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uric acid and Leukomalacia, Periventricular

uric acid has been researched along with Leukomalacia, Periventricular in 2 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Leukomalacia, Periventricular: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

Research Excerpts

ExcerptRelevanceReference
"The purine metabolite hypoxanthine accumulates with hypoxia ischemia and with reperfusion is converted to uric acid (UA)."3.70Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant. ( Perlman, JM; Risser, R, 1998)
"Uric acid levels were related to serum creatinine (p < 0."1.32Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants. ( Rozycki, HJ; Sysyn, GD, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sysyn, GD1
Rozycki, HJ1
Perlman, JM1
Risser, R1

Other Studies

2 other studies available for uric acid and Leukomalacia, Periventricular

ArticleYear
Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants.
    Biology of the neonate, 2003, Volume: 83, Issue:4

    Topics: Apgar Score; Brain Diseases; Cerebral Hemorrhage; Creatinine; Gestational Age; Humans; Infant, Low B

2003
Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant.
    The Journal of pediatrics, 1998, Volume: 132, Issue:3 Pt 1

    Topics: Birth Weight; Brain Ischemia; Cerebral Hemorrhage; Gestational Age; Humans; Hypoxia; Infant, Newborn

1998