Page last updated: 2024-10-20

uric acid and Joint Pain

uric acid has been researched along with Joint Pain in 26 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain."8.02Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021)
" PZA dosage was less than 1."6.69[Hyperuricemia and arthralgia during pyrazinamide treatment]. ( Ikeda, N; Ikeda, T; Inoue, T; Kurasawa, T; Nakatani, K; Sato, A; Yoshimatsu, H, 1999)
" Twenty-five patients with acute gout arthritis were randomized into two groups and treated over 5 days: group A, diclofenac 75 mg orally, twice a day; and group B, laser irradiation once a day."5.12Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results. ( Campana, V; Gavotto, A; Moya, M; Palma, J; Simes, J; Soriano, F; Soriano, M; Soriano, R; Spitale, L, 2006)
"To analyse the antinociceptive interaction between quercetin (QUER) and diclofenac (DIC) in experimental arthritic gout-pain."4.02Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats. ( Ángeles-López, GE; Aviles-Herrera, J; Bustamante-Marquina, A; Déciga-Campos, M; González-Trujano, ME; Navarrete-Vázquez, G; Ventura-Martínez, R, 2021)
"A 26-year-old man, who had started treatment for pulmonary tuberculosis, developed polyarthralgia, generalised myalgia, weakness, and elevated uric acid and creatine kinase levels."3.81Drug-induced myopathy in a patient with pulmonary tuberculosis. ( Shah, R; Venkatesan, P, 2015)
" The use of recommended first-line treatment agents for AGA may be limited by adverse events."3.11Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial. ( Dong, X; Huang, JY; Li, XP; Liu, JP; Liu, Y; Shang, YX; Wang, XC; Wei, SF; Xie, ZM, 2022)
" PZA dosage was less than 1."2.69[Hyperuricemia and arthralgia during pyrazinamide treatment]. ( Ikeda, N; Ikeda, T; Inoue, T; Kurasawa, T; Nakatani, K; Sato, A; Yoshimatsu, H, 1999)
"In pSS patients only presenting with joint pain, arthritis patients had higher ESSDAI and system involvements, but lower UA and TG levels compared with OA group (P < 0."1.91Osteoarthritis or arthritis? Toward understanding of primary Sjögren's syndrome patients with arthralgia. ( Gao, R; Pu, J; Tang, J; Wang, X; Wu, Z, 2023)
"Intermittent hand joint pain was also an independent risk factor for worse general health description."1.51Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study. ( Aspelund, T; Eiriksdottir, G; Gudnason, V; Harris, TB; Jonsson, H; Launer, LJ, 2019)
"Acute lymphoblastic leukemia (ALL) is the most common childhood neoplasia and may present with arthralgia and arthritis, with the risk of misdiagnosis and diagnostic delay."1.48Characteristics of children with acute lymphoblastic leukemia presenting with arthropathy. ( Brix, N; Hasle, H; Herlin, T; Rosthøj, S, 2018)
"Gout is a painful inflammatory arthropathy caused by crystallization of monosodium urate within the joints."1.38False-negative dual-energy computed tomography in a patient with acute gout. ( Glazebrook, KN; Ida, CM; Kakar, S; Laurini, JA; Leng, S; Moder, KG, 2012)
"The evaluation of patients with joint pain begins during the medical history and the physical examination, when the differential diagnosis can often be narrowed to a few likely possibilities."1.29A rational approach to the diagnosis of arthritis. ( Litman, K, 1996)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's10 (38.46)29.6817
2010's10 (38.46)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Lan, Z1
Chen, L1
Feng, J1
Xie, Z1
Liu, Z1
Wang, F1
Liu, P1
Yue, X1
Du, L1
Zhao, Y1
Yang, P1
Luo, J1
Zhu, Z1
Hu, X1
Cao, L1
Lu, P1
Sah, R1
Lavine, K1
Kim, B1
Hu, H1
Shang, YX1
Dong, X1
Xie, ZM1
Li, XP1
Wang, XC1
Huang, JY1
Wei, SF1
Liu, Y1
Liu, JP1
Gao, R1
Pu, J1
Wu, Z1
Tang, J1
Wang, X1
Jonsson, H1
Aspelund, T1
Eiriksdottir, G1
Harris, TB1
Launer, LJ1
Gudnason, V1
Ventura-Martínez, R1
Déciga-Campos, M2
Bustamante-Marquina, A1
Ángeles-López, GE1
Aviles-Herrera, J1
González-Trujano, ME1
Navarrete-Vázquez, G1
Brix, N1
Hasle, H1
Rosthøj, S1
Herlin, T1
Hoffmeister, C1
Silva, MA1
Rossato, MF1
Trevisan, G1
Oliveira, SM1
Guerra, GP1
Silva, CR1
Ferreira, J1
Shah, R1
Venkatesan, P1
Neogi, T1
Jansen, TL1
Dalbeth, N3
Fransen, J1
Schumacher, HR3
Berendsen, D1
Brown, M1
Choi, H1
Edwards, NL2
Janssens, HJ1
Lioté, F1
Naden, RP1
Nuki, G1
Ogdie, A1
Perez-Ruiz, F3
Saag, K1
Singh, JA2
Sundy, JS1
Tausche, AK1
Vazquez-Mellado, J1
Vaquez-Mellado, J1
Yarows, SA1
Taylor, WJ3
Scirè, CA1
Carrara, G1
Viroli, C1
Cimmino, MA1
Manara, M1
Govoni, M1
Salaffi, F1
Punzi, L1
Montecucco, C1
Matucci-Cerinic, M1
Minisola, G1
Grainger, R2
Waltrip, RW2
Schlesinger, N2
Evans, R2
Sivera, F2
Diaz-Torne, C2
MacDonald, PA1
McQueen, FM1
Taylor, W1
Edwards, L1
Singh, J1
MacDonald, P1
McQueen, F1
Ogbera, A1
Fasanmade, O1
Kalra, S1
Glazebrook, KN1
Kakar, S1
Ida, CM1
Laurini, JA1
Moder, KG1
Leng, S1
Füessl, HS2
Latorre, CA1
Ohta, H1
Shimizu, M1
López, UG1
Reval, MI1
López-Muñoz, FJ1
Lunam, CA1
Gentle, MJ1
Quiceno, GA1
Cush, JJ1
Kobayashi, K1
Deie, M1
Okuhara, A1
Adachi, N1
Yasumoto, M1
Ochi, M1
Soriano, F1
Campana, V1
Moya, M1
Gavotto, A1
Simes, J1
Soriano, M1
Soriano, R1
Spitale, L1
Palma, J1
Jerome, JT1
Sankaran, B1
Thirumagal, K1
Litman, K1
Inoue, T1
Ikeda, N1
Kurasawa, T1
Sato, A1
Nakatani, K1
Ikeda, T1
Yoshimatsu, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Structured Nurse Led Patient Management Programme to Improve Outcomes in Gout: A Randomized Controlled Trial[NCT03345186]56 participants (Anticipated)Interventional2019-04-01Active, not recruiting
Pragmatic, Randomized, Multicenter, Double-blind, Controlled, Clinical Trial of Prednisolone Versus Colchicine for Acute Gout in Primary Care[NCT05698680]Phase 4314 participants (Anticipated)Interventional2023-01-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for uric acid and Joint Pain

