Page last updated: 2024-10-20

uric acid and Nausea

uric acid has been researched along with Nausea in 30 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis."9.08Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997)
"Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks."7.67Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985)
"A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis."5.08Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997)
"The presence of nausea and vomiting, epigastric pain, or both in association with admission laboratory values that are in excess of the cutoffs for lactate dehydrogenase, aspartate aminotransferase, and uric acid concentrations or for all 6 tests is predictive of high risk of morbidity for the patient with severe preeclampsia."3.70Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999)
"Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks."3.67Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985)
"Long-term flexible dosing with colestilan reduces serum phosphorus and demonstrates an acceptable safety and tolerability profile."2.82Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia. ( Dimkovic, N; Locatelli, F; Spasovski, G; Wanner, C, 2016)
"Class 3 HELLP syndrome is considered a clinically significant transitional group."1.30The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999)
" How the adverse effects of and charges for this procedure compare with those of the standard marrow harvest is not known."1.29Clinical toxicity and laboratory effects of granulocyte-colony-stimulating factor (filgrastim) mobilization and blood stem cell apheresis from normal donors, and analysis of charges for the procedures. ( Anderlini, P; Champlin, R; Chan, KW; Körbling, M; Lichtiger, B; Miller, P; Norfleet, F; Przepiorka, D; Seong, D; Sundberg, J, 1996)
"Tiazofurin is a novel C-nucleoside with significant antitumor activity in murine tumor models."1.27Phase I trial of tiazofurin administered by i.v. bolus daily for 5 days, with pharmacokinetic evaluation. ( Culham, CA; Hartshorn, JN; Haugh, LD; Krakoff, IR; McCormack, JJ; Newman, RA; Roberts, JD; Stewart, JA; Young, JA, 1987)
"Azosemide is a new loop diuretic which has been shown to affect solute transport proximal to the diluting segment."1.26Effects in normal subjects of long-term administration of azosemide. ( Anderson, S; Brater, C; Muckleroy, C, 1979)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199024 (80.00)18.7374
1990's4 (13.33)18.2507
2000's1 (3.33)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Locatelli, F1
Spasovski, G1
Dimkovic, N1
Wanner, C1
Shils, ME1
Emmerson, BT1
Neyer, U1
Wöss, E1
Haller, R1
Kröss, R1
Smyth, JF1
Paine, RM1
Jackman, AL1
Harrap, KR1
Chassin, MM1
Adamson, RH1
Johns, DG1
Anderlini, P1
Przepiorka, D1
Seong, D1
Miller, P1
Sundberg, J1
Lichtiger, B1
Norfleet, F1
Chan, KW1
Champlin, R1
Körbling, M1
Banks, PA1
Hughes, M1
Ferrante, M1
Noordhoek, EC1
Ramagopal, V1
Slivka, A1
Martin, JN2
Rinehart, BK2
May, WL2
Magann, EF2
Terrone, DA2
Blake, PG2
Carducci, MA1
Gilbert, J1
Bowling, MK1
Noe, D1
Eisenberger, MA1
Sinibaldi, V1
Zabelina, Y1
Chen, TL1
Grochow, LB1
Donehower, RC1
Brater, C1
Anderson, S1
Muckleroy, C1
Merrin, C1
Matzkies, F2
Hirschel, B1
Bosl, R1
Shideman, JR1
Meyer, RM1
Buselmeier, TJ1
von Hartitzsch, B1
Kjellstrand, CM1
Simonson, GM1
Roberts, JD1
Stewart, JA1
McCormack, JJ1
Krakoff, IR1
Culham, CA1
Hartshorn, JN1
Newman, RA1
Haugh, LD1
Young, JA1
Higgins, GR1
Jamin, DC1
Shore, NA1
Momparler, R1
Hartman, G1
Siegel, SE1
Dubiel, W1
Happle, R1
Berg, G1
Bickel, H1
Zeilhofer, R1
Perheentupa, J1
Raivio, KO1
Nikkilä, EA1
Hutchison, JC1
Oettgen, HF1
Stephenson, PA1
Schwartz, MK1
Leeper, RD1
Tallai, L1
Tan, CC1
Clarkson, BD1
Golbey, RB1
Krakoff, IH1
Karnofsky, DA1
Murphy, ML1
Burchenal, JH1
Gifford, RW1
Harvengt, C1
Lavenne, F1
Kennedy, CC1
Spiekerman, RE1
Elveback, L1
Hartmann, G1
Schmid, R1
Storti, E1
Quaglino, D1
Barbeau, A1
Mars, H1
Gillo-Joffroy, L1
Lawlor, T1
Wells, DG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III, Multi-center, Open Label, Flexible Dose, Long Term Safety Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia[NCT00772382]Phase 3116 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Change in Serum Phosphorus From Baseline to Week 52

