uric acid has been researched along with Kidney Diseases in 961 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the efficacy of febuxostat combined with hydration on contrast-induced nephropathy (CIN) in coronary heart disease patients with hyperuricemia undergoing percutaneous coronary intervention (PCI)." | 9.51 | Febuxostat combined with hydration for the prevention of contrast-induced nephropathy in hyperuricemia patients undergoing percutaneous coronary intervention: A CONSORT-compliant randomized controlled trial. ( He, Z; Li, M; Ma, G; Teng, W; Xia, Z; Zhai, X, 2022) |
| " However, there is no data about the effect of lowering uric acid level on renal functions and proteinuria in renal transplant recipients." | 9.51 | Effect of allopurinol drug use on GFR and proteinuria in patients with renal transplant recipients (ADOPTR study). ( Cingöz, M; Özdemir, O; Şahin, AZ; Usalan, C; Usalan, Ö, 2022) |
| "A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal and metabolic diseases has been reported in many basic and epidemiological studies." | 9.41 | Update in uric acid, hypertension, and cardiovascular diseases. ( Ae, R; Andres-Hernando, A; Borghi, C; Hisatome, I; Kanbay, M; Kodama, T; Kuwabara, M; Lanaspa, MA, 2023) |
| "The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality but also acute coronary syndrome, stroke and heart failure." | 9.41 | The Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation. ( Agabiti Rosei, E; Angeli, F; Barbagallo, CM; Bernardino, B; Bombelli, M; Borghi, C; Cappelli, F; Casiglia, E; Cianci, R; Ciccarelli, M; Cicero, AFG; Cirillo, M; Cirillo, P; D'Elia, L; Dell'Oro, R; Desideri, G; Facchetti, R; Ferri, C; Galletti, F; Gesualdo, L; Giannattasio, C; Grassi, G; Iaccarino, G; Lippa, L; Mallamaci, F; Maloberti, A; Masi, S; Masulli, M; Mazza, A; Mengozzi, A; Muiesan, ML; Nazzaro, P; Palatini, P; Parati, G; Pauletto, P; Pontremoli, R; Pugliese, NR; Quarti-Trevano, F; Rattazzi, M; Reboldi, G; Rivasi, G; Russo, E; Salvetti, M; Tikhonoff, V; Tocci, G; Ungar, A; Verdecchia, P; Viazzi, F; Virdis, A; Volpe, M, 2023) |
| "To determine the efficacy and safety of increasing the allopurinol dose above the proposed creatinine clearance-based dose in patients with gout." | 9.15 | Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment. ( Barclay, ML; Chapman, PT; Frampton, C; James, J; O'Donnell, JL; Stamp, LK; Zhang, M, 2011) |
| "The purpose of this study was to compare urate-lowering (UL) efficacy and safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA) > or = 8." | 9.14 | The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. ( Becker, MA; Espinoza, LR; Lademacher, C; Lloyd, E; MacDonald, P; Schumacher, HR; Wells, AF, 2010) |
| "Elevated serum uric acid concentration is a common laboratory finding in subjects with metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events." | 8.89 | Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal? ( Kapusta, DR; Rasheed, K; Reisin, E; Soltani, Z, 2013) |
| "Over the last decade, the biologic interference of uric acid with the cardiovascular (CV) system and the kidney has been intensively investigated, and several experimental studies in animal models and in vitro documented that hyperuricemia may trigger hypertension and incite endothelial dysfunction, vascular damage and renal disease." | 8.89 | Uric acid, hypertension, and cardiovascular and renal complications. ( Mallamaci, F; Zoccali, C, 2013) |
| "To evaluate the association of serum uric acid and the incidence and prognosis of kidney diseases systematically, so as to provide reference for the treatment and prevention of kidney diseases." | 8.87 | [The correlation between uric acid and the incidence and prognosis of kidney diseases: a systematic review and meta-analysis of cohort studies]. ( Huang, Y; Li, J; Li, YL; Wang, L; Yuan, WM, 2011) |
| "After uric acid was recognized as the causative factor in gout, increased prevalence of renal disease and hypertension in this patient population caught the attention of the medical community." | 8.86 | Uric acid in hypertension and renal disease: the chicken or the egg? ( Covic, A; Dogan, E; Kanbay, M; Lanaspa, MA; Solak, Y, 2010) |
| "This article critically evaluates the clinical evidence regarding the influence of uric acid on hypertension, cardiovascular disease, and kidney disease." | 8.82 | Clinical evidence for the influence of uric acid on hypertension, cardiovascular disease, and kidney disease: a statistical modeling perspective. ( Short, RA; Tuttle, KR, 2005) |
| "Although hyperuricemia has long been associated with renal disease, uric acid has not been considered as a true mediator of progression of renal disease." | 8.82 | Uric acid and chronic renal disease: possible implication of hyperuricemia on progression of renal disease. ( Kang, DH; Nakagawa, T, 2005) |
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 8.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| " Serum uric acid to albumin ratio (UAR) is a novel marker, which is associated with acute kidney injury in intensive care unit patients." | 8.31 | Serum Uric Acid to Albumin Ratio Can Predict Contrast-Induced Nephropathy in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention. ( Akbulut, T; Çınar, T; Şaylık, F; Selçuk, M, 2023) |
| "Correlation influence factor analysis of gout patients' serum uric acid (SUA) levels, their examination fees, and various complications were explored." | 8.31 | Association between serum uric acid levels of patients with gout and their complications and examination fees: A cross-sectional analysis. ( Dang, W; Liu, J; Wang, J; Xu, D; You, L; Zhao, L, 2023) |
| "Uric acid is the final product of purine metabolism, and excessive serum uric acid can cause gouty arthritis and uric acid nephropathy." | 8.02 | Bmk9 and Uricase Nanoparticle Complex for the Treatment of Gouty Arthritis and Uric Acid Nephropathy. ( An, M; Fu, H; Han, T; Li, W; Wang, M, 2021) |
| "The current work explored the influences of nifuroxazide, an in vivo inhibitor of signal transducer and activator of transcription-3 (STAT-3) activation, on tubulointerstitial fibrosis in rats with obstructive nephropathy using unilateral ureteral obstruction (UUO) model." | 8.02 | Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation. ( Hassan, NME; Said, E; Shehatou, GSG, 2021) |
| "To investigate the incidence and potential risk factors for development of fenofibrate-associated nephrotoxicity in gout patients." | 8.02 | Effects of fenofibrate therapy on renal function in primary gout patients. ( Chen, Y; Cheng, X; Cui, L; Han, L; He, Y; Ji, A; Ji, X; Li, C; Li, H; Li, X; Liu, Z; Lu, J; Ma, L; Merriman, TR; Ren, W; Sun, W; Wang, C; Wang, X; Yuan, X; Zhang, H, 2021) |
| " The effects of API on renal function, inflammation, fibrosis, and uric acid (UA) metabolism in mice with HN were evaluated." | 8.02 | Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway. ( Cao, Y; Chen, Y; Huang, Q; Jiang, Y; Li, L; Li, Y; Luo, J; Pang, J; Wu, T; Zhang, L; Zhao, Z; Zhou, P, 2021) |
| "Berberine (BBR) is an active component of Phellodendri Cortex (PC), which is a traditional Chinese medicine that has been prescribed clinically for hyperuricemia (HUA) for hundreds of years." | 8.02 | Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model. ( Chen, J; Huang, Z; Li, Q; Li, Y; Liu, D; Su, Z; Xie, J; Zeng, H; Zheng, J, 2021) |
| " The effects of phloretin on renal function, fibrosis, oxidative stress, inflammation, and UA metabolism in HUA mice were evaluated." | 7.96 | Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption. ( Chen, Y; Cheng, J; Cui, D; Li, L; Liu, J; Liu, S; Lu, Y; Mao, R; Tang, M; Wang, C; Yuan, Y; Zhao, M, 2020) |
| "Lesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI." | 7.91 | Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. ( Baumgartner, S; Goldfarb, DS; Jalal, D; Pillinger, M; Saag, KG; Schechter, BM; Terkeltaub, R; Valiyil, R; White, WB, 2019) |
| "The aim of this study was to assess the association between serum uric acid concentration (SUAC) and the parameters of the metabolic syndrome (MetS) and insulin resistance (IR)." | 7.91 | Associations Between Serum Uric Acid Concentrations and Cardiometabolic Risk and Renal Injury in Obese and Overweight Children ( Ersoy, B; Özalp Kızılay, D; Şen, S, 2019) |
| "Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension." | 7.88 | Sex-related relationships between uric acid and target organ damage in hypertension. ( Casati, M; Falbo, R; Giannattasio, C; Grassi, G; Maggioni, S; Maloberti, A; Nava, S; Occhi, L; Panzeri, F; Signorini, S; Triglione, N, 2018) |
| " Both Diosmin and Crocin improved insulin resistance, decreased blood pressure, uric acid, lipoproteins and blocked diabetic nephropathy as indicated by reduction of albumin excretion rate and albumin/creatinine ratio." | 7.88 | Diosmin and crocin alleviate nephropathy in metabolic syndrome rat model: Effect on oxidative stress and low grade inflammation. ( El Fayoumi, HM; El-Fawal, R; Mahmoud, MF, 2018) |
| "To explore the effects of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility (PR) on uric acid metabolism and the expression of urinary neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in rats with hyperuricemia." | 7.85 | Effect of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility on uric acid metabolism and urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in rats with hyperuricemia. ( Han, B; Hu, XG; Huang, HZ; Lei, M; Li, Z; Shi, W; Zhou, XM; Zhu, CX, 2017) |
| "The aim of this study was to evaluate relationships between serum uric acid (SUA) and newly emergent acute myocardial infarction (AMI), congestive heart failure (CHF), coronary artery disease (CAD), composite cardiovascular (CV) events (AMI, CHF, CAD), hypertension, hyperlipidemia, and renal disease in gout patients." | 7.85 | Evaluation of the Relationship Between Serum Uric Acid Levels and Cardiovascular Events in Patients With Gout: A Retrospective Analysis Using Electronic Medical Record Data. ( Bienen, EJ; Essex, MN; Hopps, M; Makinson, GT; Mardekian, J; Udall, M, 2017) |
| "Although aspirin-clopidogrel combination is more useful for acute coronary syndrome (ACS), the renal safety of this combination had not been established." | 7.83 | Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome. ( Baber, M; HamidAkash, MS; Hussain, SB; Irfan, M; Qadir, MI; Rehman, A, 2016) |
| "Longitudinal changes in uric acid levels were independently associated with the renal function decline in elderly patients with hypertension." | 7.83 | Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up. ( Chen, H; Huang, F; Lin, C; Lin, F; Zhang, H; Zhu, P, 2016) |
| "Hyponatremia associated with high urinary fractional excretion of uric acid which persists after serum sodium is corrected is the cardinal feature of salt losing nephropathy (SLN)." | 7.83 | Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury? ( Johnson, RJ; Lanaspa, MA; Lee, SK; Sánchez-Lozada, LG, 2016) |
| "While the prevalence of gout was calculated by counting patients with this diagnosis hyperuricemia was inferred in patients taking allopurinol at hospital admission or discharge, on the assumption that this drug was only prescribed owing to the finding of high serum levels of uric acid." | 7.80 | Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly. ( Conca, A; Corrao, S; Djade, CD; Franchi, C; Mannucci, PM; Marcucci, M; Marengoni, A; Nobili, A; Pasina, L; Salerno, F; Tettamanti, M, 2014) |
| "To examine the association between renal function, serum uric acid and markers of both pro-inflammatory and prothrombotic state in patients with diabetes mellitus (DM), metabolic syndrome and coronary artery disease." | 7.77 | Uric acid as a link between renal dysfunction and both pro-inflammatory and prothrombotic state in patients with metabolic syndrome and coronary artery disease. ( Buraczyńska, MJ; Kondracki, B; Rychta, E; Waciński, P; Wysokiński, A; Zapolski, T, 2011) |
| " We examined the association between uric acid levels and various clinical parameters, including the components of metabolic syndrome, in essential hypertension." | 7.76 | Association of uric acid with risk factors for chronic kidney disease and metabolic syndrome in patients with essential hypertension. ( Anzawa, R; Fujii, T; Seki, S; Tsutsui, K; Yamazaki, K; Yoshimura, M, 2010) |
| "To investigate if increased lipid peroxidation is involved in hypercholesterolemia-induced hypertension and renal injury, we examined the effects of allopurinol, a xanthine oxidase inhibitor, on these conditions." | 7.73 | Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats. ( Atarashi, K; Ishiyama, A; Minami, M; Omata, M; Takagi, M, 2005) |
| "We studied the serum phosphorus (P) level of 110 patients with multiple myeloma (MM) (age range 42-83 years, median 62 years) and evaluated the relationship between that and other prognostic factors." | 7.73 | Prognostic significance of the serum phosphorus level and its relationship with other prognostic factors in multiple myeloma. ( Arai, C; Fujimoto, Y; Izumi, H; Katoh, M; Kuraishi, Y; Nagase, D; Natori, K; Okuda, S; Sugasawa, Y; Umeda, M, 2006) |
| "To study effects of uric acid disbolism in combination with other metabolic disturbances on prevalence and clinical symptoms of arterial hypertension; contribution of uric acid nephropathy to its development." | 7.73 | [Relationships between arterial hypertension, metabolic disturbances and uric acid nephropathy]. ( Balkarov, IM; Britov, AN; Deev, AD; Eliseeva, NA, 2006) |
| "To analyse relationships between left ventricular myocardium mass (LVMM) and imbalance of uric acid metabolism in patients with arterial hypertension (AH)." | 7.71 | [Relationship between mass of the left ventricular myocardium and uric acid metabolic imbalance in patients with arterial hypertension]. ( Anikina, SA; Balkarov, IM; Donskov, AS; Feofanova, ID; Golub', GV; Prilepo, NA; Saltykova, NG; Sviderskaia, NS, 2001) |
| "The N-acetyl-beta-D-glucosaminidase (NAG) activities and albumin levels in the urine of 32 patients with active rheumatoid arthritis treated with low-dose pulse methotrexate (MTX) have been investigated." | 7.69 | N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment. ( Swierkot, J; Szechiński, J; Wiland, P, 1997) |
| "In patients with healthy native kidneys, long-term cyclosporine therapy, even at a low dose (5 mg/kg per day), is nephrotoxic and is associated with a high incidence of hypertension." | 7.68 | Renal function and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmune uveitis. ( Aupetit, B; Baumelou, A; Benhmida, M; Deray, G; Jacobs, C; Le Hoang, P; Maksud, P, 1992) |
| "Ten patients with gout, hypertension, and mild to moderate renal insufficiency were studied for possible lead nephropathy by measuring stimulated urinary lead excretion." | 7.67 | Occult lead intoxication in patients with gout and kidney disease. ( Cecere, FA; Saylor, RP; Wright, LF, 1984) |
| "Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males." | 7.67 | Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988) |
| "Chronic lead nephtropathy, secondary gout (lead-gout) and porphyrinuria may develop after long lasting professional exposure to lead." | 7.65 | [Chronic lead poisoning: Lead gout with giant tophi on the skin, nephrophathy and porphyrinopathy]. ( Künzig, M; Orfanos, CE, 1975) |
| "2%) showed macroscopic renal uric acid infarctions." | 7.65 | Uric acid infarctions in the kidneys of newborn infants. A study on the changing incidence and on oxypurine ratios. ( Dörner, K; Eigster, G; Grünitz, J; Harms, D; Manzke, H, 1977) |
| "Obstructive uric acid nephropathy, a potentially lethal complication of acute renal failure due to glomerulonephritis, is described and illustrated." | 7.65 | Acute lobular (membranoproliferative) glomerulonephritis with hyperuricemia and obstructive uric acid nephropathy. ( Allen, AC, 1976) |
| "Nine people from four families living in rural parts of Scotland have been found to suffer from clinical or biochemical effects of lead poisoning." | 7.65 | Lead poisoning in rural Scotland. ( Beattie, AD; Dagg, JH; Goldberg, A; Ronald, J; Wang, I, 1972) |
| "Uric acid is an end product of purine metabolism in human beings." | 6.66 | Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator. ( Adomako, E; Moe, OW, 2020) |
| "Hyperuricemia affects one out of five adults as a result of the Western diet, insulin resistance, and renal dysfunction." | 6.61 | Uric acid and hypertension: a focused review and practical recommendations. ( Borghi, C; Burnier, M; De Becker, B; van de Borne, P, 2019) |
| "Hyperuricemia is a prevalent finding in patients presenting metabolic syndrome, although its clinical meaning is still controversial and often underestimated." | 6.46 | Uric acid as a factor in the metabolic syndrome. ( Batista, MC; Borges, RL; Ribeiro, AB; Zanella, MT, 2010) |
| "Uric acid is an antioxidant and perhaps helps to control blood pressure during a low Na+ diet through stimulation of the renin-angiotensin system." | 6.44 | Uric acid: bystander or culprit in hypertension and progressive renal disease? ( Menè, P; Punzo, G, 2008) |
| "Purine inborn errors of metabolism (IEM) are serious hereditary disorders, which should be suspected in any case of neonatal fitting, failure to thrive, recurrent infections, neurological deficit, renal disease, self-mutilation and other manifestations." | 6.44 | Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions. ( Aquino Neto, FR; de Oliveira, ML; Gomes, LN; Oliveira, CP; Scalco, FB; Simoni, RE, 2007) |
| "Hyperuricemia has long been known to be associated with cardiovascular disease, and it is particularly common in people with hypertension, metabolic syndrome, or kidney disease." | 6.43 | Role of uric acid in hypertension, renal disease, and metabolic syndrome. ( Heinig, M; Johnson, RJ, 2006) |
| "Hyperuricemia is associated with hypertension, vascular disease, renal disease, and cardiovascular events." | 6.42 | Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? ( Feig, D; Herrera-Acosta, J; Johnson, RJ; Kanellis, J; Kang, DH; Kivlighn, S; Mazzali, M; Rodriguez-Iturbe, B; Tuttle, KR; Watanabe, S, 2003) |
| "Chloroquine (CQ) is an anti-inflammatory and disease-modifying anti-rheumatic drug (DMARD) utilized in treating autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus." | 5.91 | Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet. ( Cui, J; Hong, P; Li, Z; Lin, J; Nie, K; Wan, J; Wu, X; Zhang, X, 2023) |
| " However, BBR exhibits low bioavailability due to its extensive metabolism and limited absorption." | 5.62 | Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway. ( Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q, 2021) |
| "To assess the efficacy of febuxostat combined with hydration on contrast-induced nephropathy (CIN) in coronary heart disease patients with hyperuricemia undergoing percutaneous coronary intervention (PCI)." | 5.51 | Febuxostat combined with hydration for the prevention of contrast-induced nephropathy in hyperuricemia patients undergoing percutaneous coronary intervention: A CONSORT-compliant randomized controlled trial. ( He, Z; Li, M; Ma, G; Teng, W; Xia, Z; Zhai, X, 2022) |
| " However, there is no data about the effect of lowering uric acid level on renal functions and proteinuria in renal transplant recipients." | 5.51 | Effect of allopurinol drug use on GFR and proteinuria in patients with renal transplant recipients (ADOPTR study). ( Cingöz, M; Özdemir, O; Şahin, AZ; Usalan, C; Usalan, Ö, 2022) |
| "Preventing and treating renal fibrosis was an optimal treatment for hyperuricemia-induced kidney diseases." | 5.51 | Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Li, L; Liu, J; Ma, L; Pan, J; Shi, M, 2019) |
| "Hyperuricemia is associated with the development of chronic kidney disease." | 5.46 | Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats. ( Beibei, T; Huijuan, W; Jianchun, M; Rui, S; Xiaoxu, C; Xinghui, L, 2017) |
| " Gout is the most common inflammatory arthritis worldwide and starts with the crystallization of uric acid within the joints and soft tissues." | 5.41 | Amyloid A amyloidosis on medullary sponge kidney in a 28-year-old male with gout: A case report and literature review. ( Acikalin, MF; Kasifoglu, T; Yilmaz, F, 2023) |
| "A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal and metabolic diseases has been reported in many basic and epidemiological studies." | 5.41 | Update in uric acid, hypertension, and cardiovascular diseases. ( Ae, R; Andres-Hernando, A; Borghi, C; Hisatome, I; Kanbay, M; Kodama, T; Kuwabara, M; Lanaspa, MA, 2023) |
| "The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality but also acute coronary syndrome, stroke and heart failure." | 5.41 | The Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation. ( Agabiti Rosei, E; Angeli, F; Barbagallo, CM; Bernardino, B; Bombelli, M; Borghi, C; Cappelli, F; Casiglia, E; Cianci, R; Ciccarelli, M; Cicero, AFG; Cirillo, M; Cirillo, P; D'Elia, L; Dell'Oro, R; Desideri, G; Facchetti, R; Ferri, C; Galletti, F; Gesualdo, L; Giannattasio, C; Grassi, G; Iaccarino, G; Lippa, L; Mallamaci, F; Maloberti, A; Masi, S; Masulli, M; Mazza, A; Mengozzi, A; Muiesan, ML; Nazzaro, P; Palatini, P; Parati, G; Pauletto, P; Pontremoli, R; Pugliese, NR; Quarti-Trevano, F; Rattazzi, M; Reboldi, G; Rivasi, G; Russo, E; Salvetti, M; Tikhonoff, V; Tocci, G; Ungar, A; Verdecchia, P; Viazzi, F; Virdis, A; Volpe, M, 2023) |
| "Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L." | 5.37 | Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats. ( Chen, L; Lan, Z; Li, F; Li, P; Yang, Z; Zhang, C; Zhang, X; Zhou, Y, 2011) |
| "Hyperuricemia is common after kidney transplantation." | 5.35 | Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular risk. ( Bandukwala, F; Huang, M; Nash, MM; Prasad, GV; Zaltzman, JS, 2009) |
| "Insulin resistance was determined by the homeostasis model assessment (HOMA-IR)." | 5.35 | Uric acid: a surrogate of insulin resistance in older women. ( Chen, LK; Chiou, ST; Hwang, SJ; Lai, HY; Lin, MH, 2008) |
| "Gout is principally a disease of middle-aged men." | 5.26 | Uric acid crystal-induced nephropathy: evidence for a specific renal lesion in a gouty family. ( Cameron, JS; Dillon, MJ; Farebrother, DA; Pincott, JR; Simmons, HA; Warren, DJ, 1981) |
| "To determine the efficacy and safety of increasing the allopurinol dose above the proposed creatinine clearance-based dose in patients with gout." | 5.15 | Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment. ( Barclay, ML; Chapman, PT; Frampton, C; James, J; O'Donnell, JL; Stamp, LK; Zhang, M, 2011) |
| "Patients with arterial hypertension of the first-second degree with persistent elevated levels of uric acid in blood serum had significantly higher levels of ED markers: albuminuria, plasmic endothelin concentration." | 5.15 | [Clinical implication of endothelial dysfunction in patients with essential arterial hypertension and urate dysbolism with renal damage]. ( , 2011) |
| "The purpose of this study was to compare urate-lowering (UL) efficacy and safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA) > or = 8." | 5.14 | The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. ( Becker, MA; Espinoza, LR; Lademacher, C; Lloyd, E; MacDonald, P; Schumacher, HR; Wells, AF, 2010) |
| "72 cases of gouty renal damage were randomly divided into a treatment group of 42 cases and a control group of 30 cases to observe the therapeutic effects and the changes in 24-hour urinary protein content, blood creatinine, uric acid and urea nitrogen in blood before treatment and one month after treatment." | 5.11 | Clinical analysis for the acupuncture treatment in 42 cases of gouty renal damage. ( Ma, X, 2004) |
| " These initial studies demonstrate that tienilic acid is safe and effective in the treatment of mild to moderate essential hypertension, salt and water retention states, including oedema associated with congestive cardiac failure or mild to moderate renal dysfunction, and in the management of elevated serum uric acid levels associated with gout." | 5.04 | Safety of tienilic acid. ( Beg, MA; Ragland, R, 1979) |
| "Gout is the most common form of inflammatory arthropathy and is caused by an excess of uric acid in the blood (hyperuricemia)." | 4.95 | Change gout: the need for a new approach. ( Punzi, L, 2017) |
| "Besides the well accepted need to treat hyperuricemia associated with gout, some large observational studies and small prospective therapeutic trials have suggested that treating asymptomatic hyperuricemia, especially by xanthine oxidase inhibition, the enzyme producing uric acid, could be beneficial for cardiovascular and renal risk prevention." | 4.93 | [HYPERURICEMIA AND POTENTIAL RISK OF CARDIOVASCULAR AND RENAL DISEASES]. ( Krzesinski, JM; Schils, R, 2016) |
| "Hyperuricemia (elevated serum uric acid) is prevalent, and an important mediator of gout, an increasingly common condition." | 4.93 | Hyperuricemia, the kidneys, and the spectrum of associated diseases: a narrative review. ( Jalal, DI, 2016) |
| " Depending on the purpose of the study, renal parameters including the glomerular filtration rate (GFR), proteinuria/albuminuria, hematuria, renal tubular markers, uric acid, bone mineral disorders, and anemia are examined." | 4.90 | [Renal disease-related clinical examination in a cohort study]. ( Konta, T, 2014) |
| "Elevated serum uric acid concentration is a common laboratory finding in subjects with metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events." | 4.89 | Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal? ( Kapusta, DR; Rasheed, K; Reisin, E; Soltani, Z, 2013) |
| "Over the last decade, the biologic interference of uric acid with the cardiovascular (CV) system and the kidney has been intensively investigated, and several experimental studies in animal models and in vitro documented that hyperuricemia may trigger hypertension and incite endothelial dysfunction, vascular damage and renal disease." | 4.89 | Uric acid, hypertension, and cardiovascular and renal complications. ( Mallamaci, F; Zoccali, C, 2013) |
| "Traditionally, serum uric acid (SUA) has been implicated in acute gouty arthritis or chronic gouty arthropathy." | 4.89 | Hyperuricaemia: more than just a cause of gout? ( Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP, 2013) |
| "A number of epidemiological studies have reported an association between serum uric acid levels and a wide variety of high-risk conditions including hypertension, insulin resistance, and kidney and cerebro-cardiovascular disease." | 4.88 | Cardiovascular and renal effects of hyperuricaemia and gout. ( Leoncini, G; Pontremoli, R; Viazzi, F, 2012) |
| " Fructose induces systemic hypertension through several mechanisms mainly associated with deleterious effects on target organs (kidney, endothelium, heart) exerted by the byproducts of its metabolism, such as uric acid." | 4.87 | Dietary fructose and hypertension. ( Jalal, D; Johnson, RJ; Madero, M; Perez-Pozo, SE; Sánchez-Lozada, LG, 2011) |
| "Both elevated levels of uric acid and non-alcoholic fatty liver disease (NAFLD) have been associated with increased vascular risk." | 4.87 | Hyperuricaemia and non-alcoholic fatty liver disease (NAFLD): a relationship with implications for vascular risk? ( Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP, 2011) |
| " However, emerging data suggest that elevated uric acid (UA) is actually one of the most important factors for cardiovascular disease and that it also plays a significant role in the development of renal disease and metabolic syndrome." | 4.87 | Uric acid as a cardiometabolic risk factor: to be or not to be. ( Afsar, B; Covic, A; Kanbay, M, 2011) |
| "High uric acid (UA) levels can cause gout, urolithiasis and acute and chronic nephropathy, all of which are due to the deposit of urate crystals." | 4.87 | Is there anything good in uric acid? ( Alvarez-Lario, B; Macarrón-Vicente, J, 2011) |
| "After uric acid was recognized as the causative factor in gout, increased prevalence of renal disease and hypertension in this patient population caught the attention of the medical community." | 4.86 | Uric acid in hypertension and renal disease: the chicken or the egg? ( Covic, A; Dogan, E; Kanbay, M; Lanaspa, MA; Solak, Y, 2010) |
| "Elevated serum uric acid is a marker for decreased renal function, may have a mechanistic role in the incidence and progression of renal functional decline and likely has a causal role in hypertension and vascular disease." | 4.85 | Uric acid: a novel mediator and marker of risk in chronic kidney disease? ( Feig, DI, 2009) |
| "Epidemiological and metabolic studies have indicated an association between uric acid nephrolithiasis and insulin resistance." | 4.82 | Novel insights into the pathogenesis of uric acid nephrolithiasis. ( Cameron, MA; Maalouf, NM; Moe, OW; Sakhaee, K, 2004) |
| "This article critically evaluates the clinical evidence regarding the influence of uric acid on hypertension, cardiovascular disease, and kidney disease." | 4.82 | Clinical evidence for the influence of uric acid on hypertension, cardiovascular disease, and kidney disease: a statistical modeling perspective. ( Short, RA; Tuttle, KR, 2005) |
| "Although hyperuricemia has long been associated with renal disease, uric acid has not been considered as a true mediator of progression of renal disease." | 4.82 | Uric acid and chronic renal disease: possible implication of hyperuricemia on progression of renal disease. ( Kang, DH; Nakagawa, T, 2005) |
| "Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism." | 4.77 | Hyperuricemia and gout. ( German, DC; Holmes, EW, 1986) |
| "Benzbromarone1 is a benzofuran derivative which lowers serum urate and increases urinary urate excretion in normal, hyperuricaemic and gouty subjects." | 4.75 | Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| " Serum uric acid to albumin ratio (UAR) is a novel marker, which is associated with acute kidney injury in intensive care unit patients." | 4.31 | Serum Uric Acid to Albumin Ratio Can Predict Contrast-Induced Nephropathy in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention. ( Akbulut, T; Çınar, T; Şaylık, F; Selçuk, M, 2023) |
| "Uric acid has promoted renal fibrosis and inflammation in experimental studies, but some studies have shown nephroprotective effects due to alleviated oxidative stress." | 4.31 | Moderate hyperuricaemia ameliorated kidney damage in a low-renin model of experimental renal insufficiency. ( Eräranta, A; Honkanen, T; Kurra, V; Lakkisto, P; Mustonen, J; Myllymäki, J; Paavonen, T; Pörsti, I; Riutta, A; Tikkanen, I, 2023) |
| "Correlation influence factor analysis of gout patients' serum uric acid (SUA) levels, their examination fees, and various complications were explored." | 4.31 | Association between serum uric acid levels of patients with gout and their complications and examination fees: A cross-sectional analysis. ( Dang, W; Liu, J; Wang, J; Xu, D; You, L; Zhao, L, 2023) |
| "Hyperuricemic nephropathy may be induced by the elevation and accumulation of uric acid in kidney after hyperuricemia, which leads to kidney residential cells apoptosis and inflammation." | 4.31 | Renal herb formula protects against hyperuricemic nephropathy by inhibiting apoptosis and inflammation. ( Feng, Y; Li, S; Tang, GY; Wang, N; Xu, L; Xu, XY; Xu, Y; Zhang, C, 2023) |
| "Hyperuricemia nephropathy (HN) is a metabolic disease characterized by tubular damage, tubulointerstitial fibrosis, and uric acid kidney stones and has been demonstrated to be associated with hyperuricemia." | 4.31 | Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats. ( Guo, J; Wang, S; Zhang, B; Zhang, P; Zhao, X; Zhou, X; Zhuang, Y, 2023) |
| "Uric acid is the final product of purine metabolism, and excessive serum uric acid can cause gouty arthritis and uric acid nephropathy." | 4.02 | Bmk9 and Uricase Nanoparticle Complex for the Treatment of Gouty Arthritis and Uric Acid Nephropathy. ( An, M; Fu, H; Han, T; Li, W; Wang, M, 2021) |
| "The current work explored the influences of nifuroxazide, an in vivo inhibitor of signal transducer and activator of transcription-3 (STAT-3) activation, on tubulointerstitial fibrosis in rats with obstructive nephropathy using unilateral ureteral obstruction (UUO) model." | 4.02 | Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation. ( Hassan, NME; Said, E; Shehatou, GSG, 2021) |
| "To investigate the incidence and potential risk factors for development of fenofibrate-associated nephrotoxicity in gout patients." | 4.02 | Effects of fenofibrate therapy on renal function in primary gout patients. ( Chen, Y; Cheng, X; Cui, L; Han, L; He, Y; Ji, A; Ji, X; Li, C; Li, H; Li, X; Liu, Z; Lu, J; Ma, L; Merriman, TR; Ren, W; Sun, W; Wang, C; Wang, X; Yuan, X; Zhang, H, 2021) |
| "Fisetin lowered uricemia, suppressed renal inflammatory response, and improved kidney fibrosis to protect against hyperuricemic nephropathy via modulation of STAT3 and TGF-β signaling pathways." | 4.02 | Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling. ( Fu, P; Guo, F; Ma, L; Ren, Q; Tao, S; Wang, B; Yang, L, 2021) |
| " The effects of API on renal function, inflammation, fibrosis, and uric acid (UA) metabolism in mice with HN were evaluated." | 4.02 | Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway. ( Cao, Y; Chen, Y; Huang, Q; Jiang, Y; Li, L; Li, Y; Luo, J; Pang, J; Wu, T; Zhang, L; Zhao, Z; Zhou, P, 2021) |
| " The present study assessed the ability of taurine (TAU) to alleviate or prevent AMK-induced nephrotoxicity if co-administrated with AMK focusing on inflammation, apoptosis, and fibrosis." | 4.02 | The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation. ( Azmy, A; El-Amir, A; Madbouly, N; Salama, A, 2021) |
| "Dotinurad is a selective urate reabsorption inhibitor (SURI), which selectively inhibits URAT1 to lower serum uric acid levels in patients with hyperuricemia." | 4.02 | Comparative study of a novel selective urate reabsorption inhibitor "dotinurad" among patient groups with different stages of renal dysfunction. ( Beppu, T; Hidaka, Y; Hosoya, T; Takahashi, T, 2021) |
| "Berberine (BBR) is an active component of Phellodendri Cortex (PC), which is a traditional Chinese medicine that has been prescribed clinically for hyperuricemia (HUA) for hundreds of years." | 4.02 | Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model. ( Chen, J; Huang, Z; Li, Q; Li, Y; Liu, D; Su, Z; Xie, J; Zeng, H; Zheng, J, 2021) |
| " The effects of phloretin on renal function, fibrosis, oxidative stress, inflammation, and UA metabolism in HUA mice were evaluated." | 3.96 | Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption. ( Chen, Y; Cheng, J; Cui, D; Li, L; Liu, J; Liu, S; Lu, Y; Mao, R; Tang, M; Wang, C; Yuan, Y; Zhao, M, 2020) |
| " The mechanism of development of hyperuricemia (defined, serum uric acid (UA) ≥ 5." | 3.96 | Hyperuricemia is associated with a lower glomerular filtration rate in pediatric sickle cell disease patients. ( Beach, I; Feig, D; Kaspar, CDW; Newlin, J; Sisler, I; Smith, W, 2020) |
| "Hyperuricemia (HUA) is a metabolic disease caused by the overproduction or underexcretion of uric acid (UA)." | 3.96 | Dendrobium officinalis six nostrum ameliorates urate under-excretion and protects renal dysfunction in lipid emulsion-induced hyperuricemic rats. ( Chen, SH; Chen, X; Ge, HZ; He, X; Jiang, ZT; Lei, SS; Li, B; Lv, GY; Su, J; Wang, HY; Yu, QX; Zheng, X, 2020) |
| "Hyperuricemia, defined as the presence of elevated serum uric acid (sUA), could lead to urate deposit in joints, tendons, kidney and other tissues." | 3.96 | Mechanistic Insights of Soluble Uric Acid-related Kidney Disease. ( Fu, P; Ma, L; Pan, J; Shi, M, 2020) |
| "Lesinurad (LESU) is a selective urate reabsorption inhibitor approved at 200 mg daily for use with a xanthine oxidase inhibitor (XOI) to treat hyperuricaemia in gout patients failing to achieve target serum urate on XOI." | 3.91 | Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. ( Baumgartner, S; Goldfarb, DS; Jalal, D; Pillinger, M; Saag, KG; Schechter, BM; Terkeltaub, R; Valiyil, R; White, WB, 2019) |
| "The aim of this study was to assess the association between serum uric acid concentration (SUAC) and the parameters of the metabolic syndrome (MetS) and insulin resistance (IR)." | 3.91 | Associations Between Serum Uric Acid Concentrations and Cardiometabolic Risk and Renal Injury in Obese and Overweight Children ( Ersoy, B; Özalp Kızılay, D; Şen, S, 2019) |
| "Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension." | 3.88 | Sex-related relationships between uric acid and target organ damage in hypertension. ( Casati, M; Falbo, R; Giannattasio, C; Grassi, G; Maggioni, S; Maloberti, A; Nava, S; Occhi, L; Panzeri, F; Signorini, S; Triglione, N, 2018) |
| " Both Diosmin and Crocin improved insulin resistance, decreased blood pressure, uric acid, lipoproteins and blocked diabetic nephropathy as indicated by reduction of albumin excretion rate and albumin/creatinine ratio." | 3.88 | Diosmin and crocin alleviate nephropathy in metabolic syndrome rat model: Effect on oxidative stress and low grade inflammation. ( El Fayoumi, HM; El-Fawal, R; Mahmoud, MF, 2018) |
| "Uric acid (UA) has been associated with renal fibrosis and progression of chronic kidney disease." | 3.85 | Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney. ( De Paul, AL; Latini, A; Mukdsi, JH; Remor, A; Romero, CA; Torres, AI, 2017) |
| " Cox regression analysis showed that the baseline clinical and biochemical variables which associated with MACE were age, being illiterate, a widow or widower, and/or economically dependent, having triple vessel disease, stent implantation, anemia, and/or diabetes mellitus, waist to hip ratio (WHR), diastolic blood pressure, fasting glucose, total cholesterol, high-density lipoprotein cholesterol (HDL-C), creatinine, estimated glomerular filtration rate (eGFR), red blood cell count, hemoglobin, hematocrit, and mean corpuscular-hemoglobin concentration (MCHC) in ACS patients, and age, malnourished, and/or economically dependent, taking hypoglycemic medication, having triple vessel disease, stent implantation, anemia, diabetes mellitus, and/or hypertension, WHR, fasting glucose, HDL-C, uric acid, creatinine, eGFR, high-sensitivity C-reactive protein, mean corpuscular volume, and MCHC in elective PCI patients." | 3.85 | The burden of major adverse cardiac events in patients with coronary artery disease. ( Chung, FM; Hsu, CC; Hung, WC; Lee, YJ; Lu, LF; Lu, YC; Tsai, IT; Wang, CP; Wu, CC; Yu, TH, 2017) |
