Page last updated: 2024-10-20

uric acid and Ischemic Stroke

uric acid has been researched along with Ischemic Stroke in 33 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.

Research Excerpts

ExcerptRelevanceReference
"The role of serum uric acid as a factor in the recurrence of ischemic stroke stays unclear."9.41Serum Uric Acid Levels and Recurrence Rate of Ischemic Stroke: A Meta-Analysis. ( Gao, Y; Li, M; Wang, H, 2023)
"Serum uric acid (UA) has been suggested to be correlated with outcomes after stroke."9.22Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis. ( Jin, X; Ren, Z; Wang, Y; Wen, Q; Yan, X; Zhang, W, 2022)
"Meta-analysis was performed to assess the value of serum uric acid in the prognosis of ischemic stroke."9.12Association between uric acid and the prognosis of acute ischemic stroke: A systematic review and meta-analysis. ( Ma, A; Pan, X; Wang, K; Wang, Y; Yin, R; Zhang, M, 2021)
"We analyzed 4,621 acute ischemic stroke patients enrolled in the Fukuoka Stroke Registry between June 2007 and September 2019 whose uric acid levels were measured at least twice during hospitalization (including on admission)."8.31Association between decreases in serum uric acid levels and unfavorable outcomes after ischemic stroke: A multicenter hospital-based observational study. ( Ago, T; Irie, F; Kamouchi, M; Kitazono, T; Kiyohara, T; Matsuo, R; Nakamura, K; Ueki, K; Wakisaka, Y, 2023)
"The relationship between serum uric acid (SUA) and poor cognitive performance in patients with ischemic stroke is unclear."8.31The association between serum uric acid and cognitive performance in patients with ischemic stroke is modified by estimated glomerular filtration rate. ( Bai, B; Gao, H; Li, D; Meng, P; Zhang, C; Zhang, X, 2023)
"Evidence on the longitudinal associations between serum uric acid (SUA) and stroke was limited and yielded inconsistent conclusions."8.31Cumulative Serum Uric Acid Exposure and Its Time Course With the Risk of Incident Stroke. ( Chen, S; Luo, Y; Tian, X; Wang, A; Wang, P; Wu, S; Xu, Q; Zhang, X; Zhang, Y, 2023)
" This study aimed to explore the relationship between total bilirubin-to-uric acid ratio (TUR) and sleep quality after acute ischemic stroke (AIS)."8.31High total bilirubin-to-uric acid ratio predicts poor sleep quality after acute ischemic stroke: a prospective nested case-control study. ( Chen, J; Geng, D; He, J; Lin, Y; Liu, Y; Tang, W; Wu, B, 2023)
"Previous studies have found that uric acid (UA) plays a neuroprotective role in ischemic stroke patients."8.12Sex-specific relationship between serum uric acid levels and the prevalence of large vessel occlusion in acute ischemic stroke. ( Li, X; Ma, A; Pan, X; Wei, J; Yin, R, 2022)
" Whereas Serum Uric acid acts as a marker of tissue infarction; indicating poor prognosis of ischemic stroke."8.12A Study on the Role of Serum Calcium, Serum Albumin and Serum Uric Acid as Markers of Initial Neurological Severity and Short Term Outcome Indicators in Acute Ischemic Stroke. ( Bc, PK; Somannavar, VG, 2022)
"The role of uric acid as a risk factor for cerebrovascular disease, particularly acute ischemic stroke, is controversial and there is little information about this in our setting."8.12Relationship of Serum Uric Acid Level with Acute Ischemic Stroke: A Single-Center, Hospital-Based Study from Bangladesh. ( Hossain, MS; Jasmine, T; Kamrul-Hasan, AB; Rahman, MM; Saha, PK; Sarker, MA, 2022)
"Higher serum levels of homocysteine, CRP, and Pro-BNP are associated with a higher risk of acute ischemic stroke."8.12Role of Serum Homocysteine, C-Reactive Protein (CRP), Uric Acid & Pro-Brain Natriuretic Peptide (Pro-BNP) in Predicting the Functional Outcome in Patients with Ischemic Stroke- A Prospective Observational Study from North India. ( Atam, V; Chauhan, H; Reddy, DH; Sawlani, KK, 2022)
