Page last updated: 2024-10-20

uric acid and Myeloproliferative Disorders

uric acid has been researched along with Myeloproliferative Disorders in 18 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

Research Excerpts

ExcerptRelevanceReference
"Patients with myelofibrosis had echocardiographic evidence of PH more often than patients with other MPNs (p < 0."1.56Association of Disease Subtype and Duration with Echocardiographic Evidence of Pulmonary Hypertension in Myeloproliferative Neoplasm. ( Akgun-Cagliyan, G; Kaya, E; Kilic, O; Ozen, F; Senol, H; Yaylali, YT; Yilmaz, S, 2020)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199017 (94.44)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Yaylali, YT1
Yilmaz, S1
Akgun-Cagliyan, G1
Kilic, O1
Kaya, E1
Senol, H1
Ozen, F1
Sailer, D1
Yu, TF1
Boss, GR1
Seegmiller, JE2
Lozano-Tonkin, C2
Kay, NE1
Nelson, DA1
Gottlieb, AJ1
Catto, M1
Greul, W1
Kühböck, J1
Peskar, BM1
Vormittag, W1
Gilbert, HS1
Boyle, JA1
Ward, HP1
Block, MH1
Smith, LH1
Richter, R1
Hermanny, G1
Hofer, E1
Stobbe, H1
Frank, M1
Lazebnik, J1
De Vries, A1
Zucchelli, P1
Sasdelli, M1
Fusaroli, M1
Krakoff, IH1
Balis, ME1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Pulmonary Hypertension in Patients With Chronic Myeloproliferative Disorders at Sohag University Hospital[NCT04843475]150 participants (Anticipated)Observational2021-05-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for uric acid and Myeloproliferative Disorders

ArticleYear
[Etiology and risks of hyperuricemia].
    Medizinische Klinik, 1981, Feb-13, Volume: 76, Issue:4

    Topics: Alcoholism; Diuretics; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney Calculi;

1981
Hyperuricemia and gout. Classification, complications and management.
    The New England journal of medicine, 1979, Jun-28, Volume: 300, Issue:26

    Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human

1979
The spectrum of myeloproliferative disorders.
    The Medical clinics of North America, 1973, Volume: 57, Issue:2

    Topics: Blood Platelets; Cell Differentiation; Diagnosis, Differential; Hematocrit; Hematopoietic Stem Cells

1973
Aetiology of gout.
    Scottish medical journal, 1973, Volume: 18

    Topics: Allopurinol; Creatinine; Diet Therapy; Erythrocytes; Gout; Humans; Hypoxanthines; Lesch-Nyhan Syndro

1973
The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome.
    Medicine, 1971, Volume: 50, Issue:5

    Topics: Adrenal Cortex Hormones; Alkaline Phosphatase; Androgens; Anemia; Animals; Blood Cell Count; Blood C

1971

Other Studies

13 other studies available for uric acid and Myeloproliferative Disorders

ArticleYear
Association of Disease Subtype and Duration with Echocardiographic Evidence of Pulmonary Hypertension in Myeloproliferative Neoplasm.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2020, Volume: 29, Issue:5

    Topics: Adult; Aged; Bone Marrow Neoplasms; Echocardiography; Female; Humans; Hypertension, Pulmonary; Male;

2020
Urolithiasis in hyperuricemia and gout.
    The Journal of urology, 1981, Volume: 126, Issue:4

    Topics: Adult; Allopurinol; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Myelo

1981
[Nephrolithiasis within the framework of internal medicine (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Feb-22, Volume: 116, Issue:8

    Topics: Antineoplastic Agents; Cystine; Gout; Humans; Kidney Calculi; Lesch-Nyhan Syndrome; Myeloproliferati

1974
Eosinophilic Pelger-Huët anomaly with myeloproliferative disorder.
    American journal of clinical pathology, 1973, Volume: 60, Issue:5

    Topics: Aged; Eosinophilia; Eosinophils; Hepatomegaly; Histocytochemistry; Humans; Inclusion Bodies; Leukocy

1973
Pathology of gout.
    Scottish medical journal, 1973, Volume: 18

    Topics: Allopurinol; Arthritis; Calcium Phosphates; Cartilage, Articular; Chondrocalcinosis; Crystallization

1973
[Hypercalcaemic crisis as primary manifestation of acute leukaemia in an adult (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Feb-15, Volume: 99, Issue:7

    Topics: Blood Cell Count; Blood Urea Nitrogen; Bone Marrow Examination; Bone Resorption; Creatinine; Cycloph

1974
[A "myeloproliferative syndrome" of long duration (author's transl)].
    Medizinische Klinik, 1974, Mar-08, Volume: 69, Issue:10

    Topics: Aged; Arthritis; Bone Marrow; Chronic Disease; Diagnosis, Differential; Humans; Leukemia, Myeloid; M

1974
The diagnosis and treatment of metabolic stone disease.
    The Medical clinics of North America, 1972, Volume: 56, Issue:4

    Topics: Acidosis, Renal Tubular; Age Factors; Calcium; Cystinuria; Humans; Hypercalcemia; Intestinal Disease

1972
[Secondary hyperuricemia in hemoblastosis].
    Das Deutsche Gesundheitswesen, 1971, Nov-04, Volume: 26, Issue:45

    Topics: Blood Cell Count; Humans; Leukemia; Myeloproliferative Disorders; Nephrosis; Polycythemia Vera; Prim

1971
Metabolic aberrations in gout.
    Clinical orthopaedics and related research, 1970, Volume: 71

    Topics: Female; Glycogen Storage Disease Type I; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; Male

1970
Uric acid lithiasis--a study of six hundred and twenty-two patients.
    Urologia internationalis, 1970, Volume: 25, Issue:1

    Topics: Adult; Ethnicity; Female; Gout; Humans; Hyperparathyroidism; Israel; Male; Myeloproliferative Disord

1970
[Allopurinol: its clinical use].
    Giornale di clinica medica, 1968, Volume: 49, Issue:10

    Topics: Adult; Aged; Allopurinol; Child; Diuretics; Female; Gout; Humans; Kidney Diseases; Kidney Failure, C

1968
Allopurinol in the prevention of hyperuricaemia secondary to the treatment of neoplastic diseases with alkylating agents, adrenal steroids, and radiation therapy.
    Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6 Suppl

    Topics: Adult; Allopurinol; Carbon Isotopes; Child; Cyclophosphamide; Enzyme Therapy; Female; Humans; Hydroc

1966