Page last updated: 2024-10-20

uric acid and Metabolically Benign Obesity

uric acid has been researched along with Metabolically Benign Obesity in 8 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
" In the stratified analysis by uric acid levels, the prevalence of NAFLD was significantly higher in participants with MHO, MUNW, and MUO in the hyperuricemia group than those in the normal uric acid group, and the interaction effect of metabolic phenotypes and uric acid on NAFLD was statistical significant (P < 0."4.31Hyperuricemia as an effect modifier of the association between metabolic phenotypes and nonalcoholic fatty liver disease in Chinese population. ( Li, X; Miao, Y; Zhang, Q; Zhang, Y; Zheng, J, 2023)
" Our aim was to identify the frequency of MHO in obese subjects, to assess the potential associations of demographic characteristics, serum uric acid, alanine transaminase (ALT), pediatric nonalcoholic fatty liver disease fibsosis score probability (PNFS p) with MHO status and to evaluate the differences between MHO and metabolically unhealthy obesity (MUO) with regard to metabolic syndrome surrogates."4.31Comparative analyses of surrogates of metabolic syndrome in children and adolescents with metabolically healthy obesity vs. metabolically unhealthy obesity according to Damanhoury's criteria. ( Ada, Hİ; Cakir, AD; Mohamad, R; Uçar, A, 2023)
" We also tested whether the addition of an insulin resistance index (HOMA-index >90th percentile by sex and age) and the presence of hyperuricemia (serum uric acid >90th percentile by sex and age) to the definition of MUO better identified obese children with early cardiac damage."4.12Association of obesity phenotypes with left ventricular mass index and left ventricular hypertrophy in children and adolescents. ( Antolini, L; Genovesi, S; Giussani, M; Lieti, G; Montemerlo, M; Orlando, A; Parati, G; Patti, I; Tassistro, E, 2022)
"In a multi-center study (n=2495), we used unsupervised machine learning to cluster patients with obesity from Shanghai Tenth People's hospital (n=882, main cohort) based on three clinical variables (AUCs of glucose and of insulin during OGTT, and uric acid)."4.02Machine Learning to Identify Metabolic Subtypes of Obesity: A Multi-Center Study. ( Arefan, D; Cheng, X; Du, L; Feng, W; Gao, L; Lin, Z; Liu, Y; Ma, C; Qu, S; Wu, S; You, H; Yu, J; Zhou, D; Zhu, D; Zhu, J, 2021)
" Uric acid concentration associated with metabolic health when abdominal obesity was excluded."3.85Impact of dietary intake, lifestyle and biochemical factors on metabolic health in obese adolescents. ( Aldhoon-Hainerová, I; Hainer, V; Zamrazilová, H, 2017)
"Hyperuricemia was defined as SUA ≥7mg/dl (420mmol/L) in men or ≥6mg/dl (360mmol/L) in women."1.43Metabolically healthy obesity also has risk for hyperuricemia among Chinese general population: A cross-sectional study. ( Chen, Y; Guo, X; Sun, G; Sun, Y; Yang, H; Yu, S; Zhang, N; Zheng, L, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's5 (62.50)2.80

Authors

AuthorsStudies
Cho, AY1
Roh, JG1
Shim, YS1
Lee, HS1
Hwang, JS1
Genovesi, S1
Tassistro, E1
Giussani, M1
Lieti, G1
Patti, I1
Orlando, A1
Montemerlo, M1
Antolini, L1
Parati, G1
Zheng, J1
Li, X1
Zhang, Y1
Miao, Y1
Zhang, Q1
Mohamad, R1
Cakir, AD1
Ada, Hİ1
Uçar, A1
Lin, Z1
Feng, W1
Liu, Y1
Ma, C1
Arefan, D1
Zhou, D1
Cheng, X1
Yu, J1
Gao, L1
Du, L1
You, H1
Zhu, J1
Zhu, D1
Wu, S1
Qu, S1
Aldhoon-Hainerová, I1
Hainer, V1
Zamrazilová, H1
De Pergola, G1
Giagulli, VA1
Bartolomeo, N1
Gaeta, F1
Petruzzella, A1
Guastamacchia, E1
Triggiani, V1
Silvestris, F1
Chen, Y1
Zhang, N1
Sun, G1
Guo, X1
Yu, S1
Yang, H1
Zheng, L1
Sun, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Data-driven Clustering for Metabolic Classification of Obesity Using Machine Learning[NCT04282837]2,495 participants (Actual)Observational2020-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for uric acid and Metabolically Benign Obesity

ArticleYear
Biochemical predictors of metabolically unhealthy obesity in children and adolescents.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Jan-27, Volume: 35, Issue:1

    Topics: Adolescent; Child; Female; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Obesity, Metabo

2022
Association of obesity phenotypes with left ventricular mass index and left ventricular hypertrophy in children and adolescents.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Child; Female; Humans; Hypertrophy, Left Ventricular; Hyperuricemia; Insulin Resistance; Male; Metab

2022
Hyperuricemia as an effect modifier of the association between metabolic phenotypes and nonalcoholic fatty liver disease in Chinese population.
    Journal of translational medicine, 2023, 01-21, Volume: 21, Issue:1

    Topics: Body Mass Index; East Asian People; Humans; Hyperuricemia; Metabolic Syndrome; Non-alcoholic Fatty L

2023
Comparative analyses of surrogates of metabolic syndrome in children and adolescents with metabolically healthy obesity vs. metabolically unhealthy obesity according to Damanhoury's criteria.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, May-25, Volume: 36, Issue:5

    Topics: Body Mass Index; Child; Female; Humans; Hyperuricemia; Metabolic Syndrome; Obesity, Metabolically Be

2023
Machine Learning to Identify Metabolic Subtypes of Obesity: A Multi-Center Study.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; Blood Glucose; Body Mass Index; China; Comorbidity; Female; Glucose Tolerance Test; Humans; H

2021
Impact of dietary intake, lifestyle and biochemical factors on metabolic health in obese adolescents.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:8

    Topics: Adolescent; Alanine Transaminase; Biomarkers; C-Reactive Protein; Czech Republic; Diet; Diet, Health

2017
Independent Relationship between Serum Osteocalcin and Uric Acid in a Cohort of Apparently Healthy Obese Subjects.
    Endocrine, metabolic & immune disorders drug targets, 2017, Volume: 17, Issue:3

    Topics: Adult; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Female; Health Status; Humans; Li

2017
Metabolically healthy obesity also has risk for hyperuricemia among Chinese general population: A cross-sectional study.
    Obesity research & clinical practice, 2016, Volume: 10 Suppl 1

    Topics: Adult; Aged; Body Mass Index; China; Cross-Sectional Studies; Female; Health Status; Humans; Hyperur

2016