"Despite the promising neuroprotective effects of uric acid (UA) in acute ischemic stroke, the seemingly pleiotropic underlying mechanisms are not completely understood."8.02Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke. ( Aliena-Valero, A; Baixauli-Martín, J; Chamorro, Á; Pérez, S; Rius-Pérez, S; Salom, JB; Torregrosa, G, 2021)
"To determine the correlation of uric acid (UA) with hemorrhagic transformation (HT) and poor short-term functional outcomes in anterior circulation acute ischemic stroke (AIS) patients after endovascular thrombectomy (EVT)."7.96Lower uric acid level may be associated with hemorrhagic transformation but not functional outcomes in patients with anterior circulation acute ischemic stroke undergoing endovascular thrombectomy. ( Chen, H; Chen, Z; He, Y; Su, Y; Zhang, Y, 2020)
" Although recent studies have shown that high serum uric acid (UA) levels are associated with cognitive dysfunction and may be a risk factor for PSCI, its impact remains unclear."7.96The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke. ( Chen, W; Chen, Z; Gao, X; Gu, Q; Ling, Y; Liu, J; Liu, S; Lv, X; Sun, J; Wei, D; Zhang, J, 2020)
"The relationship between serum uric acid (SUA) and the risk of ischemic stroke (IS) has been fully elucidated in previous studies."7.96J-shaped relationship between serum uric acid levels and the risk of ischemic stroke in high-risk individuals: A hospital-based observational study. ( Gong, T; Hu, G; Li, J; Liu, D; Wang, C; Wang, Q; Wang, Y, 2020)
"The role of serum uric acid as a predictor of stroke among the general Japanese population remains controversial."7.96Serum uric acid and risk of stroke and its types: the Circulatory Risk in Communities Study (CIRCS). ( Cui, R; Hayama-Terada, M; Imano, H; Iso, H; Kitamura, A; Kiyama, M; Li, J; Muraki, I; Ohira, T; Okada, T; Sankai, T; Tanigawa, T; Umesawa, M; Yamagishi, K, 2020)
"The present study suggests that high serum uric acid concentration is associated with better prognosis in ischemic stroke patients with normal renal function, but not in those with abnormal renal function."7.96Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure. ( Bu, X; Chen, J; Geng, D; Guo, D; He, J; Ju, Z; Peng, H; Peng, Y; Wang, A; Xu, T; Zhang, Y; Zheng, X; Zhong, C; Zhu, Z, 2020)
"Uric acid (UA) is an important endogenous free radical scavenger that has been found to have a neuroprotective effect."5.62Prognostic significance of uric acid change in acute ischemic stroke patients with reperfusion therapy. ( Cui, T; Hao, Z; Wang, A; Wang, C; Wang, L; Wu, B; Yuan, Y; Zhu, Q, 2021)
"Hyperuricemia is independently associated with cardiovascular disease (CVD) and is considered to be one of the major risk factors for CVD."5.56Association of variability in uric acid and future clinical outcomes of patient with coronary artery disease undergoing percutaneous coronary intervention. ( Chan, WL; Charng, MJ; Chen, JW; Chen, SC; Chen, YH; Cheng, HM; Chou, CY; Hsu, PF; Huang, CC; Huang, PH; Huang, SS; Leu, HB; Lim, SS; Lin, SJ; Lin, YJ; Lu, TM; Pan, JP; Sung, SH; Wu, CH; Wu, TC; Yang, YL, 2020)
"Uric acid (UA) is a strong endogenous antioxidant that neutralizes the toxicity of peroxynitrite and other reactive species on the neurovascular unit generated during and after acute brain ischemia."5.41Uric Acid: A Translational Journey in Cerebroprotection That Spanned Preclinical and Human Data. ( Chamorro, A; Chauhan, AK; Leira, EC; Planas, AM, 2023)
"The role of serum uric acid as a factor in the recurrence of ischemic stroke stays unclear."5.41Serum Uric Acid Levels and Recurrence Rate of Ischemic Stroke: A Meta-Analysis. ( Gao, Y; Li, M; Wang, H, 2023)
