Page last updated: 2024-10-20

uric acid and Myocardial Ischemia

uric acid has been researched along with Myocardial Ischemia in 51 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"We studied effects of beta-adrenoblocker carvedilol vs placebo in 60 patients with chronic cardiac failure (CCF) of functional classes III-IV in a 6-month open randomized trial."9.10[Endothelial protection in patients with apparent cardiac failure in long-term therapy by carvedilol]. ( Shliakhto, EV; Sitnikova, MIu, 2003)
"We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF)."7.79Serum uric acid levels are associated with atrial fibrillation in patients with ischemic heart failure. ( Erbay, AR; Tekin, G; Tekin, YK; Turhan, H; Yetkin, E, 2013)
"Comparison of the serum uric acid levels of healthy people (n=71) and patients with cardiovascular diseases (CVD) (n=62)."7.70Serum uric acid levels in cardiovascular diseases. ( Burgaz, S; Simsek, B; Torun, M; Yardim, S, 1998)
" The serum concentrations of hypoxanthine, xanthine, uric acid and allantoin were determined in peripheral blood samples from patients with angina pectoris, cerebral insult and myocardial infarction with thrombolytic therapy and were compared with the concentrations obtained for healthy males and females."7.69A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases. ( Delvoux, B; Greiling, H; Kock, R; Sigmund, M, 1994)
"Allopurinol is a urate-lowering therapy used to treat patients with gout."5.51Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial. ( Avery, AJ; Barr, RJ; Begg, AG; Duce, SL; Dumbleton, JS; Ford, I; Greenlaw, N; Hawkey, CJ; MacDonald, TM; Mackenzie, IS; Pigazzani, F; Ritchie, LD; Rogers, A; Rooke, ED; Struthers, AD; Taggar, JS; Townend, JN; Walker, A; Wei, L, 2022)
"We studied effects of beta-adrenoblocker carvedilol vs placebo in 60 patients with chronic cardiac failure (CCF) of functional classes III-IV in a 6-month open randomized trial."5.10[Endothelial protection in patients with apparent cardiac failure in long-term therapy by carvedilol]. ( Shliakhto, EV; Sitnikova, MIu, 2003)
" The aim of this work was to study the relationship between the Cortisol blood level and the intensity of free radical reactions in patients with acute myocardial ischemia and acute myocardial infarction with respect to metabolic (glucose, uric acid) and enzymatic agents of ischemia and necrosis."5.09[Cortisol levels in blood of persons with acute myocardial ischemia and myocardial infarction]. ( Domański, L, 1999)
" Hyperuricemia was defined as serum uric acid levels exceeding 7."4.31Major adverse cardiovascular events and hyperuricemia during tuberculosis treatment. ( Jeong, SH; Kho, BG; Kim, TO; Kim, YI; Kwon, YS; Lee, JK; Lim, SC; Na, YO; Shin, HJ; Yoon, JY, 2023)
"We evaluated the association between serum uric acid (SUA) and atrial fibrillation (AF) in patients with chronic heart failure (HF)."3.79Serum uric acid levels are associated with atrial fibrillation in patients with ischemic heart failure. ( Erbay, AR; Tekin, G; Tekin, YK; Turhan, H; Yetkin, E, 2013)
" The objective of the present study was determination of incidence of selected risk factors of IHD, such as overweight and obesity, tobacco smoking, arterial hypertension, type 2 diabetes mellitus, dyslipidaemia, and elevated serum concentration of uric acid."3.72Selected risk factors of ischemic heart disease in Polish seafarers. Preliminary report. ( Filikowski, J; Renke, W; Rzepiak, M; Smolińska, D; Winnicka, A, 2003)
