uric acid has been researched along with Osteoarthritis in 108 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind multiclinic trial, a new nonsteroidal anti-inflammatory agent (ibuprofen) was compared with an established therapeutic agent (phenylbutazone-alka) for the treatment of osteoarthritis." | 9.04 | Ibuprofen versus buffered phenylbutazone in the treatment of osteoarthritis: double-blind trial. ( Donovan, JF; Hearron, MS; Levi, L; Moxley, TE; Royer, GL, 1975) |
| "There is an ongoing debate regarding the relationship between uric acid and osteoarthritis (OA)." | 7.88 | Serum uric acid level is not associated with osteoarthritis in Korean population: data from the Seventh Korea National Health and Nutrition Examination Survey 2016. ( Choe, JY; Kim, SK; Kwak, SG, 2018) |
| "The main aim of this study was to investigate the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid (SF) obtained from patients with previously diagnosed joint diseases." | 7.79 | Prevalence of calcium pyrophosphate and monosodium urate crystals in synovial fluid of patients with previously diagnosed joint diseases. ( Frallonardo, P; Galozzi, P; Gava, A; Oliviero, F; Punzi, L; Ramonda, R; Scanu, A, 2013) |
| "To assess the association between uric acid and patterns of osteoarthritis (OA)." | 7.70 | Serum uric acid and patterns of radiographic osteoarthritis--the Ulm Osteoarthritis Study. ( Brenner, H; Günther, KP; Puhl, W; Sauerland, S; Stürmer, T; Sun, Y, 2000) |
| "The potential antinociceptive effects of the S(+)- and R(-)-enantiomers of flurbiprofen (SFB and RFB, respectively) were investigated when given intravenously to rats using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 7.70 | Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain. ( Cabré, F; Díaz, MI; Domínguez, AM; García, ML; Hernández, GP; López-Muñoz, FJ; Mauleón, D; Ventura, R, 2000) |
| "Urate crystal gout arthritis and calcium pyrophosphate deposition disease (CPPD) are crystalline arthropathies seen in middle age to elderly patients, but are also seen in the active duty military population." | 5.41 | 20 Years of Radiographic Imaging: Crystalline Deposits Causing Severe Arthropathy and Erosions. ( Babb, S; Breighner, C; Goldstein, E; Mank, VMF; Meghpara, S; Roberts, J, 2023) |
| " Each dose was given for 14 days and diflunisal apparent oral clearance and serum urate was measured on the last day of each dosing regimen." | 5.27 | Diflunisal disposition and hypouricemic response in osteoarthritis. ( Bertouch, J; Brooks, PM; Harrington, BJ; Meffin, PJ; Veenendaal, JR, 1983) |
| "In a double-blind multiclinic trial, a new nonsteroidal anti-inflammatory agent (ibuprofen) was compared with an established therapeutic agent (phenylbutazone-alka) for the treatment of osteoarthritis." | 5.04 | Ibuprofen versus buffered phenylbutazone in the treatment of osteoarthritis: double-blind trial. ( Donovan, JF; Hearron, MS; Levi, L; Moxley, TE; Royer, GL, 1975) |
| " The main pathogens are crystals of monosodium urate (MSU), responsible for the gout, calcium pyrophosphate (CPP), which deposits also in various clinical forms of arthopathies, and basic calcium phosphate associated with osteoarthritis." | 4.90 | Pain and microcrystalline arthritis. ( Frallonardo, P; Lorenzin, MG; Oliviero, F; Ortolan, A; Punzi, L; Ramonda, R; Scanu, A, 2014) |
| " Serum uric acid (UA) is a terminal metabolite of purine compound, while hyperuricemia (HU) and UA crystals are recognized causes of gout." | 3.96 | Association between hyperuricemia, gout, urate lowering therapy, and osteoarthritis: A protocol for a systematic review and meta-analysis. ( Chen, Y; Li, H; Li, X; Wang, Y; Yang, Z; Zhu, J, 2020) |
| "There is an ongoing debate regarding the relationship between uric acid and osteoarthritis (OA)." | 3.88 | Serum uric acid level is not associated with osteoarthritis in Korean population: data from the Seventh Korea National Health and Nutrition Examination Survey 2016. ( Choe, JY; Kim, SK; Kwak, SG, 2018) |
| "A metabolic syndrome (MetS) is accompanied by hyperuricemia, during which xanthine oxidoreductase (XOR) catalyzes the production of uric acid." | 3.83 | Xanthine oxidoreductase activation is implicated in the onset of metabolic arthritis. ( Aibibula, Z; Ailixiding, M; Asou, Y; Hara, Y; Iwata, M; Okawa, A; Piao, J, 2016) |
