uric acid has been researched along with Left Ventricular Dysfunction in 43 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The level of serum uric acid (SUA) has been reported to be associated with left ventricular hypertrophy (LVH) and left ventricular diastolic dysfunction (LVDD)." | 8.02 | Association between serum uric acid and left ventricular hypertrophy/left ventricular diastolic dysfunction in patients with chronic kidney disease. ( Kim, HJ; Kim, IY; Kim, MJ; Kim, SR; Lee, DW; Lee, SB; Rhee, H; Seong, EY; Song, SH; Ye, BM, 2021) |
| " Recent epidemiological and clinical evidences suggest that serum uric acid can be one of the useful markers in assessing the risk of mortality in acute myocardial infarction." | 7.96 | A Study of the Serum Uric Acid Level as Prognostic Indicator in Acute Myocardial Infarction. ( Kumar, H; Kumar, N; Kumar, V; Nayyer, PS, 2020) |
| "Although serum uric acid (SUA) level is correlated with oxidative stress and serves as a marker of poor prognosis in heart failure patients, its possible association with subclinical left ventricular (LV) dysfunction has not been evaluated." | 7.96 | Serum uric acid level and subclinical left ventricular dysfunction: a community-based cohort study. ( Daimon, M; Di Tullio, MR; Hirokawa, M; Homma, S; Ishiwata, J; Kaneko, H; Komuro, I; Mizuno, Y; Morita, H; Nakanishi, K; Nakao, T; Sawada, N; Yoshida, Y, 2020) |
| " This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxostat) prescription on left ventricular hypertrophy (LVH), left ventricular (LV) diastolic function, and new-onset heart failure with preserved ejection fraction (HFpEF) in these patients." | 7.96 | Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia. ( Gu, J; Lin, H; Pan, JA; Wang, CQ; Zhang, JF, 2020) |
| "Hyperhomocysteinemia (HHcy) is recognized as a risk factor for cardiovascular disease." | 7.83 | High Prevalence of Hyperhomocysteinemia and Its Association with Target Organ Damage in Chinese Patients with Chronic Kidney Disease. ( Li, Y; Lou, T; Ma, X; Peng, H; Wang, C; Ye, Z; Zhang, J; Zhang, Q, 2016) |
| "We investigated the clinical profiles associated with serum uric acid (sUA) levels in a large cohort of patients hospitalized for worsening chronic heart failure with ejection fraction (EF) ≤40%, with specific focus on gender, race, and renal function based interactions." | 7.80 | Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial). ( Ambrosy, AP; Butler, J; Chioncel, O; Gheorghiade, M; Givertz, MM; Greene, SJ; Konstam, MA; Maggioni, AP; Mentz, RJ; Senni, M; Subacius, HP; Swedberg, K; Vaduganathan, M; Zannad, F, 2014) |
| " Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction." | 7.77 | Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011) |
| " The purpose of this study was to assess the relationship between levels of serum uric acid, activity of the renin-angiotensin-aldosterone system and TNF-alpha in heart failure patients with respect to the extent of left ventricular dysfunction." | 7.71 | Uric acid--a marker for systemic inflammatory response in patients with congestive heart failure? ( Gonsorcík, J; Kisel'ová, J; Olejníková, M; Olexa, P; Olexová, M; Tkác, I, 2002) |
