Page last updated: 2024-10-20

uric acid and Peripheral Arterial Disease

uric acid has been researched along with Peripheral Arterial Disease in 9 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Peripheral Arterial Disease: Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.

Research Excerpts

ExcerptRelevanceReference
"Higher serum uric acid (SUA) can cause gout, which is principally characterized by arthritis due to monosodium urate crystal deposition in the lower extremities."8.31Association between serum uric acid levels and peripheral artery disease in Chinese adults with hypertension. ( Bao, H; Cheng, X; Han, F; Hu, F; Huang, X; Wang, T; Yu, C; Zhou, W; Zhu, L, 2023)
"Uric acid levels are associated with the degree of leg ischemia in patients with PAD."7.85Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment. ( Hirooka, S; Orita, H; Sotoda, Y; Wakabayashi, I, 2017)
"To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes."7.81Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015)
"Multiterritorial atherosclerosis has dramatically increased annual risk of adverse cardiovascular events than atherosclerotic disease with single-artery affected."5.51Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis. ( Chen, J; Cheng, W; Cui, Q; Geng, B; Li, N; Song, M; Wang, K; Wang, Y; Yang, J; Yao, Y; Zhou, Y, 2019)
"Higher serum uric acid (SUA) can cause gout, which is principally characterized by arthritis due to monosodium urate crystal deposition in the lower extremities."4.31Association between serum uric acid levels and peripheral artery disease in Chinese adults with hypertension. ( Bao, H; Cheng, X; Han, F; Hu, F; Huang, X; Wang, T; Yu, C; Zhou, W; Zhu, L, 2023)
"Uric acid levels are associated with the degree of leg ischemia in patients with PAD."3.85Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment. ( Hirooka, S; Orita, H; Sotoda, Y; Wakabayashi, I, 2017)
"To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes."3.81Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015)
" Endpoints were defined as major adverse limb events (MALE; target vessel revascularization, amputation, or disease progression) and major adverse cardiovascular events (MACE; stroke, myocardial infarction, or all-cause death) during the entire follow-up period."1.72C-reactive Protein, Free Fatty Acid, and Uric Acid as Predictors of Adverse Events after Endovascular Revascularization of Arterial Femoropopliteal Occlusion Lesions. ( Di, X; Han, W; Liu, C; Zhang, R; Zheng, Y, 2022)
"Multiterritorial atherosclerosis has dramatically increased annual risk of adverse cardiovascular events than atherosclerotic disease with single-artery affected."1.51Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis. ( Chen, J; Cheng, W; Cui, Q; Geng, B; Li, N; Song, M; Wang, K; Wang, Y; Yang, J; Yao, Y; Zhou, Y, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Di, X1
Han, W1
Zhang, R2
Liu, C1
Zheng, Y1
Han, F1
Yu, C1
Hu, F1
Zhou, W1
Wang, T1
Zhu, L1
Huang, X1
Bao, H1
Cheng, X1
Taher, R1
Sara, JD1
Prasad, M1
Kolluri, N1
Toya, T1
Lerman, LO1
Lerman, A1
Chen, SC1
Lee, MY1
Huang, JC1
Mai, HC1
Kuo, PL1
Chang, JM1
Chen, HC1
Yang, YH1
Song, M1
Li, N1
Yao, Y1
Wang, K1
Yang, J1
Cui, Q1
Geng, B1
Chen, J1
Wang, Y1
Cheng, W1
Zhou, Y1
Li, LX1
Lu, JX1
Shuai, HP1
Xia, HF1
Wang, JW1
Chen, MY1
Li, TT1
Bao, YQ1
Jia, WP1
Hamur, H1
Onk, OA1
Vuruskan, E1
Duman, H1
Bakirci, EM1
Kucuksu, Z1
Degirmenci, H1
Buyuklu, M1
Topal, E1
Sotoda, Y1
Hirooka, S1
Orita, H1
Wakabayashi, I1
Endo, M1
Kumakura, H1
Kanai, H1
Araki, Y1
Kasama, S1
Sumino, H1
Ichikawa, S1
Kurabayashi, M1

Trials

1 trial available for uric acid and Peripheral Arterial Disease

ArticleYear
Association of diabetes mellitus with decline in ankle-brachial index among patients on hemodialysis: A 6-year follow-up study.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Adult; Aged; Ankle Brachial Index; Blood Pressure; Creatinine; Diabetes Mellitus; Female; Follow-Up

2017

Other Studies

8 other studies available for uric acid and Peripheral Arterial Disease

ArticleYear
C-reactive Protein, Free Fatty Acid, and Uric Acid as Predictors of Adverse Events after Endovascular Revascularization of Arterial Femoropopliteal Occlusion Lesions.
    Annals of vascular surgery, 2022, Volume: 81

    Topics: Aged; C-Reactive Protein; Fatty Acids, Nonesterified; Female; Humans; Kaplan-Meier Estimate; Limb Sa

2022
Association between serum uric acid levels and peripheral artery disease in Chinese adults with hypertension.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; East Asian People; Female; Gout; Humans; Hy

2023
Elevated serum uric acid is associated with peripheral endothelial dysfunction in women.
    Atherosclerosis, 2019, Volume: 290

    Topics: Adult; Biomarkers; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Hyperemia; Hyperu

2019
Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

    Topics: Adult; Arteries; Asian People; Atherosclerosis; Cohort Studies; Constriction, Pathologic; Female; Hu

2019
Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes.
    Atherosclerosis, 2015, Volume: 242, Issue:1

    Topics: Aged; Alcohol Drinking; Biomarkers; China; Comorbidity; Constriction, Pathologic; Cross-Sectional St

2015
Determinants of Chronic Total Occlusion in Patients With Peripheral Arterial Occlusive Disease.
    Angiology, 2017, Volume: 68, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Bilirubin; Biomarkers; C-Reactive Prote

2017
Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment.
    Journal of atherosclerosis and thrombosis, 2017, Jul-01, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Biomarkers; Carotid Intima-Media Thickness; Exercise

2017
Prevalence and risk factors for renal artery stenosis and chronic kidney disease in Japanese patients with peripheral arterial disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Albuminuria; Angiography; Asian People; Cholesterol, LDL; Como

2010