid level preceding the clinical manifestation of preeclampsia in twin pregnancies.
Topics: Cohort Studies; Female; Humans; Japan; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Pregnan | 1997 |
Fetal renal hyperechogenicity in pathological pregnancies.
Topics: Female; Fetal Growth Retardation; Gestational Age; Humans; Infant, Newborn; Kidney; Pre-Eclampsia; P | 1997 |
Plasma fibronectin: predictive factor in gestational hypertension?
Topics: Adult; Female; Fibronectins; Humans; Hypertension; Pre-Eclampsia; Predictive Value of Tests; Pregnan | 1997 |
Reversed circadian blood pressure rhythm preserves fetal growth in preeclamptic pregnancy.
Topics: Adolescent; Adult; Alanine Transaminase; Albuminuria; Aspartate Aminotransferases; Blood Pressure; B | 1997 |
Lone hyperuricemia during pregnancy: maternal and fetal outcomes.
Topics: Adult; Birth Weight; Female; Gestational Age; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complicati | 1998 |
Maternal serum uric acid levels in preeclamptic women with multiple gestations.
Topics: Adult; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy, Multiple; ROC Curve; Uric Acid | 1997 |
Erythrocyte glutathione balance and membrane stability during preeclampsia.
Topics: Erythrocyte Membrane; Erythrocytes; Female; Glutathione; Humans; Intracellular Fluid; Magnetic Reson | 1998 |
The clinical utility of serum uric acid measurements in hypertensive diseases of pregnancy.
Topics: Case-Control Studies; Chronic Disease; Diagnosis, Differential; Female; Humans; Hypertension; Pre-Ec | 1998 |
Maternal serum uric acid levels in preeclamptic twin pregnancies.
Topics: Female; Gestational Age; Humans; Pre-Eclampsia; Pregnancy; Pregnancy, Multiple; ROC Curve; Twins; Ur | 1998 |
Calciuria and preeclampsia.
Topics: Calcium; Chronic Disease; Cross-Sectional Studies; Female; Humans; Hypertension; Pre-Eclampsia; Preg | 1998 |
Urinary N-acetyl-beta-glucosaminidase in the prediction of preeclampsia.
Topics: Acetylglucosaminidase; Adult; Albuminuria; Clinical Enzyme Tests; Creatinine; Female; Humans; Hypert | 1998 |
Risk factors for abruptio placentae and eclampsia: analysis of 445 consecutively managed women with severe preeclampsia and eclampsia.
Topics: Abruptio Placentae; Adolescent; Adult; Blood Pressure; Eclampsia; Female; Headache; Humans; Logistic | 1999 |
The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification.
Topics: Aspartate Aminotransferases; Birth Weight; Cesarean Section; Eclampsia; Female; Fetal Death; Headach | 1999 |
Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Creatinine; Female; HELLP Syndrome; Humans; L-Lac | 1999 |
Evidence of a state of increased insulin resistance in preeclampsia.
Topics: Adult; C-Peptide; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Insulin Resist | 1999 |
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Pressure; Body Mass Index; Causality; Creatinine; Endothe | 1999 |
Placental pathologies are not associated with hyperuricemia in preeclamptic pregnancies.
Topics: Data Interpretation, Statistical; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Retrospective | 1999 |
Is carbohydrate metabolism altered among women who have undergone a preeclamptic pregnancy?
Topics: Adult; Androgens; Blood Glucose; Blood Pressure; Body Mass Index; Carbohydrate Metabolism; Fasting; | 1999 |
[Excretion of uric aid, sodium, and potassium in preeclampsia patients and its behavior in acute hyperglycemia-hyperinsulinemia].
Topics: Acute Disease; Adult; Female; Humans; Hyperglycemia; Hyperinsulinism; Potassium; Pre-Eclampsia; Preg | 1999 |
Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes.