ArticleYear
2015 Gout Classification Criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:10

    Topics: Arthralgia; Europe; Gout; Humans; Synovial Fluid; United States; Uric Acid

2015
Iatrogenic rheumatic syndromes in the elderly.
    Clinics in geriatric medicine, 2005, Volume: 21, Issue:3

    Topics: Aged; Arthralgia; Colchicine; Connective Tissue Diseases; Gout; Gout Suppressants; Humans; Hydroxyme

2005

Trials

3 trials available for uric acid and Joint Pain

ArticleYear
Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial.
    Trials, 2022, May-12, Volume: 23, Issue:1

    Topics: Adult; Arthralgia; Arthritis, Gouty; Double-Blind Method; Drugs, Chinese Herbal; Edema; Humans; Medi

2022
Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.
    Photomedicine and laser surgery, 2006, Volume: 24, Issue:2

    Topics: Animals; Arthralgia; Arthritis, Experimental; Biomarkers; Calcium Pyrophosphate; Diclofenac; Dinopro

2006
[Hyperuricemia and arthralgia during pyrazinamide treatment].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 1999, Volume: 37, Issue:2

    Topics: Antitubercular Agents; Arthralgia; Drug Administration Schedule; Humans; Pyrazinamide; Retrospective

1999

Other Studies

21 other studies available for uric acid and Joint Pain

ArticleYear
Mechanosensitive TRPV4 is required for crystal-induced inflammation.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:12

    Topics: Adult; Animals; Arthralgia; Arthritis; Arthritis, Gouty; Crystal Arthropathies; Gout; Humans; Inflam

2021
Osteoarthritis or arthritis? Toward understanding of primary Sjögren's syndrome patients with arthralgia.
    Journal of orthopaedic surgery and research, 2023, Jan-16, Volume: 18, Issue:1

    Topics: Arthralgia; Humans; Metacarpophalangeal Joint; Osteoarthritis; Sjogren's Syndrome; Uric Acid

2023
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Aged; Aged, 80 and over; Area Under Curve; Arthralgia; Cross-Sectional Studies; Female; Hand Joints;