| "To explore the effects of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility (PR) on uric acid metabolism and the expression of urinary neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in rats with hyperuricemia." | 3.85 | Effect of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility on uric acid metabolism and urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in rats with hyperuricemia. ( Han, B; Hu, XG; Huang, HZ; Lei, M; Li, Z; Shi, W; Zhou, XM; Zhu, CX, 2017) |
| " The associations between serum uric acid (SUA) and hypertension, kidney disease, and coronary heart disease have been recognized." | 3.85 | Increased childhood BMI is associated with young adult serum uric acid levels: a linkage study from Japan. ( Komatsu, H; Kuwahara, E; Maejima, F; Murakami, Y; Nakazawa, A; Nishigaki, Y; Nishiwaki, Y; Okamura, T; Ushiku, H, 2017) |
| "The aim of this study was to evaluate relationships between serum uric acid (SUA) and newly emergent acute myocardial infarction (AMI), congestive heart failure (CHF), coronary artery disease (CAD), composite cardiovascular (CV) events (AMI, CHF, CAD), hypertension, hyperlipidemia, and renal disease in gout patients." | 3.85 | Evaluation of the Relationship Between Serum Uric Acid Levels and Cardiovascular Events in Patients With Gout: A Retrospective Analysis Using Electronic Medical Record Data. ( Bienen, EJ; Essex, MN; Hopps, M; Makinson, GT; Mardekian, J; Udall, M, 2017) |
| "Although aspirin-clopidogrel combination is more useful for acute coronary syndrome (ACS), the renal safety of this combination had not been established." | 3.83 | Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome. ( Baber, M; HamidAkash, MS; Hussain, SB; Irfan, M; Qadir, MI; Rehman, A, 2016) |
| "Longitudinal changes in uric acid levels were independently associated with the renal function decline in elderly patients with hypertension." | 3.83 | Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up. ( Chen, H; Huang, F; Lin, C; Lin, F; Zhang, H; Zhu, P, 2016) |
| "Hyponatremia associated with high urinary fractional excretion of uric acid which persists after serum sodium is corrected is the cardinal feature of salt losing nephropathy (SLN)." | 3.83 | Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury? ( Johnson, RJ; Lanaspa, MA; Lee, SK; Sánchez-Lozada, LG, 2016) |
| "At high altitude, increased γGT levels were associated with hyperglycemia; increased uric acid levels were associated with overweight/obesity, hemoglobin, dyslipidemia, high blood pressure and kidney disease." | 3.81 | Increased levels of serum γ-glutamyltransferase and uric acid on metabolic, hepatic and kidney parameters in subjects at high altitudes. ( Gonzales, GF; Tapia, V, 2015) |
| "We recruited 43 chronic kidney disease (CKD) patients who did not receive RAS blockers and antihyperuricaemic drugs, and investigated the relationship among serum uric acid (sUA) levels, the circadian rhythm of urinary angiotensinogen (U-AGT) excretion levels, and the levels of albuminuria (U-ACR) and proteinuria (U-P/Cr)." | 3.81 | Hyperuricaemia is associated with renal damage independently of hypertension and intrarenal renin-angiotensin system activation, as well as their circadian rhythms. ( Ishigaki, S; Isobe, S; Iwakura, T; Kato, A; Ohashi, N; Ono, M; Sakao, Y; Tsuji, N; Tsuji, T; Yasuda, H, 2015) |
| "In the univariate analysis, the major risk factors for kidney dysfunction in the patients with the cardio-cerebrovascular disease were age, gender, hypertension, diabetes mellitus, dyslipidemia and serum uric acid." | 3.80 | High prevalence and risk factors for kidney dysfunction in patients with atherosclerotic cardio-cerebrovascular disease. ( Bao, YS; Ji, Y; Jia, XB; Na, SP; Yang, J; Zhao, SL, 2014) |
| "While the prevalence of gout was calculated by counting patients with this diagnosis hyperuricemia was inferred in patients taking allopurinol at hospital admission or discharge, on the assumption that this drug was only prescribed owing to the finding of high serum levels of uric acid." | 3.80 | Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly. ( Conca, A; Corrao, S; Djade, CD; Franchi, C; Mannucci, PM; Marcucci, M; Marengoni, A; Nobili, A; Pasina, L; Salerno, F; Tettamanti, M, 2014) |
| "We assessed the relationship between contrast-induced nephropathy (CIN) and SYNTAX score (SS) and serum uric acid (SUA) levels in patients with ST elevation myocardial infarction (STEMI)." | 3.80 | Contrast-induced nephropathy in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention. ( Çayli, M; Elbasan, Z; Gür, M; Içen, YK; Kivrak, A; Kuloğlu, O; Özdogru, I; Şahin, DY; Türkoglu, C; Yildirim, A, 2014) |
| " We calculated the mean values for proteinuria and serum phosphate, calcium, uric acid, and PTH, as well as 24-hour urinary excretion of urea nitrogen over time for each patient." | 3.79 | Factors related with the progression of chronic kidney disease. ( Abad, S; Ampuero, J; Aragoncillo-Sauco, I; Barraca, D; López-Gómez, JM; Ruiz-Caro, C; Vega-Martínez, A; Verdalles-Guzmán, Ú; Yuste, C, 2013) |
| " The effect of preventing hyperuricemia was determined by concomitant treatment with a xanthine oxidase inhibitor, allopurinol (CsAALP), or with a uricosuric, benzbromarone (CsABENZ), in drinking water." | 3.78 | Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. ( Johnson, RJ; Mazali, FC; Mazzali, M, 2012) |
| " Blood urea nitrogen (BUN), serum creatinine (Scr), uric acid (UA) and proteinuria were evaluated." | 3.78 | Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model. ( He, J; Pei, X; Sun, S; Wang, C; Wang, Y; Wu, J; Yu, M; Zhao, W; Zhu, B, 2012) |
| "To examine the association between renal function, serum uric acid and markers of both pro-inflammatory and prothrombotic state in patients with diabetes mellitus (DM), metabolic syndrome and coronary artery disease." | 3.77 | Uric acid as a link between renal dysfunction and both pro-inflammatory and prothrombotic state in patients with metabolic syndrome and coronary artery disease. ( Buraczyńska, MJ; Kondracki, B; Rychta, E; Waciński, P; Wysokiński, A; Zapolski, T, 2011) |
| " Acetaminophen is a commonly used analgesic and antipyretic agent which, at high doses, causes liver and kidney necrosis in man and animals." | 3.77 | Evaluation of phytoconstituents and anti-nephrotoxic and antioxidant activities of Monochoria vaginalis. ( Kumar, BS; Kumar, RP; Palani, S; Raja, S; Selvaraj, R, 2011) |
| "The prevalence of albuminuria increases gradually with uric acid elevation." | 3.77 | [The relationship between urinary albumin excretion and serum uric acid in general population]. ( Cai, JF; Fan, XH; Gao, BX; Li, H; Li, JH; Li, XM; Li, XW; Liu, LL; Liu, XJ; Meng, QY; Mou, LJ; Wang, HY; Wu, JX, 2011) |
| " Hyperuricemia was defined if serum uric acid was ≥ 416." | 3.77 | Elderly renal transplant recipients and renal dysfunction: a risk factor for hyperuricemia. ( Einollahi, B; Einollahi, H; Rostami, Z, 2011) |
| " It specifically addressed the hypotheses that renal dysfunction in these patients may associate with the presence of insulin resistance, dyslipidaemia, uric acid levels and/or current levels of systemic inflammation." | 3.76 | Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis. ( Antonopoulos, I; Daoussis, D; Douglas, KM; John, H; Kitas, GD; Nightingale, P; Panoulas, VF; Toms, TE; Wong, P, 2010) |
| " In our study, calcium and uric acid abnormalities were the most common, and vesicoureteral reflux seemed to be the most common urological abnormality which led to urinary stasis and calculus formation." | 3.76 | Metabolic factors associated with urinary calculi in children. ( Alamdaran, SA; Naseri, M; Varasteh, AR, 2010) |
| " The cut-off point varied in subjects with various cardiovascular risk profiles such as serum uric acid level, gender or hypertension." | 3.76 | Very low-grade albuminuria reflects susceptibility to chronic kidney disease in combination with cardiovascular risk factors. ( Ahn, JM; Chae, DW; Chin, HJ; Heo, NJ; Kim, S; Lee, TW; Na, KY, 2010) |
| " We examined the association between uric acid levels and various clinical parameters, including the components of metabolic syndrome, in essential hypertension." | 3.76 | Association of uric acid with risk factors for chronic kidney disease and metabolic syndrome in patients with essential hypertension. ( Anzawa, R; Fujii, T; Seki, S; Tsutsui, K; Yamazaki, K; Yoshimura, M, 2010) |
| "We developed a point system to estimate chronic kidney disease risk at 4 years using the following variables: age (8 points), body mass index (2 points), diastolic blood pressure (2 points), and history of type 2 diabetes (1 point) and stroke (4 points) for the clinical model, with the addition of uric acid (2 points), postprandial glucose (1 point), hemoglobin A1c (1 point), and proteinuria 100 mg/dL or greater (6 points) for the biochemical model." | 3.76 | A prediction model for the risk of incident chronic kidney disease. ( Chen, MF; Chien, KL; Hsu, HC; Lee, BC; Lee, YT; Lin, HJ, 2010) |
| "Familial Juvenile hyperuricemic nephropathy (FJHN, OMIM #162000) is a rare autosomal dominant disorder characterized by hyperuricemia with renal uric acid under-excretion, gout and chronic kidney disease." | 3.76 | A case of familial juvenile hyperuricemic nephropathy with novel uromodulin gene mutation, a novel heterozygous missense mutation in Korea. ( Kim, JK; Lee, DH; Lee, YK; Noh, JW; Oh, SE, 2010) |
| "The presence of hyperuricemia and renal function impairment, especially in the absence of urate stone formation is strongly suggestive of lead nephropathy." | 3.76 | Association of lead exposure, serum uric acid and parameters of renal function in Nigerian lead-exposed workers. ( Alasia, DD; Emem-Chioma, PC; Wokoma, FS, 2010) |
| " The adverse effects of ifosfamide include proximal tubular damage, and renal wasting of electrolytes, glucose and amino acids, Fanconi syndrome, rickets and osteomalacia have also been reported with ifosfamide treatment." | 3.75 | Children's toxicology from bench to bed--Drug-induced renal injury (2): Nephrotoxicity induced by cisplatin and ifosfamide in children. ( Chayama, K; Fujieda, M; Hayashi, A; Matsunaga, A; Sekine, T; Tauchi, H, 2009) |
| "In rats with hyperuricemia induced by 2% oxonic acid and 0." | 3.74 | Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia. ( Chen, K; Cui, WY; Liu, GS; Long, CL; Pan, ZY; Qin, XC; Wang, H; Zhang, YF, 2008) |
| "Changes in plasma uric acid concentration (UA, mumol/L) in postoperative and critical illness have pathophysiological and clinical relevance and may alter plasma antioxidant capacity." | 3.74 | Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients. ( Ardito, F; Chiarla, C; Giovannini, I; Giuliante, F; Nuzzo, G; Pallavicini, F; Vellone, M, 2007) |
| "To investigate if increased lipid peroxidation is involved in hypercholesterolemia-induced hypertension and renal injury, we examined the effects of allopurinol, a xanthine oxidase inhibitor, on these conditions." | 3.73 | Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats. ( Atarashi, K; Ishiyama, A; Minami, M; Omata, M; Takagi, M, 2005) |
| "We studied the serum phosphorus (P) level of 110 patients with multiple myeloma (MM) (age range 42-83 years, median 62 years) and evaluated the relationship between that and other prognostic factors." | 3.73 | Prognostic significance of the serum phosphorus level and its relationship with other prognostic factors in multiple myeloma. ( Arai, C; Fujimoto, Y; Izumi, H; Katoh, M; Kuraishi, Y; Nagase, D; Natori, K; Okuda, S; Sugasawa, Y; Umeda, M, 2006) |
| "To study effects of uric acid disbolism in combination with other metabolic disturbances on prevalence and clinical symptoms of arterial hypertension; contribution of uric acid nephropathy to its development." | 3.73 | [Relationships between arterial hypertension, metabolic disturbances and uric acid nephropathy]. ( Balkarov, IM; Britov, AN; Deev, AD; Eliseeva, NA, 2006) |
| " The cardinal clinical features in individuals with the uromodulin mutation included hyperuricemia, decreased fractional excretion of uric acid, and chronic interstitial renal disease leading to end-stage renal disease (ESRD) in the fifth through seventh decade." | 3.72 | Clinical characterization of a family with a mutation in the uromodulin (Tamm-Horsfall glycoprotein) gene. ( Bleyer, AJ; Deterding, E; Ganier, D; Gorry, MC; Hart, TC; McBride, D; Sandhu, J; Satko, SG; Shihabi, Z; Weller, N; Woodard, AS; Xu, L; Zhu, H, 2003) |
| "To analyse relationships between left ventricular myocardium mass (LVMM) and imbalance of uric acid metabolism in patients with arterial hypertension (AH)." | 3.71 | [Relationship between mass of the left ventricular myocardium and uric acid metabolic imbalance in patients with arterial hypertension]. ( Anikina, SA; Balkarov, IM; Donskov, AS; Feofanova, ID; Golub', GV; Prilepo, NA; Saltykova, NG; Sviderskaia, NS, 2001) |
| " Renal and ischemia/reperfusion injury parameters were studied, as well as malondialdehyde as a parameter for oxidative stress." | 3.71 | Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function. ( Aarts, LP; Driessen, AH; Gerritsen, WB; Haas, FJ; van Boven, WJ, 2001) |
| "We studied 34 apparently healthy children and 2 propositi from kindreds with familial juvenile hyperuricaemic nephropathy (FJHN) - a disorder characterised by early onset, hyperuricaemia, gout, familial renal disease and a similarly low urate clearance relative to glomerular filtration rate (GFR) [fractional excretion of uric acid (FEur) 5." | 3.70 | Presymptomatic detection of familial juvenile hyperuricaemic nephropathy in children. ( Cameron, JS; Dalton, N; Haycock, GB; McBride, MB; Moro, F; Ogg, CS; Raman, GV; Rees, L; Rigden, S; Simmonds, HA; Van't Hoff, W, 1998) |
| " The vast majority of these patients had a malignancy and were in danger of developing tumor lysis syndrome (TLS) and subsequent acute uric acid nephropathy (AUAN) and were unable to take oral allopurinol." | 3.70 | Allopurinol: intravenous use for prevention and treatment of hyperuricemia. ( Anderson, SA; Cederberg, D; Guaspari, A; Haase-Statz, S; Hohneker, JA; Smalley, RV, 2000) |
| "The N-acetyl-beta-D-glucosaminidase (NAG) activities and albumin levels in the urine of 32 patients with active rheumatoid arthritis treated with low-dose pulse methotrexate (MTX) have been investigated." | 3.69 | N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment. ( Swierkot, J; Szechiński, J; Wiland, P, 1997) |
| "In patients with healthy native kidneys, long-term cyclosporine therapy, even at a low dose (5 mg/kg per day), is nephrotoxic and is associated with a high incidence of hypertension." | 3.68 | Renal function and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmune uveitis. ( Aupetit, B; Baumelou, A; Benhmida, M; Deray, G; Jacobs, C; Le Hoang, P; Maksud, P, 1992) |
| "Hypotheses concerning the development of uric acid and gouty nephropathy suggest that the initiating disease mechanism involves an interaction between uric acid or monosodium urate monohydrate (MSUM) crystals and renal tubular epithelial cells." | 3.68 | Ultrastructural studies of the reaction of urate crystals with a cultured renal tubular cell line. ( Axelsen, RA; Cross, M; Emmerson, BT; Osborne, JM, 1991) |
| "Ten patients with gout, hypertension, and mild to moderate renal insufficiency were studied for possible lead nephropathy by measuring stimulated urinary lead excretion." | 3.67 | Occult lead intoxication in patients with gout and kidney disease. ( Cecere, FA; Saylor, RP; Wright, LF, 1984) |
| "A life-threatening toxicity syndrome consisting of an erythematous, desquamative skin rash, fever, hepatitis, eosinophilia, and worsening renal function in 78 patients receiving allopurinol is described." | 3.67 | Severe allopurinol toxicity. Description and guidelines for prevention in patients with renal insufficiency. ( Hande, KR; Noone, RM; Stone, WJ, 1984) |
| " Parameters measured included blood pressure, blood chemistry (serum creatinine, uric acid, blood urea nitrogen, blood glucose total cholesterol, and electrolytes), plasma renin activity, and plasma aldosterone concentration." | 3.67 | Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction. ( Saruta, T, 1989) |
| "Suprofen, a nonsteroidal anti-inflammatory drug, has been associated with the onset of acute flank pain, hematuria, and transient renal dysfunction after the ingestion of one or two doses, particularly in young males." | 3.67 | Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain. ( Abraham, PA; Halstenson, CE; Keane, WF; Matzke, GR; Opsahl, JA, 1988) |
| "Similarity of the morphological picture of gouty nephropathy and primary glomerulonephritides in which purine antagonists turned out to be effective, a positive effect of azathioprine (Az) and 6-mercaptopurine (MP) on purine metabolism, and changes in immunity indices revealed in gout (hyperproduction of immunoglobulins and circulating immune complexes) necessitates the use of antimetabolites in combined therapy of gout patients with proteinuric and latent types of nephropathy." | 3.67 | [Substantiation and effectiveness of the use of purine antagonists in gouty nephropathy]. ( Diadyk, AI; Nikolenko, IuI; Shpilevaia, NI; Siniachenko, OV; Vasilenko, IV, 1987) |
| "After a short survey of the purine metabolism, excretion of uric acid, theories of gout and urate nephropathy methodical references are given for the estimation of excretion of uric acid, a normal region on test persons was established and compared with other authors." | 3.66 | [Diagnostic value of renal urate excretion]. ( Häntzschel, U; Költzsch, V, 1978) |
| " Synthesis of 14C-labelled N-formyl glycinamide ribonucleotide by lymphocytes was measured in healthy control subjects and patients with primary gout or hyperuricaemia secondary to renal failure, with or without allopurinol therapy." | 3.66 | Purine biosynthesis de novo by lymphocytes in gout. ( Brami, M; Chanard, J; Funck-Brentano, JL; Kamoun, P, 1978) |
| "Chronic lead nephtropathy, secondary gout (lead-gout) and porphyrinuria may develop after long lasting professional exposure to lead." | 3.65 | [Chronic lead poisoning: Lead gout with giant tophi on the skin, nephrophathy and porphyrinopathy]. ( Künzig, M; Orfanos, CE, 1975) |
| "The relationship between the dosage of pancreatic extract and the excretion of uric acid was investigated in 29 patients with cystic fibrosis and exocrine pancreatic insufficiency." | 3.65 | Therapeutic approach to pancreatic extract-induced hyperuricosuria in cystic fibrosis. ( Kennedy, J; Linshaw, MA; Nouisa-Arvanitakis, S; Stapleton, FB, 1977) |
| "2%) showed macroscopic renal uric acid infarctions." | 3.65 | Uric acid infarctions in the kidneys of newborn infants. A study on the changing incidence and on oxypurine ratios. ( Dörner, K; Eigster, G; Grünitz, J; Harms, D; Manzke, H, 1977) |
| "Obstructive uric acid nephropathy, a potentially lethal complication of acute renal failure due to glomerulonephritis, is described and illustrated." | 3.65 | Acute lobular (membranoproliferative) glomerulonephritis with hyperuricemia and obstructive uric acid nephropathy. ( Allen, AC, 1976) |
| "Nine people from four families living in rural parts of Scotland have been found to suffer from clinical or biochemical effects of lead poisoning." | 3.65 | Lead poisoning in rural Scotland. ( Beattie, AD; Dagg, JH; Goldberg, A; Ronald, J; Wang, I, 1972) |
| "Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination with a xanthine oxidase inhibitor (XOI) in patients who have not achieved target serum uric acid (sUA) levels with an XOI alone." | 2.82 | Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers. ( Gillen, M; Kerr, B; Lee, CA; Shen, Z; Valdez, S; Zhou, D, 2016) |
| "Hyperphosphatemia is a significant risk factor for the development of ectopic calcification and coronary artery diseases in patients on hemodialysis (HD), and must be controlled with the use of phosphate binders." | 2.77 | Comparison of efficacy of the phosphate binders nicotinic acid and sevelamer hydrochloride in hemodialysis patients. ( Ahmadi, F; Khatami, MR; Lessan-Pezeshki, M; Shamekhi, F, 2012) |
| "Allopurinol treatment slowed down renal disease progression independently of age, gender, diabetes, C-reactive protein, albuminuria, and renin-angiotensin system blockers use." | 2.75 | Effect of allopurinol in chronic kidney disease progression and cardiovascular risk. ( Ampuero, J; Arroyo, D; de Vinuesa, SG; Goicoechea, M; Luño, J; Rincón, A; Ruiz-Caro, C; Verdalles, U, 2010) |
| " The lowest CsA dosage and shortest exposure time effect as well as unlimited renal monitoring are required in order to provide the best long-term renal outcome." | 2.73 | Renal outcome after ciclosporin-induced nephrotoxicity. ( Bagnis, CI; Bodaghi, B; Deray, G; du Montcel, ST; Jaudon, MC; Le Hoang, P; Mallet, A; Tostivint, I, 2007) |
| "Hyperuricemia is associated strongly with the development of hypertension, renal disease, and progression." | 2.72 | Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level. ( Kwan, TH; Leung, KT; Siu, YP; Tong, MK, 2006) |
| "Uric acid has been considered a key molecule in the pathogenesis of some conditions such as metabolic syndrome, hypertension, and kidney disease as it is produced by injured cells and promotes immune-inflammatory responses." | 2.66 | Uric acid and kidney damage in systemic lupus erythematosus. ( Dos Santos, M; Moresco, RN; Veronese, FV, 2020) |
| "Uric acid is an end product of purine metabolism in human beings." | 2.66 | Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator. ( Adomako, E; Moe, OW, 2020) |
| "Hypoalbuminemia and hyperuricemia are independently associated with the occurrence of CIN among the patients undergoing CAG and/or intervention." | 2.61 | Predictive Value of Hepatorenal Status in Contrast-Induced Nephropathy Among Patients Receiving Coronary Angiography and/or Intervention: A Systematic Review and Meta-Analysis. ( Chen, G; Huang, L; Lu, Y; Qin, Q; Wang, C; Zhang, E; Zhang, J, 2019) |
| "Hyperuricemia affects one out of five adults as a result of the Western diet, insulin resistance, and renal dysfunction." | 2.61 | Uric acid and hypertension: a focused review and practical recommendations. ( Borghi, C; Burnier, M; De Becker, B; van de Borne, P, 2019) |
| "Hyperuricemia has long been known to cause gout, and has recently been correlated with cardiovascular disease, hypertension, and renal disease." | 2.55 | The role of urate-lowering treatment on cardiovascular and renal disease: evidence from CARES, FAST, ALL-HEART, and FEATHER studies. ( Pontremoli, R, 2017) |
| "Uric acid has been implicated in the pathophysiology of renal disease; however renal clearance makes a causal relationship difficult to prove." | 2.52 | Uric Acid as a Marker of Kidney Disease: Review of the Current Literature. ( Asmar, A; Giordano, C; Karasik, O; King-Morris, K, 2015) |
| "Hyperuricemia is associated with hypertension, kidney disease, vascular and cardiovascular (CV) events." | 2.52 | Hyperuricemia, urate deposition and the association with hypertension. ( Borghi, C; Grassi, G; Mancia, G, 2015) |
| "Gout is a painful inflammatory arthritis associated with hyperuricemia, with a prevalence of almost 10 million in the USA." | 2.49 | The kidney in hyperuricemia and gout. ( Mount, DB, 2013) |
| "Proteinuria is the most sensitive marker of CKD progression in clinical practice, especially when combined with eGFR, but these have limitations." | 2.47 | Biomarkers in chronic kidney disease: a review. ( Coombes, JS; Cooper, MA; Fassett, RG; Gobe, GC; Hoy, WE; Venuthurupalli, SK, 2011) |
| "Hyperuricemia is considered to be a risk factor of not only gout but also renal and cardiovascular diseases, thus, it is important to use CCBs without adverse effect on uric acid metabolisms." | 2.46 | [Calcium antagonists: current and future applications based on new evidence. The mechanisms on lowering serum uric acid level by calcium channel blockers]. ( Hamada, T; Hisatome, I; Igawa, O; Mizuta, E; Shigemasa, C, 2010) |
| "Hyperuricemia is a prevalent finding in patients presenting metabolic syndrome, although its clinical meaning is still controversial and often underestimated." | 2.46 | Uric acid as a factor in the metabolic syndrome. ( Batista, MC; Borges, RL; Ribeiro, AB; Zanella, MT, 2010) |
| "Hyperuricemia has also been found to be an independent risk factor for cardiovascular disease and hypertension." | 2.44 | The role of hyperuricemia and gout in kidney and cardiovascular disease. ( Edwards, NL, 2008) |
| "Renal functional changes in diabetic nephropathy conventionally have been linked to progression of urinary albumin excretion." | 2.44 | Between hyperfiltration and impairment: demystifying early renal functional changes in diabetic nephropathy. ( Ficociello, LH; Krolewski, AS; Niewczas, MA; Perkins, BA; Rosolowsky, ET; Warram, JH, 2008) |
| "Uric acid is an antioxidant and perhaps helps to control blood pressure during a low Na+ diet through stimulation of the renin-angiotensin system." | 2.44 | Uric acid: bystander or culprit in hypertension and progressive renal disease? ( Menè, P; Punzo, G, 2008) |
| "In most women with preeclampsia, renal plasma flow and glomerular filtration rate are at most only modestly decreased as a consequence of increased afferent arteriolar resistance and/or reduced ultrafiltration coefficient." | 2.44 | Renal function during normal pregnancy and preeclampsia. ( Conrad, KP; Jeyabalan, A, 2007) |
| "Purine inborn errors of metabolism (IEM) are serious hereditary disorders, which should be suspected in any case of neonatal fitting, failure to thrive, recurrent infections, neurological deficit, renal disease, self-mutilation and other manifestations." | 2.44 | Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions. ( Aquino Neto, FR; de Oliveira, ML; Gomes, LN; Oliveira, CP; Scalco, FB; Simoni, RE, 2007) |
| "Hyperuricemia is commonly associated with traditional risk factors such as abnormalities in glucose metabolism, dyslipidemia, and hypertension." | 2.43 | Serum uric acid as a risk factor for cardiovascular and renal disease: an old controversy revived. ( Leoncini, G; Pontremoli, R; Ratto, E; Viazzi, F, 2006) |
| "Hyperuricemia has long been known to be associated with cardiovascular disease, and it is particularly common in people with hypertension, metabolic syndrome, or kidney disease." | 2.43 | Role of uric acid in hypertension, renal disease, and metabolic syndrome. ( Heinig, M; Johnson, RJ, 2006) |
| "Hyperuricemia is associated with hypertension, vascular disease, renal disease, and cardiovascular events." | 2.42 | Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? ( Feig, D; Herrera-Acosta, J; Johnson, RJ; Kanellis, J; Kang, DH; Kivlighn, S; Mazzali, M; Rodriguez-Iturbe, B; Tuttle, KR; Watanabe, S, 2003) |
| "The physiopathology of the renal colic is analyzed with its implications in the medical treatment." | 2.40 | Conservative management of ureteric stones. ( Roumeguere, T; Schulman, CC; Simon, J; Vaessen, C, 1997) |
| " In renal insufficiency, the drug must be used cautiously and in reduced dosage because increased serum concentration of oxipurinol, active metabolite of allopurinol, may induce severe side effect." | 2.39 | [Metabolic disorder of purine nucleotide in patients with renal disease]. ( Hosoya, T; Ichida, K; Ohno, I; Sakai, O, 1996) |
| "In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death." | 2.36 | Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980) |
| " The ideal uricase inhibitor for induction of hyperuricemia would be one which is irreversible, noncompetitive, and relatively nontoxic, so that its activity would be independent of high levels of uric acid, and effective inhibition could be attained at low dosage levels." | 2.36 | Use of the uricase-inhibited rat as an animal model in toxicology. ( Nera, EA; Stavric, B, 1978) |
| "Chloroquine (CQ) is an anti-inflammatory and disease-modifying anti-rheumatic drug (DMARD) utilized in treating autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus." | 1.91 | Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet. ( Cui, J; Hong, P; Li, Z; Lin, J; Nie, K; Wan, J; Wu, X; Zhang, X, 2023) |
| " Therefore, administration of xanthenone along with tacrolimus could be a promising therapeutic strategy to reduce the adverse effects and increase the tolerability to tacrolimus immunosuppressive therapy." | 1.72 | Impact of the ACE2 activator xanthenone on tacrolimus nephrotoxicity: Modulation of uric acid/ERK/p38 MAPK and Nrf2/SOD3/GCLC signaling pathways. ( Ali, FEM; Azouz, AA; Hersi, F; Hussein Elkelawy, AMM; Omar, HA, 2022) |
| "Hyperuricemia is a critical threat to human health, and conventional medical treatment only aims to treat acute gouty arthritis." | 1.72 | Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis. ( Chen, X; Lu, Y; Lu, Z; Meng, F; Pang, X; Zhang, L; Zhao, H; Zhou, L, 2022) |
| "Betaine treatment significantly attenuated arsenic-induced decrease in renal eNOS expression." | 1.72 | Betaine attenuates sodium arsenite-induced renal dysfunction in rats. ( Kaur, T; Pathak, D; Sharma, AK; Sharma, S; Singh, AP; Singh, B; Yadav, HN, 2022) |
| "Renal adverse effects were associated to lead fumes exposure." | 1.62 | Evaluation of the Role of KIM-1 in Detecting Early Nephrotoxicity in Lead-Exposed Workers. ( Ahmed, MH; Ayesh, NA; Fouad, MM; Hussein, AA; Kamal, MM, 2021) |
| " However, BBR exhibits low bioavailability due to its extensive metabolism and limited absorption." | 1.62 | Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway. ( Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q, 2021) |
| "Gallic acid is a phenolic compound that has antioxidant properties." | 1.62 | Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats. ( Heibati, F; Heidarian, E; Nouri, A, 2021) |
| "Hyperuricemia is an important problem also in healthy subjects and its prevalence could further increase if lower cut-off will be used." | 1.62 | Hyperuricemia prevalence in healthy subjects and its relationship with cardiovascular target organ damage. ( Bombelli, M; Brambilla, P; Cartella, I; Casati, M; Giannattasio, C; Grassi, G; Grasso, E; Maloberti, A; Milani, M; Occhi, L; Qualliu, E; Signorini, S; Sun, J; Tavecchia, G; Tognola, C; Vallerio, P, 2021) |
| "Gout is the most common inflammatory arthritis in adults." | 1.62 | Non-alcoholic fatty kidney disease (NAFKD): A novel disease that explains the etiology of hyperuricemia and gout in metabolic syndrome. ( Abrahim, M, 2021) |
| "Metabolic acidosis was induced for 2 or 7 days with NH4Cl, some animals also received the uricase inhibitor oxonic acid for comparison." | 1.56 | Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney. ( Anzai, N; Endou, H; Gottier Nwafor, J; Nowik, M; Wagner, CA, 2020) |
| "Hyperuricemia has been well studied in the past two decades, revealing mechanistic insights into UA homeostasis." | 1.56 | Effects of uric acid dysregulation on the kidney. ( Dissanayake, LV; Palygin, O; Spires, DR; Staruschenko, A, 2020) |
| "Rhein has protective effect on uric acid nephropathy (UAN)." | 1.56 | Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis. ( Hu, J; Wang, D; Wu, H; Yang, Z, 2020) |
| "Uric acid level is a risk factor for kidney disease." | 1.56 | Uric acid level and kidney function: a cross-sectional study of the Korean national health and nutrition examination survey (2016-2017). ( Choi, DW; Joo, HJ; Joo, JH; Kim, GR; Park, EC, 2020) |
| "Canagliflozin is a sodium glucose co-transporter 2 (SGLT2) inhibitor that is currently available for the management of type 2 diabetes mellitus." | 1.51 | Effect of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on cisplatin-induced nephrotoxicity in mice. ( Abdelrahman, AM; Al Suleimani, Y; Ali, BH; Ashique, M; Manoj, P; Nemmar, A; Shalaby, A, 2019) |
| "Preventing and treating renal fibrosis was an optimal treatment for hyperuricemia-induced kidney diseases." | 1.51 | Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Li, L; Liu, J; Ma, L; Pan, J; Shi, M, 2019) |
| "Hyperuricemia has been identified as an independent risk factor for chronic kidney disease (CKD) and is associated with the progression of kidney diseases." | 1.51 | Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia. ( Bao, W; Fang, L; Gu, H; Lin, T; Liu, N; Lu, J; Ma, S; Qiu, A; Shi, Y; Tao, M; Wang, Y; Xu, L; Zhuang, S, 2019) |
| "This hyponatremia is saline-responsive, but relapse can be frequently observed." | 1.51 | Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly . ( Decaux, G; Musch, W, 2019) |
| " The cellular mechanisms that lead to those outcomes require an increase in intracellular concentrations of uric acid inducing oxidative stress that then activates the synthesis and secretion of proinflammatory factors and vasoconstrictive substances, and diminishes the bioavailability of nitric oxide produced by eNOS." | 1.48 | The Pathophysiology of Uric Acid on Renal Diseases. ( Sánchez-Lozada, LG, 2018) |
| "Hyperuricemia is associated with the development of chronic kidney disease." | 1.46 | Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats. ( Beibei, T; Huijuan, W; Jianchun, M; Rui, S; Xiaoxu, C; Xinghui, L, 2017) |
| "Uric acid is a product of purine catabolism formed by the activity of xanthine-oxidase and prevalently excreted by the kidney." | 1.46 | [The uric acid cardio-nephropathy]. ( Bonino, B; Cappadona, F; Pontremoli, R; Viazzi, F, 2017) |
| "Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome." | 1.46 | Soluble Uric Acid Activates the NLRP3 Inflammasome. ( Barbuto, JA; Braga, TT; Branco, P; Camara, NO; Castoldi, A; Correa-Costa, M; Davanso, MR; Forni, MF; Franklin, BS; Hiyane, MI; Kowaltowski, AJ; Latz, E; Ramos, RN, 2017) |
| "Uric acid was included as a continuous and dichotomous (per receiving operating characteristic curve) variable." | 1.46 | Serum uric acid levels contribute to new renal damage in systemic lupus erythematosus patients. ( Alarcón, GS; Alfaro-Lozano, JL; Cucho-Venegas, JM; Gamboa-Cárdenas, RV; Medina, M; Pastor-Asurza, CA; Perich-Campos, RA; Reátegui-Sokolova, C; Rodriguez-Bellido, Z; Ugarte-Gil, MF; Zevallos, F, 2017) |
| "The prevalence of sickle cell trait is extremely high in sub-Saharan Africa." | 1.46 | Congolese children with sickle cell trait may exhibit glomerular hyperfiltration: A case control study. ( Aloni, MN; Ekulu, PM; Gini-Ehungu, JL; Lepira, FB; Makulo, JR; Ngiyulu, RM; Nseka, NM; Nsibu, CN, 2017) |
| "Acetaminophen (APAP) is an analgesic and antipyretic agent commonly known agent to cause hepatic and renal toxicity at a higher dose." | 1.43 | Ameliorative effect of naringin in acetaminophen-induced hepatic and renal toxicity in laboratory rats: role of FXR and KIM-1. ( Adil, M; Bodhankar, SL; Ghosh, P; Kandhare, AD; Raygude, KS; Venkata, S, 2016) |
| "Recurrent dehydration, such as commonly occurs with manual labor in tropical environments, has been recently shown to result in chronic kidney injury, likely through the effects of hyperosmolarity to activate both vasopressin and aldose reductase-fructokinase pathways." | 1.43 | Rehydration with soft drink-like beverages exacerbates dehydration and worsens dehydration-associated renal injury. ( Arellano-Buendía, AS; Bankir, L; Cristóbal, M; García-Arroyo, FE; Johnson, RJ; Lanaspa, MA; Madero, M; Osorio, H; Roncal-Jiménez, C; Sánchez-Lozada, LG; Soto, V; Tapia, E, 2016) |
| "Uric acid may cause renal damage, whereas adiponectin in some studies has been reported to have renoprotective properties." | 1.43 | The Association Between Adiponectin, Serum Uric Acid and Urinary Markers of Renal Damage in the General Population: Cross-Sectional Data from the Tromsø Study. ( Eggen, AE; Eriksen, BO; Jenssen, TG; Kronborg, JB; Melsom, T; Norvik, JV; Solbu, MD; Storhaug, HM; Zykova, SN, 2016) |
| "Hyperuricemia is a common symptom in adult population." | 1.43 | Familial juvenile hyperuricemic nephropathy as rare cause of dialysis-dependent chronic kidney disease-a series of cases in two families. ( Adamczyk, P; Beck, B; Dyga, K; Kaminska-Pajak, KA; Szczepańska, M; Tkaczyk, M; Zaniew, M, 2016) |
| "Hyperuricemia is characterized by inhibited nitric oxide system and enhanced synthesis of reactive oxygen species." | 1.42 | Uric acid levels and the risk of Contrast Induced Nephropathy in patients undergoing coronary angiography or PCI. ( Barbieri, L; Cassetti, E; De Luca, G; Marino, P; Schaffer, A; Suryapranata, H; Verdoia, M, 2015) |
| "Hyperuricemia is very common in industrialized countries and known to promote vascular smooth muscle cell proliferation." | 1.42 | Smaller caliber renal arteries are a novel feature of uromodulin-associated kidney disease. ( Adamczak, M; Blondin, D; Dekomien, G; Epplen, JT; Helmchen, U; Januszewicz, A; Januszewicz, M; Litwin, M; Matuszkiewicz-Rowińska, J; Michałowska, I; Prejbisz, A; Rump, LC; Sajnaga, D; Sellin, L; Szwench-Pietrasz, E; Więcek, A; Woznowski, M, 2015) |
| " Therefore, it could be concluded that ceftriaxone and/or ascorbic acid administration able to minimize the toxic effects of DLM through their free radical-scavenging and potent antioxidant activity." | 1.42 | Synergistic protective effects of ceftriaxone and ascorbic acid against subacute deltamethrin-induced nephrotoxicity in rats. ( Abdel-Daim, MM; El-Ghoneimy, A, 2015) |
| "Hyperuricemia has been considered to be a key risk factor for kidney disease." | 1.42 | Anti-hyperuricemic and nephroprotective effects of rhein in hyperuricemic mice. ( Ding, G; Guo, C; Huang, W; Li, N; Meng, Z; Tang, Z; Wang, Z; Xiao, W; Yan, Y; Yang, Z, 2015) |
| "Gefitinib treatment also inhibited hyperuricemia-induced activation of the TGF-β1 and NF-κB signaling pathways and expression of multiple profibrogenic cytokines/chemokines in the kidney." | 1.42 | EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy. ( Bao, W; Cheng, SB; Chin, YE; Liu, N; Qiu, A; Shi, Y; Wang, L; Xiong, C; Xu, L; Yan, H; Yang, T; Zhuang, S, 2015) |
| " B06-treated groups were given B06 by gavage at a dosage of 0." | 1.42 | [Protective effect of curcumin derivative B06 on kidney of type 2 diabetic rats]. ( Chen, GR; Chen, SM; Cheng, JG; Liu, WW; Liu, X; Wang, L; Zeng, CC, 2015) |
| "Gout is an inflammatory arthritis characterised by hyperuricemia, which, if poorly controlled, can lead to the development of tophi." | 1.42 | Ulcerated tophaceous gout. ( Filanovsky, MG; McNamara, MC; Sukhdeo, K, 2015) |
| "Rosiglitazone was administered orally at a dose of 8 mg/kg/day and PGDJ2 was given intraperitoneally at a dose of 30 μg/kg/day." | 1.40 | The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity. ( Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I, 2014) |
| "Hyperuricemia is known to be a risk factor for incident type 2 diabetes mellitus, but the absolute magnitude of the association is not known." | 1.39 | Relative and attributable diabetes risk associated with hyperuricemia in US veterans with gout. ( Akhras, KS; Krishnan, E; Liu, J; Marynchenko, M; Sharma, H; Shi, L; Tawk, R; Wu, EQ, 2013) |
