uric acid has been researched along with Lymphoma, Non-Hodgkin in 40 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Comparing the data of a subgroup of 12 patients receiving rasburicase with that of a historic cohort of 14 patients treated with allopurinol indicated the superiority of rasburicase over allopurinol in prophylaxis and treatment of hyperuricemia in children with leukemia and lymphoma." | 5.12 | Prevention and treatment of hyperuricemia with rasburicase in children with leukemia and non-Hodgkin's lymphoma. ( Bárdi, E; Bartyik, K; Galántai, I; Kajtár, P; Kiss, C; Kovács, G; Masát, P; Nagy, K; Rényi, I; Udvardi, E, 2007) |
| " The primary objective was to assess the safety of rasburicase by the incidence of adverse events (AEs)." | 3.30 | Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin's Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study. ( Chen, Y; Fang, J; Gao, J; He, Y; Liu, R; Shen, S; Sun, J; Tang, Y; Wang, T; Wu, X; Zhang, H; Zhang, J; Zhang, M; Zhu, X, 2023) |
| "Dexrazoxane has in vitro antioxidant capacity." | 2.75 | In vitro and in vivo study on the antioxidant activity of dexrazoxane. ( Antonelli, A; Carpi, A; Cervetti, G; Fallahi, P; Franzoni, F; Galetta, F; Petrini, M; Regoli, F; Santoro, G; Tocchini, L, 2010) |
| "Hyperuricemia and tumor lysis syndrome are well-known complications during induction treatment of aggressive non-Hodgkin's lymphomas (NHLs)." | 2.71 | Efficacy and safety of rasburicase (recombinant urate oxidase) for the prevention and treatment of hyperuricemia during induction chemotherapy of aggressive non-Hodgkin's lymphoma: results of the GRAAL1 (Groupe d'Etude des Lymphomes de l'Adulte Trial on R ( Belhadj, K; Bologna, S; Casasnovas, O; Christian, B; Coiffier, B; Fermé, C; Herbrecht, R; Jourdan, E; Mounier, N; Sonet, A; Tilly, H, 2003) |
| "The relationship between acute lymphoblastic leukemia (ALL-L3) and stage IV small noncleaved cell lymphoma with bone marrow involvement (SNCL) was analyzed by retrospective study of 45 patients." | 1.29 | L3 acute lymphoblastic leukemia. Comparison with small noncleaved cell lymphoma involving the bone marrow. ( Arthur, DC; Brunning, R; Dayton, VD; Gajl-Peczalska, KJ, 1994) |
| "Seemingly, dogs with uncomplicated lymphosarcoma rarely have renal dysfunction or clinically important alterations in uric acid or phosphorus excretion secondary to rapid tumor lysis." | 1.27 | Uric acid and phosphorus excretion in dogs with lymphosarcoma. ( Leifer, CE; Matus, RE; Page, RL, 1986) |
| "Twenty-three patients had Burkitt lymphoma, 3 had non-Burkitt undifferentiated lymphoma and 7 had lymphoblastic lymphoma." | 1.26 | Renal and metabolic complications of undifferentiated and lymphoblastic lymphomas. ( Balow, JE; Magrath, IT; Spiegel, RJ; Tsokos, GC, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (60.00) | 18.7374 |
| 1990's | 7 (17.50) | 18.2507 |
| 2000's | 5 (12.50) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Farooqui, N | 1 |
| Sy-Go, JPT | 1 |
| Miao, J | 1 |
| Mehta, R | 1 |
