Page last updated: 2024-10-20

uric acid and Ischemia

uric acid has been researched along with Ischemia in 60 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" The objects of this study is to estimate and correlate the levels of NGAL (neutrophil gelatinase associated lipocalin), IMA (ischemia modified albumin) and Uric acid in prreclampsia."8.31Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia. ( Bhurer Yadav, B; Kaushik, P; Parasher, N; Singh, NK; Suri, A; Yadav, L, 2023)
"For the first time, this study revealed that atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative injury, inflammation, and apoptosis induced by ovarian ischaemia/reperfusion injury."8.12Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury. ( Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF, 2022)
"Uric acid levels are associated with the degree of leg ischemia in patients with PAD."7.85Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment. ( Hirooka, S; Orita, H; Sotoda, Y; Wakabayashi, I, 2017)
"The aim of this study was to evaluate urinary uric acid (UA) and lipid peroxidation levels, plasma myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and serum UA in neonatal rats subjected to hypoxia-ischemia neonatal HI model."7.77Assessment of uric acid and lipid peroxidation in serum and urine after hypoxia-ischemia neonatal in rats. ( Kaefer, M; Moresco, RN; Moretto, MB; Pimentel, VC; Pinheiro, FV, 2011)
"The aim of this study was to evaluate the effect of allopurinol, methylene blue, and a monoclonal antibody to the adhesion molecule ICAM-1 in intestinal ischemia and reperfusion injury."7.72Effects of the anti-ICAM-1 monoclonal antibody, allopurinol, and methylene blue on intestinal reperfusion injury. ( Alatas, O; çOlak, O; Ilhan, H; Koku, N; Paşaoĝlu, O; Tokar, B, 2003)
"The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries."7.70Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999)
"Allopurinol, a xanthine-oxidase (XO) inhibitor, has been used to improve the resistance to ischemia with disappointing results that have been attributed to administration regimen of the drug."7.68Improved survival in intestinal ischemia by allopurinol not related to xanthine-oxidase inhibition. ( Garcia Garcia, J; Gomez Alonso, A; Holgado Madruga, M; Macias Nuñez, JF; Mariño Hernandez, E; Martin Rollan, C; Refoyo Enrinquez, MA, 1990)
"These studies suggest that tourniquet-induced exsanguination for limb surgery is a significant source for toxic oxygen production in the form of H2O2 and that xanthine oxidase is probably the H2O2-generating enzyme that is formed during the ischemia-reperfusion event."5.08Tourniquet-induced exsanguination in patients requiring lower limb surgery. An ischemia-reperfusion model of oxidant and antioxidant metabolism. ( Barnes, L; Dries, DJ; Mathru, M; Rooney, MW; Sukhani, R; Tonino, P, 1996)
" The objects of this study is to estimate and correlate the levels of NGAL (neutrophil gelatinase associated lipocalin), IMA (ischemia modified albumin) and Uric acid in prreclampsia."4.31Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia. ( Bhurer Yadav, B; Kaushik, P; Parasher, N; Singh, NK; Suri, A; Yadav, L, 2023)
" We hypothesized that asymptomatic HU would attenuate AKD because soluble, in contrast to crystalline, uric acid (sUA) can attenuate sterile inflammation."4.12Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages. ( Anders, HJ; Carangelo, G; De Chiara, L; Gnemmi, V; Li, C; Li, Q; Ma, Q; Molina-Van den Bosch, M; Romagnani, P; Steiger, S, 2022)
"For the first time, this study revealed that atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative injury, inflammation, and apoptosis induced by ovarian ischaemia/reperfusion injury."4.12Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury. ( Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF, 2022)
"Uric acid levels are associated with the degree of leg ischemia in patients with PAD."3.85Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment. ( Hirooka, S; Orita, H; Sotoda, Y; Wakabayashi, I, 2017)
"The aim of this study was to evaluate urinary uric acid (UA) and lipid peroxidation levels, plasma myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and serum UA in neonatal rats subjected to hypoxia-ischemia neonatal HI model."3.77Assessment of uric acid and lipid peroxidation in serum and urine after hypoxia-ischemia neonatal in rats. ( Kaefer, M; Moresco, RN; Moretto, MB; Pimentel, VC; Pinheiro, FV, 2011)
