uric acid has been researched along with Hypokalemia in 90 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred seventy-one patients, 60 years of age or older with isolated systolic hypertension, were randomly assigned to receive chlorthalidone 12." | 9.06 | Isolated systolic hypertension in the elderly. A placebo-controlled, dose-response evaluation of chlorthalidone. ( Aranda, J; Barra, P; Davidov, M; Ettinger, B; Gorwit, J; McBarron, F; Morledge, JH, 1986) |
| " On arrival, laboratory test results were significant for hypokalemia, hyperchloremic metabolic acidosis, low uric acid concentration, positive urine anion gap, and proteinuria, which resolved on discontinuation of the drug." | 7.85 | Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report. ( Afridi, F; Kar, P; King-Morris, K; Komarla, A; Perrone, D, 2017) |
| "A Thai female patient developed muscular weakness, hypouricemia, hypokalemia and hyperchloremic metabolic acidosis after taking outdated tetracycline." | 7.69 | Hypouricemia, hypokalemia, proximal and distal tubular acidification defect following administration of outdated tetracycline: a case report. ( Chusil, S; Pansin, P; Tungsanga, K; Wathanavaha, A, 1994) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 6.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| "One hundred seventy-one patients, 60 years of age or older with isolated systolic hypertension, were randomly assigned to receive chlorthalidone 12." | 5.06 | Isolated systolic hypertension in the elderly. A placebo-controlled, dose-response evaluation of chlorthalidone. ( Aranda, J; Barra, P; Davidov, M; Ettinger, B; Gorwit, J; McBarron, F; Morledge, JH, 1986) |
| "Men and women with isolated systolic hypertension who were at least 60 years of age were treated for 1 year with chlorthalidone (25-50 mg daily) or matching placebo as the step I drug." | 5.06 | Use of diuretics in treatment of hypertension in the elderly. ( Feigal, DW; Furberg, CD; Greenlick, M; Kuller, L; Perry, HM; Schnaper, HW; Schoenberger, JA; Smith, WM, 1986) |
| " On arrival, laboratory test results were significant for hypokalemia, hyperchloremic metabolic acidosis, low uric acid concentration, positive urine anion gap, and proteinuria, which resolved on discontinuation of the drug." | 3.85 | Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report. ( Afridi, F; Kar, P; King-Morris, K; Komarla, A; Perrone, D, 2017) |
| "Trichlormethiazide, a thiazide diuretic, was introduced in 1960 and remains one of the most frequently used diuretics for treating hypertension in Japan." | 3.77 | Adverse effect profile of trichlormethiazide: a retrospective observational study. ( Asai, S; Nakayama, T; Nishida, Y; Takahashi, Y, 2011) |
| " Potassium supplementation improves their insulin resistance and hypertension, whereas allopurinol reduces serum levels of uric acid and ameliorates hypertension, hypertriglyceridemia, hyperglycemia, and insulin resistance." | 3.74 | Thiazide diuretics exacerbate fructose-induced metabolic syndrome. ( Johnson, RJ; Mu, W; Nakagawa, T; Reungjui, S; Roncal, CA; Sirivongs, D; Srinivas, TR, 2007) |
| "A Thai female patient developed muscular weakness, hypouricemia, hypokalemia and hyperchloremic metabolic acidosis after taking outdated tetracycline." | 3.69 | Hypouricemia, hypokalemia, proximal and distal tubular acidification defect following administration of outdated tetracycline: a case report. ( Chusil, S; Pansin, P; Tungsanga, K; Wathanavaha, A, 1994) |
