uric acid has been researched along with Neoplasms in 161 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Excerpt | Relevance | Reference |
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"Control of serum uric acid (sUA) levels is very important during chemotherapy in patients with malignant tumors, as the risks of tumor lysis syndrome (TLS) and renal events are increased with increasing levels of sUA." | 9.22 | Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. ( Fujimaki, K; Fujisaki, T; Gemba, K; Goto, T; Kaneko, M; Kawai, Y; Kiguchi, T; Kirito, K; Maemondo, M; Nakajima, A; Okamoto, M; Takeda, K; Tamura, K; Ueda, T, 2016) |
"While rasburicase has shown efficacy to rapidly correct hyperuricemia compared with allopurinol, its overall impact in improving clinically significant outcomes, such as acute kidney injury (AKI), in tumor lysis syndrome (TLS) is unknown." | 7.96 | Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. ( Estey, E; Frieze, D; Garcia, DA; Hingorani, S; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020) |
"The levels of CA 125 in mild and severe preeclampsia were (21." | 5.91 | Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023) |
"Uric acid is a powerful antioxidant and is a scavenger of singlet oxygen and radicals." | 5.26 | Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. ( Ames, BN; Cathcart, R; Hochstein, P; Schwiers, E, 1981) |
"Control of serum uric acid (sUA) levels is very important during chemotherapy in patients with malignant tumors, as the risks of tumor lysis syndrome (TLS) and renal events are increased with increasing levels of sUA." | 5.22 | Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. ( Fujimaki, K; Fujisaki, T; Gemba, K; Goto, T; Kaneko, M; Kawai, Y; Kiguchi, T; Kirito, K; Maemondo, M; Nakajima, A; Okamoto, M; Takeda, K; Tamura, K; Ueda, T, 2016) |
"Although urate oxidase might be effective in reducing serum uric acid, it is unclear whether it reduces clinical tumour lysis syndrome, renal failure, or mortality." | 4.90 | Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. ( Chan, GC; Cheuk, DK; Chiang, AK; Ha, SY, 2014) |
" However, ARF may also develop due to aetiologies arising from cancer treatment or the disease itself, including: nephrotoxic chemotherapy agents, post-renal obstruction, compression and infiltration by malignancy, tumour lysis syndrome, uric acid, sepsis and contrast agent nephropathy." | 4.82 | Acute renal failure in cancer patients. ( Flombaum, CD; Lameire, NH; Moreau, D; Ronco, C, 2005) |
" Adherence to guidelines has not been well studied, and the correlation between uric acid reduction and clinically relevant outcomes, such as acute kidney injury, remains unclear." | 3.96 | Utilization patterns and clinical outcomes of rasburicase administration according to tumor risk stratification. ( Frieze, D; Garcia, DA; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020) |
"In addition to the controversy regarding the association of hyperuricemia with mortality, uncertainty also remains regarding the association between low serum uric acid (SUA) and mortality." | 3.96 | U-Shaped Association of Serum Uric Acid With All-Cause and Cause-Specific Mortality in US Adults: A Cohort Study. ( Bao, H; Cheng, X; Hu, G; Hu, L; Wang, T; Xu, BP; Zhou, W; Zhu, L, 2020) |
"While rasburicase has shown efficacy to rapidly correct hyperuricemia compared with allopurinol, its overall impact in improving clinically significant outcomes, such as acute kidney injury (AKI), in tumor lysis syndrome (TLS) is unknown." | 3.96 | Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. ( Estey, E; Frieze, D; Garcia, DA; Hingorani, S; Khalighi, PR; Li, A; Li, S; Martens, KL; Silgard, E; White, AA, 2020) |
"Rasburicase is indicated for the initial management of plasma uric acid levels in adults receiving anticancer therapy who are at risk for acute tumor lysis syndrome (TLS) and subsequent hyperuricemia." | 3.76 | Fixed-dose rasburicase 6 mg for hyperuricemia and tumor lysis syndrome in high-risk cancer patients. ( Shanholtz, CB; Thompson, JL; Vines, AN, 2010) |
" The vast majority of these patients had a malignancy and were in danger of developing tumor lysis syndrome (TLS) and subsequent acute uric acid nephropathy (AUAN) and were unable to take oral allopurinol." | 3.70 | Allopurinol: intravenous use for prevention and treatment of hyperuricemia. ( Anderson, SA; Cederberg, D; Guaspari, A; Haase-Statz, S; Hohneker, JA; Smalley, RV, 2000) |
"The relationships of serum uric acid to mortality from all causes, the cardiovascular diseases, and cancer were evaluated in 6797 white women age 35-64 years followed for an average of 11." | 3.67 | Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry. ( Dyer, AR; Levine, W; Schoenberger, JA; Shekelle, RB; Stamler, J, 1989) |
"The relative risk of all cancers for high versus low SUA level was 1." | 2.58 | Serum uric acid and cancer mortality and incidence: a systematic review and meta-analysis. ( Boffetta, P; Dovell, F, 2018) |
"Individuals with cancer are subject to fluid and electrolyte imbalances because of the original disease process, therapy, and complications resulting from both the disease process and from therapy." | 2.36 | Fluid and electrolyte disturbances associated with cancer and its treatment. ( Cunningham, SG, 1982) |
"In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death." | 2.36 | Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980) |
"Malignant neoplasms may cause life-threatening complications requiring prompt diagnosis and emergency therapy." | 2.36 | Emergencies in oncology. Current management. ( Stolinsky, DC, 1978) |
"The levels of CA 125 in mild and severe preeclampsia were (21." | 1.91 | Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan. ( Awadalla, KE; Bakheit, KH; Mohamed, AO; Suliman, NA, 2023) |
"Rapid and accurate detection of cancer and neurological diseases is a major issue that has received great attention recently to enable early therapy treatment." | 1.72 | Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers. ( Chen, YY; Chiang, WH; Fedotov, PV; Kurniawan, D; Mousavi, SM; Obraztsova, ED, 2022) |
"During the follow-up period, 1619 cancer diagnoses and 617 cancer-related deaths were recorded." | 1.62 | Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population. ( Choi, CK; Choi, SW; Kim, HY; Kim, YR; Kweon, SS; Lee, YH; Shin, MH, 2021) |
