Page last updated: 2024-10-20

uric acid and Hyponatremia

uric acid has been researched along with Hyponatremia in 85 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Hyponatremia associated with high urinary fractional excretion of uric acid which persists after serum sodium is corrected is the cardinal feature of salt losing nephropathy (SLN)."7.83Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury? ( Johnson, RJ; Lanaspa, MA; Lee, SK; Sánchez-Lozada, LG, 2016)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."7.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"In hyponatremia related to syndrome of inappropriate antidiuretic hormone (SIADH), hypouricemia is explained primarily by the high uric acid clearance rate that results from the decrease in tubular uric acid reabsorption."7.69Evidence in hyponatremia related to inappropriate secretion of ADH that V1 receptor stimulation contributes to the increase in renal uric acid clearance. ( Decaux, G; Gulbis, B; Namias, B; Soupart, A, 1996)
"Hyponatremia, associated with low or high uric acid level is mainly due to severe cation depletion (around 600 mmol) and not due to water retention, since body weight did not change significantly (SNa 122 ± 2."3.88Severe Solute Depletion in Patients with Hyponatremia Due to Diuretics Despite Biochemical Pictures Similar Than Those Observed in the Syndrome of Inappropriate Secretion of Antidiuretic Hormone. ( Decaux, G; Musch, W, 2018)
"Hyponatremia associated with high urinary fractional excretion of uric acid which persists after serum sodium is corrected is the cardinal feature of salt losing nephropathy (SLN)."3.83Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury? ( Johnson, RJ; Lanaspa, MA; Lee, SK; Sánchez-Lozada, LG, 2016)
"The high fractional excretion (FE) of uric acid observed in hyponatremia associated with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is commonly attributed to the volume-expanded state, although volume expansion in normonatremic volunteers is unable to increase urate clearance to a degree similar to that in SIADH."3.70Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion. ( Decaux, G; Musch, W; Prospert, F; Soupart, A, 2000)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."3.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"In hyponatremia related to syndrome of inappropriate antidiuretic hormone (SIADH), hypouricemia is explained primarily by the high uric acid clearance rate that results from the decrease in tubular uric acid reabsorption."3.69Evidence in hyponatremia related to inappropriate secretion of ADH that V1 receptor stimulation contributes to the increase in renal uric acid clearance. ( Decaux, G; Gulbis, B; Namias, B; Soupart, A, 1996)
"Altered uric acid regulation that resembles SIADH is present in patients with polydipsia-hyponatremia syndrome."3.69Hypouricemia in chronic schizophrenic patients with polydipsia and hyponatremia. ( Amagai, I; Hagimoto, H; Hanihara, T; Makimoto, Y, 1997)
"Twenty-eight elderly inpatients with severe hyponatremia were investigated prospectively to determine if fractional uric acid clearance was increased significantly in the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) compared with other causes of hyponatremia."3.67Increased uric acid clearance in the syndrome of inappropriate secretion of antidiuretic hormone. ( Rosin, A; Sonnenblick, M, 1988)
