Page last updated: 2024-10-20

uric acid and Nephrocalcinosis

uric acid has been researched along with Nephrocalcinosis in 27 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Nephrocalcinosis: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to test the effect of L: -arginine methyl ester (L-Arg) on indices of free radical involvement in a rat model of experimental nephrocalcinosis."7.73The effect of L-arginine methyl ester on indices of free radical involvement in a rat model of experimental nephrocalcinosis. ( Buyukbayram, H; Ozturk, H; Yagmur, Y, 2006)
" Hyperuricemia leads to hyperuricuria and uric acid nephrolithiasis."3.74Rare variant of Lesch-Nyhan syndrome without self-mutilation or nephrolithiasis. ( Kersnik Levart, T, 2007)
"The aim of this study was to test the effect of L: -arginine methyl ester (L-Arg) on indices of free radical involvement in a rat model of experimental nephrocalcinosis."3.73The effect of L-arginine methyl ester on indices of free radical involvement in a rat model of experimental nephrocalcinosis. ( Buyukbayram, H; Ozturk, H; Yagmur, Y, 2006)
"In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death."2.36Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980)
"Nephrocalcinosis was described in preterm infants by several authors who tried to determine its association with hypercalciuria and furosemide therapy."1.29Nephrocalcinosis and prematurity: importance of urate and oxalate excretion. ( Bekri, S; Bérard, E; Boutté, P; Coussement, A; Dageville, C; Mariani, R, 1995)
"Moreover, a total 14 cases of pseudo-Bartter's syndrome reported in Japanese literature is reviewed."1.26Pseudo-Bartter's syndrome due to furosemide abuse: report of a case and an analytical review of Japanese literature. ( Isozaki, S; Nakayama, M; Sato, T; Tajiri, J; Uchino, K, 1981)
"Nine cases of chronic lymphocytic leukemia (CLL) served as controls."1.25Pathoanatomical features of the kidney in myelomonocytic and chronic lymphocytic leukemia. ( Schwarze, EW, 1975)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199013 (48.15)18.7374
1990's6 (22.22)18.2507
2000's5 (18.52)29.6817
2010's3 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cunha, NB1
Kawano, PR1
Padovani, CR1
Lima, Fde O1
Bernardes, S1
Magalhães, ES1
Amaro, CR1
Amaro, JL1
Jurecka, A1
Stiburkova, B1
Krijt, J1
Gradowska, W1
Tylki-Szymanska, A1
Giapros, V1
Tsoni, C1
Challa, A1
Cholevas, V1
Argyropoulou, M1
Papadopoulou, F1
Siomou, E1
Drougia, A1
Andronikou, S1
Sikora, P1
Roth, B1
Kribs, A1
Michalk, DV1
Hesse, A1
Hoppe, B1
SCOTT, JT1
DIXON, AS1
BYWATERS, EG1
Ozturk, H2
Yagmur, Y1
Buyukbayram, H1
Kersnik Levart, T1
Sasaki, S1
Pascal, RR1
Brown, DC1
Tajiri, J1
Nakayama, M1
Sato, T1
Isozaki, S1
Uchino, K1
Bérard, E1
Dageville, C1
Bekri, S1
Boutté, P1
Coussement, A1
Mariani, R1
Marangella, M1
Vitale, C1
Petrarulo, M1
Rovera, L1
Dutto, F1
Kikuchi, T1
Matsuzaki, H1
Sato, S1
Kajita, Y1
Chiba, H1
Tsuchiya, H1
Masuyama, R1
Uehara, M1
Suzuki, K1
Goto, S1
Nakamura, Y1
Ono, H1
Frohlich, ED1
Schwille, PO1
Schmiedl, A1
Manoharan, M1
Wipplinger, J1
Zefirova, GS1
Zakutniaia, VN1
Bufakhreddin, S1
Plevako, VA1
Burmistrova, NL1
Malek, RS2
Heidelmann, G1
Kim, KM1
Schwarze, EW1
Sakly, R1
Hdhili, A1
Zarrouk, K1
Mbazaa, A1
McCarty, DJ1
Hunt, RD1
Garcia, FG1
Walsh, RJ1
Boyce, WH1
Lavan, JN1
Neale, FC1
Posen, S1
Attard, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00249951]Phase 380 participants (Actual)Interventional2005-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for uric acid and Nephrocalcinosis