" Levels of uric acid, one of the prototypical "alarm signals," surge after ischemia-reperfusion injury."3.74Ischemia-induced exocytosis of Weibel-Palade bodies mobilizes stem cells. ( Addabbo, F; Cohen-Gould, L; Goligorsky, MS; Kuo, MC; Ni, J; Park, HC; Patschan, D; Patschan, S, 2008)
" Single-dose treatment with UA, as well as acute hyperuricemia induced by the inhibition of uricase, caused a robust mobilization of EPCs, whereas administration of adenosine or inosine seemed to lack this effect."3.74Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells. ( Chintala, S; Gobe, GG; Goligorsky, MS; Patschan, D; Patschan, S, 2007)
"The aim of this study was to evaluate the effect of allopurinol, methylene blue, and a monoclonal antibody to the adhesion molecule ICAM-1 in intestinal ischemia and reperfusion injury."3.72Effects of the anti-ICAM-1 monoclonal antibody, allopurinol, and methylene blue on intestinal reperfusion injury. ( Alatas, O; çOlak, O; Ilhan, H; Koku, N; Paşaoĝlu, O; Tokar, B, 2003)
"The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries."3.70Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999)
"We investigated whether stimulation of bile flow by taurocholic acid (TCA), ursodeoxycholic acid (UDCA) or its taurine conjugate (TUDCA) could protect the liver from ischemia-reperfusion injury."3.68Effect of bile acids on ischemia-reperfusion liver injury. ( Ballet, F; Bonnefis, MT; Chazouillères, O; Chrétien, Y; Legendre, C; Poupon, R; Rey, C, 1991)
"While studying xanthine-xanthine oxidase system it was found, that a considerable accumulation of xanthine and uric acid occurred whereas xanthine dehydrogenase did not transfer in xanthine oxidase during 2 hours of total rat liver ischemia."3.68[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?]. ( Bilenko, MV; Nagler, LG; Oktiabr'skaia, LA; Rashba, IuE; Vartanian, LS, 1990)
"Allopurinol, a xanthine-oxidase (XO) inhibitor, has been used to improve the resistance to ischemia with disappointing results that have been attributed to administration regimen of the drug."3.68Improved survival in intestinal ischemia by allopurinol not related to xanthine-oxidase inhibition. ( Garcia Garcia, J; Gomez Alonso, A; Holgado Madruga, M; Macias Nuñez, JF; Mariño Hernandez, E; Martin Rollan, C; Refoyo Enrinquez, MA, 1990)
" Lung effluent was collected immediately pre- and postischemia for analysis of uric acid by high-pressure liquid chromatography."3.67Xanthine oxidase inhibition attenuates ischemic-reperfusion lung injury. ( Bolling, SF; Deeb, GM; Gallagher, KP; Grum, CM; Lynch, MJ; Morganroth, ML, 1988)
"We describe here a new type of acute renal failure with severe loin pain which develops after anaerobic exercise (ALPE), for example, 200-meter track racing."2.41Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise in patients with or without renal hypouricemia. ( Ishikawa, I, 2002)
"In contrary, the so-called type 2 diabetes is a multifactorial, often hyperinsulinaemic condition of insulin resistance and it occurs mainly in the adults."2.40[From type 2 diabetes to metabolic X syndrome]. ( Pogátsa, G, 1999)
"In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death."2.36Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980)
"KO hearts showed a 41."1.72Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia- reperfusion injury. ( Aponte, A; Cockman, ME; Gucek, M; Harris, M; Keeran, K; Kennedy, LM; Murphy, E; Pirooznia, M; Singh, K; Springer, D; Sun, J, 2022)
"Acute kidney injury is associated with high mortality, especially in intensive care unit patients."1.46Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice. ( Andres-Hernando, A; Chen, W; Cicerchi, C; Fini, M; Inaba, S; Ishimoto, T; Johnson, RJ; Lanaspa, MA; Le, MT; Li, N; Milagres, T; Nakagawa, T; Roncal-Jimenez, C; Wempe, MF, 2017)
"Type V hyperlipemia is not very common."1.26[Type V hyperlipemia. 54 cases (author's transl)]. ( Beaumont, V; Buxtorf, JC; Jacotot, B; Schlesinger, M, 1979)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199018 (30.00)18.7374
1990's13 (21.67)18.2507
2000's17 (28.33)29.6817
2010's6 (10.00)24.3611
2020's6 (10.00)2.80