| "Hyperuricemia is an independent risk factor for mortality, cardiovascular disease, and renal disease in general population." | 1.38 | Association of hyperuricemia with renal outcomes, cardiovascular disease, and mortality. ( Chang, JM; Chen, HC; Chen, SC; Chiu, YW; Hung, CC; Hwang, SJ; Kuo, MC; Lin, MY; Liu, WC; Yeh, SM, 2012) |
| " The long elimination half-life of mPEG-UHC in non-human primate (191." | 1.38 | Characterization, efficacy, pharmacokinetics, and biodistribution of 5kDa mPEG modified tetrameric canine uricase variant. ( Chen, Z; Fan, K; Hu, C; Liu, R; Luo, H; Ma, X; Min, Z; Wei, D; Yang, L; Zhang, C, 2012) |
| "Necrosis was assessed by acridine orange and ethidium bromide." | 1.37 | Pro-inflammatory and oxidative effects of noncrystalline uric acid in human mesangial cells: contribution to hyperuricemic glomerular damage. ( Borges, FT; Convento, MS; Dalboni, MA; Pessoa, E; Schor, N, 2011) |
| "Mulberroside A is a major stilbene glycoside of MORUS ALBA L." | 1.37 | Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice. ( Hu, LS; Kong, LD; Wang, CP; Wang, X; Wang, Y; Ye, JF; Zhang, X, 2011) |
| " The most frequently used maximal dosage of allopurinol was 100 mg/day at each stage." | 1.37 | Management of asymptomatic hyperuricaemia in patients with chronic kidney disease by Japanese nephrologists: a questionnaire survey. ( Fukuhara, S; Nakata, T; Nakaya, I; Namikoshi, T; Onishi, Y; Shibagaki, Y; Tsuruta, Y, 2011) |
| "Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L." | 1.37 | Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats. ( Chen, L; Lan, Z; Li, F; Li, P; Yang, Z; Zhang, C; Zhang, X; Zhou, Y, 2011) |
| "Uric acid level was associated with lower all-cause mortality (HR: 0." | 1.37 | Uric acid levels and all-cause and cardiovascular mortality in the hemodialysis population. ( Arrington, CJ; Karaboyas, A; Kleophas, W; Latif, W; Levin, NW; Marshall, MR; Pisoni, RL; Robinson, BM; Saran, R; Sen, A; Tong, L; Winchester, JF, 2011) |
| "Hyperuricemia is a common complication in organ transplant recipients, with a higher incidence in kidney and heart recipients." | 1.37 | Uric acid and transplantation. ( Mazali, FC; Mazzali, M, 2011) |
| "Uric acid was used as a test for liver disease before the advent of enzymology." | 1.37 | The utility of uric acid assay in dogs as an indicator of functional hepatic mass. ( Goddard, A; Hill, JM; Leisewitz, AL, 2011) |
| "We found a clear dose-response relation between serum uric acid and risk of early GFR loss in patients with type 1 diabetes." | 1.36 | High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up. ( Aschengrau, A; Doria, A; Eckfeldt, JH; Ficociello, LH; Galecki, AT; Krolewski, AS; Maselli, NJ; Niewczas, MA; Rosolowsky, ET; Stanton, RC; Warram, JH; Weinberg, JM, 2010) |
| "Hyperuricemia is common after kidney transplantation." | 1.35 | Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular risk. ( Bandukwala, F; Huang, M; Nash, MM; Prasad, GV; Zaltzman, JS, 2009) |
| "Hyperuricemia is a common finding in hypertensive patients, especially among those who are on diuretic therapy." | 1.35 | Uric acid as a marker for renal dysfunction in hypertensive women on diuretic and nondiuretic therapy. ( Batista, MC; Borges, RL; Hirota, AH; Quinto, BM; Ribeiro, AB; Zanella, MT, 2009) |
| "Insulin resistance was determined by the homeostasis model assessment (HOMA-IR)." | 1.35 | Uric acid: a surrogate of insulin resistance in older women. ( Chen, LK; Chiou, ST; Hwang, SJ; Lai, HY; Lin, MH, 2008) |
| "Uric acid levels were only higher in patients with progression of disease when patients with uric acid-lowering drugs were excluded from the analysis." | 1.35 | Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study. ( Kollerits, B; Kronenberg, F; Neyer, U; Ritz, E; Sturm, G, 2008) |
| "Few studies have evaluated the long-term use of MMF in liver transplanted children with renal dysfunction." | 1.34 | Mycophenolate mofetil promotes prolonged improvement of renal dysfunction after pediatric liver transplantation: experience of a single center. ( Ayoub, AA; Gibelli, NE; Maksoud, JG; Maksoud-Filho, JG; Pinho-Apezzato, ML; Santos, MM; Silva, MM; Tannuri, U; Velhote, MC, 2007) |
| "Kidney disease progression was defined as a decrease in estimated glomerular filtration rate (GFR) of 3 mL/min/1." | 1.34 | Relationship of uric acid with progression of kidney disease. ( Carney, JK; Chonchol, M; Fried, LF; Katz, R; Kestenbaum, B; Newman, AB; Sarnak, MJ; Shlipak, MG; Siscovick, DS, 2007) |
| "Renal function in women with severe preeclampsia was significantly impaired and highly correlated with systolic or diastolic blood pressure." | 1.33 | The correlation between renal function and systolic or diastolic blood pressure in severe preeclamptic women. ( Chen, DC; Chuang, J; Seow, KM; Tang, MH; Wang, YY, 2005) |
| " These CUA/Ccr relations demonstrated a gene dosage effect that corresponds with the difference in serum urate levels." | 1.32 | Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. ( Endou, H; Enomoto, A; Hikita, M; Hisatome, I; Hosoya, T; Hosoyamada, M; Ichida, K, 2004) |
| "Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk factor for progression." | 1.31 | A role for uric acid in the progression of renal disease. ( Feng, L; Han, L; Harris, R; Johnson, RJ; Kang, DH; Mazzali, M; Nakagawa, T; Truong, L; Watanabe, S, 2002) |
| "Hematuria was seen in 7 out of the 16 patients (44%), all of whom were females (58%)." | 1.30 | Hematuria in patients with renal hypouricemia. ( Hamada, N; Hiroe, K; Hisatome, I; Kato, T; Kinugawa, T; Manabe, I; Ogino, K; Ohtahara, A; Sato, R; Shigemasa, C; Shimoyama, M; Takeda, A; Tanaka, Y; Tsuboi, M; Yamamoto, Y; Yoshida, A, 1998) |
| "Cisplatin caused differential toxic effects on blood glucose and plasma urea, uric acid and creatinine levels." | 1.30 | Rehabilitating role of glutathione ester on cisplatin induced nephrotoxicity. ( Babu, E; Chandramohan, N; Ebrahim, AS; Sakthisekaran, D, 1999) |
| "13 patients had combination of hyperinsulinemia with obesity, dyslipidemia, arterial hypertension." | 1.30 | [Urate affection of kidneys and metabolic disturbances in hypertensive patients]. ( Anikina, SA; Balkarov, IM; Donskov, AS; Fadina, ZM; Feofanova, ID; Golub', GV; Goncharov, VS; Saltykova, NG, 1999) |
| "The latter ones involved oxaluria (28 children), uraturia (17 children), cystinuria (14 children), and phosphaturia (9 children)." | 1.28 | [Use of xidifon for prevention and treatment of nephropathies with metabolic disorders in children]. ( Dunaeva, IP; Gavriushova, LP; Iur'eva, EA; Korovina, NA; Kulakova, GI; Mumladze, EB; Rzhevskaia, ON; Tvorogova, TM, 1990) |
| "Gout is primarily a disease of middle-aged males and is unusual in females and adolescent males." | 1.28 | Precocious familial gout with reduced fractional urate clearance and normal purine enzymes. ( Calabrese, G; Cameron, JS; Davies, PM; Simmonds, HA, 1990) |
| "Pretreatment with choline chloride, PAH, furosemide and ethacrynic acid reduced the nephrotoxic action of CP in rat but did not prevent the accumulation of platinum in renal tissue which appeared to be a function of the dose injected to investigated animals." | 1.28 | Cisplatin: nephrotoxic action in vertebrates and its prevention. ( Bakhteeva, VT; Brovtsyn, VK; Myazina, EM; Reznik, LV, 1989) |
| " This study describes the observed adverse reactions in this group of patients not undergoing transplantation." | 1.27 | Side effects of systemic cyclosporine in patients not undergoing transplantation. ( Chan, CC; Nussenblatt, RB; Palestine, AG, 1984) |
| "Pyrazinamide (PZA) was used to study the renal handling of hypoxanthine, xanthine and uric acid in 2 normal subjects and in 4 patients with idiopathic renal hypouricemia; one patient was classified as having a postsecretory reabsorption defect, whereas the others were classified as having a presecretory reabsorption defect." | 1.27 | Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia. ( Akaoka, I; Fujimori, S; Itoh, H; Kanbayashi, T; Kaneko, K; Miyashita, H; Nakayama, Y; Oyama, H, 1988) |
| " However, the 30- to 60-day biologic half-life of rubidium has mandated careful studies of potential toxicity before engaging in long-term administration of this ion to depressive subjects." | 1.27 | Renal tolerance of rubidium chloride: short-term clinical evaluation. ( Gerace, S; Lenzi, A; Marchitiello, M; Meltzer, HL; Palla, R; Paternoster, G; Placidi, GF; Toschi, D; Tuoni, M, 1987) |
| "Gout is principally a disease of middle-aged men." | 1.26 | Uric acid crystal-induced nephropathy: evidence for a specific renal lesion in a gouty family. ( Cameron, JS; Dillon, MJ; Farebrother, DA; Pincott, JR; Simmons, HA; Warren, DJ, 1981) |
| "The prevalence of kidney stones has steadily risen during this century; passage of a calculus and a positive family history increase the probability of recurrence." | 1.26 | Kidney stones. ( Brickman, AS; Coburn, JW; Ehrlich, RM; Kleeman, CR; Lee, DB; Narins, RG, 1980) |
| "Coronary heart disease is the leading cause of death in the gouty and nongouty population." | 1.26 | Changing trends of mortality in gout. ( Talbott, JH; Yü, T, 1980) |
| "Hypertension was found in 18% of 65 patients with untreated gout, a lower prevalence than that previously reported." | 1.26 | Hypertension, renal function and gout. ( Gibson, T; Highton, J; Potter, CF; Simmonds, HA, 1979) |
| "Uric acid clearance was increased by benzbromarone from 3." | 1.26 | [The effect of benzbromaron in gout patients with limited kidney function]. ( Bresnik, W; Kuzmits, R; Müller, MM, 1979) |
| "Other causes of acute renal failure in persons with acute leukemia, but not observed in this patient group, are hypercalcemia and leukemic infiltration of the kidneys." | 1.26 | Acute renal failure in patients with acute leukemia. ( Eckman, LN; Lynch, EC, 1978) |
| "Uric acid excretion was only slightly affected by pyrazinamide, a drug which suppresses renal tubular uric acid secretion, and by probenecid, a drug which inhibits tubular uric acid reabsorption." | 1.26 | Familial hypouricemia due to isolated renal tubular defect. Attenuated response of uric acid clearance to probenecid and pyrazinamide. ( Benjamin, D; de Vries, A; Pinkhas, J; Sperling, O; Weinberger, A, 1977) |
| " The control of the hyperuricemia and gout has been satisfactorily accomplished in the Filipino patients with the long-term use of allopurinol, sometimes complemented with colchicine taken daily." | 1.25 | The Filipino and gout. ( Bayani-Sioson, PS; Torralba, TP, 1975) |
| "A nearly 72-old black male with sickle cell anemia suffered from heart failure, hypertension, chronic impaired kidney function with hyperuricemia and gout." | 1.25 | Long survival in sickle cell anemia. ( Huisman, TH; Sar, AV, 1975) |
| "Uric acid was increased 38 and 48% over the control values by doses of 4." | 1.25 | Nephrotoxicity of dietary ochratoxin A in broiler chickens. ( Hamilton, PB; Huff, WE; Wyatt, RD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 443 (46.10) | 18.7374 |
| 1990's | 99 (10.30) | 18.2507 |
| 2000's | 136 (14.15) | 29.6817 |
| 2010's | 206 (21.44) | 24.3611 |
| 2020's | 77 (8.01) | 2.80 |
| Authors | Studies |
|---|---|
| Ichida, K | 9 |
| Hosoyamada, M | 5 |
| Kimura, H | 1 |
| Takeda, M | 1 |
| Utsunomiya, Y | 1 |
| Hosoya, T | 14 |
| Endou, H | 6 |
| Hussein, AA | 1 |
| Ahmed, MH | 1 |
| Kamal, MM | 1 |
| Ayesh, NA | 1 |
| Fouad, MM | 1 |
| Lin, G | 1 |
| Yu, Q | 1 |
| Xu, L | 7 |
| Huang, Z | 3 |
| Mai, L | 1 |
| Jiang, L | 2 |
| Su, Z | 2 |
| Xie, J | 2 |
| Li, Y | 12 |
| Liu, Y | 7 |
| Lin, Z | 1 |
| Chen, J | 3 |
| Han, T | 1 |
| Wang, M | 1 |
| Li, W | 3 |
| An, M | 1 |
| Fu, H | 1 |
| Azouz, AA | 1 |
| Omar, HA | 1 |
| Hersi, F | 1 |
| Ali, FEM | 1 |
| Hussein Elkelawy, AMM | 1 |
| Ma, G | 2 |
| Li, M | 3 |
| Teng, W | 1 |
| He, Z | 2 |
| Zhai, X | 1 |
| Xia, Z | 1 |
| Usalan, Ö | 1 |
| Şahin, AZ | 1 |
| Özdemir, O | 1 |
| Cingöz, M | 1 |
| Usalan, C | 1 |
| Li, H | 7 |
| Zhang, H | 5 |
| Yan, F | 1 |
| He, Y | 4 |
| Ji, A | 2 |
| Liu, Z | 6 |
| Ji, X | 2 |
| Li, C | 3 |
| Şaylık, F | 1 |
| Çınar, T | 1 |
| Akbulut, T | 1 |
| Selçuk, M | 1 |
| Chen, JS | 1 |
| Wang, MX | 1 |
| Wang, MM | 1 |
| Zhang, YK | 1 |
| Guo, X | 2 |
| Chen, YY | 1 |
| Zhang, MQ | 1 |
| Sun, JY | 2 |
| Liu, YF | 1 |
| Liu, C | 6 |
| Borghi, C | 5 |
| Guaraldi, F | 1 |
| Bazid, HAS | 1 |
| Shoeib, MA | 1 |
| El-Sayed, S | 1 |
| Mostafa, MI | 1 |
| Shoeib, MM | 1 |
| Eldeen, ES | 1 |
| Zhao, H | 3 |
| Chen, X | 5 |
| Zhang, L | 8 |
| Meng, F | 2 |
| Zhou, L | 4 |
| Pang, X | 1 |
| Lu, Z | 1 |
| Lu, Y | 8 |
| Yang, C | 1 |
| Su, HY | 1 |
| An, N | 1 |
| Wu, HL | 1 |
| Guo, XY | 1 |
| Li, ZH | 1 |
| Chen, XC | 1 |
| Zhu, SP | 1 |
| Wu, D | 4 |
| Li, HY | 1 |
| Pan, QJ | 1 |
| Liang, D | 1 |
| Liu, HF | 1 |
| Kurra, V | 1 |
| Eräranta, A | 1 |
| Paavonen, T | 1 |
| Honkanen, T | 1 |
| Myllymäki, J | 1 |
| Riutta, A | 1 |
| Tikkanen, I | 1 |
| Lakkisto, P | 1 |
| Mustonen, J | 1 |
| Pörsti, I | 1 |
| Chen, ZX | 1 |
| Liu, HQ | 1 |
| Wu, ZH | 1 |
| He, JL | 1 |
| Zhong, HJ | 1 |
| Yilmaz, F | 1 |
| Acikalin, MF | 1 |
| Kasifoglu, T | 1 |
| Li, QQ | 1 |
| Yang, B | 1 |
| Chen, N | 2 |
| Gong, LL | 1 |
| Liang, RX | 1 |
| Wang, L | 7 |
| Yin, XJ | 1 |
| Theofilis, P | 1 |
| Vordoni, A | 1 |
| Tsimihodimos, V | 1 |
| Kalaitzidis, RG | 1 |
| Wang, J | 7 |
| Bu, X | 1 |
| Qiu, X | 1 |
| Zhang, X | 9 |
| Gui, J | 1 |
| Wang, Y | 8 |
| Wang, C | 9 |
| van Zanten, TC | 1 |
| Xie, S | 2 |
| Kamianowska, M | 1 |
| Kamianowska, A | 1 |
| Wasilewska, A | 2 |
| Dang, W | 1 |
| Zhao, L | 1 |
| Xu, D | 2 |
| Liu, J | 8 |
| You, L | 1 |
| Liu, P | 3 |
| Li, P | 3 |
| Chen, L | 6 |
| Hu, Y | 2 |
| Ma, Y | 3 |
| Wang, H | 9 |
| Kuwabara, M | 3 |
| Kodama, T | 1 |
| Ae, R | 1 |
| Kanbay, M | 7 |
| Andres-Hernando, A | 2 |
| Hisatome, I | 10 |
| Lanaspa, MA | 7 |
| Tang, GY | 1 |
| Li, S | 2 |
| Xu, Y | 2 |
| Zhang, C | 4 |
| Xu, XY | 1 |
| Wang, N | 2 |
| Feng, Y | 2 |
| Ruan, J | 1 |
| Ruan, F | 1 |
| Ding, X | 2 |
| Han, C | 2 |
| Huang, C | 1 |
| Zhong, H | 1 |
| He, C | 1 |
| Zuo, Z | 1 |
| Huang, J | 2 |
| Cui, J | 2 |
| Hong, P | 1 |
| Li, Z | 4 |
| Lin, J | 1 |
| Wu, X | 7 |
| Nie, K | 1 |
| Wan, J | 2 |
| Di Sessa, A | 1 |
| Passaro, AP | 1 |
| Colasante, AM | 1 |
| Cioffi, S | 1 |
| Guarino, S | 1 |
| Umano, GR | 1 |
| Papparella, A | 1 |
| Miraglia Del Giudice, E | 1 |
| Marzuillo, P | 1 |
| Maloberti, A | 3 |
| Mengozzi, A | 1 |
| Russo, E | 1 |
| Cicero, AFG | 1 |
| Angeli, F | 1 |
| Agabiti Rosei, E | 1 |
| Barbagallo, CM | 1 |
| Bernardino, B | 1 |
| Bombelli, M | 2 |
| Cappelli, F | 1 |
| Casiglia, E | 1 |
| Cianci, R | 1 |
| Ciccarelli, M | 1 |
| Cirillo, M | 1 |
| Cirillo, P | 3 |
| Desideri, G | 1 |
| D'Elia, L | 1 |
| Dell'Oro, R | 1 |
| Facchetti, R | 1 |
| Ferri, C | 1 |
| Galletti, F | 1 |
| Giannattasio, C | 3 |
| Gesualdo, L | 2 |
| Iaccarino, G | 1 |
| Lippa, L | 1 |
| Mallamaci, F | 2 |
| Masi, S | 1 |
| Masulli, M | 1 |
| Mazza, A | 1 |
| Muiesan, ML | 1 |
| Nazzaro, P | 1 |
| Parati, G | 1 |
| Palatini, P | 1 |
| Pauletto, P | 1 |
| Pontremoli, R | 6 |
| Pugliese, NR | 1 |
| Quarti-Trevano, F | 1 |
| Rattazzi, M | 1 |
| Reboldi, G | 1 |
| Rivasi, G | 1 |
| Salvetti, M | 1 |
| Tikhonoff, V | 1 |
| Tocci, G | 1 |
| Ungar, A | 1 |
| Verdecchia, P | 1 |
| Viazzi, F | 4 |
| Volpe, M | 1 |
| Virdis, A | 1 |
| Grassi, G | 4 |
| Zhou, X | 5 |
| Zhang, B | 1 |
| Zhao, X | 1 |
| Zhang, P | 2 |
| Guo, J | 2 |
| Zhuang, Y | 1 |
| Wang, S | 6 |
| Ko, J | 1 |
| Kang, HJ | 1 |
| Kim, DA | 1 |
| Kim, MJ | 2 |
| Ryu, ES | 1 |
| Lee, S | 1 |
| Ryu, JH | 1 |
| Roncal, C | 2 |
| Johnson, RJ | 31 |
| Kang, DH | 14 |
| Wilkinson, SL | 1 |
| Divers, SJ | 1 |
| Scope, A | 1 |
| Schwendenwein, I | 1 |
| Cui, D | 1 |
| Liu, S | 1 |
| Tang, M | 1 |
| Zhao, M | 1 |
| Mao, R | 1 |
| Yuan, Y | 1 |
| Li, L | 4 |
| Chen, Y | 9 |
| Cheng, J | 2 |
| Aslan, G | 1 |
| Afsar, B | 3 |
| Sag, AA | 1 |
| Camkiran, V | 1 |
| Erden, N | 1 |
| Yilmaz, S | 1 |
| Siriopol, D | 1 |
| Incir, S | 1 |
| You, Z | 1 |
| Garcia, ML | 1 |
| Covic, A | 4 |
| Cherney, DZI | 1 |
| Fujita, K | 1 |
| Yamada, H | 2 |
| Iijima, M | 1 |
| Kaspar, CDW | 1 |
| Beach, I | 1 |
| Newlin, J | 1 |
| Sisler, I | 1 |
| Feig, D | 3 |
| Smith, W | 1 |
| Gargouri, M | 2 |
| Akrouti, A | 2 |
| Magné, C | 2 |
| El Feki, A | 2 |
| Soussi, A | 2 |
| Yang, P | 1 |
| Hu, J | 6 |
| Zhang, Y | 13 |
| Gao, B | 1 |
| Wang, TTY | 1 |
| Granvogl, M | 1 |
| Yu, LL | 1 |
| Gottier Nwafor, J | 1 |
| Nowik, M | 1 |
| Anzai, N | 4 |
| Wagner, CA | 1 |
| Dissanayake, LV | 1 |
| Spires, DR | 1 |
| Palygin, O | 1 |
| Staruschenko, A | 2 |
| Arévalo-Lorido, JC | 1 |
| Carretero-Gómez, J | 1 |
| Robles, NR | 1 |
| Nakagawa, T | 10 |
| Roncal-Jimenez, C | 2 |
| Sanchez-Lozada, LG | 12 |
| Tolan, DR | 1 |
| Dos Santos, M | 1 |
| Veronese, FV | 1 |
| Moresco, RN | 1 |
| Yang, Z | 5 |
| Wu, H | 4 |
| Wang, D | 2 |
| Mishima, E | 1 |
| Miyazaki, M | 1 |
| Abe, T | 2 |
| Shi, Y | 6 |
| Tao, M | 3 |
| Ma, X | 4 |
| Huang, G | 3 |
| Qiu, A | 3 |
| Zhuang, S | 5 |
| Liu, N | 5 |
| Oliveira, IO | 1 |
| Mintem, GC | 1 |
| Oliveira, PD | 1 |
| Freitas, DF | 1 |
| Brum, CB | 1 |
| Wehrmeister, FC | 2 |
| Gigante, DP | 1 |
| Horta, BL | 1 |
| Menezes, AMB | 2 |
| Ray, EC | 1 |
| Nouri, A | 1 |
| Heibati, F | 1 |
| Heidarian, E | 1 |
| Haug, S | 1 |
| Schlosser, P | 1 |
| Teumer, A | 1 |
| Tin, A | 1 |
| Pattaro, C | 1 |
| Köttgen, A | 1 |
| Wuttke, M | 1 |
| Abouee-Mehrizi, A | 1 |
| Rasoulzadeh, Y | 1 |
| Mesgari-Abbasi, M | 1 |
| Mehdipour, A | 1 |
| Ebrahimi-Kalan, A | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 12 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 2 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 2 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
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| Albertazzi, A | 1 |
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| Holländer, E | 2 |
| Schwarczmann, P | 2 |
| Isomäki, H | 1 |
| Kersley, GD | 1 |
| Rosenberg, AL | 1 |
| Bergstrom, L | 1 |
| Troost, BT | 1 |
| Bartholomew, BA | 1 |
| Delbarre, F | 1 |
| Auscher, C | 1 |
| de Géry, A | 1 |
| Hamet, M | 1 |
| Paulus, HE | 1 |
| Coutts, A | 1 |
| Calabro, JJ | 1 |
| Ferrone, S | 1 |
| Zanella, A | 1 |
| Bianchi Porro, G | 1 |
| Flores, A | 1 |
| Ranzi, T | 1 |
| Drew, CD | 1 |
| al-Khalidi, UA | 1 |
| Aftimos, S | 1 |
| Musharrafieh, S | 1 |
| Khuri, NN | 1 |
| Bhambal, SA | 1 |
| Sharma, KS | 1 |
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| Kammerhuber, F | 1 |
| Gomirato Sandrucci, M | 2 |
| Castello, D | 2 |
| Rosmino, GC | 2 |
| Norelli, MT | 2 |
| Baroncelli, PG | 2 |
| Ménard, J | 2 |
| Better, OS | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Comparative Trial on the Effect of Febuxostat in Preventing Cerebral and Cardiorenovascular Events in Patients With Hyperuricemia[NCT01984749] | 1,000 participants (Anticipated) | Interventional | 2013-11-30 | Active, not recruiting | |||
| Paediatric Obesity and Cardiovascular Dysfunction: Searching for Early Markers of Damage[NCT03169257] | 100 participants (Actual) | Interventional | 2015-01-15 | Completed | |||
| The Effect of Acute Fructose Load in Patients With Chronic Kidney Disease and Patients With Type 2 Diabetes Compared to Healthy Subjects[NCT03157960] | 20 participants (Actual) | Interventional | 2012-02-01 | Completed | |||
| Study on the Effect of Hyperuricaemia on Chronic Renal Disease and Intervention[NCT03425708] | Phase 4 | 400 participants (Anticipated) | Interventional | 2017-01-01 | Recruiting | ||
| Effect of Allopurinol or Febuxostat to Prevent Contrast Induced Acute Kidney Injury (CI-AKI)[NCT03767322] | Phase 2 | 558 participants (Anticipated) | Interventional | 2018-12-05 | Not yet recruiting | ||
| Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept[NCT04012294] | Phase 3 | 200 participants (Anticipated) | Interventional | 2019-08-30 | Recruiting | ||
| [NCT02797028] | Phase 4 | 320 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| PERL: A Multicenter Clinical Trial of Allopurinol to Prevent GFR Loss in T1D[NCT02017171] | Phase 3 | 530 participants (Actual) | Interventional | 2014-02-28 | Completed | ||
| Novel Methods for Ascertainment of Gout Flares -A Pilot Study[NCT02855437] | 44 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| A Phase 3, Randomized, Multicenter, Double-Blind, Allopurinol-Controlled Study Assessing the Efficacy and Safety of Oral Febuxostat in Subjects With Gout.[NCT00430248] | Phase 3 | 2,269 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| Study Protocol for a Prospective Observational Study Investigating the Role of Luminal Pressure on Arteriovenous Fistula Maturation[NCT04017806] | 60 participants (Anticipated) | Observational | 2018-09-19 | Recruiting | |||
| Is Reiki Effective In Coping With the Symptoms Experienced by Patients Undergoing Hemodialysis?: Single-Blind Randomized Controlled Trial[NCT05833451] | 64 participants (Actual) | Interventional | 2022-03-07 | Completed | |||
| Effect of a Nutritional Supplement of Probiotics and/or Prebiotics vs Placebo on Serum Concentrations of Uremic Toxins and Inflammatory Cytokines in Automated Peritoneal Dialysis Patients.[NCT03770611] | 112 participants (Anticipated) | Interventional | 2019-01-07 | Not yet recruiting | |||
| Value of Uric Acid as Early Predictor of Lupus Nephritis in Assiut University Hospital[NCT05402735] | 100 participants (Anticipated) | Observational | 2022-06-15 | Recruiting | |||
| Uric Acid and Hypertension in African Americans[NCT00241839] | Phase 3 | 150 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| Influence of Food Liking of Adding Spices to Replace Dietary Sugar Using Sequential Monadic CLT Methodology[NCT03139552] | 150 participants (Actual) | Interventional | 2016-10-17 | Completed | |||
| Influence on Food Liking of Adding Spices to Replace Dietary Sugar[NCT03134079] | 160 participants (Actual) | Interventional | 2015-09-10 | Completed | |||
| Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women With Preeclampsia[NCT04298034] | Phase 3 | 300 participants (Anticipated) | Interventional | 2020-07-17 | Recruiting | ||
| Pediatric Hypertension Registry (PHREG)[NCT03305562] | 179 participants (Actual) | Observational [Patient Registry] | 2017-09-20 | Terminated (stopped due to Study was a pilot study and the investigators received funding to initiate the main study) | |||
| The Role of the Renin-Angiotensin System in Pediatric Primary Hypertension (PHRAS)[NCT03310684] | 160 participants (Anticipated) | Observational | 2018-12-03 | Active, not recruiting | |||
| Pancreatic Enzyme Replacement Therapy (PERT) for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer[NCT02985801] | Phase 1/Phase 2 | 16 participants (Actual) | Interventional | 2016-12-31 | Terminated (stopped due to Study was terminated due to difficulty in recruiting subjects.) | ||
| Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial[NCT03923933] | Phase 2 | 34 participants (Actual) | Interventional | 2019-06-18 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Geometric mean of urinary albumin excretion rate (AER) during the last three months of the treatment period (Visits 15 and 16), adjusted for the mean urinary AER at baseline. Results are expressed as least square means of the geometric means in each subject in each group. (NCT02017171)
Timeframe: Last three months of treatment period (Weeks 142 and 156)
| Intervention | ug/min (Least Squares Mean) |
|---|---|
| Allopurinol | 47.9 |
| Placebo | 37.4 |
Geometric mean of two urinary albumin excretion (AER) measurements at the end of the 2-month wash-out period following the 3-year treatment period, adjusted for the mean urinary AER at baseline. Results are expressed as least square means of the geometric means in each subject in each group. (NCT02017171)
Timeframe: End of the 2-month wash-out period following the 3-year treatment period (week 164)
| Intervention | ug/min (Least Squares Mean) |
|---|---|
| Allopurinol | 42.9 |
| Placebo | 31.7 |
Glomerular filtration rate (GFR) at 4 months after randomization, estimated from serum creatinine and cystatin C and adjusted for the eGFR at baseline. (NCT02017171)
Timeframe: 4 months after randomization (week 16)
| Intervention | ml/min/1.73 m2 (Least Squares Mean) |
|---|---|
| Allopurinol | 70.3 |
| Placebo | 70.0 |
Glomerular filtration rate time trajectory from baseline to end of the 2-month wash-out period (week 164) estimated from quarterly serum creatinine measurements (eGFR). eGFR slopes were estimated by a linear mixed-effects model for longitudinal eGFR measures using a multiple imputation technique for missing values. Positive values denote increasing eGFR over time, negative values denote declining eGFR over time. (NCT02017171)
Timeframe: Weeks 0, 4, 16, 32, 48, 64, 80, 96, 112, 128, 156, and 164 (from baseline to the end of washout period)
| Intervention | ml/min/1.73 m2/year (Least Squares Mean) |
|---|---|
| Allopurinol | -2.4 |
| Placebo | -2.1 |
Risk of cardiovascular events defined as the composite of CVD death (ICD-10 code I10 to I74.9), myocardial infarction, stroke (ischemic or hemorrhagic), coronary artery bypass grafting, or percutaneous coronary intervention in the allopurinol arm as compared to placebo.Results are expressed as the number of participants who experienced an event in each treatment group. The risk of an event in the allopurinol group as compared to the risk in the placebo group is expressed as hazard ratio (estimated by means of proportional hazard regression). (NCT02017171)
Timeframe: Up to the end of the 2-month wash-out period following the 3-year treatment period (week 0 to 164)
| Intervention | Participants (Count of Participants) |
|---|---|
| Allopurinol | 15 |
| Placebo | 9 |
Glomerular filtration rate (GFR) at the end of the 2-month wash-out period following the 3-year treatment period, measured by the plasma disappearance of non-radioactive iohexol (iGFR) and adjusted for the iGFR at baseline. (NCT02017171)
Timeframe: End of the 2-month wash-out period following the 3-year treatment period (week 164)
| Intervention | ml/min/1.73 m^2 (Least Squares Mean) |
|---|---|
| Allopurinol | 61.2 |
| Placebo | 61.2 |
Glomerular filtration rate (GFR) at the end of the 3-year treatment period, measured by the plasma disappearance of non-radioactive iohexol (iGFR) and adjusted for the iGFR at baseline. (NCT02017171)
Timeframe: End of the 3-yr treatment period (week 156)
| Intervention | ml/min/1.73 m2 (Least Squares Mean) |
|---|---|
| Allopurinol | 61.3 |
| Placebo | 61.0 |
Glomerular filtration rate time trajectory estimated from iohexol disappearance GFR (iGFR) measurements at weeks 0, 80, 156, and 164. iGFR slopes were estimated by a linear mixed-effects model for longitudinal iGFR measures using a multiple imputation technique for missing values. Positive values denote increasing GFR over time, negative values denote declining iGFR over time. (NCT02017171)
Timeframe: Weeks 0, 80, 156, and 164 (from baseline to the end of washout period)
| Intervention | ml/min/1.73 m2/year (Least Squares Mean) |
|---|---|
| Allopurinol | -3.0 |
| Placebo | -2.5 |
Risk of serum creatinine doubling or end stage renal disease (ESRD) in the allopurinol arm as compared to placebo. Results are expressed as the number of participants who experienced an event in each treatment group. The risk of an event in the allopurinol group as compared to the risk in the placebo group is expressed as hazard ratio (estimated by means of proportional hazard regression). (NCT02017171)
Timeframe: Up to the end of the 2-month wash-out period following the 3-year treatment period (Week 0 to Week 164)
| Intervention | Participants (Count of Participants) |
|---|---|
| Allopurinol | 13 |
| Placebo | 11 |
Feasibility ----Assessed by the percentage of participants completing answer IRV/RheumPRO queries. (NCT02855437)
Timeframe: 6 months
| Intervention | percentage of weekly response (Mean) |
|---|---|
| Interactive Voice Response | 81 |
| RheumPro Smartphone Application | 80 |
Percentage of total study population preferring IVR vs. RheumPRO (NCT02855437)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Interactive Voice Response | 3 |
| RheumPro Smartphone Application | 28 |
The percent change in serum urate from baseline to the Final visit was summarized. The final visit was the last visit at which a serum urate value was collected. (NCT00430248)
Timeframe: Baseline and Last Visit on treatment (up to 6 months)
| Intervention | percent change from baseline (Mean) |
|---|---|
| Febuxostat 40 mg QD | -33.1 |
| Febuxostat 80 mg QD | -40.6 |
| Allopurinol 200 mg or 300 mg QD | -31.3 |
Serum urate values were obtained at the Month 2 visit. The percent change in serum urate from baseline to the Month 2 visit was summarized. (NCT00430248)
Timeframe: Baseline and Month 2
| Intervention | percent change from baseline (Mean) |
|---|---|
| Febuxostat 40 mg QD | -35.1 |
| Febuxostat 80 mg QD | -44.5 |
| Allopurinol 200 mg or 300 mg QD | -33.8 |
Serum urate values were obtained at the Month 4 visit. The percent change in serum urate from baseline to the Month 4 visit was summarized. (NCT00430248)
Timeframe: Baseline and Month 4
| Intervention | percent change from baseline (Mean) |
|---|---|
| Febuxostat 40 mg QD | -34.9 |
| Febuxostat 80 mg QD | -45.5 |
| Allopurinol 200 mg or 300 mg QD | -34.5 |
Serum urate values were obtained at the Month 6 visit. The percent change in serum urate from baseline to the Month 6 visit was summarized. (NCT00430248)
Timeframe: Baseline and Month 6
| Intervention | percent change from baseline (Mean) |
|---|---|
| Febuxostat 40 mg QD | -35.6 |
| Febuxostat 80 mg QD | -45.1 |
| Allopurinol 200 mg or 300 mg QD | -34.4 |
The percentage of subjects with mild-to-moderate renal impairment whose serum urate was <6.0 mg/dL at the final visit was summarized. The final visit was the last visit at which a serum urate value was collected. (NCT00430248)
Timeframe: Last Visit on treatment (up to 6 months)
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 49.7 |
| Febuxostat 80 mg QD | 71.6 |
| Allopurinol 200 mg or 300 mg QD | 42.3 |
The percentage of subjects whose serum urate level was <6.0 mg/dL at the Final Visit was summarized. The Final Visit was the last visit at which a serum urate value was collected. (NCT00430248)
Timeframe: Last Visit on treatment (up to 6 months)
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 45.2 |
| Febuxostat 80 mg QD | 67.1 |
| Allopurinol 200 mg or 300 mg QD | 42.1 |
The percentage of subjects whose serum urate level was <4.0 mg/dL at the Final Visit was summarized. The Final Visit was the last visit at which a serum urate values was collected. (NCT00430248)
Timeframe: Last Visit on treatment (up to 6 months)
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 2.5 |
| Febuxostat 80 mg QD | 17.5 |
| Allopurinol 200 mg or 300 mg QD | 1.5 |
Serum urate values were obtained at the Month 2 visit. The percentage of subjects whose serum urate was <4.0 mg/dL at the Month 2 visit was summarized. (NCT00430248)
Timeframe: Month 2
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 2.1 |
| Febuxostat 80 mg QD | 17.5 |
| Allopurinol 200 mg or 300 mg QD | 1.5 |
Serum urate values were obtained at the Month 4 visit. The percentage of subjects whose serum urate was <4.0 mg/dL at the Month 4 visit was summarized. (NCT00430248)
Timeframe: Month 4
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 2.0 |
| Febuxostat 80 mg QD | 18.6 |
| Allopurinol 200 mg or 300 mg QD | 1.4 |
Serum urate values were obtained at the Month 6 visit. The percentage of subjects whose serum urate was <4.0 mg/dL at the Month 6 visit was summarized. (NCT00430248)
Timeframe: Month 6
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 3.1 |
| Febuxostat 80 mg QD | 20.3 |
| Allopurinol 200 mg or 300 mg QD | 1.8 |
The percentage of subjects whose serum urate level was <5.0 mg/dL at the Final Visit was summarized. The Final Visit was the last visit at which a serum urate values was collected. (NCT00430248)
Timeframe: Last Visit on treatment (up to 6 months)
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 16.5 |
| Febuxostat 80 mg QD | 44.0 |
| Allopurinol 200 mg or 300 mg QD | 13.2 |
Serum urate values were obtained at the Month 2 visit. The percentage of subjects whose serum urate was <5.0 mg/dL at the Month 2 visit was summarized. (NCT00430248)
Timeframe: Month 2
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 15.4 |
| Febuxostat 80 mg QD | 45.9 |
| Allopurinol 200 mg or 300 mg QD | 11.7 |
Serum urate values were obtained at the Month 4 visit. The percentage of subjects whose serum urate was <5.0 mg/dL at the Month 4 visit was summarized. (NCT00430248)
Timeframe: Month 4
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 15.0 |
| Febuxostat 80 mg QD | 51.6 |
| Allopurinol 200 mg or 300 mg QD | 13.5 |
Serum urate values were obtained at the Month 6 visit. The percentage of subjects whose serum urate was <5.0 mg/dL at the Month 6 visit was summarized. (NCT00430248)
Timeframe: Month 6
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 19.3 |
| Febuxostat 80 mg QD | 49.7 |
| Allopurinol 200 mg or 300 mg QD | 14.8 |
Serum urate values were obtained at the Month 2 visit. The percentage of subjects whose serum urate was <6.0 mg/dL at the Month 2 visit was summarized. (NCT00430248)
Timeframe: Month 2
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 49.1 |
| Febuxostat 80 mg QD | 74.1 |
| Allopurinol 200 mg or 300 mg QD | 43.2 |
Serum urate values were obtained at the Month 4 visit. The percentage of subjects whose serum urate was <6.0 mg/dL at the Month 4 visit was summarized. (NCT00430248)
Timeframe: Month 4
| Intervention | percentage of subjects (Number) |
|---|---|
| Febuxostat 40 mg QD | 47.1 |
| Febuxostat 80 mg QD | 75.2 |
| Allopurinol 200 mg or 300 mg QD | 45.5 |
Serum urate values were obtained at the Month 6 visit. The percentage of subjects whose serum urate was <6.0 mg/dL at the Month 6 visit was summarized. (NCT00430248)
Timeframe: Month 6
| Intervention | percentage of participants (Number) |
|---|---|
| Febuxostat 40 mg QD | 48.9 |
| Febuxostat 80 mg QD | 75.3 |
| Allopurinol 200 mg or 300 mg QD | 46.6 |
"The Diastolic BP was taken at Baseline and after 8-10 weeks of treatment or placebo while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol / placebo
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | 3.44 |
| B (Placebo) | -0.83 |
Subjects had 24 hr blood pressure monitoring (ABPM) at baseline and treatment end. The readings were averaged and the changes from baseline to treatment end were compared. (NCT00241839)
Timeframe: Baseline and end of treatment (8-10 weeks on allopurinol / placebo)
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | -5.9 |
| B (Placebo) | 0.90 |
"The systolic BP was taken at Baseline and after 8-10 weeks of treatment on placebo, while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol or placebo
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | 0.21 |
| B (Placebo) | -0.95 |
Subjects on allopurinol are expected to lower their uric acid levels relative to placebo. (NCT00241839)
Timeframe: Baseline UA levels compared to end of treatment levels (8-10 weeks on allopurinol / placebo)
| Intervention | mg/dl (Mean) |
|---|---|
| A (Allopurinol) | 2.29 |
| B (Placebo) | 0.14 |
Overall liking of apple crisp with a 9-point hedonic rating scale instrument (whereby 0 = dislike extremely and 9 = like extremely ) (NCT03139552)
Timeframe: Day of taste testing
| Intervention | score on likert rating scale (Mean) |
|---|---|
| Full Sugar Recipe | 7.31 |
| Reduced Sugar Recipe | 6.83 |
| Reduced Sugar Plus Spice Recipe | 7.22 |
Overall liking of oatmeal with a 9-point hedonic rating scale instrument (whereby 0 = dislike extremely and 9 = like extremely ) (NCT03139552)
Timeframe: day of taste testing
| Intervention | score on a likert rating scale (Mean) |
|---|---|
| Full Sugar Recipe | 6.84 |
| Reduced Sugar Recipe | 5.70 |
| Reduced Sugar Plus Spice Recipe | 6.15 |
Overall liking of tea with a 9-point hedonic rating scale instrument (whereby 0 = dislike extremely and 9 = like extremely ) (NCT03139552)
Timeframe: day of taste testing
| Intervention | score on a likert rating scale (Mean) |
|---|---|
| Full Sugar Recipe | 6.00 |
| Reduced Sugar Recipe | 5.62 |
| Reduced Sugar Plus Spice Recipe | 5.85 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 54 |
| Second Place Ranking | 63 |
| Third Place Ranking | 33 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 88 |
| Second Place Ranking | 39 |
| Third Place Ranking | 21 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 66 |
| Second Place Ranking | 41 |
| Third Place Ranking | 42 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 48 |
| Second Place Ranking | 60 |
| Third Place Ranking | 40 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 63 |
| Second Place Ranking | 44 |
| Third Place Ranking | 43 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 49 |
| Second Place Ranking | 50 |
| Third Place Ranking | 50 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 33 |
| Second Place Ranking | 43 |
| Third Place Ranking | 74 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: day of taste testing
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 12 |
| Second Place Ranking | 49 |
| Third Place Ranking | 87 |
Subjects ranked each recipe in order of likability as first, second or third. (NCT03139552)
Timeframe: Day of taste testings
| Intervention | Participants (Count of Participants) |
|---|---|
| First Place Ranking | 34 |
| Second Place Ranking | 58 |
| Third Place Ranking | 57 |
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -3.4 |
| Treatment Grup | -13.5 |
Decrease in extracellular water measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.15 |
| Treatment Grup | 2.55 |
Decrease in extracellular water / total body water ratio measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of ECW/TBW (Mean) |
|---|---|
| Placebo | -0.24 |
| Treatment Grup | -2.92 |
decrease in blood pressure compared wit baseline measure (mmhg) (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -5.4 |
| Treatment Grup | -18.1 |
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -10 |
| Treatment Grup | -26.1 |
Increase in the fractional excretion of sodium compared with the baseline measure (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of sodium excreted (Mean) |
|---|---|
| Placebo | -0.348 |
| Treatment Grup | 0.598 |
Measured by bioelectrical impedance analysis, compared to the initial measurement (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.075 |
| Treatment Grup | -4.36 |
161 reviews available for uric acid and Kidney Diseases
| Article | Year |
|---|---|
Amyloid A amyloidosis on medullary sponge kidney in a 28-year-old male with gout: A case report and literature review.
