uric acid has been researched along with Optic Neuritis in 3 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have shown that serum uric acid (UA) modulates outcomes of neurological diseases, although little is known about cerebrospinal fluid (CSF) UA levels in neuromyelitis optica spectrum disorders (NMOSDs)." | 7.85 | Elevated cerebrospinal fluid uric acid during relapse of neuromyelitis optica spectrum disorders. ( Hu, X; Li, H; Li, R; Long, Y; Lu, Z; Peng, F; Qiu, W; Shu, Y; Wang, Y; Zhang, L, 2017) |
| "Uric acid, an antioxidant, is reduced in multiple sclerosis (MS)." | 7.72 | Serum uric acid levels in optic neuritis. ( Cherryman, GR; Constantinescu, CS; Gottlob, I; Knapp, CM; McLean, R; Tan, JH, 2004) |
| "Previous studies have shown that serum uric acid (UA) modulates outcomes of neurological diseases, although little is known about cerebrospinal fluid (CSF) UA levels in neuromyelitis optica spectrum disorders (NMOSDs)." | 3.85 | Elevated cerebrospinal fluid uric acid during relapse of neuromyelitis optica spectrum disorders. ( Hu, X; Li, H; Li, R; Long, Y; Lu, Z; Peng, F; Qiu, W; Shu, Y; Wang, Y; Zhang, L, 2017) |
| "Uric acid, an antioxidant, is reduced in multiple sclerosis (MS)." | 3.72 | Serum uric acid levels in optic neuritis. ( Cherryman, GR; Constantinescu, CS; Gottlob, I; Knapp, CM; McLean, R; Tan, JH, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shu, Y | 1 |
| Li, H | 1 |
| Zhang, L | 1 |
| Wang, Y | 1 |
| Long, Y | 1 |
| Li, R | 1 |
| Qiu, W | 1 |
| Lu, Z | 1 |
| Hu, X | 1 |
| Peng, F | 1 |
| Knapp, CM | 1 |
| Constantinescu, CS | 1 |
| Tan, JH | 1 |
| McLean, R | 1 |
| Cherryman, GR | 1 |
| Gottlob, I | 1 |
| Kato, T | 1 |
3 other studies available for uric acid and Optic Neuritis
| Article | Year |
|---|---|
Elevated cerebrospinal fluid uric acid during relapse of neuromyelitis optica spectrum disorders.
Topics: Adolescent; Adult; Aged; Blood-Brain Barrier; Humans; Middle Aged; Multiple Sclerosis; Neuromyelitis | 2017 |
Serum uric acid levels in optic neuritis.
Topics: Adult; Antioxidants; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Scleros | 2004 |
[On uric acid and urea-N in the cerebrospinal fluid in cases of ocular fundus diseases and the influences on several kinds of medicines].
Topics: Ascorbic Acid; Behcet Syndrome; Chorioretinitis; Dexamethasone; Eye Diseases; Female; Humans; Inject | 1970 |