| "Uric Acid (UA) has been related to the development of Cardio-Vascular (CV) events in patients affected by Chronic Coronary Syndromes (CCS)." | 5.62 | Uric acid in chronic coronary syndromes: Relationship with coronary artery disease severity and left ventricular diastolic parameter. ( Bossi, I; De Chiara, B; Giannattasio, C; Maloberti, A; Moreo, A; Nava, S; Oliva, F; Oreglia, J; Piccalò, G; Piccaluga, E; Pirola, R; Racioppi, A; Rebora, P; Soriano, F; Tassistro, E; Vallerio, P; Valsecchi, MG, 2021) |
| "Blood uric acid (UA) levels are frequently elevated in patients with heart failure and reduced ejection fraction (HFrEF), may lead to gout and are associated with worse outcomes." | 5.51 | Dapagliflozin reduces uric acid concentration, an independent predictor of adverse outcomes in DAPA-HF. ( de Boer, RA; Docherty, KF; Hammarstedt, A; Inzucchi, SE; Jhund, PS; Kosiborod, MN; Køber, L; Langkilde, AM; Lindholm, D; Martinez, FA; McDowell, K; McMurray, JJV; Morrow, DA; O'Meara, E; Ponikowski, P; Sabatine, MS; Sattar, N; Sjöstrand, M; Solomon, SD; Welsh, P, 2022) |
| "In conclusion, even in a short period of only 3 months, the administration of ARNI improved insulin resistance and consequently reduced the serum uric acid levels in patients with stable chronic heart failure." | 4.31 | Effects of angiotensin receptor-neprilysin inhibitor on insulin resistance in patients with heart failure. ( Inoue, Y; Kashiwagi, Y; Kawai, M; Kimura, H; Nagoshi, T; Ogawa, K; Oi, Y; Tanaka, Y; Yoshimura, M, 2023) |
| "The level of serum uric acid (SUA) has been reported to be associated with left ventricular hypertrophy (LVH) and left ventricular diastolic dysfunction (LVDD)." | 4.02 | Association between serum uric acid and left ventricular hypertrophy/left ventricular diastolic dysfunction in patients with chronic kidney disease. ( Kim, HJ; Kim, IY; Kim, MJ; Kim, SR; Lee, DW; Lee, SB; Rhee, H; Seong, EY; Song, SH; Ye, BM, 2021) |
| " Recent epidemiological and clinical evidences suggest that serum uric acid can be one of the useful markers in assessing the risk of mortality in acute myocardial infarction." | 3.96 | A Study of the Serum Uric Acid Level as Prognostic Indicator in Acute Myocardial Infarction. ( Kumar, H; Kumar, N; Kumar, V; Nayyer, PS, 2020) |
| "Although serum uric acid (SUA) level is correlated with oxidative stress and serves as a marker of poor prognosis in heart failure patients, its possible association with subclinical left ventricular (LV) dysfunction has not been evaluated." | 3.96 | Serum uric acid level and subclinical left ventricular dysfunction: a community-based cohort study. ( Daimon, M; Di Tullio, MR; Hirokawa, M; Homma, S; Ishiwata, J; Kaneko, H; Komuro, I; Mizuno, Y; Morita, H; Nakanishi, K; Nakao, T; Sawada, N; Yoshida, Y, 2020) |
| " This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxostat) prescription on left ventricular hypertrophy (LVH), left ventricular (LV) diastolic function, and new-onset heart failure with preserved ejection fraction (HFpEF) in these patients." | 3.96 | Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia. ( Gu, J; Lin, H; Pan, JA; Wang, CQ; Zhang, JF, 2020) |
