Page last updated: 2024-10-20

uric acid and Pneumonia

uric acid has been researched along with Pneumonia in 12 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"The molecular mechanisms by which lung injury triggers IL-1beta production, inflammation, and fibrosis remain poorly understood."1.35Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. ( Charron, S; Couillin, I; Fick, L; Gasse, P; Girre, S; Lagente, V; Pétrilli, V; Quesniaux, VF; Riteau, N; Ryffel, B; Tschopp, J, 2009)
"Patients without pneumonitis had a significantly higher RVSP value than those with pneumonitis (77."1.33Pulmonary arterial hypertension in autoimmune diseases: an analysis of 19 cases from a medical center in northern Taiwan. ( Chen, CH; Chen, HA; Chou, CT; Huang, DF; Liao, HT; Wang, HP, 2006)
"An occasional child will have marked leukocytosis and disturbance of organ function due to massive leukemic infiltrates."1.25Complications and total care of a child with acute leukemia. ( Ragab, AH; Vietti, TJ, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Højen, JF1
Kristensen, MLV1
McKee, AS1
Wade, MT1
Azam, T1
Lunding, LP1
de Graaf, DM1
Swartzwelter, BJ1
Wegmann, M1
Tolstrup, M1
Beckman, K1
Fujita, M1
Fischer, S1
Dinarello, CA1
Wu, J1
Yan, Z1
Schwartz, DE1
Yu, J1
Malik, AB1
Hu, G2
Hara, K1
Iijima, K1
Elias, MK1
Seno, S1
Tojima, I1
Kobayashi, T1
Kephart, GM1
Kurabayashi, M1
Kita, H1
Song, C1
He, L1
Zhang, J2
Ma, H1
Yuan, X1
Tao, L1
Meng, J1
Gasse, P1
Riteau, N1
Charron, S1
Girre, S1
Fick, L1
Pétrilli, V1
Tschopp, J1
Lagente, V1
Quesniaux, VF1
Ryffel, B2
Couillin, I2
BANERJEE, PK1
Gibbings, S1
Elkins, ND1
Fitzgerald, H1
Tiao, J1
Weyman, ME1
Shibao, G1
Fini, MA1
Wright, RM1
Besnard, AG1
Togbe, D1
Tan, Z1
Zheng, SG1
Erard, F1
Le Bert, M1
Quesniaux, V1
Chen, CH1
Chen, HA1
Wang, HP1
Liao, HT1
Chou, CT1
Huang, DF1
Aejmelaeus, R1
Metsä-Ketelä, T1
Laippala, P1
Alho, H1
Vietti, TJ1
Ragab, AH1
Quigley, MM1

Reviews

1 review available for uric acid and Pneumonia

ArticleYear
Inflammasome-IL-1-Th17 response in allergic lung inflammation.
    Journal of molecular cell biology, 2012, Volume: 4, Issue:1

    Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Cell Differentiation; Inflammasomes; Interleukin-

2012

Other Studies

11 other studies available for uric acid and Pneumonia

ArticleYear
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
    Nature immunology, 2019, Volume: 20, Issue:9

    Topics: A549 Cells; Animals; Antibodies, Blocking; Antibodies, Monoclonal; Cell Line, Tumor; Disease Models,

2019
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-01, Volume: 190, Issue:7

    Topics: Animals; Carrier Proteins; Caspase 1; Disease Models, Animal; Inflammasomes; Interleukin-18; Interle

2013
Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa.
    Journal of immunology (Baltimore, Md. : 1950), 2014, May-01, Volume: 192, Issue:9

    Topics: Adaptive Immunity; Allergens; Animals; Bromelains; Cytokines; Disease Models, Animal; Enzyme-Linked

2014
Fluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP3 inflammasome and IL-1β/IL-1R1/MyD88/NF-κB pathway.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:11

    Topics: Actins; Animals; Bleomycin; Caspase 1; Chemokine CCL2; Collagen Type I; Down-Regulation; Fibronectin

2016
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.
    American journal of respiratory and critical care medicine, 2009, May-15, Volume: 179, Issue:10

    Topics: Allopurinol; Animals; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Carrier Proteins; Disease

2009
Blood uric acid and chloride in thirty cases of pneumonia.
    Indian medical journal, 1946, Volume: 40

    Topics: Blood; Chlorides; Humans; Ions; Pneumonia; Uric Acid

1946
Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}.
    The Journal of biological chemistry, 2011, Jan-14, Volume: 286, Issue:2

    Topics: Animals; Cell Differentiation; Chemokine CXCL1; Chemokines; Enzyme Activation; HL-60 Cells; Humans;

2011
Pulmonary arterial hypertension in autoimmune diseases: an analysis of 19 cases from a medical center in northern Taiwan.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2006, Volume: 39, Issue:2

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoimmune Diseases; Female; Hospitals; Humans; Hypergammaglob

2006
Is there an unidentified defence mechanism against infection in human plasma?
    FEBS letters, 1996, Apr-15, Volume: 384, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Cefuroxime; Female; Free Radical Scaven

1996
Complications and total care of a child with acute leukemia.
    Cancer, 1975, Volume: 35, Issue:3 suppl

    Topics: Acute Disease; Adolescent; Agranulocytosis; Anemia; Antineoplastic Agents; Bacterial Infections; Bon

1975
Acute obstetric yellow atrophy presenting as idiopathic hyperuricemia.
    Southern medical journal, 1974, Volume: 67, Issue:2

    Topics: Acute Kidney Injury; Adult; Blood Coagulation Tests; Bronchopneumonia; Cytoplasm; Diagnosis, Differe

1974