"Patients with cancer were older and more often former smokers, had lower body mass index, lower left ventricular ejection fraction (LVEF), less implanted devices, lower glucose and haemoglobin and higher uric acid levels than those without cancer." | 1.56 | Cancer in chronic heart failure patients in the GISSI-HF trial. ( Ameri, P; Canepa, M; Latini, R; Luigi Nicolosi, G; Maggioni, AP; Marchioli, R; Tavazzi, L, 2020) |
"Using data from The Cancer Genome Atlas (TCGA), we analysed the expression levels of xanthine dehydrogenase (XDH) and adenine phosphoribosyltransferase (APRT), two key enzymes in UA production and the purine salvage pathway, respectively." | 1.48 | A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates. ( Ceballos-Picot, I; Chatelain, D; Chauffert, B; Dahmani, S; Galmiche, A; Guedda, S; Louandre, C; Saidak, Z; Sauzay, C, 2018) |
"A total of 232 participants developed cancer." | 1.46 | Association of serum uric acid with increased risk of cancer among hypertensive Chinese. ( Gao, W; Gu, J; Hou, FF; Huo, Y; Jiang, H; Jiang, X; Lei, Y; Qin, X; Shen, L; Wang, B; Wang, X; Wang, Y; Xu, X; Yang, J; Zhang, R; Zhang, X; Zhao, Q, 2017) |
"Hazard ratio (HR) for overall cancer for the 4th quartile of uric acid compared to the 1st was 1." | 1.46 | Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study. ( Garmo, H; Hammar, N; Holmberg, L; Jungner, I; Lambe, M; Malmström, H; Van Hemelrijck, M; Walldius, G; Wulaningsih, W; Yiu, A, 2017) |
"A total of 8274 patients with type 2 diabetes from the Shanghai Diabetes Registry (SDR) participated." | 1.43 | Association between uric acid, cancer incidence and mortality in patients with type 2 diabetes: Shanghai diabetes registry study. ( Bao, Y; Deng, Z; Gu, Y; Hou, X; Hu, C; Jia, W; Zhang, L, 2016) |
"We analyzed the association between cancer mortality risk and SUA level both as continuous variable and as tertiles: lowest <5 mg/dl (reference), middle 5-5." | 1.40 | Serum uric acid levels and cancer mortality risk among males in a large general population-based cohort study. ( Boezen, HM; Taghizadeh, N; Vonk, JM, 2014) |
"A perspective adsorptive method to minimize systemic toxic effects of chemotherapy is enterosorption (ES)." | 1.39 | Enterosorption as a method to decrease the systemic toxicity of cisplatin. ( Bardakhivskaya, KI; Ivanyuk, AA; Korotich, VG; Maslenniy, VN; Nikolaev, VG; Nikolaeva, VV; Sakhno, LA; Shevchuk, OO; Yurchenko, OV, 2013) |
"Cachexia is a common co-morbidity in cancer occurring in up to 80% of patients depending on the type of cancer." | 1.38 | Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. ( Adams, V; Anker, SD; Argiles, JM; Doehner, W; Hartman, K; Köhrle, J; Möller, N; Palus, S; Ruis, SB; Springer, J; Tschirner, A; von Haehling, S; Wirth, EK, 2012) |
"Risk of cancer is increased in conditions associated with insulin resistance, but this could be secondary to subclinical inflammation." | 1.36 | Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. ( Godsland, IF; Johnston, DG; Loh, WJ; North, BV, 2010) |
"Uric acid (UA) is an endogenous danger signal recently identified to be released from dying cells." | 1.35 | The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity. ( Behrens, MD; Disis, ML; Erskine, CL; Gad, EA; Kalli, KR; Knutson, KL; Krco, CJ; Krempski, J; Wagner, WM, 2008) |
" The drug dosing was calculated based on the patients' ideal body weight (IBW) or adjusted body weight (aBW) for those who were more than 30% above their IBW." | 1.35 | Single-dose rasburicase for tumour lysis syndrome in adults: weight-based approach. ( Campara, M; Haaf, CM; Shord, SS, 2009) |
"During follow-up 5189 incident cancers were observed." | 1.35 | Use of penalized splines in extended Cox-type additive hazard regression to flexibly estimate the effect of time-varying serum uric acid on risk of cancer incidence: a prospective, population-based study in 78,850 men. ( Brant, LJ; Concin, H; Diem, G; Hilbe, W; Kaltenbach, L; Klenk, J; Kneib, T; Lang, S; Oberaigner, W; Pfeiffer, KP; Ruttmann, E; Strasak, AM; Ulmer, H, 2009) |
"71 mg/dl) was independently associated with increased risk of mortality from all cancers, showing a clear dose-response relationship (p for trend < 0." | 1.34 | Serum uric acid and risk of cancer mortality in a large prospective male cohort. ( Concin, H; Diem, G; Hilbe, W; Oberaigner, W; Pfeiffer, KP; Rapp, K; Ruttmann, E; Strasak, AM; Ulmer, H, 2007) |
"Thus, cancer cells can no longer divide and cancer activity is inhibited." | 1.34 | Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im ( Chen, Y; Duvvi, H; Lu, DP; Ohki, M; Omura, Y; Shimotsura, Y, 2007) |
"One hundred eighteen terminally ill cancer patients, including 63 (53." | 1.33 | Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients. ( Cho, KH; Lee, DC; Lee, HR; Shim, JY; Shin, HS; Suh, SY, 2006) |
"The data suggest cancer-related diminished synthesis of cholesterol and, generally, a greater antioxidant burden for alpha-tocopherol than urate in cancer-generated oxidative stress." | 1.31 | Serum antioxidant and cholesterol levels in patients with different types of cancer. ( Abiaka, C; Al-Awadi, F; Al-Sayer, H; Behbehani, A; Farghally, M; Gulshan, S; Simbeye, A, 2001) |
"We analyzed cancer mortality trends in 3282 elderly subjects from two general Italian populations with different life-style patterns taking part in the Cardiovascular Study in the Elderly (CASTEL)." | 1.30 | Cancer mortality trends in two cohorts of elderly people having different life-styles. ( Biasin, R; Casiglia, E; Mazza, A; Pessina, AC; Pizziol, A; Privato, G; Scarpa, R; Sica, E, 1999) |
"RR of cancer mortality increased with increasing ALT or ALP." | 1.30 | Predictors of cancer mortality in elderly subjects. ( Casiglia, E; Mazza, A; Pessina, AC; Pizziol, A; Scarpa, R; Sica, E; Tikhonoff, V, 1999) |
"Fifty patients with advanced cancer were treated at dose levels that ranged from 100 to 1500 mg/m2/day." | 1.28 | Phase I clinical and pharmacological study of merbarone. ( Baltzer, L; Dimaggio, JJ; Haines, I; Lee, SJ; Lowenthal, DA; Muindi, J; Stevens, YW; Walsh, TD; Warrell, RP; Yaldaei, S, 1990) |
"Blood uric acid was measured in 316 cancer patients, 173 men and 143 women and was found higher in all patients than in normal subjects." | 1.28 | [Cancer and hyperuricemia--an analysis of 316 cancer patients]. ( Dai, R, 1989) |