(NCT00772382)
Timeframe: 52 weeks

Interventionmg/dL (Mean)
MCI-196-1.18

Number of Adverse Events (AE)

(NCT00772382)
Timeframe: 52 weeks

Interventionparticipants (Number)
At least 1 treatment-emergent AEAt least 1 drug-related treatment-emergent AEAt least 1 treatment-emergent serious AE
MCI-1961095063

Reviews

1 review available for uric acid and Nausea

ArticleYear
Hereditary fructose intolerance.
    Acta medica Scandinavica. Supplementum, 1972, Volume: 542

    Topics: 17-Ketosteroids; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Cholesterol; Diet The

1972

Trials

8 trials available for uric acid and Nausea

ArticleYear
Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia.
    Blood purification, 2016, Volume: 41, Issue:4

    Topics: Adult; Aged; Bile Acids and Salts; Cholesterol, LDL; Diarrhea; Female; Glycated Hemoglobin; Hemodial

2016
Does allopurinol reduce pain of chronic pancreatitis?
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1997, Volume: 22, Issue:3

    Topics: Abdominal Pain; Activities of Daily Living; Adult; Allopurinol; Ankle; Blood Cell Count; Chronic Dis

1997
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10

    Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolenc

2001
[Experimental treatment with fumaric acid monoethylester in psoriasis vulgaris].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Jul-01, Volume: 47, Issue:13

    Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Eruptio

1972
The hypotensive action of ethacrynic acid.
    Vascular diseases, 1968, Volume: 5, Issue:2

    Topics: Abdomen; Adult; Aged; Antihypertensive Agents; Black People; Blood Glucose; Blood Pressure Determina

1968
Ethacrynic acid alone and in combination with methyldopa in the management of mild hypertension. A report of 23 patients.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:3

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diarrhea; Drug Synergism; Ethacrynic Acid; Fe

1970
[Influence of aluminum nicotinate on serum lipids].
    Acta cardiologica, 1969, Volume: 24, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aluminum; Arteriosclerosis; Blood Glucose; Cardiovascular Diseases; Cho

1969
Antihypertensive properties of cryptenamine used with reserpine and methyclothiazide.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:8

    Topics: Adult; Aged; Anorexia Nervosa; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight;

1971

Other Studies

21 other studies available for uric acid and Nausea

ArticleYear
EXPERIMENTAL HUMAN MAGNESIUM DEPLETION. I. CLINICAL OBSERVATIONS AND BLOOD CHEMISTRY ALTERATIONS.
    The American journal of clinical nutrition, 1964, Volume: 15

    Topics: Biomedical Research; Blood Chemical Analysis; Calcium; Calcium, Dietary; Cholesterol; Electromyograp

1964
Regimen of indomethacin therapy in acute gouty arthritis.
    British medical journal, 1967, Apr-29, Volume: 2, Issue:5547

    Topics: Adult; Creatine; Female; Gout; Headache; Humans; Indomethacin; Male; Middle Aged; Nausea; Urea; Uric

1967
[Headache and EEG changes caused by acetate and bicarbonate dialysis].
    Acta medica Austriaca, 1983, Volume: 10, Issue:1

    Topics: Acetates; Acid-Base Equilibrium; Adult; Bicarbonates; Electroencephalography; Headache; Humans; Naus

1983
The clinical pharmacology of the adenosine deaminase inhibitor 2'-deoxycoformycin.
    Cancer chemotherapy and pharmacology, 1980, Volume: 5, Issue:2