Topics: Adult; Birth Weight; Creatinine; Female; Gestational Age; Glutathione; Humans; Infant, Newborn; Pre- | 2000 |
Laboratory testing for preeclampsia: result trends and screening recommendations.
Topics: Adolescent; Adult; Blood Urea Nitrogen; Creatinine; Female; Humans; Liver Function Tests; Mass Scree | 2000 |
The clinical utility of serum uric acid measurements in pre-eclampsia and transient hypertension in pregnancy.
Topics: Biomarkers; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Uric Ac | 2000 |
Longitudinal analysis of maternal plasma leptin concentrations during normal pregnancy and pre-eclampsia.
Topics: Adult; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Gestational Age; Humans; Le | 2000 |
Estimation of cord blood erythropoietin in pre-eclampsia and eclampsia.
Topics: Adult; Albuminuria; Apgar Score; Biomarkers; Birth Weight; Blood Pressure; Case-Control Studies; Ecl | 2000 |
Tissue kallikrein activity in pregnancy.
Topics: Adult; Analysis of Variance; Black People; Case-Control Studies; Creatinine; Female; Humans; Hyperte | 2000 |
[Twin pregnancy and preeclampsia].
Topics: Adult; Biomarkers; Comorbidity; Edema; Female; Gravidity; Humans; Hypertension; Incidence; Parity; P | 2000 |
Relation between serum uric acid and plasma adenosine levels in women with preeclampsia.
Topics: Adenosine; Adult; Arteries; Female; Gestational Age; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 2001 |
Hyperuricemia, oxidative stress in preeclampsia.
Topics: Female; Humans; Malondialdehyde; Oxidative Stress; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Th | 2001 |
Levels of dimethylarginines and cytokines in mild and severe preeclampsia.
Topics: Arginine; Blood Pressure; Cytokines; Female; Gestational Age; Humans; Nitric Oxide Synthase; Pre-Ecl | 2001 |
Hypertension and its relation to renal function 10 years after pregnancy complicated by pre-eclampsia and pregnancy induced hypertension.
Topics: Adult; Blood Urea Nitrogen; Body Weight; Calcium; Case-Control Studies; Chronic Disease; Creatinine; | 2000 |
Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes.
Topics: Albumins; Allopurinol; Animals; Bilirubin; Blood Pressure; Fasting; Female; Heme; Hypertension; Hypo | 2001 |
Serum cystatin C is a better marker for preeclampsia than serum creatinine or serum urate.
Topics: Case-Control Studies; Creatinine; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Humans; | 2001 |
Ambulatory blood pressure as predictor of preeclampsia in diabetic pregnancies with respect to urinary albumin excretion rate and glycemic regulation.
Topics: Adolescent; Adult; Albuminuria; Birth Weight; Blood Glucose; Blood Pressure; Blood Pressure Monitori | 2001 |
Factor-VIII consumption in pre-eclampsia.
Topics: Adult; Antigens; Blood Coagulation Disorders; Factor VIII; Female; Fetal Death; Humans; Pre-Eclampsi | 1977 |
Clinical relevance of coagulation and renal changes in pre-eclampsia.
Topics: Adult; Blood Cell Count; Blood Coagulation; Blood Platelets; Creatinine; Factor VIII; Female; Fibrin | 1978 |
[Methods for the early recognition of gestosis].
Topics: Angiotensin II; Embryo Implantation; Female; Humans; Hypertension; Methods; Pre-Eclampsia; Pregnancy | 1979 |
[The prognostic value of raised uric acid in the blood in arterial hypertension in pregnancy. 58 cases (author's transl)].
Topics: Adult; Female; Humans; Hypertension; Hypertension, Renovascular; Pre-Eclampsia; Pregnancy; Pregnancy | 1979 |
[Relation between serum uric acid and blood pressure in pregnancy].
Topics: Blood Pressure; Female; Humans; Pre-Eclampsia; Pregnancy; Time Factors; Uric Acid | 1979 |
[Differential diagnosis between isolated EPH gestoses and gestoses superimposed on pre-existent nephropathies. Significance of proteinuria detected during the first weeks of pregnancy].