Authors

AuthorsStudies
Harris, M1
Sun, J2
Keeran, K1
Aponte, A1
Singh, K1
Springer, D1
Gucek, M1
Pirooznia, M1
Cockman, ME1
Murphy, E1
Kennedy, LM1
Gnemmi, V1
Li, Q2
Ma, Q2
De Chiara, L1
Carangelo, G1
Li, C2
Molina-Van den Bosch, M1
Romagnani, P1
Anders, HJ1
Steiger, S1
Afolabi, OA1
Hamed, MA1
Anyogu, DC1
Adeyemi, DH1
Odetayo, AF1
Akhigbe, RE1
Parasher, N1
Kaushik, P1
Singh, NK1
Yadav, L1
Bhurer Yadav, B1
Suri, A1
Sebesta, I1
Miyamoto, D1
Stiburkova, B1
Blahova, S1
Sato, N1
Nagata, K1
Okamoto, K1
Tsuruoka, S1
Ichida, K1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Wang, J4
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J2
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM2
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD2
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Chen, W3
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
Hegde, H1
Shimpi, N1
Panny, A1
Glurich, I1
Christie, P1
Acharya, A1
English, KL1
Downs, M1
Goetchius, E1
Buxton, R1
Ryder, JW1
Ploutz-Snyder, R1
Guilliams, M1
Scott, JM1
Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
Aasen, T1
Gjestad, R1
Nordfalk, KF1
Nordahl, SHG1
Inoue, T1
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
Hood, K1
Johnson, ML1
McArthur, T1
Olson, BA1
Weinstock, RS1
Oser, SM1
Oser, TK1
Bugielski, B1
Strayer, H1
Aleppo, G1
Maruyama, H1
Hirayama, K1
Yamashita, M1
Ohgi, K1
Tsujimoto, R1
Takayasu, M1
Shimohata, H1
Kobayashi, M1
Buscagan, TM1
Rees, DC1
Jaborek, JR1
Zerby, HN1
Wick, MP1
Fluharty, FL1
Moeller, SJ1
Razavi, P1
Dickler, MN1
Shah, PD1
Toy, W1
Brown, DN1
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Li, BT1
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Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Preoperative Intravenous High Dose Methylprednisolone on Endothelial Function in Patients Scheduled for Total Knee-arthroplasty[NCT02332629]Phase 370 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for uric acid and Ischemia

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise in patients with or without renal hypouricemia.
    Nephron, 2002, Volume: 91, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Adult; Exercise; Female; Humans; Ischemia; Kidney; Male; Pain; Tomo

2002
Ischemic-reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy.
    Clinical immunology (Orlando, Fla.), 2008, Volume: 128, Issue:2

    Topics: Animals; Calcium Pyrophosphate; Carrier Proteins; Cytoskeletal Proteins; Humans; Inflammation; Inter

2008
Renal manifestations of extrarenal neoplasms.
    Human pathology, 1980, Volume: 11, Issue:1

    Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm

1980
[From type 2 diabetes to metabolic X syndrome].
    Orvosi hetilap, 1999, Mar-21, Volume: 140, Issue:12

    Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hyperinsulinism; Insulin Resistance; Ischemia; Mal

1999
Uric acid as a risk factor for cardiovascular disease.
    QJM : monthly journal of the Association of Physicians, 2000, Volume: 93, Issue:11

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Female; Humans; Insulin Resistance; Ischemia; Male; Midd

2000
Early manifestations and investigation of cerebral arteriosclerosis.
    The Practitioner, 1976, Volume: 217, Issue:1297

    Topics: Angiography; Basilar Artery; Blood Glucose; Brain; Carotid Artery Diseases; Cerebrovascular Disorder

1976

Trials

4 trials available for uric acid and Ischemia

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
A vasodilating β1 blocker celiprolol inhibits muscular release of uric acid precursor in patients with essential hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2013, Volume: 45, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Blood Pressure; Celiprolol; Exercise Test; Female; For

2013
Tourniquet-induced exsanguination in patients requiring lower limb surgery. An ischemia-reperfusion model of oxidant and antioxidant metabolism.
    Anesthesiology, 1996, Volume: 84, Issue:1

    Topics: Adult; Antioxidants; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Ischemia; Knee J

1996
Laparoscopic surgery-induced changes in oxidative stress markers in human plasma.
    Surgical endoscopy, 2001, Volume: 15, Issue:11