"Hypouricemia seen with hyponatremia related to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) results from an increase in uric acid renal clearance."3.67Mechanisms of hypouricemia in the syndrome of inappropriate secretion of antidiuretic hormone. ( Decaux, G; Dumont, I; Hanson, B; Waterlot, Y, 1985)
"The approach to hyponatremia is in a state of flux, especially in differentiating syndrome of inappropriate antidiuretic hormone secretion (SIADH) from cerebral-renal salt wasting (RSW) because of diametrically opposite therapeutic goals."2.87High Prevalence of Renal Salt Wasting Without Cerebral Disease as Cause of Hyponatremia in General Medical Wards. ( Imbriano, LJ; Maesaka, JK; Miyawaki, N, 2018)
"The etiology of hyponatremia is often multifactorial."2.61Hypovolemic Hyponatremia. ( Greenberg, A; Lehrich, RW; Mohottige, D, 2019)
"On the other hand, inappropriate treatment of hyponatremia (under- or mainly overtreatment) may also lead to devastating consequences."2.53Ten common pitfalls in the evaluation of patients with hyponatremia. ( Christopoulou, F; Elisaf, MS; Filippatos, TD; Liamis, G, 2016)
"Hyponatremia is one of the most common electrolyte disorders encountered in clinical practice."2.46Hyponatremia: evaluation and management. ( Carluccio, AL; Merlin, MA; Zenenberg, RD, 2010)
"Hyponatremia is more frequently observed in elderly patients associated with exaggerated response of ADH release and attenuated response of renin-aldosterone system."2.39SIADH and other hyponatremic disorders: diagnosis and therapeutic problems. ( Saito, T, 1996)
"Hyperkalemia is produced by redistribution of cellular and extracellular potassium or by increased body potassium."2.36Diagnostic strategies in disorders of fluid, electrolyte and acid-base homeostasis. ( Bastl, CP; Jones, ER; Narins, RG; Rudnick, MR; Stom, MC, 1982)
" A comparison of baseline blood metabolites with those obtained after the full Cy dosage (day 0) revealed a significant increase in blood glucose and uric acid levels with an associated decrease in serum calcium, sodium, and potassium levels."1.91Serum Electrolyte and Metabolic Changes During Conditioning of Autologous Hematopoietic Stem Cell Transplantation in Patients with Autoimmune Diseases: A Prospective Study in a Single Institution. ( Gallardo-Pérez, MM; Méndez-Laureano, BJ; Minutti-Zanella, C; Ruiz-Argüelles, GJ, 2023)
"This hyponatremia is saline-responsive, but relapse can be frequently observed."1.51Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
. ( Decaux, G; Musch, W, 2019)
"The diagnosis of SIADH is based on the exclusion of other hyponatremic conditions, the presence of hyposmolality with inappropriate urine osmolality and a urine sodium concentration usually above 30 mEq/L."1.35The syndrome of inappropriate secretion of antidiuretic hormone (SIADH). ( Decaux, G, 2009)
"Aldosterone levels were much lower in ACTH deficiency patients during the hyponatremic state (33 +/- 40 pg/ml) when compared with the nonendocrine SIADH (120 +/- 60 pg/ml; P < 0."1.32Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency. ( Decaux, G; Musch, W; Penninckx, R; Soupart, A, 2003)
"Hyponatremia is seen in 40% to 60% of hospitalized acquired immune deficiency syndrome (AIDS) patients."1.31Normouricemia in the syndrome of inappropriate antidiuretic hormone secretion. ( Akalin, E; Chandrakantan, A; Hamburger, RJ; Keane, J, 2001)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199035 (41.18)18.7374
1990's15 (17.65)18.2507
2000's20 (23.53)29.6817
2010's11 (12.94)24.3611
2020's4 (4.71)2.80