Topics: Adult; Amyloidosis; Gout; Humans; Kidney; Kidney Diseases; Male; Medullary Sponge Kidney; Uric Acid | 2023 |
Therapeutic effects of traditional Chinese medicine on gouty nephropathy: Based on NF-κB signalingpathways.
Topics: Humans; Kidney Diseases; Medicine, Chinese Traditional; NF-kappa B; Signal Transduction; Uric Acid | 2023 |
Update in uric acid, hypertension, and cardiovascular diseases.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Prospective Studies; | 2023 |
The Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation.
Topics: Acute Coronary Syndrome; Humans; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; Risk Factors; U | 2023 |
Clinical Management of Reptile Renal Disease.
Topics: Animals; Gout; Kidney; Kidney Diseases; Reptiles; Uric Acid | 2020 |
Laboratory Evaluation of Renal Function in Birds.
Topics: Animals; Bird Diseases; Birds; Creatinine; Kidney; Kidney Diseases; Nephrology; Urea; Uric Acid; Uri | 2020 |
Fructose Production and Metabolism in the Kidney.
Topics: Animals; Cardiomegaly; Diabetic Nephropathies; Dietary Sugars; Energy Metabolism; Fatty Acids; Fruct | 2020 |
Uric acid and kidney damage in systemic lupus erythematosus.
Topics: Humans; Kidney; Kidney Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis; Uric Acid | 2020 |
Uric Acid Elevation by Favipiravir, an Antiviral Drug.
Topics: Aldehyde Oxidase; Amides; Antiviral Agents; Biotransformation; Coronavirus Infections; COVID-19; Dru | 2020 |
Evolving understanding of cardiovascular protection by SGLT2 inhibitors: focus on renal protection, myocardial effects, uric acid, and magnesium balance.
Topics: Animals; Cardiovascular Diseases; Diabetes Complications; Heart; Humans; Kidney; Kidney Diseases; Ma | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Mechanistic insights into hyperuricemia-associated renal abnormalities with special emphasis on epithelial-to-mesenchymal transition: Pathologic implications and putative pharmacologic targets.
Topics: Animals; Biomarkers; Cytokines; Epithelial-Mesenchymal Transition; Febuxostat; Fibrosis; Gout Suppre | 2020 |
[Asymptomatic Hyperuricemia and Risk Of Cardiovascular and Renal Diseases].
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Disease Progression; Humans; Hyperuricemia; Kidney D | 2020 |
Elevated serum uric acid and risk of cardiovascular or all-cause mortality in maintenance hemodialysis patients: A meta-analysis.
Topics: Adult; Aged; Biomarkers; Cause of Death; Female; Heart Disease Risk Factors; Humans; Hyperuricemia; | 2021 |
Uric Acid and Urate in Urolithiasis: The Innocent Bystander, Instigator, and Perpetrator.
Topics: Animals; Calcium Oxalate; Humans; Kidney Diseases; Uric Acid; Urinary Calculi; Urolithiasis | 2020 |
Uric acid as a cardiorenal mediator: pathogenesis and mechanistic insights.
Topics: Cardiovascular Diseases; Heart Failure; Humans; Hyperuricemia; Kidney Diseases; Uric Acid | 2021 |
Change gout: the need for a new approach.
Topics: Biomarkers; Body Mass Index; Cardiovascular Diseases; Diet Therapy; Disease Progression; Evidence-Ba | 2017 |
The challenge of Mendelian randomization approach.
Topics: Cardiovascular Diseases; Disease Progression; Gout; Humans; Kidney Diseases; Randomized Controlled T | 2017 |
The role of urate-lowering treatment on cardiovascular and renal disease: evidence from CARES, FAST, ALL-HEART, and FEATHER studies.
Topics: Cardiovascular Diseases; Gout; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Kidney Diseas | 2017 |
Predictive Value of Hepatorenal Status in Contrast-Induced Nephropathy Among Patients Receiving Coronary Angiography and/or Intervention: A Systematic Review and Meta-Analysis.
Topics: Biomarkers; Blood Urea Nitrogen; Contrast Media; Coronary Angiography; Glomerular Filtration Rate; H | 2019 |
Uric acid and hypertension: a focused review and practical recommendations.
Topics: Animals; Antioxidants; Blood Pressure; Enzyme Inhibitors; Humans; Hypertension; Hyperuricemia; Kidne | 2019 |
Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?
Topics: Animals; Cardiovascular Diseases; Humans; Hypertension; Kidney; Kidney Diseases; Metabolic Syndrome; | 2013 |
Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?
Topics: Animals; Cardiovascular Diseases; Humans; Hypertension; Kidney; Kidney Diseases; Metabolic Syndrome; | 2013 |
Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?
Topics: Animals; Cardiovascular Diseases; Humans; Hypertension; Kidney; Kidney Diseases; Metabolic Syndrome; | 2013 |
Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal?
Topics: Animals; Cardiovascular Diseases; Humans; Hypertension; Kidney; Kidney Diseases; Metabolic Syndrome; | 2013 |
Serum uric acid and cardio-renal diseases.
Topics: Female; Heart Diseases; Humans; Kidney Diseases; Male; Uric Acid | 2013 |
Uric acid and the kidney.
Topics: Child; Humans; Hyperuricemia; Kidney; Kidney Diseases; Uric Acid | 2014 |
Uric acid, hypertension, and cardiovascular and renal complications.
Topics: Animals; Disease Models, Animal; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Uric Acid; Va | 2013 |
[Renal disease-related clinical examination in a cohort study].
Topics: Cohort Studies; Glomerular Filtration Rate; Humans; Kidney Diseases; Patient Selection; Proteinuria; | 2014 |
Uric Acid as a Marker of Kidney Disease: Review of the Current Literature.
Topics: Animals; Biomarkers; Humans; Kidney Diseases; Uric Acid | 2015 |
Hyperuricemia, urate deposition and the association with hypertension.
Topics: Humans; Hypertension; Hyperuricemia; Kidney; Kidney Diseases; Uric Acid | 2015 |
[Recent Advances in Urinalysis as a Diagnostic Indicator of Renal Diseases].
Topics: Crystallization; Epithelial Cells; Erythrocytes; Fibrin; Humans; Kidney Diseases; Kidney Glomerulus; | 2015 |
[Kidney diseases and metabolic disorders--basics and applications required for general physicians. Topics: IV. Uric acid metabolic disorder (relationship between liyperuricemia and CKD-CVD)].
Topics: Age Factors; Animals; Cardiovascular Diseases; General Practitioners; Humans; Kidney Diseases; Metab | 2015 |
From juvenile hyperuricaemia to dysfunctional uromodulin: an ongoing metamorphosis.
Topics: Adolescent; Chromosomes, Human, Pair 16; DNA Mutational Analysis; Exons; Gout; Hepatocyte Nuclear Fa | 2016 |
[HYPERURICEMIA AND POTENTIAL RISK OF CARDIOVASCULAR AND RENAL DISEASES].
Topics: Aged; Cardiovascular Diseases; Gout; Gout Suppressants; Humans; Hyperuricemia; Kidney Diseases; Male | 2016 |
Hyperuricemia, the kidneys, and the spectrum of associated diseases: a narrative review.
Topics: Gout; Humans; Hyperuricemia; Kidney; Kidney Diseases; Uric Acid | 2016 |
Serum Uric Acid and Progression of Kidney Disease: A Longitudinal Analysis and Mini-Review.
Topics: Cohort Studies; Disease Progression; Humans; Kidney Diseases; Longitudinal Studies; Retrospective St | 2017 |
The role of hyperuricemia and gout in kidney and cardiovascular disease.
Topics: Cardiovascular Diseases; Humans; Hyperuricemia; Incidence; Kidney Diseases; Risk Factors; Uric Acid | 2008 |
[Novelties in the field of progression factors in chronic kidney disease].
Topics: Adult; Amidohydrolases; Animals; Arginine; Carbon; Cardiovascular Diseases; Chronic Disease; Clinica | 2008 |
Between hyperfiltration and impairment: demystifying early renal functional changes in diabetic nephropathy.
Topics: Albuminuria; Cystatins; Cytokines; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Kidne | 2008 |
Uric acid: bystander or culprit in hypertension and progressive renal disease?
Topics: Animals; Disease Models, Animal; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Rats; Uric Ac | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Uric acid and cardiovascular risk.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2008 |
Systemic inflammation, metabolic syndrome and progressive renal disease.
Topics: C-Reactive Protein; Chemokine CCL2; Disease Progression; Fructose; Humans; Inflammation; Kidney Dise | 2009 |
Uric acid: a novel mediator and marker of risk in chronic kidney disease?
Topics: Animals; Biomarkers; Chronic Disease; Clinical Trials as Topic; Disease Models, Animal; Disease Prog | 2009 |
Medical implications of hyperuricemia.
Topics: Animals; Cardiovascular Diseases; Gout; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabo | 2009 |
[Calcium antagonists: current and future applications based on new evidence. The mechanisms on lowering serum uric acid level by calcium channel blockers].
Topics: Anaerobiosis; Calcium Channel Blockers; Cardiovascular Diseases; Depression, Chemical; Gout; Humans; | 2010 |
Uric acid as a factor in the metabolic syndrome.
Topics: Biomarkers; Brazil; Cardiovascular Diseases; Female; Global Health; Humans; Hyperuricemia; Insulin R | 2010 |
Dietary fructose and hypertension.
Topics: Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Fructose; Humans; Hypertensi | 2011 |
Uric acid in hypertension and renal disease: the chicken or the egg?
Topics: Allopurinol; Animals; Blood Pressure; Clinical Trials as Topic; Diet; Disease Progression; Fructose; | 2010 |
The effect of fructose on renal biology and disease.
Topics: Diabetes Mellitus; Diet; Dietary Carbohydrates; Fatty Liver; Female; Fructose; Humans; Hypertension; | 2010 |
Hyperuricaemia and non-alcoholic fatty liver disease (NAFLD): a relationship with implications for vascular risk?
Topics: Cardiovascular Diseases; Chronic Disease; Evidence-Based Medicine; Fatty Liver; Humans; Hyperuricemi | 2011 |
Uric acid as a cardiometabolic risk factor: to be or not to be.
Topics: Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metabolic Syndrome; R | 2011 |
Biomarkers in chronic kidney disease: a review.
Topics: Acetylglucosaminidase; Acute-Phase Proteins; Biomarkers; C-Reactive Protein; Cardiovascular Diseases | 2011 |
Is there anything good in uric acid?
Topics: Age Factors; Brain Diseases; Cardiovascular Diseases; Female; Gout; Humans; Hypertension; Hyperurice | 2011 |
[The correlation between uric acid and the incidence and prognosis of kidney diseases: a systematic review and meta-analysis of cohort studies].
Topics: Humans; Kidney Diseases; Prognosis; Risk Factors; Uric Acid | 2011 |
Cardiovascular and renal effects of hyperuricaemia and gout.
Topics: Biomarkers; Cardiovascular Diseases; Diabetes Complications; Disease Progression; Evidence-Based Med | 2012 |
[Renal affection in gout].
Topics: Creatinine; Gout; Humans; Hyperuricemia; Insulin Resistance; Kidney Diseases; Kidney Glomerulus; Pro | 2012 |
Normal and pathologic concentrations of uremic toxins.
Topics: beta 2-Microglobulin; Chronic Disease; Homocysteine; Humans; Indican; Kidney Diseases; Parathyroid H | 2012 |
Normal and pathologic concentrations of uremic toxins.
Topics: beta 2-Microglobulin; Chronic Disease; Homocysteine; Humans; Indican; Kidney Diseases; Parathyroid H | 2012 |
Normal and pathologic concentrations of uremic toxins.
Topics: beta 2-Microglobulin; Chronic Disease; Homocysteine; Humans; Indican; Kidney Diseases; Parathyroid H | 2012 |
Normal and pathologic concentrations of uremic toxins.
Topics: beta 2-Microglobulin; Chronic Disease; Homocysteine; Humans; Indican; Kidney Diseases; Parathyroid H | 2012 |
Hyperuricaemia: more than just a cause of gout?
Topics: Animals; Biomarkers; Cardiovascular Diseases; Female; Gout; Humans; Hyperuricemia; Inflammation; Kid | 2013 |
Effects of urate-lowering therapy in hyperuricemia on slowing the progression of renal function: a meta-analysis.
Topics: Databases, Factual; Disease Progression; Humans; Hyperuricemia; Kidney Diseases; Randomized Controll | 2013 |
The kidney in hyperuricemia and gout.
Topics: Animals; Gout; Homeostasis; Humans; Hyperuricemia; Kidney; Kidney Diseases; Prognosis; Uric Acid | 2013 |
[Gouty kidney].
Topics: Animals; Diet; Gout; Humans; Hyperuricemia; Kidney Diseases; Sodium Bicarbonate; Tartrates; Uric Aci | 2003 |
[Typing of hypouricemia (uric acid clearance)].
Topics: Allopurinol; Creatinine; Humans; Inappropriate ADH Syndrome; Kidney Diseases; Kidney Tubules; Losart | 2003 |
Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?
Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Female; Humans; Hypertension; Hy | 2003 |
RENAL COMPLICATIONS OF NEOPLASTIC DISEASE.
Topics: Antineoplastic Agents; Bence Jones Protein; Hemorrhage; Humans; Hypercalcemia; Hypokalemia; Hyponatr | 1963 |
[HYPERURICEMIA AND ITS CLINICAL SIGNIFICANCE].
Topics: Blood Chemical Analysis; Carbon Isotopes; Coronary Disease; Humans; Hypertension; Hyperuricemia; Kid | 1963 |
[THE GOUTY KIDNEY--PATHOGENESIS OF HYPERURICEMIA AND PATHOGENIC ROLE OF THE KIDNEY].
Topics: Blood; Gout; Humans; Hyperuricemia; Kidney; Kidney Diseases; Uric Acid | 1963 |
Uric acid: role in cardiovascular disease and effects of losartan.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hyperuri | 2004 |
Novel insights into the pathogenesis of uric acid nephrolithiasis.
Topics: Circadian Rhythm; Glutamine; Humans; Hydrogen-Ion Concentration; Insulin Resistance; Kidney Diseases | 2004 |
Gout: on the brink of novel therapeutic options for an ancient disease.
Topics: Acute Disease; Benzothiadiazines; Diuretics; Female; Gout; Humans; Hypertension; Hyperuricemia; Kidn | 2004 |
[Molybdenum].
Topics: Biomarkers; Coenzymes; Humans; Kidney Diseases; Liver Diseases; Mass Spectrometry; Metalloproteins; | 2004 |
Clinical evidence for the influence of uric acid on hypertension, cardiovascular disease, and kidney disease: a statistical modeling perspective.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Kidney Diseases; Models, St | 2005 |
Uric acid and chronic renal disease: possible implication of hyperuricemia on progression of renal disease.
Topics: Animals; Chronic Disease; Disease Progression; Humans; Hyperuricemia; Kidney Diseases; Risk Factors; | 2005 |
Does asymptomatic hyperuricaemia contribute to the development of renal and cardiovascular disease? An old controversy renewed.
Topics: Animals; Cardiovascular Diseases; Humans; Hyperuricemia; Kidney Diseases; Muscle, Smooth, Vascular; | 2004 |
[Researches on the establishment of chronic nephropathy models and the effect of TCM on these models].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hyperuricemia; Kidney Diseases; Mice; Phytot | 2005 |
Essential hypertension, progressive renal disease, and uric acid: a pathogenetic link?
Topics: Disease Progression; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Kidney Failure, Chronic; | 2005 |
Uric acid--a uremic toxin?
Topics: Animals; Arteriosclerosis; Biomarkers; Enzyme Inhibitors; Humans; Hypertension; Hypertrophy; Hyperur | 2006 |
[Hyperuricemic nephropathy: Pathogenesis, pathophysiology, and therapy].
Topics: DNA-Binding Proteins; Gout; Hepatocyte Nuclear Factor 1-beta; Humans; Hyperuricemia; Kidney Diseases | 2006 |
Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Humans; Kidney Diseases; Uric Acid | 2006 |
Uric acid: its relationship to renal hemodynamics and the renal renin-angiotensin system.
Topics: Humans; Kidney; Kidney Diseases; Renal Circulation; Renin-Angiotensin System; Uric Acid | 2006 |
Analysis of mutations in the urate transporter 1 (URAT1) gene of Japanese patients with hypouricemia in northern Japan and review of the literature.
Topics: Adult; Aged; Female; Humans; Japan; Kidney Diseases; Male; Middle Aged; Mutation; Organic Anion Tran | 2006 |
Serum uric acid as a risk factor for cardiovascular and renal disease: an old controversy revived.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hyperuricemia; Kidney Diseases; Risk Fact | 2006 |
Uric Acid and renal disease.
Topics: Humans; Hyperuricemia; Kidney; Kidney Calculi; Kidney Diseases; Kidney Glomerulus; Models, Biologica | 2006 |
Renal function during normal pregnancy and preeclampsia.
Topics: Angiogenic Proteins; Animals; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidney; Kid | 2007 |
Uric acid, the metabolic syndrome, and renal disease.
Topics: Animals; Disease Models, Animal; Disease Progression; Fructose; Humans; Kidney Diseases; Metabolic S | 2006 |
Role of uric acid in hypertension, renal disease, and metabolic syndrome.
Topics: Biomarkers; Blood Pressure; Fructose; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Metaboli | 2006 |
Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions.
Topics: Biomarkers; Diabetes Insipidus; Female; Humans; Kidney Diseases; Metabolism, Inborn Errors; Polycyst | 2007 |
Tumor lysis syndrome.
Topics: Biomarkers; Humans; Kidney Diseases; Neoplasms; Tumor Lysis Syndrome; Uric Acid | 2007 |
Altered uric acid levels and disease states.
Topics: Animals; Cardiovascular Diseases; Gout; Humans; Hypertension; Hyperuricemia; Inflammation; Kidney Di | 2008 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Fructose; Genetic Predispo | 2007 |
[Membrane transport proteins: update].
Topics: Animals; Carrier Proteins; Humans; Ion Channels; Kidney Diseases; Kidney Tubules; Membrane Proteins; | 2008 |
[Diseases of the exocrine pancreas in infants and children. A review. 1. Organic pancreatic diseases].
Topics: Amino Acid Metabolism, Inborn Errors; Amylases; Child, Preschool; Cholecystokinin; Cystic Fibrosis; | 1980 |
[Kidneys in rheumatic diseases].
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arteritis; Gout; Humans; Immune Complex | 1983 |
[Renal function and pregnancy].
Topics: Adult; Female; Glycosuria, Renal; Humans; Kidney Diseases; Pregnancy; Pregnancy Complications; Renal | 1983 |
[Renal failure caused by non-steroid anti-inflammatory agents].
Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Drug Interactions; Glomerulonephritis; Humans; Hy | 1983 |
Urate nephropathy.
Topics: Allopurinol; Arthritis; Aspirin; Blood Urea Nitrogen; Glomerular Filtration Rate; Gout; Humans; Kidn | 1984 |
[Adverse effect of diuretics: hyperuricosuria].
Topics: Diuretics; Gout; Humans; Kidney; Kidney Diseases; Middle Aged; Uric Acid | 1984 |
Renal manifestations of extrarenal neoplasms.
Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm | 1980 |
[Urate nephropathy].
Topics: Allopurinol; Gout; Humans; Kidney Calculi; Kidney Diseases; Nephritis, Interstitial; Purines; Uric A | 1981 |
[Renal diseases in disturbance of urate metabolism].
Topics: Humans; Kidney; Kidney Diseases; Uric Acid | 1995 |
Renal damage in hypertension.
Topics: Enzymes; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Glomerulus; Nephr | 1995 |
Tumor lysis syndrome: pathogenesis and management.
Topics: Acute Kidney Injury; Humans; Kidney Diseases; Renal Dialysis; Risk Factors; Tumor Lysis Syndrome; Ur | 1995 |
[Kidney diseases caused by hypercalcemia, hyperuricemia, hyperoxaluria and hypokalemia].
Topics: Humans; Hypercalcemia; Hyperoxaluria; Hypokalemia; Kidney; Kidney Diseases; Uric Acid | 1994 |
ABC of rheumatology. Gout, hyperuricaemia, and crystal arthritis.
Topics: Chondrocalcinosis; Gout; Humans; Kidney Diseases; Risk Factors; Uric Acid | 1995 |
[Hyperuricemia].
Topics: Gout; Humans; Kidney Diseases; Uric Acid; Urinary Calculi | 1994 |
Gout, uric acid and purine metabolism in paediatric nephrology.
Topics: Adolescent; Animals; Child; Child, Preschool; Gout; Humans; Infant; Infant, Newborn; Kidney Diseases | 1993 |
[Disorders of uric acid tubular transport leading to hypouricemia].
Topics: Humans; Kidney Diseases; Kidney Tubules; Uric Acid | 1993 |
Rheumatologic manifestations of renal disease.
Topics: Calcium Phosphates; Calcium Pyrophosphate; Chronic Kidney Disease-Mineral and Bone Disorder; Crystal | 1996 |
[Hyperuricemia in hematological disorders].
Topics: Bone Marrow; Bone Marrow Diseases; Hematologic Diseases; Humans; Kidney Diseases; Necrosis; Tumor Ly | 1996 |
[Metabolic disorder of purine nucleotide in patients with renal disease].
Topics: Allopurinol; Arthritis, Gouty; Humans; Kidney Diseases; Purine Nucleotides; Uric Acid | 1996 |
[Pharmacological agents affecting uric acid metabolism].
Topics: Allopurinol; Diuretics; Fructose; Gout; Gout Suppressants; Humans; Inosine; Kidney Diseases; Niacin; | 1996 |
[Renal function in hyperuricemia].
Topics: Humans; Kidney Diseases; Uric Acid | 1997 |
Conservative management of ureteric stones.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colic; Cystine; Humans; Kidney Diseases; Lithotripsy; Remis | 1997 |
Uric acid nephropathy and end-stage renal disease--review of a non-disease.
Topics: Gout; Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Uric Acid | 1997 |
[Familial juvenile gouty nephropathy].
Topics: Adult; Diagnosis, Differential; Family Health; Female; Gout; Humans; Hypertension; Kidney Diseases; | 1998 |
Kelley-Seegmiller syndrome: a case report and review of the literature.
Topics: Adult; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney Diseases; Male; Syndrome; Uric A | 1998 |
Regulation of renal urate excretion: a critical review.
Topics: Algorithms; Biological Transport; Humans; Kidney; Kidney Diseases; Natriuretic Agents; Renal Insuffi | 1998 |
Hyperuricemic nephropathies.
Topics: Humans; Kidney Diseases; Kidney Failure, Chronic; Uric Acid | 1999 |
Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease.
Topics: Cardiovascular Diseases; Gout; Humans; Hypertension; Kidney Diseases; Risk Factors; Uric Acid | 1999 |
Uric acid and cardiovascular disease: a renal-cardiac relationship?
Topics: Cardiovascular Diseases; Humans; Kidney Diseases; Risk Factors; Uric Acid | 2001 |
[Kidney diseases associated with hyperuricemia].
Topics: Female; Humans; Kidney Diseases; Male; Uric Acid | 2001 |
Diagnosing gouty arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Infectious; Arthritis, Rheumat | 2002 |
[Renal markers and predictors, and renal and cardiovascular risk factors].
Topics: Age Factors; Alcohol Drinking; Biomarkers; Blood Pressure; Cardiovascular Diseases; Fatty Acids; Hum | 2002 |
Pathogenesis of hyperuricemia: recent advances.
Topics: Humans; Kidney Diseases; Uric Acid | 2002 |
Implications of disorders of purine metabolism for the kidney and the urinary tract.
Topics: Adenine Phosphoribosyltransferase; Allopurinol; Animals; Calcium; Gout; Humans; Hydrogen-Ion Concent | 1977 |
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human | 1979 |
[Hereditary renal hypouricemia].
Topics: Humans; Kidney Diseases; Uric Acid | 1977 |
Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricaemia.
Topics: Aspirin; Benzbromarone; Benzofurans; Drug Interactions; Fasting; Gout; Humans; Kidney Diseases; Kine | 1977 |
Use of the uricase-inhibited rat as an animal model in toxicology.
Topics: Aggression; Animals; Diet; Disease Models, Animal; Dogs; Embryo, Mammalian; Female; Gout; Humans; Ki | 1978 |
[Uric acid metabolism, specifically the effect of diuretics on the process].
Topics: Allopurinol; Biological Transport; Diuretics; Glomerular Filtration Rate; Gout; Humans; Hypoxanthine | 1979 |
Atherosclerosis and urate metabolism.
Topics: Arteriosclerosis; Coronary Disease; Gout; Humans; Hyperlipidemias; Hyperlipoproteinemia Type IV; Hyp | 1979 |
Renal injury in mu.
Topics: Acute Kidney Injury; Adult; Animals; Glomerular Filtration Rate; Hemodynamics; Humans; Hypokalemia; | 1976 |
Renal involvement in leukemia and lymphoma.
Topics: Amyloidosis; Blood Vessels; Diabetes Insipidus; Humans; Hypercalcemia; Hyponatremia; Kidney; Kidney | 1976 |
[The kidney and uric acid].
Topics: Acute Kidney Injury; Female; Gout; Humans; Hypertension; Kidney; Kidney Calculi; Kidney Diseases; Ki | 1975 |
[Inborn errors of metabolism and their significance in urology and nephrology].
Topics: Acidosis, Renal Tubular; Alkaptonuria; Cystinuria; Diabetes Insipidus; Female; Glycine; Gout; Humans | 1976 |
Uric acid biosynthesis and its disorders.
Topics: Adult; Child, Preschool; Female; Gout; Humans; Immunologic Deficiency Syndromes; Infant; Kidney Calc | 1976 |
Editorial: An evaluation of the pathogenesis of gouty kidney.
Topics: Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney; Kidney Diseases; Kidney Failure, Chron | 1975 |
Renal hypouricemia: classification, tubular defect and clinical consequences.
Topics: Animals; Disease Models, Animal; Humans; Kidney Diseases; Kidney Tubules; Uric Acid | 1992 |
[Physiopathological aspects of secondary hyperuricemia].
Topics: Acute Disease; Coronary Disease; Drug-Related Side Effects and Adverse Reactions; Fructose; Glycogen | 1991 |
[Clinical findings and pathogenesis of renal impairment in hyperuricemia].
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1991 |
Acute uric acid nephropathy.
Topics: Acute Disease; Allopurinol; Chemical Phenomena; Chemistry, Physical; Humans; Kidney; Kidney Diseases | 1990 |
[Significance of blood uric acid determination. Review of the literature].
Topics: Female; Humans; Kidney Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Prognosis; Uric | 1990 |
The pathophysiology and medical treatment of urolithiasis.
Topics: Acidosis, Renal Tubular; Calcium Oxalate; Crystallization; Cystinuria; Humans; Hypercalcemia; Hypero | 1990 |
Urate metabolism and gout--a perspective.
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1988 |
[Current theories on various disorders of uric acid metabolism in the body].
Topics: Adult; Age Factors; Child; Female; Hematologic Diseases; Humans; Infant, Newborn; Kidney; Kidney Dis | 1987 |
Gout.
Topics: Arthritis; Cardiovascular Diseases; Diabetes Complications; Environment; Gout; Humans; Hyperlipidemi | 1987 |
Hyperuricemia and gout.
Topics: Acute Disease; Adult; Allopurinol; Anti-Inflammatory Agents; Arthritis; Arthrography; Calcinosis; Ch | 1986 |
[Hyperuricemia in childhood].
Topics: Anemia, Hemolytic; Child; Down Syndrome; Glycogen Storage Disease; Gout; Humans; Kidney Calculi; Kid | 1973 |
Pre-eclampsia and related complications of pregnancy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Coagulation Disorders; Catecholamines; Diagnosis, Differen | 1970 |
[Renal manifestations of hyperuricemia].
Topics: Acute Kidney Injury; Albuminuria; Cortisone; Gout; Hematuria; Humans; Kidney Calculi; Kidney Disease | 1972 |
Cancer chemotherapy. 3.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Allopurinol; Alopecia; Antimetabolites; Antineoplast | 1972 |
Hyperuricemia in leukemia and lymphoma. II. Treatment.
Topics: Acetazolamide; Allopurinol; Humans; Kidney Diseases; Leukemia; Lymphoma; Renal Dialysis; Uric Acid | 1973 |
Oxalate metabolism. IV.
Topics: Animals; Calcinosis; Calcium; Ethylenes; Glycols; Humans; Kidney Calculi; Kidney Diseases; Metabolic | 1973 |
Renal manifestations of sickle cell disease.
Topics: Acid-Base Equilibrium; Age Factors; Anemia, Sickle Cell; Capillaries; Dilatation; Erythrocytes, Abno | 1974 |
[Urologic and nephrologic laboratory examinations].
Topics: Adult; Diagnosis, Computer-Assisted; Glycosuria; Hemoglobinuria; Humans; Hydrogen-Ion Concentration; | 1974 |
Interaction and interference of some non-steroid anti-inflammatory drugs in man.
Topics: Anti-Inflammatory Agents; Arthritis; Binding Sites; Drug Interactions; Humans; Intestinal Absorption | 1974 |
Liver-kidney interrelation in pregnancy and toxemia.
Topics: Acute Kidney Injury; Ammonia; Erythrocytes; Estrogens; Female; Glomerular Filtration Rate; Glucocort | 1968 |
[The kidney in gout and gout of the kidney].
Topics: Arteriosclerosis Obliterans; Carbohydrate Metabolism; Cerebrovascular Disorders; Diabetes Complicati | 1968 |
Hypertension and renal disease in pregnancy.
Topics: Adrenal Cortex Hormones; Animals; Biopsy; Body Weight; Diet, Sodium-Restricted; Eclampsia; Edema; Fe | 1971 |
Control of uric acid excretion.
Topics: Animals; Dogs; Glycine; Gout; Humans; Kidney; Kidney Diseases; Kidney Tubules; Pyrazinamide; Uric Ac | 1971 |
[Adverse effects and complications of diuretic therapy].
Topics: Acid-Base Equilibrium; Blood Coagulation; Calcium; Carbohydrate Metabolism; Digestive System; Diures | 1971 |
[NPN (BUN): interpretation of the test results].
Topics: Acute Kidney Injury; Amino Acids; Blood Urea Nitrogen; Creatinine; Humans; Kidney Diseases; Nitrogen | 1969 |
Allopurinol. A review.
Topics: Adult; Allopurinol; Child; Drug Hypersensitivity; Drug Interactions; Gout; Humans; Iron; Kidney Dise | 1971 |
Uric acid, gout, and the kidney.
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1966 |
34 trials available for uric acid and Kidney Diseases
| Article | Year |
|---|---|
Febuxostat combined with hydration for the prevention of contrast-induced nephropathy in hyperuricemia patients undergoing percutaneous coronary intervention: A CONSORT-compliant randomized controlled trial.
Topics: Combined Modality Therapy; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Febux | 2022 |
Effect of allopurinol drug use on GFR and proteinuria in patients with renal transplant recipients (ADOPTR study).
Topics: Allopurinol; C-Reactive Protein; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Kidney | 2022 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Febuxostat for Cerebral and CaRdiorenovascular Events PrEvEntion StuDy.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Febuxostat; Female; Gou | 2019 |
[Is there an association of uric acid level with preclinical target organ damage in moderate- and high-risk hypertensive patients?].
Topics: Adult; C-Reactive Protein; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; | 2013 |
Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Biological Availability; Biomarkers; Creatinine | 2016 |
A single dose of rasburicase in elderly patients with hyperuricaemia reduces serum uric acid levels and improves renal function.
Topics: Aged; Aged, 80 and over; Female; Humans; Hyperuricemia; Kidney; Kidney Diseases; Kidney Function Tes | 2009 |
Clinical application of Cordyceps sinensis on immunosuppressive therapy in renal transplantation.
Topics: Adolescent; Adult; Blood Urea Nitrogen; Cordyceps; Creatinine; Female; Graft Survival; Histocompatib | 2009 |
[Clinical study on modified sanmiao powder in treating chronic uric acid nephropathy].
Topics: Adult; Aged; Drugs, Chinese Herbal; Female; Humans; Kidney Diseases; Male; Medicine, Chinese Traditi | 2009 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Dr | 2010 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Dr | 2010 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Dr | 2010 |
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Comorbidity; Dose-Response Relationship, Dr | 2010 |
Obesity-related glomerulopathy: body mass index and proteinuria.
Topics: Adult; Biomarkers; Biopsy; Blood Pressure; Body Mass Index; Caloric Restriction; China; Combined Mod | 2010 |
Effect of allopurinol in chronic kidney disease progression and cardiovascular risk.
Topics: Aged; Allopurinol; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; | 2010 |
Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Creatinine; Dose-Response Relationship, Drug; Drug Moni | 2011 |
[Clinical implication of endothelial dysfunction in patients with essential arterial hypertension and urate dysbolism with renal damage].
Topics: Adult; Albuminuria; Carotid Intima-Media Thickness; Endothelin-1; Endothelium, Vascular; Female; Hum | 2011 |
Comparison of efficacy of the phosphate binders nicotinic acid and sevelamer hydrochloride in hemodialysis patients.