| " Caspase-1, IL-1β, IL-18, and uric acid were measured in synovial fluid from 112 patients with gout and other arthritides, such as rheumatoid arthritis, osteoarthritis, and spondyloarthropathy." | 3.79 | Caspase-1 level in synovial fluid is high in patients with spondyloarthropathy but not in patients with gout. ( Bang, SY; Choi, CB; Jun, JB; Kim, JH; Kim, TH; Son, CN, 2013) |
| "The main aim of this study was to investigate the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid (SF) obtained from patients with previously diagnosed joint diseases." | 3.79 | Prevalence of calcium pyrophosphate and monosodium urate crystals in synovial fluid of patients with previously diagnosed joint diseases. ( Frallonardo, P; Galozzi, P; Gava, A; Oliviero, F; Punzi, L; Ramonda, R; Scanu, A, 2013) |
| "We estimated xanthine oxidase (XA), xanthine dehydrogenase (XDG), 5'-nucleotidase (5'-NT) activity, esoenzymes of XDG and content of uric acid (UA) in the sera of 44 patients with osteoarthritis and 34 patients with gout arthritis." | 3.70 | [Purine metabolism enzymes in diagnosis and differential diagnosis of osteoarthritis and gout arthritis]. ( Martem'ianov, VF; Stazharov, MIu; Zborovskiĭ, AB, 2000) |
| "To assess the association between uric acid and patterns of osteoarthritis (OA)." | 3.70 | Serum uric acid and patterns of radiographic osteoarthritis--the Ulm Osteoarthritis Study. ( Brenner, H; Günther, KP; Puhl, W; Sauerland, S; Stürmer, T; Sun, Y, 2000) |
| "The potential antinociceptive effects of the S(+)- and R(-)-enantiomers of flurbiprofen (SFB and RFB, respectively) were investigated when given intravenously to rats using the pain-induced functional impairment model in the rat (PIFIR), an animal model of arthritic pain." | 3.70 | Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain. ( Cabré, F; Díaz, MI; Domínguez, AM; García, ML; Hernández, GP; López-Muñoz, FJ; Mauleón, D; Ventura, R, 2000) |
| " The three main types of crystal arthritis are monosodium urate (gout), calcium pyrophosphate dihydrate, and calcium phosphate (usually hydroxyapatite)." | 3.68 | Crystal arthritis: a clinician's view. ( Hall, S, 1991) |
| "The effect of serum and synovial fluid obtained from six healthy subjects and from 12 patients with gout, six with rheumatoid arthritis and 18 with calcium pyrophosphate dihydrate arthropathy (CPPD) on the rate of in vitro urate crystal formation was measured." | 3.68 | Evidence for a promoter of urate crystal formation in gouty synovial fluid. ( Dieppe, PA; McGill, NW, 1991) |
| " This link between obesity and subsequent osteoarthritis persisted after controlling for serum uric acid level and physical activity level, and was strongest for persons with severest radiographic disease." | 3.67 | Obesity and knee osteoarthritis. The Framingham Study. ( Anderson, JJ; Felson, DT; Meenan, RF; Naimark, A; Walker, AM, 1988) |
| " The association of arthritic disease and joint degeneration with the deposition of sodium urate crystals in gout and calcium pyrophosphate crystals in pseudogout (chondrocalcinosis) is clinically well established." | 3.67 | Apatite-type crystal deposition in arthritic cartilage. ( Ali, SY, 1985) |
| "Intrasynovial deposits of monourate crystals in the presence of serum hyperuricaemia, and calcium pyrophosphate dihydrate (CPPD) crystals, are responsible for gout and pseudogout respectively." | 3.66 | Crystal induced arthritis: gout and pseudogout. ( Webb, J, 1978) |
| "Osteoarthritis is the most common form of arthritis overall, and gout and osteoarthritis frequently coexist in the same patient." | 2.61 | Urate and osteoarthritis: Evidence for a reciprocal relationship. ( Krasnokutsky, S; Neogi, T; Pillinger, MH, 2019) |
| "Gout affects the structure and function of the 1(st) MTP." | 2.53 | The first metatarsophalangeal joint in gout: a systematic review and meta-analysis. ( Dalbeth, N; Rome, K; Stewart, S; Vandal, AC, 2016) |
| "In pSS patients only presenting with joint pain, arthritis patients had higher ESSDAI and system involvements, but lower UA and TG levels compared with OA group (P < 0." | 1.91 | Osteoarthritis or arthritis? Toward understanding of primary Sjögren's syndrome patients with arthralgia. ( Gao, R; Pu, J; Tang, J; Wang, X; Wu, Z, 2023) |
| "Intermittent hand joint pain was also an independent risk factor for worse general health description." | 1.51 | Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study. ( Aspelund, T; Eiriksdottir, G; Gudnason, V; Harris, TB; Jonsson, H; Launer, LJ, 2019) |