Topics: Creatinine; Diagnosis, Differential; Erythrocytes; Female; Humans; Kidney Diseases; Leukocytes; Pre- | 1979 |
Significance of hyperuricemia in pre-eclampsia.
Topics: Birth Weight; Female; Humans; Lactates; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Uremia; U | 1979 |
Amniotic fluid creatinine and uric acid levels in high risk pregnancy.
Topics: Amniotic Fluid; Creatinine; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Uric A | 1979 |
Plasma urate changes in pre-eclampsia.
Topics: Circadian Rhythm; Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1978 |
Plasma urate and serum deoxycytidylate deaminase measurements for the early diagnosis of pre-eclampsia.
Topics: Blood Pressure; DCMP Deaminase; Female; Humans; Nucleotide Deaminases; Pre-Eclampsia; Pregnancy; Tim | 1977 |
[The clinical significance of hyperuricemia for the prognosis of pregnancy toxemia].
Topics: Abortion, Spontaneous; Cesarean Section; Creatinine; Female; Fetal Death; Glomerular Filtration Rate | 1978 |
Early platelet consumption in pre-eclampsia.
Topics: Adult; Blood Cell Count; Blood Platelets; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimes | 1978 |
Plasma urate changes in pre-eclampsia.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1978 |
Metabolism of uric acid in normal and toxemic pregnancy.
Topics: Eclampsia; Female; Glomerular Filtration Rate; Humans; Kidney; Pre-Eclampsia; Pregnancy; Uric Acid | 1978 |
[Value of serum uric acid determination in pregnant women with EPH-gestosis in the evaluation of fetal risk].
Topics: Birth Weight; Female; Fetal Viability; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Risk; Uric | 1978 |
Renal tubular secretion of urate in sheep.
Topics: Animals; Female; Inulin; Kidney Tubules; Pre-Eclampsia; Pregnancy; Sheep; Uric Acid | 1978 |
[Hyperuricacidemia as a diagnostic sign of late pregnancy toxemia].
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Uric Acid | 1977 |
Hyperuricemia in pre-eclampsia. A reappraisal.
Topics: Absorption; Chronic Disease; Creatinine; Extracellular Space; Female; Glomerular Filtration Rate; Hu | 1976 |
[Changes of biochemical indicators of blood serum in late pregnancy toxemia].
Topics: Adolescent; Adult; Alkaline Phosphatase; Blood Proteins; Blood Urea Nitrogen; Electrolytes; Female; | 1976 |
Uric acid in pregnancy and toxaemia.
Topics: Adult; Eclampsia; Female; Humans; Longitudinal Studies; Pre-Eclampsia; Pregnancy; Uric Acid | 1976 |
Abnormal renal urate homeostasis in systemic disorders.
Topics: Alcoholism; Diabetes Mellitus; Female; Fructose Intolerance; Glomerular Filtration Rate; Glycogen St | 1975 |
Renal function in preeclampsia.
Topics: Adolescent; Adult; Female; Humans; Kidney; Pre-Eclampsia; Pregnancy; Proteinuria; Urea; Uric Acid | 1976 |
Prolactin in hypertensive pregnancy.
Topics: Edema; Female; Humans; Hypertension; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, | 1975 |
Progesterone therapy in pre-eclamptic toxaemia.
Topics: Blood Pressure; Body Weight; Depression, Chemical; Female; Humans; Metabolic Clearance Rate; Potassi | 1975 |
[Proceedings: Normal values and samples of findings in kidney diseases].
Topics: Bacteriuria; Creatinine; Female; Glomerular Filtration Rate; Gout; Hematuria; Humans; Inulin; Kidney | 1975 |
[Nephrology in 1975].
Topics: Erythrocyte Aggregation; Female; Fibrin Fibrinogen Degradation Products; Glomerulonephritis; Humans; | 1975 |
[Usefulness of biochemical studies in EPH gestosis].
