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uric acid and Inflammatory Bowel Diseases

uric acid has been researched along with Inflammatory Bowel Diseases in 11 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Research Excerpts

ExcerptRelevanceReference
" This study was conducted to investigate inosine, a potent immunomodulator, in 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced chronic model of experimental colitis, and contribution of adenosine A(2A) receptors and the metabolite uric acid as possible underlying mechanisms."7.76Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mohammadi, H; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010)
" This study was conducted to investigate inosine, a potent immunomodulator, in 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced chronic model of experimental colitis, and contribution of adenosine A(2A) receptors and the metabolite uric acid as possible underlying mechanisms."3.76Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mohammadi, H; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010)
" All of the above RCTs showed that probiotics did not increase the incidence of adverse events."2.82Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis: A systematic review and meta-analysis of 34 randomized controlled trials. ( Chen, H; Deng, Y; He, Q; Li, J; Liu, H; Xiang, W; Yang, K; Zeng, L; Zhu, X, 2022)
"Uric acid content was highest when colon surgery had occurred."1.32Urine stone risk factors in nephrolithiasis patients with and without bowel disease. ( Coe, FL; O'Connor, RC; Parks, JH; Worcester, EM, 2003)
" The paradoxical effect observed with probenecid was not seen in the E3040 dose-response curve for the uric acid excretion rate."1.30Mechanism of the uricosuric action of E3040, a drug used to treat inflammatory bowel disease II: study using DBA/2N mice. ( Furitsu, H; Iga, T; Kotaki, H; Sawada, Y; Yamada, H, 1999)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Zeng, L1
Deng, Y1
He, Q1
Yang, K1
Li, J1
Xiang, W1
Liu, H1
Zhu, X1
Chen, H1
Xie, XQ1
Geng, Y1
Guan, Q1
Ren, Y1
Guo, L1
Lv, Q1
Lu, ZM1
Shi, JS1
Xu, ZH1
Rahimian, R1
Fakhfouri, G1
Daneshmand, A1
Mohammadi, H1
Bahremand, A1
Rasouli, MR1
Mousavizadeh, K1
Dehpour, AR1
Parks, JH1
Worcester, EM1
O'Connor, RC1
Coe, FL1
Bairaktari, ET1
Kakafika, AI1
Pritsivelis, N1
Hatzidimou, KG1
Tsianos, EV1
Seferiadis, KI1
Elisaf, MS1
Reynolds, TM1
Buffinton, GD1
Doe, WF1
Yamada, H2
Kotaki, H2
Furitsu, H2
Sawada, Y2
Iga, T2
McLeod, RS1
Churchill, DN1
Fukushima, T1
Yamazaki, Y1
Sugita, A1
Tsuchiya, S1

Reviews

3 reviews available for uric acid and Inflammatory Bowel Diseases

ArticleYear
Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis: A systematic review and meta-analysis of 34 randomized controlled trials.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Arthritis, Rheumatoid; Bone Diseases, Metabolic; Chronic Disease; Dietary Supplements; Gout; Humans;

2022
ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis.
    Journal of clinical pathology, 2005, Volume: 58, Issue:2

    Topics: Acidosis, Renal Tubular; Calcium; Calcium, Dietary; Citrates; Cystinuria; Diet, Protein-Restricted;

2005
Urolithiasis complicating inflammatory bowel disease.
    The Journal of urology, 1992, Volume: 148, Issue:3 Pt 2

    Topics: Humans; Inflammatory Bowel Diseases; Oxalates; Uric Acid; Urinary Calculi

1992

Other Studies

8 other studies available for uric acid and Inflammatory Bowel Diseases

ArticleYear
Influence of Short-Term Consumption of
    Nutrients, 2021, Mar-21, Volume: 13, Issue:3

    Topics: Adult; Alkaline Phosphatase; Bacteria; Biomarkers; Creatinine; Fatty Acids, Volatile; Feces; Female;

2021
Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.
    European journal of pharmacology, 2010, Dec-15, Volume: 649, Issue:1-3

    Topics: Adenosine A2 Receptor Antagonists; Animals; Biomarkers; Colitis; Dietary Supplements; Drug Synergism

2010
Urine stone risk factors in nephrolithiasis patients with and without bowel disease.
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Calcium Oxalate; Calcium Phosphates; Citric Acid; Female; Humans; Hydrogen-Ion Concentration; Inflam

2003
Hypouricemia in individuals admitted to an inpatient hospital-based facility.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:6

    Topics: Blood Glucose; Diabetes Mellitus; Glycosuria; Hematologic Neoplasms; Hospital Departments; Humans; I

2003
Depleted mucosal antioxidant defences in inflammatory bowel disease.
    Free radical biology & medicine, 1995, Volume: 19, Issue:6

    Topics: Antioxidants; Colitis, Ulcerative; Crohn Disease; Free Radical Scavengers; Free Radicals; Glutathion

1995
Mechanism of the uricosuric action of the anti-inflammatory drug E3040 used to treat inflammatory bowel disease I: study using a rat model of hyperuricemia.
    Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:2

    Topics: Animals; Benzothiazoles; Disease Models, Animal; Inflammatory Bowel Diseases; Inulin; Kidney Tubules

1999
Mechanism of the uricosuric action of E3040, a drug used to treat inflammatory bowel disease II: study using DBA/2N mice.
    Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:5

    Topics: Animals; Benzothiazoles; Gastrointestinal Agents; Inflammatory Bowel Diseases; Male; Mice; Mice, Inb

1999
Prophylaxis of uric acid stone in patients with inflammatory bowel disease following extensive colonic resection.
    Gastroenterologia Japonica, 1991, Volume: 26, Issue:4

    Topics: Adult; Bicarbonates; Colectomy; Female; Humans; Hydrogen-Ion Concentration; Incidence; Inflammatory

1991