| " Each dose was given for 14 days and diflunisal apparent oral clearance and serum urate was measured on the last day of each dosing regimen." | 1.27 | Diflunisal disposition and hypouricemic response in osteoarthritis. ( Bertouch, J; Brooks, PM; Harrington, BJ; Meffin, PJ; Veenendaal, JR, 1983) |
| "Obesity was associated with both bilateral and unilateral OA, but more strongly with bilateral OA." | 1.27 | The role of metabolic factors and blood pressure in the association of obesity with osteoarthritis of the knee. ( Davis, MA; Ettinger, WH; Neuhaus, JM, 1988) |
| "Obesity has to be considered a connecting link between both of them, and it is accelerating their genesis." | 1.26 | [Hallux rigidus arthrosis and gout]. ( Mertz, DP, 1982) |
| "It is shown that in osteoarthrosis the clinical characteristics vary from one joint group to another." | 1.26 | Heberden Oration 1981: epidemiology and the arthritides. ( Acheson, RM, 1982) |
| "Osteoarthrosis (OA) scores for the hand and for all body sites were computed for each subject by summing the number of affected joints." | 1.25 | New Haven survey of joint diseases. XVII. Relationship between some systemic characteristics and osteoarthrosis in a general population. ( Acheson, RM; Collart, AB, 1975) |
| "Generalized osteoarthrosis was found to be significantly more common in older males with high than with low diastolic blood pressure." | 1.25 | Hypertension in relation to musculoskeletal disorders. ( Lawrence, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (61.11) | 18.7374 |
| 1990's | 8 (7.41) | 18.2507 |
| 2000's | 9 (8.33) | 29.6817 |
| 2010's | 17 (15.74) | 24.3611 |
| 2020's | 8 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, D | 2 |
| Xu, H | 2 |
| Sun, L | 1 |
| Li, Y | 7 |
| Wang, T | 2 |
| Jarraya, M | 1 |
| Roemer, F | 1 |
| Kwoh, CK | 1 |
| Guermazi, A | 1 |
| Gao, R | 3 |
| Pu, J | 1 |
| Wu, Z | 1 |
| Tang, J | 1 |
| Wang, X | 6 |
| Qin, H | 1 |
| Hua, Y | 1 |
| Dalbeth, N | 3 |
| Jonsson, H | 1 |
| Aspelund, T | 1 |
| Eiriksdottir, G | 1 |
| Harris, TB | 1 |
| Launer, LJ | 1 |
| Gudnason, V | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 5 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 2 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 11 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 2 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
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| Zhang, RG | 1 |
| Cai, Q | 1 |
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| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
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| Tao, F | 1 |
| Xiang, W | 1 |
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| Jin, L | 1 |
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| Ma, Q | 1 |
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| Leuschner, R | 1 |
| Magrans, JO | 1 |
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| Pedersen, R | 1 |
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| Rojas, A | 1 |
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| Wen, L | 1 |
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| Xie, X | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preoperative Resistance Training in Patients Scheduled for Total Hip Arthroplasty - a Prospective Randomized Study in Patients With Osteoarthritis[NCT01164111] | 80 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for uric acid and Osteoarthritis
| Article | Year |
|---|---|
Crystal arthropathies and osteoarthritis-where is the link?
Topics: Calcinosis; Crystal Arthropathies; Gout; Humans; Inflammation; Osteoarthritis; Uric Acid | 2023 |
Contributions of joint damage-related events to gout pathogenesis: new insights from laboratory research.
Topics: Gout; Humans; Joints; Osteoarthritis; Uric Acid | 2023 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
20 Years of Radiographic Imaging: Crystalline Deposits Causing Severe Arthropathy and Erosions.
Topics: Aged; Calcium Pyrophosphate; Chondrocalcinosis; Female; Gout; Humans; Joint Diseases; Middle Aged; O | 2023 |
Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Psoriatic; Arthritis, Rheumato | 2022 |
Urate and osteoarthritis: Evidence for a reciprocal relationship.