| "To evaluate the effect of hyperuricemia (HU) on subclinical changes of left ventricle (LV) function and structure in patients with hypertension (HT) using three-dimensional speckle-tracking echocardiography (3DSTE) and to explore the relationships between serum uric acid (SUA) levels and three-dimensional speckle tracking echocardiography (3DSTE) parameters in hypertensive and nonhypertensive patients with HU." | 3.85 | Assessment of subclinical left ventricular changes in essential hypertensive patients with hyperuricemia: A three-dimensional speckle-tracking echocardiography study. ( Chen, Y; Fang, X; Jiang, L; Pan, C; Shu, X; Sun, M; Wang, X; Zhang, Z, 2017) |
| "Hyperhomocysteinemia (HHcy) is recognized as a risk factor for cardiovascular disease." | 3.83 | High Prevalence of Hyperhomocysteinemia and Its Association with Target Organ Damage in Chinese Patients with Chronic Kidney Disease. ( Li, Y; Lou, T; Ma, X; Peng, H; Wang, C; Ye, Z; Zhang, J; Zhang, Q, 2016) |
| "Serum uric acid levels were not significantly different in the asymptomatic hyperuricaemia, gouty arthritis without tophi and gouty tophi groups." | 3.80 | The effects of gout on left atrial volume remodelling: a prospective echocardiographic study. ( Chang, PJ; Chang, ST; Chen, MC; Chung, CM; Hsiao, JF; Lin, CL; Lin, JC; Pan, KL, 2014) |
| "Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF)." | 3.80 | Uricaemia and ejection fraction in elderly heart failure outpatients. ( Borghi, C; Cicero, AF; Cosentino, ER; Rinaldi, ER, 2014) |
| "We investigated the clinical profiles associated with serum uric acid (sUA) levels in a large cohort of patients hospitalized for worsening chronic heart failure with ejection fraction (EF) ≤40%, with specific focus on gender, race, and renal function based interactions." | 3.80 | Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial). ( Ambrosy, AP; Butler, J; Chioncel, O; Gheorghiade, M; Givertz, MM; Greene, SJ; Konstam, MA; Maggioni, AP; Mentz, RJ; Senni, M; Subacius, HP; Swedberg, K; Vaduganathan, M; Zannad, F, 2014) |
| " Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction." | 3.77 | Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011) |
| "This short-term prospective study included 40 patients with acute myocardial infarction (AMI) in whom we determined GGT activity, lipids, uric acid, homocysteine (Hcy), high sensitivity C-reactive protein (hsCRP) and left ventricular (LV) function on admission and on day 5 following AMI." | 3.77 | Is γ-glutamyl transferase activity a potential marker of left ventricular function during early postmyocardial infarction period? ( Dzubur, A; Hadzovic-Dzuvo, A; Jadric, R; Kiseljakovic, E; Lepara, O; Nakas-Icindic, E; Valjevac, A, 2011) |
| "Uric acid (UA) may be involved in chronic heart failure (HF) pathogenesis, entailing a worse outcome." | 3.74 | Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patients. ( Antolinos, MJ; Hurtado-Martínez, JA; Pascual-Figal, DA; Redondo, B; Ruiperez, JA; Valdes, M, 2007) |
| " The purpose of this study was to assess the relationship between levels of serum uric acid, activity of the renin-angiotensin-aldosterone system and TNF-alpha in heart failure patients with respect to the extent of left ventricular dysfunction." | 3.71 | Uric acid--a marker for systemic inflammatory response in patients with congestive heart failure? ( Gonsorcík, J; Kisel'ová, J; Olejníková, M; Olexa, P; Olexová, M; Tkác, I, 2002) |