Topics: Adult; Apgar Score; Blood Proteins; Creatinine; Female; Humans; Infant, Newborn; Pre-Eclampsia; Preg | 1992 |
Short-term effect of magnesium sulfate infusion on renal function in preeclamptic women.
Topics: Adolescent; Adult; Creatinine; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; I | 1992 |
Plasma endothelin levels in preeclampsia: elevation and correlation with uric acid levels and renal impairment.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Endothelins; Female; Humans; Kidney; Pre-Eclampsia; P | 1992 |
[Kidney diseases associated with pregnancy toxemia].
Topics: Blood Coagulation Disorders; Female; Humans; Hypertension; Kidney; Kidney Diseases; Pre-Eclampsia; P | 1992 |
Racial variation in serum uric acid concentration in pregnancy: a comparison between European, New Zealand Maori and Polynesian women.
Topics: Adolescent; Adult; Female; Humans; Native Hawaiian or Other Pacific Islander; New Zealand; Polynesia | 1992 |
Uric acid in pregnancy and preeclampsia: an alternative hypothesis.
Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Prospective Studies; Uric Acid | 1991 |
Erythropoietin in preeclampsia.
Topics: Adult; Albuminuria; Blood Cell Count; Blood Pressure; Creatine; Erythropoietin; Female; Humans; Pre- | 1991 |
Serum calcium, urea and uric acid levels in pre-eclampsia.
Topics: Adolescent; Adult; Blood Pressure; Calcium; Case-Control Studies; Creatinine; Female; Gestational Ag | 1991 |
Perinatal morbidity and mortality in pregnancy hypertensive disorders: prognostic value of the clinical and laboratory findings.
Topics: Adult; Albuminuria; Estriol; Female; Fetal Growth Retardation; Gestational Age; Hematocrit; Humans; | 1990 |
The relationship between autoantibodies and intrauterine growth retardation in hypertensive disorders of pregnancy.
Topics: Adult; Autoantibodies; Blood Pressure; Creatinine; DNA; Female; Fetal Growth Retardation; Gestationa | 1991 |
[Significance of determination of platelet count and serum uric acid level in preeclamptic women: report of 2 cases].
Topics: Adult; Female; Fetal Monitoring; Humans; Labor, Obstetric; Platelet Count; Pre-Eclampsia; Pregnancy; | 1991 |
Biochemical evaluation of fetus with hypoxia caused by severe preeclampsia using cordocentesis.
Topics: Adult; Blood Pressure; Carbon Dioxide; Epinephrine; Female; Fetal Blood; Fetal Hypoxia; Heart Rate, | 1990 |
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies.
Topics: Adult; Blood Pressure; Endothelins; Female; Humans; Labor, Obstetric; Pre-Eclampsia; Pregnancy; Pros | 1990 |
Proteinuria and outcome of 444 pregnancies complicated by hypertension.
Topics: Adult; Birth Weight; Female; Fetal Death; Humans; Hypertension; Infant, Newborn; Infant, Small for G | 1990 |
Significance of uric acid clearance in preeclampsia.
Topics: Female; Humans; Metabolic Clearance Rate; Pre-Eclampsia; Pregnancy; Uric Acid | 1990 |
Thrombocytopenia and platelet functional defects in pre-eclampsia: implications for regional anaesthesia.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Blood Coagulation Tests; Blood Platelets; Female; F | 1990 |
The value of Doppler assessment of the uteroplacental circulation in predicting preeclampsia or intrauterine growth retardation.
Topics: Blood Flow Velocity; Female; Fetal Growth Retardation; Humans; Placenta; Pre-Eclampsia; Predictive V | 1990 |
beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) in obstetrical cases.
Topics: Adult; Beta-Globulins; beta-Thromboglobulin; Blood Urea Nitrogen; Creatinine; Female; Humans; Male; | 1985 |
Hepatocellular lipofuscin in pre-eclampsia.
