Page last updated: 2024-10-20

uric acid and Nephrosis

uric acid has been researched along with Nephrosis in 11 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

Research Excerpts

ExcerptRelevanceReference
" Puromycin aminonucleoside nephrosis (PAN) is a rat model of minimal change nephrotic syndrome."7.85Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats. ( Fujigaki, Y; Hosoyamada, M; Kawamorita, Y; Kumagai, T; Nakagawa, T; Shibata, S; Shiraishi, T; Tamura, Y; Uchida, S, 2017)
"To observe the ameliorative effect of Zishen Decoction (ZSD) on chronic uric acid nephrosis (CUAN)."7.70[Clinical study on Zishen Decoction in chronic uric acid nephrosis]. ( Ni, Q; Shi, Z; Zheng, Q, 1998)
" The hypothesis was tested that the renal xanthine oxidase system provides a source of oxygen free radicals in puromycin aminonucleoside and adriamycin experimental nephrosis by generating uric acid from hypoxanthine and xanthine."7.68Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis. ( Acerbo, S; Allegrini, S; Bertelli, R; Cercignani, G; D'Allegri, F; Ghiggeri, G; Ginevri, F; Gusmano, R; Oleggini, R; Perfumo, F, 1990)
" Puromycin aminonucleoside nephrosis (PAN) is a rat model of minimal change nephrotic syndrome."3.85Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats. ( Fujigaki, Y; Hosoyamada, M; Kawamorita, Y; Kumagai, T; Nakagawa, T; Shibata, S; Shiraishi, T; Tamura, Y; Uchida, S, 2017)
"To observe the ameliorative effect of Zishen Decoction (ZSD) on chronic uric acid nephrosis (CUAN)."3.70[Clinical study on Zishen Decoction in chronic uric acid nephrosis]. ( Ni, Q; Shi, Z; Zheng, Q, 1998)
" The hypothesis was tested that the renal xanthine oxidase system provides a source of oxygen free radicals in puromycin aminonucleoside and adriamycin experimental nephrosis by generating uric acid from hypoxanthine and xanthine."3.68Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis. ( Acerbo, S; Allegrini, S; Bertelli, R; Cercignani, G; D'Allegri, F; Ghiggeri, G; Ginevri, F; Gusmano, R; Oleggini, R; Perfumo, F, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawamorita, Y1
Shiraishi, T1
Tamura, Y1
Kumagai, T1
Shibata, S1
Fujigaki, Y1
Hosoyamada, M1
Nakagawa, T1
Uchida, S1
Jin, X1
Lok, E1
Caldwell, D1
Mueller, R1
Kapal, K1
Liston, V1
Kubow, S1
Chan, HM1
Mehta, R1
BROPHY, EM1
ASHWORTH, CT1
ARIAS, M1
REYNOLDS, J1
RIESELBACH, RE1
BENTZEL, CJ1
COTLOVE, E1
FREI, E1
FREIREICH, EJ1
Futrakul, P1
Yenrudi, S1
Futrakul, N1
Sensirivatana, R1
Kingwatanakul, P1
Jungthirapanich, J1
Cherdkiadtikul, T1
Laohapaibul, A1
Watana, D1
Singkhwa, V1
Futrakul, S1
Pongsin, P1
Ni, Q1
Shi, Z1
Zheng, Q1
Ginevri, F1
Gusmano, R1
Oleggini, R1
Acerbo, S1
Bertelli, R1
Perfumo, F1
Cercignani, G1
Allegrini, S1
D'Allegri, F1
Ghiggeri, G1
Bhambal, SA1
Sharma, KS1
Bhambal, S1
Richter, R1
Hermanny, G1
Hofer, E1
Stobbe, H1
Doliopoulos, T1
Liaskou, F1
Marousis, S1
Heath, BC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of IL-2 for Pediatric, Multi Drug Resistant, Idiopathic Nephrotic Syndrome[NCT02455908]Phase 1/Phase 25 participants (Actual)Interventional2012-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for uric acid and Nephrosis

ArticleYear
Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats.
    Physiological reports, 2017, Volume: 5, Issue:15

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cell Line; Deoxyguanosine; Enzyme Inhibitors; Ki

2017
Dietary fats altered nephrotoxicity profile of methylmercury in rats.
    Journal of applied toxicology : JAT, 2009, Volume: 29, Issue:2

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Calcium; Cholesterol; Creatinine; Diet; Dietary Fats; Doc

2009
ACUTE SYPHILITIC NEPHROSIS IN PREGNANCY.
    Obstetrics and gynecology, 1964, Volume: 24

    Topics: Blood Protein Electrophoresis; Bone Diseases; Communicable Diseases; Electrons; Female; Fluorescent

1964
URIC ACID EXCRETION AND RENAL FUNCTION IN THE ACUTE HYPERURICEMIA OF LEUKEMIA. PATHOGENESIS AND THERAPY OF URIC ACID NEPHROPATHY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Acetazolamide; Bicarbonates; Blood; Carbon Isotopes; Drug Therapy; Fluids and Secretions; Hippurates

1964
Tubular function and tubulointerstitial disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:5

    Topics: Adolescent; Biological Transport; Calcium; Child; Female; Glomerular Mesangium; Glomerulonephritis;

1999
[Clinical study on Zishen Decoction in chronic uric acid nephrosis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998, Volume: 18, Issue:5

    Topics: Adult; Aged; Chronic Disease; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Nephrosis; Q

1998
Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:3

    Topics: Allantoin; Animals; Doxorubicin; Hypoxanthines; Kidney; Male; Nephrosis; Proteinuria; Purines; Purom

1990
Relationship between short duration and 24-hour urinary excretion pattern of some nitrogenous compounds.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Creatine; Creatinine; Hepatitis A; Humans; Liver C

1972
[Secondary hyperuricemia in hemoblastosis].
    Das Deutsche Gesundheitswesen, 1971, Nov-04, Volume: 26, Issue:45

    Topics: Blood Cell Count; Humans; Leukemia; Myeloproliferative Disorders; Nephrosis; Polycythemia Vera; Prim

1971
Comparison of the action of two new oral diuretics, the 4-chloro-N-methyl-3-(methylsulfamoly) benzamide and 4-chloro-3-sulfamylbenzoic acid 2,2-dimethylhydrazide (a study on 102 patients).
    Acta cardiologica, 1968, Volume: 23, Issue:5

    Topics: Adult; Aged; Arteries; Blood Glucose; Blood Pressure; Body Weight; Diuretics; Edema; Heart Failure;

1968
Chemical pathology of nephrosis induced by an infectious bronchitis virus.
    Avian diseases, 1970, Volume: 14, Issue:1

    Topics: Animals; Blood Glucose; Calcium; Chickens; Food; Hematocrit; Hydrogen-Ion Concentration; Muscles; Ne

1970