uric acid and Neoplasms studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

Excerpt	Relevance	Reference
"Control of serum uric acid (sUA) levels is very important during chemotherapy in patients with malignant tumors, as the risks of tumor lysis syndrome (TLS) and renal events are increased with increasing levels of sUA."	9.22	Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. ( Fujimaki, K; Fujisaki, T; Gemba, K; Goto, T; Kaneko, M; Kawai, Y; Kiguchi, T; Kirito, K; Maemondo, M; Nakajima, A; Okamoto, M; Takeda, K; Tamura, K; Ueda, T, 2016)
"While rasburicase has shown efficacy to rapidly correct hyperuricemia compared with allopurinol, its overall impact in improving clinically significant outcomes, such as acute kidney injury (AKI), in tumor lysis syndrome (TLS) is unknown."	7.96	Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. ( Estey, E; Frieze, D; Garcia, DA; Hingorani, S; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020)
"The levels of CA 125 in mild and severe preeclampsia were (21."	5.91	Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023)
"Uric acid is a powerful antioxidant and is a scavenger of singlet oxygen and radicals."	5.26	Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. ( Ames, BN; Cathcart, R; Hochstein, P; Schwiers, E, 1981)
"Control of serum uric acid (sUA) levels is very important during chemotherapy in patients with malignant tumors, as the risks of tumor lysis syndrome (TLS) and renal events are increased with increasing levels of sUA."	5.22	Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. ( Fujimaki, K; Fujisaki, T; Gemba, K; Goto, T; Kaneko, M; Kawai, Y; Kiguchi, T; Kirito, K; Maemondo, M; Nakajima, A; Okamoto, M; Takeda, K; Tamura, K; Ueda, T, 2016)
"Although urate oxidase might be effective in reducing serum uric acid, it is unclear whether it reduces clinical tumour lysis syndrome, renal failure, or mortality."	4.90	Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. ( Chan, GC; Cheuk, DK; Chiang, AK; Ha, SY, 2014)
" However, ARF may also develop due to aetiologies arising from cancer treatment or the disease itself, including: nephrotoxic chemotherapy agents, post-renal obstruction, compression and infiltration by malignancy, tumour lysis syndrome, uric acid, sepsis and contrast agent nephropathy."	4.82	Acute renal failure in cancer patients. ( Flombaum, CD; Lameire, NH; Moreau, D; Ronco, C, 2005)
" Adherence to guidelines has not been well studied, and the correlation between uric acid reduction and clinically relevant outcomes, such as acute kidney injury, remains unclear."	3.96	Utilization patterns and clinical outcomes of rasburicase administration according to tumor risk stratification. ( Frieze, D; Garcia, DA; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020)
"In addition to the controversy regarding the association of hyperuricemia with mortality, uncertainty also remains regarding the association between low serum uric acid (SUA) and mortality."	3.96	U-Shaped Association of Serum Uric Acid With All-Cause and Cause-Specific Mortality in US Adults: A Cohort Study. ( Bao, H; Cheng, X; Hu, G; Hu, L; Wang, T; Xu, BP; Zhou, W; Zhu, L, 2020)
"While rasburicase has shown efficacy to rapidly correct hyperuricemia compared with allopurinol, its overall impact in improving clinically significant outcomes, such as acute kidney injury (AKI), in tumor lysis syndrome (TLS) is unknown."	3.96	Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. ( Estey, E; Frieze, D; Garcia, DA; Hingorani, S; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020)
"Rasburicase is indicated for the initial management of plasma uric acid levels in adults receiving anticancer therapy who are at risk for acute tumor lysis syndrome (TLS) and subsequent hyperuricemia."	3.76	Fixed-dose rasburicase 6 mg for hyperuricemia and tumor lysis syndrome in high-risk cancer patients. ( Shanholtz, CB; Thompson, JL; Vines, AN, 2010)
" The vast majority of these patients had a malignancy and were in danger of developing tumor lysis syndrome (TLS) and subsequent acute uric acid nephropathy (AUAN) and were unable to take oral allopurinol."	3.70	Allopurinol: intravenous use for prevention and treatment of hyperuricemia. ( Anderson, SA; Cederberg, D; Guaspari, A; Haase-Statz, S; Hohneker, JA; Smalley, RV, 2000)
"The relationships of serum uric acid to mortality from all causes, the cardiovascular diseases, and cancer were evaluated in 6797 white women age 35-64 years followed for an average of 11."	3.67	Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry. ( Dyer, AR; Levine, W; Schoenberger, JA; Shekelle, RB; Stamler, J, 1989)
"The relative risk of all cancers for high versus low SUA level was 1."	2.58	Serum uric acid and cancer mortality and incidence: a systematic review and meta-analysis. ( Boffetta, P; Dovell, F, 2018)
"Individuals with cancer are subject to fluid and electrolyte imbalances because of the original disease process, therapy, and complications resulting from both the disease process and from therapy."	2.36	Fluid and electrolyte disturbances associated with cancer and its treatment. ( Cunningham, SG, 1982)
"In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death."	2.36	Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980)
"Malignant neoplasms may cause life-threatening complications requiring prompt diagnosis and emergency therapy."	2.36	Emergencies in oncology. Current management. ( Stolinsky, DC, 1978)
"The levels of CA 125 in mild and severe preeclampsia were (21."	1.91	Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023)
"Rapid and accurate detection of cancer and neurological diseases is a major issue that has received great attention recently to enable early therapy treatment."	1.72	Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. ( Chen, YY; Chiang, WH; Fedotov, PV; Kurniawan, D; Mousavi, SM; Obraztsova, ED, 2022)
"During the follow-up period, 1619 cancer diagnoses and 617 cancer-related deaths were recorded."	1.62	Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population. ( Choi, CK; Choi, SW; Kim, HY; Kim, YR; Kweon, SS; Lee, YH; Shin, MH, 2021)
"Patients with cancer were older and more often former smokers, had lower body mass index, lower left ventricular ejection fraction (LVEF), less implanted devices, lower glucose and haemoglobin and higher uric acid levels than those without cancer."	1.56	Cancer in chronic heart failure patients in the GISSI-HF trial. ( Ameri, P; Canepa, M; Latini, R; Luigi Nicolosi, G; Maggioni, AP; Marchioli, R; Tavazzi, L, 2020)
"Using data from The Cancer Genome Atlas (TCGA), we analysed the expression levels of xanthine dehydrogenase (XDH) and adenine phosphoribosyltransferase (APRT), two key enzymes in UA production and the purine salvage pathway, respectively."	1.48	A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates. ( Ceballos-Picot, I; Chatelain, D; Chauffert, B; Dahmani, S; Galmiche, A; Guedda, S; Louandre, C; Saidak, Z; Sauzay, C, 2018)
"A total of 232 participants developed cancer."	1.46	Association of serum uric acid with increased risk of cancer among hypertensive Chinese. ( Gao, W; Gu, J; Hou, FF; Huo, Y; Jiang, H; Jiang, X; Lei, Y; Qin, X; Shen, L; Wang, B; Wang, X; Wang, Y; Xu, X; Yang, J; Zhang, R; Zhang, X; Zhao, Q, 2017)
"Hazard ratio (HR) for overall cancer for the 4th quartile of uric acid compared to the 1st was 1."	1.46	Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study. ( Garmo, H; Hammar, N; Holmberg, L; Jungner, I; Lambe, M; Malmström, H; Van Hemelrijck, M; Walldius, G; Wulaningsih, W; Yiu, A, 2017)
"A total of 8274 patients with type 2 diabetes from the Shanghai Diabetes Registry (SDR) participated."	1.43	Association between uric acid, cancer incidence and mortality in patients with type 2 diabetes: Shanghai diabetes registry study. ( Bao, Y; Deng, Z; Gu, Y; Hou, X; Hu, C; Jia, W; Zhang, L, 2016)
"We analyzed the association between cancer mortality risk and SUA level both as continuous variable and as tertiles: lowest <5 mg/dl (reference), middle 5-5."	1.40	Serum uric acid levels and cancer mortality risk among males in a large general population-based cohort study. ( Boezen, HM; Taghizadeh, N; Vonk, JM, 2014)