    Topics: Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Cholecystect

2001

Other Studies

50 other studies available for uric acid and Ischemia

ArticleYear
Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia- reperfusion injury.
    Cardiovascular research, 2022, 10-21, Volume: 118, Issue:13

    Topics: Animals; beta-Alanine; Carnosine; Carrier Proteins; Chromatography, Liquid; Infarction; Inosine; Iro

2022
Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages.
    Cells, 2022, 02-11, Volume: 11, Issue:4

    Topics: Acute Kidney Injury; Animals; Humans; Hyperuricemia; Inflammation; Ischemia; Macrophages; Mice; Phen

2022
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury.
    Redox report : communications in free radical research, 2022, Volume: 27, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Atorvastatin; Caspase 3; Down-Regulat

2022
Association of neutrophil gelatinase associated lipocalin, ischemia modified albumin with uric acid in the etiopathogenesis of preeclampsia.
    Hormone molecular biology and clinical investigation, 2023, Mar-01, Volume: 44, Issue:1

    Topics: Acute-Phase Proteins; Biomarkers; Female; Humans; Ischemia; Lipocalin-2; Lipocalins; Pre-Eclampsia;

2023
Modified forearm ischemic test in hypouricemic patients.
    Nucleosides, nucleotides & nucleic acids, 2020, Volume: 39, Issue:10-12

    Topics: Adult; Exercise Test; Female; Forearm; Humans; Hypoxanthine; Ischemia; Lactic Acid; Male; Middle Age

2020
Uric acid enhances alteplase-mediated thrombolysis as an antioxidant.
    Scientific reports, 2018, 10-26, Volume: 8, Issue:1

    Topics: Adult; Animals; Antioxidants; Area Under Curve; Disease Models, Animal; Endothelial Cells; Female; F

2018
Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice.
    Nature communications, 2017, 02-13, Volume: 8

    Topics: Acute Kidney Injury; Aldehyde Reductase; Animals; Cell Line; Fructokinases; Fructose; Humans; Ischem

2017
Association of Serum Uric Acid Levels with Leg Ischemia in Patients with Peripheral Arterial Disease after Treatment.
    Journal of atherosclerosis and thrombosis, 2017, Jul-01, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Biomarkers; Carotid Intima-Media Thickness; Exercise

2017
Ischemia-induced exocytosis of Weibel-Palade bodies mobilizes stem cells.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:12

    Topics: Angiopoietin-2; Cells, Cultured; Exocytosis; Hematopoietic Stem Cells; Humans; Interleukin-8; Ischem

2008
TNF-alpha induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin.
    Basic research in cardiology, 2009, Volume: 104, Issue:1

    Topics: Animals; Antithrombins; Endothelium, Vascular; Exudates and Transudates; Glycocalyx; Guinea Pigs; He

2009
Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase.
    Journal of dermatological science, 2009, Volume: 55, Issue:2

    Topics: Biomarkers; Cell Hypoxia; Cell Line; Cell Survival; Glucose; Glutathione; Glutathione Disulfide; Hum

2009
Molybdenum cofactor deficiency in a Malaysian child.
    Singapore medical journal, 2009, Volume: 50, Issue:10

    Topics: Brain Diseases; Child; Coenzymes; Cysteine; Diagnosis, Differential; Humans; Hypoxanthine; Hypoxia;

2009
Influence on energy kinetics and histology of different preservation solutions seen during cold ischemia in the liver.
    Transplantation proceedings, 2009, Volume: 41, Issue:10

    Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism;

2009
Prevalence and risk factors for renal artery stenosis and chronic kidney disease in Japanese patients with peripheral arterial disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Albuminuria; Angiography; Asian People; Cholesterol, LDL; Como

2010
Assessment of uric acid and lipid peroxidation in serum and urine after hypoxia-ischemia neonatal in rats.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32, Issue:1

    Topics: Albumins; Animals; Animals, Newborn; Disease Models, Animal; Hypoxia; Ischemia; Lipid Peroxidation;

2011
[METABOLIC FUNCTIONS IN SHOCK].
    Minerva medica, 1963, Dec-15, Volume: 54

    Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; Catecholamines; Glucose-6-Phosphatase; Glycogen

1963
Effects of the anti-ICAM-1 monoclonal antibody, allopurinol, and methylene blue on intestinal reperfusion injury.
    Journal of pediatric surgery, 2003, Volume: 38, Issue:11