| "Interstitial nephritis consequent to rifampin was associated with potassium wasting, an acidifying defect, high fractional uric acid excretion, and glucosuria, indicating a multiplicity of renal tubular transport abnormalities." | 3.67 | Potassium wasting and other renal tubular defects with rifampin nephrotoxicity. ( Cheng, JT; Kahn, T, 1984) |
| "Indapamide is a useful antihypertensive agent with good patient tolerance in mild or moderate hypertension and may offer advantages over traditional diuretics in view of its possible vasodilator and calcium-antagonist properties, once-a-day dosage, and good therapeutic effect with prolonged usage." | 2.65 | Clinical efficacy and safety of indapamide in essential hypertension. ( Morledge, JH, 1983) |
| "Diuretics have long been used in the treatment of hypertension and are outstandingly efficacious when used either alone or in combination with other antihypertensive compounds." | 2.38 | Diuretics in hypertension: clinical experiences. ( Papademetriou, V, 1992) |
| " This increased potency and the consequent decreased dose requirement give bumetanide the potential for increased effectiveness and decreased incidence of adverse effects." | 2.37 | Cellular mechanism of action of loop diuretics: implications for drug effectiveness and adverse effects. ( Feig, PU, 1986) |
| "In patients with cancer, tumor bulk and invasion of vital organs do not always explain the clinical deterioration and cause of death." | 2.36 | Renal manifestations of extrarenal neoplasms. ( Pascal, RR, 1980) |
| "Individuals with cancer are subject to fluid and electrolyte imbalances because of the original disease process, therapy, and complications resulting from both the disease process and from therapy." | 2.36 | Fluid and electrolyte disturbances associated with cancer and its treatment. ( Cunningham, SG, 1982) |
| "Hyperkalemia is produced by redistribution of cellular and extracellular potassium or by increased body potassium." | 2.36 | Diagnostic strategies in disorders of fluid, electrolyte and acid-base homeostasis. ( Bastl, CP; Jones, ER; Narins, RG; Rudnick, MR; Stom, MC, 1982) |
| "Primary distal renal tubular acidosis (dRTA) is an inherited disease characterized by the inability of the distal tubule to lower urine pH <5." | 1.35 | Atypical presentation of distal renal tubular acidosis in two siblings. ( Blau, N; Cheong, HI; Gucev, Z; Hoppe, B; Korneti, P; Tasic, V, 2008) |
| "In two patients with Bartter's syndrome proximal tubular function and distal chloride reabsorption were intact on admission; however, chloride reabsorption and distal tubular acidifying capacity decreased in one patient over a period of 10 years." | 1.29 | Ammonium urate nephrolithiasis in a variant of Bartter's syndrome with intact renal tubular function. ( Ishii, M; Maio, A; Shioniri, H; Umemura, S; Yasuda, G; Zierer, R, 1994) |
| " Nevertheless, in view of the potential seriousness of volume depletion, dosage should probably begin at 20 rather than 40 mg daily." | 1.26 | Adverse reactions to frusemide in hospital inpatients. ( Gray, J; Henry, DA; Lawson, DH; Lowe, J, 1979) |
| " Their long term use alone provides smooth control of blood pressure in mild to moderate hypertensives (Beevers, Hamilton and Harpur, 1971), and they are also valuable as adjuvant therapy with other antihypertensive drugs." | 1.26 | The effect of thiazide diuretics on coronary risk factors. ( Beevers, DG; Bloxham, CA, 1979) |