Authors

AuthorsStudies
Bardanzellu, F1
Marcialis, MA1
Frassetto, R1
Melis, A1
Fanos, V1
Méndez-Laureano, BJ1
Gallardo-Pérez, MM1
Minutti-Zanella, C1
Ruiz-Argüelles, GJ1
Mohottige, D1
Lehrich, RW1
Greenberg, A1
Decaux, G13
Gankam Kengne, F1
Assadi, F1
Mazaheri, M1
Musch, W6
Maesaka, JK7
Imbriano, LJ3
Miyawaki, N3
Al Wakeel, JS1
Cheungpasitporn, W1
Erickson, SB1
Rule, AD1
Enders, F1
Lieske, JC1
Filippatos, TD1
Liamis, G3
Christopoulou, F1
Elisaf, MS2
Lee, SK1
Lanaspa, MA1
Sánchez-Lozada, LG1
Johnson, RJ1
Nigro, N1
Winzeler, B1
Suter-Widmer, I1
Schuetz, P1
Arici, B1
Bally, M1
Blum, CA1
Nickel, CH1
Bingisser, R1
Bock, A1
Huber, A1
Müller, B1
Christ-Crain, M1
Mattana, J1
Drakakis, J1
Bitew, S1
Imbriano, L1
Fishbane, S2
Ali, NM1
Ilamathi, E1
Zenenberg, RD1
Carluccio, AL1
Merlin, MA1
FREI, E1
BENTZEL, CJ1
RIESELBACH, R1
BLOCK, JB1
LYON, AF1
DEGRAFF, AC1
Penninckx, R1
Soupart, A5
Frey, FJ1
Kubota, H1
Tanabe, Y1
Takanashi, J1
Kohno, Y1
Gersch, M1
Mutig, K1
Bachmann, S1
Kumar, S1
Ouyang, X1
Johnson, R1
Yamazawa, K1
Kodo, K1
Maeda, J1
Omori, S1
Hida, M1
Mori, T1
Awazu, M1
Palaia, T1
Durham, JH1
Christidis, D1
Alexandridis, G1
Bairaktari, E1
Madias, NE1
Elisaf, M2
Soni, SS1
Adikey, GK1
Raman, AS1
Fenske, W1
Störk, S1
Koschker, AC1
Blechschmidt, A1
Lorenz, D1
Wortmann, S1
Allolio, B1
Passamonte, PM1
Malbran, J1
Agard, D1
Libeskind, M1
Redelsperger, PY1
Lecouillard, C1
Pannetier, C1
Smith, WE1
Steele, TH2
Narins, RG1
Jones, ER1
Stom, MC1
Rudnick, MR1
Bastl, CP1
Ducobu, J1
Dupont, P1
Kamoi, K1
Toyama, M1
Ishibashi, M1
Yamaji, T1
Schlesser, M1
Coffernils, M1
Prospert, F3
Namias, B2
Brimioulle, S1
Crook, M1
Tanneau, RS2
Moal, MC1
Rouhart, F1
Dueymes, JM1
Bourbigot, B1
Gulbis, B1
Saito, T2
Hanihara, T1
Amagai, I1
Hagimoto, H1
Makimoto, Y1
Yamamoto, T1
Fukuyama, J1
Kabayama, Y1
Harada, H1
Akalin, E1
Chandrakantan, A1
Keane, J1
Hamburger, RJ1
Schepkens, H1
Stubbe, J1
Hoeben, H1
Vanholder, R1
Lameire, N1
Milionis, HJ1
Liamis, GL1
Rizos, E1
Saad, W1
Nawar, T1
Kandalaft, N1
Caron, C1
Beck, LH1
Carlier, J1
Rorive, G1
Bovy, P1
Suki, WN1
Uhlich, E1
Rosen, H1
Mach, RS1
Graber, M1
Corish, D1
Cledes, J1
Pennec, YL1
Thomas, CR1
Dodhia, N1
Cauchie, P1
Batuman, V1
Yudd, M1
Salem, M1
Sved, AF1
Venkatesan, J1
Harle, JR1
Boudes, P1
Disdier, P1
Milandre, L1
Mongin, M1
Weiller, PJ1
Sonnenblick, M2
Rosin, A1
Field, MJ1
Lawrence, JR1
Gouyon, JB1
Guignard, JP1
Ebie, N1
Ryan, W1
Harris, J1
Rosin, AJ1
Pupita, F1
Campolucci, G1
Pulido, M1
Belogi, M1
Rotatori, P1
Ansuini, R1
Frausini, G1
Barone, A1
Gaggi, S1
Dumont, I1
Waterlot, Y1
Hanson, B1
Assadi, FK1
John, EG1
Flémale, A1
Cambier, P1
Puschett, JB1
Burmeister, H1
Ohlmeier, H1
Baethke, R1
Jahnecke, J1
Curtis, J1
Horrigan, F1
Ahearn, D1
Varney, R1
Sandler, SG1
Ben-Ishay, D1
Levy, M1
Birnbaum, D1
Martinez-Maldonado, M1
DeFronzo, RA1
Colvin, OM1
Braine, H1
Robertson, GL1
Davis, PJ1
Anderton, JL1
Kincaid-Smith, P1
Palomaki, JF1
Lindheimer, MD1
Lawlor, T1
Wells, DG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status at the Access in the Emergency Department and at the Subsequent Re-evaluation in Hospital Wards[NCT04402190]123 participants (Actual)Observational2018-06-01Completed
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987]122 participants (Actual)Observational2019-07-30Completed
[NCT00541944]120 participants (Anticipated)Observational2007-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for uric acid and Hyponatremia