| "To assess whether serum uric acid, which is a marker of impaired oxidative metabolism, might correlate with left ventricular systolic and diastolic dysfunction in patients with chronic heart failure (CHF)." | 3.71 | Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy. ( Brighetti, G; Cicoira, M; Franceschini, L; Golia, G; Rossi, A; Zanolla, L; Zardini, P; Zeni, P, 2002) |
| "We studied 62 patients with untreated hypertension, randomly assigned to cilnidipine or amlodipine for 48 weeks." | 2.82 | Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients. ( Eguchi, A; Fujiwara, S; Hirotani, S; Komamura, K; Koshiba, M; Mano, T; Masaki, M; Masuyama, T; Sugahara, M; Tsujino, T, 2016) |
| "Patients with type 2 diabetes mellitus (T2DM) are susceptible to coexisted with chronic kidney disease (CKD), which may increase cardiovascular mortality in these patients." | 1.62 | The additive effects of kidney dysfunction on left ventricular function and strain in type 2 diabetes mellitus patients verified by cardiac magnetic resonance imaging. ( Jiang, L; Li, Y; Ren, Y; Wang, J; Yan, WF; Yang, ZG; Zhang, Y, 2021) |
| "Uric Acid (UA) has been related to the development of Cardio-Vascular (CV) events in patients affected by Chronic Coronary Syndromes (CCS)." | 1.62 | Uric acid in chronic coronary syndromes: Relationship with coronary artery disease severity and left ventricular diastolic parameter. ( Bossi, I; De Chiara, B; Giannattasio, C; Maloberti, A; Moreo, A; Nava, S; Oliva, F; Oreglia, J; Piccalò, G; Piccaluga, E; Pirola, R; Racioppi, A; Rebora, P; Soriano, F; Tassistro, E; Vallerio, P; Valsecchi, MG, 2021) |
| "Gout is a common metabolic disorder characterized by hyperuricemia and chronic inflammation." | 1.42 | Gout, not hyperuricemia alone, impairs left ventricular diastolic function. ( Chang, PJ; Chang, ST; Chen, MC; Chung, CM; Lin, CL; Lin, JC; Pan, KL, 2015) |
| "We hypothesized that children with dilated cardiomyopathy who require hospital admission are at increased risk for death or transplantation during their first hospitalization and in the first year that follows." | 1.38 | Outcomes of children following a first hospitalization for dilated cardiomyopathy. ( Bernstein, D; Dao, D; Hollander, SA; Rosenthal, D; Sun, HY; Yeh, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 7 (16.28) | 29.6817 |
| 2010's | 18 (41.86) | 24.3611 |
| 2020's | 17 (39.53) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, Y | 1 |
| Yang, Z | 1 |
| Wang, T | 1 |
| Chen, X | 1 |
| Zhang, Q | 2 |
| Xie, Q | 1 |
| Wang, M | 1 |
| McDowell, K | 2 |
| Welsh, P | 1 |
| Docherty, KF | 1 |
| Morrow, DA | 1 |
| Jhund, PS | 2 |
| de Boer, RA | 1 |
| O'Meara, E | 1 |
| Inzucchi, SE | 1 |
| Køber, L | 1 |
| Kosiborod, MN | 1 |
| Martinez, FA | 1 |
| Ponikowski, P | 1 |
| Hammarstedt, A | 1 |
| Langkilde, AM | 1 |
| Sjöstrand, M | 1 |
| Lindholm, D | 1 |
| Solomon, SD | 1 |
| Sattar, N | 1 |
| Sabatine, MS | 1 |
| McMurray, JJV | 1 |
| Doehner, W | 2 |
| Packer, M | 1 |
| McMurray, JJ | 1 |
| Yang, CD | 1 |
| Feng, S | 1 |
| Chen, JW | 1 |
| Aihemaiti, M | 1 |
| Shu, XY | 1 |
| Quan, JW | 1 |
| Ding, FH | 1 |
| Lu, L | 1 |
| Shen, WF | 1 |
| Zhang, RY | 1 |
| Wang, XQ | 1 |
| Kashiwagi, Y | 1 |
| Nagoshi, T | 3 |
| Kimura, H | 2 |
| Tanaka, Y | 2 |
| Oi, Y | 1 |
| Inoue, Y | 3 |