2019
Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats.
    The Journal of pharmacy and pharmacology, 2021, Sep-07, Volume: 73, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis; Diclofenac; Dis

2021
Characteristics of children with acute lymphoblastic leukemia presenting with arthropathy.
    Clinical rheumatology, 2018, Volume: 37, Issue:9

    Topics: Adolescent; Arthralgia; Child; Child, Preschool; Delayed Diagnosis; Diagnostic Errors; Humans; Infan

2018
Participation of the TRPV1 receptor in the development of acute gout attacks.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:2

    Topics: Acute Disease; Anilides; Animals; Arthralgia; Cinnamates; Disease Models, Animal; Gout; Inflammation

2014
Drug-induced myopathy in a patient with pulmonary tuberculosis.
    BMJ case reports, 2015, Jul-15, Volume: 2015

    Topics: Adult; Antitubercular Agents; Arthralgia; Creatine Kinase; Humans; Male; Muscle Weakness; Muscular D

2015
Development and First Validation of a Disease Activity Score for Gout.
    Arthritis care & research, 2016, Volume: 68, Issue:10

    Topics: Aged; Arthralgia; Disease Progression; Factor Analysis, Statistical; Female; Follow-Up Studies; Gout

2016
Progress in measurement instruments for acute and chronic gout studies.
    The Journal of rheumatology, 2009, Volume: 36, Issue:10

    Topics: Acute Disease; Arthralgia; Chronic Disease; Consensus; Consensus Development Conferences as Topic; D

2009
Outcome domains for studies of acute and chronic gout.
    The Journal of rheumatology, 2009, Volume: 36, Issue:10

    Topics: Acute Disease; Arthralgia; Chronic Disease; Consensus; Disability Evaluation; Gout; Humans; Outcome

2009
Menopausal symptoms and the metabolic syndrome in Nigerian women with type 2 diabetes mellitus.
    Climacteric : the journal of the International Menopause Society, 2011, Volume: 14, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arthralgia; Body Mass Index; Cholesterol, HDL; Cross-Sectional Studi

2011
False-negative dual-energy computed tomography in a patient with acute gout.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:3

    Topics: Allopurinol; Arthralgia; Biopsy; False Negative Reactions; Gout; Gout Suppressants; Humans; Magnetic

2012
[Attack of gout].
    MMW Fortschritte der Medizin, 2012, Jun-11, Volume: 154, Issue:11

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Gouty; Diagnosis, Diffe

2012
Clinical problem solving: too old for this joint!
    Journal of the Mississippi State Medical Association, 2012, Volume: 53, Issue:7

    Topics: Arthralgia; Arthritis, Rheumatoid; Calculi; Diagnosis, Differential; Humans; Knee Joint; Male; Middl

2012
Tophaceous gout.
    Annals of nuclear medicine, 2002, Volume: 16, Issue:6

    Topics: Aged; Arthralgia; Bone Neoplasms; Colonic Neoplasms; Diagnosis, Differential; Gout; Humans; Knee Joi

2002
Enhancement of antinociception by co-administration of an opioid drug (morphine) and a preferential cyclooxygenase-2 inhibitor (rofecoxib) in rats.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arthralgia; Cyclooxygenase 2; Cycloox

2003
Substance P immunoreactive nerve fibres in the domestic chick ankle joint before and after acute urate arthritis.
    Neuroscience letters, 2004, Jan-09, Volume: 354, Issue:2

    Topics: Animals; Arthralgia; Arthritis; Chickens; Disease Models, Animal; Down-Regulation; Female; Gout; Imm

2004
[Diagnosis at a glance: painful awakening].
    MMW Fortschritte der Medizin, 2004, Apr-08, Volume: 146, Issue:15

    Topics: Alcohol Drinking; Arthralgia; Gout; Humans; Male; Metabolic Clearance Rate; Middle Aged; Toe Joint;

2004
Tophaceous gout in the bipartite patella with intra-osseous and intra-articular lesions: a case report.
    Journal of orthopaedic surgery (Hong Kong), 2005, Volume: 13, Issue:2

    Topics: Adult; Arthralgia; Arthritis, Gouty; Arthroscopy; Biopsy, Needle; Follow-Up Studies; Humans; Immunoh

2005
Carpal bone involvement in gout.
    Archives of orthopaedic and trauma surgery, 2007, Volume: 127, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Arthralgia; Carpal Bones; Gout; Humans; Male; Metatarsal Bones; Phy

2007
A rational approach to the diagnosis of arthritis.
    American family physician, 1996, Volume: 53, Issue:4

    Topics: Adult; Aged; Algorithms; Antibodies, Antinuclear; Arthralgia; Arthritis; Biomarkers; Blood Sedimenta

1996