ArticleYear
Differential diagnosis between syndrome of inappropriate antidiuretic hormone secretion and cerebral/renal salt wasting syndrome in children over 1 year: proposal for a simple algorithm.
    Pediatric nephrology (Berlin, Germany), 2022, Volume: 37, Issue:7

    Topics: Algorithms; Child; Diagnosis, Differential; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappr

2022
Hypovolemic Hyponatremia.
    Frontiers of hormone research, 2019, Volume: 52

    Topics: Humans; Hyponatremia; Hypovolemia; Uric Acid

2019
Hypertonic saline, isotonic saline, water restriction, long loops diuretics, urea or vaptans to treat hyponatremia.
    Expert review of endocrinology & metabolism, 2020, Volume: 15, Issue:3

    Topics: Acute Disease; Antidiuretic Hormone Receptor Antagonists; Bicarbonates; Chronic Disease; Drinking; H

2020
Ten common pitfalls in the evaluation of patients with hyponatremia.
    European journal of internal medicine, 2016, Volume: 29

    Topics: Diagnosis, Differential; Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; So

2016
Is it cerebral or renal salt wasting?
    Kidney international, 2009, Volume: 76, Issue:9

    Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Brain; Diagnosis, Differential; Extracellular Fluid;

2009
Hyponatremia: evaluation and management.
    Hospital practice (1995), 2010, Volume: 38, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Blood Urea Nitrogen;

2010
RENAL COMPLICATIONS OF NEOPLASTIC DISEASE.
    Journal of chronic diseases, 1963, Volume: 16

    Topics: Antineoplastic Agents; Bence Jones Protein; Hemorrhage; Humans; Hypercalcemia; Hypokalemia; Hyponatr

1963
Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:4

    Topics: Acid-Base Equilibrium; Bicarbonates; Biomarkers; Clinical Laboratory Techniques; Creatinine; Diagnos

2008
Diagnostic strategies in disorders of fluid, electrolyte and acid-base homeostasis.
    The American journal of medicine, 1982, Volume: 72, Issue:3

    Topics: Acid-Base Imbalance; Acidosis; Alkalosis; Bicarbonates; Calcium Metabolism Disorders; Humans; Hyperk

1982
An expanded view of SIADH, hyponatremia and hypouricemia.
    Clinical nephrology, 1996, Volume: 46, Issue:2

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Sodium; Uric Acid

1996
SIADH and other hyponatremic disorders: diagnosis and therapeutic problems.
    Nihon Jinzo Gakkai shi, 1996, Volume: 38, Issue:10

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Diagnosis, Differential; Humans; Hyponatrem

1996
The hyponatremic patient: a systematic approach to laboratory diagnosis.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Apr-16, Volume: 166, Issue:8

    Topics: Acidosis; Algorithms; Blood Gas Analysis; Clinical Laboratory Techniques; Diagnosis, Differential; H

2002
Renal involvement in leukemia and lymphoma.
    Perspectives in nephrology and hypertension, 1976, Volume: 3

    Topics: Amyloidosis; Blood Vessels; Diabetes Insipidus; Humans; Hypercalcemia; Hyponatremia; Kidney; Kidney

1976
Common emergencies in cancer medicine: metabolic syndromes.
    Journal of the National Medical Association, 1991, Volume: 83, Issue:9

    Topics: Acidosis, Lactic; Acute Kidney Injury; Adrenal Cortex Diseases; Emergencies; Humans; Hypercalcemia;

1991
Complications of thiazide diuretic therapy: an update.
    The Medical journal of Australia, 1986, Jun-09, Volume: 144, Issue:12

    Topics: Alkalosis; Benzothiadiazines; Blood Volume; Coronary Disease; Death, Sudden; Diuretics; Drug Hyperse

1986
Diuretics. II. Clinical considerations.
    Drugs, 1971, Volume: 1, Issue:2

    Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I

1971

Trials

3 trials available for uric acid and Hyponatremia

ArticleYear
High Prevalence of Renal Salt Wasting Without Cerebral Disease as Cause of Hyponatremia in General Medical Wards.
    The American journal of the medical sciences, 2018, Volume: 356, Issue:1

