Page last updated: 2024-10-20

uric acid and Nephrotic Syndrome

uric acid has been researched along with Nephrotic Syndrome in 29 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of oral mizoribine (MZB) pulse therapy given twice a week for frequently relapsing steroid-dependent nephrotic syndrome (FR-SDNS)."9.13Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome. ( Fujieda, M; Hayashi, A; Ishihara, M; Morita, T; Ohta, T; Sakano, T; Utsunomiya, Y; Wakiguchi, H, 2008)
"Uric acid transport was not affected in children treated with Cyclosporine (CyA) for nephrotic syndrome (NEPH group) compared to the CON group."5.28Cyclosporine inhibits renal uric acid transport in renal transplants not in children treated for nephrotic syndrome. ( Brandis, M; Kramer, M; Leititis, JU; Steidel, K; Zimmerhackl, LB, 1990)
"To evaluate the efficacy of oral mizoribine (MZB) pulse therapy given twice a week for frequently relapsing steroid-dependent nephrotic syndrome (FR-SDNS)."5.13Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome. ( Fujieda, M; Hayashi, A; Ishihara, M; Morita, T; Ohta, T; Sakano, T; Utsunomiya, Y; Wakiguchi, H, 2008)
" Compared to those in normal serum uric acid group, the incidence of hypertension (33%, 16/48), serum triglyceride [2."3.80[Relationship between hyperuricemia and primary nephrotic syndrome in children]. ( Li, Q; Wang, F; Xiao, H; Yao, Y; Zhong, X, 2014)
"In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death."2.36Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980)
"Hyperlipidemia associated with nephrotic syndrome may play a role in the worsening of renal function."1.34Protective role of sulphated polysaccharides in abating the hyperlipidemic nephropathy provoked by cyclosporine A. ( Amudha, G; Josephine, A; Preetha, SP; Varalakshmi, P; Veena, CK, 2007)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199018 (62.07)18.7374
1990's2 (6.90)18.2507
2000's3 (10.34)29.6817
2010's2 (6.90)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Lu, H1
Xiao, L1
Song, M1
Liu, X1
Wang, F3
Li, H1
Jia, J1
Yan, T1
Liu, Y1
Lin, S1
Ji, X1
Zhang, J1
Li, Y2
Hu, L1
Han, X1
Xiao, Y1
Tang, Y1
Zheng, X1
Anwar, M1
Qin, W1
Hejazian, SM1
Rahbar Saadat, Y1
Bahmanpour, Z1
Hosseiniyan Khatibi, SM1
Ardalan, M1
Zununi Vahed, S1
Xiao, H1
Li, Q1
Yao, Y1
Zhong, X1
PASTERNACK, A1
KUHLBAECK, B1
TALLGREN, LG1
Josephine, A1
Veena, CK1
Amudha, G1
Preetha, SP1
Varalakshmi, P1
He, L1
Rong, X1
Jiang, JM1
Liu, PQ1
Fujieda, M1
Ishihara, M1
Morita, T1
Hayashi, A1
Utsunomiya, Y1
Ohta, T1
Sakano, T1
Wakiguchi, H1
Derr, RF1
Alexander, CS2
Nagasawa, HT2
Swingle, KF1
Guyon, B1
Ory, JP1
Delacour, JL1
Wagschal, G1
Daoudal, P1
Pascal, RR1
Berlyne, GM1
Sutton, J1
Brown, C1
Caruso, C1
Friedman, EA1
Fer, MF1
McKinney, TD1
Richardson, RL1
Hande, KR1
Oldham, RK1
Greco, FA1
Morgan, A1
Birch, H1
Lee, HA1
Suki, WN1
Panasiuk, NN1
Mukhin, NA1
Varshavskiĭ, VA1
Maksimov, NA1
Nikolaev, AIu1
Poliantseva, LR1
Balkarov, IM1
Golov, KG1
Antonov, MV1
Aleksandrovskaia, TN1
Steidel, K1
Brandis, M1
Kramer, M1
Leititis, JU1
Zimmerhackl, LB1
Puschett, JB1
Wegienka, LC1
Simpson, RG1
Karam, JH1
Forsham, PH1
Buckalew, VM1
Someren, A1
Lagrue, G1
Masbernard, A1
Giudicelli, C1
Hirbec, G1
Leiter, L1
Anderton, JL1
Kincaid-Smith, P1
Kiely, JM1
Wagoner, RD1
Holley, KE1
Ströder, J1
Mingers, A1
Castello, D1
Rosmino, GC1
Baroncelli, PG1
Ghidella, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness and Safety of Danshen Injection for Acute Kidney Injury in Primary Nephrotic Syndrome[NCT06071533]441 participants (Actual)Observational2012-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for uric acid and Nephrotic Syndrome