"A perspective adsorptive method to minimize systemic toxic effects of chemotherapy is enterosorption (ES)."	1.39	Enterosorption as a method to decrease the systemic toxicity of cisplatin. ( Bardakhivskaya, KI; Ivanyuk, AA; Korotich, VG; Maslenniy, VN; Nikolaev, VG; Nikolaeva, VV; Sakhno, LA; Shevchuk, OO; Yurchenko, OV, 2013)
"Cachexia is a common co-morbidity in cancer occurring in up to 80% of patients depending on the type of cancer."	1.38	Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. ( Adams, V; Anker, SD; Argiles, JM; Doehner, W; Hartman, K; Köhrle, J; Möller, N; Palus, S; Ruis, SB; Springer, J; Tschirner, A; von Haehling, S; Wirth, EK, 2012)
"Risk of cancer is increased in conditions associated with insulin resistance, but this could be secondary to subclinical inflammation."	1.36	Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. ( Godsland, IF; Johnston, DG; Loh, WJ; North, BV, 2010)
"Uric acid (UA) is an endogenous danger signal recently identified to be released from dying cells."	1.35	The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity. ( Behrens, MD; Disis, ML; Erskine, CL; Gad, EA; Kalli, KR; Knutson, KL; Krco, CJ; Krempski, J; Wagner, WM, 2008)
" The drug dosing was calculated based on the patients' ideal body weight (IBW) or adjusted body weight (aBW) for those who were more than 30% above their IBW."	1.35	Single-dose rasburicase for tumour lysis syndrome in adults: weight-based approach. ( Campara, M; Haaf, CM; Shord, SS, 2009)
"During follow-up 5189 incident cancers were observed."	1.35	Use of penalized splines in extended Cox-type additive hazard regression to flexibly estimate the effect of time-varying serum uric acid on risk of cancer incidence: a prospective, population-based study in 78,850 men. ( Brant, LJ; Concin, H; Diem, G; Hilbe, W; Kaltenbach, L; Klenk, J; Kneib, T; Lang, S; Oberaigner, W; Pfeiffer, KP; Ruttmann, E; Strasak, AM; Ulmer, H, 2009)
"71 mg/dl) was independently associated with increased risk of mortality from all cancers, showing a clear dose-response relationship (p for trend < 0."	1.34	Serum uric acid and risk of cancer mortality in a large prospective male cohort. ( Concin, H; Diem, G; Hilbe, W; Oberaigner, W; Pfeiffer, KP; Rapp, K; Ruttmann, E; Strasak, AM; Ulmer, H, 2007)
"Thus, cancer cells can no longer divide and cancer activity is inhibited."	1.34	Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im ( Chen, Y; Duvvi, H; Lu, DP; Ohki, M; Omura, Y; Shimotsura, Y, 2007)
"One hundred eighteen terminally ill cancer patients, including 63 (53."	1.33	Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients. ( Cho, KH; Lee, DC; Lee, HR; Shim, JY; Shin, HS; Suh, SY, 2006)
"The data suggest cancer-related diminished synthesis of cholesterol and, generally, a greater antioxidant burden for alpha-tocopherol than urate in cancer-generated oxidative stress."	1.31	Serum antioxidant and cholesterol levels in patients with different types of cancer. ( Abiaka, C; Al-Awadi, F; Al-Sayer, H; Behbehani, A; Farghally, M; Gulshan, S; Simbeye, A, 2001)
"We analyzed cancer mortality trends in 3282 elderly subjects from two general Italian populations with different life-style patterns taking part in the Cardiovascular Study in the Elderly (CASTEL)."	1.30	Cancer mortality trends in two cohorts of elderly people having different life-styles. ( Biasin, R; Casiglia, E; Mazza, A; Pessina, AC; Pizziol, A; Privato, G; Scarpa, R; Sica, E, 1999)
"RR of cancer mortality increased with increasing ALT or ALP."	1.30	Predictors of cancer mortality in elderly subjects. ( Casiglia, E; Mazza, A; Pessina, AC; Pizziol, A; Scarpa, R; Sica, E; Tikhonoff, V, 1999)
"Fifty patients with advanced cancer were treated at dose levels that ranged from 100 to 1500 mg/m2/day."	1.28	Phase I clinical and pharmacological study of merbarone. ( Baltzer, L; Dimaggio, JJ; Haines, I; Lee, SJ; Lowenthal, DA; Muindi, J; Stevens, YW; Walsh, TD; Warrell, RP; Yaldaei, S, 1990)
"Blood uric acid was measured in 316 cancer patients, 173 men and 143 women and was found higher in all patients than in normal subjects."	1.28	[Cancer and hyperuricemia--an analysis of 316 cancer patients]. ( Dai, R, 1989)
"When the deaths from cancer were classified as "early" or "late"--that is, occurring less than or more than 2."	1.27	Raised serum urate concentration as risk factor for premature mortality in middle aged men: relation to death from cancer. ( Petersson, B; Trell, E, 1983)
"Total cancer incidence as well as site-specific incidence (for lung, colon, and prostate cancer in men and lung, colon, breast, uterine, and cervical cancer in women) was ascertained from hospital discharge records and the Surveillance, Epidemiology and End Results program in the San Francisco-Oakland Bay area."	1.27	Serum uric acid unrelated to cancer incidence in humans. ( Fireman, BH; Hiatt, RA, 1988)
"Uric acid was used as an indicator for tissue-breakdown."	1.27	beta-Aminoisobutyric acid as a marker of thymine catabolism in malignancy. ( Abeling, NG; van Bree-Blom, EJ; van Erven, AJ; van Gennip, AH; Voûte, PA, 1987)
"Patients with sepsis or acute pancreatitis had drastically reduced levels of total muscular free AA, mainly due to a fall in muscle glutamine."	1.27	[Amino acid and protein metabolism in critically ill patients]. ( Roth, E, 1985)
"Tiazofurin levels were measured using a high-pressure liquid chromatography assay, and pharmacokinetic studies were performed in patients treated at each dose level."	1.27	Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193). ( Boldt, DH; Clark, GM; Hersh, MR; Kuhn, JG; Melink, TJ; Patton, TF; Siegler, R; Sternson, LA; Von Hoff, DD, 1985)
"Uric acid is a powerful antioxidant and is a scavenger of singlet oxygen and radicals."	1.26	Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. ( Ames, BN; Cathcart, R; Hochstein, P; Schwiers, E, 1981)
"Post-operative care of cancer patients has to take into consideration additional diseases not related to the basic disease, too."	1.26	[Secondary diseases complicating cancer]. ( Kirsch, JJ; Müller, J; Pitule-Schödel, H, 1981)
"Sixty-six patients with metastatic cancer whose bone marrow biopsies were negative, served as controls."	1.26	Variables predictive of bone marrow metastasis. ( Chernow, B; Wallner, SF, 1978)
"Forty patients with generalized cancer complicated by water and electrolyte retention were treated with "medium" and "large" doses of furosemide and bumetanide with 35% and 40% objective positive response, respectively."	1.26	Diuretics in malignant effusions and edemas of generalized cancer. ( Athanasiou, A; Dadiotis, L; Razis, DV, 1976)

Timeframe	Studies, this research(%)	All Research%
pre-1990	73 (45.34)	18.7374
1990's	15 (9.32)	18.2507
2000's	22 (13.66)	29.6817
2010's	31 (19.25)	24.3611
2020's	20 (12.42)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00187005]	Phase 3	53 participants (Actual)	Interventional	1998-07-31	Terminated (stopped due to Toxicity)
[NCT00005140]		0 participants	Observational	1977-09-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
The double faced role of xanthine oxidoreductase in cancer. Acta pharmacologica Sinica, 2022, Volume: 43, Issue:7 Topics: Humans; Hyperuricemia; Neoplasms; Reactive Oxygen Species; Uric Acid; Xanthine Dehydrogenase	2022
A lex naturalis delineates components of a human-specific, adrenal androgen-dependent, p53-mediated 'kill switch' tumor suppression mechanism. Endocrine-related cancer, 2020, Volume: 27, Issue:2 Topics: Androgens; Biological Evolution; Body Size; Dehydroepiandrosterone Sulfate; Glucosephosphate Dehydro	2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors. Annales medico-psychologiques, 2021, Volume: 179, Issue:2 Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli	2021
Serum uric acid and cancer mortality and incidence: a systematic review and meta-analysis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2018, Volume: 27, Issue:4 Topics: Biomarkers, Tumor; Humans; Incidence; Neoplasms; Prognosis; United States; Uric Acid	2018
Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. The Cochrane database of systematic reviews, 2014, Aug-14, Issue:8 Topics: Adolescent; Allopurinol; Antimetabolites; Area Under Curve; Child; Controlled Clinical Trials as Top	2014
Serum Uric Acid Increases Risk of Cancer Incidence and Mortality: A Systematic Review and Meta-Analysis. Mediators of inflammation, 2015, Volume: 2015 Topics: Antioxidants; Data Collection; Data Interpretation, Statistical; Female; Humans; Incidence; Male; Ne	2015
Xanthine oxidoreductase in cancer: more than a differentiation marker. Cancer medicine, 2016, Volume: 5, Issue:3 Topics: Animals; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Prognosis; Reactive Nitrogen Spe	2016
Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. The Cochrane database of systematic reviews, 2017, 03-08, Volume: 3 Topics: Adolescent; Allopurinol; Antimetabolites; Area Under Curve; Child; Controlled Clinical Trials as Top	2017
Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer. The Cochrane database of systematic reviews, 2010, Jun-16, Issue:6 Topics: Allopurinol; Antimetabolites; Child; Controlled Clinical Trials as Topic; Humans; Neoplasms; Randomi	2010
Nanomaterial-based functional scaffolds for amperometric sensing of bioanalytes. Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:11 Topics: Animals; Biosensing Techniques; Blood Glucose; Cholesterol; Electrochemical Techniques; Equipment De	2013
[Secondary hypouricemia in patients with malignant disease]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1 Topics: Acute Disease; Humans; Kidney; Leukemia; Lymphoma; Multiple Myeloma; Neoplasms; Neural Tube Defects;	2003
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Acute renal failure in cancer patients. Annals of medicine, 2005, Volume: 37, Issue:1 Topics: Acute Kidney Injury; Antineoplastic Agents; Humans; Hyperuricemia; Neoplasms; Prognosis; Risk Factor	2005
Tumor lysis syndrome. Seminars in thrombosis and hemostasis, 2007, Volume: 33, Issue:4 Topics: Biomarkers; Humans; Kidney Diseases; Neoplasms; Tumor Lysis Syndrome; Uric Acid	2007
Dendritic cells and innate defense against tumor cells. Cytokine & growth factor reviews, 2008, Volume: 19, Issue:1 Topics: Apoptosis; Benzamides; Biomarkers, Tumor; Cancer Vaccines; CpG Islands; Cytokines; Dendritic Cells;	2008
The detection of environmental mutagens and potential carcinogens. Cancer, 1984, May-15, Volume: 53, Issue:10 Topics: Aging; Animals; Biological Assay; Biotransformation; Carcinogens, Environmental; DNA; DNA Repair; Fe	1984
Renal manifestations of extrarenal neoplasms. Human pathology, 1980, Volume: 11, Issue:1 Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm	1980
Fluid and electrolyte disturbances associated with cancer and its treatment. The Nursing clinics of North America, 1982, Volume: 17, Issue:4 Topics: Blood Volume; Body Water; Calcium; Humans; Hypercalcemia; Hyperkalemia; Hypocalcemia; Hypokalemia; I	1982
Cancer and the kidney: complications of neoplasms. The American journal of medicine, 1981, Volume: 71, Issue:4 Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypercalcemia; I	1981
Emergencies in oncology. Current management. The Western journal of medicine, 1978, Volume: 129, Issue:3 Topics: Airway Obstruction; Brain Neoplasms; Cardiac Tamponade; Embolism; Emergencies; Humans; Hypercalcemia	1978
Common emergencies in cancer medicine: metabolic syndromes. Journal of the National Medical Association, 1991, Volume: 83, Issue:9 Topics: Acidosis, Lactic; Acute Kidney Injury; Adrenal Cortex Diseases; Emergencies; Humans; Hypercalcemia;	1991
[Isolation of factors responsible for the immunosuppression found in tumor-bearing animals]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1985, Volume: 105, Issue:2 Topics: Adenosine; Animals; Glycoproteins; Humans; Immune Tolerance; Macrophage Activation; Macrophages; Mic	1985
Cancer chemotherapy. 3. New York state journal of medicine, 1972, Nov-15, Volume: 72, Issue:22 Topics: Abnormalities, Drug-Induced; Alkylating Agents; Allopurinol; Alopecia; Antimetabolites; Antineoplast	1972
Uric acid nephrolithiasis. The American journal of medicine, 1968, Volume: 45, Issue:5 Topics: Adolescent; Aged; Allopurinol; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Met	1968
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture. Cancer research, 1969, Volume: 29, Issue:11 Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors;	1969

Article	Year
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors. Annales medico-psychologiques, 2021, Volume: 179, Issue:2 Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli	2021
Plasma Urate, Cancer Incidence, and All-Cause Mortality: A Mendelian Randomization Study. Clinical chemistry, 2017, Volume: 63, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Alleles; Cause of Death; Genotype; Glucose Transport Proteins, Facil	2017
Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. International journal of clinical oncology, 2016, Volume: 21, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hy	2016
Recombinant urate oxidase (rasburicase) in the prevention and treatment of malignancy-associated hyperuricemia in pediatric and adult patients: results of a compassionate-use trial. Leukemia, 2001, Volume: 15, Issue:10 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Humans; In	2001
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10 Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolenc	2001
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Article	Year
Pseudo-tumor of the patella due to gout tophi. Joint bone spine, 2022, Volume: 89, Issue:1 Topics: Arthritis, Gouty; Gout; Humans; Neoplasms; Patella; Uric Acid	2022
Diagnostic Value of Lactate Dehydrogenase and Uric Acid as Screening Tools for Malignancies in Children. Pediatric emergency care, 2022, Jun-01, Volume: 38, Issue:6 Topics: Biomarkers; Child; Humans; L-Lactate Dehydrogenase; Neoplasms; Retrospective Studies; ROC Curve; Uri	2022
Incidence and Risk Factors for Acute Kidney Injury After Chimeric Antigen Receptor T-Cell Therapy. Mayo Clinic proceedings, 2022, Volume: 97, Issue:7 Topics: Acute Kidney Injury; Antigens, CD19; Cell- and Tissue-Based Therapy; Contrast Media; Creatine Kinase	2022
Renal NF-κB activation impairs uric acid homeostasis to promote tumor-associated mortality independent of wasting. Immunity, 2022, 09-13, Volume: 55, Issue:9 Topics: Animals; Carrier Proteins; Drosophila; Homeostasis; Neoplasms; NF-kappa B; Uric Acid	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. Journal of materials chemistry. B, 2022, 11-30, Volume: 10, Issue:46 Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots;	2022
Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. PloS one, 2023, Volume: 18, Issue:1 Topics: C-Reactive Protein; CA-125 Antigen; Case-Control Studies; Female; Humans; Inflammation Mediators; Ne	2023
U-Shaped Association of Serum Uric Acid With All-Cause and Cause-Specific Mortality in US Adults: A Cohort Study. The Journal of clinical endocrinology and metabolism, 2020, 01-01, Volume: 105, Issue:1 Topics: Adult; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Hyperuricemia; Male;	2020
Predictive factors of tumour necrosis inhibitor treatment persistence for rheumatoid arthritis: An observational study in 8052 patients. Joint bone spine, 2020, Volume: 87, Issue:2 Topics: Aged; Arthritis, Rheumatoid; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Necrosis; N	2020
Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. Leukemia research, 2020, Volume: 89 Topics: Adult; Allopurinol; Female; Humans; Hyperuricemia; Kaplan-Meier Estimate; Male; Middle Aged; Neoplas	2020
The coadministration of trehalose dibehenate and monosodium urate crystals promotes an antitumor phenotype in human-derived myeloid cells. Immunology and cell biology, 2020, Volume: 98, Issue:5 Topics: Animals; Humans; Macrophages; Mice; Monocytes; Neoplasms; Phenotype; Trehalose; Uric Acid	2020