| Vaughan, LE | 1 |
| Bennani, NN | 1 |
| Wang, Y | 1 |
| Bansal, R | 1 |
| Hathcock, MA | 1 |
| Hayman, SR | 1 |
| Johnston, PB | 1 |
| Villasboas, JC | 1 |
| Paludo, J | 1 |
| Ansell, SM | 1 |
| Leung, N | 1 |
| Lin, Y | 1 |
| Herrmann, SM | 1 |
| Majumdar, S | 1 |
| Sharma, N | 1 |
| Sengar, M | 1 |
| Thorat, J | 1 |
| Nayak, L | 1 |
| Bonda, A | 1 |
| Bagal, B | 1 |
| Rajendra, A | 1 |
| Sethi, A | 1 |
| Jain, H | 1 |
| Wang, T | 1 |
| Zhu, X | 1 |
| Chen, Y | 1 |
| Shen, S | 1 |
| Tang, Y | 1 |
| Zhang, J | 1 |
| He, Y | 1 |
| Zhang, H | 1 |
| Gao, J | 1 |
| Fang, J | 1 |
| Liu, R | 1 |
| Wu, X | 1 |
| Sun, J | 1 |
| Zhang, M | 1 |
| Galetta, F | 1 |
| Franzoni, F | 1 |
| Cervetti, G | 1 |
| Regoli, F | 1 |
| Fallahi, P | 1 |
| Tocchini, L | 1 |
| Carpi, A | 1 |
| Antonelli, A | 1 |
| Petrini, M | 1 |
| Santoro, G | 1 |
| Lim, E | 1 |
| Bennett, P | 1 |
| Beilby, J | 1 |
| FISHER, MS | 1 |
| TORRE, AV | 1 |
| WOHL, GT | 1 |
| GREENBAUM, D | 1 |
| STONE, HF | 1 |
| WINKLER, JW | 1 |
| CONOLLY, ME | 1 |
| ELLIS, H | 1 |
| WATKIN, DM | 1 |
| STEINFELD, JL | 1 |
| MITCHELL, G | 1 |
| WILDEN, BJ | 1 |
| DIXON, P | 1 |
| KRAKOFF, IH | 1 |
| MEYER, RL | 1 |
| Coiffier, B | 1 |
| Mounier, N | 1 |
| Bologna, S | 1 |
| Fermé, C | 1 |
| Tilly, H | 1 |
| Sonet, A | 1 |
| Christian, B | 1 |
| Casasnovas, O | 1 |
| Jourdan, E | 1 |
| Belhadj, K | 1 |
| Herbrecht, R | 1 |
| Wang, LY | 1 |
| Shih, LY | 1 |
| Chang, H | 1 |
| Jou, ST | 1 |
| Lin, KH | 1 |
| Yeh, TC | 1 |
| Lin, SF | 1 |
| Liang, DC | 1 |
| Rényi, I | 1 |
| Bárdi, E | 1 |
| Udvardi, E | 1 |
| Kovács, G | 1 |
| Bartyik, K | 1 |
| Kajtár, P | 1 |
| Masát, P | 1 |
| Nagy, K | 1 |
| Galántai, I | 1 |
| Kiss, C | 1 |
| Tsokos, GC | 1 |
| Balow, JE | 1 |
| Spiegel, RJ | 1 |
| Magrath, IT | 1 |
| Dayton, VD | 1 |
| Arthur, DC | 1 |
| Gajl-Peczalska, KJ | 1 |
| Brunning, R | 1 |
| Hande, KR | 1 |
| Garrow, GC | 1 |
| Pui, CH | 2 |
| Relling, MV | 2 |
| Lascombes, F | 1 |
| Harrison, PL | 1 |
| Struxiano, A | 1 |
| Mondesir, JM | 1 |
| Ribeiro, RC | 1 |
| Sandlund, JT | 1 |
| Rivera, GK | 1 |
| Evans, WE | 1 |
| Mahmoud, HH | 2 |
| Ten Harkel, AD | 1 |
| Kist-Van Holthe, JE | 1 |
| Van Weel, M | 1 |
| Van der Vorst, MM | 1 |
| Leach, M | 1 |
| Parsons, RM | 1 |
| Reilly, JT | 1 |
| Winfield, DA | 1 |
| Pérez Encinas, M | 1 |
| Bello, JL | 1 |
| Bendaña, A | 1 |
| Rabuñal, MJ | 1 |
| González, S | 1 |
| Abuín, I | 1 |
| Noya, M | 1 |
| Cadarso, C | 1 |
| Wiley, JM | 1 |
| Woods, GM | 1 |
| Leverger, G | 1 |
| Camitta, B | 1 |
| Hastings, C | 1 |
| Blaney, SM | 1 |
| Reaman, GH | 1 |
| Mine, H | 1 |
| Shibuya, H | 1 |
| Matsubara, S | 1 |
| Horiuchi, J | 1 |
| Suenaga, M | 1 |
| Málaga, S | 1 |
| Bayón, JM | 1 |
| Matesanz, JL | 1 |
| Crespo, M | 1 |
| Poddubnaia, IV | 1 |
| Mansurov, AN | 1 |
| Fominykh, VG | 1 |
| Steinberg, SM | 1 |
| Galen, MA | 1 |
| Lazarus, JM | 1 |
| Lowrie, EG | 1 |
| Hampers, CL | 1 |
| Jaffe, N | 1 |
| Kaiser, BA | 1 |
| Mochon, M | 1 |
| de Chadarévian, JP | 1 |
| Ries, F | 1 |
| Sculier, JP | 1 |
