uric acid has been researched along with Muscle Contraction in 17 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Authors present a therapeutic trial with allopurinol on Duchenne muscular dystrophy." | 9.05 | [Therapeutic trial with allopurinol in progressive muscular dystrophy (author's transl)]. ( Alvarez, M; Campistol, J; Fábregues, I; Fernández Alvarez, E; Pineda, M, 1982) |
| "Authors present a therapeutic trial with allopurinol on Duchenne muscular dystrophy." | 5.05 | [Therapeutic trial with allopurinol in progressive muscular dystrophy (author's transl)]. ( Alvarez, M; Campistol, J; Fábregues, I; Fernández Alvarez, E; Pineda, M, 1982) |
| " Surface electromyograms were used to evaluate the muscle spasm theory; the possibility of actual muscle cell damage was monitored by the presence of myoglobinuria, while the ratio of hydroxyproline/creatinine (OHP/Cr) in 24 hr urine collection was used as a marker for connective tissue involvement." | 3.65 | Factors in delayed muscle soreness. ( Abraham, WM, 1977) |
| "Allopurinol treatment reduced XO activity to 5% of the basal levels (P < 0." | 1.39 | Xanthine oxidase inhibition attenuates skeletal muscle signaling following acute exercise but does not impair mitochondrial adaptations to endurance training. ( Hiam, DS; McConell, GK; Nicolas, MA; Wadley, GD, 2013) |
| "Hypertension is associated with endothelial dysfunction." | 1.36 | Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats. ( Szasz, T; Watts, SW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wadley, GD | 1 |
| Nicolas, MA | 1 |
| Hiam, DS | 1 |
| McConell, GK | 1 |
| Whidden, MA | 1 |
| McClung, JM | 1 |
| Falk, DJ | 1 |
| Hudson, MB | 1 |
| Smuder, AJ | 1 |
| Nelson, WB | 1 |
| Powers, SK | 1 |
| Szasz, T | 1 |
| Watts, SW | 1 |
| Shils, ME | 1 |
| Nikolaidis, MG | 1 |
| Paschalis, V | 1 |
| Giakas, G | 1 |
| Fatouros, IG | 1 |
| Koutedakis, Y | 1 |
| Kouretas, D | 1 |
| Jamurtas, AZ | 1 |
| Pineda, M | 1 |
| Fábregues, I | 1 |
| Campistol, J | 1 |
| Fernández Alvarez, E | 1 |
| Alvarez, M | 1 |
| Deby, C | 1 |
| Deby-Dupont, G | 1 |
| Kulakowski, S | 1 |
| Renoirte, P | 1 |
| de Bruyn, CH | 1 |
| Majumdar, R | 1 |
| Cwik, VA | 1 |
| Solonynko, G | 1 |
| Brooke, MH | 1 |
| Thomson, WH | 1 |
| Smith, I | 1 |
| Knochel, JP | 1 |
| Carter, NW | 1 |
| Williams, JF | 1 |
| Lowitt, S | 1 |
| Polson, JB | 1 |
| Szentivanyi, A | 1 |
| Abraham, WM | 1 |
| Bangsbo, J | 1 |
| Sjödin, B | 1 |
| Hellsten-Westing, Y | 1 |
| Webster, DR | 1 |
| Boston, GD | 1 |
| Paton, DM | 1 |
| Suzuki, Y | 1 |
| Ito, M | 1 |
| Hayashi, M | 1 |
| Yomagemi, I | 1 |
| Roussan, MS | 1 |
| Gordon, S | 1 |
2 trials available for uric acid and Muscle Contraction
| Article | Year |
|---|---|
[Therapeutic trial with allopurinol in progressive muscular dystrophy (author's transl)].
Topics: Adolescent; Allopurinol; Child; Child, Preschool; Clinical Trials as Topic; Creatine Kinase; Double- | 1982 |
X-linked recessive (Duchenne) muscular dystrophy (DMD) and purine metabolism: effects of oral allopurinol and adenylate.
Topics: Adenosine Monophosphate; Administration, Oral; Adolescent; Allopurinol; Child; Child, Preschool; Cli | 1978 |
15 other studies available for uric acid and Muscle Contraction
| Article | Year |
|---|---|
Xanthine oxidase inhibition attenuates skeletal muscle signaling following acute exercise but does not impair mitochondrial adaptations to endurance training.
Topics: Adaptation, Physiological; Allopurinol; Animals; Enzyme Inhibitors; Glucose Transporter Type 4; Male | 2013 |
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction.
Topics: Animals; Diaphragm; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Hypoxan | 2009 |
Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Blotting, Western; Desoxycorticosterone; Endo | 2010 |
EXPERIMENTAL HUMAN MAGNESIUM DEPLETION. I. CLINICAL OBSERVATIONS AND BLOOD CHEMISTRY ALTERATIONS.
Topics: Biomedical Research; Blood Chemical Analysis; Calcium; Calcium, Dietary; Cholesterol; Electromyograp | 1964 |
Decreased blood oxidative stress after repeated muscle-damaging exercise.
Topics: Adult; Area Under Curve; Bilirubin; Biomarkers; Exercise; Female; Glutathione; Greece; Humans; Leg; | 2007 |
Natural factors modulating the intervention of activated oxygen in the biosynthesis of prostanoids.
Topics: Animals; Arachidonic Acids; Blood Pressure; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; | 1981 |
Dynamometric and biochemical observations in Duchenne patients receiving allopurinol.
Topics: Adenine; Allopurinol; Child; Creatine Kinase; Erythrocytes; Humans; Muscle Contraction; Muscular Dys | 1981 |
Relationship of oxypurine release to contractile failure in dinitrophenol-treated rat skeletal muscle.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Dinitrophenols; Hypoxanthine; Hypoxanthines; In | 1993 |
The role of muscle cell injury in the pathogenesis of acute renal failure after exercise.
Topics: Acute Kidney Injury; Adenosine Triphosphatases; Aldosterone; Animals; Creatine Kinase; Dogs; Hot Tem | 1976 |
Pharmacological and biochemical activities of some monomethylxanthine and methyluric acid derivatives of theophylline and caffeine.
Topics: Animals; Caffeine; Dogs; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smoot | 1978 |
Factors in delayed muscle soreness.
Topics: Adult; Creatinine; Electromyography; Evoked Potentials; Female; Heart Rate; Humans; Hydroxyproline; | 1977 |
Exchange of hypoxanthine in muscle during intense exercise in man.
Topics: Biological Transport, Active; Exercise; Humans; Hypoxanthine; Hypoxanthines; Muscle Contraction; Mus | 1992 |
Mechanism of urate production by guinea-pig ileum.
Topics: Adenosine Deaminase Inhibitors; Animals; Biological Transport; Coformycin; Female; Guanosine; Guinea | 1986 |
[Pharmacological studies of a new analgesic agent, 2-phenyl-4-dimethylaminopropylamino-6-ethoxy-3(2H)pyridazinone hydrochloride (TM-3)].
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Blood Pressure; Depress | 1972 |
Effect of a new antispasticity drug on neurogenic bladder function: preliminary report.
Topics: Adult; Aminobutyrates; Benzene Derivatives; Female; Humans; Male; Middle Aged; Multiple Sclerosis; M | 1973 |