"When the deaths from cancer were classified as "early" or "late"--that is, occurring less than or more than 2." | 1.27 | Raised serum urate concentration as risk factor for premature mortality in middle aged men: relation to death from cancer. ( Petersson, B; Trell, E, 1983) |
"Total cancer incidence as well as site-specific incidence (for lung, colon, and prostate cancer in men and lung, colon, breast, uterine, and cervical cancer in women) was ascertained from hospital discharge records and the Surveillance, Epidemiology and End Results program in the San Francisco-Oakland Bay area." | 1.27 | Serum uric acid unrelated to cancer incidence in humans. ( Fireman, BH; Hiatt, RA, 1988) |
"Uric acid was used as an indicator for tissue-breakdown." | 1.27 | beta-Aminoisobutyric acid as a marker of thymine catabolism in malignancy. ( Abeling, NG; van Bree-Blom, EJ; van Erven, AJ; van Gennip, AH; Voûte, PA, 1987) |
"Patients with sepsis or acute pancreatitis had drastically reduced levels of total muscular free AA, mainly due to a fall in muscle glutamine." | 1.27 | [Amino acid and protein metabolism in critically ill patients]. ( Roth, E, 1985) |
"Tiazofurin levels were measured using a high-pressure liquid chromatography assay, and pharmacokinetic studies were performed in patients treated at each dose level." | 1.27 | Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193). ( Boldt, DH; Clark, GM; Hersh, MR; Kuhn, JG; Melink, TJ; Patton, TF; Siegler, R; Sternson, LA; Von Hoff, DD, 1985) |
"Uric acid is a powerful antioxidant and is a scavenger of singlet oxygen and radicals." | 1.26 | Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. ( Ames, BN; Cathcart, R; Hochstein, P; Schwiers, E, 1981) |
"Post-operative care of cancer patients has to take into consideration additional diseases not related to the basic disease, too." | 1.26 | [Secondary diseases complicating cancer]. ( Kirsch, JJ; Müller, J; Pitule-Schödel, H, 1981) |
"Sixty-six patients with metastatic cancer whose bone marrow biopsies were negative, served as controls." | 1.26 | Variables predictive of bone marrow metastasis. ( Chernow, B; Wallner, SF, 1978) |
"Forty patients with generalized cancer complicated by water and electrolyte retention were treated with "medium" and "large" doses of furosemide and bumetanide with 35% and 40% objective positive response, respectively." | 1.26 | Diuretics in malignant effusions and edemas of generalized cancer. ( Athanasiou, A; Dadiotis, L; Razis, DV, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 73 (45.34) | 18.7374 |
1990's | 15 (9.32) | 18.2507 |
2000's | 22 (13.66) | 29.6817 |
2010's | 31 (19.25) | 24.3611 |
2020's | 20 (12.42) | 2.80 |
Authors | Studies |
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Huang, Q | 1 |
Wang, P | 1 |
Liao, X | 1 |
Chen, MM | 1 |
Meng, LH | 1 |
Oriaifo, IA | 1 |
Gerard, JM | 1 |
Thomas, SM | 1 |
Farooqui, N | 1 |
Sy-Go, JPT | 1 |
Miao, J | 1 |
Mehta, R | 1 |
Vaughan, LE | 1 |
Bennani, NN | 1 |
Wang, Y | 5 |
Bansal, R | 1 |
Hathcock, MA | 1 |
Hayman, SR | 1 |
Johnston, PB | 1 |
Villasboas, JC | 1 |
Paludo, J | 1 |
Ansell, SM | 1 |
Leung, N | 1 |
Lin, Y | 1 |
Herrmann, SM | 1 |
Chen, Y | 6 |
Xu, W | 2 |
Han, A | 1 |
Song, J | 4 |
Zhou, X | 3 |
Song, W | 2 |
Chen, YY | 3 |
Kurniawan, D | 3 |
Mousavi, SM | 3 |
Fedotov, PV | 3 |
Obraztsova, ED | 3 |
Chiang, WH | 3 |
Suliman, NA | 1 |
Awadalla, KE | 1 |
Bakheit, KH | 1 |
Mohamed, AO | 1 |
Hu, L | 1 |
Hu, G | 1 |
Xu, BP | 1 |
Zhu, L | 1 |
Zhou, W | 1 |
Wang, T | 2 |
Bao, H | 1 |
Cheng, X | 1 |
Fautrel, B | 1 |
Belhassen, M | 1 |
Hudry, C | 1 |
Woronoff-Lemsi, MC | 1 |
Levy-Bachelot, L | 1 |
Van Ganse, E | 1 |
Tubach, F | 1 |
Nyce, JW | 1 |
Martens, KL | 2 |
Khalighi, PR | 2 |
Li, S | 3 |
White, AA | 2 |
Silgard, E | 2 |
Frieze, D | 2 |
Estey, E | 1 |
Garcia, DA | 2 |
Hingorani, S | 1 |
Li, A | 2 |
Kodar, K | 1 |
McConnell, MJ | 1 |
Harper, JL | 2 |
Timmer, MS | 1 |
Stocker, BL | 1 |
Ameri, P | 1 |
Canepa, M | 1 |
Luigi Nicolosi, G | 1 |
Marchioli, R | 1 |
Latini, R | 1 |
Tavazzi, L | 1 |
Maggioni, AP | 1 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 4 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 10 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Zhang, S | 2 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 1 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 2 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
Wiyasa, IWA | 1 |
Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
Rahman, MM | 1 |
Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
Jalan, D | 1 |
Rubagumya, F | 1 |
Hopman, WM | 1 |
Vanderpuye, V | 1 |
Lopes, G | 1 |
Seruga, B | 1 |
Booth, CM | 1 |
Berry, S | 1 |
Hammad, N | 1 |
Sajo, EA | 1 |
Okunade, KS | 1 |
Olorunfemi, G | 1 |
Rabiu, KA | 1 |
Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 2 |
Zhou, L | 2 |
Dong, X | 1 |
Tang, S | 1 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 2 |
Gan, H | 1 |
Huang, Y | 1 |
Chen, L | 3 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Wang, J | 4 |
Zhang, E | 1 |
Zhang, J | 3 |
Li, Y | 5 |
Xue, F | 1 |
Deng, L | 1 |
Liu, L | 2 |
Yan, Z | 2 |
Meng, J | 1 |
Chen, G | 2 |
Anastassiadou, M | 1 |
Bernasconi, G | 1 |
Brancato, A | 1 |
Carrasco Cabrera, L | 1 |
Greco, L | 1 |
Jarrah, S | 1 |
Kazocina, A | 1 |
Leuschner, R | 1 |
Magrans, JO | 1 |
Miron, I | 1 |
Nave, S | 1 |
Pedersen, R | 1 |
Reich, H | 1 |
Rojas, A | 1 |
Sacchi, A | 1 |
Santos, M | 1 |
Theobald, A | 1 |
Vagenende, B | 1 |
Verani, A | 1 |
Du, L | 1 |
Liu, X | 1 |
Ren, Y | 1 |
Li, J | 7 |
Li, P | 1 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 2 |
Wang, YS | 1 |
Wang, C | 3 |
Wang, W | 1 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 1 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 1 |
Zhu, J | 2 |
Zhang, L | 3 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Wang, X | 7 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 2 |
Xie, X | 1 |
Zhao, Q | 2 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00187005] | Phase 3 | 53 participants (Actual) | Interventional | 1998-07-31 | Terminated (stopped due to Toxicity) | ||
[NCT00005140] | 0 participants | Observational | 1977-09-30 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
26 reviews available for uric acid and Neoplasms
Article | Year |
---|---|
The double faced role of xanthine oxidoreductase in cancer.