"Acetaminophen was administered acutely at the onset of reperfusion after 20 min of low-flow, global myocardial ischemia in isolated, perfused guinea pig hearts (Langendorff) to evaluate its influence in the postischemia, reperfused myocardium."3.71Acetaminophen in the post-ischemia reperfused myocardium. ( Golfetti, R; Merrill, G; Rork, T; Spiler, N; VanDyke, K, 2002)
"Comparison of the serum uric acid levels of healthy people (n=71) and patients with cardiovascular diseases (CVD) (n=62)."3.70Serum uric acid levels in cardiovascular diseases. ( Burgaz, S; Simsek, B; Torun, M; Yardim, S, 1998)
" The serum concentrations of hypoxanthine, xanthine, uric acid and allantoin were determined in peripheral blood samples from patients with angina pectoris, cerebral insult and myocardial infarction with thrombolytic therapy and were compared with the concentrations obtained for healthy males and females."3.69A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases. ( Delvoux, B; Greiling, H; Kock, R; Sigmund, M, 1994)
"Guizhi-Fuling (GZFL) is effective in treating Myocardial ischemia."1.72Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia. ( Duan, B; Han, L; Huang, F; Li, J; Wang, Q; Ye, Y; Yu, X; Zeng, X; Zhou, Z, 2022)
"Uric acid is a purine degradation product but also an important antioxidant and reactive oxygen species (ROS) scavenger."1.56Human concentrations of uric acid scavenges adaptive and maladaptive reactive oxygen species in isolated rat hearts subjected to ischemic stress. ( Boardman, NT; Chu, X; Falck, AT; Jenssen, TG; Lund, T; Martin-Armas, M; Norvik, JV; Ytrehus, K, 2020)
"Hyperlipidemia provokes inversion of correlation between the levels of uric acid, apo-E and apo-C3."1.34[Uric acid, apo-E and apo-C3 correlation in normo- and hyperlipidemia]. ( Boĭko, ER; Boĭko, SG; Kaneva, AM; Ovechkin, AO; Potolitsyna, NN, 2007)
" However, the concomitant production of superoxide and other reactive oxygen species (ROS) during I/R may diminish the bioavailability of NO and hence compromise the beneficial effects."1.33Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol. ( Colantuono, G; Khan, M; Kumbala, D; Kuppusamy, P; Kutala, VK; Mandal, R; Potaraju, V, 2006)
"Hypertension was the most common followed infrequency by dyslipidemia, diabetes mellitus, ischemic heart disease, and chronic obstructive pulmonary disease consecutively."1.32Clinical manifestations of patients with hyperuricemia. ( Akkasilpa, S; Avihingsanon, Y; Hanvivadhanakul, P; Wonchinsri, J, 2004)
"Deaths due to ischemic heart disease in both men and women increased when serum uric acid levels were in the highest quartile compared with the lowest quartile (men, >416 vs <321 micromol/L; risk ratio, 1."1.31Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. ( Alderman, MH; Fang, J, 2000)
"Hypoxanthine excretion was significantly elevated in patients compared with healthy controls (84."1.30Urinary hypoxanthine and xanthine levels in acute coronary syndromes. ( Bayindir, O; Boydak, B; Gülter, C; Habif, S; Mutaf, I; Ozmen, D; Senol, B; Turgan, N, 1999)
"There were no subjects with ischemic heart disease without the major and secondary risk factors."1.29Computer classification of screening study of risk factor for ischemic heart disease in 20-60 year old subjects. ( Valkov, Y, 1996)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (41.18)18.2507
2000's14 (27.45)29.6817
2010's11 (21.57)24.3611
2020's5 (9.80)2.80