| "Uric acid was increased 38 and 48% over the control values by doses of 4." | 1.25 | Nephrotoxicity of dietary ochratoxin A in broiler chickens. ( Hamilton, PB; Huff, WE; Wyatt, RD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 76 (84.44) | 18.7374 |
| 1990's | 6 (6.67) | 18.2507 |
| 2000's | 6 (6.67) | 29.6817 |
| 2010's | 2 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perrone, D | 1 |
| Afridi, F | 1 |
| King-Morris, K | 1 |
| Komarla, A | 1 |
| Kar, P | 1 |
| Takahashi, Y | 1 |
| Nishida, Y | 1 |
| Nakayama, T | 1 |
| Asai, S | 1 |
| WILSON, CP | 1 |
| DAVISON, KS | 1 |
| FREI, E | 1 |
| BENTZEL, CJ | 1 |
| RIESELBACH, R | 1 |
| BLOCK, JB | 1 |
| BODA, D | 1 |
| LYON, AF | 1 |
| DEGRAFF, AC | 2 |
| SPERBER, RJ | 1 |
| FISCH, S | 1 |
| FREUDENTHAL, RR | 1 |
| MAVROMATIS, F | 1 |
| Reungjui, S | 1 |
| Roncal, CA | 1 |
| Mu, W | 1 |
| Srinivas, TR | 1 |
| Sirivongs, D | 1 |
| Johnson, RJ | 1 |
| Nakagawa, T | 1 |
| Tasic, V | 1 |
| Korneti, P | 1 |
| Gucev, Z | 1 |
| Hoppe, B | 1 |
| Blau, N | 1 |
| Cheong, HI | 1 |
| Losse, H | 2 |
| Kayser, D | 1 |
| Morledge, JH | 2 |
| Kojima, S | 1 |
| Ito, K | 1 |
| Ikeda, M | 1 |
| Pascal, RR | 1 |
| Cheng, JT | 1 |
| Kahn, T | 1 |
| Ogilvie, RI | 1 |
| Cunningham, SG | 1 |
| Smith, WE | 1 |
| Steele, TH | 1 |
| Zumkley, H | 1 |
| Quante, T | 1 |
| Perry, HM | 2 |
| Narins, RG | 1 |
| Jones, ER | 1 |
| Stom, MC | 1 |
| Rudnick, MR | 1 |
| Bastl, CP | 1 |
| Holzgreve, H | 1 |
| Morgan, T | 1 |
| Myers, J | 1 |
| Dupont, P | 1 |
| Ducobu, J | 1 |
| Schreiber, S | 1 |
| Lombardo, JV | 1 |
| Terlinsky, A | 1 |
| Chester, AC | 1 |
| Preuss, HG | 1 |
| Shapiro, AP | 1 |
| Traub, YM | 1 |
| Chusil, S | 1 |
| Tungsanga, K | 1 |
| Wathanavaha, A | 1 |
| Pansin, P | 1 |
| Tomino, Y | 1 |
| Mizoguchi, M | 1 |
| Yasuda, G | 1 |
| Zierer, R | 1 |
| Maio, A | 1 |
| Shioniri, H | 1 |
| Ishii, M | 1 |
| Umemura, S | 1 |
| Donati-Genet, P | 1 |
| Donati, R | 1 |
| Colombo, JP | 1 |
| Lüthy, CM | 1 |
| Bianchetti, MG | 1 |
| Liamis, G | 2 |
| Elisaf, M | 2 |
| Palamarchuk, MI | 1 |
| Kozlovskaia, LV | 1 |
| Balkarov, IM | 1 |
| Carducci, MA | 1 |
| Gilbert, J | 1 |
| Bowling, MK | 1 |
| Noe, D | 1 |
| Eisenberger, MA | 1 |
| Sinibaldi, V | 1 |
| Zabelina, Y | 1 |
| Chen, TL | 1 |
| Grochow, LB | 1 |
| Donehower, RC | 1 |
| Rizos, E | 1 |
| Finnerty, FA | 1 |
| Knochel, JP | 2 |
| Carter, NW | 1 |
| Lowe, J | 1 |
| Gray, J | 1 |
| Henry, DA | 1 |
| Lawson, DH | 1 |
| Bloxham, CA | 1 |
| Beevers, DG | 2 |
| Carlier, J | 1 |
| Rorive, G | 1 |
| Bovy, P | 1 |
| Cannon, ML | 1 |
| Tannenbaum, RP | 1 |
| La Franco, M | 1 |
| Hollifield, JW | 1 |
| Bogusky, RT | 1 |
| Lowenstein, LM | 1 |
| Lowenstein, JM | 1 |
| Hirschel, B | 1 |
| Huff, WE | 1 |
| Wyatt, RD | 1 |
| Hamilton, PB | 1 |
| Mach, RS | 1 |
| Glezer, GA | 1 |
| Papademetriou, V | 1 |
| Moser, M | 4 |
| Feig, PU | 1 |
| Ettinger, B | 1 |
| Aranda, J | 1 |
| McBarron, F | 1 |
| Barra, P | 1 |
| Gorwit, J | 1 |
| Davidov, M | 1 |
| Black, H | 1 |
| Stair, D | 1 |
| Field, MJ | 1 |
| Lawrence, JR | 1 |
| Smith, WM | 1 |
| Feigal, DW | 1 |
| Furberg, CD | 1 |
| Greenlick, M | 1 |
| Kuller, L | 1 |
| Schnaper, HW | 1 |
| Schoenberger, JA | 1 |
| Pupita, F | 1 |
| Campolucci, G | 1 |
| Pulido, M | 1 |
| Belogi, M | 1 |
| Rotatori, P | 1 |
| Ansuini, R | 1 |
| Frausini, G | 1 |
| Barone, A | 1 |
| Gaggi, S | 1 |
| Puschett, JB | 1 |
| Chrysant, SG | 1 |