| Ogawa, K | 3 |
| Kawai, M | 3 |
| Yoshimura, M | 3 |
| Kumar, N | 1 |
| Kumar, H | 1 |
| Kumar, V | 1 |
| Nayyer, PS | 1 |
| Nakanishi, K | 1 |
| Daimon, M | 1 |
| Yoshida, Y | 1 |
| Ishiwata, J | 1 |
| Sawada, N | 1 |
| Hirokawa, M | 1 |
| Kaneko, H | 1 |
| Nakao, T | 1 |
| Mizuno, Y | 1 |
| Morita, H | 1 |
| Di Tullio, MR | 1 |
| Homma, S | 1 |
| Komuro, I | 1 |
| Kanbay, M | 2 |
| Girerd, N | 2 |
| Machu, JL | 1 |
| Bozec, E | 1 |
| Duarte, K | 1 |
| Boivin, JM | 1 |
| Wagner, S | 1 |
| Ferreira, JP | 1 |
| Zannad, F | 3 |
| Rossignol, P | 2 |
| Pan, JA | 1 |
| Lin, H | 1 |
| Wang, CQ | 1 |
| Zhang, JF | 1 |
| Gu, J | 1 |
| Sung, KT | 1 |
| Lo, CI | 1 |
| Lai, YH | 1 |
| Tsai, JP | 1 |
| Yun, CH | 1 |
| Hsiao, CC | 1 |
| Kuo, JY | 1 |
| Hou, CJ | 1 |
| Hung, TC | 1 |
| Su, CH | 1 |
| Hung, CL | 1 |
| Yeh, HI | 1 |
| Cauwenberghs, N | 1 |
| Sabovčik, F | 1 |
| Vandenabeele, E | 1 |
| Kobayashi, Y | 1 |
| Haddad, F | 1 |
| Budts, W | 1 |
| Kuznetsova, T | 1 |
| Zhang, Y | 1 |
| Wang, J | 1 |
| Ren, Y | 1 |
| Yan, WF | 1 |
| Jiang, L | 2 |
| Li, Y | 2 |
| Yang, ZG | 1 |
| Maloberti, A | 1 |
| Bossi, I | 1 |
| Tassistro, E | 1 |
| Rebora, P | 1 |
| Racioppi, A | 1 |
| Nava, S | 1 |
| Soriano, F | 1 |
| Piccaluga, E | 1 |
| Piccalò, G | 1 |
| Oreglia, J | 1 |
| Vallerio, P | 1 |
| Pirola, R | 1 |
| De Chiara, B | 1 |
| Oliva, F | 1 |
| Moreo, A | 1 |
| Valsecchi, MG | 1 |
| Giannattasio, C | 1 |
| Sanikidze, Q | 1 |
| Mamacashvili, I | 1 |
| Petriashvili, S | 1 |
| Kim, IY | 1 |
| Ye, BM | 1 |
| Kim, MJ | 1 |
| Kim, SR | 1 |
| Lee, DW | 1 |
| Kim, HJ | 1 |
| Rhee, H | 1 |
| Song, SH | 1 |
| Seong, EY | 1 |
| Lee, SB | 1 |
| Liu, JH | 1 |
| Wu, MZ | 1 |
| Li, SM | 1 |
| Chen, Y | 2 |
| Ren, QW | 1 |
| Lin, QS | 1 |
| Ng, MY | 1 |
| Tse, HF | 1 |
| Yiu, KH | 1 |
| Uno, G | 1 |
| Ito, S | 1 |
| Yoshii, A | 1 |
| Tanaka, TD | 1 |
| Minai, K | 2 |
| Ogawa, T | 2 |
| Georgiopoulos, G | 1 |
| Tsioufis, C | 1 |
| Kalos, T | 1 |
| Magkas, N | 1 |
| Roussos, D | 1 |
| Chrysohoou, C | 1 |
| Sarri, G | 1 |
| Syrmali, K | 1 |
| Georgakopoulos, P | 1 |
| Tousoulis, D | 1 |
| Owczarek, AJ | 1 |
| Choręza, P | 1 |
| Arabzada, H | 1 |
| Chudek, J | 1 |
| Wojnicz, R | 1 |
| Oki, Y | 1 |
| Morimoto, S | 1 |
| Tanaka, T | 2 |
| Pan, KL | 3 |
| Lin, JC | 3 |
| Lin, CL | 3 |
| Chen, MC | 3 |
| Chang, PJ | 2 |
| Hsiao, JF | 1 |
| Chang, ST | 3 |
| Chung, CM | 3 |
| Borghi, C | 1 |
| Cosentino, ER | 1 |
| Rinaldi, ER | 1 |
| Cicero, AF | 1 |
| Houssen, ME | 1 |
| El-Mahdy, RH | 1 |
| Shahin, DA | 1 |
| Hsu, JT | 1 |
| Vaduganathan, M | 1 |
| Greene, SJ | 1 |
| Ambrosy, AP | 1 |
| Mentz, RJ | 1 |
| Subacius, HP | 1 |
| Chioncel, O | 1 |
| Maggioni, AP | 1 |
| Swedberg, K | 1 |
| Konstam, MA | 1 |
| Senni, M | 1 |
| Givertz, MM | 1 |
| Butler, J | 1 |
| Gheorghiade, M | 1 |
| Jia, G | 1 |
| Habibi, J | 1 |
| Bostick, BP | 1 |
| Ma, L | 1 |
| DeMarco, VG | 1 |
| Aroor, AR | 1 |
| Hayden, MR | 1 |
| Whaley-Connell, AT | 1 |
| Sowers, JR | 1 |
| von Lueder, TG | 1 |
| Atar, D | 1 |
| Agewall, S | 1 |
| Lamiral, Z | 1 |
| Pitt, B | 1 |
| Dickstein, K | 1 |
| Masaki, M | 1 |
| Mano, T | 1 |
| Eguchi, A | 1 |
| Fujiwara, S | 1 |
| Sugahara, M | 1 |
| Hirotani, S | 1 |
| Tsujino, T | 1 |
| Komamura, K | 1 |
| Koshiba, M | 1 |
| Masuyama, T | 1 |
| Ye, Z | 1 |