Topics: Female; Free Radicals; Humans; Lipofuscin; Liver; Oxygen; Pigments, Biological; Pre-Eclampsia; Pregn | 1989 |
Early alterations of renal function in insulin-dependent diabetic pregnancies and their importance in predicting pre-eclamptic toxaemia.
Topics: Adult; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Female; Glycated Hemogl | 1989 |
Purine metabolites as measures of birth asphyxia and predictors of brain damage.
Topics: Adult; Asphyxia Neonatorum; Brain Diseases; Female; Humans; Hypoxanthines; Infant, Newborn; Male; Pr | 1989 |
[Kidney function in women with pregnancy-induced hypertension].
Topics: Acid-Base Equilibrium; Blood Urea Nitrogen; Creatinine; Female; Humans; Kidney; Kidney Function Test | 1989 |
[Assessment of edema in pregnancy].
Topics: Adult; Albuminuria; Birth Weight; Blood Urea Nitrogen; Creatinine; Female; Gestational Age; Humans; | 1989 |
[Urinary calcium excretion in toxemia of pregnancy].
Topics: Calcium; Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1989 |
A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
Topics: Adult; Aldosterone; Cardenolides; Catecholamines; Digoxin; Female; Humans; Hypertension; Natriuretic | 1988 |
Atrial natriuretic peptide and arginine vasopressin in pregnancy and pregnancy-induced hypertension.
Topics: Adult; Arginine Vasopressin; Atrial Natriuretic Factor; Creatinine; Female; Humans; Pre-Eclampsia; P | 1988 |
The relation of angiotensin-converting enzyme to the pregnancy-induced hypertension-preeclampsia syndrome.
Topics: Adult; Arteries; Birth Weight; Blood Pressure; Blood Urea Nitrogen; Chronic Disease; Female; Fetal B | 1986 |
Uric acid levels: a useful index of the severity of preeclampsia and perinatal prognosis.
Topics: Birth Weight; Female; Humans; Hypertension; Infant, Newborn; Infant, Small for Gestational Age; Pre- | 1988 |
Progesterone increases glomerular filtration rate, urinary kallikrein excretion and uric acid clearance in normal women.
Topics: Female; Glomerular Filtration Rate; Humans; Kallikreins; Kidney; Pre-Eclampsia; Pregnancy; Progester | 1988 |
The mechanism of reduced antithrombin III activity in women with preeclampsia.
Topics: Antithrombin III; Creatinine; Female; Fibrinopeptide A; Humans; Platelet Count; Pre-Eclampsia; Pregn | 1988 |
Serum urate, complement 3 and pre-eclampsia in patients with systemic lupus erythematosus.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Complement C3; Female; Humans; Hypertension; Lupus | 1988 |
[Uric acid clearance in preeclampsia].
Topics: Adult; Female; Humans; Metabolic Clearance Rate; Pre-Eclampsia; Pregnancy; Uric Acid | 1988 |
[A study of predicting toxemia of pregnancy].
Topics: Blood Pressure; Blood Proteins; Blood Urea Nitrogen; Creatinine; Female; Humans; Pre-Eclampsia; Preg | 1987 |
[Biochemical research on the amniotic fluid and a morphological evaluation of the placenta in women with pregnancy toxicosis].
Topics: Adult; Amniotic Fluid; Electrolytes; Enzymes; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Ur | 1987 |
Serum uric acid correlates with beta 2-microglobulin in pre-eclampsia.
Topics: Adult; beta 2-Microglobulin; Female; Humans; Kidney Tubules; Pre-Eclampsia; Pregnancy; Uric Acid | 1986 |
[Preeclampsia and tubular dysfunction].