Authors

AuthorsStudies
Duan, B1
Ye, Y1
Zhou, Z1
Han, L1
Huang, F1
Li, J1
Wang, Q1
Zeng, X1
Yu, X1
Mackenzie, IS1
Hawkey, CJ1
Ford, I1
Greenlaw, N1
Pigazzani, F1
Rogers, A1
Struthers, AD1
Begg, AG1
Wei, L1
Avery, AJ1
Taggar, JS1
Walker, A1
Duce, SL1
Barr, RJ1
Dumbleton, JS1
Rooke, ED1
Townend, JN1
Ritchie, LD1
MacDonald, TM1
Shin, HJ1
Yoon, JY1
Na, YO1
Lee, JK1
Kho, BG1
Kim, TO1
Kim, YI1
Lim, SC1
Jeong, SH1
Kwon, YS1
Boardman, NT1
Falck, AT1
Lund, T1
Chu, X1
Martin-Armas, M1
Norvik, JV1
Jenssen, TG1
Ytrehus, K1
Sandoval-Plata, G1
Nakafero, G1
Chakravorty, M1
Morgan, K1
Abhishek, A1
Tanaka, Y1
Nagoshi, T1
Kawai, M1
Uno, G1
Ito, S1
Yoshii, A1
Kimura, H1
Inoue, Y1
Ogawa, K1
Tanaka, TD1
Minai, K1
Ogawa, T1
Yoshimura, M1
Koza, Y1
Simsek, Z1
Tas, MH1
Palmer, TM1
Nordestgaard, BG1
Benn, M1
Tybjærg-Hansen, A1
Davey Smith, G1
Lawlor, DA1
Timpson, NJ1
Tekin, G2
Tekin, YK2
Kosacka, M1
Brzecka, A1
Piesiak, P1
Korzeniewska, A1
Jankowska, R1
Aribas, A1
Akilli, H1
Kayrak, M1
Alibasic, H1
Yildirim, O1
Sertdemir, AL1
Karanfil, M1
Ozdemir, K1
El-Bassossy, HM1
Watson, ML1
Iwasa, T1
Amiya, E1
Ando, J1
Watanabe, M1
Murasawa, T1
Komuro, I1
Jindrich, S1
Ondrej, L1
Viktor, M1
Zbynek, P1
Tomas, P1
Ladislav, D1
Jiri, V1
Lenka, S1
Miroslav, S1
Bahorun, T1
Luximon-Ramma, A1
Gunness, TK1
Sookar, D1
Bhoyroo, S1
Jugessur, R1
Reebye, D1
Googoolye, K1
Crozier, A1
Aruoma, OI1
Kozdağ, G1
Ertaş, G1
Aygün, F1
Emre, E1
Kirbaş, A1
Ural, D1
Soran, O1
Erbay, AR1
Turhan, H1
Yetkin, E1
Golfetti, R1
VanDyke, K1
Rork, T1
Spiler, N1
Merrill, G1
Sitnikova, MIu1
Shliakhto, EV1
Filikowski, J1
Rzepiak, M1
Renke, W1
Winnicka, A1
Smolińska, D1
Jee, SH1
Lee, SY1
Kim, MT1
Akkasilpa, S1
Avihingsanon, Y1
Hanvivadhanakul, P1
Wonchinsri, J1
Calberg, MJ1
Kjøller, E1
Baldus, S1
Müllerleile, K1
Chumley, P1
Steven, D1
Rudolph, V1
Lund, GK1
Staude, HJ1
Stork, A1
Köster, R1
Kähler, J1
Weiss, C1
Münzel, T1
Meinertz, T1
Freeman, BA1
Heitzer, T1
Kutala, VK1
Khan, M1
Mandal, R1
Potaraju, V1
Colantuono, G1
Kumbala, D1
Kuppusamy, P1
Santos, RD1
Nasir, K1
Orakzai, R1
Meneghelo, RS1
Carvalho, JA1
Blumenthal, RS1
Boĭko, EP1
Kaneva, AM2
Ovechkin, AO2
Potolitsyna, NN2
Boĭko, ER1
Boĭko, SG1
Kock, R1
Delvoux, B1
Sigmund, M1
Greiling, H1
Bardenheuer, HJ1
Fabry, A1
Höfling, B1
Peter, K1
Finelli, C2
Guarnieri, C2
Muscari, C2
Ventura, C1
Caldarera, CM2
Stefanelli, C1
Flamigni, F1
Fukuda, S1
Kuzuhara, K1
Dobashi, Y1
Aikawa, M1
Nishimori, H1
Inoue, S1
Otsubo, O1
Inou, T1
Mimura, N1
Komiyama, N1
Nakanishi, M1
Matuta, H1
Murata, H1
Hulsmann, WC1
Peschechera, A1
Serafini, F1
Ferrari, LE1
Togashi, R1
Koike, T1
Valkov, Y1
Kupatt, C1
Zahler, S1
Seligmann, C1
Massoudy, P1
Becker, BF1
Gerlach, E1
Yeung, PK1
Buckley, SJ1
Hung, OR1
Pollak, PT1
Barclay, KD1
Feng, JD1
Klassen, GA1
Smolenski, RT2
Jayakumar, J1
Seymour, AM1
Yacoub, MH2
Zych, M1
Makarewicz, W1
Mei, DA1
Nithipatikom, K1
Lasley, RD1
Gross, GJ1
Torun, M1
Yardim, S1
Simsek, B1
Burgaz, S1
Wisłowska, M1
Sypuła, S1
Kowalik, I1
Hoeper, MM1
Hohlfeld, JM1
Fabel, H1
Saito, D1
Shiraki, T1
Oka, T1
Kajiyama, A1
Doi, M1
Masaka, T1
Turgan, N1
Boydak, B1
Habif, S1
Gülter, C1
Senol, B1
Mutaf, I1
Ozmen, D1
Bayindir, O1
Fang, J1
Alderman, MH1
Domański, L1
Hosoya, T1
Rühle, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645]Phase 4100 participants (Anticipated)Interventional2018-12-01Not yet recruiting
Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases[NCT01248143]Phase 2/Phase 3300 participants (Actual)Interventional2010-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for uric acid and Myocardial Ischemia