ArticleYear
[Hereditary kidney tubular diseases].
    Nihon Jinzo Gakkai shi, 2007, Volume: Suppl 50th Ann

    Topics: Acidosis, Renal Tubular; Animals; Aquaporins; Chloride Channels; Chloride-Bicarbonate Antiporters; D

2007
Renal manifestations of extrarenal neoplasms.
    Human pathology, 1980, Volume: 11, Issue:1

    Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm

1980
Kidney stones: current issues in diagnosis and therapy.
    Postgraduate medicine, 1982, Volume: 72, Issue:6

    Topics: Allopurinol; Benzothiadiazines; Calcium Oxalate; Diuretics; Humans; Hydrogen-Ion Concentration; Hype

1982
Is there a role for uric acid in an animal model of calcium phosphate nephrocalcinosis and calcium phosphate crystallization in urine of patients with idiopathic calcium urolithiasis? An orientational study.
    Journal of endourology, 1999, Volume: 13, Issue:9

    Topics: Animals; Calcium; Calcium Phosphates; Crystallization; Disease Models, Animal; Humans; Nephrocalcino

1999
Renal lithiasis: a practical approach.
    The Journal of urology, 1977, Volume: 118, Issue:6

    Topics: Acidosis, Renal Tubular; Adult; Child, Preschool; Cystinuria; Female; Humans; Hypercalcemia; Intesti

1977

Trials

1 trial available for uric acid and Nephrocalcinosis

ArticleYear
Effects of mineral composition of drinking water on risk for stone formation and bone metabolism in idiopathic calcium nephrolithiasis.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3

    Topics: Adult; Bicarbonates; Bone and Bones; Calcitriol; Calcium; Calcium Oxalate; Calcium Phosphates; Colla

1996

Other Studies

21 other studies available for uric acid and Nephrocalcinosis

ArticleYear
Nephrocalcinosis induced by hyperoxaluria in rats.
    Acta cirurgica brasileira, 2013, Volume: 28, Issue:7

    Topics: Animals; Calcium; Citric Acid; Hyperoxaluria; Kidney; Male; Nephrocalcinosis; Oxalates; Random Alloc

2013
Xanthine dehydrogenase deficiency with novel sequence variations presenting as rheumatoid arthritis in a 78-year-old patient.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Aged; Allopurinol; Arthritis, Rheumatoid; Biomarkers; Chromatography, High Pressure Liquid; DNA Muta

2010
Renal function and kidney length in preterm infants with nephrocalcinosis: a longitudinal study.
    Pediatric nephrology (Berlin, Germany), 2011, Volume: 26, Issue:10

    Topics: Creatinine; Electrolytes; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Prematur

2011
Hypocitraturia is one of the major risk factors for nephrocalcinosis in very low birth weight (VLBW) infants.
    Kidney international, 2003, Volume: 63, Issue:6

    Topics: Calcium; Citric Acid; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature;

2003
ASSOCIATION OF HYPERURICAEMIA AND GOUT WITH HYPERPARATHYROIDISM.
    British medical journal, 1964, Apr-25, Volume: 1, Issue:5390

    Topics: Adenoma; Blood Chemical Analysis; Diagnosis; Gout; Humans; Hyperparathyroidism; Hyperuricemia; Nephr

1964
The effect of L-arginine methyl ester on indices of free radical involvement in a rat model of experimental nephrocalcinosis.
    Urological research, 2006, Volume: 34, Issue:5

    Topics: Animals; Arginine; Blood Urea Nitrogen; Calcium Oxalate; Catalase; Creatinine; Crystallization; Dise