| Frohlich, ED | 1 |
| Jelliffe, RW | 1 |
| Hill, D | 1 |
| Tatter, D | 1 |
| Lewis, E | 1 |
| Förster, H | 1 |
| Heller, L | 1 |
| Hellmund, U | 1 |
| Burmeister, H | 1 |
| Ohlmeier, H | 1 |
| Baethke, R | 1 |
| Pentikäinen, P | 1 |
| Jahnecke, J | 1 |
| Furukawa, T | 1 |
| Kirkendall, WM | 1 |
| Azer, M | 1 |
| Munro, JF | 1 |
| Duncan, LJ | 1 |
| Kramer, HJ | 1 |
| Krück, F | 1 |
| MacFarlane, JP | 1 |
| Kennedy, RD | 1 |
| Ben-Ishay, D | 1 |
| Levy, M | 1 |
| Birnbaum, D | 1 |
| Burgess, JL | 1 |
| Birchall, R | 2 |
| Martinez-Maldonado, M | 1 |
| Dustan, HR | 1 |
| Tarazi, RC | 1 |
| Bravo, EL | 1 |
| Freis, ED | 1 |
| Miyahara, M | 1 |
| Fujise, Y | 1 |
| Hoshikawa, K | 1 |
| Nakagawa, K | 1 |
| Leiter, L | 1 |
| Anderton, JL | 1 |
| Kincaid-Smith, P | 1 |
| Burges, JL | 1 |
| Jachuck, SJ | 1 |
| Antcliff, AC | 1 |
| Hamilton, M | 1 |
| Harpur, JE | 1 |
| Muggia, FM | 1 |
| Heinemann, HO | 1 |
| Farhangi, M | 1 |
| Osserman, EF | 1 |
| Werning, C | 1 |
| Siegenthaler, W | 1 |
| Lant, AF | 1 |
| Wilson, GM | 1 |
| Rastogi, SP | 1 |
| Volans, G | 1 |
| Elliott, RW | 1 |
| Eccleston, DW | 1 |
| Ashcroft, R | 1 |
| Webster, D | 1 |
| Kerr, DN | 1 |
| Berlind, S | 1 |
| Lundvall, O | 1 |
| Shear, L | 1 |
| Bonkowsky, HL | 1 |
| Gabuzda, GJ | 1 |
| Lawlor, T | 1 |
| Wells, DG | 1 |
| Remenchik, AP | 1 |
| Johnston, LC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Uric Acid and Hypertension in African Americans[NCT00241839] | Phase 3 | 150 participants (Actual) | Interventional | 2005-08-31 | Completed | ||
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987] | 122 participants (Actual) | Observational | 2019-07-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The Diastolic BP was taken at Baseline and after 8-10 weeks of treatment or placebo while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol / placebo
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | 3.44 |
| B (Placebo) | -0.83 |
Subjects had 24 hr blood pressure monitoring (ABPM) at baseline and treatment end. The readings were averaged and the changes from baseline to treatment end were compared. (NCT00241839)
Timeframe: Baseline and end of treatment (8-10 weeks on allopurinol / placebo)
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | -5.9 |
| B (Placebo) | 0.90 |
"The systolic BP was taken at Baseline and after 8-10 weeks of treatment on placebo, while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol or placebo
| Intervention | mm Hg (Mean) |
|---|---|
| A (Allopurinol) | 0.21 |
| B (Placebo) | -0.95 |
Subjects on allopurinol are expected to lower their uric acid levels relative to placebo. (NCT00241839)
Timeframe: Baseline UA levels compared to end of treatment levels (8-10 weeks on allopurinol / placebo)
| Intervention | mg/dl (Mean) |
|---|---|
| A (Allopurinol) | 2.29 |
| B (Placebo) | 0.14 |
21 reviews available for uric acid and Hypokalemia
| Article | Year |
|---|---|
RENAL COMPLICATIONS OF NEOPLASTIC DISEASE.
Topics: Antineoplastic Agents; Bence Jones Protein; Hemorrhage; Humans; Hypercalcemia; Hypokalemia; Hyponatr | 1963 |
[Mild hypertension and the role of diuretics].
Topics: Diuretics; Drug Evaluation; Humans; Hypertension; Hypokalemia; Uric Acid | 1984 |
Renal manifestations of extrarenal neoplasms.
Topics: Amyloidosis; Antineoplastic Agents; Disseminated Intravascular Coagulation; Humans; Hypokalemia; Imm | 1980 |
Fluid and electrolyte disturbances associated with cancer and its treatment.
