uric acid has been researched along with Nervous System Diseases in 28 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid (UA) is an important natural antioxidant and strong peroxynitrite scavenger, but little is known about central nervous system (CNS) levels of UA in patients with anti-N-methyl-d-aspartate receptor encephalitis (NMDARE)." | 8.31 | Cerebrospinal fluid uric acid levels associated with disease severity in patients with anti-N-methyl-d-aspartate receptor encephalitis. ( Cao, B; Huang, Y; Li, H; Li, Q; Lu, Y; Luo, M; Peng, F; Ruan, H; Shu, Y; Xiong, L, 2023) |
| "Uric acid (UA) was shown to be a strong peroxynitrite scavenger." | 5.35 | Cerebrospinal fluid and serum uric acid levels in patients with multiple sclerosis. ( Drulovic, J; Dujmovic, I; Mostarica Stojkovic, M; Nikolić, A; Obrenovic, R; Pekmezovic, T; Spasic, M, 2009) |
| "A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease." | 4.88 | Cardiovascular and renal effects of hyperuricaemia and gout. ( Leoncini, G; Pontremoli, R; Viazzi, F, 2012) |
| "Uric acid (UA) is an important natural antioxidant and strong peroxynitrite scavenger, but little is known about central nervous system (CNS) levels of UA in patients with anti-N-methyl-d-aspartate receptor encephalitis (NMDARE)." | 4.31 | Cerebrospinal fluid uric acid levels associated with disease severity in patients with anti-N-methyl-d-aspartate receptor encephalitis. ( Cao, B; Huang, Y; Li, H; Li, Q; Lu, Y; Luo, M; Peng, F; Ruan, H; Shu, Y; Xiong, L, 2023) |
| "Patients with neurological disorders have an increased risk of oral and systemic diseases due to compromised oral hygiene." | 1.40 | Enteral nutrition feeding alters antioxidant activity in unstimulated whole saliva composition of patients with neurological disorders. ( Aguiar, SM; Cunha-Correia, AS; Nakamune, AC; Neto, AH; Pereira, AF, 2014) |
| "Uric acid (UA) was shown to be a strong peroxynitrite scavenger." | 1.35 | Cerebrospinal fluid and serum uric acid levels in patients with multiple sclerosis. ( Drulovic, J; Dujmovic, I; Mostarica Stojkovic, M; Nikolić, A; Obrenovic, R; Pekmezovic, T; Spasic, M, 2009) |
| "Metabolic consequences of HGPRT deficiency have been clarified, but the connection with the neurological manifestations is still unknown." | 1.31 | Cytosolic 5'-nucleotidase hyperactivity in erythrocytes of Lesch-Nyhan syndrome patients. ( Allegrini, S; Camici, M; Garcia-Gil, M; Jacomelli, G; Micheli, V; Peruzzi, L; Pesi, R; Tozzi, MG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (64.29) | 18.7374 |
| 1990's | 4 (14.29) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, B | 1 |
| Li, Q | 1 |
| Xiong, L | 1 |
| Ruan, H | 1 |
| Lu, Y | 1 |
| Peng, F | 1 |
| Li, H | 1 |
| Huang, Y | 1 |
| Luo, M | 1 |
| Shu, Y | 1 |
| Cunha-Correia, AS | 1 |
| Neto, AH | 1 |
| Pereira, AF | 1 |
| Aguiar, SM | 1 |
| Nakamune, AC | 1 |
| Dujmovic, I | 1 |
| Pekmezovic, T | 1 |
| Obrenovic, R | 1 |
| Nikolić, A | 1 |
| Spasic, M | 1 |
| Mostarica Stojkovic, M | 1 |
| Drulovic, J | 1 |
| Wei, W | 1 |
| Hemani, G | 1 |
| Hicks, AA | 1 |
| Vitart, V | 1 |
| Cabrera-Cardenas, C | 1 |
| Navarro, P | 1 |
| Huffman, J | 1 |
| Hayward, C | 1 |
| Knott, SA | 1 |
| Rudan, I | 1 |
| Pramstaller, PP | 1 |
| Wild, SH | 1 |
| Wilson, JF | 1 |
| Campbell, H | 1 |
| Dunlop, MG | 1 |