Topics: Humans; Hyperuricemia; Neoplasms; Reactive Oxygen Species; Uric Acid; Xanthine Dehydrogenase | 2022 |
A lex naturalis delineates components of a human-specific, adrenal androgen-dependent, p53-mediated 'kill switch' tumor suppression mechanism.
Topics: Androgens; Biological Evolution; Body Size; Dehydroepiandrosterone Sulfate; Glucosephosphate Dehydro | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Serum uric acid and cancer mortality and incidence: a systematic review and meta-analysis.
Topics: Biomarkers, Tumor; Humans; Incidence; Neoplasms; Prognosis; United States; Uric Acid | 2018 |
Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer.
Topics: Adolescent; Allopurinol; Antimetabolites; Area Under Curve; Child; Controlled Clinical Trials as Top | 2014 |
Serum Uric Acid Increases Risk of Cancer Incidence and Mortality: A Systematic Review and Meta-Analysis.
Topics: Antioxidants; Data Collection; Data Interpretation, Statistical; Female; Humans; Incidence; Male; Ne | 2015 |
Xanthine oxidoreductase in cancer: more than a differentiation marker.
Topics: Animals; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Prognosis; Reactive Nitrogen Spe | 2016 |
Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer.
Topics: Adolescent; Allopurinol; Antimetabolites; Area Under Curve; Child; Controlled Clinical Trials as Top | 2017 |
Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer.
Topics: Allopurinol; Antimetabolites; Child; Controlled Clinical Trials as Topic; Humans; Neoplasms; Randomi | 2010 |
Nanomaterial-based functional scaffolds for amperometric sensing of bioanalytes.
Topics: Animals; Biosensing Techniques; Blood Glucose; Cholesterol; Electrochemical Techniques; Equipment De | 2013 |
[Secondary hypouricemia in patients with malignant disease].
Topics: Acute Disease; Humans; Kidney; Leukemia; Lymphoma; Multiple Myeloma; Neoplasms; Neural Tube Defects; | 2003 |
RENAL COMPLICATIONS OF NEOPLASTIC DISEASE.
Topics: Antineoplastic Agents; Bence Jones Protein; Hemorrhage; Humans; Hypercalcemia; Hypokalemia; Hyponatr | 1963 |
[Prophylaxis and differential therapy of tumorlysis syndrome].
Topics: Allopurinol; Antimetabolites; Antineoplastic Agents; Cost-Benefit Analysis; Enzyme Inhibitors; Human | 2004 |
Acute renal failure in cancer patients.
Topics: Acute Kidney Injury; Antineoplastic Agents; Humans; Hyperuricemia; Neoplasms; Prognosis; Risk Factor | 2005 |
Tumor lysis syndrome.
Topics: Biomarkers; Humans; Kidney Diseases; Neoplasms; Tumor Lysis Syndrome; Uric Acid | 2007 |
Dendritic cells and innate defense against tumor cells.
Topics: Apoptosis; Benzamides; Biomarkers, Tumor; Cancer Vaccines; CpG Islands; Cytokines; Dendritic Cells; | 2008 |
The detection of environmental mutagens and potential carcinogens.
Topics: Aging; Animals; Biological Assay; Biotransformation; Carcinogens, Environmental; DNA; DNA Repair; Fe | 1984 |
Renal manifestations of extrarenal neoplasms.
Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm | 1980 |
Fluid and electrolyte disturbances associated with cancer and its treatment.
Topics: Blood Volume; Body Water; Calcium; Humans; Hypercalcemia; Hyperkalemia; Hypocalcemia; Hypokalemia; I | 1982 |
Cancer and the kidney: complications of neoplasms.
Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypercalcemia; I | 1981 |
Emergencies in oncology. Current management.
Topics: Airway Obstruction; Brain Neoplasms; Cardiac Tamponade; Embolism; Emergencies; Humans; Hypercalcemia | 1978 |
Common emergencies in cancer medicine: metabolic syndromes.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adrenal Cortex Diseases; Emergencies; Humans; Hypercalcemia; | 1991 |
[Isolation of factors responsible for the immunosuppression found in tumor-bearing animals].
Topics: Adenosine; Animals; Glycoproteins; Humans; Immune Tolerance; Macrophage Activation; Macrophages; Mic | 1985 |
Cancer chemotherapy. 3.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Allopurinol; Alopecia; Antimetabolites; Antineoplast | 1972 |
Uric acid nephrolithiasis.
Topics: Adolescent; Aged; Allopurinol; Female; Humans; Hydrogen-Ion Concentration; Kidney Calculi; Male; Met | 1968 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; | 1969 |
6 trials available for uric acid and Neoplasms
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Plasma Urate, Cancer Incidence, and All-Cause Mortality: A Mendelian Randomization Study.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Cause of Death; Genotype; Glucose Transport Proteins, Facil | 2017 |
Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hy | 2016 |
Recombinant urate oxidase (rasburicase) in the prevention and treatment of malignancy-associated hyperuricemia in pediatric and adult patients: results of a compassionate-use trial.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Humans; In | 2001 |
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.
Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolenc | 2001 |
Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.
Topics: Age Factors; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Clinical Trials as Topic; Cytar | 1971 |
130 other studies available for uric acid and Neoplasms
Article | Year |
---|---|
Pseudo-tumor of the patella due to gout tophi.
Topics: Arthritis, Gouty; Gout; Humans; Neoplasms; Patella; Uric Acid | 2022 |
Diagnostic Value of Lactate Dehydrogenase and Uric Acid as Screening Tools for Malignancies in Children.