| Wang, C | 1 |
| Zhang, J | 1 |
| Ma, X | 1 |
| Peng, H | 1 |
| Lou, T | 1 |
| Fang, X | 1 |
| Pan, C | 1 |
| Sun, M | 1 |
| Zhang, Z | 1 |
| Wang, X | 1 |
| Shu, X | 1 |
| Chen, CC | 1 |
| Hsu, YJ | 1 |
| Lee, TM | 1 |
| Valjevac, A | 1 |
| Dzubur, A | 1 |
| Nakas-Icindic, E | 1 |
| Hadzovic-Dzuvo, A | 1 |
| Lepara, O | 1 |
| Kiseljakovic, E | 1 |
| Jadric, R | 1 |
| Hollander, SA | 1 |
| Bernstein, D | 1 |
| Yeh, J | 1 |
| Dao, D | 1 |
| Sun, HY | 1 |
| Rosenthal, D | 1 |
| Olexa, P | 1 |
| Olexová, M | 1 |
| Gonsorcík, J | 1 |
| Tkác, I | 1 |
| Kisel'ová, J | 1 |
| Olejníková, M | 1 |
| Podbregar, M | 1 |
| Voga, G | 1 |
| Sakai, H | 1 |
| Tsutamoto, T | 1 |
| Tsutsui, T | 1 |
| Ishikawa, C | 1 |
| Horie, M | 1 |
| Pascual-Figal, DA | 1 |
| Hurtado-Martínez, JA | 1 |
| Redondo, B | 1 |
| Antolinos, MJ | 1 |
| Ruiperez, JA | 1 |
| Valdes, M | 1 |
| von Haehling, S | 1 |
| Anker, SD | 1 |
| Mazza, A | 1 |
| Zamboni, S | 1 |
| Tikhonoff, V | 1 |
| Scarpa, R | 1 |
| Cuppini, S | 1 |
| Zennaro, R | 1 |
| Pessina, AC | 1 |
| Casiglia, E | 1 |
| Hoeper, MM | 1 |
| Hohlfeld, JM | 1 |
| Fabel, H | 1 |
| Cicoira, M | 1 |
| Zanolla, L | 1 |
| Rossi, A | 1 |
| Golia, G | 1 |
| Franceschini, L | 1 |
| Brighetti, G | 1 |
| Zeni, P | 1 |
| Zardini, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-12-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for uric acid and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Dapagliflozin reduces uric acid concentration, an independent predictor of adverse outcomes in DAPA-HF.
Topics: Aged; Benzhydryl Compounds; Female; Glucosides; Heart Failure; Humans; Male; Middle Aged; Stroke Vol | 2022 |
Serum uric acid is associated with mortality and heart failure hospitalizations in patients with complicated myocardial infarction: findings from the High-Risk Myocardial Infarction Database Initiative.
Topics: Aged; Biomarkers; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Myocardial Infa | 2015 |
Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients.
Topics: Amlodipine; Atrial Function, Left; Atrial Remodeling; Biomarkers; Blood Pressure; Calcium Channel Bl | 2016 |
Effect of selective and nonselective beta-blockers on resting energy production rate and total body substrate utilization in chronic heart failure.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Aged; Basal Metabolism; Bisoprolol; Blood Pressure; Bod | 2002 |
39 other studies available for uric acid and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Impact of serum uric acid on left ventricular diastolic function in patients with autoimmune diseases.
Topics: Autoimmune Diseases; Diastole; Humans; Uric Acid; Ventricular Dysfunction, Left; Ventricular Functio | 2022 |
Sodium-glucose cotransporter 2 inhibitor treatment lowers serum uric acid in patients with heart failure with reduced ejection fraction - lessons from clinical trials. Letter regarding the article 'Dapagliflozin reduces uric acid concentration, an indepen
Topics: Diabetes Mellitus, Type 2; Glucose; Heart Failure; Humans; Sodium; Stroke Volume; Uric Acid; Ventric | 2022 |
Reply to 'Sodium-glucose cotransporter 2 inhibitor treatment lowers serum uric acid in patients with heart failure with reduced ejection fraction - lessons from clinical trials'.