Topics: Adult; Aged; Alkaline Phosphatase; Biomarkers; Calcium; Chelating Agents; Female; Humans; Hyperphosp | 2012 |
Effects of meloxicam on hematologic and plasma biochemical analysis variables and results of histologic examination of tissue specimens of Japanese quail (Coturnix japonica).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Coturnix; Creatine Ki | 2012 |
[Clinical study of treatment on chronic uric acid nephropathy by integrating Western and traditional Chinese medicine].
Topics: Adult; Aged; Allopurinol; Blood Viscosity; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; | 2002 |
Clinical analysis for the acupuncture treatment in 42 cases of gouty renal damage.
Topics: Acupuncture Therapy; Adult; Aged; Arthritis, Gouty; Blood Urea Nitrogen; Creatinine; Female; Gout; H | 2004 |
Introduction of MMF in conjunction with stepwise reduction of calcineurin inhibitor in stable liver transplant patients with renal dysfunction.
Topics: Adult; Aged; Blood Pressure; Calcineurin Inhibitors; Cardiovascular Diseases; Cholesterol; Creatinin | 2005 |
Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level.
Topics: Adult; Aged; Allopurinol; Creatinine; Disease Progression; Enzyme Inhibitors; Female; Follow-Up Stud | 2006 |
Renal outcome after ciclosporin-induced nephrotoxicity.
Topics: Adult; Aged; Blood Glucose; Colorimetry; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomer | 2007 |
Effect of xipamide in oedema of renal disease with varying degrees of renal insufficiency: a comparative trial with frusemide.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Edema; Female; Furosem | 1982 |
Renal handling of urate in healthy man in hyperuricaemia and renal insufficiency: circadian fluctuation, effect of water diuresis and of uricosuric agents.
Topics: Adult; Aged; Circadian Rhythm; Diuresis; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged; | 1980 |
The influence of allopurinol on renal deterioration in familial nepropathy associated with hyperuricemia (FNAH). The Spanish Group for the Study of FNAH.
Topics: Adolescent; Adult; Aged; Allopurinol; Creatinine; Female; Follow-Up Studies; Humans; Hypertension; K | 1994 |
Stimulation of interleukin-1 beta production may be involved in unresponsiveness to erythropoietin therapy.
Topics: Adult; beta 2-Microglobulin; Blood Urea Nitrogen; Cells, Cultured; Erythrocyte Count; Erythrocytes; | 1996 |
Familial renal disease or familial juvenile hyperuricaemic nephropathy?
Topics: Adolescent; Child; Child, Preschool; Creatinine; Diagnosis, Differential; Diet; Female; Humans; Kidn | 1997 |
Safety of tienilic acid.
Topics: Clinical Trials as Topic; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidn | 1979 |
[The effect of allopurinol therapy on kidney processes concomitant with gout].
Topics: Allopurinol; Clinical Trials as Topic; Drug Evaluation; Gout; Humans; Kidney Diseases; Kidney Tubule | 1987 |
Doxycycline in renal insufficiency.
Topics: Clinical Trials as Topic; Creatinine; Doxycycline; Feces; Female; Humans; Kidney Diseases; Male; Mid | 1974 |
[Experimental treatment with fumaric acid monoethylester in psoriasis vulgaris].
Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Eruptio | 1972 |
[Effect of benzbromarone in uricemia and uricosuria].
Topics: Aspirin; Benzofurans; Chlorothiazide; Clinical Trials as Topic; Colchicine; Drug Combinations; Human | 1972 |
[Benziodarone in hyperuricemia due to renal insufficiency].
Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Benzofurans; Clinical Trials as Topic; Gout; Humans; | 1973 |
Capreomycin, ethambutol and rifampicin in apparently incurable pulmonary tuberculosis.
Topics: Adult; Aged; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic | 1969 |
Renal dysfunction associated with methoxyflurane anesthesia. A randomized, prospective clinical evaluation.
Topics: Adult; Aged; Anesthetics; Blood Urea Nitrogen; Body Weight; Creatinine; Halothane; Humans; Hypernatr | 1971 |
767 other studies available for uric acid and Kidney Diseases
| Article | Year |
|---|---|
Urate transport via human PAH transporter hOAT1 and its gene structure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Biological Transport; Blotting, Western; Car | 2003 |
Evaluation of the Role of KIM-1 in Detecting Early Nephrotoxicity in Lead-Exposed Workers.
Topics: Biomarkers; Creatinine; Humans; Kidney; Kidney Diseases; Lead; Renal Insufficiency; Uric Acid | 2021 |
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Berberine; Blood Urea Nitrogen; Ch | 2021 |
Bmk9 and Uricase Nanoparticle Complex for the Treatment of Gouty Arthritis and Uric Acid Nephropathy.
Topics: Arthritis, Gouty; Humans; Kidney Diseases; Nanoparticles; Urate Oxidase; Uric Acid | 2021 |
Impact of the ACE2 activator xanthenone on tacrolimus nephrotoxicity: Modulation of uric acid/ERK/p38 MAPK and Nrf2/SOD3/GCLC signaling pathways.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Calcineurin Inhibitors; Enzyme Activation; | 2022 |
Kidney and plasma metabolomics provide insights into the molecular mechanisms of urate nephropathy in a mouse model of hyperuricemia.
Topics: Animals; Hyperuricemia; Kidney; Kidney Diseases; Metabolomics; Mice; Uric Acid | 2022 |
Serum Uric Acid to Albumin Ratio Can Predict Contrast-Induced Nephropathy in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Topics: Acute Kidney Injury; Albumins; Contrast Media; Creatinine; Humans; Kidney Diseases; Myocardial Infar | 2023 |
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis.
Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Iridoids; Kidney Diseases; Mice; Molecular Docking S | 2022 |
Uric Acid, Genetic Scores and Renal Disease: Merge to Separate?
Topics: Diabetes Mellitus, Type 2; Humans; Kidney; Kidney Diseases; Mendelian Randomization Analysis; Risk F | 2022 |
Study of purine derivatives and their relation to renal disorders in patients with psoriasis.
Topics: Albumins; Case-Control Studies; Creatinine; Diuretics; Humans; Hyperuricemia; Kidney Diseases; Psori | 2023 |
Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis.
Topics: Animals; Fibrosis; Humans; Hyperuricemia; Kidney; Kidney Diseases; Mice; Uric Acid | 2022 |
AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model.
Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Fibrosis; Hyperuricemia; Kidney; Kid | 2022 |
Moderate hyperuricaemia ameliorated kidney damage in a low-renin model of experimental renal insufficiency.
Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Kidney; Kidney Diseases; Nephrectomy; Oxonic Acid; R | 2023 |
Type 3 innate lymphoid cells as an indicator of renal dysfunction and serum uric acid in hyperuricemia.
Topics: Humans; Hyperuricemia; Immunity, Innate; Interleukin-17; Kidney Diseases; Leukocytes, Mononuclear; L | 2023 |
[Effect of granules made by new-medicinal parts of Crocus sativus on hyperuricemia in rats and its mechanism].
Topics: Animals; Creatinine; Crocus; Hyperuricemia; Kidney; Kidney Diseases; Rats; Uric Acid; Xanthine Oxida | 2022 |
Metabolic Dysfunction-Associated Fatty Liver Disease in Newly Diagnosed, Treatment-Naive Hypertensive Patients and Its Association with Cardiorenal Risk Markers.
Topics: Blood Pressure; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypertension; Kidney Diseases; Ma | 2023 |
Qinling liquid ameliorates renal immune inflammatory damage via activating autophagy through AMPK/Stat3 pathway in uric acid nephropathy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammasomes; Kidney Diseases; NLR Family, Pyrin | 2023 |
EVALUATION OF SYMMETRIC DIMETHYLARGININE AS AN ENDOGENOUS MARKER OF RENAL DISEASE IN GREATER FLAMINGOS (
Topics: Animals; Biomarkers; Birds; Dermatitis; Kidney Diseases; Uric Acid | 2023 |
Urinary levels of kidney injury molecule-1 (KIM-1) and interleukin-18 (IL-18) in children and adolescents with hyperuricemia.
Topics: Adolescent; Adult; Biomarkers; Child; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Hyperur | 2023 |
Association between serum uric acid levels of patients with gout and their complications and examination fees: A cross-sectional analysis.
Topics: Cardiovascular Diseases; Cross-Sectional Studies; Female; Gout; Humans; Hyperuricemia; Kidney Diseas | 2023 |
Non-linear association of fasting C-peptide and uric acid levels with renal dysfunction based on restricted cubic spline in patients with type 2 diabetes: A real-world study.
Topics: C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Humans; Kidney Diseases; Uri | 2023 |
Renal herb formula protects against hyperuricemic nephropathy by inhibiting apoptosis and inflammation.
Topics: Animals; Apoptosis; Chlorogenic Acid; Creatinine; Hyperuricemia; Inflammation; Kidney; Kidney Diseas | 2023 |
Estradiol protects female mice from hyperuricemia induced by PCB138 exposure.
Topics: Adult; Animals; Estradiol; Female; Humans; Hyperuricemia; Kidney; Kidney Diseases; Male; Mice; Uric | 2023 |
Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet.
Topics: Animals; Chloroquine; Creatinine; Diet, High-Fat; Fibrosis; Hyperuricemia; Inflammasomes; Kidney; Ki | 2023 |
Kidney damage predictors in children with metabolically healthy and metabolically unhealthy obesity phenotype.
Topics: Adolescent; Adult; Body Mass Index; Child; Humans; Kidney; Kidney Diseases; Metabolic Syndrome; Obes | 2023 |
Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats.
Topics: Amino Acids; Animals; Coffea; Gastrointestinal Microbiome; Hyperuricemia; Kidney; Kidney Diseases; R | 2023 |
Uric acid induced the phenotype transition of vascular endothelial cells
Topics: Allopurinol; Animals; Cells, Cultured; Endothelium, Vascular; Glycocalyx; Gout Suppressants; Hyperur | 2019 |
Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption.
Topics: Animals; Cell Line; Cytokines; Fibrosis; Humans; Hyperuricemia; Inflammasomes; Inflammation; Kidney | 2020 |
The Effect of Urine pH and Urinary Uric Acid Levels on the Development of Contrast Nephropathy.
Topics: Aged; Contrast Media; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Prospective Studies; Uric | 2020 |
Electrochemical analysis of uric acid excretion to the intestinal lumen: Effect of serum uric acid-lowering drugs and 5/6 nephrectomy on intestinal uric acid levels.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cardiovascular Diseases; Disease M | 2019 |
Hyperuricemia is associated with a lower glomerular filtration rate in pediatric sickle cell disease patients.
Topics: Adolescent; Albuminuria; Anemia, Sickle Cell; Blood Transfusion; Child; Cohort Studies; Cross-Sectio | 2020 |
Protective effects of spirulina against hemato-biochemical alterations, nephrotoxicity, and DNA damage upon lead exposition.
Topics: Animals; Creatinine; DNA; DNA Damage; Female; Hematologic Tests; Kidney; Kidney Diseases; Organometa | 2020 |
Ninety-Day Nephrotoxicity Evaluation of 3-MCPD 1-Monooleate and 1-Monostearate Exposures in Male Sprague Dawley Rats Using Proteomic Analysis.
Topics: alpha-Chlorohydrin; Animals; Creatinine; Esters; Humans; Kidney; Kidney Diseases; Male; Proteomics; | 2020 |
Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney.
Topics: Acidosis; Animals; Catecholamine Plasma Membrane Transport Proteins; Kidney Diseases; Male; Mice; Mi | 2020 |
Effects of uric acid dysregulation on the kidney.
Topics: Animals; Biomarkers; Homeostasis; Humans; Hyperuricemia; Kidney; Kidney Diseases; Risk Factors; Uric | 2020 |
Cardiovascular risk assessment after one-year acute ischemic stroke based on uric acid levels and renal dysfunction. A clinical study.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Ischemic Stroke | 2021 |
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Cycloox | 2020 |
Delayed treatment with an autophagy inhibitor 3-MA alleviates the progression of hyperuricemic nephropathy.
Topics: Animals; Autophagy; Disease Models, Animal; Disease Progression; Female; Humans; Hyperuricemia; Kidn | 2020 |
Uric acid is independent and inversely associated to glomerular filtration rate in young adult Brazilian individuals.
Topics: Adult; Age Factors; Biomarkers; Brazil; Cross-Sectional Studies; Female; Glomerular Filtration Rate; | 2020 |
Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Aspartate Amin | 2021 |
Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Genome-Wide Association Study; Glo | 2020 |
Nephrotoxic effects caused by co-exposure to noise and toluene in New Zealand white rabbits: A biochemical and histopathological study.
Topics: Animals; Antioxidants; Catalase; Cholesterol; Creatinine; Female; Glucose; Glutathione Peroxidase; K | 2020 |
Hyperuricemia prevalence in healthy subjects and its relationship with cardiovascular target organ damage.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cross-Sectional Stu | 2021 |
Dendrobium officinalis six nostrum ameliorates urate under-excretion and protects renal dysfunction in lipid emulsion-induced hyperuricemic rats.
Topics: Animals; Anti-Inflammatory Agents; Dendrobium; Disease Models, Animal; Dose-Response Relationship, D | 2020 |
Uric acid to high-density lipoprotein cholesterol ratio predicts cardiovascular mortality in patients on peritoneal dialysis.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Female; Humans; Kidney Diseases; Male; | 2021 |
Uric acid level and kidney function: a cross-sectional study of the Korean national health and nutrition examination survey (2016-2017).
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Humans; Hyperu | 2020 |
Non-alcoholic fatty kidney disease (NAFKD): A novel disease that explains the etiology of hyperuricemia and gout in metabolic syndrome.
Topics: Adult; Female; Gout; Humans; Hyperuricemia; Kidney Diseases; Male; Metabolic Syndrome; Uric Acid | 2021 |
Concomitant administration of HAART aggravates anti-Koch-induced oxidative hepatorenal damage via dysregulation of glutathione and elevation of uric acid production.
Topics: Aminohydrolases; Animals; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Chemical and | 2021 |
Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation.
Topics: Animals; Fibrosis; Hydroxybenzoates; Inflammation; Kidney; Kidney Diseases; Male; NF-kappa B; Nitrof | 2021 |
Effects of fenofibrate therapy on renal function in primary gout patients.
Topics: Creatinine; Drug Monitoring; Electronic Health Records; Female; Fenofibrate; Gout; Humans; Hypolipid | 2021 |
Risk factors for high-dose methotrexate-induced nephrotoxicity.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; Hematologic Neoplasms; Humans; Kid | 2021 |
Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling.
Topics: Administration, Oral; Animals; Fibrosis; Flavonols; Gene Expression Regulation; Hyperuricemia; Inter | 2021 |
Network pharmacology and molecular docking analysis on molecular targets: Mechanisms of baicalin and baicalein against hyperuricemic nephropathy.
Topics: Allopurinol; Animals; Blood Urea Nitrogen; Flavanones; Flavonoids; Kidney Diseases; Liver; Mice; Mol | 2021 |
Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway.
Topics: Animals; Apigenin; beta Catenin; Creatinine; Dose-Response Relationship, Drug; Fibrosis; Glucose Tra | 2021 |
The Rho kinase signaling pathway participates in tubular mitochondrial oxidative injury and apoptosis in uric acid nephropathy.
Topics: Apoptosis; Cell Line; Humans; Kidney Diseases; Mitochondria; Oxidative Stress; rho-Associated Kinase | 2021 |
The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Apoptosis; Blood Urea Nitrogen; Creatinine; Dose-Response | 2021 |
Comparative study of a novel selective urate reabsorption inhibitor "dotinurad" among patient groups with different stages of renal dysfunction.
Topics: Adult; Aged; Benzothiazoles; Biomarkers; Clinical Trials as Topic; Female; Glomerular Filtration Rat | 2021 |
Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model.
Topics: Animals; Berberine; Disease Models, Animal; Hyperuricemia; Kidney; Kidney Diseases; Male; Mice; Mole | 2021 |
Betaine attenuates sodium arsenite-induced renal dysfunction in rats.
Topics: Animals; Antioxidants; Arsenic; Arsenites; Betaine; Creatinine; Glutathione; Hydroxyproline; Kidney | 2022 |
microRNA-199a downregulation alleviates hyperuricemic nephropathy
Topics: Animals; beta Catenin; Down-Regulation; Fibrosis; Hyperuricemia; Kidney Diseases; MicroRNAs; PPAR ga | 2022 |
Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney.
Topics: Animals; Caspase 1; Epithelial-Mesenchymal Transition; Fibrosis; Inflammasomes; Inflammation; Kidney | 2017 |
Short Communication: Evaluation of nephrotoxicity by aspirin-clopidogrel combination therapy in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aspirin; Biomarkers; Blood Urea Nitrogen; Clopidogrel; Creatinine; Drug The | 2016 |
Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats.
Topics: Animals; Anion Transport Proteins; Cytokines; Disease Models, Animal; Disease Progression; Fibroblas | 2017 |
Prevalence and complications of hypouricemia in a general population: A large-scale cross-sectional study in Japan.
Topics: Adult; Cross-Sectional Studies; Female; Hospitals; Humans; Japan; Kidney Diseases; Male; Middle Aged | 2017 |
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Topics: Animals; Collagen; Disease Progression; Down-Regulation; Drugs, Chinese Herbal; Extracellular Matrix | 2017 |
Performance of AHEAD Score in an Asian Cohort of Acute Heart Failure With Either Preserved or Reduced Left Ventricular Systolic Function.
Topics: Acute Disease; Aged; Aged, 80 and over; Asian People; Atrial Fibrillation; Biomarkers; Cardiovascula | 2017 |
Reply to: Uric Acid and Contrast-Induced Nephropathy: Diagnostic Marker, Therapeutic Target, or Innocent Bystander?
Topics: Humans; Kidney Diseases; Uric Acid | 2017 |
The Role of Free Radical Oxidation in the Development of Experimental Urate Nephropathy.
Topics: Animals; Free Radicals; Kidney Diseases; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wi | 2017 |
[The uric acid cardio-nephropathy].
Topics: Biomarkers; Heart Diseases; Humans; Hyperuricemia; Kidney Diseases; Risk Factors; Uric Acid | 2017 |
[Strengthen and standardize the diagnosis and treatment of hyperuricemia in kidney diseases].
Topics: Humans; Hyperuricemia; Kidney; Kidney Diseases; Uric Acid | 2017 |
Detection of Urate Crystals in Kidney Tissue.
Topics: Disease Progression; Humans; Kidney; Kidney Diseases; Uric Acid | 2017 |
The impact of gallic acid on the methotrexate-induced kidney damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Creatin | 2017 |
Emodinol ameliorates urate nephropathy by regulating renal organic ion transporters and inhibiting immune inflammatory responses in rats.
Topics: Animals; Blood Urea Nitrogen; Hyperuricemia; Inflammasomes; Inflammation; Interleukin-1beta; Kidney; | 2017 |
Sex-related relationships between uric acid and target organ damage in hypertension.
Topics: Adult; Aged; Carotid Artery Diseases; Carotid Intima-Media Thickness; Correlation of Data; Cross-Sec | 2018 |
Effects of Polygonum cuspidatum on AMPK-FOXO3α Signaling Pathway in Rat Model of Uric Acid-Induced Renal Damage.
Topics: AMP-Activated Protein Kinases; Animals; Chemokine CCL2; Disease Models, Animal; Fallopia japonica; F | 2019 |
Weicao capsule ameliorates renal injury through increasing autophagy and NLRP3 degradation in UAN rats.
Topics: Allopurinol; Animals; Autophagy; Cell Line; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; | 2018 |
Self-powered implantable electronic-skin for in situ analysis of urea/uric-acid in body fluids and the potential applications in real-time kidney-disease diagnosis.
Topics: Animals; Biosensing Techniques; Body Fluids; Electric Power Supplies; Humans; Implants, Experimental | 2018 |
The Pathophysiology of Uric Acid on Renal Diseases.
Topics: Animals; Disease Models, Animal; Hemodynamics; Humans; Hypertension; Hyperuricemia; Kidney Diseases; | 2018 |
Hypouricemia and hyperuricosuria in a pubescent girl: Questions.
Topics: Child; Female; Humans; Kidney Diseases; Uric Acid | 2018 |
Risk Factors of Renal Involvement Based on Different Manifestations in Patients with Ankylosing Spondylitis.
Topics: Female; Hematuria; Humans; Immunoglobulin A; Kidney Diseases; Logistic Models; Male; Risk Factors; S | 2018 |
Monosodium urate crystals induced ICAM-1 expression and cell-cell adhesion in renal mesangial cells: Implications for the pathogenesis of gouty nephropathy.
Topics: Cell Adhesion; Cell Line; Gout; Humans; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; | 2020 |
Experimental heat stress nephropathy and liver injury are improved by allopurinol.
Topics: Allopurinol; Animals; Collagen; Disease Models, Animal; Enzyme Inhibitors; Heat Stress Disorders; Ho | 2018 |
Diosmin and crocin alleviate nephropathy in metabolic syndrome rat model: Effect on oxidative stress and low grade inflammation.
Topics: Animals; Blood Glucose; Blood Pressure; Carotenoids; Diosmin; Drug Therapy, Combination; Glycation E | 2018 |
Temporal trends in hyperuricaemia in the Irish health system from 2006-2014: A cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Hyperuricemia; Ireland; | 2018 |
Comorbidity in gout at the time of first diagnosis: sex differences that may have implications for dosing of urate lowering therapy.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Comorbidity; Dose-Response Relationship, Drug; Early | 2018 |
Genetic Background of a Juvenile Onset Gout Patient.
Topics: Adult; Genetic Background; Gout; Humans; Hyperuricemia; Kidney Diseases; Male; Uric Acid; Young Adul | 2018 |
Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Clinical Trials, Phase III as T | 2019 |
Potential protective effects of the edible alga Arthrospira platensis against lead-induced oxidative stress, anemia, kidney injury, and histopathological changes in adult rats.
Topics: Anemia; Animals; Biomarkers; Catalase; Creatinine; Glutathione Peroxidase; Kidney; Kidney Diseases; | 2019 |
Effect of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on cisplatin-induced nephrotoxicity in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Canagliflozin; Catalase; Cis | 2019 |
Tubular dysfunction in extremely low birth weight survivors.
Topics: Adolescent; Adult; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Female; Glomerular | 2019 |
CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy.
Topics: Animals; Blood Urea Nitrogen; Chemokine CXCL1; Disease Models, Animal; Humans; Interleukin-8; Kidney | 2018 |
Sodium-glucose co-transporter 2 inhibitors and serum uric acid.
Topics: Glucose; Humans; Kidney Diseases; Sodium; Sodium-Glucose Transporter 2 Inhibitors; Uric Acid | 2019 |
Mechanistic Insights of Soluble Uric Acid-related Kidney Disease.
Topics: Humans; Hyperuricemia; Kidney; Kidney Diseases; Risk Factors; Uric Acid | 2020 |
Effects of quercetin and arginine on the nephrotoxicity and lipid peroxidation induced by gold nanoparticles in vivo.
Topics: Animals; Antioxidants; Arginine; Blood Urea Nitrogen; Creatinine; Glutathione; Gold; Kidney; Kidney | 2018 |
Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy.
Topics: Animals; Blueberry Plants; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Fibronectins; | 2019 |
Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia.
Topics: Animals; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Fibroblasts; Fibrosis; Histones; Hype | 2019 |
The flavonoid-rich fraction from rhizomes of Smilax glabra Roxb. ameliorates renal oxidative stress and inflammation in uric acid nephropathy rats through promoting uric acid excretion.
Topics: Animals; Flavonoids; Inflammation; Inflammation Mediators; Kidney Diseases; Male; Oxidative Stress; | 2019 |
Association of serum uric acid levels with the incident of kidney disease and rapid eGFR decline in Chinese individuals with eGFR > 60 mL/min/1.73 m
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; China; Disease Progression; Female; Glomerular Filtratio | 2019 |
Associations Between Serum Uric Acid Concentrations and Cardiometabolic Risk and Renal Injury in Obese and Overweight Children
Topics: Adolescent; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Female; Follow-Up Studies; | 2019 |
Relationship between serum uric acid and clustering of cardiovascular disease risk factors and renal disorders among Shanghai population: a multicentre and cross-sectional study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; China; Cluster Analysis; Cross- | 2019 |
Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
.
Topics: Aged; Aged, 80 and over; Calcium; Diuresis; Diuretics; Female; Fluid Therapy; Humans; Hyponatremia; | 2019 |
HPLC Analysis and In Vivo Renoprotective Evaluation of Hydroalcoholic Extract of Cucumis melo Seeds in Gentamicin-Induced Renal Damage.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Chromatography, High Pressure Liquid; Crea | 2019 |
Relative and attributable diabetes risk associated with hyperuricemia in US veterans with gout.
Topics: Aged; Cohort Studies; Comorbidity; Diabetes Mellitus, Type 2; Female; Gout; Humans; Hyperuricemia; K | 2013 |
Serum urate and incidence of kidney disease among veterans with gout.
Topics: Aged; Body Mass Index; Comorbidity; Gout; Humans; Hyperuricemia; Incidence; Kidney Diseases; Male; M | 2013 |
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
Topics: Age of Onset; Alleles; Animals; Body Weight; Cystatins; Disease Models, Animal; Disease Progression; | 2013 |
Survival impact of serum uric acid levels in children and adolescents.
Topics: Adolescent; Cardiovascular Diseases; Cause of Death; Child; Female; Humans; Hyperuricemia; Kidney Di | 2013 |
Factors related with the progression of chronic kidney disease.
Topics: Aged; Anemia; Calcium; Chronic Disease; Chronic Kidney Disease-Mineral and Bone Disorder; Diabetic N | 2013 |
Relation of uric acid and contrast-induced nephropathy in patients undergoing primary percutaneous coronary intervention in the ED.
Topics: Age Factors; Contrast Media; Creatinine; Emergency Service, Hospital; Female; Glomerular Filtration | 2014 |
Protective effect of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats induced by yeast and potassium oxonate.
Topics: Animals; Base Sequence; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; DNA Primers; Hypert | 2014 |
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload.
Topics: Alleles; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; | 2014 |
High prevalence and risk factors for kidney dysfunction in patients with atherosclerotic cardio-cerebrovascular disease.
Topics: Age Factors; Aged; Aged, 80 and over; Atherosclerosis; Cerebrovascular Disorders; China; Coronary Di | 2014 |
Serum uric acid and the risk of mortality during 23 years follow-up in the Scottish Heart Health Extended Cohort Study.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Diabetes Mellitus; Dyslipidemias; Female; Foll | 2014 |
Cigarette smoking and hyperglycemia increase renal response to low levels of cadmium in welders: cystatin C as a sensitive marker.
Topics: Air Pollutants, Occupational; Analysis of Variance; Biomarkers; Cadmium; Creatinine; Cystatin C; Dia | 2014 |
A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats.
Topics: Animals; Biomarkers; Creatinine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glycyrrhiz | 2014 |
Sodium selenite and vitamin E in preventing mercuric chloride induced renal toxicity in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Creatinine; Glutathione Peroxidase; Kidney; Ki | 2014 |
Increased levels of serum γ-glutamyltransferase and uric acid on metabolic, hepatic and kidney parameters in subjects at high altitudes.
Topics: Adult; Aged; Altitude; Biomarkers; Dyslipidemias; Female; gamma-Glutamyltransferase; Hemoglobins; Hu | 2015 |
[Effect of compound qingqin liquid on the expression of toll-like receptor in the renal tissue of rats with urate nephropathy].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Kidney Diseases; Male; Rats; Rats, S | 2014 |
[Effect of compound qingqin liquid on the expression levels of ang II and COX-2 mRNA transcription and protein expression in the renal tissue of uric acid nephropathy rats: an experimental study].
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Ki | 2014 |
Osteonecrosis with renal damage in HIV patients undergoing HAART.
Topics: Antiretroviral Therapy, Highly Active; Arthritis, Rheumatoid; Creatinine; Cystatin C; HIV Infections | 2014 |
Cardiovascular-renal changes after kidney donation: one-year follow-up study.
Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Female; Follow-Up Studies; Glomerular Fi | 2015 |
Uric acid levels and the risk of Contrast Induced Nephropathy in patients undergoing coronary angiography or PCI.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Choleste | 2015 |
Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Allopurinol; Cardiovascular Diseases; Chronic Disease; Comorbi | 2014 |
Sex differences in renal and metabolic responses to a high-fructose diet in mice.
Topics: Animals; Aquaporin 2; Diuresis; Electrolytes; Female; Fructose; Glucose Transport Proteins, Facilita | 2015 |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidne | 2014 |
Uric acid and mild renal impairment in patients with ST-elevation myocardial infarction.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Glomerular Filtration Rate; Humans; Hyperuricemia; Kidn | 2015 |
Smaller caliber renal arteries are a novel feature of uromodulin-associated kidney disease.
Topics: Adolescent; Adult; Aged; Angiography; Child; Chronic Disease; Female; Genotype; Glomerular Filtratio | 2015 |
Synergistic protective effects of ceftriaxone and ascorbic acid against subacute deltamethrin-induced nephrotoxicity in rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Ascorbic Acid; Ceftriaxone; Creatinine; Disease Models, | 2015 |
Anti-hyperuricemic and nephroprotective effects of rhein in hyperuricemic mice.
Topics: Animals; Anthraquinones; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Her | 2015 |
Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy.
Topics: Allopurinol; Animals; Anion Transport Proteins; Cell Line; Disease Models, Animal; Endocytosis; Intr | 2015 |
EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.
Topics: Animals; Chemokines; Cytokines; Disease Progression; ErbB Receptors; Fibroblasts; Fibrosis; Gefitini | 2015 |
Effects of losartan on expression of monocyte chemoattractant protein-1 (MCP-1) in hyperuricemic nephropathy rats.
Topics: Animals; Chemokine CCL2; Dose-Response Relationship, Drug; Hyperuricemia; Kidney; Kidney Diseases; L | 2015 |
Hyperuricaemia is associated with renal damage independently of hypertension and intrarenal renin-angiotensin system activation, as well as their circadian rhythms.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Angiotensinogen; Biomarkers; Blood Pressure; Circadian | 2015 |
Hyperuricemia and tissue monourate deposits: prospective therapeutic considerations.
Topics: Asymptomatic Diseases; Cardiovascular Diseases; Cartilage; Gout; Humans; Hyperuricemia; Kidney Disea | 2015 |
[Protective effect of curcumin derivative B06 on kidney of type 2 diabetic rats].
Topics: Animals; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Curcumin; Diabetes Mellitus, Experimenta | 2015 |
[The endogenous intoxication in pathogenesis of nephropathies].
Topics: Humans; Kidney; Kidney Diseases; Oxidative Stress; Uric Acid | 2015 |
[Disturbance of uric acid metabolism].
Topics: Gout; Humans; Hyperuricemia; Kidney Diseases; Metabolism, Inborn Errors; Nucleic Acids; Renal Tubula | 2015 |
Modified halloysite nanotubes and the alleviation of kidney damage induced by dietary zearalenone in swine.
Topics: Aluminum Silicates; Animals; Animals, Newborn; Blood Urea Nitrogen; Clay; Creatinine; Cytokines; Die | 2015 |
Renal impairment in different phenotypes of Wilson disease.
Topics: Adolescent; Blood Urea Nitrogen; Creatinine; Female; Hepatolenticular Degeneration; Humans; Kidney D | 2015 |
Ulcerated tophaceous gout.
Topics: Anemia; Anti-Bacterial Agents; Calculi; Clostridium Infections; Gout; Honey; Humans; Hyperuricemia; | 2015 |
Effect of Sodium Selenite on Pathological Changes and Renal Functions in Broilers Fed a Diet Containing Aflatoxin B₁.
Topics: Aflatoxin B1; Animals; Body Weight; Chickens; Creatinine; Dietary Supplements; Kidney; Kidney Diseas | 2015 |
Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Body Mass Index; Comorbidity; Female; Gene Frequen | 2016 |
Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.
Topics: Animals; Apoptosis; Calcium Oxalate; Calcium Pyrophosphate; Humans; Kidney Diseases; Mice; Mice, Inb | 2016 |
Influence of changes in serum uric acid levels on renal function in elderly patients with hypertension: a retrospective cohort study with 3.5-year follow-up.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Cohort Studies; Female; Follow-Up Studies; Glom | 2016 |
Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy.
Topics: Animals; Cell Membrane; Crystallization; Disease Models, Animal; Endocytosis; Folic Acid; Kidney Dis | 2016 |
Urate crystals deposition in the feet of overweight juveniles and those with symptomatic hyperuricemia: a dual-energy CT study.
Topics: Adolescent; Biomarkers; Child; Female; Follow-Up Studies; Gout; Humans; Hyperuricemia; Kidney Diseas | 2016 |
Uric Acid is a Useful Tool to Predict Contrast-Induced Nephropathy.
Topics: Aged; Contrast Media; Creatinine; Female; Hospitalization; Humans; Kidney Diseases; Male; Middle Age | 2017 |
Uric acid and cardiovascular-renal disease risk. Insights from a human model opposite to hypertension.
Topics: Adolescent; Adult; Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Female; Humans; Hypert | 2016 |
Ameliorative effect of naringin in acetaminophen-induced hepatic and renal toxicity in laboratory rats: role of FXR and KIM-1.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; | 2016 |
Rehydration with soft drink-like beverages exacerbates dehydration and worsens dehydration-associated renal injury.
Topics: Animals; Blood Pressure; Carbonated Beverages; Dehydration; Fluid Therapy; Fructose; Glycopeptides; | 2016 |
Uric Acid and Contrast-Induced Nephropathy: Diagnostic Marker, Therapeutic Target, or Innocent Bystander?
Topics: Humans; Kidney Diseases; Uric Acid | 2017 |
Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?
Topics: Adult; Aged; Aged, 80 and over; Female; Fructose; Humans; Hyponatremia; Kidney Diseases; Kidney Tubu | 2016 |
The Association Between Adiponectin, Serum Uric Acid and Urinary Markers of Renal Damage in the General Population: Cross-Sectional Data from the Tromsø Study.
Topics: Adiponectin; Albuminuria; Biomarkers; Cross-Sectional Studies; Female; Humans; Kidney Diseases; Male | 2016 |
Accumulation of methylglyoxal and d-lactate in Pb-induced nephrotoxicity in rats.
Topics: Animals; Biomarkers; Body Weight; Creatinine; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Lact | 2017 |
Familial juvenile hyperuricemic nephropathy as rare cause of dialysis-dependent chronic kidney disease-a series of cases in two families.
Topics: Adolescent; Adult; Child; Child, Preschool; DNA Mutational Analysis; Female; Gout; Humans; Hyperuric | 2016 |
Protodioscin ameliorates fructose-induced renal injury via inhibition of the mitogen activated protein kinase pathway.
Topics: Animals; Diet; Dietary Carbohydrates; Dioscorea; Diosgenin; Extracellular Signal-Regulated MAP Kinas | 2016 |
Nephroprotective efficacy of ceftriaxone against cisplatin-induced subchronic renal fibrosis in rats.
Topics: Actins; Animals; Biomarkers; Bromodeoxyuridine; Ceftriaxone; Cell Proliferation; Cisplatin; Creatini | 2017 |
AJKD Atlas of Renal Pathology: Gouty Nephropathy.
Topics: Diagnosis, Differential; Gout; Humans; Kidney; Kidney Diseases; Microscopy; Uric Acid | 2017 |
The burden of major adverse cardiac events in patients with coronary artery disease.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Area Under Curve; Chi-Square Distribution; | 2017 |
Soluble Uric Acid Activates the NLRP3 Inflammasome.
Topics: Animals; Caspase 1; Cells, Cultured; Disease Models, Animal; Fibrosis; Inflammasomes; Interleukin-1b | 2017 |
Serum uric acid levels contribute to new renal damage in systemic lupus erythematosus patients.
Topics: Adult; Disease Progression; Female; Humans; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Lupus Er | 2017 |
Congolese children with sickle cell trait may exhibit glomerular hyperfiltration: A case control study.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Creatine; Democratic Republic of the Cong | 2017 |
The relationship between liver-kidney impairment and viral load after nephropathogenic infectious bronchitis virus infection in embryonic chickens.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Chick Embryo; Coron | 2017 |
Effect of Rhizoma Polygoni Cuspidati and Ramulus Cinnamomi compatibility on uric acid metabolism and urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in rats with hyperuricemia.
Topics: Animals; Blood Urea Nitrogen; Cell Adhesion Molecules; Creatinine; Drugs, Chinese Herbal; Hyperurice | 2017 |
Increased childhood BMI is associated with young adult serum uric acid levels: a linkage study from Japan.
Topics: Adult; Anthropometry; Body Mass Index; Child; Coronary Disease; Female; Humans; Hypertension; Japan; | 2017 |
Evaluation of the Relationship Between Serum Uric Acid Levels and Cardiovascular Events in Patients With Gout: A Retrospective Analysis Using Electronic Medical Record Data.
Topics: Adult; Electronic Health Records; Female; Gout; Heart Failure; Humans; Kidney Diseases; Male; Middle | 2017 |
Does the serum uric acid level have any relation to arterial stiffness or blood pressure in adults with congenital renal agenesis and/or hypoplasia?
Topics: Adult; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Congenital Abnormaliti | 2017 |
[Acute and chronic renal insufficiency. Diagnostics and practical implications].
Topics: Acute Kidney Injury; Creatinine; Diagnosis, Differential; Humans; Kidney Diseases; Kidney Failure, C | 2008 |
A novel mutation of SLC22A12 gene causing primary renal hypouricemia in a patient with metabolic syndrome.
Topics: Adult; Aged; Creatinine; Diabetes Mellitus, Type 2; DNA Mutational Analysis; Family; Female; Humans; | 2008 |
Elevated uric acid increases the risk for kidney disease.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cholesterol, HDL; Female; Glomerular | 2008 |
Uric acid levels increase risk for new-onset kidney disease.
Topics: Antioxidants; Disease Progression; Humans; Kidney Diseases; Nephrology; Research Design; Risk; Treat | 2008 |
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Angiotensins; Animals; Cells, Cultured; Disease Models | 2008 |
Prevalence of hypouricaemia and SLC22A12 mutations in healthy Korean subjects.
Topics: Adult; Asian People; Blood Pressure; Creatinine; Female; Gene Frequency; Genetic Predisposition to D | 2008 |
Urinary transforming growth factor beta1 in children and adolescents with congenital solitary kidney.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Female; Glomerular Filtration Rate; Humans; Infant; | 2009 |
Naringenin protects against cadmium-induced oxidative renal dysfunction in rats.
Topics: Animals; Antioxidants; Cadmium Chloride; Creatinine; Flavanones; Glutathione; Kidney; Kidney Disease | 2009 |
Uric acid and cardiovascular risk.
Topics: Allopurinol; Antimetabolites; Biomarkers; Cardiovascular Diseases; Humans; Hyperuricemia; Kidney Dis | 2009 |
Association of uric acid with inflammation, progressive renal allograft dysfunction and post-transplant cardiovascular risk.
Topics: Adult; C-Reactive Protein; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Humans; Hype | 2009 |
Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Dyslipidemias; Epidemiologic Methods; Fe | 2010 |
Uric acid as a marker for renal dysfunction in hypertensive women on diuretic and nondiuretic therapy.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chronic Disease; Creatinine; Cross-Se | 2009 |
Children's toxicology from bench to bed--Drug-induced renal injury (2): Nephrotoxicity induced by cisplatin and ifosfamide in children.