Topics: Biomarkers; Child; Humans; L-Lactate Dehydrogenase; Neoplasms; Retrospective Studies; ROC Curve; Uri | 2022 |
Incidence and Risk Factors for Acute Kidney Injury After Chimeric Antigen Receptor T-Cell Therapy.
Topics: Acute Kidney Injury; Antigens, CD19; Cell- and Tissue-Based Therapy; Contrast Media; Creatine Kinase | 2022 |
Renal NF-κB activation impairs uric acid homeostasis to promote tumor-associated mortality independent of wasting.
Topics: Animals; Carrier Proteins; Drosophila; Homeostasis; Neoplasms; NF-kappa B; Uric Acid | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Bioresource-derived colloidal nitrogen-doped graphene quantum dots as ultrasensitive and stable nanosensors for detection of cancer and neurotransmitter biomarkers.
Topics: Biomarkers; Dopamine; Graphite; Humans; Neoplasms; Neurotransmitter Agents; Nitrogen; Quantum Dots; | 2022 |
Cancer antigen 125 and C-reactive protein inflammatory mediators and uric acid in association with preeclampsia in North Kordofan State, Western Sudan.
Topics: C-Reactive Protein; CA-125 Antigen; Case-Control Studies; Female; Humans; Inflammation Mediators; Ne | 2023 |
U-Shaped Association of Serum Uric Acid With All-Cause and Cause-Specific Mortality in US Adults: A Cohort Study.
Topics: Adult; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Hyperuricemia; Male; | 2020 |
Predictive factors of tumour necrosis inhibitor treatment persistence for rheumatoid arthritis: An observational study in 8052 patients.
Topics: Aged; Arthritis, Rheumatoid; Female; Gout; Gout Suppressants; Humans; Male; Middle Aged; Necrosis; N | 2020 |
Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia.
Topics: Adult; Allopurinol; Female; Humans; Hyperuricemia; Kaplan-Meier Estimate; Male; Middle Aged; Neoplas | 2020 |
The coadministration of trehalose dibehenate and monosodium urate crystals promotes an antitumor phenotype in human-derived myeloid cells.
Topics: Animals; Humans; Macrophages; Mice; Monocytes; Neoplasms; Phenotype; Trehalose; Uric Acid | 2020 |
Cancer in chronic heart failure patients in the GISSI-HF trial.
Topics: Aged; Blood Pressure; Cardiovascular Diseases; Cause of Death; Cholesterol; Chronic Disease; Creatin | 2020 |
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity.
Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation | 2021 |
Identification of two novel subgroups in patients with diabetes mellitus and their association with clinical outcomes: A two-step cluster analysis.
Topics: Adult; Age of Onset; Aged; Body Mass Index; China; Cluster Analysis; Cohort Studies; Diabetes Compli | 2021 |
Is there relationship between serum uric acid levels and lower urinary tract symptoms, prostate volume, and PSA in men without cancer? A prospective population-based study.
Topics: Aged; Humans; Lower Urinary Tract Symptoms; Male; Middle Aged; Neoplasms; Prospective Studies; Prost | 2021 |
Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population.
Topics: Bilirubin; Humans; Male; Neoplasms; Prospective Studies; Republic of Korea; Serum Albumin; Uric Acid | 2021 |
Nutrition Status and Renal Function as Predictors in Acute Myocardial Infarction with and without Cancer: A Single Center Retrospective Study.
Topics: Aged; Female; Humans; Kidney; Logistic Models; Male; Middle Aged; Myocardial Infarction; Neoplasms; | 2021 |
Association of serum uric acid with increased risk of cancer among hypertensive Chinese.
Topics: Adult; Aged; Asian People; China; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Ag | 2017 |
Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study.
Topics: Female; Follow-Up Studies; Humans; Incidence; Male; Neoplasms; Population Surveillance; Proportional | 2017 |
Albumin, bilirubin, uric acid and cancer risk: results from a prospective population-based study.
Topics: Adult; Aged; Bilirubin; Cohort Studies; Female; Humans; Male; Middle Aged; Neoplasms; Proportional H | 2017 |
A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates.
Topics: Adenine Phosphoribosyltransferase; Databases, Factual; DNA Copy Number Variations; DNA Methylation; | 2018 |
[Study of arginase activity of mixed saliva in cancer].
Topics: Adult; Aged; Arginase; Female; Humans; Male; Middle Aged; Neoplasm Proteins; Neoplasms; Nitric Oxide | 2016 |
Crystal-proven gout patients have an increased mortality due to cardiovascular diseases, cancer, and infectious diseases especially when having tophi and/or high serum uric acid levels: a prospective cohort study.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Communicable Diseases; Female; Gout; Humans; Hyperuri | 2019 |
Utilization patterns and clinical outcomes of rasburicase administration according to tumor risk stratification.
Topics: Acute Kidney Injury; Aged; Female; Gout Suppressants; Humans; Hyperuricemia; Male; Middle Aged; Neop | 2020 |
Enterosorption as a method to decrease the systemic toxicity of cisplatin.
Topics: Animals; Antineoplastic Agents; Body Weight; Carbon; Cisplatin; Creatinine; Enterosorption; Kidney; | 2013 |
The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense.
Topics: Antioxidants; Biological Transport; Cell Line, Tumor; DNA Damage; Glucose Transport Proteins, Facili | 2015 |
Serum uric acid levels and cancer mortality risk among males in a large general population-based cohort study.
Topics: Adult; Cohort Studies; Colorectal Neoplasms; Humans; Lung Neoplasms; Male; Neoplasms; Netherlands; P | 2014 |
Extreme clinical chemistry.
Topics: Biomarkers; Chemistry, Clinical; Humans; Metabolic Diseases; Neoplasms; Serum Albumin; Tangier Disea | 2015 |
High Serum Uric Acid Levels Are Associated with All-Cause and Cardiovascular, but Not Cancer, Mortality in Elderly Adults.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Male; Neoplasms; Risk | 2015 |
Association between uric acid, cancer incidence and mortality in patients with type 2 diabetes: Shanghai diabetes registry study.
Topics: Aged; China; Diabetes Mellitus, Type 2; Female; Humans; Hyperuricemia; Incidence; Male; Middle Aged; | 2016 |
Monosodium Urate Crystals Induce Upregulation of NK1.1-Dependent Killing by Macrophages and Support Tumor-Resident NK1.1+ Monocyte/Macrophage Populations in Antitumor Therapy.
Topics: Animals; Antigens, Ly; Carrier Proteins; Cell Line, Tumor; Granzymes; Inflammasomes; Interleukin-1be | 2015 |
Uric acid enhances the antitumor immunity of dendritic cell-based vaccine.