ArticleYear
[Uric acid as a marker of pathophysiological mechanisms in patients with cardiovascular disease].
    Ugeskrift for laeger, 2005, Oct-03, Volume: 167, Issue:40

    Topics: Biomarkers; Cardiovascular Diseases; Heart Failure; Humans; Myocardial Ischemia; Prognosis; Uric Aci

2005
[Non-drug therapeutics of idiopathic hyperuricemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12

    Topics: Alcohol Drinking; Diet Therapy; Exercise Therapy; Humans; Microvascular Angina; Myocardial Ischemia;

1996
[Multiple risk factor syndrome and hyperuricemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2001, Sep-10, Volume: 90, Issue:9

    Topics: Female; Humans; Hyperlipidemias; Hypertension; Male; Myocardial Ischemia; Obesity; Risk Factors; Uri

2001
[Hyperuricemia and gout].
    Zeitschrift fur arztliche Fortbildung, 1992, Sep-25, Volume: 86, Issue:18

    Topics: Arthritis, Gouty; Energy Metabolism; Gout; Humans; Kidney Calculi; Myocardial Ischemia; Risk Factors

1992

Trials

5 trials available for uric acid and Myocardial Ischemia

ArticleYear
Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial.
    Lancet (London, England), 2022, 10-08, Volume: 400, Issue:10359

    Topics: Aged; Allopurinol; Coronary Artery Disease; Female; Gout; Humans; Male; Myocardial Infarction; Myoca

2022
Black tea reduces uric acid and C-reactive protein levels in humans susceptible to cardiovascular diseases.
    Toxicology, 2010, Nov-28, Volume: 278, Issue:1

    Topics: Adult; C-Reactive Protein; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Myocardial Is

2010
Clinical effects of enhanced external counterpulsation treatment in patients with ischemic heart failure.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Volume: 12, Issue:3

    Topics: Aged; Blood Pressure; Cohort Studies; Counterpulsation; Electrocardiography; Female; Heart Failure;

2012
[Endothelial protection in patients with apparent cardiac failure in long-term therapy by carvedilol].
    Klinicheskaia meditsina, 2003, Volume: 81, Issue:7

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Drug Therapy,

2003
[Cortisol levels in blood of persons with acute myocardial ischemia and myocardial infarction].
    Annales Academiae Medicae Stetinensis, 1999, Volume: 45

    Topics: Adult; Aged; Ascorbic Acid; Female; Free Radicals; Humans; Hydrocortisone; Leukocyte Count; Male; Ma

1999

Other Studies

42 other studies available for uric acid and Myocardial Ischemia

ArticleYear
Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:10

    Topics: Biomarkers; Class I Phosphatidylinositol 3-Kinases; Drugs, Chinese Herbal; Humans; Metabolomics; Mol

2022
Major adverse cardiovascular events and hyperuricemia during tuberculosis treatment.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Antitubercular Agents; Female; Humans; Hyperuricemia; Male; Myocardial Ischemia; Retrospective Studi

2023
Human concentrations of uric acid scavenges adaptive and maladaptive reactive oxygen species in isolated rat hearts subjected to ischemic stress.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:3

    Topics: Animals; Antioxidants; Humans; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mito

2020
Association between serum urate, gout and comorbidities: a case-control study using data from the UK Biobank.
    Rheumatology (Oxford, England), 2021, 07-01, Volume: 60, Issue:7

    Topics: Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Comorbidity; Diabetes Mellitus; Female;

2021
Close linkage between serum uric acid and cardiac dysfunction in patients with ischemic heart disease according to covariance structure analysis.
    Scientific reports, 2017, 05-30, Volume: 7, Issue:1

    Topics: Aged; Cardiac Catheterization; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial

2017
Uric acid levels and atrial fibrillation.
    Angiology, 2014, Volume: 65, Issue:2

    Topics: Atrial Fibrillation; Female; Heart Failure; Humans; Male; Myocardial Ischemia; Uric Acid