    Topics: Allopurinol; Animals; Antibodies, Monoclonal; Drug Evaluation, Preclinical; Ileum; Intercellular Adh

2003
Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia.
    Free radical biology & medicine, 2004, Jan-01, Volume: 36, Issue:1

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Hyperoxia; Hypoxia; Ischemia; L-Lactate Dehydro

2004
Components of the metabolic syndrome and risk for first-ever acute ischemic nonembolic stroke in elderly subjects.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Aged; Apolipoprotein A-I; Brain Ischemia; Case-Control Studies; Cholesterol; Cholesterol, HDL; Diabe

2005
[Arterial hypertension in clinical assessment of ischemic renal disease].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Pressure; Cholesterol; Circadian Rhythm; Female; Humans; Hypertension

2005
Alterations in plasma antioxidants during reperfusion of the ischemic small intestine in rats.
    Research in veterinary science, 2006, Volume: 81, Issue:1

    Topics: Animals; Antioxidants; Female; Intestine, Small; Ischemia; Lipid Peroxidation; Oxidative Stress; Per

2006
Recurring exercise-induced acute renal failure with usual daily work.
    Nephrology (Carlton, Vic.), 2007, Volume: 12, Issue:1

    Topics: Acute Kidney Injury; Humans; Ischemia; Kidney; Male; Middle Aged; Pain; Physical Exertion; Recurrenc

2007
Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:5

    Topics: Adenosine; Animals; Cell Movement; Chronic Disease; Endothelial Cells; Hyperuricemia; Inosine; Ische

2007
Analysis of water-soluble antioxidants by high-pressure liquid chromatography.
    The Biochemical journal, 1995, Feb-15, Volume: 306 ( Pt 1)

    Topics: Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Electrochemistry; Glutat

1995
The analysis of metabolites in human sweat: analytical methods and potential application to investigation of pressure ischaemia of soft tissues.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 1)

    Topics: Adult; Chlorides; Colorimetry; Electrolytes; Female; Flame Ionization; Humans; Ischemia; Lactates; L

1994
The value of peritoneal fluid hypoxanthine besides lactic acid in detection of the vascular compromise of intestine.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1993, Volume: 3, Issue:2

    Topics: Animals; Ascitic Fluid; Guinea Pigs; Hypoxanthine; Hypoxanthines; Ileal Diseases; Intestinal Obstruc

1993
Ischemia/reperfusion alters uric acid and ascorbic acid levels in liver.
    The Journal of surgical research, 1996, Jul-15, Volume: 64, Issue:1

    Topics: Animals; Ascorbic Acid; Ischemia; Liver; Liver Circulation; Membranes, Artificial; Microdialysis; Os

1996
Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:3

    Topics: Animals; Arteries; Brain; Capillaries; Constriction; Female; Fetus; Hypoxanthine; Ischemia; Ovary; P

1999
Changes in hepatic microdialysate uric acid levels in porcine liver ischemia/reperfusion.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Animals; Female; Hepatic Artery; Ischemia; Liver; Microdialysis; Portal Vein; Reperfusion; Swine; Ur

2000
[Type V hyperlipemia. 54 cases (author's transl)].
    La Nouvelle presse medicale, 1979, Mar-10, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Aged; Alcoholism; Blood Protein Electrophoresis; Child; Child, Preschool; Cholest

1979
Urid acid accumulated in isolated kidney grafts: an assessment of agonal ischaemia.
    International urology and nephrology, 1979, Volume: 11, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Hypoxanthin

1979
A two-stage enzymatic method for determination of uric acid and hypoxanthine/xanthine.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Volume: 86, Issue:2

    Topics: Humans; Hypoxanthines; Ischemia; Methods; Urate Oxidase; Uric Acid; Xanthine Oxidase; Xanthines

1978
[Level of uric acid in blood serum and its 24-hr. urinary excretion as well as the proportion of these values to total cholesterol level and lipoprotein fraction in sera of patients with chronic ischemia of the extremities].
    Annales Academiae Medicae Stetinensis, 1978, Volume: 24

    Topics: Adult; Aged; Cholesterol; Chronic Disease; Extremities; Female; Humans; Ischemia; Lipoproteins; Male

1978
Protective effect of steroids on liver ischemia.
    The American surgeon, 1975, Volume: 41, Issue:11

    Topics: Adolescent; Adult; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Blood Gluc