"Serum uric acid (UA) has been suggested to be correlated with outcomes after stroke."5.22Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis. ( Jin, X; Ren, Z; Wang, Y; Wen, Q; Yan, X; Zhang, W, 2022)
" This study aimed to explore the relationship between total bilirubin-to-uric acid ratio (TUR) and sleep quality after acute ischemic stroke (AIS)."4.31High total bilirubin-to-uric acid ratio predicts poor sleep quality after acute ischemic stroke: a prospective nested case-control study. ( Chen, J; Geng, D; He, J; Lin, Y; Liu, Y; Tang, W; Wu, B, 2023)
"The relationship between serum uric acid (SUA) and poor cognitive performance in patients with ischemic stroke is unclear."4.31The association between serum uric acid and cognitive performance in patients with ischemic stroke is modified by estimated glomerular filtration rate. ( Bai, B; Gao, H; Li, D; Meng, P; Zhang, C; Zhang, X, 2023)
"We analyzed 4,621 acute ischemic stroke patients enrolled in the Fukuoka Stroke Registry between June 2007 and September 2019 whose uric acid levels were measured at least twice during hospitalization (including on admission)."4.31Association between decreases in serum uric acid levels and unfavorable outcomes after ischemic stroke: A multicenter hospital-based observational study. ( Ago, T; Irie, F; Kamouchi, M; Kitazono, T; Kiyohara, T; Matsuo, R; Nakamura, K; Ueki, K; Wakisaka, Y, 2023)
"Evidence on the longitudinal associations between serum uric acid (SUA) and stroke was limited and yielded inconsistent conclusions."4.31Cumulative Serum Uric Acid Exposure and Its Time Course With the Risk of Incident Stroke. ( Chen, S; Luo, Y; Tian, X; Wang, A; Wang, P; Wu, S; Xu, Q; Zhang, X; Zhang, Y, 2023)
"Higher serum levels of homocysteine, CRP, and Pro-BNP are associated with a higher risk of acute ischemic stroke."4.12Role of Serum Homocysteine, C-Reactive Protein (CRP), Uric Acid & Pro-Brain Natriuretic Peptide (Pro-BNP) in Predicting the Functional Outcome in Patients with Ischemic Stroke- A Prospective Observational Study from North India. ( Atam, V; Chauhan, H; Reddy, DH; Sawlani, KK, 2022)
"The role of uric acid as a risk factor for cerebrovascular disease, particularly acute ischemic stroke, is controversial and there is little information about this in our setting."4.12Relationship of Serum Uric Acid Level with Acute Ischemic Stroke: A Single-Center, Hospital-Based Study from Bangladesh. ( Hossain, MS; Jasmine, T; Kamrul-Hasan, AB; Rahman, MM; Saha, PK; Sarker, MA, 2022)
" Whereas Serum Uric acid acts as a marker of tissue infarction; indicating poor prognosis of ischemic stroke."4.12A Study on the Role of Serum Calcium, Serum Albumin and Serum Uric Acid as Markers of Initial Neurological Severity and Short Term Outcome Indicators in Acute Ischemic Stroke. ( Bc, PK; Somannavar, VG, 2022)
"Previous studies have found that uric acid (UA) plays a neuroprotective role in ischemic stroke patients."4.12Sex-specific relationship between serum uric acid levels and the prevalence of large vessel occlusion in acute ischemic stroke. ( Li, X; Ma, A; Pan, X; Wei, J; Yin, R, 2022)
"Serum uric acid levels in patients with acute ischaemic stroke are significantly associated with functional prognosis at discharge, although this relationship is nonlinear."4.02Hyperuricaemia as a prognostic factor for acute ischaemic stroke. ( Cabrera Naranjo, FH; Fabre Pi, O; González Hernández, A; Saavedra Santana, P; Sosa-Henríquez, M, 2021)
"Despite the promising neuroprotective effects of uric acid (UA) in acute ischemic stroke, the seemingly pleiotropic underlying mechanisms are not completely understood."4.02Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke. ( Aliena-Valero, A; Baixauli-Martín, J; Chamorro, Á; Pérez, S; Rius-Pérez, S; Salom, JB; Torregrosa, G, 2021)