Topics: Glucose; Heart Failure; Humans; Sodium; Stroke Volume; Uric Acid; Ventricular Dysfunction, Left | 2022 |
Serum Uric Acid Is Associated with the Progression of Left Ventricular Diastolic Dysfunction in Apparently Healthy Subjects.
Topics: Healthy Volunteers; Heart Failure; Humans; Stroke Volume; Uric Acid; Ventricular Dysfunction, Left | 2022 |
Effects of angiotensin receptor-neprilysin inhibitor on insulin resistance in patients with heart failure.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2023 |
A Study of the Serum Uric Acid Level as Prognostic Indicator in Acute Myocardial Infarction.
Topics: Humans; Middle Aged; Myocardial Infarction; Prognosis; Prospective Studies; Uric Acid; Ventricular D | 2020 |
Serum uric acid level and subclinical left ventricular dysfunction: a community-based cohort study.
Topics: Aged; Cohort Studies; Echocardiography; Female; Heart Failure; Humans; Male; Middle Aged; Uric Acid; | 2020 |
Impact of Uric Acid on Hypertension Occurrence and Target Organ Damage: Insights From the STANISLAS Cohort With a 20-Year Follow-up.
Topics: Adult; Aged; Albuminuria; Blood Pressure; Cohort Studies; Creatinine; Female; France; Glomerular Fil | 2020 |
Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia.
Topics: Aged; Asymptomatic Diseases; Biomarkers; Blood Pressure; Databases, Factual; Diastole; Disease Progr | 2020 |
Associations of serum uric acid level and gout with cardiac structure, function and sex differences from large scale asymptomatic Asians.
Topics: Adult; Asian People; Asymptomatic Diseases; Echocardiography, Doppler; Female; Gout; Heart Atria; He | 2020 |
Subclinical Heart Dysfunction in Relation to Metabolic and Inflammatory Markers: A Community-Based Study.
Topics: Asymptomatic Diseases; Atrial Function, Left; Belgium; Biomarkers; Blood Glucose; Echocardiography, | 2021 |
The additive effects of kidney dysfunction on left ventricular function and strain in type 2 diabetes mellitus patients verified by cardiac magnetic resonance imaging.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Disease Progression; Femal | 2021 |
Uric acid in chronic coronary syndromes: Relationship with coronary artery disease severity and left ventricular diastolic parameter.
Topics: Aged; Biomarkers; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Diastole; | 2021 |
PREVALENCE OF HYPERURICEMIA IN PATIENTS WITH CHRONIC HEART FAILURE.
Topics: Female; Heart Failure; Humans; Hyperuricemia; Prevalence; Uric Acid; Ventricular Dysfunction, Left; | 2021 |
Association between serum uric acid and left ventricular hypertrophy/left ventricular diastolic dysfunction in patients with chronic kidney disease.
Topics: Biomarkers; Cross-Sectional Studies; Echocardiography; Female; Humans; Hypertrophy, Left Ventricular | 2021 |
Association of serum uric acid with biventricular myocardial dysfunction in patients with type 2 diabetes mellitus.
Topics: Aged; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Echocardiography; Female; Hong | 2021 |
Close linkage between serum uric acid and cardiac dysfunction in patients with ischemic heart disease according to covariance structure analysis.
Topics: Aged; Cardiac Catheterization; Female; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial | 2017 |
Serum Uric Acid is Independently Associated with Diastolic Dysfunction in Apparently Healthy Subjects with Essential Hypertension.
Topics: Aged; Biomarkers; Diastole; Essential Hypertension; Female; Humans; Hyperuricemia; Male; Middle Aged | 2019 |
Kidney Function, Nutritional Status, and the Left Ventricle Dysfunction Are Associated with Serum Uric Acid Levels in Patients with Heart Failure with Reduced Ejection Fraction.
Topics: Adult; Female; Fuzzy Logic; Glomerular Filtration Rate; Heart Failure; Humans; Male; Middle Aged; Na | 2018 |
High Serum Uric Acid is Highly Associated with a Reduced Left Ventricular Ejection Fraction Rather than Increased Plasma B-type Natriuretic Peptide in Patients with Cardiovascular Diseases.