    Topics: Adenosine Deaminase Inhibitors; Adult; Aged; Animals; Coformycin; Dogs; Female; Humans; Kinetics; Le

1980
Clinical toxicity and laboratory effects of granulocyte-colony-stimulating factor (filgrastim) mobilization and blood stem cell apheresis from normal donors, and analysis of charges for the procedures.
    Transfusion, 1996, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Alkaline Phosphatase; Analgesics; Blood Transfusion, Autologous; Bone Marrow Tran

1996
The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:6 Pt 1

    Topics: Aspartate Aminotransferases; Birth Weight; Cesarean Section; Eclampsia; Female; Fetal Death; Headach

1999
Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:6 Pt 1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Creatinine; Female; HELLP Syndrome; Humans; L-Lac

1999
Effects in normal subjects of long-term administration of azosemide.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:4

    Topics: Diet, Sodium-Restricted; Diuretics; Drug Evaluation; Headache; Humans; Nausea; Potassium; Renin; Sod

1979
Treatment of advanced bladder cancer with cis-diamminedichloroplatinum (II NSC 119875): a pilot study.
    The Journal of urology, 1978, Volume: 119, Issue:4

    Topics: Carcinoma, Transitional Cell; Cisplatin; Female; Humans; Leukopenia; Male; Nausea; Neoplasm Metastas

1978
[Effects and side effects of benzbromaron in the initial treatment of hyperuricemia and gout. Results of a field study on 3899 patients].
    Fortschritte der Medizin, 1978, Aug-24, Volume: 96, Issue:32

    Topics: Benzbromarone; Benzofurans; Diarrhea; Female; Gout; Humans; Kidney Calculi; Male; Nausea; Uric Acid

1978
[Dr. Atkins' dietetic revolution: a critique].
    Schweizerische medizinische Wochenschrift, 1977, Jul-23, Volume: 107, Issue:29

    Topics: Acidosis; Adult; Cholesterol; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Energy Intake; Hu

1977
Effects and complications of high efficiency dialysis.
    Nephron, 1975, Volume: 15, Issue:2

    Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote

1975
Caring for patients with acute myelocytic leukemia.
    The American journal of nursing, 1988, Volume: 88, Issue:3

    Topics: Bone Marrow; Daunorubicin; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1988
Phase I trial of tiazofurin administered by i.v. bolus daily for 5 days, with pharmacokinetic evaluation.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Adult; Aged; Allopurinol; Antimetabolites, Antineoplastic; Creatine Kinase; Drug Administration Sche

1987
Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Acute Disease; Acute Kidney Injury; Child; Deoxyguanosine; Drug Evaluation; Humans; Leukemia; Leukem

1985
[Acid-base equilibrium in long-term infusions of xylitol, fructose, glucose and carbohydrate mixtures].
    Zeitschrift fur Ernahrungswissenschaft. Journal of nutritional sciences. Supplementa, 1973, Volume: 15

    Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Blood; Carbon Dioxide; Carbonates; Chlorides; Drug Inter

1973
Toxicity of E. coli L-asparaginase in man.
    Cancer, 1970, Volume: 25, Issue:2

    Topics: Adult; Agranulocytosis; Antigen-Antibody Reactions; Asparaginase; Blood Platelet Disorders; Bone Mar

1970
[Prolonged fasting as a method of treating obesity].
    Deutsche medizinische Wochenschrift (1946), 1967, Sep-15, Volume: 92, Issue:37

    Topics: Acid-Base Equilibrium; Aged; Coronary Disease; Diabetes Mellitus; Diabetic Ketoacidosis; Fasting; Fa

1967
Dysmetabolic and neurological complications in leukemia patients treated with L-asparaginase.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Asparaginase; Central Nervous System Diseases; Child; Clinical Enzyme Tests; Drug Hypersensitivity;

1970
Adverse clinical side effects of levodopa therapy.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede

1971
Metabolic hazards of fasting.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:8

    Topics: Adult; Anemia; Autoanalysis; Blood Cell Count; Blood Proteins; Blood Urea Nitrogen; Body Weight; Chl

1969