"The relationship between serum uric acid (SUA) and the risk of ischemic stroke (IS) has been fully elucidated in previous studies."3.96J-shaped relationship between serum uric acid levels and the risk of ischemic stroke in high-risk individuals: A hospital-based observational study. ( Gong, T; Hu, G; Li, J; Liu, D; Wang, C; Wang, Q; Wang, Y, 2020)
" Although recent studies have shown that high serum uric acid (UA) levels are associated with cognitive dysfunction and may be a risk factor for PSCI, its impact remains unclear."3.96The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke. ( Chen, W; Chen, Z; Gao, X; Gu, Q; Ling, Y; Liu, J; Liu, S; Lv, X; Sun, J; Wei, D; Zhang, J, 2020)
"To determine the correlation of uric acid (UA) with hemorrhagic transformation (HT) and poor short-term functional outcomes in anterior circulation acute ischemic stroke (AIS) patients after endovascular thrombectomy (EVT)."3.96Lower uric acid level may be associated with hemorrhagic transformation but not functional outcomes in patients with anterior circulation acute ischemic stroke undergoing endovascular thrombectomy. ( Chen, H; Chen, Z; He, Y; Su, Y; Zhang, Y, 2020)
"The present study suggests that high serum uric acid concentration is associated with better prognosis in ischemic stroke patients with normal renal function, but not in those with abnormal renal function."3.96Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure. ( Bu, X; Chen, J; Geng, D; Guo, D; He, J; Ju, Z; Peng, H; Peng, Y; Wang, A; Xu, T; Zhang, Y; Zheng, X; Zhong, C; Zhu, Z, 2020)
"The role of serum uric acid as a predictor of stroke among the general Japanese population remains controversial."3.96Serum uric acid and risk of stroke and its types: the Circulatory Risk in Communities Study (CIRCS). ( Cui, R; Hayama-Terada, M; Imano, H; Iso, H; Kitamura, A; Kiyama, M; Li, J; Muraki, I; Ohira, T; Okada, T; Sankai, T; Tanigawa, T; Umesawa, M; Yamagishi, K, 2020)
"To investigate the risk factors for acute ischemic stroke (AIS) in patients with type 2 diabetes mellitus (T2DM) patients."3.30Risk factors for acute ischemic stroke in patients with type 2 diabetes mellitus. ( Li, X; Liu, J; Qu, J, 2023)
"There was no recurrence of seizures in those who defaulted for AED and one patient had a seizure even on AED."1.72Stroke Characteristics as Predictors of New-onset Seizure in Patients with Acute Ischemic Stroke. ( Ajmal, M; Bhat, NK; Dhar, M; Jose, A; Mohan, L; Saxena, Y, 2022)
"Symptomatic intracranial hemorrhage (sICH) was defined as HT accompanied by worsening neurological function."1.72U-Shaped Association Between Serum Uric Acid and Hemorrhagic Transformation After Intravenous Thrombolysis. ( Chen, H; Cheng, Z; Fu, Y; Han, Z; Xia, L; Xu, T; Zhan, Z; Zhang, WY, 2022)
"Uric acid (UA) is an important endogenous free radical scavenger that has been found to have a neuroprotective effect."1.62Prognostic significance of uric acid change in acute ischemic stroke patients with reperfusion therapy. ( Cui, T; Hao, Z; Wang, A; Wang, C; Wang, L; Wu, B; Yuan, Y; Zhu, Q, 2021)
"Hyperuricemia is independently associated with cardiovascular disease (CVD) and is considered to be one of the major risk factors for CVD."1.56Association of variability in uric acid and future clinical outcomes of patient with coronary artery disease undergoing percutaneous coronary intervention. ( Chan, WL; Charng, MJ; Chen, JW; Chen, SC; Chen, YH; Cheng, HM; Chou, CY; Hsu, PF; Huang, CC; Huang, PH; Huang, SS; Leu, HB; Lim, SS; Lin, SJ; Lin, YJ; Lu, TM; Pan, JP; Sung, SH; Wu, CH; Wu, TC; Yang, YL, 2020)
"Hyperuricemia was defined as the serum uric acid level of more than 6 mg/dl."1.56Association between Hyperuricemia and Ischemic Stroke: A Case-Control Study. ( Fatima, T; Iftikhar, S; Qureshi, IH, 2020)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's33 (100.00)2.80