Topics: Aged; Aging; Biomarkers; Cardiac Catheterization; Cardiovascular Diseases; Female; Humans; Male; Mid | 2019 |
The effects of gout on left atrial volume remodelling: a prospective echocardiographic study.
Topics: Adult; Aged; Arthritis, Gouty; Atrial Remodeling; Cardiac Volume; Case-Control Studies; Cross-Sectio | 2014 |
Uricaemia and ejection fraction in elderly heart failure outpatients.
Topics: Aged; Female; Heart Failure; Humans; Hyperuricemia; Male; Outpatients; Prospective Studies; Stroke V | 2014 |
Serum soluble toll-like receptor 2: a novel biomarker for systemic lupus erythematosus disease activity and lupus-related cardiovascular dysfunction.
Topics: Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Biomarkers; Case-Control Studies; Creatinine; | 2016 |
Impact of gout on left atrial function: a prospective speckle-tracking echocardiographic study.
Topics: Adult; Aged; Atrial Function, Left; Echocardiography, Doppler; Female; Gout; Humans; Male; Middle Ag | 2014 |
Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial).
Topics: Age Factors; Aged; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Black or African America | 2014 |
Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet.
Topics: Allopurinol; Animals; Biomarkers; Diet, Western; Dietary Fats; Dietary Sucrose; Disease Models, Anim | 2015 |
Gout, not hyperuricemia alone, impairs left ventricular diastolic function.
Topics: Adult; Aged; Biomarkers; Cohort Studies; Diastole; Female; Gout; Humans; Hyperuricemia; Male; Middle | 2015 |
High Prevalence of Hyperhomocysteinemia and Its Association with Target Organ Damage in Chinese Patients with Chronic Kidney Disease.
Topics: Adult; Calcium Phosphates; Carotid Arteries; Carotid Intima-Media Thickness; Cross-Sectional Studies | 2016 |
Assessment of subclinical left ventricular changes in essential hypertensive patients with hyperuricemia: A three-dimensional speckle-tracking echocardiography study.
Topics: Aged; Echocardiography; Echocardiography, Three-Dimensional; Essential Hypertension; Female; Heart V | 2017 |
Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia.
Topics: Allopurinol; Analysis of Variance; Animals; Antioxidants; Atrasentan; Biomarkers; Cyclic N-Oxides; D | 2011 |
Is γ-glutamyl transferase activity a potential marker of left ventricular function during early postmyocardial infarction period?
Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Colorimetry; Creatine Kinase, MB Form; Dilatatio | 2011 |
Outcomes of children following a first hospitalization for dilated cardiomyopathy.
Topics: Adolescent; Age Factors; Atrial Function; Biomarkers; Cardiomyopathy, Dilated; Cardiotonic Agents; C | 2012 |
Uric acid--a marker for systemic inflammatory response in patients with congestive heart failure?
Topics: Aged; Aldosterone; Creatinine; Female; Heart Failure; Humans; Leukocyte Count; Male; Middle Aged; Pr | 2002 |
Serum level of uric acid, partly secreted from the failing heart, is a prognostic marker in patients with congestive heart failure.
Topics: Aged; Biomarkers; Case-Control Studies; Data Interpretation, Statistical; Female; Heart Failure; Hum | 2006 |
Hyperuricaemia and long-term outcome after hospital discharge in acute heart failure patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Female; Follow-Up Studies; | 2007 |
Uric acid as a prognostic marker in acute heart failure--new expectations from an old molecule.
Topics: Acute Disease; Biomarkers; Heart Failure; Humans; Hyperuricemia; Patient Discharge; Prognosis; Survi | 2007 |
Pulse hypertension: a new component of the metabolic syndrome in elderly women?
Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Blood Glucose; Blood Pressure; Coronary Disease; Cr | 2007 |
Hyperuricaemia in patients with right or left heart failure.
Topics: Adult; Aged; Arthritis, Gouty; Cardiomyopathy, Dilated; Diuretics; Female; Hemodynamics; Humans; Hyp | 1999 |
Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy.
Topics: Aged; Biomarkers; Diastole; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Mit | 2002 |