Topics: Adjuvants, Immunologic; Adoptive Transfer; Animals; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cyt | 2015 |
High Uric Acid (UA) Negatively Affects Serum Tartrate-Resistant Acid Phosphatase 5b (TRACP 5b) Immunoassay.
Topics: Acid Phosphatase; Adolescent; Adult; Aged; Biomarkers, Tumor; Bone Neoplasms; Bone Resorption; Case- | 2016 |
Prevalence and possible causes of hypouricemia at a tertiary care hospital.
Topics: Adult; Aged; Allopurinol; Angiotensin Receptor Antagonists; Diabetes Mellitus; Female; Humans; Male; | 2016 |
[Analysis of the 2015 British guidelines on the prevention and management of tumor lysis syndrome].
Topics: Adult; Allopurinol; Child; Hematologic Neoplasms; Humans; Incidence; Neoplasms; Practice Guidelines | 2017 |
Use of penalized splines in extended Cox-type additive hazard regression to flexibly estimate the effect of time-varying serum uric acid on risk of cancer incidence: a prospective, population-based study in 78,850 men.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Humans; Incidence; Male; Middle Aged; Neopla | 2009 |
Single-dose rasburicase for tumour lysis syndrome in adults: weight-based approach.
Topics: Aged; Antineoplastic Agents; Creatinine; Drug Costs; Female; Gout Suppressants; Humans; Hyperuricemi | 2009 |
Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up.
Topics: Biomarkers; Blood Glucose; Cholesterol, HDL; England; Follow-Up Studies; Glucose Intolerance; Humans | 2010 |
Blood uric acid and proteose, body temperature, and glomerular clearance of rabbits implanted with the Brown-Pearce carcinoma and treated with the polysaccharide from Serratia marcescens.
Topics: Animals; Bacteria; Blood; Body Temperature; Carcinoma, Brown-Pearce; Humans; Kidney; Neoplasms; Neop | 1946 |
Fixed-dose rasburicase 6 mg for hyperuricemia and tumor lysis syndrome in high-risk cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Dose-Response Relationship, Drug; Drug Administration Sc | 2010 |
World congress on insulin resistance, diabetes, and cardiovascular disease: Part 1.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, T | 2011 |
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia.
Topics: Allopurinol; Animals; Body Composition; Body Weight; Cachexia; Caspase 3; Enzyme Inhibitors; Male; N | 2012 |
Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine.
Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Carbon Radioisotopes; Creatinine; Cys | 2012 |
Catabolism of xanthine and uracil in tumor-bearing rats.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Hydantoins; Liver Neoplasms; Neoplasms; N | 1962 |
THE BENIGN PURPURIC HYPERGLOBULINEMIA OF WALDENSTROM.
Topics: Blood; Blood Proteins; Collagen Diseases; Humans; Neoplasms; Purpura; Purpura, Hyperglobulinemic; Rh | 1964 |
THE BIOCHEMICAL BASIS FOR THE DIFFERENTIAL SENSITIVITY OF INTESTINAL MUCOSA AND BONE MARROW TO 6-THIOGUANINE.
Topics: Antineoplastic Agents; Bone Marrow; Intestinal Mucosa; Intestine, Small; Intestines; Metabolism; Neo | 1963 |
PROTEIN-BOUND DYE AND PURINE-CATABOLYZING ENZYMES IN PARENCHYMAL AND NONPARENCHYMAL CELLS OF RATS FED 4-DIMETHYLAMINOAZOBENZENE.
Topics: Azo Compounds; Carcinogens; Enzymes; Guanine; Histocytochemistry; Liver; Liver Neoplasms; N-Glycosyl | 1964 |
ANURIA DUE TO URIC ACID CRYSTALLURIA: AN UNUSUAL COMPLICATION OF THERAPY IN THE RETICULOSES.
Topics: Abdominal Neoplasms; Anuria; Blood; Genetic Diseases, X-Linked; Humans; Kidney Diseases; Leukemia, H | 1964 |
ACUTE RENAL FAILURE COMPLICATING LYMPHOSARCOMA.
Topics: Acute Kidney Injury; Blood; Humans; Kidney; Kidneys, Artificial; Lymphoma; Lymphoma, Non-Hodgkin; Ne | 1965 |
URIC ACID IN HUMAN PLASMA. II. INVESTIGATIONS ON THE POSSIBLE PRESENCE OF URIC ACID COVALENTLY LINKED TO PLASMA MACROMOLECULES.
Topics: Arthritis; Arthritis, Rheumatoid; Blood; Chromatography; Chromatography, Gel; Female; Gout; Humans; | 1965 |
[STUDY OF KREBS CYCLE ACIDS IN CANCER].
Topics: Acids; Arthritis; Arthritis, Rheumatoid; Breast Neoplasms; Chromatography; Citric Acid Cycle; Female | 1964 |
PREVENTION OF HYPERURICEMIA IN LEUKEMIA AND LYMPHOMA: USE OF ALOPURINOL, A XANTHINE OXIDASE INHIBITOR.
Topics: Adolescent; Antineoplastic Agents; Blood; Blood Urea Nitrogen; Drug Therapy; Geriatrics; Humans; Hyp | 1965 |
Serum uric acid and risk of death from cancer, cardiovascular disease or all causes in men.
Topics: Adult; Age Factors; Aged; Diabetes Mellitus; Follow-Up Studies; Humans; Korea; Male; Middle Aged; Mu | 2004 |
Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study.
Topics: Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; Finland; Follow-Up Studies; | 2004 |
Uric acid and allantoin excretion in normal and tumor-bearing mice.
Topics: Allantoin; Animals; Biological Transport; Body Fluids; Mice; Neoplasms; Uric Acid | 1949 |
Reduced-dose rasburicase in the treatment of adults with hyperuricemia associated with malignancy.
Topics: Aged; Antineoplastic Agents; Creatinine; Female; Humans; Hyperuricemia; Leukemia; Lymphoma; Male; Mi | 2006 |
Reduced-dose rasburicase (recombinant xanthine oxidase) in adult cancer patients with hyperuricemia.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Female; Hematopoietic Stem Cell Transplantation; Humans; | 2006 |
Uric acid as a prognostic factor for survival time: a prospective cohort study of terminally ill cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Male; Middle Aged; Neoplasms; Predic | 2006 |
Effects of basal level of antioxidants on oxidative DNA damage in humans.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Antioxidants; Biomarkers; Chromatograph | 2007 |
Serum uric acid and risk of cancer mortality in a large prospective male cohort.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Follow-Up Studies; Humans; Longitudinal | 2007 |
The role of serum uric acid as an antioxidant protecting against cancer: prospective study in more than 28 000 older Austrian women.