    Topics: Aged; Aged, 80 and over; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged

2018
Short-Term Tolvaptan Increases Water Intake and Effectively Decreases Urinary Calcium Oxalate, Calcium Phosphate and Uric Acid Supersaturations.
    The Journal of urology, 2016, Volume: 195, Issue:5

    Topics: Adolescent; Adult; Aged; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Biomarkers; Calciu

2016
Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985.
    The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Diuresis; Humans; Hyponatremia; Ina

2001

Other Studies

66 other studies available for uric acid and Hyponatremia

ArticleYear
Serum Electrolyte and Metabolic Changes During Conditioning of Autologous Hematopoietic Stem Cell Transplantation in Patients with Autoimmune Diseases: A Prospective Study in a Single Institution.
    Hematology/oncology and stem cell therapy, 2023, Jul-20, Volume: 17, Issue:1

    Topics: Adult; Aged; Autoimmune Diseases; Blood Glucose; Creatinine; Cyclophosphamide; Hematopoietic Stem Ce

2023
Differentiating syndrome of inappropriate ADH, reset osmostat, cerebral/renal salt wasting using fractional urate excretion.
    Journal of pediatric endocrinology & metabolism : JPEM, 2021, Jan-27, Volume: 34, Issue:1

    Topics: Adult; Cerebrum; Diagnosis, Differential; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2021
Severe Solute Depletion in Patients with Hyponatremia Due to Diuretics Despite Biochemical Pictures Similar Than Those Observed in the Syndrome of Inappropriate Secretion of Antidiuretic Hormone.
    Nephron, 2018, Volume: 140, Issue:1

    Topics: Aged; Aged, 80 and over; Body Water; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Synd

2018
Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
.
    Clinical nephrology, 2019, Volume: 91, Issue:6

    Topics: Aged; Aged, 80 and over; Calcium; Diuresis; Diuretics; Female; Fluid Therapy; Humans; Hyponatremia;

2019
Kidney function and metabolic profile of chronic kidney disease and hemodialysis patients during Ramadan fasting.
    Iranian journal of kidney diseases, 2014, Volume: 8, Issue:4

    Topics: Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Erythrocyte Count; Fastin

2014
Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?
    Kidney & blood pressure research, 2016, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Female; Fructose; Humans; Hyponatremia; Kidney Diseases; Kidney Tubu

2016
Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: 'The Co-MED Study'.
    Clinical endocrinology, 2017, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Glycopeptides; Hospitalization; Humans; Hydrocorti

2017
Identifying Different Causes of Hyponatremia With Fractional Excretion of Uric Acid.
    The American journal of the medical sciences, 2016, Volume: 352, Issue:4

    Topics: Aged; Aged, 80 and over; Algorithms; Diagnosis, Differential; Female; Humans; Hyponatremia; Inapprop

2016
More on renal salt wasting without cerebral disease: response to saline infusion.
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Aldosterone; Biomarkers; Blood Volume; Diagnosis, Differential; Female; Hum

2009
The syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
    Seminars in nephrology, 2009, Volume: 29, Issue:3

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Sodium; Uric Acid

2009
DIURETIC THERAPY. VI. METABOLIC COMPLICATIONS OF THIAZIDE THERAPY AND THEIR CORRECTION.
    American heart journal, 1964, Volume: 68

    Topics: Bendroflumethiazide; Blood; Blood Urea Nitrogen; Diuretics; Humans; Hydrochlorothiazide; Hyperglycem

1964
Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Aldosterone; Bicarbonates; Carbon Dioxide; Dia

2003
[Serum concentration of uric acid, a diagnostic 'must' in patients with hyponatremia].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:9

    Topics: Blood Volume; Diagnosis, Differential; Extracellular Fluid; Female; Fluid Therapy; Glomerular Filtra

2004
Episodic hyponatremia in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS).
    Journal of child neurology, 2005, Volume: 20, Issue:2