2014
Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts.
    BMJ (Clinical research ed.), 2013, Jul-18, Volume: 347

    Topics: Adult; Aged; Blood Pressure; Body Mass Index; Denmark; Female; Humans; Hyperuricemia; Male; Mendelia

2013
Response to the letter: uric acid levels and atrial fibrillation.
    Angiology, 2014, Volume: 65, Issue:2

    Topics: Atrial Fibrillation; Female; Heart Failure; Humans; Male; Myocardial Ischemia; Uric Acid

2014
Soluble ligand CD40 and uric acid as markers of atheromatosis in patients with obstructive sleep apnea.
    Advances in experimental medicine and biology, 2015, Volume: 839

    Topics: Adult; Atherosclerosis; Biomarkers; Case-Control Studies; CD40 Ligand; Female; Humans; Hypertension;

2015
Effect of serum uric acid on the positive predictive value of dobutamine stress echocardiography.
    Heart and vessels, 2016, Volume: 31, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Aged; Area Under Curve; Biomarkers; Chi-Square Distribution; Do

2016
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
    Journal of translational medicine, 2015, Mar-06, Volume: 13

    Topics: Administration, Oral; Allopurinol; Angiotensin II; Animals; Diet, High-Fat; Electrocardiography; Enz

2015
Different Contributions of Physical Activity on Arterial Stiffness between Diabetics and Non-Diabetics.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Age Factors; Aged; Ankle Brachial Index; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Exe

2016
The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure amd cholesterol.
    International heart journal, 2008, Volume: 49, Issue:6

    Topics: Age Factors; Aged; Blood Pressure; Cholesterol; Chronic Disease; Creatinine; Female; Heart Failure;

2008
Serum uric acid levels are associated with atrial fibrillation in patients with ischemic heart failure.
    Angiology, 2013, Volume: 64, Issue:4

    Topics: Aged; Atrial Fibrillation; Biomarkers; Chronic Disease; Female; Heart Atria; Heart Failure; Humans;

2013
Acetaminophen in the post-ischemia reperfused myocardium.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:11

    Topics: Acetaminophen; Animals; Creatine Kinase; Female; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myoc

2002
Selected risk factors of ischemic heart disease in Polish seafarers. Preliminary report.
    International maritime health, 2003, Volume: 54, Issue:1-4

    Topics: Adult; Age Distribution; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Me

2003
Serum uric acid and risk of death from cancer, cardiovascular disease or all causes in men.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2004, Volume: 11, Issue:3

    Topics: Adult; Age Factors; Aged; Diabetes Mellitus; Follow-Up Studies; Humans; Korea; Male; Middle Aged; Mu

2004
Clinical manifestations of patients with hyperuricemia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87 Suppl 2

    Topics: Age Distribution; Aged; Arthritis, Gouty; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans

2004
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy.
    Free radical biology & medicine, 2006, Oct-15, Volume: 41, Issue:8

    Topics: Aged; Cardiomyopathies; Cardiotonic Agents; Enzyme Inhibitors; Female; Humans; Hypoxanthine; Magneti

2006
Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:3

    Topics: Animals; Aspirin; Creatine Kinase; Cyclic N-Oxides; L-Lactate Dehydrogenase; Myocardial Ischemia; My

2006
Relation of uric acid levels to presence of coronary artery calcium detected by electron beam tomography in men free of symptomatic myocardial ischemia with versus without the metabolic syndrome.
    The American journal of cardiology, 2007, Jan-01, Volume: 99, Issue:1

    Topics: Brazil; Coronary Artery Disease; Cross-Sectional Studies; Humans; Male; Metabolic Syndrome; Middle A

2007
[Correlation of uric acid, APO-CIII, and apo-E in healthy individuals and patients with coronary heart disease and hypertensive disease].
    Klinicheskaia laboratornaia diagnostika, 2007, Issue:1

    Topics: Apolipoprotein C-III; Apolipoproteins E; Humans; Hypertension; Male; Myocardial Ischemia; Reference

2007
[Uric acid, apo-E and apo-C3 correlation in normo- and hyperlipidemia].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:12

    Topics: Adolescent; Adult; Aged; Apolipoprotein C-III; Apolipoproteins E; Biomarkers; Female; Humans; Hyperl