Topics: Biomarkers; Global Health; Humans; Hyperuricemia; Osteoarthritis; Prevalence; Uric Acid | 2019 |
Pain and microcrystalline arthritis.
Topics: Animals; Arthritis, Gouty; Calcium Pyrophosphate; Chronic Pain; Crystallization; Dinoprostone; Disea | 2014 |
The first metatarsophalangeal joint in gout: a systematic review and meta-analysis.
Topics: Gout; Humans; Metatarsophalangeal Joint; Osteoarthritis; Uric Acid | 2016 |
The role of uric acid and other crystals in osteoarthritis.
Topics: Calcium Pyrophosphate; Crystallization; Gout; Humans; Joints; Osteoarthritis; Uric Acid | 2010 |
Crystal-associated arthritis in the elderly.
Topics: Aged; Allopurinol; Arthritis; Arthritis, Gouty; Calcium Pyrophosphate; Chondrocalcinosis; Comorbidit | 2007 |
Osteoarthritis I: epidemiology.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Obesity; Osteoarthritis; Se | 1984 |
Crystal deposition in osteoarthritis: an opportunistic event?
Topics: Animals; Arthropathy, Neurogenic; Calcium Pyrophosphate; Cartilage, Articular; Cholesterol; Chondroc | 1985 |
Mixed crystal deposition.
Topics: Calcinosis; Calcium Pyrophosphate; Crystallization; Female; Gout; Humans; Joint Diseases; Middle Age | 1988 |
Medical management of the patient with arthritis.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Aspirin; Chond | 1974 |
4 trials available for uric acid and Osteoarthritis
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Ibuprofen versus buffered phenylbutazone in the treatment of osteoarthritis: double-blind trial.
Topics: Alanine Transaminase; Clinical Trials as Topic; Drug Evaluation; Humans; Ibuprofen; Osteoarthritis; | 1975 |
Clinical study of a new anti-inflammatory drug: 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370).
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Bilirubin; Blood Cell Count | 1972 |
South African multicentre trial with Voltaren in osteo-arthritis of the knee.
Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Ethnicit | 1974 |
91 other studies available for uric acid and Osteoarthritis
| Article | Year |
|---|---|
Assessing causality between osteoarthritis with urate levels and gout: a bidirectional Mendelian randomization study.
Topics: Genome-Wide Association Study; Gout; Humans; Mendelian Randomization Analysis; Osteoarthritis; Polym | 2022 |
Osteoarthritis or arthritis? Toward understanding of primary Sjögren's syndrome patients with arthralgia.
Topics: Arthralgia; Humans; Metacarpophalangeal Joint; Osteoarthritis; Sjogren's Syndrome; Uric Acid | 2023 |
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study.
Topics: Aged; Aged, 80 and over; Area Under Curve; Arthralgia; Cross-Sectional Studies; Female; Hand Joints; | 2019 |
Association between hyperuricemia, gout, urate lowering therapy, and osteoarthritis: A protocol for a systematic review and meta-analysis.
Topics: Gout; Humans; Hyperuricemia; Meta-Analysis as Topic; Observational Studies as Topic; Osteoarthritis; | 2020 |
Serum apoprotein A1 levels are inversely associated with disease activity in gout: From a southern Chinese Han population.
Topics: Adult; Apolipoprotein A-I; Arthritis, Gouty; Arthritis, Rheumatoid; Asian People; Biomarkers; Blood | 2017 |
Serum uric acid level is not associated with osteoarthritis in Korean population: data from the Seventh Korea National Health and Nutrition Examination Survey 2016.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cross-Sectional Studies; Female; Humans; Hyperuricemia; | 2018 |
Human Cartilage Homogenates Influence the Crystallization of Monosodium Urate and Inflammatory Response to Monosodium Urate Crystals: A Potential Link Between Osteoarthritis and Gout.
Topics: Cartilage; Crystallization; Cytokines; Gout; Humans; Inflammation; Knee Joint; Osteoarthritis; Uric | 2019 |
Caspase-1 level in synovial fluid is high in patients with spondyloarthropathy but not in patients with gout.
Topics: Adult; Aged; Arthritis, Rheumatoid; Caspase 1; Female; Gout; Humans; Interleukin-18; Interleukin-1be | 2013 |
A comparative study of serum and synovial fluid levels of uric acid between patients with gout and other arthritides.
