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uric acid and Lung Injury, Ventilator-Induced

uric acid has been researched along with Lung Injury, Ventilator-Induced in 4 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Uric acid levels in lung lavage fluid of patients with acute lung injury (ALI) were determined."3.78Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury. ( Aslami, H; Hegeman, MA; Jongsma, G; Juffermans, NP; Kuipers, MT; Roelofs, JJ; Schultz, MJ; Tuip-de Boer, AM; van der Poll, T; Vlaar, AP; Wieland, CW, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, J1
Yan, Z1
Schwartz, DE1
Yu, J1
Malik, AB1
Hu, G1
Whidden, MA1
McClung, JM1
Falk, DJ1
Hudson, MB1
Smuder, AJ1
Nelson, WB1
Powers, SK1
Kuipers, MT2
Aslami, H2
Janczy, JR1
van der Sluijs, KF1
Vlaar, AP2
Wolthuis, EK1
Choi, G1
Roelofs, JJ2
Flavell, RA1
Sutterwala, FS1
Bresser, P1
Leemans, JC1
van der Poll, T2
Schultz, MJ2
Wieland, CW2
Juffermans, NP1
Tuip-de Boer, AM1
Hegeman, MA1
Jongsma, G1

Other Studies

4 other studies available for uric acid and Lung Injury, Ventilator-Induced

ArticleYear
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Apr-01, Volume: 190, Issue:7

    Topics: Animals; Carrier Proteins; Caspase 1; Disease Models, Animal; Inflammasomes; Interleukin-18; Interle

2013
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:2

    Topics: Animals; Diaphragm; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Hypoxan

2009
Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.
    Anesthesiology, 2012, Volume: 116, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Carrier Proteins; Caspase 1; Cytokines; Enzyme Activation; Ep

2012
Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Acute Lung Injury; Adult; Allopurinol; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability

2012