Page last updated: 2024-10-20

uric acid and Movement Disorders

uric acid has been researched along with Movement Disorders in 18 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"In contrast, at complete HPRT deficiency, besides overproduction of uric acid neurological problems appear including spasticity, choreoathetosis, mental retardation, and compulsive self-mutilation."1.32The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis. ( Mitev, VI; Neychev, VK, 2004)
"Caffeine alone did not produce any significant modification in functional impairment but the co-administration significantly increased the effect of naproxen."1.29Usefulness of the pain-induced functional impairment model to relate plasma levels of analgesics to their efficacy in rats. ( Hoyo-Vadillo, C; López-Munoz, FJ; Pérez-Urizar, J, 1995)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Lee, HF1
Hsu, CC1
Chi, CS1
Tsai, CR1
Yu, Z1
Zhang, S1
Wang, D1
Fan, M1
Gao, F1
Sun, W1
Li, Z1
Li, S1
Neychev, VK1
Mitev, VI1
Howard, RS1
Walzak, MP1
Hoyo-Vadillo, C1
Pérez-Urizar, J1
López-Munoz, FJ1
van der Zee, SP3
Schretlen, ED3
Monnens, LA2
Watts, RW1
McKeran, RO1
Brown, E1
Andrews, TM1
Griffiths, MI1
Proctor, P1
Barbeau, A1
Mars, H1
Gillo-Joffroy, L1
Storey, B1
Refsum, S1
Lommen, EJ1
Trijbels, JM1
Ghadimi, H1
Bhalla, CK1
Kirchenbaum, DM1
Frost, P1
Weinstein, GD1
Nyhan, WL2
Dodge, PR1

Reviews

1 review available for uric acid and Movement Disorders

ArticleYear
The significance of uric acid in the diagnosis and treatment of Parkinson disease: An updated systemic review.
    Medicine, 2017, Volume: 96, Issue:45

    Topics: Age Factors; Biomarkers; Disease Progression; Humans; Hyperuricemia; Movement Disorders; Oxidative S

2017

Other Studies

17 other studies available for uric acid and Movement Disorders

ArticleYear
Genotype-Phenotype Dissociation in Two Taiwanese Children with Molybdenum Cofactor Deficiency Caused by MOCS2 Mutation.
    Neuropediatrics, 2022, Volume: 53, Issue:3

    Topics: Child; Homozygote; Humans; Magnetic Resonance Imaging; Metal Metabolism, Inborn Errors; Movement Dis

2022
The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis.
    Medical hypotheses, 2004, Volume: 63, Issue:1

    Topics: Animals; Biochemistry; Brain; Humans; Hypoxanthine Phosphoribosyltransferase; Intellectual Disabilit

2004
A new cause for uric acid stones in childhood.
    The Journal of urology, 1967, Volume: 98, Issue:5

    Topics: Child, Preschool; Humans; Intellectual Disability; Kidney Calculi; Male; Movement Disorders; Self Mu

1967
Usefulness of the pain-induced functional impairment model to relate plasma levels of analgesics to their efficacy in rats.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:6

    Topics: Analgesics; Animals; Caffeine; Drug Interactions; Female; Movement Disorders; Naproxen; Pain Measure

1995
Megaloblastic anaemia in the Lesch-Nyhan syndrome.
    Lancet (London, England), 1968, Jun-29, Volume: 1, Issue:7557

    Topics: Adenine; Anemia, Macrocytic; Cerebral Palsy; Child; Humans; Intellectual Disability; Male; Movement

1968
Hyperuricemia. Case presentation.
    The Journal of the Arkansas Medical Society, 1971, Volume: 68, Issue:7

    Topics: Adolescent; Adult; Athetosis; Child; Child, Preschool; Diagnosis, Differential; Fibroblasts; Humans;

1971
Clinical and biochemical studies on treatment of Lesch-Nyhan syndrome.
    Archives of disease in childhood, 1974, Volume: 49, Issue:9

    Topics: Adenine; Allopurinol; Body Weight; Child, Preschool; Chlorpromazine; Creatinine; Exchange Transfusio

1974
Electron-transfer factors in psychosis and dyskinesia.
    Physiological chemistry and physics, 1972, Volume: 4, Issue:4

    Topics: Blood Proteins; Bromides; Dihydroxyphenylalanine; Electron Transport; Epinephrine; Humans; Iron; Lip

1972
Adverse clinical side effects of levodopa therapy.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede

1971
The Lesch-Nyhan syndrome.
    The Medical journal of Australia, 1969, Oct-04, Volume: 2, Issue:14

    Topics: Child, Preschool; Humans; Infant Nutrition Disorders; Intellectual Disability; Male; Movement Disord

1969
[Inborn hyperuricemia--an anomaly of uric acid metabolism in connection with psychomotor retardation, involuntary movements and self mutilation, Lesch-Nyhan syndrome].
    Nordisk medicin, 1970, Jan-08, Volume: 83, Issue:2

    Topics: Adolescent; Adult; Age Factors; Allopurinol; Child; Child, Preschool; Humans; Infant; Infant, Newbor

1970
The influence of adenine on the clinical features and purine metabolism in the Lesch-Nyhan syndrome.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:3

    Topics: Adenine; Allopurinol; Athetosis; Bone Marrow; Carbon Isotopes; Child; Child, Preschool; Chorea; Comp

1970
The significance of the deficiency state in Lesch-Nyhan disease.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:3

    Topics: Allopurinol; Amino Acids; Athetosis; Carbon Isotopes; Child, Preschool; Chorea; Compulsive Behavior;

1970
Diagnosis of Lesch-Nyhan syndrome by direct study of skin specimens.
    JAMA, 1970, Apr-13, Volume: 212, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Child; Clinical Enzyme Tests; Erythrocytes; Female; Fibroblasts; G

1970
[A hereditary disorder of purine metabolism with a cerebral affection and megaloblastic anemia (Lesch-Nyhan syndrome)].
    Nederlands tijdschrift voor geneeskunde, 1968, Aug-17, Volume: 112, Issue:33

    Topics: Anemia, Macrocytic; Athetosis; Bone Marrow Examination; Child, Preschool; Humans; Infant; Male; Meta

1968
A disorder of uric acid metabolism and cerebral function in childhood.
    Arthritis and rheumatism, 1965, Volume: 8, Issue:5

    Topics: Central Nervous System Diseases; Child; Child, Preschool; Fingers; Humans; Infant; Intellectual Disa

1965
Disordered uric acid metabolism and neurologic abnormalities.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:1

    Topics: Blood-Brain Barrier; Cerebral Palsy; Humans; Infant; Intellectual Disability; Male; Movement Disorde

1966