Authors

AuthorsStudies
Zhang, M1
Wang, Y5
Wang, K1
Yin, R2
Pan, X2
Ma, A2
Tian, Y1
Xie, Q1
You, J1
Yang, S1
Zhao, H2
Song, Y1
Wei, J1
Li, X2
Bc, PK1
Somannavar, VG1
Chauhan, H1
Atam, V1
Sawlani, KK1
Reddy, DH1
Yan, X1
Ren, Z1
Wen, Q1
Jin, X1
Zhang, W1
Weisshaar, S1
Litschauer, B1
Reichardt, B1
Gruber, F1
Leitner, S1
Sibinovic, S1
Kossmeier, M1
Wolzt, M1
Rahman, MM2
Kamrul-Hasan, AB1
Jasmine, T1
Hossain, MS1
Saha, PK1
Sarker, MA1
Cheng, Z1
Zhan, Z1
Fu, Y1
Zhang, WY1
Xia, L1
Xu, T3
Chen, H2
Han, Z1
Gong, Y1
Tian, X2
Zhou, Y1
Qin, X1
Meng, X2
Chen, P1
Wang, A4
Zhang, C1
Zhang, X3
Meng, P1
Gao, H1
Bai, B1
Li, D1
Li, M1
Wang, H2
Gao, Y2
Chen, S1
Xu, Q1
Wang, P1
Zhang, Y3
Luo, Y1
Wu, S1
Jose, A1
Dhar, M1
Ajmal, M1
Mohan, L1
Saxena, Y1
Bhat, NK1
Nakamura, K1
Ueki, K1
Matsuo, R1
Kiyohara, T1
Irie, F1
Wakisaka, Y1
Ago, T1
Kamouchi, M1
Kitazono, T1
Dai, Y1
Jiang, Y2
Zhang, L1
Qiu, X1
Gu, H1
Li, Z1
Geng, D2
Wu, B2
Lin, Y1
Chen, J3
Tang, W1
Liu, Y1
He, J2
Leira, EC1
Planas, AM1
Chauhan, AK1
Chamorro, A2
Liu, J2
Qu, J1
Li, J2
Muraki, I1
Imano, H1
Cui, R1
Yamagishi, K1
Umesawa, M1
Hayama-Terada, M1
Ohira, T1
Kiyama, M1
Okada, T1
Sankai, T1
Tanigawa, T1
Kitamura, A1
Iso, H1
Lim, SS1
Yang, YL1
Chen, SC1
Wu, CH1
Huang, SS1
Chan, WL1
Lin, SJ1
Chen, JW1
Chou, CY1
Pan, JP1
Charng, MJ1
Chen, YH1
Wu, TC1
Lu, TM1
Hsu, PF1
Huang, PH1
Cheng, HM1
Huang, CC1
Sung, SH1
Lin, YJ1
Leu, HB1
Yuan, K1
Li, S1
Yang, D1
Xie, Y1
Xia, Y1
Wu, M1
Xu, G1
Liu, X1
Arévalo-Lorido, JC1
Carretero-Gómez, J1
Robles, NR1
Hu, G1
Wang, Q2
Wang, C2
Gong, T1
Liu, D1
Sun, J1
Lv, X1
Gao, X1
Chen, Z2
Wei, D1
Ling, Y1
Zhang, J1
Gu, Q1
Chen, W1
Liu, S1
Serdarevic, N1
Stanciu, AE1
Begic, L1
Uncanin, S1
He, Y1
Su, Y1
Zheng, X1
Zhu, Z1
Peng, Y1
Peng, H1
Zhong, C1
Bu, X1
Guo, D1
Ju, Z1
Fatima, T1
Iftikhar, S1
Qureshi, IH1
Aliena-Valero, A1
Rius-Pérez, S1
Baixauli-Martín, J1
Torregrosa, G1
Pérez, S1
Salom, JB1
Cui, T1
Wang, L1
Zhu, Q1
Yuan, Y1
Hao, Z1
Lu, J1
Yu, W1
He, F1
Liu, W1
Hisatome, I1
Yamamoto, T1
Wang, W1
Cheng, J1
Cabrera Naranjo, FH1
Saavedra Santana, P1
González Hernández, A1
Fabre Pi, O1
Sosa-Henríquez, M1

Reviews

4 reviews available for uric acid and Ischemic Stroke

ArticleYear
Association between uric acid and the prognosis of acute ischemic stroke: A systematic review and meta-analysis.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021, 10-28, Volume: 31, Issue:11

    Topics: Adult; Aged; Biomarkers; Female; Humans; Ischemic Stroke; Male; Middle Aged; Prognosis; Risk Assessm

2021
Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2022, Volume: 54, Issue:5

    Topics: Cognitive Dysfunction; Humans; Ischemic Stroke; Prospective Studies; Stroke; Uric Acid

2022
Serum Uric Acid Levels and Recurrence Rate of Ischemic Stroke: A Meta-Analysis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2023, Volume: 55, Issue:7

    Topics: Brain Ischemia; Case-Control Studies; Humans; Ischemic Stroke; Risk Factors; Stroke; Uric Acid