    Topics: Adolescent; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Diagnostic Techniques, Endocri

2005
Is salt-wasting the long awaited answer to the hyperuricaemia seen in uromodulin storage diseases?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Animals; Humans; Hyperuricemia; Hyponatremia; Kidney; Kidney Diseases; Mice; Mice, Knockout; Mucopro

2006
Hyponatremia, hypophosphatemia, and hypouricemia in a girl with macrophage activation syndrome.
    Pediatrics, 2006, Volume: 118, Issue:6

    Topics: Female; Humans; Hyponatremia; Hypophosphatemia; Infant; Macrophage Activation; Metabolic Diseases; S

2006
Renal salt wasting without cerebral disease: diagnostic value of urate determinations in hyponatremia.
    Kidney international, 2007, Volume: 71, Issue:8

    Topics: Aged; Female; Hip Fractures; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidney; Uric Acid

2007
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2007, Volume: 55, Issue:1

    Topics: Aged; Creatinine; Diagnosis, Differential; Diuretics; Edema; Female; Humans; Hyponatremia; Hypovolem

2007
Fractional excretion of uric acid as a therapeutic monitor in cerebral salt wasting syndrome.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2008, Volume: 19, Issue:1

    Topics: Aged; Biomarkers; Brain Diseases; Humans; Hyponatremia; Male; Stroke; Uric Acid; Wasting Syndrome

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Hypouricemia, inappropriate secretion of antidiuretic hormone, and small cell carcinoma of the lung.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Carcinoma, Small Cell; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lung Neoplasms; Mal

1984
[Syndrome of inappropriate antidiuretic hormone secretion. A report of two cases with hyponatremia and hypouricemia].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Sep-23, Volume: 58, Issue:34

    Topics: Apudoma; Carcinoma, Small Cell; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Midd

1982
Avoiding diuretic-related complications in older patients.
    Geriatrics, 1983, Volume: 38, Issue:2

    Topics: Aged; Blood Volume; Diuretics; Glucose; Humans; Hypokalemia; Hyponatremia; Uric Acid

1983
[Hypouricaemia in the syndrome of inappropriate ADH secretion (SIADH) (author's transl)].
    La Nouvelle presse medicale, 1982, Mar-13, Volume: 11, Issue:12

    Topics: Diagnosis, Differential; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Retrospecti

1982
Hyponatremia and osmoregulation of vasopressin secretion in patients with intracranial bleeding.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:10

    Topics: Aged; Aged, 80 and over; Arginine Vasopressin; Blood Pressure; Blood Urea Nitrogen; Cerebral Hemorrh

1995
Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia.
    Clinical nephrology, 1994, Volume: 42, Issue:2

    Topics: Acid-Base Equilibrium; Diuretics; Heart Failure; Humans; Hyponatremia; Hypopituitarism; Inappropriat

1994
Hyponatraemia and hypouricaemia.
    Annals of clinical biochemistry, 1993, Volume: 30 ( Pt 2)

    Topics: Female; Humans; Hyponatremia; Male; Reference Values; Retrospective Studies; Uric Acid

1993
Hypouricemia with high urate clearance in hyponatremia: is it always a clue for increased effective volemia?
    Clinical nephrology, 1995, Volume: 44, Issue:2

    Topics: Aged; Humans; Hyponatremia; Sodium; Uric Acid

1995
Evidence in hyponatremia related to inappropriate secretion of ADH that V1 receptor stimulation contributes to the increase in renal uric acid clearance.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:5

    Topics: Adult; Body Water; Deamino Arginine Vasopressin; Diabetes Insipidus; Humans; Hyponatremia; Inappropr

1996
Hypouricemia in chronic schizophrenic patients with polydipsia and hyponatremia.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:6

    Topics: Adult; Drinking; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Osmolar Concen

1997
Dual facets of hyponatraemia and arginine vasopressin in patients with ACTH deficiency.
    Clinical endocrinology, 1998, Volume: 49, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Arginine Vasopressin; Female; Fluid Therapy; Glucocorticoi

1998
Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Glomerular Filtration Rate; Humans; Hyponatremia