Topics: beta 2-Microglobulin; Chlorine; Female; Humans; Kidney Tubules; Pre-Eclampsia; Pregnancy; Sodium; Ur | 1987 |
The placental transfer and concentration difference in maternal and neonatal serum uric acid at parturition: comparison of normal pregnancies and gestosis.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Maternal-Fetal Exchange; Pre-Eclamps | 1987 |
[Usefulness of determining free estriol, placental lactogen, progesterone, placental alkaline phosphatase, uric acid, hematocrit, hemoglobin and proteins in the blood and estrogen in the urine in the prognosis of the status of newborn infants in EPH gesto
Topics: Alkaline Phosphatase; Estrogens; Female; GPI-Linked Proteins; Hematocrit; Hemoglobins; Humans; Infan | 1987 |
Prolactin in severe toxemia of pregnancy.
Topics: Blood Urea Nitrogen; Female; Gestational Age; Humans; Pre-Eclampsia; Pregnancy; Prolactin; Uric Acid | 1986 |
Plasma concentration of urate, urea and creatinine in Nigerian primigravidae with pre-eclampsia.
Topics: Adolescent; Adult; Creatinine; Female; Humans; Nigeria; Parity; Pre-Eclampsia; Pregnancy; Urea; Uric | 1986 |
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor | 1985 |
Platelets and uric acid in the prediction of preeclampsia.
Topics: Blood Platelets; Blood Pressure; Blood Volume; Female; Humans; Platelet Count; Pre-Eclampsia; Pregna | 1985 |
[Evaluation of the clinical and biologic means of assessing fetal prognosis in pregnancy toxemias. Apropos of 223 cases].
Topics: Blood Coagulation Disorders; Blood Pressure; Body Weight; Circadian Rhythm; Edema; Female; Fetal Dis | 1985 |
[Early diagnosis, prevention and basic pathology of EPH gestosis].
Topics: Brain Edema; Diet, Sodium-Restricted; Edema; Energy Intake; Female; Humans; Hypertension; Pre-Eclamp | 1985 |
[Pregnancy and hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Maternal-Fetal Exchange; Pre- | 1985 |
Hypertension and hyperuricaemia.
Topics: Adolescent; Adult; Aged; Blood; Cerebrovascular Disorders; Cobalt Isotopes; Coronary Disease; Female | 1966 |
[Therapy of late gestational toxicosis using Briserin].
Topics: Amides; Blood Pressure; Chlorine; Clopamide; Creatinine; Delivery, Obstetric; Diuretics; Drug Combin | 1973 |
[Metabolism of water and sodium during normal pregnancy and pregnancy toxemia].
Topics: Aldosterone; Angiotensin II; Female; Humans; Pre-Eclampsia; Pregnancy; Renin; Sodium; Uric Acid; Vas | 1972 |
Renal function in pregnancy.
Topics: Aldosterone; Angiotensin II; Catecholamines; Estrogens; Female; Glomerular Filtration Rate; Glycosur | 1972 |
The effect of frusemide on uric acid levels in maternal blood, fetal blood and amniotic fluid.
Topics: Amniotic Fluid; Blood; Female; Furosemide; Humans; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy | 1974 |
Serum uric acid in late pregnancy in normal and toxaemic patients. Comparison with the variations in the oxytocinase, oestriol, alkaline phosphatase and heat-stable alkaline phosphatase values.
Topics: Alkaline Phosphatase; Aminopeptidases; Estriol; Female; Humans; Oxytocin; Pre-Eclampsia; Pregnancy; | 1972 |
Simultaneous measurement of plasma and erythrocyte oxypurines. I. Normal and toxemic pregnancy.
Topics: Blood; Carbon Isotopes; Chromatography, Gel; Erythrocytes; Female; Humans; Hypoxanthines; Labor, Obs | 1972 |
Management of renal disease in pregnancy.
Topics: Acute Disease; Anti-Infective Agents, Urinary; Bacteriuria; Chronic Disease; Diabetic Nephropathies; | 1972 |
Amniotic fluid levels of uric acid and creatinine in toxemic patients--possible relation to diuretic use.