| Hastie, N | 1 |
| Wright, AF | 1 |
| Haley, CS | 1 |
| Viazzi, F | 1 |
| Leoncini, G | 1 |
| Pontremoli, R | 1 |
| CRONE, C | 1 |
| Farstad, M | 1 |
| Haug, JO | 1 |
| Lindbak, H | 1 |
| Skaug, OE | 1 |
| Partington, MW | 1 |
| Hennen, BK | 1 |
| Simmonds, HA | 1 |
| Webster, DR | 1 |
| Wilson, J | 1 |
| Potter, CF | 1 |
| Fairbanks, LD | 1 |
| Hoffman, DJ | 1 |
| Sileo, L | 1 |
| Reiber, H | 1 |
| Ruff, M | 1 |
| Uhr, M | 1 |
| Kuracka, L | 1 |
| Kalnovicová, T | 1 |
| Líska, B | 1 |
| Turcáni, P | 1 |
| Landolt, H | 1 |
| Langemann, H | 1 |
| Alessandri, B | 1 |
| Bonioli, E | 1 |
| DiStefano, A | 1 |
| Palmieri, A | 1 |
| Bertola, A | 1 |
| Bellini, C | 1 |
| Caruso, U | 1 |
| Fantasia, AR | 1 |
| Minniti, G | 1 |
| Dorche, C | 1 |
| Pesi, R | 1 |
| Micheli, V | 1 |
| Jacomelli, G | 1 |
| Peruzzi, L | 1 |
| Camici, M | 1 |
| Garcia-Gil, M | 1 |
| Allegrini, S | 1 |
| Tozzi, MG | 1 |
| Klastersky, J | 1 |
| Láhoda, F | 1 |
| Athen, D | 1 |
| Copti, MC | 1 |
| Lefebvre D'amour, M | 1 |
| Bissoon Doyal, D | 1 |
| Astakhova, LN | 1 |
| Asanova, NK | 1 |
| Armbruster, KF | 1 |
| Ing, TS | 1 |
| Kark, RM | 1 |
| Shinaberger, JH | 1 |
| Miller, JH | 1 |
| Rosenblatt, MG | 1 |
| Gardner, PW | 1 |
| Carpenter, GW | 1 |
| Martin, FE | 1 |
| Young, IJ | 1 |
| Crampton, AR | 1 |
| Merrill, JP | 1 |
| Hampers, CL | 1 |
| Messina, B | 1 |
| Brunelli, E | 1 |
| Munsat, TL | 1 |
| Klinenberg, J | 1 |
| Carell, RE | 1 |
| Menkes, J | 1 |
| Fujimoto, WY | 1 |
| Greene, ML | 1 |
| Seegmiller, JE | 1 |
| Berger, R | 1 |
| Broyer, M | 1 |
3 reviews available for uric acid and Nervous System Diseases
| Article | Year |
|---|---|
Cardiovascular and renal effects of hyperuricaemia and gout.
Topics: Biomarkers; Cardiovascular Diseases; Diabetes Complications; Disease Progression; Evidence-Based Med | 2012 |
[Medical complications of chemotherapy].
Topics: Antineoplastic Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Gastrointestina | 1975 |
Uremia (first of two parts). Uremia. I.
Topics: Acidosis; Carbohydrate Metabolism; Eye Diseases; Gastrointestinal Diseases; Glomerular Filtration Ra | 1970 |
25 other studies available for uric acid and Nervous System Diseases
| Article | Year |
|---|---|
Cerebrospinal fluid uric acid levels associated with disease severity in patients with anti-N-methyl-d-aspartate receptor encephalitis.
Topics: Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Blood-Brain Barrier; Humans; Nervous System Disease | 2023 |
Enteral nutrition feeding alters antioxidant activity in unstimulated whole saliva composition of patients with neurological disorders.
Topics: Adolescent; Adult; Antioxidants; Case-Control Studies; Deglutition Disorders; Enteral Nutrition; Fem | 2014 |
Cerebrospinal fluid and serum uric acid levels in patients with multiple sclerosis.
Topics: Adult; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Ner | 2009 |
Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.
Topics: Croatia; Epistasis, Genetic; ERRalpha Estrogen-Related Receptor; Genome-Wide Association Study; Gluc | 2011 |
Uric acid in the cerebrospinal fluid; the relative concentration in meningitis and other neurological disorders.
Topics: Humans; Meningitis; Nervous System Diseases; Uric Acid | 1957 |
URIC ACID IN THE CEREBROSPINAL FLUID IN CEREBRAL ATROPHY.