Topics: Age Factors; Aged; Aged, 80 and over; Antioxidants; Austria; Biomarkers, Tumor; Cohort Studies; Fema | 2007 |
Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation.
Topics: Adenoviridae; Cell Line, Tumor; Dendritic Cells; Enzyme Activation; Humans; Neoplasms; Oncolytic Vir | 2008 |
The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity.
Topics: Animals; Antibodies; Cell Differentiation; Cell Line, Tumor; Crystallization; Interleukin-5; Leukocy | 2008 |
Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im
Topics: Acupuncture; Acupuncture Points; Blood Cell Count; Blood Glucose; C-Reactive Protein; Cardiovascular | 2007 |
Allopurinol in the treatment of neoplastic disease complicated by hyperuricemia.
Topics: Adult; Aged; Allopurinol; Enzyme Therapy; Enzymes; Female; Humans; Kidney; Male; Middle Aged; Neopla | 1967 |
Hypouricaemic effect of polyethyleneglycol modified urate oxidase.
Topics: Aged; Allantoin; Allopurinol; Candida; Humans; Male; Middle Aged; Neoplasms; Polyethylene Glycols; U | 1981 |
Raised serum urate concentration as risk factor for premature mortality in middle aged men: relation to death from cancer.
Topics: Body Weight; Cholesterol; Creatinine; Humans; Male; Middle Aged; Neoplasms; Risk; Uric Acid | 1983 |
Raised serum urate concentration as risk factor for premature mortality in middle aged men.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Neoplasms; Risk; Uric Acid | 1984 |
Hypoxanthine concentrations in normal subjects and patients with solid tumors and leukemia.
Topics: Acute Disease; Allopurinol; Bone Marrow; Cell Division; Cell Line; Chromatography, High Pressure Liq | 1984 |
Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.
Topics: Adult; Aging; Animals; Antioxidants; Ascorbic Acid; Biological Evolution; Brain; Digestive System; E | 1981 |
The clinical pharmacology of the adenosine deaminase inhibitor 2'-deoxycoformycin.
Topics: Adenosine Deaminase Inhibitors; Adult; Aged; Animals; Coformycin; Dogs; Female; Humans; Kinetics; Le | 1980 |
Renal and metabolic toxicities of cancer chemotherapy.
Topics: Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Electrolytes; Glomerular Filtration | 1982 |
[Secondary diseases complicating cancer].
Topics: Cardiovascular Diseases; Coronary Disease; Diabetes Complications; Female; Heart Failure; Humans; Li | 1981 |
Urolithiasis in hyperuricemia and gout.
Topics: Adult; Allopurinol; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Myelo | 1981 |
Tumoural hypouricemia.
Topics: Autoanalysis; Creatinine; Humans; Neoplasms; Pyrazinamide; Uric Acid | 1980 |
Hypouricaemia in a hospital population.
Topics: Diabetes Mellitus; Female; Humans; Intensive Care Units; Male; Neoplasms; Sex Factors; Uric Acid | 1993 |
Renal, metabolic, and hemodynamic side-effects of interleukin-2 and/or interferon alpha: evidence of a risk/benefit advantage of subcutaneous therapy.
Topics: Adult; Aged; Blood Proteins; Blood Urea Nitrogen; Creatinine; Electrolytes; Female; Hemodynamics; Hu | 1993 |
Serum carotenoids and uric acid levels in relation to cancer.
Topics: Adult; Aged; Carotenoids; Female; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Uric Ac | 1996 |
Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid.
Topics: Antioxidants; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Female; Glutathione; Glutathione Disulfid | 1997 |
Serum selenium levels as indicators of body status in cancer patients and their relationship with other nutritional and biochemical markers.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers | 1998 |
Cancer mortality trends in two cohorts of elderly people having different life-styles.
Topics: Age Distribution; Aged; Aging; Alanine Transaminase; Alkaline Phosphatase; Body Mass Index; Cohort S | 1999 |
Predictors of cancer mortality in elderly subjects.
Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Body Mass Index; Cholesterol; Fe | 1999 |
Allopurinol: intravenous use for prevention and treatment of hyperuricemia.
Topics: Adult; Allopurinol; Child; Enzyme Inhibitors; Humans; Infusions, Intravenous; Kidney Diseases; Neopl | 2000 |
Serum antioxidant and cholesterol levels in patients with different types of cancer.
Topics: Adult; alpha-Tocopherol; Antioxidants; Arabs; Case-Control Studies; Child; Cholesterol; Chromatograp | 2001 |
[Basic therapy in children with leukemia and a malignant tumors. II].
Topics: Allopurinol; Anaphylaxis; Anemia; Antibiotics, Antineoplastic; Bicarbonates; Blood Transfusion; Chil | 1978 |
Acute renal failure associated with neoplastic disease and its treatment.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Female; Humans; Hyperc | 1978 |
Ampicillin rash and hyperuricemia.
Topics: Allopurinol; Ampicillin; Drug Eruptions; Drug Interactions; Humans; Immunosuppression Therapy; Neopl | 1979 |
[Frequency and distribution of types of hyperlipoproteinemia with life-shortening risk factors among ambulant patients (author's transl)].
Topics: Cholesterol; Diabetes Complications; Female; Germany, West; Gout; Humans; Hyperlipidemias; Hypertens | 1975 |
[Hypouricaemia (author's transl)].
Topics: Allopurinol; Fanconi Syndrome; Humans; Liver Diseases; Neoplasms; Purine-Pyrimidine Metabolism, Inbo | 1979 |
Simultaneous analysis of substrates, products, and inhibitors of xanthine oxidase by high-pressure liquid chromatography and gas chromatography.
Topics: Allopurinol; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Hypoxanthines; Neopl | 1979 |
[Treatment-induced complications and frequent errors in cytostatic therapy].
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Hum | 1978 |
Variables predictive of bone marrow metastasis.
Topics: Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Bone and Bones; Bone Marrow Diseases; Bone M | 1978 |
Pharmacological and biochemical effects of pyrazofurin in humans.
Topics: Amides; Antibiotics, Antineoplastic; Drug Administration Schedule; Female; Half-Life; Humans; Infusi | 1977 |
Hyperuricaemia as an index of the response to chemotherapy in solid tumors.
Topics: Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Neoplasms; Prognosis; | 1977 |
Diuretics in malignant effusions and edemas of generalized cancer.
Topics: Ascites; Body Weight; Bumetanide; Diuretics; Drinking; Edema; Furosemide; Humans; Neoplasms; Pleuris | 1976 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; C | 1975 |
Selenium, retinol, retinol-binding protein, and uric acid: from epidemiology to clinical prevention trials.