ArticleYear
[Renal failure caused by non-steroid anti-inflammatory agents].
    La Revue de medecine interne, 1983, Volume: 4, Issue:2

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Drug Interactions; Glomerulonephritis; Humans; Hy

1983
Renal manifestations of extrarenal neoplasms.
    Human pathology, 1980, Volume: 11, Issue:1

    Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm

1980
Cancer and the kidney: complications of neoplasms.
    The American journal of medicine, 1981, Volume: 71, Issue:4

    Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypercalcemia; I

1981
Renal involvement in leukemia and lymphoma.
    Perspectives in nephrology and hypertension, 1976, Volume: 3

    Topics: Amyloidosis; Blood Vessels; Diabetes Insipidus; Humans; Hypercalcemia; Hyponatremia; Kidney; Kidney

1976
Renal manifestations of sickle cell disease.
    Archives of internal medicine, 1974, Volume: 133, Issue:4

    Topics: Acid-Base Equilibrium; Age Factors; Anemia, Sickle Cell; Capillaries; Dilatation; Erythrocytes, Abno

1974
Combinations of diuretics in the treatment of edema.
    American heart journal, 1970, Volume: 80, Issue:3

    Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu

1970
Diuretics. II. Clinical considerations.
    Drugs, 1971, Volume: 1, Issue:2

    Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I

1971

Trials

2 trials available for uric acid and Nephrotic Syndrome

ArticleYear
Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome.
    Clinical nephrology, 2008, Volume: 69, Issue:3

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Fe

2008
Use of a new anti-inflammatory agent, bucloxic acid, in the treatment of chronic glomerular nephropathies.
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9A SUPPL

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Blood Urea Nitrogen; Chronic Disease; Clinical Trials a

1974

Other Studies

20 other studies available for uric acid and Nephrotic Syndrome

ArticleYear
Acute kidney injury in patients with primary nephrotic syndrome: influencing factors and coping strategies.
    BMC nephrology, 2022, 03-05, Volume: 23, Issue:1

    Topics: Acute Kidney Injury; Adaptation, Psychological; Albumins; Creatinine; Female; Humans; Male; Nephroti

2022
The difference between patients with nephrotic syndrome and nephrotic-range proteinuria in IgA nephropathy: a propensity score matched cohort study.
    BMC nephrology, 2022, 04-29, Volume: 23, Issue:1

    Topics: Adult; Cohort Studies; Creatinine; Female; Glomerulonephritis, IGA; Humans; Male; Nephrotic Syndrome

2022
Influencing Factors of Quality of Life and Prediction Model Building in Patients with Primary Nephrotic Syndrome: A Single-Centre Retrospective Study.
    Archivos espanoles de urologia, 2023, Volume: 76, Issue:4

    Topics: Clinical Decision Rules; Humans; Nephrotic Syndrome; Quality of Life; Retrospective Studies; Uric Ac

2023
Clinical and pathological features of immunoglobulin A nephropathy patients with nephrotic syndrome.
    Clinical and experimental medicine, 2019, Volume: 19, Issue:4

    Topics: Adult; China; Creatine; Disease Progression; Female; Glomerular Filtration Rate; Glomerulonephritis,

2019
Dicer and Drosha expression in patients with nephrotic syndrome.
    BioFactors (Oxford, England), 2020, Volume: 46, Issue:4