Topics: Atrophy; Blood Chemical Analysis; Brain Diseases; Cerebrospinal Fluid; Humans; Nervous System Diseas | 1965 |
The Lesch-Nyhan syndrome: self-destructive biting, mental retardation, neurological disorder and hyperuricaemia.
Topics: Ascorbic Acid; Body Weight; Child, Preschool; Diet Therapy; Humans; Intellectual Disability; Male; M | 1967 |
Evidence of a new syndrome involving hereditary uric acid over-production, neurological complications and deafness.
Topics: Clinical Laboratory Techniques; Deafness; Erythrocytes; Female; Humans; Infant, Newborn; Kinetics; M | 1984 |
Neurotoxic and teratogenic effects of an organophosphorus insecticide (phenyl phosphonothioic acid-O-ethyl-O-[4-nitrophenyl] ester) on mallard development.
Topics: Animals; Body Weight; Brain; Brain Chemistry; Ducks; Enzymes; Hematocrit; Hemoglobins; Insecticides; | 1984 |
Ascorbate concentration in human cerebrospinal fluid (CSF) and serum. Intrathecal accumulation and CSF flow rate.
Topics: Ascorbic Acid; Capillary Permeability; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Hu | 1993 |
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.
Topics: Adult; Brain Ischemia; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hyp | 1996 |
A concept for the introduction of cerebral microdialysis in neurointensive care.
Topics: Animals; Ascorbic Acid; Bicarbonates; Brain; Carbon Dioxide; Craniocerebral Trauma; Critical Care; C | 1996 |
Combined deficiency of xanthine oxidase and sulphite oxidase due to a deficiency of molybdenum cofactor.
Topics: Coenzymes; Female; Fibroblasts; Humans; Hypoxanthine; Infant; Metabolism, Inborn Errors; Metalloprot | 1996 |
Cytosolic 5'-nucleotidase hyperactivity in erythrocytes of Lesch-Nyhan syndrome patients.
Topics: 5'-Nucleotidase; Adolescent; Adult; Aminoimidazole Carboxamide; Animals; Apoptosis; Autistic Disorde | 2000 |
Typing of uric acid level in cerebrospinal fluid in neurological and psychiatric diseases.
Topics: Humans; Nervous System Diseases; Psychotic Disorders; Uric Acid | 1977 |
[Metabolism and adverse effects of ethanol].
Topics: Acidosis; Alcoholic Intoxication; Alcoholism; Animals; Cholesterol; Deficiency Diseases; Dose-Respon | 1977 |
[Borderline neuropsychiatric disorders in purine metabolism disorders in children].
Topics: Adolescent; Arthritis; Brain Diseases; Child; Child, Preschool; Disease Susceptibility; Female; Huma | 1985 |
Medical Grand Rounds from the University of Alabama Medical Center. Lead poisoning.
Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Anemia, Macrocytic; Brain Diseases; Diagnosi | 1972 |
[Dialysis-free treatment of chronic kidney insufficiency].
Topics: Acidosis, Renal Tubular; Anemia; Anuria; Diet Therapy; Dietary Proteins; Drinking; Heart Diseases; H | 1974 |
Clinical studies of 'low flow' dialysis with membranes highly permeable to middle weight molecules.
Topics: Acetates; Blood Flow Velocity; Blood Urea Nitrogen; Cellulose; Creatinine; Hematocrit; Humans; Male; | 1972 |
Cerebrospinal fluid uric acid levels in cerebral atrophy occurring in psychiatric and neurologic patients.
Topics: Adult; Age Factors; Aged; Alcoholism; Atrophy; Brain Diseases; Female; Hospitalization; Humans; Male | 1974 |
[Basic concepts of physics for the interpretation of the curative effect of radioactive mineral waters].
Topics: Female; Genital Diseases, Female; Gout; Humans; Hypertension; Infertility, Female; Joint Diseases; M | 1969 |
Defects in purine metabolism and neurologic disease.
Topics: Brain; Cerebellum; Child; Glucosyltransferases; Gout; Hemorrhage; Humans; Male; Necrosis; Nervous Sy | 1968 |
X-linked uric aciduria with neurological disease and self-mutilation: diagnostic test for the enzyme defect.
Topics: Clinical Enzyme Tests; Glucosyltransferases; Humans; Methods; Nervous System Diseases; Purine-Pyrimi | 1968 |
[Congenital hyperuricemia with neurologic disorders].
Topics: Allopurinol; Guanine; Humans; Hypoxanthines; Intellectual Disability; Kidney Diseases; Metabolism, I | 1968 |