2007
A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1994, Volume: 32, Issue:11

    Topics: Adult; Allantoin; Creatine Kinase; Female; Humans; Hypoxanthine; Hypoxanthines; Isoenzymes; Male; My

1994
Adenosine: a sensitive marker of myocardial ischaemia in man.
    Cardiovascular research, 1994, Volume: 28, Issue:5

    Topics: Adenosine; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Circulation; Coronary Disease;

1994
Incorporation of [14C]hypoxanthine into cardiac adenine nucleotides: effect of aging and post-ischemic reperfusion.
    Biochimica et biophysica acta, 1993, Jan-22, Volume: 1180, Issue:3

    Topics: Adenine Nucleotides; Aging; Animals; Hypoxanthine; Hypoxanthines; Male; Myocardial Ischemia; Myocard

1993
Age-dependent differences of ATP breakdown and ATP-catabolite release in ischemic and reperfused hearts.
    Mechanisms of ageing and development, 1993, Volume: 67, Issue:1-2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aging; Animals; Energy Metabolism; In Vitro Technique

1993
[Study of several risk factors of ischemic heart disease in the last 17 years].
    [Nihon koshu eisei zasshi] Japanese journal of public health, 1993, Volume: 40, Issue:3

    Topics: Adult; Blood Glucose; Blood Pressure; Cholesterol; Humans; Male; Myocardial Ischemia; Risk Factors;

1993
Evaluation of cardiac function of renal transplant patients using stress and rest cardiac pool gated scintigraphy and myocardial scintigraphy with 99mTc-MIBI.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Adult; Age Factors; Aged; Contrast Media; Exercise Test; Female; Gated Blood-Pool Imaging; Heart; Hu

1996
Release of ischemia in paced rat Langendorff hearts by supply of L-carnitine: role of endogenous long-chain acylcarnitine.
    Molecular and cellular biochemistry, 1996, Mar-09, Volume: 156, Issue:1

    Topics: Aerobiosis; Animals; Cardiac Pacing, Artificial; Carnitine; Cations; Cell Membrane; Cells, Cultured;

1996
Computer classification of screening study of risk factor for ischemic heart disease in 20-60 year old subjects.
    Folia medica, 1996, Volume: 38, Issue:1

    Topics: Adult; Blood Glucose; Bulgaria; Computers; Electronic Data Processing; Female; Humans; Lipids; Male;

1996
Nitric oxide mitigates leukocyte adhesion and vascular leak after myocardial ischemia.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Catalase; Cell Adhesion; Cell Membrane Permeabili

1996
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:3

    Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine

1997
The effects of nucleotide pool on purine production in the postischemic heart.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; My

1998
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Is

1998
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:6

    Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; H

1998
Serum uric acid levels in cardiovascular diseases.
    Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:1

    Topics: Adult; Aged; Cardiovascular Diseases; Coronary Artery Disease; Female; Humans; Lipoproteins; Male; M

1998
Echocardiographic findings, 24-hour electrocardiographic Holter monitoring in patients with rheumatoid arthritis according to Steinbrocker's criteria, functional index, value of Waaler-Rose titre and duration of disease.
    Clinical rheumatology, 1998, Volume: 17, Issue:5

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Glucose; Echocardiography; Electrocardiography; Electrocar

1998
Hyperuricaemia in patients with right or left heart failure.
    The European respiratory journal, 1999, Volume: 13, Issue:3

    Topics: Adult; Aged; Arthritis, Gouty; Cardiomyopathy, Dilated; Diuretics; Female; Hemodynamics; Humans; Hyp

1999
Morphologic correlation between atherosclerotic lesions of the carotid and coronary arteries in patients with angina pectoris.
    Japanese circulation journal, 1999, Volume: 63, Issue:7

    Topics: Aged; Angina Pectoris; Arteriosclerosis; Blood Pressure; C-Reactive Protein; Carotid Artery Diseases

1999
Urinary hypoxanthine and xanthine levels in acute coronary syndromes.
    International journal of clinical & laboratory research, 1999, Volume: 29, Issue:4

    Topics: Acute Disease; Adult; Aged; Angina, Unstable; Biomarkers; Blood Urea Nitrogen; Creatine; Female; Hum

1999
Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey.
    JAMA, 2000, May-10, Volume: 283, Issue:18

    Topics: Adult; Aged; Analysis of Variance; Black or African American; Cardiovascular Diseases; Cross-Section

2000