| Bron, D | 1 |
| Page, RL | 1 |
| Leifer, CE | 1 |
| Matus, RE | 1 |
| Boccia, RV | 1 |
| Longo, DL | 1 |
| Lieber, ML | 1 |
| Jaffe, ES | 1 |
| Fisher, RI | 1 |
| Madero López, L | 1 |
| Muñoz Villa, A | 1 |
| Gallego Cobos, N | 1 |
| Onsurbe Ramírez, I | 1 |
| Durand, M | 1 |
| Hoerni-Simon, G | 1 |
| Hoerni, B | 1 |
| Armata, J | 1 |
| Marmont, AM | 1 |
| Damasio, EE | 1 |
| Oettgen, HF | 1 |
| Old, LJ | 1 |
| Boyse, EA | 1 |
| Campbell, HA | 1 |
| Philips, FS | 1 |
| Clarkson, BD | 1 |
| Tallal, L | 1 |
| Leeper, RD | 1 |
| Schwartz, MK | 1 |
| Kim, JH | 1 |
| Passwell, J | 1 |
| Boichis, H | 1 |
| Cohen, BE | 1 |
| Band, PR | 1 |
| Silverberg, DS | 1 |
| Henderson, JF | 1 |
| Ulan, RA | 1 |
| Wensel, RH | 1 |
| Banerjee, TK | 1 |
| Little, AS | 1 |
| Wyngaarden, JB | 1 |
| O'Duffy, JD | 1 |
| Scherbel, AL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00187005] | Phase 3 | 53 participants (Actual) | Interventional | 1998-07-31 | Terminated (stopped due to Toxicity) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for uric acid and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Acute tumor lysis syndrome in patients with high-grade non-Hodgkin's lymphoma.
Topics: Acute Disease; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Blood Urea Nitrogen; Bur | 1993 |
[Danger of hyperuricemia in the treatment of acute leukemia, lymphosarcoma and reticulosarcoma].
Topics: Acute Disease; Allopurinol; Antineoplastic Agents; Child; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1974 |
9 trials available for uric acid and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
A phase II study to evaluate the efficacy of low-dose rasburicase (1.5mg) in adolescent and adult acute leukemia and high-grade lymphomas with tumor lysis syndrome.
Topics: Adolescent; Adult; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Tumor Lysis Syndrome; Ur | 2023 |
Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin's Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study.
Topics: Child; Child, Preschool; China; Female; Humans; Hyperuricemia; Leukemia; Lymphoma, Non-Hodgkin; Male | 2023 |
In vitro and in vivo study on the antioxidant activity of dexrazoxane.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bleomycin; Chromans; Cyclophosphamide; | 2010 |
Efficacy and safety of rasburicase (recombinant urate oxidase) for the prevention and treatment of hyperuricemia during induction chemotherapy of aggressive non-Hodgkin's lymphoma: results of the GRAAL1 (Groupe d'Etude des Lymphomes de l'Adulte Trial on R
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Creatinine; Female; Humans; Hyperuricemia; In | 2003 |
Recombinant urate oxidase (rasburicase) for the prevention and treatment of tumor lysis syndrome in patients with hematologic malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calcium; Child; Child, Preschool; Female; Hematologic Ne | 2006 |
Prevention and treatment of hyperuricemia with rasburicase in children with leukemia and non-Hodgkin's lymphoma.