2000
Normouricemia in the syndrome of inappropriate antidiuretic hormone secretion.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Ethambutol; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lu

2001
Utility and limitations of biochemical parameters in the evaluation of hyponatremia in the elderly.
    International urology and nephrology, 2001, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Isot

2001
Severe hyponatraemia and hypouricaemia in Gitelman's syndrome.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:11

    Topics: Adult; Bartter Syndrome; Humans; Hyponatremia; Male; Middle Aged; Uric Acid

2001
Multiple metabolic abnormalities in a patient with the syndrome of inappropriate antidiuresis.
    Nephron, 2002, Volume: 91, Issue:2

    Topics: Blood Volume; Female; Humans; Hypokalemia; Hyponatremia; Inappropriate ADH Syndrome; Magnesium; Midd

2002
[Inappropriate secretion of antidiuretic hormone reversed by administration of declomycin (DMC)].
    L'union medicale du Canada, 1977, Volume: 106, Issue:12

    Topics: Carcinoma, Small Cell; Demeclocycline; Humans; Hyponatremia; Lung Neoplasms; Male; Middle Aged; Para

1977
Hypouricemia in the syndrome of inappropriate secretion of antidiuretic hormone.
    The New England journal of medicine, 1979, Sep-06, Volume: 301, Issue:10

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidney; Retrospective Studies; Uric Acid

1979
Hypouricemia.
    The New England journal of medicine, 1979, Sep-06, Volume: 301, Issue:10

    Topics: Body Water; Diuretics; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidney; Uric Acid

1979
[Diuretics in cardiac insufficiency].
    Acta clinica Belgica, 1977, Volume: 32, Issue:3

    Topics: Alkalosis; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diuretics; Diuretics, Osmotic; Heart Fa

1977
[The syndrome of inappropriate secretion of vasopressin (SIADH) (author's transl)].
    Klinische Wochenschrift, 1977, Apr-01, Volume: 55, Issue:7

    Topics: Diuresis; Hormones; Hormones, Ectopic; Humans; Hyponatremia; Osmolar Concentration; Potassium; Syndr

1977
Renal disease in the elderly.
    The Medical clinics of North America, 1976, Volume: 60, Issue:6

    Topics: Acute Kidney Injury; Aged; Calcium; Chronic Disease; Female; Humans; Hyponatremia; Kidney Calculi; K

1976
[Editorial: Edema from diuretics abuse].
    Schweizerische medizinische Wochenschrift, 1976, Feb-07, Volume: 106, Issue:6

    Topics: Adult; Diuretics; Edema; Female; Humans; Hyperaldosteronism; Hyperglycemia; Hypokalemia; Hyponatremi

1976
[Clinical aspects of hyponatremia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Sep-10, Volume: 80, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Central Nervous System Diseases; Child; Child, Preschool

1991
The electrolytes in hyponatremia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:5

    Topics: Adaptation, Physiological; Animals; Atrial Natriuretic Factor; Bicarbonates; Extracellular Space; Hu

1991
The finding among AIDS patients of paradoxical hypouricemia in the presence of volume depletion combined with hyponatremia and high fractional excretion of sodium.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Aged; Humans; Hyponatremia; Natriuresis; Sodium; Syndrome; Uric

1991
Dissociation between uric acid and urea clearances in the syndrome of inappropriate secretion of antidiuretic hormone related to salt excretion.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:5

    Topics: Adult; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Aged; Osmolar Concentration; Prospec

1990
Hyponatremia and hypouricemia: differentiation from SIADH.
    Clinical nephrology, 1990, Volume: 33, Issue:4

    Topics: Adult; Diagnosis, Differential; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidney; Male; Midd

1990
[Hyponatremia with hypouricemia in corticotropin deficiency].
    Presse medicale (Paris, France : 1983), 1989, Mar-25, Volume: 18, Issue:12

    Topics: Adrenocorticotropic Hormone; Aged; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; M

1989
Increased uric acid clearance in the syndrome of inappropriate secretion of antidiuretic hormone.
    Israel journal of medical sciences, 1988, Volume: 24, Issue:1