Topics: Adolescent; Antineoplastic Agents; Cell Death; Child; Child, Preschool; Cisplatin; Dose-Response Rel | 2009 |
Does glomerular hyperfiltration in pregnancy damage the kidney in women with more parities?
Topics: Adult; Aged; Analysis of Variance; Body Mass Index; Cohort Studies; Confidence Intervals; Creatinine | 2009 |
Evaluation of the proximal tubular function in individuals with primary renal hypouricemia: an NMR-based metabonomic study.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Tubules, Proximal; Male; Metabolomics; Middle Aged; N | 2009 |
Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Humans; Kidney D | 2009 |
Fibrinogen, hematocrit, platelets in mild kidney dysfunction and the role of uric acid: an Italian male population study.
Topics: Adult; Aged; Blood Viscosity; Fibrinogen; Glomerular Filtration Rate; Hematocrit; Hemostasis; Humans | 2011 |
Metabolic factors associated with urinary calculi in children.
Topics: Adolescent; Calcium; Child; Child, Preschool; Citric Acid; Cystinuria; Female; Humans; Hypercalciuri | 2010 |
Exposure to volatile organic compounds and kidney dysfunction in thin film transistor liquid crystal display (TFT-LCD) workers.
Topics: Adult; Age Factors; Creatinine; Cross-Sectional Studies; Electronics; Female; Humans; Kidney Disease | 2010 |
High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up.
Topics: Adolescent; Adult; Albuminuria; Creatinine; Cystatin C; Diabetes Mellitus, Type 1; Disease Progressi | 2010 |
Very low-grade albuminuria reflects susceptibility to chronic kidney disease in combination with cardiovascular risk factors.
Topics: Adult; Albuminuria; Cardiovascular Diseases; Chronic Disease; Cohort Studies; Creatinine; Cross-Sect | 2010 |
[Association between serum uric acid and early kidney damage in middle-aged and elderly].
Topics: Aged; China; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Male; | 2010 |
Relationship between serum uric acid levels with chronic kidney disease in a Southeast Asian population.
Topics: Adult; Asian People; Biomarkers; Chi-Square Distribution; Chronic Disease; Comorbidity; Cross-Sectio | 2010 |
The relationship between serum uric acid and chronic kidney disease among Appalachian adults.
Topics: Adult; Appalachian Region; Body Mass Index; Cardiovascular Diseases; Chronic Disease; Female; Glomer | 2010 |
Pro-inflammatory and oxidative effects of noncrystalline uric acid in human mesangial cells: contribution to hyperuricemic glomerular damage.
Topics: Cell Line, Transformed; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Respons | 2011 |
Association of uric acid with risk factors for chronic kidney disease and metabolic syndrome in patients with essential hypertension.
Topics: Adult; Age Factors; Aged; Biomarkers; Blood Glucose; Blood Pressure; Chronic Disease; Creatinine; Fe | 2010 |
Serum uric acid predicts progression of subclinical coronary atherosclerosis in individuals without renal disease.
Topics: Adult; Coronary Artery Disease; Disease Progression; Female; Humans; Kidney Diseases; Male; Middle A | 2010 |
A prediction model for the risk of incident chronic kidney disease.
Topics: Adult; Age Factors; Aged; Asian People; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; | 2010 |
Dietary intake and the risk of hyperuricemia, gout and chronic kidney disease in elderly Taiwanese men.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Comorbidity; Diet; Feeding Behavior; Glomerular Filt | 2011 |
Hyperuricaemia and accelerated reduction in renal function.
Topics: Adult; Aged; Chronic Disease; Cohort Studies; Creatinine; Disease Progression; Female; Follow-Up Stu | 2011 |
Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21.
Topics: Chromosomes, Human, Pair 2; Female; Genetic Heterogeneity; Genetic Linkage; Genetic Loci; Genetic Pr | 2011 |
A case of familial juvenile hyperuricemic nephropathy with novel uromodulin gene mutation, a novel heterozygous missense mutation in Korea.
Topics: Adolescent; Asian People; Chromosomes, Human, Pair 16; Chronic Disease; DNA Mutational Analysis; Gen | 2010 |
Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice.
Topics: Acetylglucosaminidase; Albuminuria; Animals; beta 2-Microglobulin; Blood Urea Nitrogen; Carrier Prot | 2011 |
Association of renal manifestations with serum uric acid in Korean adults with normal uric acid levels.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Cholesterol; Female; Glo | 2010 |
Use of amino-terminal pro-B type natriuretic peptide as the parameter for long-term monitoring of water overload in patient with chronic kidney diseases.
Topics: Biomarkers; Body Water; Chronic Disease; Creatinine; Female; Humans; Kidney Diseases; Male; Middle A | 2011 |
Treatment of gout.
Topics: Aged; Allopurinol; Australia; Colchicine; Dose-Response Relationship, Drug; Drug Therapy, Combinatio | 2011 |
Management of asymptomatic hyperuricaemia in patients with chronic kidney disease by Japanese nephrologists: a questionnaire survey.
Topics: Chronic Disease; Glomerular Filtration Rate; Humans; Hyperuricemia; Japan; Kidney Diseases; Surveys | 2011 |
Uric acid and pentraxin-3 levels are independently associated with coronary artery disease risk in patients with stage 2 and 3 kidney disease.
Topics: Aged; C-Reactive Protein; Coronary Angiography; Coronary Artery Disease; Disease Progression; Female | 2011 |
Uric acid as a link between renal dysfunction and both pro-inflammatory and prothrombotic state in patients with metabolic syndrome and coronary artery disease.
Topics: Aged; Biomarkers; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Hyperuricemia; Inflamm | 2011 |
[Restriction of fructose intake can prevent hyperuricemia, glomerular filtration and cardiovascular diseases].
Topics: Coronary Artery Disease; Female; Humans; Kidney Diseases; Male; Metabolic Syndrome; Uric Acid | 2011 |
Renal tubular dysfunction in pediatric patients with beta-thalassemia major.
Topics: Acetylglucosaminidase; Adolescent; beta-Thalassemia; Child; Cross-Sectional Studies; Female; Ferriti | 2011 |
Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats.
Topics: Animals; Blood Urea Nitrogen; Connective Tissue Growth Factor; Creatinine; Dinoprostone; Disease Mod | 2011 |
Evaluation of phytoconstituents and anti-nephrotoxic and antioxidant activities of Monochoria vaginalis.
Topics: Acetaminophen; Animals; Antioxidants; Creatine; Disease Models, Animal; Ethanol; Kidney Diseases; Ma | 2011 |
Uric acid levels and all-cause and cardiovascular mortality in the hemodialysis population.
Topics: Adult; Aged; Australia; Biomarkers; Canada; Cardiovascular Diseases; Chronic Disease; Cluster Analys | 2011 |
Risk profile in chronic kidney disease stage 3: older versus younger patients.
Topics: Age Factors; Aged; Aged, 80 and over; Albuminuria; Atherosclerosis; Cardiovascular Diseases; Diabeti | 2011 |
Serum uric acid and chronic kidney disease: the Severance cohort study.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Cohort Studies; Female; Glomerular Filtration Rate; | 2012 |
Significant association between renal function and area of amyloid deposition in kidney biopsy specimens in reactive amyloidosis associated with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biomarkers; Biopsy; Blood Urea Nitrogen | 2012 |
Association between plasma levels of pigment epithelium-derived factor and renal dysfunction in patients with coronary artery disease.
Topics: Aged; Analysis of Variance; Biomarkers; C-Reactive Protein; Chi-Square Distribution; Coronary Artery | 2011 |
Uric acid and chronic kidney disease: new understanding of an old problem.
Topics: Animals; Chronic Disease; Disease Models, Animal; Humans; Kidney Diseases; Uric Acid | 2011 |
Uric acid and transplantation.
Topics: Graft Survival; Humans; Hyperuricemia; Kidney Diseases; Kidney Transplantation; Postoperative Compli | 2011 |
The association between plasma uric acid and renal function decline in a Chinese population-based cohort.
Topics: Aged; Asian People; Biomarkers; China; Chronic Disease; Cohort Studies; Female; Follow-Up Studies; G | 2012 |
[The relationship between urinary albumin excretion and serum uric acid in general population].
Topics: Adult; Aged; Albuminuria; Creatinine; Female; Humans; Kidney Diseases; Lipids; Logistic Models; Male | 2011 |
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; | 2012 |
The utility of uric acid assay in dogs as an indicator of functional hepatic mass.
Topics: Animals; Biomarkers; Case-Control Studies; Dog Diseases; Dogs; Female; Kidney Diseases; Liver Diseas | 2011 |
Elderly renal transplant recipients and renal dysfunction: a risk factor for hyperuricemia.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Creatinine; Female | 2011 |
Serum uric acid as a marker of all-cause mortality in an elderly patient cohort.
Topics: Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female | 2012 |
Association of hyperuricemia with renal outcomes, cardiovascular disease, and mortality.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Disease Progression; Female; Glomerular F | 2012 |
Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model.
Topics: Animals; Atrophy; Biomarkers; Blood Urea Nitrogen; Bone Marrow Transplantation; Cell-Derived Micropa | 2012 |
Characterization, efficacy, pharmacokinetics, and biodistribution of 5kDa mPEG modified tetrameric canine uricase variant.
Topics: Animals; Arthritis, Experimental; Biological Availability; Chemistry, Pharmaceutical; Chickens; Dise | 2012 |
[Uric acid, atherosclerosis and vascular calcifications in chronic kidney disease].
Topics: Adolescent; Adult; Aged; Atherosclerosis; Calcinosis; Cardiovascular Diseases; Chronic Disease; Como | 2012 |
Tanshinone IIA prevents uric acid nephropathy in rats through NF-κB inhibition.
Topics: Abietanes; Animals; Blood Urea Nitrogen; Chemokine CCL2; Creatinine; Drugs, Chinese Herbal; Interleu | 2012 |
Fractional excretion and reabsorption in chronic kidney disease.
Topics: Absorption; Calcium; Chronic Disease; Glomerular Filtration Rate; Homeostasis; Humans; Kidney Diseas | 2012 |
Carbon tetrachloride-induced nephrotoxicity and DNA damage in rats: protective role of vanillin.
Topics: Animals; Benzaldehydes; Carbon Tetrachloride; Catalase; Creatinine; DNA Damage; DNA Fragmentation; G | 2012 |
Anti-inflammatory and immunomodulatory effects of iridoid glycosides from Paederia scandens (LOUR.) MERRILL (Rubiaceae) on uric acid nephropathy rats.
Topics: Actins; Allopurinol; Animals; Anti-Inflammatory Agents; Benzbromarone; Chemokine CCL2; Cyclopentane | 2012 |
Age-related change in kidney function, its influencing factors, and association with asymptomatic carotid atherosclerosis in healthy individuals--a 5-year follow-up study.
Topics: Age Factors; Aged; Aging; Blood Pressure; Carotid Artery Diseases; China; Cholesterol, LDL; Cross-Se | 2012 |
Association of lead exposure, serum uric acid and parameters of renal function in Nigerian lead-exposed workers.
Topics: Adult; Creatinine; Cross-Sectional Studies; Female; Humans; Hyperuricemia; Kidney Diseases; Kidney F | 2010 |
Changes in serum urate and urate excretion with age.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; In | 2012 |
Contrast-induced nephropathy in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention.
Topics: Adult; Aged; Contrast Media; Coronary Angiography; Female; Humans; Kidney Diseases; Male; Middle Age | 2014 |
Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice.
Topics: Animals; Blood Chemical Analysis; Body Weight; Cyclooxygenase 2; Dinoprostone; Disease Models, Anima | 2013 |
Renal involvement in ankylosing spondylitis: prevalence, pathology, response to TNF-a blocker.
Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Biopsy; Chi-Square Distribution; Creatinine; Female; He | 2013 |
Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats.
Topics: Animals; Beverages; Fatty Liver; Fructokinases; Fructose; Glucose; Hypertrophy; Hyperuricemia; Insul | 2013 |
Early treatment with allopurinol in familial juvenile hyerpuricaemic nephropathy (FJHN) ameliorates the long-term progression of renal disease.
Topics: Adolescent; Adult; Allopurinol; Child; Female; Follow-Up Studies; Gout Suppressants; Humans; Kidney | 2002 |
Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cell Division; Cells, Cultured; Developed Countrie | 2002 |
A role for uric acid in the progression of renal disease.
Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr | 2002 |
A role for uric acid in the progression of renal disease.
Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr | 2002 |
A role for uric acid in the progression of renal disease.
Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr | 2002 |
A role for uric acid in the progression of renal disease.
Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr | 2002 |
Genetic mapping studies of familial juvenile hyperuricemic nephropathy on chromosome 16p11-p13.
Topics: Child; Chromosome Mapping; Chromosome Segregation; Chromosomes, Human, Pair 16; Female; Genetic Hete | 2003 |
A delta-aminolevulinic acid dehydratase (ALAD) polymorphism may modify the relationship of low-level lead exposure to uricemia and renal function: the normative aging study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Bone and Bones; Creatinine; Cross-Sectional Studies; Environm | 2003 |
Quantitative renal scintigraphy in domestic pigeons (Columba livia domestica) exposed to toxic doses of gentamicin.
Topics: Animals; Anti-Bacterial Agents; Bird Diseases; Gentamicins; Kidney; Kidney Diseases; Radionuclide Im | 2003 |
Tubular injury: the first symptom of hypertensive kidney involvement?
Topics: Acetylglucosaminidase; Adolescent; Adult; Albuminuria; Biomarkers; Female; Fructose; Glucose Toleran | 2003 |
Clinical characterization of a family with a mutation in the uromodulin (Tamm-Horsfall glycoprotein) gene.
Topics: Adolescent; Alleles; Base Pairing; Chronic Disease; Creatinine; Female; Gene Deletion; Genes, Domina | 2003 |
Ammonia, urea and uric acid content of toenails in renal insufficiency and gout.
Topics: Ammonia; Gout; Humans; Kidney Diseases; Nails; Renal Insufficiency; Urea; Uric Acid | 1953 |
[Urate kidney simulating renal tuberculosis].
Topics: Diagnosis, Differential; Humans; Kidney; Kidney Diseases; Tuberculosis; Tuberculosis, Renal; Uric Ac | 1956 |
[Urate kidney simulating renal tuberculosis].
Topics: Diagnosis, Differential; Humans; Kidney; Kidney Diseases; Tuberculosis; Tuberculosis, Renal; Uric Ac | 1956 |
[Urate kidney simulating renal tuberculosis].
Topics: Diagnosis, Differential; Humans; Kidney; Kidney Diseases; Tuberculosis; Tuberculosis, Renal; Uric Ac | 1956 |
[Urate kidney simulating renal tuberculosis].
Topics: Diagnosis, Differential; Humans; Kidney; Kidney Diseases; Tuberculosis; Tuberculosis, Renal; Uric Ac | 1956 |
Uric acid and the uricase-resistant residue in renal insufficiency.
Topics: Humans; Kidney Diseases; Renal Insufficiency; Urate Oxidase; Uric Acid | 1957 |
On serum uric acid and endogenic uric acid clearance in renal failure.
Topics: Epilepsy; Humans; Kidney Diseases; Medical Records; Renal Insufficiency; Uric Acid | 1958 |
[An attempt to determine the value of the so-called clearance test for uric acid in certain renal diseases].
Topics: Humans; Kidney Diseases; Kidney Function Tests; Uric Acid | 1958 |
[Hypouricemia: study of a case of essential nephrotic hypouricemia].
Topics: Humans; Kidney; Kidney Diseases; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid | 1958 |
Familial hyperuricaemic nephropathy.
Topics: Humans; Hyperuricemia; Kidney Diseases; Nephritis, Hereditary; Uric Acid | 1960 |
The effect of probenecid on renal excretion and plasma level of uric acid in patients with renal insufficiency.
Topics: Humans; Kidney; Kidney Diseases; Metabolic Diseases; Probenecid; Renal Elimination; Renal Insufficie | 1961 |
Uric acid nephropathy in leukemia. The use of acetazolamide in its management.
Topics: Acetazolamide; Disease Management; Humans; Kidney; Kidney Diseases; Leukemia; Uric Acid | 1962 |
[Results of histochemical studies on so-called uric acid infarct of the kidneys].
Topics: Glycosaminoglycans; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infarction; Kidney; | 1963 |
Acute uric acid nephropathy. Treatment with mannitol diuresis and peritoneal dialysis.
Topics: Dialysis; Diuresis; Humans; Kidney Diseases; Mannitol; Peritoneal Dialysis; Renal Dialysis; Uric Aci | 1963 |
[The treatment of gout crises in patients with renal insufficiency].
Topics: Colchicine; Gout; Humans; Kidney Diseases; Phenylbutazone; Renal Insufficiency; Salicylates; Uric Ac | 1963 |
[The gouty kidney].
Topics: Gout; Humans; Kidney; Kidney Diseases; Uric Acid; Urinary Calculi | 1962 |
The relationship between gout and the kidney.
Topics: Gout; Humans; Kidney; Kidney Diseases; Uric Acid | 1963 |
Bilateral uric acid calculi in polycystic kidneys.
Topics: Humans; Kidney; Kidney Diseases; Medical Records; Polycystic Kidney Diseases; Uric Acid; Urinary Cal | 1962 |
Acute urinary obstruction in the newborn. An unusual case.
Topics: Child; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kidney Diseases; Uric Acid; Urina | 1962 |
Pitfalls in the interpretation of apparent hyperuricemia.
Topics: Blood Chemical Analysis; Humans; Hyperuricemia; Kidney Diseases; Uric Acid | 1963 |
RENAL LESIONS RESULTING FROM INDUCED HYPERURICEMIA IN ANIMALS.
Topics: Animals; Blood; Dogs; Gout; Hyperuricemia; Injections; Injections, Intravenous; Kidney; Kidney Disea | 1963 |
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS.
Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; | 1964 |
URIC ACID RENAL DISEASE IN ACUTE LEUKEMIA.
Topics: Anuria; Blood Chemical Analysis; Child; Humans; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Lymph | 1964 |
[THE KIDNEY IN CHRONIC LEAD POISONING].
Topics: Edetic Acid; Electrons; Gout; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Function Tests; | 1964 |
[GOUT IN WOMEN].
Topics: Blood Chemical Analysis; Gout; Humans; Kidney Calculi; Kidney Diseases; Uric Acid; Women | 1964 |
RENAL ARTERIOLAR DISEASE IN YOUNG PRIMIPARAS.
Topics: Adolescent; Arteries; Black People; Blood Chemical Analysis; Body Weight; Eclampsia; Female; Humans; | 1964 |
[A PARTICULAR TYPE OF FUNCTIONAL RENAL INSUFFICIENCY: HYPOXIC GLOMERULO-NEPHROPATHY].
Topics: Albuminuria; Anuria; Blood Chemical Analysis; Bronchitis; Glomerulonephritis; Hemoglobins; Hypoxia; | 1964 |
ANURIA DUE TO URIC ACID CRYSTALLURIA: AN UNUSUAL COMPLICATION OF THERAPY IN THE RETICULOSES.
Topics: Abdominal Neoplasms; Anuria; Blood; Genetic Diseases, X-Linked; Humans; Kidney Diseases; Leukemia, H | 1964 |
[SECONDARY ASPECIFIC EFFECTS OF BENZOTHIAZINIC DIURETICS].
Topics: Agranulocytosis; Amylases; Blood Glucose; Chlorothiazide; Diabetes Mellitus; Diuretics; Drug Eruptio | 1964 |
BENCE JONES PROTEINEMIA.
Topics: Bence Jones Protein; Blood Protein Electrophoresis; Blood Sedimentation; Calcium; Calcium, Dietary; | 1964 |
RENAL ABNORMALITIES INDUCED BY HYDROXYUREA (NSC-32065).
Topics: Antineoplastic Agents; Blood; Hematologic Diseases; Hematuria; Hydroxyurea; Kidney Diseases; Kidney | 1964 |
THE TREATMENT OF GOUT.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Colchicine; Diet; Diet Therapy; Dr | 1964 |
GOUT.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Colchicine; Diagnosis, Differential; Diet; Diet | 1964 |
AUTONOMOUS SECONDARY (RENAL) PARATHYROID HYPERPLASIA.
Topics: Blood Chemical Analysis; Calcium Metabolism Disorders; Chlorides; Creatine; Creatinine; Humans; Hype | 1964 |
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA.
Topics: Acute Disease; Humans; Kidney Diseases; Leukemia; Purine-Pyrimidine Metabolism, Inborn Errors; Uric | 1964 |
[SECONDARY GOUT IN CHRONIC NEPHROPATHIES].
Topics: Amyloidosis; Blood; Colchicine; Drug Therapy; Gout; Humans; Hypertension; Hypertension, Renal; Kidne | 1965 |
URIC ACID EXCRETION AND RENAL FUNCTION IN THE ACUTE HYPERURICEMIA OF LEUKEMIA. PATHOGENESIS AND THERAPY OF URIC ACID NEPHROPATHY.
Topics: Acetazolamide; Bicarbonates; Blood; Carbon Isotopes; Drug Therapy; Fluids and Secretions; Hippurates | 1964 |
EXPERIMENTAL URATE NEROPATHY: STUDIES OF THE DISTRIBUTION OF URATE IN RENAL TISSUE.
Topics: Blood Chemical Analysis; Dogs; Histocytochemistry; Kidney Diseases; Kidney Function Tests; Mannitol; | 1964 |
[ON URIC ACID AND OTHER CLEARANCES AFTER INTRAVENOUS ADMINISTRATION OF FURSEMID IN MAN].
Topics: Administration, Intravenous; Diuresis; Diuretics; Drug Therapy; Humans; Injections, Intravenous; Inu | 1964 |
TOXICITY OF DIURETICS.
Topics: Blood; Diuretics; Gastrointestinal Diseases; Gout; Hematologic Diseases; Humans; Hyperglycemia; Hype | 1965 |
SERUM INDICAN IN RENAL DISEASE.
Topics: Blood; Creatine; Creatinine; Glomerulonephritis; Indican; Kidney Diseases; Nephrotic Syndrome; Urea; | 1964 |
HEMODIALYSIS FOR CHRONIC RENAL FAILURE. II. BIOCHEMICAL AND CLINICAL ASPECTS.
Topics: Anemia; Biochemical Phenomena; Biochemistry; Blood; Blood Pressure; Blood Urea Nitrogen; Calcium; Ch | 1965 |
URINARY PH IN GOUT.
Topics: Ammonia; Gout; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Periodicity; Phosphorus; Phospho | 1965 |
THE RENAL LESION IN GOUT.
Topics: Blood Chemical Analysis; Gout; Histological Techniques; Humans; Kidney; Kidney Diseases; Nephroscler | 1965 |
TETRACYCLINE NEPHROPATHY; CASE REPORT WITH RENAL BIOPSY.
Topics: Acidosis; Acidosis, Renal Tubular; Ataxia; Biopsy; Blood; Chemistry, Pharmaceutical; Glycosuria; Gly | 1965 |
[CONSERVATIVE TREATMENT OF A LARGE, RADIOLUCENT URATE KIDNEY-PELVIC CALCULUS].
Topics: Citrus; Fruit; Humans; Kidney Calculi; Kidney Diseases; Kidney Pelvis; Mineral Waters; Uric Acid | 1964 |
THE TREATMENT OF CHRONIC RENAL FAILURE BY A MODIFIED GIOVANNETTI DIET.
Topics: Blood Chemical Analysis; Diet; Diet Therapy; Dietary Proteins; Glomerular Filtration Rate; Humans; K | 1965 |
NEPHROGENIC DIABETIC INSIPIDUS AND OTHER DEFECTS OF RENAL TUBULAR FUNCTION IN SJOERGREN'S SYNDROME.
Topics: Acidosis; Acidosis, Renal Tubular; Ammonium Chloride; Diabetes Insipidus; Diabetes Mellitus; Humans; | 1965 |
METHODS OF MEASURING GLOMERULAR-FILTRATION RATE: A COMPARISON OF INULIN, VITAMIN-B 12 AND CREATININE CLEARANCES.
Topics: Cobalt Isotopes; Creatine; Creatinine; Diagnosis; Glomerular Filtration Rate; Gout; Humans; Hyperten | 1965 |
[THE ROLE OF THE NORMAL KIDNEY AND THE PATHOLOGICAL KIDNEY IN THE GENESIS OF HYPERURICEMIA].
Topics: Blood; Diuresis; Gout; Humans; Hyperuricemia; Kidney; Kidney Diseases; Kidney Function Tests; Physio | 1965 |
[RENAL ATROPHIES OF URIC LITHIASIS. CIRCUMSTANCES OF APPEARANCE, EVOLUTION OF RADIOLOGICAL STUDY OF 5 CASES].
Topics: Atrophy; Humans; Kidney; Kidney Calculi; Kidney Diseases; Lithiasis; Pathology; Radiology; Uric Acid | 1965 |
Diurnal variations in renal excretion of electrolytes, uric acid and total amino nitrogen in various renal diseases and in essential hypertension.
Topics: Electrolytes; Essential Hypertension; Humans; Hypertension; Kidney Diseases; Nitrogen; Periodicity; | 1961 |
[Urate transporter and renal hypouricemia].
Topics: Carrier Proteins; Gout; Humans; Kidney; Kidney Diseases; Mutation; Organic Anion Transporters; Organ | 2003 |
The cytoprotective role of a low-molecular-weight heparin fragment studied in an experimental model of glomerulotoxicity.
Topics: Animals; Anti-Bacterial Agents; Anticoagulants; Antioxidants; Blood Urea Nitrogen; Creatinine; Doxor | 2003 |
Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.
Topics: Carrier Proteins; Female; Genotype; Humans; Japan; Kidney Diseases; Male; Mutation; Organic Anion Tr | 2004 |
Prevention of shock wave-induced renal oxidative stress by melatonin: an experimental study.
Topics: Animals; Free Radical Scavengers; Hemorrhage; Kidney; Kidney Diseases; Leukocyte Count; Lithotripsy; | 2004 |
Preservation of uric acid infarcts in the museum.
Topics: Humans; Infarction; Kidney; Kidney Diseases; Museums; Pathology; Uric Acid | 1952 |
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia.
Topics: Adolescent; Adult; Carrier Proteins; Child; Child, Preschool; Exons; Female; Humans; Introns; Japan; | 2004 |
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese.
Topics: Adult; Aged; Base Sequence; Carrier Proteins; Cohort Studies; Female; Haplotypes; Humans; Hyperurice | 2004 |
Emergence of Talanin protein associated with human uric acid nephrolithiasis in the Hominidae lineage.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 10; Chro | 2004 |
Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.
Topics: Animals; Blood Urea Nitrogen; Cyclooxygenase 2; Disease Progression; Enzyme Induction; Female; Genes | 2004 |
Dietary fiber suppresses elevation of uric acid and urea nitrogen concentrations in serum of rats with renal dysfunction induced by dietary adenine.
Topics: Adenine; Animals; Blood Urea Nitrogen; Cellulose; Chitin; Chitosan; Creatinine; Diet; Dietary Fiber; | 2004 |
Associations among lead dose biomarkers, uric acid, and renal function in Korean lead workers.
Topics: Adolescent; Adult; Age Factors; Biomarkers; Blood Pressure; Creatinine; Drug Interactions; Female; H | 2005 |
Renal hypouricemia is an ominous sign in patients with severe acute respiratory syndrome.
Topics: Carrier Proteins; Drug Administration Schedule; Female; Humans; Immunoglobulins, Intravenous; Kidney | 2005 |
Mutational analysis of idiopathic renal hypouricemia in Korea.
Topics: Acute Kidney Injury; Adolescent; Adult; Arginine; Asian People; Base Sequence; Carrier Proteins; Chi | 2005 |
Determination of uric acid and p-aminohippuric acid in human saliva and urine using capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of renal disease.
Topics: Ascorbic Acid; Electrochemistry; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hyp | 2005 |
Can cystatin C be a better marker for the early detection of renal damage in primary hypertensive patients?
Topics: Adult; beta 2-Microglobulin; Biomarkers; Blood Urea Nitrogen; Creatinine; Cystatin C; Cystatins; Dis | 2005 |
[The features of uric acid metabolism in women in climacterium].
Topics: Adolescent; Adult; Aged; Circadian Rhythm; Female; Humans; Hyperuricemia; Kidney Diseases; Male; Men | 2005 |
Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats.
Topics: Allopurinol; Animals; Blood Pressure; Body Weight; Cholesterol; Creatinine; Enzyme Inhibitors; Heart | 2005 |
The correlation between renal function and systolic or diastolic blood pressure in severe preeclamptic women.
Topics: Adult; Blood Urea Nitrogen; Calcium; Chi-Square Distribution; Creatinine; Diastole; Female; Humans; | 2005 |
Is salt-wasting the long awaited answer to the hyperuricaemia seen in uromodulin storage diseases?
Topics: Animals; Humans; Hyperuricemia; Hyponatremia; Kidney; Kidney Diseases; Mice; Mice, Knockout; Mucopro | 2006 |
Lead blood concentrations and renal function evaluation: study in an exposed Mexican population.
Topics: Adult; Blood Proteins; Cooking and Eating Utensils; Creatinine; Cross-Sectional Studies; Environment | 2006 |
Successful living-related kidney transplantation in hereditary renal hypouricaemia.
Topics: Acute Kidney Injury; Adult; Homozygote; Humans; Kidney Diseases; Kidney Transplantation; Living Dono | 2006 |
Prognostic significance of the serum phosphorus level and its relationship with other prognostic factors in multiple myeloma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone Marrow Cells; Creatinine; Humans; Kidney Diseases; | 2006 |
A case of renal hypouricemia caused by urate transporter 1 gene mutations.
Topics: Adult; Base Sequence; Carrier Proteins; DNA; Female; Heterozygote; Humans; Intellectual Disability; | 2006 |
[Relationships between arterial hypertension, metabolic disturbances and uric acid nephropathy].
Topics: Adult; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Hyperuricemia; Insulin; Kidney D | 2006 |
Familial nephropathy associated with hyperuricemia in Spain: our experience with 3 families harbouring a UMOD mutation.
Topics: Adult; DNA Mutational Analysis; Exons; Family Health; Female; Genetic Linkage; Humans; Hyperuricemia | 2006 |
Analysis of excretion fraction of uric acid.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Chemistry, Clinical; Child; Child, Preschool; Humans; | 2006 |
Mycophenolate mofetil promotes prolonged improvement of renal dysfunction after pediatric liver transplantation: experience of a single center.
Topics: Adolescent; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; | 2007 |
Rapid detection of R90H mutations in the human urate transporter 1 gene.
Topics: Amino Acid Sequence; Base Sequence; DNA Mutational Analysis; Female; Humans; Kidney Diseases; Middle | 2007 |
Letter by Kielstein et al regarding article, "High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid".
Topics: Allopurinol; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Kidney Diseases; Oxidative S | 2007 |
Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations.
Topics: Adult; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colchicine; Diuretics; | 2007 |
[Renal manifestations in rheumatic diseases].
Topics: Amyloidosis; Diagnosis, Differential; Glomerulonephritis, IGA; Glomerulonephritis, Membranoprolifera | 2007 |
Outcome of kidney transplantation in familial juvenile hyperuricaemic nephropathy.
Topics: Adult; Cohort Studies; Family Health; Female; Follow-Up Studies; Humans; Hyperuricemia; Kidney Disea | 2007 |
Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients.
Topics: Aged; Albumins; Antioxidants; Blood Chemical Analysis; Cholestasis; Critical Illness; Female; Humans | 2007 |
NHANES III: influence of race on GFR thresholds and detection of metabolic abnormalities.
Topics: Adult; Bicarbonates; Black People; Blood Pressure; Chronic Disease; Creatinine; Differential Thresho | 2007 |
Relationship of uric acid with progression of kidney disease.
Topics: Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Disease Progression; Female; Glome | 2007 |
Clinical and biochemical profile of patients with "pure" uric acid nephrolithiasis compared with "pure" calcium oxalate stone formers.
Topics: Adult; Age of Onset; Calcium Oxalate; Female; Humans; Kidney Diseases; Male; Metabolic Clearance Rat | 2007 |
Absence of SLC22A12 gene mutations in Greek Caucasian patients with primary renal hypouricaemia.
Topics: Adult; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genotype; Greece; Humans; | 2007 |
Uric acid: a surrogate of insulin resistance in older women.
Topics: Body Mass Index; Chronic Disease; Female; Glomerular Filtration Rate; Humans; Insulin Resistance; Ki | 2008 |
The relationship between obesity and transforming growth factor beta on renal damage in essential hypertension.
Topics: Adult; Albuminuria; Blood Glucose; Body Mass Index; Case-Control Studies; Creatinine; Female; Humans | 2007 |
Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study.
Topics: Adolescent; Adult; Aged; Chronic Disease; Creatinine; Disease Progression; Europe; Female; Follow-Up | 2008 |
Uric acid and incident kidney disease in the community.
Topics: Female; Follow-Up Studies; Humans; Kidney Diseases; Male; Middle Aged; Uric Acid | 2008 |
Asymptomatic hyperuricemia: perhaps not so benign?
Topics: Cardiovascular Diseases; Gout; Humans; Hyperuricemia; Kidney Diseases; Risk Factors; Uric Acid | 2008 |
Age and origin of the G774A mutation in SLC22A12 causing renal hypouricemia in Japanese.
Topics: Age Factors; Asian People; Female; Haplotypes; Homozygote; Humans; Japan; Kidney Diseases; Linkage D | 2008 |
Uric acid--a bad acid for the kidney?
Topics: Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Regression Anal | 2008 |
Gout and the pathogenesis of its attacks.
Topics: Adult; Aged; Diagnosis, Differential; Emotions; Female; Gout; Humans; Hypersensitivity; Kidney Disea | 1967 |
[Congenital hyperuricemia in a cerebro-renal form].
Topics: Athetosis; Child; Humans; Kidney Diseases; Male; Uric Acid | 1967 |
The contribution of residual nephrons within the chronically diseased kidney to urate homeostasis in man.
Topics: Adolescent; Adult; Aged; Asian People; Biological Transport; Black People; Female; Humans; Inulin; K | 1967 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Gouty nephropathy: fact or fiction?
Topics: Gout; History, 16th Century; History, 19th Century; History, 20th Century; History, Ancient; Humans; | 1983 |
Moonshine and lead. Relationship to the pathogenesis of hyperuricemia in gout.
Topics: Adult; Alcohol Drinking; Edetic Acid; Female; Gout; Humans; Kidney Diseases; Latex Fixation Tests; L | 1983 |
Occult lead intoxication in patients with gout and kidney disease.
Topics: Adult; Aged; Alcohol Drinking; Creatinine; Edetic Acid; Female; Gout; Humans; Kidney Diseases; Lead; | 1984 |
[Gouty nephropathy (a review of the literature)].
Topics: Animals; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; Nephritis, Interstitial; Purines; Ra | 1984 |
Juvenile gouty arthritis. Two cases associated with mild renal insufficiency.
Topics: Adolescent; Arthritis; Female; Gout; Humans; Kidney Diseases; Male; Recurrence; Synovial Fluid; Uric | 1984 |
[How to treat hyperuricemia?].
Topics: Arthritis, Rheumatoid; Humans; Hypertension; Kidney Calculi; Kidney Diseases; Risk; Uric Acid | 1984 |
Side effects of systemic cyclosporine in patients not undergoing transplantation.
Topics: Adolescent; Adult; Aged; Anemia; Autoimmune Diseases; Blood Sedimentation; Chemical and Drug Induced | 1984 |
A chick model for impaired renal function.
Topics: Animals; Blood Urea Nitrogen; Chickens; Disease Models, Animal; Kidney; Kidney Diseases; Ligation; M | 1984 |
When should patients with symptomatic urinary stone disease be evaluated metabolically?
Topics: Adult; Calcium Oxalate; Colic; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Male; Recurrence | 1984 |
[Renal colic (uric acid diathesis) and pregnancy].
Topics: Adult; Colic; Diagnosis, Differential; Disease Susceptibility; Female; Humans; Kidney Diseases; Preg | 1983 |
[The gouty kidney].
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1983 |
Danger of urography in hyperuricemic children with Burkitt's lymphoma.
Topics: Abdominal Neoplasms; Adolescent; Burkitt Lymphoma; Child; Contrast Media; Humans; Kidney Diseases; M | 1983 |
Diagnosis and management of renal calculous disease.
Topics: Calcium; Colic; Female; Fluid Therapy; Humans; Kidney Calculi; Kidney Diseases; Male; Recurrence; Ur | 1983 |
Gout and uric acid nephropathy: some new aspects in diagnosis and treatment.
Topics: Adult; Diet; Female; Gout; Humans; Hypolipidemic Agents; Kidney Diseases; Male; Uric Acid; Uricosuri | 1983 |
Failure to thrive, hyperuricemia, and renal insufficiency in early infancy secondary to partial hypoxanthine-guanine phosphoribosyl transferase deficiency.
Topics: Failure to Thrive; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Kidney Diseases; Kidney T | 1984 |
Severe allopurinol toxicity. Description and guidelines for prevention in patients with renal insufficiency.
Topics: Adult; Aged; Allopurinol; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; Syndrome; | 1984 |
Piroxicam (Feldene) predisposes to chemotherapy-induced acute uric acid nephropathy.
Topics: Acute Disease; Aged; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney Diseases; Male; | 1984 |
Behaviour of serum urate in renal disease of varying etiology.
Topics: Adult; Creatinine; Female; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Male; Middle Aged; U | 1984 |
The rate of purine synthesis de nova in blood mononuclear cells in vitro from patients with familial hyperuricaemic nephropathy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Erythrocytes; Female; Gout; Humans; Kidney Disease | 1984 |
The role of lead in gout nephropathy.
Topics: Adult; Aged; Creatinine; Edetic Acid; Gout; Humans; Kidney; Kidney Diseases; Kidney Function Tests; | 1981 |
[Urate-oxidase: a new therapy of cytotoxic-drug-induced hyperuricemia (author's transl)].
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Female; Gout; Humans; Kidney Diseases; Leukemia; Ma | 1981 |
Longitudinal comparison of intermittent versus continuous ambulatory peritoneal dialysis, in the same patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Calcium; Carbon Dioxide; | 1981 |
Lead nephropathy and gout.
Topics: Adolescent; Adult; Aged; Child, Preschool; Creatinine; Female; Glomerular Filtration Rate; Gout; Hum | 1983 |
Hypouricemia and intravenous infusions.
Topics: Colic; Diuresis; Female; Humans; Infusions, Parenteral; Kidney Diseases; Male; Uric Acid | 1983 |
Familial nephropathy with hyperuricemia and gout.
Topics: Adult; Biopsy; Child; Female; Genes, Dominant; Glomerular Filtration Rate; Gout; Humans; Kidney; Kid | 1983 |
Successful medical management of bilateral ureteral obstruction due to acute uric acid nephropathy.
Topics: Allopurinol; Humans; Kidney Diseases; Male; Middle Aged; Renal Dialysis; Ureteral Obstruction; Uric | 1983 |
Hypouricemia in the hypereosinophilic syndrome. Response to treatment.