Topics: Adult; Aged; Aged, 80 and over; Arthritis; Arthritis, Gouty; Arthritis, Infectious; Arthritis, Rheum | 2014 |
Xanthine oxidoreductase activation is implicated in the onset of metabolic arthritis.
Topics: Adipose Tissue; Animals; Apoptosis; Carrier Proteins; Chondrocytes; Diet, High-Fat; Enzyme Activatio | 2016 |
Synovial fluid proteins are required for the induction of interleukin-1β production by monosodium urate crystals.
Topics: Arthritis, Gouty; Case-Control Studies; Cell Line; Enzyme-Linked Immunosorbent Assay; Gout; Humans; | 2016 |
Elevated synovial fluid concentration of adenosine triphosphate in dogs with osteoarthritis or sodium urate-induced synovitis of the stifle.
Topics: Adenosine Triphosphate; Animals; Dog Diseases; Dogs; Female; Male; Osteoarthritis; Stifle; Synovial | 2016 |
A pilot study: sodium urate synovitis as an acute model of inflammatory response using objective and subjective criteria to evaluate arthritic pain in cats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Area Under Curve; Cats; Female; Infl | 2008 |
Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation.
Topics: Aged; Carrier Proteins; Cohort Studies; Female; Humans; Interleukin-1; Interleukin-18; Knee; Male; M | 2011 |
A comparative analysis of serological parameters and oxidative stress in osteoarthritis and rheumatoid arthritis.
Topics: Analysis of Variance; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Chi-Square Distribution | 2012 |
Gout and osteoarthritis: a pathogenetic link?
Topics: Cartilage, Articular; Gout; Humans; Metatarsophalangeal Joint; Osteoarthritis; Uric Acid | 2012 |
Prevalence of calcium pyrophosphate and monosodium urate crystals in synovial fluid of patients with previously diagnosed joint diseases.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Arthritis, Psoriatic; Arthritis, Rheumatoid; | 2013 |
Expression of matrix metalloproteinase-9 (gelatinase B) in gouty arthritis and stimulation of MMP-9 by urate crystals in macrophages.
Topics: Animals; Arthritis, Gouty; Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Enzyme Precu | 2003 |
Effect of ACTH and sodium salicylate on the urinary uric acid: creatinine ratio, and circulating eosinophils in man.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Creatinine; Eosinophils; Gout; Humans | 1953 |
[Hyperuricemia in the entero-arthrotic syndrome and in the etiology of colitis].
Topics: Colitis; Gout; Humans; Hyperuricemia; Joint Diseases; Osteoarthritis; Syndrome; Uric Acid | 1961 |
SERUM URATE IN DEGENERATIVE JOINT DISEASE AND RHEUMATOID ARTHRITIS.
Topics: Arthritis; Arthritis, Rheumatoid; Blood Chemical Analysis; Humans; Osteoarthritis; Uric Acid | 1963 |
THE EPIDEMIOLOGY OF RHEUMATIC DISEASES.
Topics: Arthritis; Arthritis, Rheumatoid; Blood; Colitis; Colitis, Ulcerative; Crohn Disease; Enteritis; Epi | 1964 |
[ULTRASONIC THERAPY IN ARTHROSIS DEFORMANS OF THE KNEE JOINT].
Topics: Calcium; Calcium, Dietary; Humans; Joint Diseases; Knee; Knee Joint; Osteoarthritis; Phosphorus; Ult | 1964 |
PREVALENCE OF CALCIFIED MENISCAL CARTILAGE IN ELDERLY PERSONS.
Topics: Aged; Blood Protein Electrophoresis; Calcinosis; Diagnosis; Geriatrics; Humans; Knee Joint; Latex Fi | 1965 |
Crystal deposition diseases: out of sight, out of mind.
Topics: Calcium Pyrophosphate; Chondrocalcinosis; Chromium Compounds; Crystallization; Disease Progression; | 2005 |
New drugs for crystal deposition diseases.
Topics: Calcinosis; Calcium Compounds; Citrates; Gout; Gout Suppressants; Humans; Joints; Osteoarthritis; Ur | 2006 |
[Red swollen thumb. Soft tissue abscess or joint inflammation].
Topics: Abscess; Aged; Arthritis, Gouty; Diagnosis, Differential; Female; Humans; Osteoarthritis; Soft Tissu | 2007 |
Interpretation of synovial fluid data.