2023
Uric Acid: A Translational Journey in Cerebroprotection That Spanned Preclinical and Human Data.
    Neurology, 2023, Dec-04, Volume: 101, Issue:23

    Topics: Animals; Brain Ischemia; Female; Humans; Ischemic Stroke; Male; Mice; Microcirculation; Multicenter

2023

Trials

1 trial available for uric acid and Ischemic Stroke

ArticleYear
Risk factors for acute ischemic stroke in patients with type 2 diabetes mellitus.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Di

2023

Other Studies

28 other studies available for uric acid and Ischemic Stroke

ArticleYear
Lower uric acid level may be associated with hemorrhagic transformation after intravenous thrombolysis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:5

    Topics: Brain Ischemia; Humans; Ischemic Stroke; Retrospective Studies; Stroke; Thrombolytic Therapy; Uric A

2022
Sex-specific relationship between serum uric acid levels and the prevalence of large vessel occlusion in acute ischemic stroke.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2022, Feb-17, Volume: 44, Issue:2

    Topics: Brain Ischemia; Female; Humans; Ischemic Stroke; Male; Prevalence; Retrospective Studies; Stroke; Ur

2022
A Study on the Role of Serum Calcium, Serum Albumin and Serum Uric Acid as Markers of Initial Neurological Severity and Short Term Outcome Indicators in Acute Ischemic Stroke.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Aged; Biomarkers; Brain Ischemia; Calcium; Child, Preschool; Cross-Sectional Studies; Female; Humans

2022
Role of Serum Homocysteine, C-Reactive Protein (CRP), Uric Acid & Pro-Brain Natriuretic Peptide (Pro-BNP) in Predicting the Functional Outcome in Patients with Ischemic Stroke- A Prospective Observational Study from North India.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Aged; Biomarkers; Brain Ischemia; C-Reactive Protein; Embolic Stroke; Female; Homocysteine; H

2022
Cardiovascular risk and mortality in patients with hyperuricemia treated with febuxostat or allopurinol: a retrospective nation-wide cohort study in Austria 2014-2017.
    Rheumatology international, 2022, Volume: 42, Issue:9

    Topics: Aged; Allopurinol; Austria; Cardiovascular Diseases; Cohort Studies; Febuxostat; Female; Gout; Gout

2022
Relationship of Serum Uric Acid Level with Acute Ischemic Stroke: A Single-Center, Hospital-Based Study from Bangladesh.
    Mymensingh medical journal : MMJ, 2022, Volume: 31, Issue:3

    Topics: Bangladesh; Brain Ischemia; Cholesterol; Cross-Sectional Studies; Hospitals; Humans; Hypertension; H

2022
U-Shaped Association Between Serum Uric Acid and Hemorrhagic Transformation After Intravenous Thrombolysis.
    Current neurovascular research, 2022, Volume: 19, Issue:2

    Topics: Brain Ischemia; Fibrinolytic Agents; Humans; Intracranial Hemorrhages; Ischemic Stroke; Retrospectiv

2022
Association between serum uric acid to serum creatinine ratio and poor functional outcomes in patients with acute ischemic stroke.
    European journal of neurology, 2022, Volume: 29, Issue:11

    Topics: Creatinine; Humans; Ischemic Stroke; Prognosis; Stroke; Uric Acid

2022
The association between serum uric acid and cognitive performance in patients with ischemic stroke is modified by estimated glomerular filtration rate.
    Scientific reports, 2023, 05-02, Volume: 13, Issue:1

    Topics: Aged; Cognition; Female; Glomerular Filtration Rate; Humans; Ischemic Stroke; Male; Retrospective St

2023
Cumulative Serum Uric Acid Exposure and Its Time Course With the Risk of Incident Stroke.
    Stroke, 2023, Volume: 54, Issue:8

    Topics: China; Humans; Ischemic Stroke; Prospective Studies; Risk Factors; Stroke; Uric Acid

2023
Stroke Characteristics as Predictors of New-onset Seizure in Patients with Acute Ischemic Stroke.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:12

    Topics: Anticonvulsants; Female; Humans; Ischemic Stroke; Male; Middle Aged; Seizures; Stroke; Uric Acid

2022
Association between decreases in serum uric acid levels and unfavorable outcomes after ischemic stroke: A multicenter hospital-based observational study.
    PloS one, 2023, Volume: 18, Issue:6