Cancer in chronic heart failure patients in the GISSI-HF trial. European journal of clinical investigation, 2020, Volume: 50, Issue:9 Topics: Aged; Blood Pressure; Cardiovascular Diseases; Cause of Death; Cholesterol; Chronic Disease; Creatin	2020
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity. Cell biochemistry and biophysics, 2021, Volume: 79, Issue:1 Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation	2021
Identification of two novel subgroups in patients with diabetes mellitus and their association with clinical outcomes: A two-step cluster analysis. Journal of diabetes investigation, 2021, Volume: 12, Issue:8 Topics: Adult; Age of Onset; Aged; Body Mass Index; China; Cluster Analysis; Cohort Studies; Diabetes Compli	2021
Is there relationship between serum uric acid levels and lower urinary tract symptoms, prostate volume, and PSA in men without cancer? A prospective population-based study. Andrologia, 2021, Volume: 53, Issue:10 Topics: Aged; Humans; Lower Urinary Tract Symptoms; Male; Middle Aged; Neoplasms; Prospective Studies; Prost	2021
Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population. Yonsei medical journal, 2021, Volume: 62, Issue:9 Topics: Bilirubin; Humans; Male; Neoplasms; Prospective Studies; Republic of Korea; Serum Albumin; Uric Acid	2021
Nutrition Status and Renal Function as Predictors in Acute Myocardial Infarction with and without Cancer: A Single Center Retrospective Study. Nutrients, 2021, Jul-30, Volume: 13, Issue:8 Topics: Aged; Female; Humans; Kidney; Logistic Models; Male; Middle Aged; Myocardial Infarction; Neoplasms;	2021
Association of serum uric acid with increased risk of cancer among hypertensive Chinese. International journal of cancer, 2017, 07-01, Volume: 141, Issue:1 Topics: Adult; Aged; Asian People; China; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Ag	2017
Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study. Oncotarget, 2017, Jun-27, Volume: 8, Issue:26 Topics: Female; Follow-Up Studies; Humans; Incidence; Male; Neoplasms; Population Surveillance; Proportional	2017
Albumin, bilirubin, uric acid and cancer risk: results from a prospective population-based study. British journal of cancer, 2017, Nov-07, Volume: 117, Issue:10 Topics: Adult; Aged; Bilirubin; Cohort Studies; Female; Humans; Male; Middle Aged; Neoplasms; Proportional H	2017
A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates. Bioscience reports, 2018, 10-31, Volume: 38, Issue:5 Topics: Adenine Phosphoribosyltransferase; Databases, Factual; DNA Copy Number Variations; DNA Methylation;	2018
[Study of arginase activity of mixed saliva in cancer]. Voprosy onkologii, 2016, Volume: 62, Issue:5 Topics: Adult; Aged; Arginase; Female; Humans; Male; Middle Aged; Neoplasm Proteins; Neoplasms; Nitric Oxide	2016
Crystal-proven gout patients have an increased mortality due to cardiovascular diseases, cancer, and infectious diseases especially when having tophi and/or high serum uric acid levels: a prospective cohort study. Clinical rheumatology, 2019, Volume: 38, Issue:5 Topics: Aged; Cardiovascular Diseases; Cause of Death; Communicable Diseases; Female; Gout; Humans; Hyperuri	2019
Utilization patterns and clinical outcomes of rasburicase administration according to tumor risk stratification. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:3 Topics: Acute Kidney Injury; Aged; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Neop	2020
Enterosorption as a method to decrease the systemic toxicity of cisplatin. Experimental oncology, 2013, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Agents; Body Weight; Carbon; Cisplatin; Creatinine; Enterosorption; Kidney;	2013
The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. Oncogene, 2015, Apr-02, Volume: 34, Issue:14 Topics: Antioxidants; Biological Transport; Cell Line, Tumor; DNA Damage; Glucose Transport Proteins, Facili	2015
Serum uric acid levels and cancer mortality risk among males in a large general population-based cohort study. Cancer causes & control : CCC, 2014, Volume: 25, Issue:8 Topics: Adult; Cohort Studies; Colorectal Neoplasms; Humans; Lung Neoplasms; Male; Neoplasms; Netherlands; P	2014
Extreme clinical chemistry. Clinica chimica acta; international journal of clinical chemistry, 2015, Aug-25, Volume: 448 Topics: Biomarkers; Chemistry, Clinical; Humans; Metabolic Diseases; Neoplasms; Serum Albumin; Tangier Disea	2015
High Serum Uric Acid Levels Are Associated with All-Cause and Cardiovascular, but Not Cancer, Mortality in Elderly Adults. Journal of the American Geriatrics Society, 2015, Volume: 63, Issue:9 Topics: Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Male; Neoplasms; Risk	2015
Association between uric acid, cancer incidence and mortality in patients with type 2 diabetes: Shanghai diabetes registry study. Diabetes/metabolism research and reviews, 2016, Volume: 32, Issue:3 Topics: Aged; China; Diabetes Mellitus, Type 2; Female; Humans; Hyperuricemia; Incidence; Male; Middle Aged;	2016
Monosodium Urate Crystals Induce Upregulation of NK1.1-Dependent Killing by Macrophages and Support Tumor-Resident NK1.1+ Monocyte/Macrophage Populations in Antitumor Therapy. Journal of immunology (Baltimore, Md. : 1950), 2015, Dec-01, Volume: 195, Issue:11 Topics: Animals; Antigens, Ly; Carrier Proteins; Cell Line, Tumor; Granzymes; Inflammasomes; Interleukin-1be	2015
Uric acid enhances the antitumor immunity of dendritic cell-based vaccine. Scientific reports, 2015, Nov-10, Volume: 5 Topics: Adjuvants, Immunologic; Adoptive Transfer; Animals; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cyt	2015
High Uric Acid (UA) Negatively Affects Serum Tartrate-Resistant Acid Phosphatase 5b (TRACP 5b) Immunoassay. PloS one, 2016, Volume: 11, Issue:1 Topics: Acid Phosphatase; Adolescent; Adult; Aged; Biomarkers, Tumor; Bone Neoplasms; Bone Resorption; Case-	2016
Prevalence and possible causes of hypouricemia at a tertiary care hospital. The Korean journal of internal medicine, 2016, Volume: 31, Issue:5 Topics: Adult; Aged; Allopurinol; Angiotensin Receptor Antagonists; Diabetes Mellitus; Female; Humans; Male;	2016
[Analysis of the 2015 British guidelines on the prevention and management of tumor lysis syndrome]. La Revue de medecine interne, 2017, Volume: 38, Issue:1 Topics: Adult; Allopurinol; Child; Hematologic Neoplasms; Humans; Incidence; Neoplasms; Practice Guidelines	2017
Use of penalized splines in extended Cox-type additive hazard regression to flexibly estimate the effect of time-varying serum uric acid on risk of cancer incidence: a prospective, population-based study in 78,850 men. Annals of epidemiology, 2009, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Humans; Incidence; Male; Middle Aged; Neopla	2009
Single-dose rasburicase for tumour lysis syndrome in adults: weight-based approach. Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2 Topics: Aged; Antineoplastic Agents; Creatinine; Drug Costs; Female; Gout Suppressants; Humans; Hyperuricemi	2009
Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. Cancer causes & control : CCC, 2010, Volume: 21, Issue:5 Topics: Biomarkers; Blood Glucose; Cholesterol, HDL; England; Follow-Up Studies; Glucose Intolerance; Humans	2010
Blood uric acid and proteose, body temperature, and glomerular clearance of rabbits implanted with the Brown-Pearce carcinoma and treated with the polysaccharide from Serratia marcescens. Journal of the National Cancer Institute, 1946, Volume: 7, Issue:3 Topics: Animals; Bacteria; Blood; Body Temperature; Carcinoma, Brown-Pearce; Humans; Kidney; Neoplasms; Neop	1946
Fixed-dose rasburicase 6 mg for hyperuricemia and tumor lysis syndrome in high-risk cancer patients. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Creatinine; Dose-Response Relationship, Drug; Drug Administration Sc	2010
World congress on insulin resistance, diabetes, and cardiovascular disease: Part 1. Diabetes care, 2011, Volume: 34, Issue:7 Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, T	2011
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. International journal of cancer, 2012, Nov-01, Volume: 131, Issue:9 Topics: Allopurinol; Animals; Body Composition; Body Weight; Cachexia; Caspase 3; Enzyme Inhibitors; Male; N	2012
Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7 Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Carbon Radioisotopes; Creatinine; Cys	2012
Catabolism of xanthine and uracil in tumor-bearing rats. Cancer research, 1962, Volume: 22 Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Hydantoins; Liver Neoplasms; Neoplasms; N	1962
THE BENIGN PURPURIC HYPERGLOBULINEMIA OF WALDENSTROM. JAMA, 1964, Jan-18, Volume: 187 Topics: Blood; Blood Proteins; Collagen Diseases; Humans; Neoplasms; Purpura; Purpura, Hyperglobulinemic; Rh	1964
THE BIOCHEMICAL BASIS FOR THE DIFFERENTIAL SENSITIVITY OF INTESTINAL MUCOSA AND BONE MARROW TO 6-THIOGUANINE. Cancer research, 1963, Volume: 23 Topics: Antineoplastic Agents; Bone Marrow; Intestinal Mucosa; Intestine, Small; Intestines; Metabolism; Neo	1963
PROTEIN-BOUND DYE AND PURINE-CATABOLYZING ENZYMES IN PARENCHYMAL AND NONPARENCHYMAL CELLS OF RATS FED 4-DIMETHYLAMINOAZOBENZENE. Cancer research, 1964, Volume: 24 Topics: Azo Compounds; Carcinogens; Enzymes; Guanine; Histocytochemistry; Liver; Liver Neoplasms; N-Glycosyl	1964
ANURIA DUE TO URIC ACID CRYSTALLURIA: AN UNUSUAL COMPLICATION OF THERAPY IN THE RETICULOSES. British journal of cancer, 1964, Volume: 18 Topics: Abdominal Neoplasms; Anuria; Blood; Genetic Diseases, X-Linked; Humans; Kidney Diseases; Leukemia, H	1964
ACUTE RENAL FAILURE COMPLICATING LYMPHOSARCOMA. British medical journal, 1965, Feb-27, Volume: 1, Issue:5434 Topics: Acute Kidney Injury; Blood; Humans; Kidney; Kidneys, Artificial; Lymphoma; Lymphoma, Non-Hodgkin; Ne	1965
URIC ACID IN HUMAN PLASMA. II. INVESTIGATIONS ON THE POSSIBLE PRESENCE OF URIC ACID COVALENTLY LINKED TO PLASMA MACROMOLECULES. Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17 Topics: Arthritis; Arthritis, Rheumatoid; Blood; Chromatography; Chromatography, Gel; Female; Gout; Humans;	1965
[STUDY OF KREBS CYCLE ACIDS IN CANCER]. Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20 Topics: Acids; Arthritis; Arthritis, Rheumatoid; Breast Neoplasms; Chromatography; Citric Acid Cycle; Female	1964
PREVENTION OF HYPERURICEMIA IN LEUKEMIA AND LYMPHOMA: USE OF ALOPURINOL, A XANTHINE OXIDASE INHIBITOR. JAMA, 1965, Jul-05, Volume: 193 Topics: Adolescent; Antineoplastic Agents; Blood; Blood Urea Nitrogen; Drug Therapy; Geriatrics; Humans; Hyp	1965
Serum uric acid and risk of death from cancer, cardiovascular disease or all causes in men. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2004, Volume: 11, Issue:3 Topics: Adult; Age Factors; Aged; Diabetes Mellitus; Follow-Up Studies; Humans; Korea; Male; Middle Aged; Mu	2004
Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study. Archives of internal medicine, 2004, Jul-26, Volume: 164, Issue:14 Topics: Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; Finland; Follow-Up Studies;	2004
Uric acid and allantoin excretion in normal and tumor-bearing mice. The Journal of biological chemistry, 1949, Volume: 181, Issue:1 Topics: Allantoin; Animals; Biological Transport; Body Fluids; Mice; Neoplasms; Uric Acid	1949
Reduced-dose rasburicase in the treatment of adults with hyperuricemia associated with malignancy. Pharmacotherapy, 2006, Volume: 26, Issue:2 Topics: Aged; Antineoplastic Agents; Creatinine; Female; Humans; Hyperuricemia; Leukemia; Lymphoma; Male; Mi	2006
Reduced-dose rasburicase (recombinant xanthine oxidase) in adult cancer patients with hyperuricemia. Bone marrow transplantation, 2006, Volume: 37, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Creatinine; Female; Hematopoietic Stem Cell Transplantation; Humans;	2006
Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients. Journal of pain and symptom management, 2006, Volume: 31, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Male; Middle Aged; Neoplasms; Predic	2006
Effects of basal level of antioxidants on oxidative DNA damage in humans. European journal of nutrition, 2007, Volume: 46, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Antioxidants; Biomarkers; Chromatograph	2007
Serum uric acid and risk of cancer mortality in a large prospective male cohort. Cancer causes & control : CCC, 2007, Volume: 18, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Follow-Up Studies; Humans; Longitudinal	2007
The role of serum uric acid as an antioxidant protecting against cancer: prospective study in more than 28 000 older Austrian women. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:11 Topics: Age Factors; Aged; Aged, 80 and over; Antioxidants; Austria; Biomarkers, Tumor; Cohort Studies; Fema	2007
Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation. Oncogene, 2008, Apr-10, Volume: 27, Issue:17 Topics: Adenoviridae; Cell Line, Tumor; Dendritic Cells; Enzyme Activation; Humans; Neoplasms; Oncolytic Vir	2008
The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity. Blood, 2008, Feb-01, Volume: 111, Issue:3 Topics: Animals; Antibodies; Cell Differentiation; Cell Line, Tumor; Crystallization; Interleukin-5; Leukocy	2008
Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im Acupuncture & electro-therapeutics research, 2007, Volume: 32, Issue:1-2 Topics: Acupuncture; Acupuncture Points; Blood Cell Count; Blood Glucose; C-Reactive Protein; Cardiovascular	2007
Allopurinol in the treatment of neoplastic disease complicated by hyperuricemia. Archives of internal medicine, 1967, Volume: 120, Issue:1 Topics: Adult; Aged; Allopurinol; Enzyme Therapy; Enzymes; Female; Humans; Kidney; Male; Middle Aged; Neopla	1967
Hypouricaemic effect of polyethyleneglycol modified urate oxidase. Lancet (London, England), 1981, Aug-08, Volume: 2, Issue:8241 Topics: Aged; Allantoin; Allopurinol; Candida; Humans; Male; Middle Aged; Neoplasms; Polyethylene Glycols; U	1981
Raised serum urate concentration as risk factor for premature mortality in middle aged men: relation to death from cancer. British medical journal (Clinical research ed.), 1983, Jul-02, Volume: 287, Issue:6384 Topics: Body Weight; Cholesterol; Creatinine; Humans; Male; Middle Aged; Neoplasms; Risk; Uric Acid	1983
Raised serum urate concentration as risk factor for premature mortality in middle aged men. British medical journal (Clinical research ed.), 1984, Apr-14, Volume: 288, Issue:6424 Topics: Adult; Aged; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Neoplasms; Risk; Uric Acid	1984
Hypoxanthine concentrations in normal subjects and patients with solid tumors and leukemia. Cancer research, 1984, Volume: 44, Issue:7 Topics: Acute Disease; Allopurinol; Bone Marrow; Cell Division; Cell Line; Chromatography, High Pressure Liq	1984
Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:11 Topics: Adult; Aging; Animals; Antioxidants; Ascorbic Acid; Biological Evolution; Brain; Digestive System; E	1981
The clinical pharmacology of the adenosine deaminase inhibitor 2'-deoxycoformycin. Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:2 Topics: Adenosine Deaminase Inhibitors; Adult; Aged; Animals; Coformycin; Dogs; Female; Humans; Kinetics; Le	1980
Renal and metabolic toxicities of cancer chemotherapy. Seminars in oncology, 1982, Volume: 9, Issue:1 Topics: Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Electrolytes; Glomerular Filtration	1982
[Secondary diseases complicating cancer]. Medizinische Klinik, 1981, Jul-03, Volume: 76, Issue:14 Topics: Cardiovascular Diseases; Coronary Disease; Diabetes Complications; Female; Heart Failure; Humans; Li	1981
Urolithiasis in hyperuricemia and gout. The Journal of urology, 1981, Volume: 126, Issue:4 Topics: Adult; Allopurinol; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Myelo	1981
Tumoural hypouricemia. Advances in experimental medicine and biology, 1980, Volume: 122A Topics: Autoanalysis; Creatinine; Humans; Neoplasms; Pyrazinamide; Uric Acid	1980
Hypouricaemia in a hospital population. Scandinavian journal of clinical and laboratory investigation, 1993, Volume: 53, Issue:8 Topics: Diabetes Mellitus; Female; Humans; Intensive Care Units; Male; Neoplasms; Sex Factors; Uric Acid	1993