Topics: Adolescent; Allopurinol; Child; Child, Preschool; Female; Humans; Hyperuricemia; Infant; Leukemia; L | 2007 |
Urate oxidase in prevention and treatment of hyperuricemia associated with lymphoid malignancies.
Topics: Allopurinol; Antimetabolites; Antineoplastic Agents; Child; Child, Preschool; Female; Humans; Lympho | 1997 |
Recombinant urate oxidase for the prophylaxis or treatment of hyperuricemia in patients With leukemia or lymphoma.
Topics: Adolescent; Burkitt Lymphoma; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Hum | 2001 |
[Letter: Hyperphosphatemia and hypocalcemia following treatment of reticulosarcoma].
Topics: Aged; Anuria; Calcium; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Hypocalcemia; Lym | 1974 |
29 other studies available for uric acid and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Incidence and Risk Factors for Acute Kidney Injury After Chimeric Antigen Receptor T-Cell Therapy.
Topics: Acute Kidney Injury; Antigens, CD19; Cell- and Tissue-Based Therapy; Contrast Media; Creatine Kinase | 2022 |
Sample preparation in patients receiving uric acid oxidase (rasburicase) therapy.
Topics: Adult; Blood Specimen Collection; Humans; Lymphoma, Non-Hodgkin; Male; Recombinant Proteins; Urate O | 2003 |
Fatal uremia due to uric acid crystals in a case of lymphosarcoma.
Topics: Humans; Lymphoma; Lymphoma, Non-Hodgkin; Radiation Injuries; Radiotherapy; Uremia; Uric Acid | 1958 |
Dangers of uric-acid excretion during treatment of leukaemia and lymphosarcoma.
Topics: Humans; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Uric Acid | 1959 |
Hyperuricemia with uric acid nephropathy following nitrogen mustard therapy of lymphosarcoma; report of a case.
Topics: Hyperuricemia; Lymphoma; Lymphoma, Non-Hodgkin; Mechlorethamine; Nitrogen Mustard Compounds; Uric Ac | 1959 |
ANURIA DUE TO URIC ACID CRYSTALLURIA: AN UNUSUAL COMPLICATION OF THERAPY IN THE RETICULOSES.
Topics: Abdominal Neoplasms; Anuria; Blood; Genetic Diseases, X-Linked; Humans; Kidney Diseases; Leukemia, H | 1964 |
METABOLIC RELATIONSHIPS BETWEEN TUMOR AND HOST DURING MASSIVE DOSES OF PREDNISONE IN HUMAN NEOPLASTIC DISEASE.
Topics: 17-Ketosteroids; Adenocarcinoma; Biomedical Research; Blood; Calcium; Chlorides; Creatine; Creatinin | 1964 |
ACUTE RENAL FAILURE COMPLICATING LYMPHOSARCOMA.
Topics: Acute Kidney Injury; Blood; Humans; Kidney; Kidneys, Artificial; Lymphoma; Lymphoma, Non-Hodgkin; Ne | 1965 |
PREVENTION OF HYPERURICEMIA IN LEUKEMIA AND LYMPHOMA: USE OF ALOPURINOL, A XANTHINE OXIDASE INHIBITOR.
Topics: Adolescent; Antineoplastic Agents; Blood; Blood Urea Nitrogen; Drug Therapy; Geriatrics; Humans; Hyp | 1965 |
Renal and metabolic complications of undifferentiated and lymphoblastic lymphomas.
Topics: Adolescent; Adult; Burkitt Lymphoma; Calcium; Child; Child, Preschool; Female; Humans; Infant; Lymph | 1981 |
L3 acute lymphoblastic leukemia. Comparison with small noncleaved cell lymphoma involving the bone marrow.