Topics: Biomarkers; Biomarkers, Tumor; Humans; Neoplasms; Retinol-Binding Proteins; Selenium; Uric Acid; Vit | 1992 |
Urate metabolism during bone marrow transplantation.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined M | 1992 |
Selenium, retinol, retinol-binding protein, and uric acid. Associations with cancer mortality in a population-based prospective case-control study.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Male; Neoplasms; | 1991 |
Selenium, retinol, retinol-binding protein, and uric acid. From epidemiology to clinical prevention trials.
Topics: Humans; Neoplasms; Retinol-Binding Proteins; Selenium; Uric Acid; Vitamin A | 1991 |
Clinical significance of hypouricemia in hospitalized patients.
Topics: Adolescent; Adult; Aged; Allopurinol; Anti-Bacterial Agents; Antineoplastic Agents; Child; Female; G | 1991 |
Phase I clinical and pharmacological study of merbarone.
Topics: Adult; Aged; Antineoplastic Agents; Creatinine; Drug Administration Schedule; Drug Evaluation; Femal | 1990 |
Explanations for the hypouricemia noted in cancer patients.
Topics: Anorexia; Humans; Neoplasms; Uric Acid | 1990 |
[Cancer and hyperuricemia--an analysis of 316 cancer patients].
Topics: Adult; Aged; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neoplasms; Uric Acid; Urinary Blad | 1989 |
Serum uric acid and 11.5-year mortality of middle-aged women: findings of the Chicago Heart Association Detection Project in Industry.
Topics: Adult; Cardiovascular Diseases; Coronary Disease; Female; Humans; Male; Middle Aged; Mortality; Neop | 1989 |
Serum urate level and cancer.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Neoplasms; Uric Acid | 1989 |
[How to prevent the tumor lysis syndrome].
Topics: Anuria; Humans; Neoplasms; Phosphates; Syndrome; Uric Acid | 1985 |
Low plasma selenium as a risk factor for cancer death in middle-aged men.
Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; beta 2-Microglobulin; Cholesterol; Humans; | 1987 |
Serum uric acid unrelated to cancer incidence in humans.
Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Regression Analysis; Risk Factors; Uric Acid | 1988 |
Metabolic emergencies in pediatric oncology: the acute tumor lysis syndrome.
Topics: Child; Emergencies; Humans; Hyperkalemia; Hypocalcemia; Metabolic Diseases; Neoplasms; Phosphates; U | 1987 |
[Utility of the uric acid clearance method as a marker of antitumor effect of chemotherapy in cases of malignancies].
Topics: Adult; Aged; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Uric Acid | 1987 |
beta-Aminoisobutyric acid as a marker of thymine catabolism in malignancy.
Topics: Adolescent; Aminobutyrates; Child; Child, Preschool; Humans; Infant; Leukocyte Count; Neoplasms; Pur | 1987 |
[Amino acid and protein metabolism in critically ill patients].
Topics: Adult; Aged; Amino Acids; Animals; Blood Proteins; Cholecystectomy; Critical Care; Dogs; Female; Hum | 1985 |
Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
Topics: Adult; Aged; Antineoplastic Agents; Aspartate Aminotransferases; Bone Marrow; Creatine Kinase; Drug | 1985 |
Oncologic emergencies I. Metabolic and space-occupying consequences of cancer and cancer treatment.
Topics: Calcium; Child; Constriction, Pathologic; Emergencies; Humans; Neoplasms; Phosphates; Potassium; Pur | 1985 |
Letter: Allopurinol and bone-marrow depression.
Topics: Acute Kidney Injury; Allopurinol; Bone Marrow; Cyclophosphamide; Drug Synergism; Humans; Neoplasms; | 1974 |
[General medical measures in neoplastic diseases and their complications].
Topics: Anemia; Central Nervous System Diseases; Humans; Hypercalcemia; Hyperinsulinism; Hyperparathyroidism | 1967 |
Letter: Hyperphosphatemia and hypocalcemia in neoplastic disorders.
Topics: Aged; Animals; Antineoplastic Agents; Child, Preschool; Cholecalciferol; Humans; Hypocalcemia; Leuke | 1974 |
Relationship between urinary beta-aminoisobutyric acid and transfer RNA turnover in cancer patients.
Topics: Aged; Aminoisobutyric Acids; Carcinoma, Transitional Cell; Colonic Neoplasms; DNA, Neoplasm; Female; | 1974 |
Preliminary clinical experience with cis-diamminedichloroplatinum (II) (NSC 119875, CACP).
Topics: Amines; Anemia; Antineoplastic Agents; Audiometry; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cel | 1972 |
The clinical significance of hypouricemia.
Topics: Allopurinol; Aspirin; Contrast Media; Depression, Chemical; Diet; Female; Guaifenesin; Humans; Liver | 1973 |
Methrotrexate U.S.P. (amethopterin) and methotrexate sodium.
Topics: Abortion, Induced; Anemia; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Choriocarcinoma | 1973 |
Causes of hypouricemia.
Topics: Adult; Alcoholism; Female; Humans; Liver Diseases; Male; Middle Aged; Neoplasms; Salicylates; Uric A | 1973 |
[Emergencies in oncology].
Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Breast Neoplasms; Carcinoma; Emergencies; Estradiol; | 1973 |
Proceedings: Cyclophosphamide and the kidney.
Topics: Adolescent; Adult; Amino Acids; Body Weight; Calcium; Cyclophosphamide; Cystitis; Diuresis; Female; | 1974 |
Pharmacogenetics.
Topics: Abnormalities, Drug-Induced; Allopurinol; Barbiturates; Chromosome Aberrations; Drug-Related Side Ef | 1974 |
The clinical significance of hypouricemia.
Topics: Allopurinol; Amino Acids; Aspirin; Autoanalysis; Creatinine; Glycosuria; Humans; Kidney Diseases; Ne | 1974 |
Synthesis and oncogenicity of 3-hydroxyuric acid.
Topics: Animals; Benzyl Compounds; Carbon Isotopes; Carcinogens; Chemical Phenomena; Chemistry; Chromatograp | 1971 |
[Chemotherapy of cancer and alteration of body fluid constituents--evaluation of the treatment of cancer].
Topics: Adolescent; Animals; Antineoplastic Agents; Blood Proteins; Body Fluids; Female; Humans; Isoenzymes; | 1969 |
Hyperuricaemia in northern Finland. An epidemiological study of serum uric acid in rural, urban and hospital populations.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Body Weight; Cerebrovascular Disorders; Cholesterol; C | 1969 |
Hyperuricemia in neoplastic disease in children: prevention with allopurinol, a xanthine oxidase inhibitor.
Topics: Adolescent; Allopurinol; Blood Urea Nitrogen; Child; Child, Preschool; Female; Humans; Leukocyte Cou | 1968 |