uric acid has been researched along with Hypoplastic Left Heart Syndrome in 1 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Hypoplastic Left Heart Syndrome: A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this investigation was to determine the pharmacokinetic disposition of intravenous allopurinol and its metabolite oxypurinol in neonates with the hypoplastic left heart syndrome (HLHS) and to evaluate the subsequent degree of xanthine oxidase inhibition using serum uric acid as a marker." | 7.69 | The pharmacokinetics of injectable allopurinol in newborns with the hypoplastic left heart syndrome. ( Clancy, RR; Davis, LE; Jacobs, ML; Krawczeniuk, MM; McGaurn, SP; Murphy, JD; Norwood, WI, 1994) |
| "The purpose of this investigation was to determine the pharmacokinetic disposition of intravenous allopurinol and its metabolite oxypurinol in neonates with the hypoplastic left heart syndrome (HLHS) and to evaluate the subsequent degree of xanthine oxidase inhibition using serum uric acid as a marker." | 3.69 | The pharmacokinetics of injectable allopurinol in newborns with the hypoplastic left heart syndrome. ( Clancy, RR; Davis, LE; Jacobs, ML; Krawczeniuk, MM; McGaurn, SP; Murphy, JD; Norwood, WI, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McGaurn, SP | 1 |
| Davis, LE | 1 |
| Krawczeniuk, MM | 1 |
| Murphy, JD | 1 |
| Jacobs, ML | 1 |
| Norwood, WI | 1 |
| Clancy, RR | 1 |
1 other study available for uric acid and Hypoplastic Left Heart Syndrome
| Article | Year |
|---|---|
The pharmacokinetics of injectable allopurinol in newborns with the hypoplastic left heart syndrome.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; | 1994 |