Renal, metabolic, and hemodynamic side-effects of interleukin-2 and/or interferon alpha: evidence of a risk/benefit advantage of subcutaneous therapy. Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:12 Topics: Adult; Aged; Blood Proteins; Blood Urea Nitrogen; Creatinine; Electrolytes; Female; Hemodynamics; Hu	1993
Serum carotenoids and uric acid levels in relation to cancer. Journal of clinical pharmacy and therapeutics, 1996, Volume: 21, Issue:5 Topics: Adult; Aged; Carotenoids; Female; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Uric Ac	1996
Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid. The Biochemical journal, 1997, Jul-01, Volume: 325 ( Pt 1) Topics: Antioxidants; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Female; Glutathione; Glutathione Disulfid	1997
Serum selenium levels as indicators of body status in cancer patients and their relationship with other nutritional and biochemical markers. The Science of the total environment, 1998, Apr-08, Volume: 212, Issue:2-3 Topics: Adult; Aged; Aged, 80 and over; Aging; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers	1998
Cancer mortality trends in two cohorts of elderly people having different life-styles. Aging (Milan, Italy), 1999, Volume: 11, Issue:1 Topics: Age Distribution; Aged; Aging; Alanine Transaminase; Alkaline Phosphatase; Body Mass Index; Cohort S	1999
Predictors of cancer mortality in elderly subjects. European journal of epidemiology, 1999, Volume: 15, Issue:5 Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Body Mass Index; Cholesterol; Fe	1999
Allopurinol: intravenous use for prevention and treatment of hyperuricemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:8 Topics: Adult; Allopurinol; Child; Enzyme Inhibitors; Humans; Infusions, Intravenous; Kidney Diseases; Neopl	2000
Serum antioxidant and cholesterol levels in patients with different types of cancer. Journal of clinical laboratory analysis, 2001, Volume: 15, Issue:6 Topics: Adult; alpha-Tocopherol; Antioxidants; Arabs; Case-Control Studies; Child; Cholesterol; Chromatograp	2001
[Basic therapy in children with leukemia and a malignant tumors. II]. Kinderarztliche Praxis, 1978, Volume: 46, Issue:3 Topics: Allopurinol; Anaphylaxis; Anemia; Antibiotics, Antineoplastic; Bicarbonates; Blood Transfusion; Chil	1978
Acute renal failure associated with neoplastic disease and its treatment. Seminars in oncology, 1978, Volume: 5, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Female; Humans; Hyperc	1978
Ampicillin rash and hyperuricemia. Annals of internal medicine, 1979, Volume: 91, Issue:2 Topics: Allopurinol; Ampicillin; Drug Eruptions; Drug Interactions; Humans; Immunosuppression Therapy; Neopl	1979
[Frequency and distribution of types of hyperlipoproteinemia with life-shortening risk factors among ambulant patients (author's transl)]. Medizinische Klinik, 1975, Jul-11, Volume: 70, Issue:28-29 Topics: Cholesterol; Diabetes Complications; Female; Germany, West; Gout; Humans; Hyperlipidemias; Hypertens	1975
[Hypouricaemia (author's transl)]. La Nouvelle presse medicale, 1979, Dec-24, Volume: 8, Issue:50 Topics: Allopurinol; Fanconi Syndrome; Humans; Liver Diseases; Neoplasms; Purine-Pyrimidine Metabolism, Inbo	1979
Simultaneous analysis of substrates, products, and inhibitors of xanthine oxidase by high-pressure liquid chromatography and gas chromatography. Analytical biochemistry, 1979, Sep-15, Volume: 98, Issue:1 Topics: Allopurinol; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Hypoxanthines; Neopl	1979
[Treatment-induced complications and frequent errors in cytostatic therapy]. Schweizerische medizinische Wochenschrift, 1978, Aug-12, Volume: 108, Issue:32 Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Hum	1978
Variables predictive of bone marrow metastasis. Cancer, 1978, Volume: 42, Issue:5 Topics: Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Bone and Bones; Bone Marrow Diseases; Bone M	1978
Pharmacological and biochemical effects of pyrazofurin in humans. Cancer research, 1977, Volume: 37, Issue:7 Pt 1 Topics: Amides; Antibiotics, Antineoplastic; Drug Administration Schedule; Female; Half-Life; Humans; Infusi	1977
Hyperuricaemia as an index of the response to chemotherapy in solid tumors. Neoplasma, 1977, Volume: 24, Issue:4 Topics: Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Neoplasms; Prognosis;	1977
Diuretics in malignant effusions and edemas of generalized cancer. Journal of medicine, 1976, Volume: 7, Issue:6 Topics: Ascites; Body Weight; Bumetanide; Diuretics; Drinking; Edema; Furosemide; Humans; Neoplasms; Pleuris	1976
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin]. Voprosy onkologii, 1975, Volume: 21, Issue:11 Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C	1975
Selenium, retinol, retinol-binding protein, and uric acid: from epidemiology to clinical prevention trials. Annals of epidemiology, 1992, Volume: 2, Issue:3 Topics: Biomarkers; Biomarkers, Tumor; Humans; Neoplasms; Retinol-Binding Proteins; Selenium; Uric Acid; Vit	1992
Urate metabolism during bone marrow transplantation. Bone marrow transplantation, 1992, Volume: 10, Issue:4 Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined M	1992
Selenium, retinol, retinol-binding protein, and uric acid. Associations with cancer mortality in a population-based prospective case-control study. Annals of epidemiology, 1991, Volume: 1, Issue:5 Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Male; Neoplasms;	1991
Selenium, retinol, retinol-binding protein, and uric acid. From epidemiology to clinical prevention trials. Annals of epidemiology, 1991, Volume: 1, Issue:5 Topics: Humans; Neoplasms; Retinol-Binding Proteins; Selenium; Uric Acid; Vitamin A	1991
Clinical significance of hypouricemia in hospitalized patients. Journal of medicine, 1991, Volume: 22, Issue:2 Topics: Adolescent; Adult; Aged; Allopurinol; Anti-Bacterial Agents; Antineoplastic Agents; Child; Female; G	1991
Phase I clinical and pharmacological study of merbarone. Cancer research, 1990, Feb-15, Volume: 50, Issue:4 Topics: Adult; Aged; Antineoplastic Agents; Creatinine; Drug Administration Schedule; Drug Evaluation; Femal	1990
Explanations for the hypouricemia noted in cancer patients. Medical hypotheses, 1990, Volume: 32, Issue:2 Topics: Anorexia; Humans; Neoplasms; Uric Acid	1990
[Cancer and hyperuricemia--an analysis of 316 cancer patients]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 1989, Volume: 11, Issue:6 Topics: Adult; Aged; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neoplasms; Uric Acid; Urinary Blad	1989
Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry. Journal of clinical epidemiology, 1989, Volume: 42, Issue:3 Topics: Adult; Cardiovascular Diseases; Coronary Disease; Female; Humans; Male; Middle Aged; Mortality; Neop	1989
Serum urate level and cancer. Medical hypotheses, 1989, Volume: 28, Issue:3 Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasms; Uric Acid	1989
[How to prevent the tumor lysis syndrome]. Presse medicale (Paris, France : 1983), 1985, Dec-07, Volume: 14, Issue:42 Topics: Anuria; Humans; Neoplasms; Phosphates; Syndrome; Uric Acid	1985
Low plasma selenium as a risk factor for cancer death in middle-aged men. Nutrition and cancer, 1987, Volume: 10, Issue:4 Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; beta 2-Microglobulin; Cholesterol; Humans;	1987
Serum uric acid unrelated to cancer incidence in humans. Cancer research, 1988, May-15, Volume: 48, Issue:10 Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Regression Analysis; Risk Factors; Uric Acid	1988
Metabolic emergencies in pediatric oncology: the acute tumor lysis syndrome. Journal of the Association of Pediatric Oncology Nurses, 1987, Volume: 4, Issue:3-4 Topics: Child; Emergencies; Humans; Hyperkalemia; Hypocalcemia; Metabolic Diseases; Neoplasms; Phosphates; U	1987
[Utility of the uric acid clearance method as a marker of antitumor effect of chemotherapy in cases of malignancies]. Nihon Gan Chiryo Gakkai shi, 1987, Dec-20, Volume: 22, Issue:10 Topics: Adult; Aged; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Uric Acid	1987