Topics: Blood Volume; Body Water; Calcium; Humans; Hypercalcemia; Hyperkalemia; Hypocalcemia; Hypokalemia; I | 1982 |
Diagnostic strategies in disorders of fluid, electrolyte and acid-base homeostasis.
Topics: Acid-Base Imbalance; Acidosis; Alkalosis; Bicarbonates; Calcium Metabolism Disorders; Humans; Hyperk | 1982 |
[Kidney diseases caused by hypercalcemia, hyperuricemia, hyperoxaluria and hypokalemia].
Topics: Humans; Hypercalcemia; Hyperoxaluria; Hypokalemia; Kidney; Kidney Diseases; Uric Acid | 1994 |
Renal injury in mu.
Topics: Acute Kidney Injury; Adult; Animals; Glomerular Filtration Rate; Hemodynamics; Humans; Hypokalemia; | 1976 |
Diuretics in hypertension: clinical experiences.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypokalemia; Risk F | 1992 |
Cellular mechanism of action of loop diuretics: implications for drug effectiveness and adverse effects.
Topics: Animals; Chlorides; Diuretics; Dose-Response Relationship, Drug; Drug Resistance; Erythrocyte Membra | 1986 |
The dilemma of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypo | 1986 |
Complications of thiazide diuretic therapy: an update.
Topics: Alkalosis; Benzothiadiazines; Blood Volume; Coronary Disease; Death, Sudden; Diuretics; Drug Hyperse | 1986 |
The diuretic dilemma and the management of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Cholesterol; Diuretics; Humans; Hypertension; Hypokalemia; Uric | 1986 |
The diuretic dilemma and the management of mild hypertension.
Topics: Arrhythmias, Cardiac; Decision Making; Diuretics; Drug Therapy, Combination; Glucose; Humans; Hypert | 1986 |
[Metabolic effects of diuretics].
Topics: Angiotensin II; Depression, Chemical; Diuretics; Glucose; Gout; Humans; Hypokalemia; Magnesium; Pota | 1974 |
Diuretics and hypertension.
Topics: Azides; Benzothiadiazines; Blood Vessels; Diuretics; Extracellular Space; Humans; Hyperglycemia; Hyp | 1972 |
Fasting in the treatment of obesity.
Topics: Adolescent; Body Weight; Diet, Reducing; Fasting; Hospitalization; Humans; Hypokalemia; Middle Aged; | 1972 |
[Pharmacological bases of diuretic therapy. 2].
Topics: Acidosis; Alkalosis; Digitalis Glycosides; Diuretics; Drug Synergism; Edema; Gastrointestinal Hemorr | 1974 |
Antihypertensive action of benzothiadiazines.
Topics: Benzothiadiazines; Chlorothiazide; Guanethidine; Humans; Hyperglycemia; Hypertension; Hypokalemia; M | 1968 |
[Effects and side-effects of hypotensive diuretics].
Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Diabetes Mellitus; Diuretics; Gout; Huma | 1968 |
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
Diuretics. II. Clinical considerations.
Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I | 1971 |
12 trials available for uric acid and Hypokalemia
| Article | Year |
|---|---|
[Short and long term treatment of cardiac edemas with ethacrynic acid].
Topics: Adult; Aged; Blood Pressure; Diuresis; Ethacrynic Acid; Female; Heart Failure; Humans; Hypokalemia; | 1967 |
Clinical efficacy and safety of indapamide in essential hypertension.
Topics: Adult; Aged; Animals; Clinical Trials as Topic; Diuretics; Double-Blind Method; Electrolytes; Humans | 1983 |
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.
Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolenc | 2001 |
In defense of traditional antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 1988 |
Isolated systolic hypertension in the elderly. A placebo-controlled, dose-response evaluation of chlorthalidone.
Topics: Age Factors; Aged; Blood Glucose; Body Weight; Chlorthalidone; Cholesterol; Clinical Trials as Topic | 1986 |
The dilemma of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypo | 1986 |
Use of diuretics in treatment of hypertension in the elderly.
Topics: Aged; Chlorthalidone; Creatinine; Double-Blind Method; Female; Humans; Hypertension; Hypokalemia; Ma | 1986 |
[Metabolic investigations during continuous infusion of glucose, fructose, and xylitol over 48 hours (author's transl)].
Topics: Adult; Aspartate Aminotransferases; Clinical Enzyme Tests; Fatty Acids; Fructose; Glucose; Humans; H | 1974 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascu | 1972 |
The effects of amiloride during diuretic therapy in elderly subjects.
Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinatio | 1972 |
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels.
Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans; | 1972 |
Long-term therapy of diabetes insipidus with oral benzothiadiazine and phthalimidine diuretics.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Benzothiadiazines; Blood Glucose; Child; Diabe | 1971 |
58 other studies available for uric acid and Hypokalemia
| Article | Year |
|---|---|
Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report.
Topics: Acidosis; Acidosis, Renal Tubular; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriat | 2017 |
Adverse effect profile of trichlormethiazide: a retrospective observational study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Biomarkers; Blood Urea Nitrogen; Chi-Square Distri | 2011 |
Thiazide hypopotassemia and hyperuricemia.
Topics: Chlorothiazide; Humans; Hyperuricemia; Hypokalemia; Potassium; Thiazides; Uric Acid | 1961 |
[DISEASES OF THE INTRACELLULAR SYSTEM IN THE COURSE OF ACUTE METABOLIC DISTURBANCES].
Topics: Blood Chemical Analysis; Cell Biology; Hypernatremia; Hypokalemia; Metabolic Diseases; Nitrogen; Sep | 1964 |
DIURETIC THERAPY. VI. METABOLIC COMPLICATIONS OF THIAZIDE THERAPY AND THEIR CORRECTION.
Topics: Bendroflumethiazide; Blood; Blood Urea Nitrogen; Diuretics; Humans; Hydrochlorothiazide; Hyperglycem | 1964 |
CORRECTION OF DIURETIC-INDUCED HYPOKALEMIA AND HYPERURICEMIA.
Topics: Bicarbonates; Blood Chemical Analysis; Chlorthalidone; Diuretics; Drug Therapy; Geriatrics; Hydrochl | 1965 |
TETRACYCLINE NEPHROPATHY; CASE REPORT WITH RENAL BIOPSY.
Topics: Acidosis; Acidosis, Renal Tubular; Ataxia; Biopsy; Blood; Chemistry, Pharmaceutical; Glycosuria; Gly | 1965 |
Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
Topics: Allopurinol; Animals; Blood Pressure; Body Weight; Diuretics; Fructose; Gout Suppressants; Hydrochlo | 2007 |
Atypical presentation of distal renal tubular acidosis in two siblings.
Topics: Acidosis, Renal Tubular; Child, Preschool; Chlorides; Growth Disorders; Hearing Loss, Sensorineural; | 2008 |
[Saluresis in the treatment of hypertension].
Topics: Carbohydrate Metabolism; Diet, Sodium-Restricted; Diuretics; Humans; Hypertension; Hypokalemia; Pota | 1966 |
Potassium wasting and other renal tubular defects with rifampin nephrotoxicity.
Topics: Adult; Anti-Bacterial Agents; Humans; Hypokalemia; Kidney Tubules; Male; Nephritis, Interstitial; Po | 1984 |
Diuretic treatment in essential hypertension.
Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Diuretics; Dose-Response Relationship, Drug; Hemodynamics | 1983 |
Avoiding diuretic-related complications in older patients.
Topics: Aged; Blood Volume; Diuretics; Glucose; Humans; Hypokalemia; Hyponatremia; Uric Acid | 1983 |
Side effects of diuretics.
Topics: Calcium; Carbohydrate Metabolism; Diuretics; Drug Interactions; Humans; Hypokalemia; Lipid Metabolis | 1983 |
Some wrong-way chemical changes during antihypertensive treatment: comparison of indapamide and related agents.
Topics: Adult; Antihypertensive Agents; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Humans; Hy | 1983 |
[Therapy of cardiac insufficiency with diuretics].
Topics: Amiloride; Benzothiadiazines; Blood Glucose; Diuretics; Drug Administration Schedule; Female; Furose | 1982 |
The use of diuretics in hypertension.
Topics: Benzothiadiazines; Carbohydrate Metabolism; Diuretics; Dose-Response Relationship, Drug; Humans; Hyp | 1982 |
[Long-term side-effects of diuretics in the treatment of hypertension (author's transl)].
Topics: Blood Glucose; Diuretics; Humans; Hypertension; Hypokalemia; Potassium; Retrospective Studies; Trigl | 1981 |
Tubulointerstitial diseases.