Topics: Arthritis; Arthritis, Rheumatoid; Calcium Pyrophosphate; Cholesterol; Crystallization; Diagnosis, Di | 1980 |
Inflammatory responses to intradermal crystals in healthy volunteers and patients with rheumatic diseases.
Topics: Arthritis, Rheumatoid; Calcium Pyrophosphate; Diphosphates; Gout; Humans; Hydroxyapatites; Intraderm | 1982 |
Musculoskeletal manifestations of Paget's disease of bone.
Topics: Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Back Pain; Female; Gout; Hip Joint; Humans; Knee | 1980 |
The differential diagnosis of septic arthritis in the elderly.
Topics: Aged; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Cellulitis; Diabetic Neuropathies; Di | 1984 |
Urate deposits without gouty arthritis.
Topics: Aged; Arthritis; Arthritis, Rheumatoid; Gout; Humans; Male; Middle Aged; Osteoarthritis; Uric Acid | 1984 |
Nonarticular gout: hyperuricemia and tophus formation without gouty arthritis.
Topics: Aged; Arthritis, Rheumatoid; Ear; Gout; Humans; Kidney; Male; Middle Aged; Osteoarthritis; Synovial | 1983 |
Diflunisal disposition and hypouricemic response in osteoarthritis.
Topics: Aged; Chromatography, High Pressure Liquid; Creatinine; Diflunisal; Dose-Response Relationship, Drug | 1983 |
Epidemiology of Rheumatic disorders in the Pacific with particular emphasis on hyperuricaemia and gout.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child, Preschool; Cross-Sectional Studies; Diabetes | 1981 |
[Hallux rigidus arthrosis and gout].
Topics: Calcium; Gout; Hallux; Humans; Obesity; Osteoarthritis; Uric Acid | 1982 |
Heberden Oration 1981: epidemiology and the arthritides.
Topics: Adolescent; Adult; Age Factors; Aged; Body Weight; Connecticut; Female; Gout; Hand; Humans; Male; Ma | 1982 |
Evaluation of the activity of anti-inflammatory agents by means of skin tests (M.S.U., SK-SD): comparison with clinical results.
Topics: Anti-Inflammatory Agents; Antigens; Arthritis, Rheumatoid; Drug Evaluation; Humans; Immunity, Cellul | 1981 |
Differential diagnosis of main rheumatic diseases in man.
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Glucose; Blood Sedimentation; Blood Urea Nitrogen | 1994 |
Monosodium urate, hydroxyapatite, and calcium pyrophosphate crystals induce tumor necrosis factor-alpha expression in a mononuclear cell line.
Topics: Acetophenones; Animals; Calcium Pyrophosphate; Cell Line; Crystallization; Durapatite; Enzyme Inhibi | 1997 |
Temporomandibular joint osteoarthritis and crystal deposition diseases: a study of crystals in synovial fluid lavages in osteoarthritic temporomandibular joints.
Topics: Adult; Anthraquinones; Arthroscopy; Calcium; Calcium Pyrophosphate; Coloring Agents; Crystallization | 1998 |
[Radiology of the skeleton of the hand. 2. Degenerative joint diseases. Endocrine and metabolic bone diseases].
Topics: Arthritis; Arthritis, Rheumatoid; Bone Diseases; Chondrocalcinosis; Hand; Hemoglobinopathies; Humans | 1999 |
[Purine metabolism enzymes in diagnosis and differential diagnosis of osteoarthritis and gout arthritis].
Topics: 5'-Nucleotidase; Arthritis, Gouty; Biomarkers; Diagnosis, Differential; Female; Humans; Isoenzymes; | 2000 |
Serum uric acid and patterns of radiographic osteoarthritis--the Ulm Osteoarthritis Study.
Topics: Aged; Arthrography; Female; Finger Joint; Germany; Hip Joint; Humans; Male; Middle Aged; Osteoarthri | 2000 |
Analysis of antinociceptive effects of flurbiprofen enantiomers in a rat model of arthritic pain.
Topics: Analgesics; Animals; Area Under Curve; Arthritis; Disease Models, Animal; Dose-Response Relationship | 2000 |
[Spinal complaints of hyperuricemic patients].
Topics: Back Pain; Female; Gout; Headache; Humans; Male; Neurologic Manifestations; Osteoarthritis; Pain; Sp | 1976 |
Stimulation of human purine synthesis de novo by fructose infusion.