Topics: Amniocentesis; Amniotic Fluid; Autoanalysis; Chlorothiazide; Creatinine; Diuretics; Female; Humans; | 1973 |
Pregnancy bacteriuria: the significance of site of infection.
Topics: Anemia; Antibodies, Bacterial; Bacteriuria; Female; Fetal Death; Humans; Hypertension; Kidney Diseas | 1973 |
A critical evaluation of renal protein selectivity in pregnancy.
Topics: Creatinine; Female; Fetal Death; Humans; Hypertension; Immunoglobulin G; Kidney; Molecular Weight; P | 1974 |
[Uric acid in the toxemic patient].
Topics: Adult; Female; Humans; Maternal Age; Parity; Pre-Eclampsia; Pregnancy; Uric Acid | 1974 |
The pregnant Natal Indian diabetic.
Topics: Adolescent; Adrenal Glands; Adult; Blood Glucose; Body Height; Body Weight; Cholesterol; Escherichia | 1969 |
Laboratory characteristics in toxemia.
Topics: Blood Glucose; Blood Proteins; Calcium; Cerebrospinal Fluid Proteins; Color; Erythrocytes; Female; G | 1972 |
Effects of hypotonic expansion on sodium and water excretion in hypertensive non-pre-eclamptic gravidas.
Topics: Aminohippuric Acids; Diuresis; Extracellular Space; Female; Humans; Hypertension; Hypotonic Solution | 1971 |
[Relation between uric acid and urea in blood (index), its value in the early diagnosis of renal insufficiency and its use].
Topics: Acute Kidney Injury; Blood Urea Nitrogen; Female; Humans; Male; Pre-Eclampsia; Pregnancy; Uric Acid | 1970 |
Lactic acid and hyperuricemia of faulty renal urate transport.
Topics: Female; Glycogen Storage Disease; Gout; Humans; Hypertension; Kidney Diseases; Lactates; Pre-Eclamps | 1967 |
An evaluation of serum uric acid estimations in toxaemia of pregnancy.
Topics: Female; Humans; Hypertension; Male; Pre-Eclampsia; Pregnancy; Uric Acid | 1968 |
[Diagnostic value of hyperuricemia].
Topics: Adult; Allopurinol; Child; Diabetes Mellitus; Female; Glycogen Storage Disease; Gout; Humans; Hypert | 1968 |
Serum uric acid in pre-eclampsia and eclampsia.
Topics: Blood Urea Nitrogen; Eclampsia; Female; Humans; Pre-Eclampsia; Pregnancy; Uric Acid | 1969 |
Blood uric acid level in pregnancy.
Topics: Female; Humans; Obstetric Labor Complications; Pre-Eclampsia; Pregnancy; Uric Acid | 1969 |
Sodium depletion simulating deterioration in a toxemic pregnancy.
Topics: Adult; Diagnosis, Differential; Diet; Diet, Sodium-Restricted; Female; Glomerular Filtration Rate; H | 1970 |
Concentrations of uric acid in the serum of neonatal infants and their mothers.
Topics: Delivery, Obstetric; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Physical Examin | 1970 |
Evaluation of new tools for the differential diagnosis of toxaemia of pregnancy.
Topics: Adult; Biopsy; Diagnosis, Differential; Female; Fundus Oculi; Humans; Kidney; Kidney Function Tests; | 1970 |
[Value of blood uric acid determination during pregnancy].
Topics: Chlorothiazide; Eclampsia; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Funct | 1968 |
Evaluation of renal biopsy in pregnancy toxemia.
Topics: Adolescent; Adult; Biopsy; Blood Urea Nitrogen; Creatinine; Female; Gestational Age; Humans; Hyperte | 1969 |
Ultrastructural studies in hypertension. IV. Toxemia of pregnancy.
Topics: Biopsy; Blood Urea Nitrogen; Capillaries; Creatinine; Female; Hypertension; Juxtaglomerular Apparatu | 1969 |