Topics: Adolescent; Adult; Aged; Bone Marrow; Burkitt Lymphoma; Child; Female; Humans; Immunoglobulin M; Imm | 1994 |
Alkalinization and the tumor lysis syndrome.
Topics: Adolescent; Bicarbonates; Fluid Therapy; Furosemide; Humans; Hypocalcemia; Lymphoma, Non-Hodgkin; Ma | 1998 |
Efficacy of urate oxidase (uricozyme) in tumour lysis induced urate nephropathy.
Topics: Aged; Allantoin; Antimetabolites, Antineoplastic; Diuresis; Drug Evaluation; Female; Humans; Kidney | 1998 |
[Detection of soluble interleukin-2 receptor in the serum of patients with non-Hodgkin's lymphoma].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; beta 2-Microglobulin; Biomarkers, Tumor; C-Reactive Prot | 1998 |
[Hyperuricemic acute renal failure following radiotherapy in a case of lymphosarcoma (author's transl)].
Topics: Abdominal Neoplasms; Acute Kidney Injury; Adult; Female; Humans; Lymphoma, Non-Hodgkin; Radioisotope | 1979 |
[Uric nephropathy in malignant hemopaties: three cases with conserved diuresis (author's transl)].
Topics: Acute Kidney Injury; Allopurinol; Child; Child, Preschool; Diuresis; Female; Humans; Leukemia, Lymph | 1976 |
[Use of milurit in hyperuricemia in patients with malignant hemopathies].
Topics: Adolescent; Adult; Aged; Allopurinol; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma; | 1975 |
Hemodialysis for acute anuric uric acid nephropathy.
Topics: Abdominal Neoplasms; Acute Kidney Injury; Allopurinol; Child; Cyclophosphamide; Humans; Lymphoma, No | 1975 |
Eleven-year-old girl with acute renal failure, arthritis, hyperuricemia, and family history of rheumatic disorders.
Topics: Acute Kidney Injury; Arthritis, Gouty; Child; Female; Humans; Kidney; Kidney Neoplasms; Lymphoma, No | 1992 |
Spontaneous hyperuricemic acute renal failure.
Topics: Acute Kidney Injury; Aged; Axilla; Burkitt Lymphoma; Female; Humans; Lymphoma, Non-Hodgkin; Mandibul | 1987 |
Uric acid and phosphorus excretion in dogs with lymphosarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dog Diseases; Dogs; Female; L | 1986 |
Multiple recurrences of acute tumor lysis syndrome in an indolent non-Hodgkin's lymphoma.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blood Urea Nitrogen; Female; Humans; | 1985 |
[Metabolic and renal changes in lymphoproliferative syndromes of childhood].
Topics: Acute Kidney Injury; Antineoplastic Agents; Child; Cyclophosphamide; Female; Humans; Hypercalcemia; | 1985 |
Some clinical observations on the treatment with L-asparaginase of the acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Blood Chemical Analysis; Blood Platelets; Body | 1970 |
Inhibition of leukemias in man by L-asparaginase.
Topics: Adolescent; Adult; Asparaginase; Blood Platelets; Body Temperature; Bone Marrow Examination; Child; | 1967 |
Hyperuricemic nephropathy. Report of a case of lymphoblastic lymphosarcoma.
Topics: Acetazolamide; Acute Kidney Injury; Allopurinol; Bicarbonates; Biopsy; Child; Humans; Leukemia, Lymp | 1970 |
Xanthine nephropathy in a patient with lymphosarcoma treated with allopurinol.
Topics: Adult; Allopurinol; Autopsy; Cyclophosphamide; Humans; Kidney Calculi; Kidney Pelvis; Lymphoma, Non- | 1970 |
Allopurinol and xanthine nephropathy.
Topics: Adult; Allopurinol; Child; Humans; Kidney Calculi; Lymphoma, Non-Hodgkin; Male; Uric Acid; Xanthine | 1970 |
Treatment of gout and urate calculi with allopurinol.
Topics: Allopurinol; Colchicine; Follow-Up Studies; Gout; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; | 1968 |