Topics: Adolescent; Adult; Creatinine; Erythrocytes; Fructose; Glycine; Gout; Humans; Male; Middle Aged; Ost | 1975 |
[Therapy of hyperlipemia and hyperuricemia with a combination of clofibrate and an extractive mucopolysaccharide complex].
Topics: Adult; Aged; Arthritis, Rheumatoid; Cholesterol; Clofibrate; Drug Therapy, Combination; Female; Glyc | 1975 |
Foibles and fallacies in the diagnosis of arthritis.
Topics: Antibodies, Antinuclear; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Chondrocalcinosis; | 1977 |
Crystal induced arthritis: gout and pseudogout.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents; Apatites; Arthritis; Calcium Hydroxide; Calcium Pyrop | 1978 |
Enzymatic determination of urate, cholesterol and triglycerides in the synovial fluid with the centrifugal fast analyzer.
Topics: Arthritis, Rheumatoid; Centrifugation; Cholesterol; Humans; Hyaluronic Acid; Microchemistry; Osteoar | 1977 |
[Finger polyarthrosis].
Topics: Female; Fingers; Hand Deformities, Acquired; Hot Temperature; Humans; Male; Occupational Diseases; O | 1977 |
New Haven survey of joint diseases. XVII. Relationship between some systemic characteristics and osteoarthrosis in a general population.
Topics: Adult; Age Factors; Aged; Antistreptolysin; Body Height; Body Weight; C-Reactive Protein; Connecticu | 1975 |
Hypertension in relation to musculoskeletal disorders.
Topics: Blood Pressure; Cholesterol; Female; Humans; Hypertension; Intervertebral Disc; Knee Joint; Male; Ne | 1975 |
[Degenerative joint diseases and hypertension (significance of testing hyperuricemia and rheumatoid factor)].
Topics: Adult; Aged; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Osteoarthritis; Rheu | 1976 |
Antibodies against crystals.
Topics: Allopurinol; Animals; Antibody Formation; Arthritis, Rheumatoid; Crystallography; Electrophoresis, P | 1992 |
Gout and main rheumatic diseases in man.
Topics: Adult; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Female; Gout; Humans; Male; Middle Ag | 1991 |
Crystal arthritis: a clinician's view.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, | 1991 |
Evidence for a promoter of urate crystal formation in gouty synovial fluid.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Calcium Pyrophosphate; Crystallization; Femal | 1991 |
Urate-mediated inflammation in nodal osteoarthritis: clinical and roentgenographic correlations.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Gouty; Female; Finger Joint; | 1989 |
Alcohol consumption in arthritic patients: clinical and laboratory studies.
Topics: Alcohol Drinking; Arthritis, Rheumatoid; Erythrocyte Volume; Female; Femur Head Necrosis; gamma-Glut | 1985 |
The role of metabolic factors and blood pressure in the association of obesity with osteoarthritis of the knee.
Topics: Adipose Tissue; Aged; Blood Pressure; Cholesterol; Diabetes Mellitus; Female; Humans; Knee Joint; Ma | 1988 |
Nucleosides and bases in synovial fluid from patients with rheumatoid arthritis and osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Creatinine; Female; Humans; Hypoxanthine; Hyp | 1988 |
Obesity and knee osteoarthritis. The Framingham Study.
Topics: Activities of Daily Living; Adult; Age Factors; Epidemiologic Methods; Female; Humans; Knee Joint; M | 1988 |
[Uric acid levels of the serum of healthy persons and patients with various rheumatic diseases].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Gout; Humans; Male; Middle Aged; Osteoarthri | 1987 |
Frequency of intraarticular monosodium urate (MSU) crystals in asymptomatic hyperuricemic subjects.
Topics: Adult; Aged; Arthritis, Rheumatoid; Crystallization; Female; Humans; Joints; Kidney Failure, Chronic | 1986 |
Prevalence of rheumatoid arthritis, osteoarthritis, chondrocalcinosis and gouty arthritis at age 79.
Topics: Aged; Aging; Arthritis; Arthritis, Rheumatoid; Chondrocalcinosis; Female; Finger Joint; Gout; Hip Jo | 1986 |
The clinical spectrum of gouty arthritis in women.
Topics: Adult; Age Factors; Aged; Arthritis; Diuretics; Female; Gout; Humans; Kidney Diseases; Male; Menopau | 1986 |
[Diagnostic and dispensary care problems of patients with osteoarthrosis deformans].