    Topics: Aged; Humans; Hyponatremia; Inappropriate ADH Syndrome; Uric Acid

1988
[Kidney function and water-electrolyte balance in the newborn infant].
    Archives francaises de pediatrie, 1987, Volume: 44, Issue:1

    Topics: Acetylglucosaminidase; Acid-Base Equilibrium; beta 2-Microglobulin; Glomerular Filtration Rate; Huma

1987
Metabolic emergencies in cancer medicine.
    The Medical clinics of North America, 1986, Volume: 70, Issue:5

    Topics: Acidosis; ACTH Syndrome, Ectopic; Adrenal Insufficiency; Diagnosis, Differential; Emergencies; Human

1986
Significance of the measurement of uric acid fractional clearance in diuretic induced hyponatraemia.
    Postgraduate medical journal, 1986, Volume: 62, Issue:728

    Topics: Aged; Benzothiadiazines; Diuretics; Furosemide; Humans; Hyponatremia; Sodium Chloride Symporter Inhi

1986
[Negative effects of diuretics].
    La Clinica terapeutica, 1985, Oct-15, Volume: 115, Issue:1

    Topics: Alkalosis; Diuretics; Heart Diseases; Humans; Hyperglycemia; Hypokalemia; Hyponatremia; Insulin; Liv

1985
Mechanisms of hypouricemia in the syndrome of inappropriate secretion of antidiuretic hormone.
    Nephron, 1985, Volume: 39, Issue:3

    Topics: Glomerular Filtration Rate; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidney; Middle Aged; N

1985
Hypouricemia in neonates with syndrome of inappropriate secretion of antidiuretic hormone.
    Pediatric research, 1985, Volume: 19, Issue:5

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Infant, Newborn; Uric Acid

1985
[Significance of the measurement of blood uric acid in the diagnosis of inappropriate antidiuretic hormone secretion syndrome].
    Revue medicale de Liege, 1985, Apr-01, Volume: 40, Issue:7

    Topics: Aged; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Meningitis; Meningitis, Aseptic; Uric

1985
Diuretic therapy update.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Diet, Sodium-Restricted; Diuretics; Ear Diseases; Heart Fa

1985
[Side effects and complication possibilities following high-dosage furosemide treatment].
    Medizinische Klinik, 1972, Oct-27, Volume: 67, Issue:43

    Topics: Adult; Aged; Alkalosis; Blood Coagulation Disorders; Blood Glucose; Dehydration; Drug Eruptions; Ear

1972
[Side effects of antihypertensive agents].
    Medizinische Klinik, 1970, Dec-11, Volume: 65, Issue:50

    Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Diarrhea; Diuretics; Fatigue; Ganglionic Blockers; Ga

1970
Chlorthalidone-induced hyperosmolar hyperglycemic nonketotic coma.
    JAMA, 1972, Jun-19, Volume: 220, Issue:12

    Topics: Adult; Chlorthalidone; Dehydration; Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis; Humans;

1972
Self-induced secondary hyperaldosteronism simulating Bartter's syndrome.
    Israel journal of medical sciences, 1972, Volume: 8, Issue:11

    Topics: Adult; Alkalosis; Diagnosis, Differential; Female; Furosemide; Humans; Hyperaldosteronism; Hypertrop

1972
Electrolyte disturbances resulting from diuretic therapy.
    Texas medicine, 1973, Volume: 69, Issue:7

    Topics: Acetazolamide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Hypokalemia; Hyponatre

1973
Proceedings: Cyclophosphamide and the kidney.
    Cancer, 1974, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Body Weight; Calcium; Cyclophosphamide; Cystitis; Diuresis; Female;

1974
Sodium depletion simulating deterioration in a toxemic pregnancy.
    The New England journal of medicine, 1970, Jan-08, Volume: 282, Issue:2

    Topics: Adult; Diagnosis, Differential; Diet; Diet, Sodium-Restricted; Female; Glomerular Filtration Rate; H

1970
Metabolic hazards of fasting.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:8

    Topics: Adult; Anemia; Autoanalysis; Blood Cell Count; Blood Proteins; Blood Urea Nitrogen; Body Weight; Chl

1969