Topics: Eosinophilia; Hematuria; Humans; Kidney Diseases; Kidney Tubules; Male; Middle Aged; Proteinuria; Sy | 1983 |
Hyperuricemia and gout: an update.
Topics: Allopurinol; Female; Gout; Humans; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Middle A | 1981 |
Urate-oxidase prophylaxis of uric acid-induced renal damage in childhood leukemia.
Topics: Allopurinol; Antineoplastic Agents; Child; Child, Preschool; Diuresis; Female; Humans; Infant; Kidne | 1982 |
[Renal physiopathology of uric acid. Pharmacologic study].
Topics: Humans; Kidney Diseases; Kidney Tubules; Probenecid; Pyrazinamide; Uric Acid; Uricosuric Agents | 1982 |
[Therapy of cardiac insufficiency with diuretics].
Topics: Amiloride; Benzothiadiazines; Blood Glucose; Diuretics; Drug Administration Schedule; Female; Furose | 1982 |
[Asymptomatic hyperuricemia-when should it be treated?].
Topics: Arthritis; Cardiovascular Diseases; Gout; Humans; Kidney Calculi; Kidney Diseases; Patient Care Plan | 1982 |
[A case of familial hypouricemia].
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Tubules; Uric Acid | 1982 |
Renal and metabolic toxicities of cancer chemotherapy.
Topics: Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Electrolytes; Glomerular Filtration | 1982 |
Hepatic and renal effects of low concentrations of methoxyflurane in exposed delivery ward personnel.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical and Drug Induced Li | 1980 |
Acute obstructive uric acid nephropathy after treatment of neoplastic adenopathy.
Topics: Acute Disease; Chlorambucil; Constriction, Pathologic; Female; Humans; Kidney Diseases; Leukemia, Ly | 1981 |
The risks of asymptomatic hyperuricaemia and the use of uricosuric diuretics.
Topics: Coronary Disease; Diuretics; Humans; Kidney Calculi; Kidney Diseases; Risk; Ticrynafen; Uric Acid; U | 1981 |
[Advances in the treatment of gout and hyperuricemia].
Topics: Anti-Inflammatory Agents; Female; Gout; Humans; Hypertension; Kidney Calculi; Kidney Diseases; Male; | 1981 |
Assessment of natriuretic drugs.
Topics: Body Water; Diuretics; Humans; Hypertension; Kidney Diseases; Kidney Tubules; Male; Natriuresis; Sod | 1981 |
[Uric acid nephropathy---report of 20 cases (author's transl)].
Topics: Adult; Female; Humans; Kidney Calculi; Kidney Diseases; Male; Middle Aged; Uric Acid | 1981 |
Uric acid crystal-induced nephropathy: evidence for a specific renal lesion in a gouty family.
Topics: Adenine; Adult; Animals; Child; Child, Preschool; Female; Gout; Humans; Kidney; Kidney Diseases; Swi | 1981 |
[Renal damage following encephalitis and convulsions].
Topics: Adult; Encephalitis; Humans; Kidney Diseases; Male; Remission, Spontaneous; Seizures; Uric Acid | 1981 |
Uric acid, gout and the kidney.
Topics: Acute Kidney Injury; Adult; Animals; Female; Gout; Humans; Kidney; Kidney Diseases; Male; Middle Age | 1981 |
Current status of diagnosis and treatment of acute gouty arthritis.
Topics: Acute Disease; Adult; Arthritis; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Synovial | 1980 |
[Uric acid-induced diseases. 1. Clinical picture, forms of manifestation].
Topics: Animals; Arteriosclerosis; Gout; Humans; Kidney Calculi; Kidney Diseases; Pruritus; Rats; Risk; Syno | 1980 |
Kidney stones.
Topics: Acidosis, Renal Tubular; Calcium; Calcium Oxalate; Cystinuria; Humans; Kidney Calculi; Kidney Diseas | 1980 |
Changing trends of mortality in gout.
Topics: Aged; Arteriosclerosis; Coronary Disease; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; | 1980 |
Hyperuricemia in cyanotic congenital heart disease.
Topics: Adolescent; Adult; Allopurinol; Arthritis; Child; Child, Preschool; Gout; Heart Defects, Congenital; | 1980 |
Hereditary renal hypouricemia with hyperuricosuria and variably absorptive hypercalciuria and urolithiasis--a new syndrome.
Topics: Calcium; Humans; Kidney Calculi; Kidney Diseases; Syndrome; Uric Acid | 1980 |
Erythrocyte adenosine-deaminase activity in gout and hyperuricemia.
Topics: Adenosine Deaminase; Erythrocytes; Female; Fructose; Gout; Humans; Kidney Diseases; Male; Nucleoside | 1980 |
Gout secondary to chronic renal disease: studies on urate metabolism.
Topics: Adult; Arthritis; Chronic Disease; Female; Gout; Humans; Kidney; Kidney Diseases; Male; Middle Aged; | 1980 |
[Gout as a joint disease and as a generalized disease. Incidence, diagnosis and therapy].
Topics: Allopurinol; Colchicine; Diabetes Complications; Gout; Humans; Hypertension; Indomethacin; Kidney Di | 1980 |
Chronic gouty nephropathy: a vanishing syndrome?
Topics: Animals; Gout; Humans; Kidney Diseases; Lead Poisoning; Lesch-Nyhan Syndrome; Lymphoproliferative Di | 1981 |
[Study of the binding between uric acid and plasma proteins (author's transl)].
Topics: Blood Proteins; Electrophoresis, Agar Gel; Electrophoresis, Cellulose Acetate; Gout; Humans; Hyperli | 1980 |
Uricosuric diuretics.
Topics: Amiloride; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gout; Humans; Ind | 1980 |
[Prevention of acute urate nephropathy].
Topics: Acute Disease; Adolescent; Adult; Aged; Allopurinol; Antineoplastic Agents; Bicarbonates; Drug Thera | 1980 |
Maintaining low concentrations of plasma beta 2-microglobulin through continuous slow haemofiltration.
Topics: Aged; beta 2-Microglobulin; Biocompatible Materials; Blood Urea Nitrogen; Creatinine; Female; Hemofi | 1995 |
Enthesopathy and atypical gouty arthritis following renal transplantation: a case control study.
Topics: Adult; Arthritis, Gouty; Case-Control Studies; Creatinine; Female; Humans; Kidney Diseases; Kidney T | 1995 |
Effect of nifedipine on tubular handling of uric acid in transplanted kidney on cyclosporine A treatment.
Topics: Adolescent; Adult; Child; Creatinine; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combi | 1995 |
[Kidney involvement in industrial exposure to lead and cadmium].
Topics: Adult; Air Pollutants, Occupational; Cadmium Poisoning; Ceramics; Coloring Agents; Female; Humans; K | 1995 |
Renal urate hypoexcretion in Polynesian women is not as severe as in United Kingdom (UK) women with familial juvenile hyperuricaemic nephropathy (FJHN).
Topics: Adult; Analysis of Variance; Creatinine; Female; Gout; Humans; Kidney Diseases; Middle Aged; Polynes | 1994 |
Familial juvenile hyperuricaemic nephropathy in adolescents.
Topics: Adolescent; Adult; Diagnosis, Differential; Erythrocytes; Female; Gout; Humans; Hypoxanthine Phospho | 1994 |
Uric acid nephropathy as a presenting sign of chronic lymphocytic leukemia.
Topics: Humans; Kidney Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tumor Lysis Synd | 1995 |
Does renal impairment protect from gout?
Topics: Adult; Aged; Cohort Studies; Creatinine; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; R | 1995 |
Nonacidotic kidney proximal tubulopathy with absorptive hypercalciuria.
Topics: Amino Acids; Biopsy; Calcium; Child, Preschool; Family Health; Glucose; Humans; Kidney Diseases; Kid | 1995 |
Polynesian women are also at risk for hyperuricaemia and gout because of a genetic defect in renal urate handling.
Topics: Adult; Erythrocytes; Family; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Pentosyltrans | 1994 |
Renal function and histopathologic changes in children after liver transplantation.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Chromium Radioisotopes; Cyclosporine; Dose-Response Rel | 1994 |
[Early diagnosis of urate kidney diseases in psoriasis].
Topics: Adult; Female; Humans; Kidney Diseases; Male; Psoriasis; Time Factors; Uric Acid | 1993 |
The duration of hypertension in the puerperium of preeclamptic women: relationship with renal impairment and week of delivery.
Topics: Adult; Blood Pressure; Female; Gestational Age; Humans; Hypertension; Kidney Diseases; Parity; Postp | 1994 |
Familial interstitial nephropathy without hyperuricemia.
Topics: Adult; Aged; Biopsy; Family Health; Female; Fibrosis; Humans; Kidney; Kidney Diseases; Male; Middle | 1994 |
Hyperuricemia and urate nephropathy in urate oxidase-deficient mice.
Topics: Allopurinol; Animals; Arthritis, Gouty; Disease Models, Animal; Genes, Lethal; Humans; Kidney Calcul | 1994 |
Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate.
Topics: Benzbromarone; Citrates; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Ki | 1993 |
Renal hypouricemia with both drug-insensitive secretion and defective reabsorption of urate: a novel type of renal hypouricemia.
Topics: Adult; Creatinine; Drug Resistance; Extracellular Space; Furosemide; Humans; Inosine; Kidney Disease | 1993 |
Renal, metabolic, and hemodynamic side-effects of interleukin-2 and/or interferon alpha: evidence of a risk/benefit advantage of subcutaneous therapy.
Topics: Adult; Aged; Blood Proteins; Blood Urea Nitrogen; Creatinine; Electrolytes; Female; Hemodynamics; Hu | 1993 |
Renal hypouricemia and absorptive hypercalciuria: a real syndrome.
Topics: Adult; Biological Transport; Calcitriol; Calcium; Female; Humans; Kidney Diseases; Kidney Tubules, P | 1993 |
Plasma natriuretic factor(s) in patients with intracranial disease, renal salt wasting and hyperuricosuria.
Topics: Adult; Animals; Biological Transport; Brain Diseases; Dose-Response Relationship, Drug; Female; Huma | 1993 |
[Do hypercalciuria and hyperuricosuria produce the same tubular damage?].
Topics: Analysis of Variance; beta 2-Microglobulin; Calcium; Female; Humans; Kidney Diseases; Kidney Tubules | 1995 |
[Biochemical evaluation of renal lesions produced by electrohydraulic shock waves].
Topics: Acetylglucosaminidase; Adult; Aged; Calcium Oxalate; Calcium Phosphates; Creatinine; Female; Humans; | 1995 |
Effect of amino acid based dialysate on peritoneal blood flow and permeability in stable CAPD patients: a potential role for nitric oxide?
Topics: Adult; Aged; alpha-Macroglobulins; Amino Acids; beta 2-Microglobulin; Blood Flow Velocity; Capillary | 1996 |
Treatment of two children with hereditary tyrosinaemia type I and long-standing renal disease with a 4-hydroxyphenylpyruvate dioxygenase inhibitor (NTBC).
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Amino Acid Metabolism, Inborn Errors; Child; Cyclohexanones; En | 1996 |
[Microalbuminuria as one of the early diagnostic signs of kidney involvement in patients with a purine metabolic disorder].
Topics: Adult; Albuminuria; Female; Gout; Hematuria; Humans; Kidney Diseases; Male; Purines; Recurrence; Tim | 1996 |
N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment.
Topics: Acetylglucosaminidase; Adult; Aged; Albuminuria; Anti-Inflammatory Agents, Non-Steroidal; Antirheuma | 1997 |
Hematuria in patients with renal hypouricemia.
Topics: Adult; Aged; Aged, 80 and over; Benzbromarone; Creatinine; Female; Hematuria; Humans; Kidney Disease | 1998 |
Efficacy of allopurinol in ameliorating the progressive renal disease in familial juvenile hyperuricaemic nephropathy (FJHN). A six-year update.
Topics: Adolescent; Adult; Allopurinol; Child; Child, Preschool; Female; Follow-Up Studies; Gout Suppressant | 1998 |
[Clinical and diagnostic significance of microalbuminuria and activity of tubular enzyme N-acetyl-beta-D-glucosaminidase (NAG) determination in patients with hyperuricosuria].
Topics: Acetylglucosaminidase; Adolescent; Adult; Albuminuria; Female; Humans; Immunochemistry; Kidney Disea | 1998 |
[Case of renal hypouricemia causing exercise-induced acute renal failure].
Topics: Acute Kidney Injury; Adolescent; Exercise; Humans; Kidney Diseases; Male; Uric Acid | 1998 |
Efficacy of urate oxidase (uricozyme) in tumour lysis induced urate nephropathy.
Topics: Aged; Allantoin; Antimetabolites, Antineoplastic; Diuresis; Drug Evaluation; Female; Humans; Kidney | 1998 |
Presymptomatic detection of familial juvenile hyperuricaemic nephropathy in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gout; Humans; Kidney Diseases; Kidney Failure, C | 1998 |
[Urate clearance in the diagnosis of kidney pathology in children].
Topics: Child; Child, Preschool; Creatinine; Diagnosis, Differential; Humans; Infant; Kidney Diseases; Metab | 1998 |
[Nephritic colic due to indinavir].
Topics: Acute Kidney Injury; Adult; Aged; Analgesics; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroid | 1998 |
Lead absorption and renal dysfunction in a South African battery factory.
Topics: Acetylglucosaminidase; Adult; Aged; Biomarkers; Blood Pressure; Body Burden; Creatinine; Cross-Secti | 1998 |
Antioxidant status and dialysis: plasma and saliva antioxidant activity in patients with fluctuating urate levels.
Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Blood Proteins; Female; Humans; Kidney Diseases; Male; Mid | 1998 |
Rehabilitating role of glutathione ester on cisplatin induced nephrotoxicity.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cisplatin; Creatinine; Disease Models, Animal; Esters; G | 1999 |
[Urate affection of kidneys and metabolic disturbances in hypertensive patients].
Topics: Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; | 1999 |
Allopurinol: intravenous use for prevention and treatment of hyperuricemia.
Topics: Adult; Allopurinol; Child; Enzyme Inhibitors; Humans; Infusions, Intravenous; Kidney Diseases; Neopl | 2000 |
Localization of a gene for familial juvenile hyperuricemic nephropathy causing underexcretion-type gout to 16p12 by genome-wide linkage analysis of a large family.
Topics: Chromosome Mapping; Chromosomes, Human, Pair 16; Family Health; Female; Genetic Linkage; Genotype; G | 2000 |
Patients with renal hypouricemia with exercise-induced acute renal failure and chronic renal dysfunction.
Topics: Acute Kidney Injury; Adult; Biopsy; Exercise; Glomerular Filtration Rate; Humans; Kidney; Kidney Con | 2000 |
Involvement of macrophage migration inhibitory factor (MIF) in experimental uric acid nephropathy.
Topics: Animals; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Macrophage Migration-Inhibito | 2000 |
Potassium citrate administration ameliorates tubulointerstitial lesions in rats with uric acid nephropathy.
Topics: Animals; Kidney; Kidney Diseases; Male; Potassium Citrate; Rats; Rats, Sprague-Dawley; Uric Acid | 2001 |
[Evaluation of nephrologic "risk" in a newly diagnosed case of plasma cell dyscrasias from personal material (1994-2000)].
Topics: Adult; Aged; Aged, 80 and over; Bence Jones Protein; Creatinine; Female; Glomerular Filtration Rate; | 2000 |
Hyperuricemia exacerbates chronic cyclosporine nephropathy.
Topics: Animals; Chronic Disease; Collagen; Crystallization; Cyclosporine; Enzyme Inhibitors; Immunosuppress | 2001 |
Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene.
Topics: Alleles; Animals; Blotting, Southern; Chromosome Banding; Chromosome Inversion; Chromosome Mapping; | 2001 |
Uric acid or urate nephropathy?
Topics: Allopurinol; Azathioprine; Biopsy; Diagnosis, Differential; Drug Interactions; Humans; Kidney; Kidne | 2001 |
[Familial gout and nephropathy in a young woman. Report of one case].
Topics: Adult; Allopurinol; Female; Genetic Counseling; Gout; Gout Suppressants; Humans; Kidney Diseases; Ur | 2001 |
[Relationship between mass of the left ventricular myocardium and uric acid metabolic imbalance in patients with arterial hypertension].
Topics: Adult; Albuminuria; Body Mass Index; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Ki | 2001 |
[Urine fibrinolytic activity as an indicator of kidney damage in uric acid metabolic imbalance].
Topics: Adolescent; Adult; Creatinine; Female; Glomerular Filtration Rate; Gout; Humans; Kidney Diseases; Ma | 2001 |
Hypertension and its relation to renal function 10 years after pregnancy complicated by pre-eclampsia and pregnancy induced hypertension.
Topics: Adult; Blood Urea Nitrogen; Body Weight; Calcium; Case-Control Studies; Chronic Disease; Creatinine; | 2000 |
Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function.
Topics: Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthine; Kidn | 2001 |
Familial juvenile hyperuricemic nephropathy and autosomal dominant medullary cystic kidney disease type 2: two facets of the same disease?
Topics: Adolescent; Adult; Child; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 16; Cysts; | 2001 |
[Vesical uric acid lithiasis in a child with renal hypouricemia].
Topics: Humans; Infant; Kidney Diseases; Male; Metabolic Diseases; Uric Acid; Urinary Bladder Calculi | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma | 2001 |
[Hyperuricemia and gout--diagnosis].
Topics: Adenine; Adult; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Go | 2002 |
[Hyperuricemia and gout--treatment].
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Benzbromarone; Colchicine; Drug | 2002 |
[Study of nine severely disabled children with hypouricemia].
Topics: Adolescent; Adult; Child; Child, Preschool; Disabled Children; Female; Humans; Infant; Kidney Diseas | 2002 |
Familial juvenile hyperuricaemic nephropathy in a Caucasian family associated with inborn malformations.
Topics: Adult; Austria; Child; Congenital Abnormalities; Creatinine; Female; Humans; Hyperuricemia; Kidney D | 2002 |
Uric acid and the kidney.
Topics: Acute Kidney Injury; Ammonia; Animals; Glomerular Filtration Rate; Glutamine; Gout; Humans; Hydrogen | 1976 |
[Frequency and distribution of types of hyperlipoproteinemia with life-shortening risk factors among ambulant patients (author's transl)].
Topics: Cholesterol; Diabetes Complications; Female; Germany, West; Gout; Humans; Hyperlipidemias; Hypertens | 1975 |
Cadmium-induced proximal tubular dysfunction in a cadmium-polluted area.
Topics: Aged; Cadmium Poisoning; Environmental Pollutants; Female; Follow-Up Studies; Humans; Japan; Kidney | 1977 |
Hyperuricemic nephropathy: pathologic features and factors influencing urate deposition.
Topics: Acute Kidney Injury; Animals; Binding Sites; Crystallization; Disease Models, Animal; Diuretics; Gou | 1975 |
An alternative method for the determination of uric acid in serum.
Topics: Ascorbic Acid; Horseradish Peroxidase; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Renal Di | 1975 |
Acquired causes of hyperuricaemia.
Topics: Alcohol Drinking; Aspirin; Diet; Energy Intake; Gout; Humans; Kidney Diseases; Phenylbutazone; Uric | 1978 |
Recessive X-linked hyperuricemia with gout and renal damage, normal activity of hypoxanthine phosphoribosyltransferase and resistance to azaguanine.
Topics: Adenine Phosphoribosyltransferase; Adolescent; Adult; Azaguanine; Azathioprine; Erythrocytes; Female | 1979 |
Drug therapy reviews: pathogenesis and clinical management of hyperuricemia and gout.
Topics: Acute Disease; Allopurinol; Anti-Inflammatory Agents; Arthritis; Chronic Disease; Colchicine; Gout; | 1979 |
Office management of chronic renal disease.
Topics: Animals; Calcium; Chronic Disease; Counseling; Dietary Proteins; Dogs; Humans; Hyperkalemia; Hyperte | 1979 |
Renal outcomes of gout and hyperuricemia.
Topics: Aged; Arthritis; California; Creatinine; Female; Follow-Up Studies; Gout; Humans; Kidney Calculi; Ki | 1979 |
Familial renal hypouricaemia: two additional cases with uric acid lithiasis.
Topics: Adult; Calcium; Humans; Jews; Kidney Calculi; Kidney Diseases; Male; Pedigree; Probenecid; Pyrazinam | 1979 |
Gout and crystal-related nephropathy.
Topics: Adenine Phosphoribosyltransferase; Female; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; Le | 1979 |
[Differential diagnosis between isolated EPH gestoses and gestoses superimposed on pre-existent nephropathies. Significance of proteinuria detected during the first weeks of pregnancy].
Topics: Creatinine; Diagnosis, Differential; Erythrocytes; Female; Humans; Kidney Diseases; Leukocytes; Pre- | 1979 |
Hypertension, renal function and gout.
Topics: Adult; Glomerular Filtration Rate; Gout; Humans; Hypertension; Kidney; Kidney Diseases; Middle Aged; | 1979 |
Allopurinol toxicity.
Topics: Allopurinol; Gout; Hematologic Diseases; Humans; Kidney Diseases; Uric Acid | 1979 |
[Early diagnosis of gout].
Topics: Adult; Allopurinol; Efficiency; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Nephrocalc | 1979 |
[The effect of benzbromaron in gout patients with limited kidney function].
Topics: Adult; Aged; Benzbromarone; Benzofurans; Creatinine; Drug Evaluation; Gout; Humans; Kidney Diseases; | 1979 |
[Action in man of Pirétanide (HOE 118), a new loop diuretic].
Topics: Acid-Base Equilibrium; Administration, Oral; Adult; Aged; Blood Pressure; Body Weight; Calcium; Diur | 1979 |
[Modern differential-therapeutic aspects of the drug therapy of chronic gout].
Topics: Allopurinol; Arteriosclerosis; Citrates; Gout; Humans; Hypertension; Kidney Diseases; Obesity; Pheny | 1979 |
Acute renal failure in patients with acute leukemia.
Topics: Acute Disease; Acute Kidney Injury; Adult; Allopurinol; Female; Hemorrhage; Humans; Kidney Diseases; | 1978 |
[Diagnostic value of renal urate excretion].
Topics: Adult; Female; Gout; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Time Factors; Uric Acid | 1978 |
Purine biosynthesis de novo by lymphocytes in gout.
Topics: Adult; Allopurinol; Female; Gout; Humans; In Vitro Techniques; Kidney Diseases; Lymphocytes; Male; M | 1978 |
[Renal excretion of uric acid in chronic kidney disease (author's transl)].
Topics: Chronic Disease; Creatinine; Humans; Kidney; Kidney Diseases; Metabolic Clearance Rate; Uric Acid | 1978 |
[Various aspects of nephropathy in gout].
Topics: Adult; Age Factors; Aged; Amyloidosis; Glomerular Filtration Rate; Gout; Humans; Hypertension, Renal | 1978 |
Asymptomatic hyperuricemia: pathogenic or innocent bystander?
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1979 |
Renal function and home haemodialysis.
Topics: Adult; Aged; Calcium; Edetic Acid; Female; Glomerular Filtration Rate; Hemodialysis, Home; Humans; K | 1975 |
[Chronic lead poisoning: Lead gout with giant tophi on the skin, nephrophathy and porphyrinopathy].
Topics: Aged; Book Industry; Chronic Disease; Edetic Acid; Gout; Humans; Kidney Diseases; Lead; Lead Poisoni | 1975 |
[In-vitro study of factors modifying the activity of urate oxidase].
Topics: Aspergillus flavus; Humans; In Vitro Techniques; Kidney Diseases; Urate Oxidase; Uric Acid | 1976 |
Therapeutic approach to pancreatic extract-induced hyperuricosuria in cystic fibrosis.
Topics: Body Weight; Child; Cystic Fibrosis; Diet Therapy; Dietary Carbohydrates; Dietary Fats; Dietary Prot | 1977 |
Pancreatic extracts in the management of cystic fibrosis.
Topics: Cystic Fibrosis; Humans; Kidney Diseases; Pancreatic Extracts; Uric Acid | 1977 |
Familial hypouricemia due to isolated renal tubular defect. Attenuated response of uric acid clearance to probenecid and pyrazinamide.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules, Proximal; Probenecid; | 1977 |
[Laboratory diagnosis in kidney- and bladder diseases].
Topics: Angiography; Biopsy; Blood Proteins; Costs and Cost Analysis; Creatinine; Humans; Kidney Diseases; O | 1977 |
Possible urate nephropathy of the newborn infant as a cause of transient renal insufficiency.
Topics: Diuresis; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kidney Diseases; Pregnancy; Ur | 1977 |
Kidney in patients with abnormalities in uric acid metabolism.
Topics: Acute Disease; Aged; Animals; Dogs; Female; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; R | 1977 |
[Automatized sequential analysis systems for diagnostically relevant, clinico-chemical parameter combinations. 1. Determination of creatinine, urea and uric acid in serum and urine].
Topics: Humans; Kidney Diseases; Urea; Uric Acid | 1977 |
Uric acid infarctions in the kidneys of newborn infants. A study on the changing incidence and on oxypurine ratios.
Topics: Age Factors; Birth Weight; Chronic Disease; Female; Humans; Hypoxanthines; Hypoxia; Infant, Newborn; | 1977 |
Tubular function impairment in patients with asymptomatic hyperuricemia.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Tubules; Male; Middle Aged; Phenolsulfonphthalein; Ur | 1977 |
The gouty kidney.
Topics: Animals; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Gout; Humans; Kidney; Kidney C | 1977 |
[Renal diabetes insipidus with hyperuricemia in an infant].
Topics: Age Factors; Diabetes Insipidus; Female; Humans; Infant; Kidney Diseases; Uric Acid | 1976 |
[Chronic hypouricemia by dysfunction of the renal tubule. Observation in a case].
Topics: Adult; Humans; Kidney Diseases; Kidney Tubules; Male; Uric Acid | 1976 |
[Affected kidneys in leukemia in childhood (author's transl)].
Topics: Acute Disease; Child; Child, Preschool; Female; Humans; Kidney Diseases; Leukemia; Male; Uric Acid | 1976 |
[Diurnal rhythm changes of kidney function].
Topics: Calcium; Circadian Rhythm; Creatinine; Hemodynamics; Humans; Kidney; Kidney Diseases; Phosphates; Ph | 1976 |
Renal disease in the elderly.
Topics: Acute Kidney Injury; Aged; Calcium; Chronic Disease; Female; Humans; Hyponatremia; Kidney Calculi; K | 1976 |
Uric acid nephropathy.
Topics: Allopurinol; Emergencies; Humans; Kidney Diseases; Leukemia; Mannitol; Peritoneal Dialysis; Renal Di | 1976 |
[Serum cholesterol concentrations in various basic diseases. Studies in 2466 hospital patients].
Topics: Adult; Aged; Body Height; Body Weight; Cholesterol; Female; Hematologic Diseases; Hospital Records; | 1976 |
[Physiologic bases of the treatment of gout].
Topics: Gout; Humans; Kidney; Kidney Diseases; Uric Acid; Uricosuric Agents | 1976 |
Multiple myeloma.
Topics: Aged; Bacterial Infections; Bence Jones Protein; Blood Viscosity; Bone Diseases; Humans; Hypercalcem | 1975 |
Leukemic urate nephropathy.
Topics: Basement Membrane; Child; Crystallization; Cytoplasmic Granules; Epithelial Cells; Epithelium; Histi | 1975 |
Adenine phosphoribosyltransferase deficiency: its inheritance and occurrence in a female with gout and renal disease.
Topics: Adenine Phosphoribosyltransferase; Adolescent; Adult; Aged; Child; Child, Preschool; Erythrocytes; F | 1975 |
Antihypertensive drug therapy in USAF flying personnel.
Topics: Adult; Aerospace Medicine; Antihypertensive Agents; Electrocardiography; Gastrointestinal Hemorrhage | 1975 |
Acute uric acid nephropathy in thalassaemia.
Topics: Adult; Humans; Kidney Diseases; Kidney Pelvis; Male; Metabolic Diseases; Thalassemia; Uric Acid | 1975 |
Intrinsic renal disease leading to abnormal urate excretion.
Topics: Acute Kidney Injury; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubules; Metabol | 1975 |
The Filipino and gout.
Topics: Adolescent; Adult; Age Factors; Aged; Allopurinol; Cross-Cultural Comparison; Diet; Ethnicity; Femal | 1975 |
Long survival in sickle cell anemia.
Topics: Age Factors; Aged; Anemia, Aplastic; Anemia, Sickle Cell; Chronic Disease; Electrophoresis, Starch G | 1975 |
Nephrotoxicity of dietary ochratoxin A in broiler chickens.
Topics: Animal Feed; Animals; Chickens; Hypokalemia; Kidney Diseases; Kidney Function Tests; Male; Ochratoxi | 1975 |
[Antiblastic therapy and cytolysis in infantile leukemia].
Topics: Allopurinol; Antineoplastic Agents; Anuria; Bicarbonates; Child; Child, Preschool; Disseminated Intr | 1975 |
[Clinical picture of gout and gouty (hyperuricemic) kidney].
Topics: Adult; Gout; Hematuria; Humans; Kidney Diseases; Male; Proteinuria; Uric Acid | 1975 |
[Choice between uricosurics and inhibitors of uric acid synthesis in the treatment of gout].
Topics: Depression, Chemical; Gout; Gout Suppressants; Humans; Kidney Diseases; Uric Acid; Uricosuric Agents | 1975 |
Acute hyperuricemic nephropathy in rats. An electron microscopic study.
Topics: Animals; Disease Models, Animal; Gout; Kidney; Kidney Calculi; Kidney Diseases; Kidney Tubules; Male | 1975 |
[Proceedings: Normal values and samples of findings in kidney diseases].
Topics: Bacteriuria; Creatinine; Female; Glomerular Filtration Rate; Gout; Hematuria; Humans; Inulin; Kidney | 1975 |
[Nephrology in 1975].
Topics: Erythrocyte Aggregation; Female; Fibrin Fibrinogen Degradation Products; Glomerulonephritis; Humans; | 1975 |
[Hypouricemia].
Topics: Humans; Kidney Diseases; Metabolic Diseases; Uric Acid; Uricosuric Agents | 1975 |
A brief note on the ultrastructure of renal glomeruli in acutely hyperuricemic rats.
Topics: Animals; Kidney Diseases; Kidney Glomerulus; Male; Oxonic Acid; Rats; Uric Acid | 1976 |
Acute lobular (membranoproliferative) glomerulonephritis with hyperuricemia and obstructive uric acid nephropathy.
Topics: Adult; Capillaries; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney T | 1976 |
[Which uric acid value is in need of treatment?].
Topics: Allopurinol; Benzbromarone; Citrates; Coronary Disease; Gout; Humans; Hyperlipidemias; Hypertension; | 1976 |
[Hyperuricemia and the kidney].
Topics: Gout; Humans; Kidney Diseases; Uric Acid; Uricosuric Agents | 1976 |
Gout, uric acid and renal disease.
Topics: Arthritis; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Metabolic Diseases; Uric Acid | 1976 |
[Activity of selected enzymes in urine of workers from the repair brigades in chemical plants "Organika-Azot" in Jaworz].
Topics: Acetylglucosaminidase; Adult; Chemical Industry; Creatinine; Humans; Kidney Diseases; L-Lactate Dehy | 1992 |
Urate metabolism during bone marrow transplantation.
Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined M | 1992 |
Postnatal development of hepatic xanthine oxidase in baby pigs and turnover of purine catabolites at reduced ambient temperature.
Topics: Animals; Animals, Newborn; Cold Temperature; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kinetics; | 1992 |
Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.
Topics: Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; P | 1992 |
Two cases in whom pyrazinamide does not inhibit the uricosuric action of benzbromarone.
Topics: Adult; Benzbromarone; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Kidney; Kidney D | 1992 |
Uric acid nephropathy after radiation therapy in a patient with chronic lymphocytic leukemia.
Topics: Aged; Humans; Kidney; Kidney Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Radiation Injur | 1992 |
Renal function and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmune uveitis.
Topics: Adult; Autoimmune Diseases; Cholesterol; Creatinine; Cyclosporine; Drug Administration Schedule; Fem | 1992 |
[Secondary kidney diseases due to hyper-uric acidemia].
Topics: Gout; Humans; Kidney; Kidney Diseases; Prognosis; Ultrasonography; Uric Acid | 1992 |
[Kidney diseases associated with pregnancy toxemia].
Topics: Blood Coagulation Disorders; Female; Humans; Hypertension; Kidney; Kidney Diseases; Pre-Eclampsia; P | 1992 |
Effects of suprofen on the isolated perfused rat kidney.
Topics: Animals; In Vitro Techniques; Kidney Diseases; Molecular Structure; Perfusion; Random Allocation; Ra | 1992 |
Identification of the causes of persistent hyperuricaemia.
Topics: Humans; Kidney Diseases; Metabolic Diseases; Purines; Time Factors; Uric Acid | 1991 |
Addendum to report of partial hypoxanthine-guanine phosphoribosyl transferase deficiency.
Topics: Failure to Thrive; Humans; Hypoxanthine Phosphoribosyltransferase; Infant; Kidney Diseases; Uric Aci | 1992 |
Ultrastructural studies of the reaction of urate crystals with a cultured renal tubular cell line.
Topics: Animals; Binding Sites; Cell Line; Crystallization; Gout; Kidney Diseases; Kidney Tubules; Microscop | 1991 |
Renal urate hypoexcretion preceding renal disease in a new kindred with familial juvenile gouty nephropathy (FJGN).
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gout; Humans; Kidney; Kidney Diseases; Male; Ped | 1991 |
Familial nephropathy and gout: which comes first?
Topics: Adult; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Failur | 1991 |
Renal hypouricemia associated with hyperoxypurinemia due to decreased renal excretion of oxypurines: a new defect in renal purine transport.
Topics: Diet; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Tubules; Kinetics; Male; Middle A | 1991 |
Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts.
Topics: Adult; Aged; Bicarbonates; Citrates; Citric Acid; Colic; Follow-Up Studies; Humans; Hydrogen-Ion Con | 1991 |
Autosomal dominant transmission of gouty arthritis with renal disease in a large Japanese family.
Topics: Adult; Arthritis, Gouty; Female; Genes, Dominant; Humans; Hypoxanthine Phosphoribosyltransferase; Ja | 1991 |
Familial juvenile gouty nephropathy with renal urate hypoexcretion preceding renal disease.
Topics: Adolescent; Adult; Child; Creatinine; Female; Glomerular Filtration Rate; Gout; Humans; Kidney; Kidn | 1991 |
Immunohistological localization of apolipoproteins in the glomeruli in renal disease: specifically apoB and apoE.
Topics: Adolescent; Adult; Apolipoproteins B; Apolipoproteins E; Blood Proteins; Child; Cholesterol; Female; | 1991 |
Carrier detection of partial hypoxanthine-guanine phosphoribosyltransferase deficiency by analysis with BamHI restriction fragment length polymorphisms and oligonucleotide probes.
Topics: Base Sequence; Child; Deoxyribonuclease BamHI; DNA Probes; Erythrocytes; Female; Genetic Carrier Scr | 1990 |
Precocious familial gout.
Topics: Adult; Child; Family Health; Female; Gout; Humans; Kidney Diseases; Male; Patient Compliance; Uric A | 1990 |
Renal tubular hypouricemia: evidence for defect of both secretion and reabsorption.
Topics: Aged; Aspirin; Creatinine; Furosemide; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubule | 1990 |
Acute urate nephropathy due to partial hypoxanthine-guanine phosphoribosyl transferase deficiency.
Topics: Acute Disease; Adult; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney Diseases; Male; Uric Ac | 1990 |
Amelioration of proximal renal tubular dysfunction in type I glycogen storage disease with dietary therapy.
Topics: Adolescent; Adult; beta 2-Microglobulin; Blood Glucose; Cholesterol; Dietary Carbohydrates; Female; | 1990 |
[The clinico-morphological characteristics of psoriatic nephropathy].
Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Psoriatic; Chronic Disease; Female; Glomerulonephri | 1990 |
Uric acid handling, pregnancy and cyclosporin in renal transplant women.
Topics: Adult; Creatinine; Cyclosporins; Female; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney | 1990 |
Familial hyperuricemia and renal insufficiency.
Topics: Adolescent; Adult; Allopurinol; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Male; Pedigr | 1990 |
Uric acid nephropathy: management pearls.
Topics: Humans; Kidney Diseases; Uric Acid | 1990 |
Uric acid metabolism in children.
Topics: Animals; Biological Transport; Child; Humans; Infant, Newborn; Kidney; Kidney Diseases; Metabolic Di | 1990 |
[Use of xidifon for prevention and treatment of nephropathies with metabolic disorders in children].
Topics: Adolescent; Calcium Metabolism Disorders; Child; Child, Preschool; Cystinuria; Diphosphonates; Etidr | 1990 |
Precocious familial gout with reduced fractional urate clearance and normal purine enzymes.
Topics: Adolescent; Adult; Age Factors; Creatinine; Family; Female; Glomerular Filtration Rate; Gout; Humans | 1990 |
Evaluation of urate renal handling in humans.
Topics: Adult; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Male; Probenecid; Pyrazinamide; Uric | 1989 |
Cisplatin: nephrotoxic action in vertebrates and its prevention.
Topics: Animals; Choline; Cisplatin; Columbidae; Ethacrynic Acid; Female; Fishes; Furosemide; Kidney Disease | 1989 |
The epidemiology of the acute flank pain syndrome from suprofen.
Topics: Acute Kidney Injury; Adult; Asthma; Case-Control Studies; Exercise; Female; Humans; Incidence; Kidne | 1989 |
A model of gout nephropathy.
Topics: Animals; Cells, Cultured; Crystallization; Dogs; Gout; Kidney Diseases; Uric Acid | 1989 |
Is gout related to an alteration of the uric acid protein binding?
Topics: Arthritis, Gouty; Blood Proteins; Gout; Humans; Hypoxanthines; Kidney Diseases; Uric Acid | 1989 |
Renal handling of hypoxanthine and xanthine in normal subjects and in cases of idiopathic renal hypouricemia.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hypoxanthines; Kidney; Kidney Diseases; Male; M | 1989 |
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Creatinine; Elec | 1989 |
Renal effects of trimethoprim in ciclosporin- and azathioprine-treated kidney-allografted patients.
Topics: Adult; Aged; Azathioprine; beta 2-Microglobulin; Creatinine; Cyclosporins; Drug Interactions; Glomer | 1989 |
Prevention of urate nephropathy in the tumour lysis syndrome.
Topics: Adolescent; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Diuresis; Hum | 1989 |
[Dietary change aids in hyperuricemia. Kidney damage--denial of alcohol--allopurinol].
Topics: Allopurinol; Diet Therapy; Female; Food, Formulated; Humans; Kidney Diseases; Male; Temperance; Uric | 1989 |
[Kidney tubular transport disorders. Disorders of renal urate transport].
Topics: Acid-Base Imbalance; Biological Transport; Extracellular Space; Gout; Humans; Kidney; Kidney Disease | 1989 |
Gout and hyperuricaemia in patients on cyclosporin and diuretics.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporins; Diuretics; Female; Gout; Humans; Kidney Dis | 1985 |
Cyclosporin, uric acid, and the kidney.
Topics: Adult; Creatinine; Cyclosporins; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; Pred | 1985 |
Non-responsiveness to allopurinol in renal hypouricaemia.