Topics: Adolescent; Adult; Aged; Ambulatory Care; Arthrography; Chronic Disease; Diagnosis, Differential; Fe | 1985 |
Apatite-type crystal deposition in arthritic cartilage.
Topics: Apatites; Calcium Pyrophosphate; Cartilage, Articular; Electron Probe Microanalysis; Gout; Humans; M | 1985 |
Problems of diagnostic failure in gouty arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Colchicine; Diagnosis, Differential; Diagnostic Errors; Female; | 1972 |
[Uric acid clearance related to the use of an antirheumatic non-steroid drug].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Glomerular Filtration Rate; Go | 1973 |
Some metabolic aspects of diseases of the locomotor system.
Topics: Body Weight; Calcinosis; Calcium Phosphates; Cartilage; Chondrocalcinosis; Female; Gout; Humans; Mal | 1973 |
Phagocytic function of polymorphonuclear leukocytes in rheumatic diseases.
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Humans; Immunoglobulin G; Male; Middle Aged; | 1973 |
Rheumatology.
Topics: Acute Disease; Aged; Analgesics; Arthritis, Rheumatoid; Chronic Disease; Diazepam; Female; Gout; Hum | 1972 |
[Aseptic, primary osteonecrosis of the femur head].
Topics: Alcoholism; Femur Head; Femur Head Necrosis; Gout; Humans; Hyperlipidemias; Ischemia; Obesity; Osteo | 1972 |
Serum uric acid levels following administration of metiazinic acid (Soripal).
Topics: Acetates; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Calcium; Humans; Osteoarthriti | 1973 |
Diseases associated with calcium pyrophosphate dihydrate crystal deposition.
Topics: Adult; Aged; Calcium; Chondrocalcinosis; Creatinine; Diabetes Complications; Female; Gout; Hemochrom | 1974 |
Metabolic and clinical effects of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370).
Topics: Adult; Aged; Anti-Inflammatory Agents; Bilirubin; Blood Cell Count; Diuresis; Female; Hemoglobinomet | 1972 |
[Determination of some biochemical components of intra-articular fluid in the diagnosis of joint diseases].
Topics: Arthritis, Rheumatoid; Glucose; Glucuronidase; Humans; Hydroxybutyrate Dehydrogenase; Joint Diseases | 1971 |
Rheumatism in mining communities in Marion County, West Virginia.
Topics: Adult; Age Factors; Aged; Arthritis; Arthritis, Rheumatoid; Coal Mining; Humans; Latex Fixation Test | 1969 |
Generalized osteoarthrosis in a population sample.
Topics: Age Factors; Aged; Arthritis; England; Female; Humans; Male; Middle Aged; Osteoarthritis; Radiograph | 1969 |
Gouty arthritis of the spine.
Topics: Autopsy; Biopsy; Calculi; Cervical Vertebrae; Colchicine; Female; Gout; Humans; Lumbar Vertebrae; Ma | 1970 |
[Clinical aspects of arthrosis].
Topics: Adult; Age Factors; Aged; Ankle Joint; Brachial Plexus Neuritis; Cervical Vertebrae; Female; Hand; H | 1970 |
[Clinical and metabolic problems in the degenerative joint disease of the diabetic].
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Arthropathy, Neurogenic; Calcaneus; Calcinosis; Dia | 1970 |
Clinical trials of ibuprofen in Milan.
Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Benzyl Compounds; Femal | 1970 |
Ankylosis in osteoarthritis of the finger joints.
Topics: Aged; Ankylosis; Arthritis, Rheumatoid; Blood Sedimentation; Diagnosis, Differential; Female; Finger | 1971 |
Chondrocalcinosis.
Topics: Calcinosis; Calcium Phosphates; Cartilage, Articular; Diagnosis, Differential; Female; Gout; Humans; | 1968 |
Leukocyte-connective tissue cell interaction. II. The specificity, duration, and mechanism of interaction effects.
Topics: Adolescent; Blood Platelets; Culture Techniques; Dactinomycin; Dinitrophenols; Fibroblasts; Freezing | 1969 |
Hyperuricemia induced by high fat diets and starvation.
Topics: Arthritis, Rheumatoid; Blood; Dietary Fats; Fasting; Gout; Humans; Ketone Bodies; Osteoarthritis; Ur | 1965 |
Gout in orthopaedic practice: review of 232 cases.
Topics: Acute Disease; Adolescent; Aged; Bone Diseases; Chlorothiazide; Colchicine; Diagnosis, Differential; | 1963 |