2006
Rare variant of Lesch-Nyhan syndrome without self-mutilation or nephrolithiasis.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:11

    Topics: Cerebral Palsy; Child; Diagnosis, Differential; Humans; Kidney; Lesch-Nyhan Syndrome; Male; Nephroca

2007
Pseudo-Bartter's syndrome due to furosemide abuse: report of a case and an analytical review of Japanese literature.
    Japanese journal of medicine, 1981, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Bartter Syndrome; Calcium; Diagnosis, Differential; Female; Furosemide; Hum

1981
Nephrocalcinosis and prematurity: importance of urate and oxalate excretion.
    Nephron, 1995, Volume: 69, Issue:3

    Topics: Glycosuria; Humans; Hypercalcemia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases;

1995
Diminished kidney function and nephrocalcinosis in rats fed a magnesium-deficient diet.
    Journal of nutritional science and vitaminology, 1998, Volume: 44, Issue:4

    Topics: Acetylglucosaminidase; Animal Feed; Animals; Calcium; Creatinine; Kidney; Magnesium Deficiency; Male

1998
Differential effects of T- and L-type calcium antagonists on glomerular dynamics in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Calcium Chan

1999
[Bartter's syndrome with hyperuricemia and nephrocalcinosis].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:11

    Topics: Adult; Bartter Syndrome; Diagnosis, Differential; Disease Progression; Humans; Kidney Failure, Chron

2000
[Early diagnosis of gout].
    Zeitschrift fur arztliche Fortbildung, 1979, Jul-15, Volume: 73, Issue:13-14

    Topics: Adult; Allopurinol; Efficiency; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Nephrocalc

1979
X-ray analysis of pathological calcifications including urinary stones.
    Scanning electron microscopy, 1979, Issue:2

    Topics: Aorta; Calcinosis; Calcium; Crystallization; Electron Probe Microanalysis; Microscopy, Electron; Nep

1979
Pathoanatomical features of the kidney in myelomonocytic and chronic lymphocytic leukemia.
    Virchows Archiv. A, Pathological anatomy and histology, 1975, Oct-30, Volume: 368, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Edema; Female; Humans; Kidney; Kidney Glomerulus; Kidney Tubules;

1975
[The effect of the administration of a high dose of vitamin D3 on calculus formation in rats].
    Annales d'urologie, 1990, Volume: 24, Issue:7

    Topics: Animals; Calcium; Cholecalciferol; Creatinine; Kidney; Kidney Calculi; Male; Nephrocalcinosis; Oxala

1990
Intractable gouty arthritis.
    Hospital practice (Office ed.), 1987, Jun-15, Volume: 22, Issue:6

    Topics: Allopurinol; Arthritis; Colchicine; Duodenal Ulcer; Gout; Humans; Hypertension; Indomethacin; Male;

1987
A comparison of the toxicity of ergocalciferol and cholecalciferol in rhesus monkeys (Macaca mulatta).
    The Journal of nutrition, 1972, Volume: 102, Issue:8

    Topics: Administration, Oral; Animals; Bone Diseases; Cholecalciferol; Diet; Ergocalciferols; Gout; Haplorhi

1972
Intranephronic calculosis: its significance and relationship to matrix in nephrolithiasis.
    The Journal of urology, 1973, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Aged; Biopsy; Calcium; Child; Child, Preschool; Colonic Neoplasms; Cystine; Epith

1973
Urinary calculi. Clinical, biochemical and radiological studies in 619 patients.
    The Medical journal of Australia, 1971, Nov-20, Volume: 2, Issue:21

    Topics: Adolescent; Adult; Age Factors; Aged; Australia; Calcium; Child; Cystinuria; Diarrhea; Female; Human

1971
Parathyroid adenoma. An unusual presentation.
    The British journal of surgery, 1968, Volume: 55, Issue:11

    Topics: Adenoma; Anemia, Hypochromic; Arthritis; Asthenia; Calcinosis; Calcium; Female; Humans; Hypercalcemi

1968