    Topics: Adult; Case-Control Studies; Creatinine; DEAD-box RNA Helicases; Female; Gene Expression Regulation;

2020
[Relationship between hyperuricemia and primary nephrotic syndrome in children].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2014, Volume: 52, Issue:11

    Topics: Child; Creatinine; Humans; Hypertension; Hyperuricemia; Nephrotic Syndrome; Retrospective Studies; U

2014
SERUM INDICAN IN RENAL DISEASE.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Blood; Creatine; Creatinine; Glomerulonephritis; Indican; Kidney Diseases; Nephrotic Syndrome; Urea;

1964
Protective role of sulphated polysaccharides in abating the hyperlipidemic nephropathy provoked by cyclosporine A.
    Archives of toxicology, 2007, Volume: 81, Issue:5

    Topics: Animals; Cholesterol, LDL; Cholesterol, VLDL; Creatinine; Cyclosporine; Hyperlipidemias; Hypolipidem

2007
Amelioration of anti-cancer agent adriamycin-induced nephrotic syndrome in rats by Wulingsan (Gorei-San), a blended traditional Chinese herbal medicine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:5

    Topics: Angiotensin II; Animals; Antibiotics, Antineoplastic; Blotting, Western; Doxorubicin; Glyceraldehyde

2008
Metabolism of puromycin aminonucleoside in the normal, "pre-nephrotic," and nephrotic rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 125, Issue:1

    Topics: Animals; Carbon Dioxide; Carbon Isotopes; Feces; Hydantoins; Hypoxanthines; Ion Exchange; Male; Neph

1967
Metabolism of aminonucleoside-8-14C in the rat and guinea pig.
    Biochemical pharmacology, 1967, Volume: 16, Issue:11

    Topics: Adenine; Adrenal Glands; Allantoin; Amines; Animals; Biliary Tract; Carbon Dioxide; Carbon Isotopes;

1967
Renal handling of urate during water immersion in the nephrotic syndrome.
    Mineral and electrolyte metabolism, 1984, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Baths; Female; Humans; Hydrostatic Pressure; Immersion; Kidney; Kidney Tubules, P

1984
The use of tienilic acid in nephrotic syndrome: a clinical study.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adolescent; Adult; Aged; Cholesterol; Female; Furosemide; Glycolates; Humans; Male; Middle Aged; Nep

1979
[The clinico-morphological characteristics of psoriatic nephropathy].
    Terapevticheskii arkhiv, 1990, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Psoriatic; Chronic Disease; Female; Glomerulonephri

1990
Cyclosporine inhibits renal uric acid transport in renal transplants not in children treated for nephrotic syndrome.
    Renal failure, 1990, Volume: 12, Issue:3

    Topics: Adolescent; Analysis of Variance; Biological Transport; Child; Child, Preschool; Cyclosporins; Glome

1990
Diuretic therapy update.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Diet, Sodium-Restricted; Diuretics; Ear Diseases; Heart Fa

1985
Clinical experience with diazoxide.
    Annals of the New York Academy of Sciences, 1968, Apr-11, Volume: 150, Issue:2

    Topics: Adenoma, Islet Cell; Adrenal Glands; Adult; Aged; Benzothiadiazines; Blood Glucose; Diabetes Mellitu

1968
Renal complications of lymphoma.
    Annals of internal medicine, 1969, Volume: 71, Issue:6

    Topics: Adult; Aged; Amyloidosis; Female; Humans; Hydronephrosis; Hypercalcemia; Hypertension, Renal; Kidney

1969
[Modification of certain parameters of blood coagulation by peritoneal dialysis].
    Monatsschrift fur Kinderheilkunde, 1969, Volume: 117, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Coagulation; Blood Coagulation Factors; Calcium; Creatinine; Female;

1969
[Uricemia in the pediatric age. II. In kidney diseases].
    Minerva pediatrica, 1968, Jan-14, Volume: 20, Issue:2

    Topics: Child; Child, Preschool; Female; Glomerulonephritis; Humans; Infant; Infant, Newborn; Male; Nephroti

1968