beta-Aminoisobutyric acid as a marker of thymine catabolism in malignancy. Clinica chimica acta; international journal of clinical chemistry, 1987, Jun-15, Volume: 165, Issue:2-3 Topics: Adolescent; Aminobutyrates; Child; Child, Preschool; Humans; Infant; Leukocyte Count; Neoplasms; Pur	1987
[Amino acid and protein metabolism in critically ill patients]. Infusionstherapie und klinische Ernahrung, 1985, Volume: 12, Issue:6 Topics: Adult; Aged; Amino Acids; Animals; Blood Proteins; Cholecystectomy; Critical Care; Dogs; Female; Hum	1985
Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193). Cancer research, 1985, Volume: 45, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Aspartate Aminotransferases; Bone Marrow; Creatine Kinase; Drug	1985
Oncologic emergencies I. Metabolic and space-occupying consequences of cancer and cancer treatment. Pediatric clinics of North America, 1985, Volume: 32, Issue:3 Topics: Calcium; Child; Constriction, Pathologic; Emergencies; Humans; Neoplasms; Phosphates; Potassium; Pur	1985
Letter: Allopurinol and bone-marrow depression. Lancet (London, England), 1974, Aug-17, Volume: 2, Issue:7877 Topics: Acute Kidney Injury; Allopurinol; Bone Marrow; Cyclophosphamide; Drug Synergism; Humans; Neoplasms;	1974
[General medical measures in neoplastic diseases and their complications]. Praxis, 1967, Dec-14, Volume: 56, Issue:50 Topics: Anemia; Central Nervous System Diseases; Humans; Hypercalcemia; Hyperinsulinism; Hyperparathyroidism	1967
Letter: Hyperphosphatemia and hypocalcemia in neoplastic disorders. The New England journal of medicine, 1974, Apr-11, Volume: 290, Issue:15 Topics: Aged; Animals; Antineoplastic Agents; Child, Preschool; Cholecalciferol; Humans; Hypocalcemia; Leuke	1974
Relationship between urinary beta-aminoisobutyric acid and transfer RNA turnover in cancer patients. Cancer research, 1974, Volume: 34, Issue:12 Topics: Aged; Aminoisobutyric Acids; Carcinoma, Transitional Cell; Colonic Neoplasms; DNA, Neoplasm; Female;	1974
Preliminary clinical experience with cis-diamminedichloroplatinum (II) (NSC 119875, CACP). Cancer, 1972, Volume: 30, Issue:6 Topics: Amines; Anemia; Antineoplastic Agents; Audiometry; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cel	1972
The clinical significance of hypouricemia. Annals of internal medicine, 1973, Volume: 78, Issue:2 Topics: Allopurinol; Aspirin; Contrast Media; Depression, Chemical; Diet; Female; Guaifenesin; Humans; Liver	1973
Methrotrexate U.S.P. (amethopterin) and methotrexate sodium. American journal of hospital pharmacy, 1973, Volume: 30, Issue:6 Topics: Abortion, Induced; Anemia; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Choriocarcinoma	1973
Causes of hypouricemia. Annals of internal medicine, 1973, Volume: 78, Issue:6 Topics: Adult; Alcoholism; Female; Humans; Liver Diseases; Male; Middle Aged; Neoplasms; Salicylates; Uric A	1973
[Emergencies in oncology]. Schweizerische medizinische Wochenschrift, 1973, Sep-08, Volume: 103, Issue:36 Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Breast Neoplasms; Carcinoma; Emergencies; Estradiol;	1973
Proceedings: Cyclophosphamide and the kidney. Cancer, 1974, Volume: 33, Issue:2 Topics: Adolescent; Adult; Amino Acids; Body Weight; Calcium; Cyclophosphamide; Cystitis; Diuresis; Female;	1974
Pharmacogenetics. American family physician, 1974, Volume: 9, Issue:4 Topics: Abnormalities, Drug-Induced; Allopurinol; Barbiturates; Chromosome Aberrations; Drug-Related Side Ef	1974
The clinical significance of hypouricemia. Advances in experimental medicine and biology, 1974, Volume: 41 Topics: Allopurinol; Amino Acids; Aspirin; Autoanalysis; Creatinine; Glycosuria; Humans; Kidney Diseases; Ne	1974
Synthesis and oncogenicity of 3-hydroxyuric acid. Biochemistry, 1971, Nov-23, Volume: 10, Issue:24 Topics: Animals; Benzyl Compounds; Carbon Isotopes; Carcinogens; Chemical Phenomena; Chemistry; Chromatograp	1971
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Hyperuricaemia in northern Finland. An epidemiological study of serum uric acid in rural, urban and hospital populations. Annals of clinical research, 1969, Volume: 1 Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Body Weight; Cerebrovascular Disorders; Cholesterol; C	1969
Hyperuricemia in neoplastic disease in children: prevention with allopurinol, a xanthine oxidase inhibitor. Pediatrics, 1968, Volume: 41, Issue:1 Topics: Adolescent; Allopurinol; Blood Urea Nitrogen; Child; Child, Preschool; Female; Humans; Leukocyte Cou	1968

uric acid and Neoplasms

Research Excerpts

Research

Studies (161)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Huang, Q	1
Wang, P	1
Liao, X	1
Chen, MM	1
Meng, LH	1
Oriaifo, IA	1
Gerard, JM	1
Thomas, SM	1
Farooqui, N	1
Sy-Go, JPT	1
Miao, J	1
Mehta, R	1
Vaughan, LE	1
Bennani, NN	1
Wang, Y	5
Bansal, R	1
Hathcock, MA	1
Hayman, SR	1
Johnston, PB	1
Villasboas, JC	1
Paludo, J	1
Ansell, SM	1
Leung, N	1
Lin, Y	1
Herrmann, SM	1
Chen, Y	6
Xu, W	2
Han, A	1
Song, J	4
Zhou, X	3
Song, W	2
Chen, YY	3
Kurniawan, D	3
Mousavi, SM	3
Fedotov, PV	3
Obraztsova, ED	3
Chiang, WH	3
Suliman, NA	1
Awadalla, KE	1
Bakheit, KH	1
Mohamed, AO	1
Hu, L	1
Hu, G	1
Xu, BP	1
Zhu, L	1
Zhou, W	1
Wang, T	2
Bao, H	1
Cheng, X	1
Fautrel, B	1
Belhassen, M	1
Hudry, C	1
Woronoff-Lemsi, MC	1
Levy-Bachelot, L	1
Van Ganse, E	1
Tubach, F	1
Nyce, JW	1
Martens, KL	2
Khalighi, PR	2
Li, S	3
White, AA	2
Silgard, E	2
Frieze, D	2
Estey, E	1
Garcia, DA	2
Hingorani, S	1
Li, A	2
Kodar, K	1
McConnell, MJ	1
Harper, JL	2
Timmer, MS	1
Stocker, BL	1
Ameri, P	1
Canepa, M	1
Luigi Nicolosi, G	1
Marchioli, R	1
Latini, R	1
Tavazzi, L	1
Maggioni, AP	1
Nguépy Keubo, FR	1
Mboua, PC	1
Djifack Tadongfack, T	1
Fokouong Tchoffo, E	1
Tasson Tatang, C	1
Ide Zeuna, J	1
Noupoue, EM	1
Tsoplifack, CB	1
Folefack, GO	1
Kettani, M	1
Bandelier, P	1
Huo, J	1
Li, H	4
Yu, D	1
Arulsamy, N	1
AlAbbad, S	1
Sardot, T	1
Lekashvili, O	1
Decato, D	1
Lelj, F	1
Alexander Ross, JB	1
Rosenberg, E	1
Nazir, H	1
Muthuswamy, N	1
Louis, C	1
Jose, S	1
Prakash, J	1
Buan, MEM	1
Flox, C	1
Chavan, S	1
Shi, X	1
Kauranen, P	1
Kallio, T	1
Maia, G	1
Tammeveski, K	1
Lymperopoulos, N	1
Carcadea, E	1
Veziroglu, E	1
Iranzo, A	1
M Kannan, A	1
Arunamata, A	1
Tacy, TA	1
Kache, S	1
Mainwaring, RD	1
Ma, M	1
Maeda, K	1
Punn, R	1
Noguchi, S	1
Hahn, S	3
Iwasa, Y	3
Ling, J	2
Voccio, JP	2
Kim, Y	3
Bascuñán, J	2
Chu, Y	1
Tomita, M	1
Cazorla, M	1
Herrera, E	1
Palomeque, E	1
Saud, N	1
Hoplock, LB	1
Lobchuk, MM	1
Lemoine, J	1
Li, X	10
Henson, MA	1
Unsihuay, D	1
Qiu, J	1
Swaroop, S	1
Nagornov, KO	1
Kozhinov, AN	1
Tsybin, YO	1
Kuang, S	1
Laskin, J	1
Zin, NNINM	1
Mohamad, MN	1
Roslan, K	1
Abdul Wafi, S	1
Abdul Moin, NI	1
Alias, A	1
Zakaria, Y	1
Abu-Bakar, N	1
Naveed, A	1
Jilani, K	1
Siddique, AB	1
Akbar, M	1
Riaz, M	1
Mushtaq, Z	1
Sikandar, M	1
Ilyas, S	1
Bibi, I	1
Asghar, A	1
Rasool, G	1
Irfan, M	1
Li, XY	1
Zhao, S	1
Fan, XH	1
Chen, KP	1
Hua, W	1
Liu, ZM	1
Xue, XD	1
Zhou, B	1
Zhang, S	2
Xing, YL	1
Chen, MA	1
Sun, Y	1
Neradilek, MB	1
Wu, XT	1
Zhang, D	2
Huang, W	1
Cui, Y	1
Yang, QQ	1
Li, HW	1
Zhao, XQ	1
Hossein Rashidi, B	1
Tarafdari, A	1
Ghazimirsaeed, ST	1
Shahrokh Tehraninezhad, E	1
Keikha, F	1
Eslami, B	1
Ghazimirsaeed, SM	1
Jafarabadi, M	1
Silvani, Y	1
Lovita, AND	1
Maharani, A	1
Wiyasa, IWA	1
Sujuti, H	1
Ratnawati, R	1
Raras, TYM	1
Lemin, AS	1
Rahman, MM	1
Pangarah, CA	1
Kiyu, A	1
Zeng, C	2
Du, H	1
Lin, D	1
Jalan, D	1
Rubagumya, F	1
Hopman, WM	1
Vanderpuye, V	1
Lopes, G	1
Seruga, B	1
Booth, CM	1
Berry, S	1
Hammad, N	1
Sajo, EA	1
Okunade, KS	1
Olorunfemi, G	1
Rabiu, KA	1
Anorlu, RI	1
Xu, C	2
Xiang, Y	1
Xu, X	2
Zhou, L	2
Dong, X	1
Tang, S	1
Gao, XC	1
Wei, CH	1
Zhang, RG	1
Cai, Q	1
He, Y	1
Tong, F	1
Dong, JH	1
Wu, G	1
Dong, XR	1
Tang, X	1
Tao, F	1
Xiang, W	1
Zhao, Y	2
Jin, L	1
Tao, H	1
Lei, Y	2
Gan, H	1
Huang, Y	1
Chen, L	3
Shan, A	1
Zhao, H	2
Wu, M	2
Ma, Q	1
Wang, J	4
Zhang, E	1
Zhang, J	3
Li, Y	5
Xue, F	1
Deng, L	1
Liu, L	2
Yan, Z	2
Meng, J	1
Chen, G	2
Anastassiadou, M	1
Bernasconi, G	1
Brancato, A	1
Carrasco Cabrera, L	1
Greco, L	1
Jarrah, S	1
Kazocina, A	1
Leuschner, R	1
Magrans, JO	1
Miron, I	1
Nave, S	1
Pedersen, R	1
Reich, H	1
Rojas, A	1
Sacchi, A	1
Santos, M	1
Theobald, A	1
Vagenende, B	1
Verani, A	1
Du, L	1
Liu, X	1
Ren, Y	1
Li, J	7
Li, P	1
Jiao, Q	1
Meng, P	1
Wang, F	2