1975
Changes in the xanthine dehydrogenase/xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress: preventive effect of some flavonoids.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 78, Issue:2

    Topics: Animals; Free Radical Scavengers; Ischemia; Kidney; Male; Quercetin; Rats; Rats, Wistar; Reperfusion

1992
Uric acid as biochemical marker for retinal and optic nerve damage after occlusion and reperfusion of common carotid and vertebral arteries in rat.
    Japanese journal of ophthalmology, 1992, Volume: 36, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Biomarkers; Carotid Artery Diseases; Chromatography, High Pres

1992
Myogenic hyperuricemia in hypoparathyroidism.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Calcium; Cholecalciferol; Forearm; Glucose; Humans; Hypoparathyroidism; Insulin; Ischemia; Muscles;

1991
Effect of bile acids on ischemia-reperfusion liver injury.
    Journal of hepatology, 1991, Volume: 13, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Bile; Ischemia; Isomerism; L-Lactate Dehydrogenase; Liver Circ

1991
[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 109, Issue:6

    Topics: Animals; Chromatography; Free Radicals; Hypoxanthine; Hypoxanthines; Ischemia; Liver; Rats; Reperfus

1990
Improved survival in intestinal ischemia by allopurinol not related to xanthine-oxidase inhibition.
    The Journal of surgical research, 1990, Volume: 48, Issue:2

    Topics: Allopurinol; Animals; Chromatography, Liquid; Hypoxanthine; Hypoxanthines; Intestines; Ischemia; Oxy

1990
[Acute ischemic optic neuropathy. IV. Biochemical changes in the peripheral blood].
    Klinika oczna, 1988, Volume: 90, Issue:12

    Topics: Acute Disease; Aged; Alpha-Globulins; Female; Humans; Hyperlipidemias; Ischemia; Lipids; Male; Middl

1988
Reduced susceptibility to lipid peroxidation in cold ischemic rabbit kidneys after addition of desferrioxamine, mannitol, or uric acid to the flush solution.
    Cryobiology, 1986, Volume: 23, Issue:4

    Topics: Animals; Deferoxamine; Freezing; Glutathione; Glutathione Disulfide; Ischemia; Kidney; Lipid Peroxid

1986
Xanthine oxidase inhibition attenuates ischemic-reperfusion lung injury.
    The Journal of surgical research, 1988, Volume: 44, Issue:5

    Topics: Animals; Iodine Radioisotopes; Ischemia; Lung; Microscopy, Electron; Oxamic Acid; Regional Blood Flo

1988
Allopurinol and hypoxanthine pretreatment of canine kidney donors.
    Transplantation, 1974, Volume: 17, Issue:4

    Topics: Allopurinol; Animals; Creatinine; Dogs; Drug Therapy, Combination; Graft Rejection; Hypoxanthines; I

1974
[Ischemia tolerance of the kidney with special reference to morphologic and functional findings. (Experimental contribution on kidney preservation)].
    Zeitschrift fur experimentelle Chirurgie, 1974, Volume: 7, Issue:1

    Topics: Animals; Creatinine; Dogs; Ischemia; Kidney; Kidney Function Tests; Kidney Transplantation; Organ Pr

1974
[Aseptic, primary osteonecrosis of the femur head].
    Acta orthopaedica Belgica, 1972, Volume: 38, Issue:5

    Topics: Alcoholism; Femur Head; Femur Head Necrosis; Gout; Humans; Hyperlipidemias; Ischemia; Obesity; Osteo

1972
Selected findings of the Israeli ischemic heart disease study.
    Geriatrics, 1973, Volume: 28, Issue:2

    Topics: Adult; Aged; Blood Glucose; Blood Group Antigens; Blood Pressure; Body Height; Body Weight; Choleste

1973
Responses of the ischemic myocardium to allopurinol.
    American heart journal, 1971, Volume: 82, Issue:3

    Topics: Allopurinol; Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Coronary Disease; Cor

1971
Effect of allopurinol in renal ischemia.
    Surgery, 1972, Volume: 71, Issue:5

    Topics: Allopurinol; Animals; Aspartate Aminotransferases; Autopsy; Blood Urea Nitrogen; Creatinine; Dogs; F

1972
Ischemic cerebrovascular disease. The assessment of risk factors.
    Geriatrics, 1968, Volume: 23, Issue:3

    Topics: Adult; Age Factors; Aged; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D

1968