Topics: Allopurinol; Female; Humans; Kidney Diseases; Kidney Tubules; Male; Metabolic Clearance Rate; Middle | 1989 |
Renal involvement follows cardiac enlargement in essential hypertension.
Topics: Adult; Cardiac Output; Cardiomegaly; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Age | 1986 |
[Phosphorus-calcium metabolism in urate nephropathies in childhood].
Topics: Calcium; Child; Child, Preschool; Humans; Infant; Kidney Diseases; Phosphorus; Purines; Russia; Urba | 1988 |
Gout and hyperuricemia: diagnosis and management.
Topics: Adult; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Colchicine; Female; Gout; Hu | 1986 |
Asymptomatic hyperuricaemia.
Topics: Gout; Humans; Kidney Diseases; Male; Risk Factors; Uric Acid | 1987 |
Disturbances of the excretion of uric acid in workers at high risk from lead exposure.
Topics: Aminolevulinic Acid; Hemoglobins; Humans; Kidney Diseases; Lead; Male; Occupational Diseases; Occupa | 1988 |
Use of polyethylene glycol-modified uricase (PEG-uricase) to treat hyperuricemia in a patient with non-Hodgkin lymphoma.
Topics: Drug Administration Schedule; Humans; Injections, Intramuscular; Kidney Diseases; Leukemia, Lymphocy | 1988 |
Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia.
Topics: Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Kidney Diseases; Male; Middle Aged; Pyra | 1988 |
[Hyperuricemia as a risk factor of nephropathy in gout].
Topics: Adult; Aged; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Risk Factors; Uric Acid | 1988 |
Renal hypouricemia due to an isolated renal defect of urate transport.
Topics: Adult; Benzbromarone; Humans; Kidney; Kidney Diseases; Male; Pyrazinamide; Uric Acid | 1988 |
Suprofen-induced uricosuria. A potential mechanism for acute nephropathy and flank pain.
Topics: Acute Disease; Adult; Humans; Kidney Concentrating Ability; Kidney Diseases; Male; Pain; Phenylpropi | 1988 |
Vasopressin-resistant diabetes insipidus, liver dysfunction, hyperuricemia and decreased renal function. A case report.
Topics: Adult; Diabetes Insipidus; Female; Hepatitis; Humans; Kidney Diseases; Pregnancy; Pregnancy Complica | 1987 |
[Some biochemical changes in renal impairment].
Topics: Ammonia; Guanidines; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Uric Acid | 1987 |
Renal dysfunction in Brazilian lead workers.
Topics: Adult; Creatinine; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Function Tests; Lead | 1987 |
Hypouricemia due to subtotal defect in the urate transport.
Topics: Adult; Biological Transport; Female; Humans; Kidney Diseases; Kidney Tubules; Probenecid; Pyrazinami | 1987 |
[Substantiation and effectiveness of the use of purine antagonists in gouty nephropathy].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Gout; Humans; Kidney Diseases; Mercaptopurine; Middl | 1987 |
[Beta 2-microglobulin in the blood serum and urine of patients with interstitial kidney lesions].
Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; beta 2-Microglobulin; Chronic Disease; Female; Gout; Hu | 1986 |
Hyperuricemia and uric acid nephropathy.
Topics: Aged; Allopurinol; Female; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Nephritis, Inters | 1987 |
Renal disease from excess uric acid.
Topics: Chronic Disease; Humans; Kidney Diseases; Nephrons; Uric Acid; Urinary Calculi | 1987 |
Renal tolerance of rubidium chloride: short-term clinical evaluation.
Topics: Aged; Chlorides; Creatinine; Electrolytes; Enzymes; Female; Humans; Kidney Diseases; Middle Aged; Ru | 1987 |
[Molecular genetic mechanisms of the pathogenesis of gout and gouty nephropathy].
Topics: Adult; Aged; Creatine; DNA Repair; DNA Replication; Gout; Humans; Kidney Diseases; Male; Middle Aged | 1987 |
Calcium nephrolithiasis and renal tubular hypouricemia.
Topics: Adult; Calcium; Female; Humans; Hyperoxaluria; Kidney Calculi; Kidney Diseases; Kidney Tubules; Midd | 1987 |
Renal hypouricaemia in a patient with 48,XXYY syndrome.
Topics: Adult; Humans; Kidney Diseases; Male; Sex Chromosome Aberrations; Syndrome; Uric Acid | 1986 |
Hypouricemia due to renal tubular defect.
Topics: Calcium; Humans; Kidney Diseases; Kidney Tubules; Uric Acid | 1986 |
Changes in some kidney functions in experimentally lead-poisoned goats.
Topics: Animals; Calcium; Creatinine; Female; Goats; Kidney Diseases; Lead Poisoning; Phosphorus; Potassium; | 1986 |
Hyperuricemia and hypoalbuminemia predispose to cisplatin-induced nephrotoxicity.
Topics: Cisplatin; Creatinine; Humans; Hypoproteinemia; Kidney Diseases; Serum Albumin; Uric Acid | 1986 |
Requiem for gouty nephropathy.
Topics: Acute Disease; Aged; Animals; Chronic Disease; Disease Models, Animal; Gout; Humans; Kidney; Kidney | 1986 |
[Arterial hypertension in gouty nephropathy].
Topics: Adult; Aged; Blood Pressure; Female; Gout; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; | 1986 |
The clinical spectrum of gouty arthritis in women.
Topics: Adult; Age Factors; Aged; Arthritis; Diuretics; Female; Gout; Humans; Kidney Diseases; Male; Menopau | 1986 |
[Hyperuricemic nephropathy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged | 1986 |
Familial renal hypouricemia with intact reabsorption of uric acid.
Topics: Adult; Female; Humans; Kidney Diseases; Kidney Tubules; Male; Middle Aged; Probenecid; Pyrazinamide; | 1987 |
[Clinical picture and diagnosis of gout].
Topics: Adult; Aged; Diagnosis, Differential; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Uric | 1986 |
Blood chemistry in deficiency of kidney-yin and deficiency of kidney-yang types of subacute systemic lupus erythematosus.
Topics: Adult; Blood Proteins; Blood Urea Nitrogen; Creatinine; Female; Humans; Kidney Diseases; Lupus Eryth | 1985 |
[Coexistence of constitutional hyperbilirubinemia and familial hypouricemia of renal origin in a Quebec family].
Topics: Adult; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Kidney Diseases; Male; Middl | 1985 |
Hereditary renal hypouricemia in children.
Topics: Benzbromarone; Child; Child, Preschool; Creatinine; Humans; Kidney Diseases; Kidney Tubules; Metabol | 1985 |
[Behavior of serum acid levels in children in comparison with adults and the incidence of purine metabolism disorders and concomitant diseases in children of families with gout].
Topics: Adolescent; Adult; Child; Child, Preschool; Cholesterol; Female; Glomerular Filtration Rate; Gout; H | 1985 |
Hypouricemia due to renal tubular defect. A study with the probenecid-pyrazinamide test.
Topics: Adult; Calcium; Creatinine; Female; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; | 1985 |
The physiology of the renal tract in pregnancy.
Topics: Blood Urea Nitrogen; Blood Volume; Creatinine; Female; Glomerular Filtration Rate; Glucose; Glycosur | 1985 |
[Clinical course of familial hyperuricemic lesions of the kidneys].
Topics: Adolescent; Adult; Female; Humans; Kidney Diseases; Male; Uric Acid | 1985 |
Gout nephropathy and arterial hypertension.
Topics: Female; Glomerular Filtration Rate; Gout; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; | 1985 |
Role of alcohol in clinical nephrology.
Topics: Acute Kidney Injury; Alcoholism; Blood Glucose; Blood Proteins; Energy Metabolism; Female; Fetal Alc | 1985 |
Automated computerized metabolic profiles and subclinical tubular and glomerular nephropathy.
Topics: Albumins; Alkaline Phosphatase; Amylases; Blood Glucose; Blood Urea Nitrogen; Calcium; Cholesterol; | 1968 |
[Serum uric acid levels and renal function (author's transl)].
Topics: Chromium Radioisotopes; Creatinine; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Kidney; | 1973 |
[Fundamentals of gout research (author's transl)].
Topics: Arthritis; Chemical Phenomena; Chemistry; Diet Therapy; Gout; Humans; Kidney Calculi; Kidney Disease | 1974 |
[Hyperuricemia and gout in childhood (Lesch-Nyhan syndrome)].
Topics: Adolescent; Athetosis; Brain; Child; Child, Preschool; Compulsive Behavior; Gout; Humans; Huntington | 1971 |
Dietary treatment of chronic renal failure. Experiences with a modified Giovannetti diet.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Aged; Arteritis; Dietary Proteins; Edema; Female; | 1965 |
Monilial septicaemia in acute leukaemia. Successful treatment in a case complicated by acute uric acid nephropathy.
Topics: Acetazolamide; Adolescent; Amphotericin B; Candidiasis; Humans; Infectious Mononucleosis; Kidney Dis | 1966 |
[Diet therapy in gout].
Topics: Diet Therapy; Diuresis; Gout; Humans; Hypersensitivity; Kidney Diseases; Obesity; Purines; Uric Acid | 1969 |
Ammonium acid urate calculus in a cat with a high uric acid excretion possibly due to a renal tubular reabsorption defect.
Topics: Animals; Calcium Carbonate; Castration; Cat Diseases; Cats; Female; Kidney Diseases; Quaternary Ammo | 1970 |
Medical Grand Rounds from the University of Alabama Medical Center. Lead poisoning.
Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Anemia, Macrocytic; Brain Diseases; Diagnosi | 1972 |
Pathology of gout.
Topics: Allopurinol; Arthritis; Calcium Phosphates; Cartilage, Articular; Chondrocalcinosis; Crystallization | 1973 |
Effects of a high protein, "carbohydrate-free" diet on liver and kidney constituents and kidney function in chicks.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chickens; Dietary Proteins; Hypertrophy; Kidney; Ki | 1971 |
Interference by urate in the determination of plasma glucose.
Topics: Animals; Blood Glucose; Chickens; Fatty Liver; Female; Kidney Diseases; Male; Methods; Poultry Disea | 1974 |
Renal disease and urate excretion.
Topics: Humans; Kidney Diseases; Uric Acid | 1974 |
Serum urate levels and uric acid clearance in obstructive and non-obstructive nephropathies.
Topics: Glomerular Filtration Rate; Humans; Hydronephrosis; Kidney Diseases; Uric Acid | 1974 |
[Effects of coffee during good health and in disease from the medical standpoint].
Topics: Acute Disease; Aged; Blood Pressure; Caffeine; Cerebrovascular Disorders; Coffee; Diabetes Mellitus; | 1974 |
[Urate clearance in the diagnosis of uricopathy].
Topics: Adult; Aged; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; Purines; Sex Factors; U | 1974 |
[Concentration of uric acid in the serum. Interrelationship between uric acid and age, weight, height, serum lipids, liver function, glucose tolerance as well as basic disorders].
Topics: Adult; Age Factors; Aged; Body Height; Body Weight; Cardiovascular Diseases; Female; Gastrointestina | 1974 |
[Clearance of urates as a diagnostic tool in gout].
Topics: Adult; Age Factors; Aged; Blood Pressure; Creatine; Female; Gout; Humans; Kidney; Kidney Diseases; M | 1974 |
Understanding hyperuricemia: nursing implications.
Topics: Allopurinol; Diabetes Mellitus; Diet Therapy; Gout; Humans; Kidney Diseases; Metabolic Diseases; Uri | 1972 |
Peritoneal dialysis in acute uric acid nephropathy.
Topics: Acute Disease; Adult; Female; Humans; Kidney Diseases; Leukemia, Lymphoid; Peritoneal Dialysis; Uric | 1972 |
[Certain cases of acute leukemia in children with hyperleukocytosis in the peripheral blood and increased risk of development of uric acid nephropathy].
Topics: Acute Kidney Injury; Adolescent; Female; Histocytochemistry; Humans; Kidney Diseases; Leukemia, Lymp | 1974 |
Hypouricaemia and proximal renal tubular dysfunction in acute myeloid leukaemia.
Topics: Amino Acids; Calcium; Creatinine; Cytarabine; Daunorubicin; Female; Humans; Hydrogen-Ion Concentrati | 1974 |
[Letter: Hyperuricemia in hematological pathology. Therapy and prevention using urate oxidase].
Topics: Adolescent; Female; Humans; Kidney Diseases; Kidney Function Tests; Leukemia; Leukemia, Lymphoid; Le | 1974 |
[Contribution to differential diagnosis of crystalline precipitates in renal tissue].
Topics: Autopsy; Calcium; Crystallography; Cystine; Diagnosis, Differential; Histological Techniques; Humans | 1972 |
[The kidney and hyperuricemia].
Topics: Female; Glomerular Filtration Rate; Gout; Humans; Hypertension; Kidney Diseases; Kidney Function Tes | 1972 |
Self-induced secondary hyperaldosteronism simulating Bartter's syndrome.
Topics: Adult; Alkalosis; Diagnosis, Differential; Female; Furosemide; Humans; Hyperaldosteronism; Hypertrop | 1972 |
[Kidney involvement in gout].
Topics: Adolescent; Adult; Aged; Allopurinol; Anti-Bacterial Agents; Antihypertensive Agents; Female; Gout; | 1972 |
[Gout in women].
Topics: Adult; Age Factors; Female; Gout; Humans; Kidney Diseases; Male; Menopause; Middle Aged; Obesity; Se | 1972 |
[Prognosis and prevention of gout complications].
Topics: Adult; Aged; Arteriosclerosis; Diseases in Twins; Female; Gout; Humans; Kidney Calculi; Kidney Disea | 1972 |
Management of gout.
Topics: Anti-Inflammatory Agents; Arthritis; Diet; Gout; Humans; Kidney Diseases; Phagocytes; Synovial Fluid | 1972 |
Management of renal disease in pregnancy.
Topics: Acute Disease; Anti-Infective Agents, Urinary; Bacteriuria; Chronic Disease; Diabetic Nephropathies; | 1972 |
Nephrotoxicity of amphotericin B, with emphasis on changes in tubular function.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Amphotericin B; Blastomycosis; Carbon Dioxide; Glome | 1972 |
Urate deposition disease. How is it regulated and how can it be modified?
Topics: Animals; Blood Proteins; Disease Models, Animal; Gout; Humans; Hydrogen-Ion Concentration; Kidney; K | 1973 |
[Changes between 1948 and 1970 in the epidemiology and clinical features of primary gout].
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Blood Protein Disorders; Diabetes Complications; Fatty L | 1973 |
[Arterial hypertension with convulsive seizures in a patient with right kidney hypoplasia and gout attacks and with a probable gouty kidney].
Topics: Electrocardiography; Gout; Headache; Heart; Humans; Hydronephrosis; Hypertension; Kidney; Kidney Dis | 1973 |
[Treatment with allopurinol in gout and hyperuricemic renal disease].
Topics: Adult; Aged; Allopurinol; Creatinine; Female; Glomerular Filtration Rate; Gout; Humans; Hypertension | 1973 |
Platelets and vascular disease in gout.
Topics: Allopurinol; Analgesics; Arteriosclerosis; Blood Platelets; Colchicine; Diabetes Complications; Gout | 1973 |
Combined nephrotoxicity of gentamicin and methoxyflurane anaesthesia in man. A case report.
Topics: Anesthesia, Inhalation; Blood Urea Nitrogen; Body Weight; Creatinine; Drug Synergism; Fluorides; Gen | 1973 |
[Long-term therapy of gout and hyperuricemia].
Topics: Allopurinol; Arteriosclerosis; Blood Protein Disorders; Citrates; Colchicine; Diabetes Mellitus; Die | 1973 |
Correlates and consequences of asymptomatic hyperuricemia.
Topics: ABO Blood-Group System; Adult; Aspartate Aminotransferases; Blood Glucose; Calcium; Cholesterol; Cre | 1973 |
Uric acid nephropathy in shocked rats after blocking of uricase activity with triazine compounds.
Topics: Animals; Kidney; Kidney Diseases; Rats; Shock; Triazines; Urate Oxidase; Uric Acid | 1973 |
[Renal factor in the development of hyperuricacidemia].
Topics: Gout; Humans; Kidney; Kidney Diseases; Uric Acid | 1973 |
Peritoneal dialysis with fructose dialysate. Prevention of hyperglycemia and hyperosmolality.
Topics: Blood; Diabetic Nephropathies; Fructose; Glucose; Humans; Hydrogen-Ion Concentration; Hyperglycemia; | 1973 |
Pregnancy bacteriuria: the significance of site of infection.
Topics: Anemia; Antibodies, Bacterial; Bacteriuria; Female; Fetal Death; Humans; Hypertension; Kidney Diseas | 1973 |
Metabolic studies of low protein diets in uremia. I. Nitrogen and potassium.
Topics: Adult; Blood; Blood Urea Nitrogen; Body Weight; Chronic Disease; Diet; Diet Therapy; Dietary Protein | 1973 |
[Renal complications of gout].
Topics: Diet Therapy; Gout; Humans; Kidney Diseases; Uric Acid | 1973 |
Impairment of kidney function during aflatoxicosis.
Topics: Aflatoxins; Animals; Blood; Blood Urea Nitrogen; Chickens; Chlorides; Hydrogen-Ion Concentration; Ki | 1973 |
Xanthinuria in a large kindred.
Topics: Adult; Aged; Calculi; Female; Heterozygote; Humans; Kidney Diseases; Male; Middle Aged; Pedigree; Pu | 1973 |
Hyperuricaemia and urate nephropathy in haemoblastoses.
Topics: Allopurinol; Humans; Kidney Diseases; Leukemia; Uric Acid | 1973 |
Urolithiasis and nephropathy in gout.
Topics: Adult; Aged; Albuminuria; Female; Gout; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Ur | 1973 |
[Hyperuricemia. (Etiopathogenic and therapeutic concepts)].
Topics: Diuretics; Gout; Humans; Hypertension; Hypothyroidism; Kidney Diseases; Nicotinic Acids; Nucleoprote | 1973 |
Uric acid and the kidney.
Topics: Aged; Allopurinol; Animals; Diabetes Mellitus; Gout; Humans; Hydrogen-Ion Concentration; Hypercholes | 1973 |
Erythrocytosis associated with chronic renal disease.
Topics: Adult; Biopsy; Blood Urea Nitrogen; Blood Volume Determination; Creatinine; Erythrocyte Count; Glome | 1974 |
Changes in serum uric acid related to the dose of methoxyflurane.
Topics: Anesthesia, General; Dose-Response Relationship, Drug; Fluorides; Halothane; Humans; Kidney Diseases | 1974 |
[Allopurinol treatment of gout with special reference to patients with gouty nephropathy].
Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Uric Acid | 1974 |
The binding of urate to plasma proteins.
Topics: Allopurinol; Aspirin; Binding Sites; Blood Proteins; Colchicine; Dialysis; Evaluation Studies as Top | 1974 |
The clinical significance of hypouricemia.
Topics: Allopurinol; Amino Acids; Aspirin; Autoanalysis; Creatinine; Glycosuria; Humans; Kidney Diseases; Ne | 1974 |
Suppression of uric acid secretion in a patient with renal hypouricemia.
Topics: Circadian Rhythm; Creatinine; Female; Humans; Kidney Diseases; Middle Aged; Probenecid; Purine-Pyrim | 1974 |
A preliminary report of nephropathy in hyperuricemic rats.
Topics: Animals; Body Weight; Disease Models, Animal; Gout; Kidney; Kidney Calculi; Kidney Diseases; Kidney | 1974 |
Use of metolazone, a new diuretic, in patients with renal disease.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Creatinine; Diu | 1974 |
Extracorporeal renal transplantation in man.
Topics: Adult; Azathioprine; Calcium; Child; Creatinine; Forearm; Glomerulonephritis; Glycosuria; Hematology | 1968 |
Cholecystography and nephrotoxicity.
Topics: Animals; Cholecystography; Dogs; Haplorhini; Kidney; Kidney Diseases; Species Specificity; Uric Acid | 1971 |
Renal effects of low-dose methoxyflurane with cardiopulmonary bypass.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Blood Urea Nitrogen; Creatinine; Extracorporeal Circulat | 1972 |
Medical management of gout.
Topics: Adult; Allopurinol; Colchicine; Diet Therapy; Female; Gout; Humans; Kidney Diseases; Male; Middle Ag | 1972 |
Lead poisoning in rural Scotland.
Topics: Adult; Aged; Anemia; Female; Humans; Kidney Diseases; Lead; Lead Poisoning; Male; Middle Aged; Rural | 1972 |
Nephrotoxicity of amphotericin B, with emphasis on changes in tubular function.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Amphotericin B; Blastomycosis; Carbon Dioxide; Glome | 1972 |
Nephropathy, xanthinuria, and orotic aciduria complicating Burkitt's lymphoma treated with chemotherapy and allopurinol.
Topics: Allopurinol; Autopsy; Burkitt Lymphoma; Child; Cyclophosphamide; Humans; Kidney; Kidney Diseases; Ma | 1972 |
Anthralin toxicity.
Topics: Alkaline Phosphatase; Anthracenes; Anti-Infective Agents, Local; Aspartate Aminotransferases; Blood | 1972 |
[Missed gout].
Topics: Arteriosclerosis; Arthritis, Rheumatoid; Diagnosis, Differential; Gout; Humans; Hypertension; Kidney | 1972 |
Hyperuricemia in health and disease.
Topics: Arteriosclerosis; Arthritis; Blood Group Antigens; Carbohydrate Metabolism; Diabetes Complications; | 1972 |
Juvenile gout.
Topics: Adolescent; Adult; Age Factors; Bacteriuria; Child; Child, Preschool; Creatinine; Female; Gout; Huma | 1971 |
Proteinuria and mild glucose intolerance.
Topics: Adult; Age Factors; Aged; Blood Glucose; Blood Urea Nitrogen; Body Weight; Creatinine; Fasting; Fema | 1971 |
Renal complications in multiple myeloma: pathophysiology and some aspects of clinical management.
Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Aged; Allopurinol; Amyloidosis; Bence Jones Protein; B | 1971 |
[Uninterrupted therapy of hyperuricemia and gout].
Topics: Gout; Humans; Kidney Diseases; Uric Acid; Uricosuric Agents | 1971 |
[Uric acid abnormalities in juveniles. Peculiarities of the clinical picture].
Topics: Adolescent; Adult; Diabetes Complications; Diagnosis, Differential; Fatty Liver; Gout; Humans; Hyper | 1971 |
Urinary calculi. Clinical, biochemical and radiological studies in 619 patients.
Topics: Adolescent; Adult; Age Factors; Aged; Australia; Calcium; Child; Cystinuria; Diarrhea; Female; Human | 1971 |
Hyperuricemia and gout in an employee population.
Topics: Adult; Age Factors; Alcoholism; Coronary Disease; Diabetes Complications; Diuretics; Gout; Humans; H | 1971 |
[Renal functional disorders in patients with uric acid diathesis and their dynamics under treatment in Essentuki].
Topics: Adult; Female; Health Resorts; Humans; Kidney Diseases; Male; Metabolic Diseases; Middle Aged; Oxala | 1971 |
[Determination of uric acid in blood. Experimental determination; critical studies of the technics and results].
Topics: Adolescent; Adult; Aspirin; Autoanalysis; Female; Gout; Humans; Indicators and Reagents; Kidney Dise | 1971 |
[Non-protein nitrogen in the serum of patients with endemic nephropathy].
Topics: Adult; Blood Urea Nitrogen; Creatinine; Humans; Kidney Diseases; Middle Aged; Uric Acid | 1970 |
Lactic acid and hyperuricemia of faulty renal urate transport.
Topics: Female; Glycogen Storage Disease; Gout; Humans; Hypertension; Kidney Diseases; Lactates; Pre-Eclamps | 1967 |
Prevention and management of acute hyperuricemia in childhood leukemia.
Topics: Acetazolamide; Acute Disease; Adolescent; Allopurinol; Bicarbonates; Blood Urea Nitrogen; Child; Cre | 1968 |
Lysozymuria and renal tubular dysfunction in monocytic and myelomonocytic leukemia.
Topics: Acidosis, Renal Tubular; Adult; Aged; Ammonia; Calcium; Chlorides; Creatinine; Female; Humans; Hydro | 1969 |
Renal function in obese hyperuricaemic Maoris.
Topics: Adult; Chronic Disease; Creatinine; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged; New | 1969 |
Metabolic aberrations in gout.
Topics: Female; Glycogen Storage Disease Type I; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; Male | 1970 |
Prolonged nephrogram due to hyperuricaemia.
Topics: Female; Humans; Kidney; Kidney Diseases; Leukemia, Myeloid, Acute; Metabolic Diseases; Spleen; Uric | 1971 |
[Gout. Clinical analysis of 300 cases of urate gout].
Topics: Adult; Age Factors; Biopsy; Colchicine; Creatinine; Diagnosis, Differential; Diet; Diuretics; Female | 1968 |
Platelet aggregation in several cardiovascular diseases determined with a modified screen filtration pressure method.
Topics: Adenine Nucleotides; Adolescent; Adult; Blood Platelets; Cardiovascular Diseases; Cell Aggregation; | 1970 |
[Gout from the view of a special hospital for rheumatic patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Austria; Child; Cholesterol; Colchicine; Colic; Diabetes Com | 1971 |
Nephrotoxic effect of MSG (monosodium glutamate) in the chicken.
Topics: Acute Kidney Injury; Animals; Atrophy; Body Weight; Chickens; Edema; Extremities; Gallbladder; Gluta | 1971 |
[Apparently primary kidney disease revealing latent error of purine metabolism in 2 adolescents].
Topics: Adolescent; Adult; Allopurinol; Diet Therapy; Diet, Sodium-Restricted; Diuretics; Gout; Humans; Kidn | 1969 |
Renal complications of lymphoma.
Topics: Adult; Aged; Amyloidosis; Female; Humans; Hydronephrosis; Hypercalcemia; Hypertension, Renal; Kidney | 1969 |
[Clinical findings and therapy of gout with special reference to the metabolic effects of sulfinpyrazone (Anturan) and allopurinol (Zyloric)].
Topics: Allopurinol; Diabetes Mellitus; Gout; Humans; Hypertension; Kidney Diseases; Male; Sulfinpyrazone; U | 1969 |
[Familial encephalopathy with hyperuricemia. A study of purine metabolism and therapeutic attempts].
Topics: Brain Diseases; Child, Preschool; Electroencephalography; Follow-Up Studies; Gout; Humans; Infant; K | 1969 |
[Renal scintiscanning and curves of urinary and hematic activity in the renal, peripheral and hepatic areas in presenile and senile gout].
Topics: Aged; Blood Circulation; Diuresis; Female; Gout; Humans; Kidney; Kidney Diseases; Kidney Function Te | 1969 |
[Action of propaxoline on hemodynamics and renal function in normal and pathological conditions].
Topics: Adolescent; Adult; Aged; Blood Urea Nitrogen; Creatinine; Electrolytes; Female; Hemodynamics; Humans | 1969 |
[Inhibition of endogenous synthesis of uric acid with allopurinol in patients with gout and urate diathesis].
Topics: Adult; Aged; Allopurinol; Disease Susceptibility; Gout; Humans; Kidney Calculi; Kidney Diseases; Kid | 1969 |
Hyperuricaemia in northern Finland. An epidemiological study of serum uric acid in rural, urban and hospital populations.
Topics: Adolescent; Adult; Age Factors; Aged; Anemia; Body Weight; Cerebrovascular Disorders; Cholesterol; C | 1969 |
Long-term use of allopurinol in the treatment of gout.
Topics: Adolescent; Aged; Allopurinol; Colic; Female; Gout; Humans; Kidney Diseases; Male; Middle Aged; Sulf | 1970 |
The binding of urate to plasma proteins determined by means of equilibrium dialysis.
Topics: Aspirin; Blood Proteins; Dialysis; Gout; Humans; Hydrogen-Ion Concentration; Hypoxanthines; Kidney D | 1970 |
Hyperuricemia and neurologic deficits. A family study.
Topics: Adult; Ataxia; Deafness; Erythrocytes; Female; Humans; Kidney Diseases; Kidney Function Tests; Male; | 1970 |
[Enzymopathic gout. Dyspurinia due to hypoxanthine-guanine-phosphoribosyl-transferase deficiency. Occurrence and clinical characteristics of enzyme repression].
Topics: Adenine; Adult; Age Factors; Allopurinol; Enzyme Repression; Female; Gout; Guanine; Humans; Hypoxant | 1970 |
Clinical significance of hyperuricemia in routinely screened hospitalized men.
Topics: Acidosis; Adult; Aged; Autoanalysis; Diuretics; Gout; Heart Failure; Hospitalization; Humans; Kidney | 1970 |
[Study of some erythrocytic enzyme and metabolic activities in chronic nephropathies].
Topics: Acetylcholinesterase; Anemia; Chronic Disease; Erythrocytes; Glucosephosphate Dehydrogenase; Glutath | 1970 |
The importance of renal damage due to hyperuricaemia and its prevention by allopurinol.
Topics: Allopurinol; Humans; Kidney; Kidney Calculi; Kidney Diseases; Uric Acid | 1970 |
A method for the determination of plasma guanase on finger-tip blood.
Topics: Aminohydrolases; Drug Stability; Erythrocytes; Fingers; Guanine; Hepatitis A; Humans; Kidney Disease | 1970 |
Study of urinary excretion of nitrogenous compounds and their interrelationship in some diseased states.
Topics: Child; Creatine; Creatinine; Humans; Kidney Diseases; Liver Diseases; Male; Muscular Dystrophies; Ni | 1970 |
[The uric acid stone and its differential diagnosis].
Topics: Aneurysm; Contrast Media; Cystine; Diagnosis, Differential; Hemorrhage; Humans; Kidney Calculi; Kidn | 1970 |
[Study of the behavior of uric acid in childhood].
Topics: Age Factors; Child; Child, Preschool; Communicable Diseases; Female; Humans; Infant; Infant, Newborn | 1970 |
[Study of the behavior of uric acid in childhood].
Topics: Age Factors; Child; Child, Preschool; Communicable Diseases; Female; Humans; Infant; Infant, Newborn | 1970 |
[The kidneys and hyperuricemia. Therapeutic problems].
Topics: Gout; Humans; Hypertension; Kidney Diseases; Uric Acid | 1971 |
Urinary concentration, dilution and acid excretion in subjects with a single kidney.
Topics: Adolescent; Adult; Child; Female; Glomerular Filtration Rate; Humans; Hydrogen-Ion Concentration; Ki | 1971 |
Uricosuric action of cholecystographic agents. A possible factor in nephrotoxicity.
Topics: Administration, Oral; Adult; Cholecystography; Contrast Media; Creatinine; Female; Humans; Injection | 1971 |
An unusual form of renal disease associated with gout and hypertension.
Topics: Adolescent; Adult; Aged; Biopsy; Cerebrovascular Disorders; Chromosome Aberrations; Chromosome Disor | 1971 |
Distribution and multiple regression analysis of blood pressure in 10,000 Israeli men.
Topics: Adult; Africa, Northern; Age Factors; Aged; Analysis of Variance; Anxiety; Asia; Blood Pressure; Bod | 1971 |
Hyperuricemia and chronic renal disease.
Topics: Adult; Aged; Alcohol Drinking; Chronic Disease; Creatinine; Diabetes Mellitus; Diuretics; Female; Go | 1971 |
[Gout in young patients].
Topics: Adolescent; Adult; Age Factors; Diabetes Complications; Fatty Liver; Gout; Humans; Hyperlipidemias; | 1971 |
[Renal manifestations of hyperuricemia].
Topics: Gout; Humans; Kidney Diseases; Uric Acid | 1971 |
Uricosuria and x-ray contrast agents.
Topics: Cholecystography; Contrast Media; Humans; Iodipamide; Iopanoic Acid; Ipodate; Kidney; Kidney Disease | 1971 |
[The kidney and hyperuricemia].
Topics: Diuretics; Gout; Humans; Kidney Calculi; Kidney Diseases; Kidney Failure, Chronic; Kidney Function T | 1971 |
[Allopurinol].
Topics: Allopurinol; Gout; Humans; Kidney Diseases; Uric Acid; Xanthine Oxidase | 1967 |
[Ethacrynic acid: research on the mechanism of action and clinical use].
Topics: Adolescent; Adult; Aged; Child; Diabetes Insipidus; Diuresis; Edema; Ethacrynic Acid; Female; Heart | 1968 |
The diagnosis of industrial lead poisoning.
Topics: Adult; Blood Cell Count; Blood Pressure Determination; Environmental Exposure; Hematocrit; Humans; K | 1968 |
Hyperuricemia and urate excretion in chronic renal disease.
Topics: Aminohippuric Acids; Blood Flow Velocity; Chronic Disease; Creatinine; Female; Glomerular Filtration | 1968 |
Etiology and treatment of gout--modern concepts.
Topics: Allopurinol; Colchicine; Crystallization; Diagnosis, Differential; Diet Therapy; Gout; Humans; Indom | 1968 |
The clinical differentiation of lead gout from primary gout.
Topics: Alcohol Drinking; Body Height; Body Weight; Child Behavior Disorders; Diagnosis, Differential; Envir | 1968 |
[Uric acid, hypertension, blood vessels and serum lipids].
Topics: Cardiovascular Diseases; Cholesterol; Diuretics; Humans; Hyperglycemia; Hypertension; Kidney Disease | 1968 |
[Therapy of hyperuricemia with allopurinol].
Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Kidney Diseases; Kidney Function Tests; Male; Method | 1968 |
[Congenital hyperuricemia with neurologic disorders].
Topics: Allopurinol; Guanine; Humans; Hypoxanthines; Intellectual Disability; Kidney Diseases; Metabolism, I | 1968 |
[Value of determination of uric acid in urine in the diagnosis of renal insufficiency].
Topics: Acute Kidney Injury; Chronic Disease; Creatinine; Diagnosis, Differential; Humans; Kidney Diseases; | 1968 |
[Allopurinol: its clinical use].
Topics: Adult; Aged; Allopurinol; Child; Diuretics; Female; Gout; Humans; Kidney Diseases; Kidney Failure, C | 1968 |
[Encephalopathy with disorders of purine metabolism. Familial case].
Topics: Adenosine Triphosphate; Allopurinol; Anemia; Brain Diseases; Carbon Isotopes; Child, Preschool; Eryt | 1968 |
[Value of blood uric acid determination during pregnancy].
Topics: Chlorothiazide; Eclampsia; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Funct | 1968 |
[Blood uric acid in arterial hypertension].
Topics: Humans; Hypertension; Kidney Diseases; Uric Acid | 1968 |
[The analysis of non protein nitrogen in renal azotemia].
Topics: Adult; Amino Acids; Creatine; Creatinine; Female; Glomerulonephritis; Humans; Kidney Diseases; Male; | 1968 |
[Gout in advanced age].
Topics: Age Factors; Aged; Allopurinol; Bone and Bones; Cardiovascular Diseases; Colchicine; Female; Gout; H | 1968 |
[Statistical study of 15000 determinations of uric acid and creatinine. Nephrological and thermal repercussions].
Topics: Adolescent; Adult; Balneology; Creatinine; Female; Humans; Kidney Diseases; Male; Middle Aged; Uric | 1968 |
Saturnine gout--a moonshine malady.
Topics: Alcoholic Beverages; Alcoholism; Gout; Humans; Kidney Diseases; Lead Poisoning; Uric Acid | 1969 |
Differential uric acid excretion in essential and renal hypertension.
Topics: Atrophy; Glomerular Filtration Rate; Humans; Hydronephrosis; Hypertension; Hypertension, Renal; Kidn | 1969 |
[Hyperuricemia in therapy with saluretics].
Topics: Diuretics; Gout; Humans; Kidney Diseases; Uric Acid | 1969 |
Ultrastructural studies in hypertension. IV. Toxemia of pregnancy.
Topics: Biopsy; Blood Urea Nitrogen; Capillaries; Creatinine; Female; Hypertension; Juxtaglomerular Apparatu | 1969 |
[Hyperuricemia in internal diseases].
Topics: Anemia; Cardiovascular Diseases; Gout; Hematologic Diseases; Humans; Hydrochlorothiazide; Kidney Dis | 1969 |
Role of the intestinal tract in the elimination of uric acid.
Topics: Allantoin; Ammonia; Carbon Dioxide; Carbon Isotopes; Digestive System Physiological Phenomena; Feces | 1965 |
The renal excretion of urate in chronic lead nephropathy.
Topics: Adult; Creatine; Female; Gout; Humans; In Vitro Techniques; Kidney Diseases; Kidney Function Tests; | 1965 |
Hyperuricemia, acute gout, renal insufficiency and urate nephrolithiasis due to starvation.
Topics: Blood; Colchicine; Diet, Reducing; Fasting; Gout; Humans; Kidney Calculi; Kidney Diseases; Obesity; | 1965 |
[Results of the determination of blood uric acid during the course of the nephrologic syndromes of pregnancy].
Topics: Adult; Female; Humans; In Vitro Techniques; Kidney Diseases; Pregnancy; Pregnancy Complications; Uri | 1965 |
[Chlorothiazide and uric acid elimination].
Topics: Chlorothiazide; Humans; Injections, Intravenous; Kidney Diseases; Uric Acid | 1963 |
[Secondary gout in renal insufficiency].
Topics: Adult; Blood; Glomerulonephritis; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Fun | 1965 |
[The kidneys in gout. Study of their interaction].
Topics: Adult; Gout; Humans; Kidney Diseases; Male; Uric Acid | 1965 |
Allopurinal and acute uric acid nephropathy.
Topics: Adolescent; Aged; Enzyme Therapy; Humans; Kidney Diseases; Leukemia; Male; Purines; Pyrazoles; Pyrim | 1966 |
Use of allopurinol in preventing hyperuricemia in leukemia and lymphoma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Enzyme Therapy; Female; Gout; Humans; Kidney Disea | 1966 |
Uric acid nephropathy complicating acute leukemia in children. Personal cases, pathogenesis, management and prevention.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Kidney Diseases; Leukemia, Lymphoid; Uric Acid | 1966 |
[Behavior of several enzyme activities (GOT, GPT, aldolase) and uricemia in renal insufficiency].
Topics: Adolescent; Adult; Blood; Clinical Enzyme Tests; Female; Fructose-Bisphosphate Aldolase; Humans; Kid | 1966 |
Evaluation of renal function in the course of acute leukemia in children.
Topics: Blood; Child; Child, Preschool; Humans; Kidney Diseases; Leukemia; Uric Acid; Urine | 1966 |
[Trial treatments of hyperuricemia in patients with chronic renal failure. I. Action of benziodarone].
Topics: Blood; Furans; Gout; Humans; Kidney Diseases; Kidney Failure, Chronic; Uremia; Uric Acid; Vasodilato | 1966 |
Effects of allopurinol on gouty and non-gouty uric acid nephropathy.
Topics: Allopurinol; Blood Urea Nitrogen; Enzyme Therapy; Female; Gout; Humans; Kidney Calculi; Kidney Disea | 1966 |
[Simple chemical methods for the comprehension of kidney function].
Topics: Blood Urea Nitrogen; Creatinine; Diagnosis, Differential; Glomerular Filtration Rate; Humans; Insuli | 1966 |