uric acid has been researched along with Osteolysis in 2 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is now well established that intra-articular deposition of endogenous particulates, such as osteoarthritis-associated basic calcium phosphate crystals, gout-associated monosodium urate crystals, and calcium deposition disease-associated calcium pyrophosphate crystals, contributes to joint destruction through the production of cartilage-degrading enzymes and pro-inflammatory cytokines." | 4.98 | Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets. ( Dunne, A; Mahon, OR, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahon, OR | 1 |
| Dunne, A | 1 |
| Uhl, M | 1 |
1 review available for uric acid and Osteolysis
| Article | Year |
|---|---|
Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets.
Topics: Animals; Arthritis; Biomarkers; Calcium Pyrophosphate; Crystal Arthropathies; Disease Susceptibility | 2018 |
1 other study available for uric acid and Osteolysis
| Article | Year |
|---|---|
[Radiology of the skeleton of the hand. 2. Degenerative joint diseases. Endocrine and metabolic bone diseases].
Topics: Arthritis; Arthritis, Rheumatoid; Bone Diseases; Chondrocalcinosis; Hand; Hemoglobinopathies; Humans | 1999 |