    Topics: Female; Hospitalization; Hospitals; Humans; Ischemic Stroke; Male; Stroke; Uric Acid

2023
Moderate elevation of serum uric acid levels improves short-term functional outcomes of ischemic stroke in patients with type 2 diabetes mellitus.
    BMC geriatrics, 2023, 07-19, Volume: 23, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Ischemic Stroke; Male; Prognosis; Risk Factors; Str

2023
High total bilirubin-to-uric acid ratio predicts poor sleep quality after acute ischemic stroke: a prospective nested case-control study.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2023, Volume: 23, Issue:6

    Topics: Bilirubin; Biomarkers; Case-Control Studies; Female; Humans; Ischemic Stroke; Prospective Studies; S

2023
Serum uric acid and risk of stroke and its types: the Circulatory Risk in Communities Study (CIRCS).
    Hypertension research : official journal of the Japanese Society of Hypertension, 2020, Volume: 43, Issue:4

    Topics: Female; Hemorrhagic Stroke; Humans; Incidence; Ischemic Stroke; Male; Middle Aged; Risk; Sex Factors

2020
Association of variability in uric acid and future clinical outcomes of patient with coronary artery disease undergoing percutaneous coronary intervention.
    Atherosclerosis, 2020, Volume: 297

    Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Artery Disease; Female; Heart Failure; Humans; Hyperur

2020
Uric acid level and risk of symptomatic intracranial haemorrhage in ischaemic stroke treated with endovascular treatment.
    European journal of neurology, 2020, Volume: 27, Issue:6

    Topics: Brain Ischemia; Endovascular Procedures; Humans; Intracranial Hemorrhages; Ischemic Stroke; Thrombec

2020
Cardiovascular risk assessment after one-year acute ischemic stroke based on uric acid levels and renal dysfunction. A clinical study.
    The International journal of neuroscience, 2021, Volume: 131, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Ischemic Stroke

2021
J-shaped relationship between serum uric acid levels and the risk of ischemic stroke in high-risk individuals: A hospital-based observational study.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Aged; Aged, 80 and over; Beijing; Biomarkers; Cross-Sectional Studies; Female; Humans; Inpatients; I

2020
The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke.
    Neuroscience letters, 2020, 08-24, Volume: 734

    Topics: Aged; Biomarkers; Cognitive Dysfunction; Female; Humans; Ischemic Stroke; Male; Middle Aged; Risk Fa

2020
Serum Uric Acid Concentration in Patients with Cerebrovascular Disease (Ischemic Stroke and Vascular Dementia).
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2020, Volume: 74, Issue:2

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cerebrovascular Disorders; Dementia, Vascular; Humans

2020
Lower uric acid level may be associated with hemorrhagic transformation but not functional outcomes in patients with anterior circulation acute ischemic stroke undergoing endovascular thrombectomy.
    Metabolic brain disease, 2020, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Intracranial Hemorrhages; Is

2020
Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure.
    Neurological research, 2020, Volume: 42, Issue:11

    Topics: Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Biomarkers; Blood Pressure; Blood Pressu

2020
Association between Hyperuricemia and Ischemic Stroke: A Case-Control Study.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:8

    Topics: Brain Ischemia; Case-Control Studies; Humans; Hyperuricemia; Ischemic Stroke; Risk Factors; Stroke;

2020
Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke.
    Molecular neurobiology, 2021, Volume: 58, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Body Weight; Brain Edema; Brain Infarction; Cytokines; Gene Expres

2021
Prognostic significance of uric acid change in acute ischemic stroke patients with reperfusion therapy.
    European journal of neurology, 2021, Volume: 28, Issue:4

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Female; Humans; Ischemic Stroke; Male; Middle Aged; Prognos

2021
Uric acid inhibits HMGB1-TLR4-NF-κB signaling to alleviate oxygen-glucose deprivation/reoxygenation injury of microglia.
    Biochemical and biophysical research communications, 2021, 02-12, Volume: 540

    Topics: Animals; Cell Hypoxia; Cell Line; Cell Survival; Disease Models, Animal; Glucose; HMGB1 Protein; Inf

2021
Hyperuricaemia as a prognostic factor for acute ischaemic stroke.
    Neurologia, 2021, Volume: 36, Issue:4

    Topics: Brain Ischemia; Humans; Hyperuricemia; Ischemic Stroke; Prognosis; Stroke; United States; Uric Acid

2021