Wang, YS	1
Wang, C	3
Wang, W	1
Wang, S	2
Hou, J	1
Zhang, A	1
Lv, B	1
Gao, C	1
Pang, D	1
Lu, K	1
Ahmad, NH	1
Wang, L	1
Zhu, J	2
Zhang, L	3
Zhuang, T	1
Tu, J	1
Zhao, Z	1
Qu, Y	1
Yao, H	1
Wang, X	7
Lee, DF	1
Shen, J	3
Wen, L	1
Huang, G	2
Xie, X	1
Zhao, Q	2
Hu, W	1
Zhang, Y	5
Wu, X	1
Lu, J	2
Li, M	1
Li, W	2
Wu, W	1
Du, F	1
Ji, H	1
Yang, X	2
Xu, Z	1
Wan, L	1
Wen, Q	1
Cho, CH	1
Zou, C	1
Xiao, Z	1
Liao, J	1
Su, X	1
Bi, Z	1
Su, Q	1
Huang, H	1
Wei, Y	3
Gao, Y	2
Na, KJ	1
Choi, H	1
Oh, HR	1
Kim, YH	1
Lee, SB	1
Jung, YJ	1
Koh, J	1
Park, S	1
Lee, HJ	1
Jeon, YK	1
Chung, DH	1
Paeng, JC	1
Park, IK	1
Kang, CH	1
Cheon, GJ	1
Kang, KW	1
Lee, DS	1
Kim, YT	1
Pajuelo-Lozano, N	1
Alcalá, S	1
Sainz, B	1
Perona, R	1
Sanchez-Perez, I	1
Logotheti, S	1
Marquardt, S	1
Gupta, SK	1
Richter, C	1
Edelhäuser, BAH	1
Engelmann, D	1
Brenmoehl, J	1
Söhnchen, C	1
Murr, N	1
Alpers, M	1
Singh, KP	1
Wolkenhauer, O	1
Heckl, D	1
Spitschak, A	1
Pützer, BM	1
Liao, Y	1
Cheng, J	1
Kong, X	1
Zhang, M	4
Zhang, H	1
Yang, T	2
Dong, Y	1
Xu, Y	1
Yuan, Z	1
Cao, J	1
Zheng, Y	1
Luo, Z	1
Mei, Z	1
Yao, Y	1
Liu, Z	2
Liang, C	1
Yang, H	1
Song, Y	1
Yu, K	1
Zhu, C	1
Huang, Z	1
Qian, J	1
Ge, J	1
Hu, J	2
Wang, H	2
Liu, Y	5
Mi, Y	1
Kong, H	1
Xi, D	1
Yan, W	1
Luo, X	1
Ning, Q	1
Chang, X	2
Zhang, T	2
Wang, Q	2
Rathore, MG	1
Reddy, K	1
Chen, H	1
Shin, SH	1
Ma, WY	1
Bode, AM	1
Dong, Z	1
Mu, W	1
Liu, C	3
Gao, F	1
Qi, Y	1
Lu, H	1
Zhang, X	5
Cai, X	1
Ji, RY	1
Hou, Y	3
Tian, J	2
Shi, Y	1
Ying, S	1
Tan, M	1
Feng, G	1
Kuang, Y	1
Chen, D	1
Wu, D	3
Zhu, ZQ	1
Tang, HX	1
Shi, ZE	1
Kang, J	1
Liu, Q	1
Qi, J	2
Mu, J	1
Cong, Z	1
Chen, S	2
Fu, D	1
Li, Z	2
Celestrin, CP	1
Rocha, GZ	1
Stein, AM	1
Guadagnini, D	1
Tadelle, RM	1
Saad, MJA	1
Oliveira, AG	1
Bianconi, V	1
Bronzo, P	1
Banach, M	1
Sahebkar, A	1
Mannarino, MR	1
Pirro, M	1
Patsourakos, NG	1
Kouvari, M	1
Kotidis, A	1
Kalantzi, KI	1
Tsoumani, ME	1
Anastasiadis, F	1
Andronikos, P	1
Aslanidou, T	1
Efraimidis, P	1
Georgiopoulos, A	1
Gerakiou, K	1
Grigoriadou-Skouta, E	1
Grigoropoulos, P	1
Hatzopoulos, D	1
Kartalis, A	1
Lyras, A	1
Markatos, G	1
Mikrogeorgiou, A	1
Myroforou, I	1
Orkopoulos, A	1
Pavlidis, P	1
Petras, C	1
Riga, M	1
Skouloudi, M	1
Smyrnioudis, N	1
Thomaidis, K	1
Tsikouri, GE	1
Tsikouris, EI	1
Zisimos, K	1
Vavoulis, P	1
Vitali, MG	1
Vitsas, G	1
Vogiatzidis, C	1
Chantanis, S	1
Fousas, S	1
Panagiotakos, DB	1
Tselepis, AD	1
Jungen, C	1
Alken, FA	1
Eickholt, C	1
Scherschel, K	1
Kuklik, P	1
Klatt, N	1
Schwarzl, J	1
Moser, J	1
Jularic, M	1
Akbulak, RO	1
Schaeffer, B	1
Willems, S	1
Meyer, C	1
Nowak, JK	1
Szczepanik, M	1
Trypuć, M	1
Pogorzelski, A	1
Bobkowski, W	1
Grytczuk, M	1
Minarowska, A	1
Wójciak, R	1
Walkowiak, J	1
Lu, Y	1
Xi, J	1
Li, C	1
Chen, W	2
Hu, X	1
Zhang, F	1
Wei, H	1
Wang, Z	1
Gurzu, S	1
Jung, I	1
Sugimura, H	2
Stefan-van Staden, RI	1
Yamada, H	1
Natsume, H	1
Iwashita, Y	1
Szodorai, R	1
Szederjesi, J	1
Yari, D	1
Ehsanbakhsh, Z	1
Validad, MH	1
Langroudi, FH	1
Esfandiari, H	1
Prager, A	1
Hassanpour, K	1
Kurup, SP	1
Mets-Halgrimson, R	1
Yoon, H	1
Zeid, JL	1
Mets, MB	1
Rahmani, B	1
Araujo-Castillo, RV	1
Culquichicón, C	1
Solis Condor, R	1
Efendi, F	1
Sebayang, SK	1
Astutik, E	1
Hadisuyatmana, S	1
Has, EMM	1
Kuswanto, H	1
Foroutan, T	1
Ahmadi, F	1
Moayer, F	1
Khalvati, S	1
Zhang, Q	2
Lyu, Y	1
Huang, J	1
Yu, N	1
Wen, Z	1
Hou, H	1
Zhao, T	1
Gupta, A	1
Khosla, N	1
Govindasamy, V	1
Saini, A	1
Annapurna, K	1
Dhakate, SR	1
Akkaya, Ö	1
Chandgude, AL	1
Dömling, A	1
Harnett, J	1
Oakes, K	1
Carè, J	1
Leach, M	1
Brown, D	1
Cramer, H	1
Pinder, TA	1
Steel, A	1
Anheyer, D	1
Cantu, J	1
Valle, J	1
Flores, K	1
Gonzalez, D	1
Valdes, C	1
Lopez, J	1
Padilla, V	1
Alcoutlabi, M	1
Parsons, J	1
Núñez, K	1
Hamed, M	1
Fort, D	1
Bruce, D	1
Thevenot, P	1
Cohen, A	1
Weber, P	1
Menezes, AMB	1
Gonçalves, H	1
Perez-Padilla, R	1
Jarvis, D	1
de Oliveira, PD	1
Wehrmeister, FC	1
Mir, S	1
Wong, J	1
Ryan, CM	1
Bellingham, G	1
Singh, M	2
Waseem, R	1
Eckert, DJ	1
Chung, F	1
Hegde, H	1
Shimpi, N	1
Panny, A	1
Glurich, I	1
Christie, P	1
Acharya, A	1
English, KL	1
Downs, M	1
Goetchius, E	1
Buxton, R	1
Ryder, JW	1
Ploutz-Snyder, R	1
Guilliams, M	1
Scott, JM	1
Ploutz-Snyder, LL	1
Martens, C	1
Goplen, FK	1
Aasen, T	1
Gjestad, R	1
Nordfalk, KF	1
Nordahl, SHG	1
Inoue, T	1
Soshi, S	1
Kubota, M	1
Marumo, K	1
Mortensen, NP	1
Caffaro, MM	1
Patel, PR	2
Uddin, MJ	1
Aravamudhan, S	1
Sumner, SJ	1
Fennell, TR	1
Gal, RL	1
Cohen, NJ	1
Kruger, D	1
Beck, RW	1
Bergenstal, RM	1
Calhoun, P	1
Cushman, T	1
Haban, A	1
Hood, K	1
Johnson, ML	1
McArthur, T	1
Olson, BA	1
Weinstock, RS	1
Oser, SM	1
Oser, TK	1
Bugielski, B	1
Strayer, H	1
Aleppo, G	1
Maruyama, H	1
Hirayama, K	1
Yamashita, M	1
Ohgi, K	1
Tsujimoto, R	1
Takayasu, M	1
Shimohata, H	1
Kobayashi, M	1
Buscagan, TM	1
Rees, DC	1
Jaborek, JR	1
Zerby, HN	1
Wick, MP	1
Fluharty, FL	1
Moeller, SJ	1
Razavi, P	1
Dickler, MN	1
Shah, PD	1
Toy, W	1
Brown, DN	1
Won, HH	1
Li, BT	1
Shen, R	1
Vasan, N	1
Modi, S	1
Jhaveri, K	1
Caravella, BA	1
Patil, S	1
Selenica, P	1
Zamora, S	1
Cowan, AM	1
Comen, E	1
Singh, A	1
Covey, A	1
Berger, MF	1
Hudis, CA	1
Norton, L	1
Nagy, RJ	1
Odegaard, JI	1
Lanman, RB	1
Solit, DB	1
Robson, ME	1
Lacouture, ME	1
Brogi, E	1
Reis-Filho, JS	1
Moynahan, ME	1
Scaltriti, M	1
Chandarlapaty, S	1
Papouskova, K	1
Moravcova, M	1
Masrati, G	1
Ben-Tal, N	1
Sychrova, H	1
Zimmermannova, O	1
Fang, J	1
Fan, Y	1
Luo, T	2
Su, H	1
Tsetseris, L	1
Anthopoulos, TD	1
Liu, SF	1
Zhao, K	1
Sacan, O	1
Turkyilmaz, IB	1
Bayrak, BB	1
Mutlu, O	1
Akev, N	1
Yanardag, R	1
Gruber, S	1
Kamnoedboon, P	1
Özcan, M	1
Srinivasan, M	1
Jo, YH	1
Oh, HK	1
Jeong, SY	1
Lee, BG	1
Zheng, J	1
Guan, H	1
Li, D	2
Tan, H	1
Maji, TK	1
J R, A	1
Mukherjee, S	1
Alexander, R	1
Mondal, A	1
Das, S	1
Sharma, RK	1
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Pessina, AC	2
Tikhonoff, V	1
Smalley, RV	1
Guaspari, A	1
Haase-Statz, S	1
Anderson, SA	1
Cederberg, D	1
Hohneker, JA	1
Pui, CH	1
Jeha, S	1
Irwin, D	1
Camitta, B	1
Carducci, MA	1
Gilbert, J	1
Bowling, MK	1
Noe, D	1
Eisenberger, MA	1
Sinibaldi, V	1
Zabelina, Y	1
Chen, TL	1
Grochow, LB	1
Donehower, RC	1
Abiaka, C	1
Al-Awadi, F	1
Al-Sayer, H	1
Gulshan, S	1
Behbehani, A	1
Farghally, M	1
Simbeye, A	1
Fuchs, D	1
Hermann, J	1
Zintl, F	1
Plenert, W	1
Garnick, MB	1
Mayer, RJ	1
Murphy, TF	1
Mertz, DP	1
Hohneck, A	1
Stolinsky, DC	1
Godin, M	1
Putterman, GJ	1
Shaikh, B	1
Hallmark, MR	1
Sawyer, CG	1
Hixson, CV	1
Perini, F	1
Senn, HJ	1
Chernow, B	1
Wallner, SF	1
Ohnuma, T	1
Roboz, J	1
Shapiro, ML	1
Holland, JF	1
Wiktor-Jedrzejczak, W	1
Siekierzynski, M	1
Piechota, W	1
Razis, DV	1
Athanasiou, A	1
Dadiotis, L	1
Dil'man, VM	1
Bershteĭn, LM	1
Tsyrlina, EV	1
Bobrov, IuF	1
Kovaleva, IG	1
Seigel, DG	1
Cannell, PK	1
Herrmann, RP	1
Criqui, MH	1
Bangdiwala, S	1
Goodman, DS	1
Blaner, WS	1
Morris, JS	1
Kritchevsky, S	1
Lippel, K	1
Mebane, I	1
Tyroler, HA	1
Greenwald, P	1
Ogino, K	1
Hisatome, I	1
Saitoh, M	1
Miyamoto, J	1
Ishiko, R	1
Hasegawa, J	1
Kotake, H	1
Mashiba, H	1
Thomas, CR	1
Dodhia, N	1
Dimaggio, JJ	1
Warrell, RP	1
Muindi, J	1
Stevens, YW	1
Lee, SJ	1
Lowenthal, DA	1
Haines, I	1
Walsh, TD	1
Baltzer, L	1
Yaldaei, S	1
Smith, BN	1
Dai, R	1
Levine, W	1
Dyer, AR	1
Shekelle, RB	1
Schoenberger, JA	1
Stamler, J	1
Lickl, E	1
Alth, G	1
Ebermann, R	1
Beck, RH	1
Tuma, K	1
Leclercq, B	1
Escudier, B	1
Nitenberg, G	1
Fex, G	1
Pettersson, B	1
Akesson, B	1
Hiatt, RA	1
Fireman, BH	1
Patterson, KL	1
Klopovich, P	1
Kagawa, D	1
Ando, S	1
Uchida, M	1
Nakamura, T	1
Domae, N	1
Uchino, H	1
van Gennip, AH	1
van Bree-Blom, EJ	1
Abeling, NG	1
van Erven, AJ	1
Voûte, PA	1
Ishida, N	1
Roth, E	1
Melink, TJ	1
Von Hoff, DD	1
Kuhn, JG	1
Hersh, MR	1
Sternson, LA	1
Patton, TF	1
Siegler, R	1
Boldt, DH	1
Clark, GM	1
Allegretta, GJ	1
Weisman, SJ	1
Altman, AJ	1
Shapiro, S	1
Sonntag, RW	1
Nielsen, HR	1
Nyholm, K	1
Sjolin, KE	1
Greenwald, ES	1
Rossof, AH	1
Slayton, RE	1
Perlia, CP	1
Ramsdell, CM	2
Kelley, WN	2
Van Peenen, HJ	1
Nagel, GA	1
Köberle, S	1
Schmid, I	1
Mayr, AC	1
Obrecht, JP	1
DeFronzo, RA	1
Colvin, OM	1
Braine, H	1
Robertson, GL	1
Davis, PJ	1
Dipalma, JR	1
Gutman, AB	1
Vogler, WR	1
Hitchings, GH	1
Lee, TC	1
Stöhrer, G	1
Teller, MN	1
Myles, A	1
Brown, GB	1
Hiraki, K	1
Kimura, I	1
Asano, K	1
Karvanishi, K	1
Sezaki, T	1
Isomäki, H	1
Murphy, ML	1