uric acid has been researched along with Malaria, Falciparum in 8 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the influence of Plasmodium falciparum malaria on plasma antioxidants and lipid peroxidation, plasma ascorbate, urate, total protein and albumin, ceruloplasmin and malondialdehyde (MDA) were determined in two groups of 42 patients each, one with mild and the other with severe falciparum malaria, and in an equal number of age- and sex-matched control subjects." | 3.68 | Plasma antioxidants and lipid peroxidation products in falciparum malaria. ( Bose, TK; Das, BS; Mishra, SK; Mohanty, D; Mohanty, S; Patnaik, JK; Satpathy, SK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bhardwaj, N | 1 |
| Ahmed, MZ | 1 |
| Sharma, S | 1 |
| Srivastava, B | 1 |
| Pande, V | 1 |
| Anvikar, AR | 1 |
| van de Hoef, DL | 3 |
| Coppens, I | 1 |
| Holowka, T | 1 |
| Ben Mamoun, C | 1 |
| Branch, O | 1 |
| Rodriguez, A | 3 |
| Bertrand, KE | 1 |
| Mathieu, N | 1 |
| Inocent, G | 1 |
| Honore, FK | 1 |
| Griffith, JW | 1 |
| Sun, T | 1 |
| McIntosh, MT | 1 |
| Bucala, R | 1 |
| Lopera-Mesa, TM | 2 |
| Mita-Mendoza, NK | 2 |
| Doumbia, S | 2 |
| Konaté, D | 2 |
| Doumbouya, M | 2 |
| Gu, W | 2 |
| Traoré, K | 1 |
| Diakité, SA | 1 |
| Remaley, AT | 1 |
| Anderson, JM | 2 |
| Fay, MP | 2 |
| Long, CA | 2 |
| Diakité, M | 2 |
| Fairhurst, RM | 2 |
| Santos-Argumedo, L | 1 |
| Iwalokun, BA | 1 |
| Bamiro, SB | 1 |
| Ogunledun, A | 1 |
| Das, BS | 1 |
| Patnaik, JK | 1 |
| Mohanty, S | 1 |
| Mishra, SK | 1 |
| Mohanty, D | 1 |
| Satpathy, SK | 1 |
| Bose, TK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Studies of Innate and Acquired Resistance to P. Falciparum Malaria in Mali[NCT00669084] | 1,718 participants (Actual) | Observational | 2008-04-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for uric acid and Malaria, Falciparum
| Article | Year |
|---|---|
Clinicopathological study of potential biomarkers of Plasmodium falciparum malaria severity and complications.
Topics: Adolescent; Adult; Bilirubin; Biomarkers; Case-Control Studies; Caveolin 1; Child; Early Diagnosis; | 2020 |
Plasmodium falciparum-derived uric acid precipitates induce maturation of dendritic cells.
Topics: Cell Communication; Dendritic Cells; Erythrocytes; Fluorescent Antibody Technique; Humans; Inflammat | 2013 |
Antioxidant status of bilirubin and uric acid in patients diagnosed with Plasmodium falciparum malaria in Douala.
Topics: Adolescent; Adult; Aged; Animals; Antioxidants; Bilirubin; Cameroon; Female; Humans; Malaria, Falcip | 2008 |
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid.
Topics: Allopurinol; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Protei | 2009 |
Plasma uric acid levels correlate with inflammation and disease severity in Malian children with Plasmodium falciparum malaria.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Cytokines; Humans; Inflammation; Inflammation Media | 2012 |
A potential role for plasma uric acid in the endothelial pathology of Plasmodium falciparum malaria.
Topics: E-Selectin; Endothelium; Erythrocytes; Fibrin; Humans; Inflammation; Intercellular Adhesion Molecule | 2013 |
Levels and interactions of plasma xanthine oxidase, catalase and liver function parameters in Nigerian children with Plasmodium falciparum infection.
Topics: Adolescent; Alanine Transaminase; Animals; Aspartate Aminotransferase, Mitochondrial; Bilirubin; Cat | 2006 |
Plasma antioxidants and lipid peroxidation products in falciparum malaria.
Topics: Analysis of Variance; Ascorbic Acid; Bilirubin; Blood Proteins; Ceruloplasmin; Cholesterol; Hemoglob | 1993 |