Topics: Analgesics; Drug Hypersensitivity; Glomerular Filtration Rate; Humans; Hypercalcemia; Hypokalemia; I | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydr | 1981 |
Hypouricemia, hypokalemia, proximal and distal tubular acidification defect following administration of outdated tetracycline: a case report.
Topics: Acidosis, Renal Tubular; Adult; Female; Humans; Hypokalemia; Tetracycline; Uric Acid | 1994 |
Ammonium urate nephrolithiasis in a variant of Bartter's syndrome with intact renal tubular function.
Topics: Adult; Bartter Syndrome; Chlorides; Female; Humans; Hypokalemia; Kidney Calculi; Kidney Function Tes | 1994 |
Urinary sodium, potassium, chloride, calcium, magnesium, phosphate, urate and urea in healthy subjects aged 5-18 years.
Topics: Acidosis, Renal Tubular; Adolescent; Calcium; Child; Child, Preschool; Chlorides; Electrolytes; Fema | 1998 |
Hypokalemia, hypophosphatemia and hypouricemia due to proximal renal tubular dysfunction in acute myeloid leukemia.
Topics: Acute Disease; Aged; Female; Humans; Hypokalemia; Hypophosphatemia; Kidney Tubules, Proximal; Leukem | 2000 |
[Bartter's syndrome with hyperuricemia].
Topics: Adult; Aldosterone; Bartter Syndrome; Child; Female; Humans; Hypokalemia; Kidney Failure, Chronic; P | 2001 |
Multiple metabolic abnormalities in a patient with the syndrome of inappropriate antidiuresis.
Topics: Blood Volume; Female; Humans; Hypokalemia; Hyponatremia; Inappropriate ADH Syndrome; Magnesium; Midd | 2002 |
Diuretics as initial treatment for essential hypertension.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Diuretics; Drug Therapy, Combination; Humans; Hyperg | 1979 |
The role of muscle cell injury in the pathogenesis of acute renal failure after exercise.
Topics: Acute Kidney Injury; Adenosine Triphosphatases; Aldosterone; Animals; Creatine Kinase; Dogs; Hot Tem | 1976 |
Adverse reactions to frusemide in hospital inpatients.
Topics: Aged; Drug Administration Schedule; Female; Furosemide; Hospitalization; Humans; Hypokalemia; Male; | 1979 |
The effect of thiazide diuretics on coronary risk factors.
Topics: Aged; Benzothiadiazines; Blood Glucose; Coronary Disease; Diuretics; Female; Hematocrit; Humans; Hyp | 1979 |
[Diuretics in cardiac insufficiency].
Topics: Alkalosis; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diuretics; Diuretics, Osmotic; Heart Fa | 1977 |
Diuretics in the treatment of hypertension.
Topics: Benzothiadiazines; Diuretics; Humans; Hyperglycemia; Hypertension; Hypokalemia; Sodium Chloride Symp | 1978 |
Biochemical consequences of diuretic therapy in hypertension.
Topics: Benzothiadiazines; Diuretics; Humans; Hypercalcemia; Hyperglycemia; Hypertension; Hypokalemia; Sodiu | 1978 |
The purine nucleotide cycle. A pathway for ammonia production in the rat kidney.
Topics: Adenine Nucleotides; Allopurinol; Ammonia; Ammonium Chloride; AMP Deaminase; Animals; Aspartic Acid; | 1976 |
[Dr. Atkins' dietetic revolution: a critique].
Topics: Acidosis; Adult; Cholesterol; Diet, Reducing; Dietary Carbohydrates; Dietary Fats; Energy Intake; Hu | 1977 |
Nephrotoxicity of dietary ochratoxin A in broiler chickens.
Topics: Animal Feed; Animals; Chickens; Hypokalemia; Kidney Diseases; Kidney Function Tests; Male; Ochratoxi | 1975 |
[Editorial: Edema from diuretics abuse].
Topics: Adult; Diuretics; Edema; Female; Humans; Hyperaldosteronism; Hyperglycemia; Hypokalemia; Hyponatremi | 1976 |
[The side effects and complications in treatment with diuretic preparations. 2].
Topics: Diuretics; Drug Hypersensitivity; Humans; Hypercalcemia; Hyperkalemia; Hypocalcemia; Hypokalemia; Ma | 1992 |
[Negative effects of diuretics].
Topics: Alkalosis; Diuretics; Heart Diseases; Humans; Hyperglycemia; Hypokalemia; Hyponatremia; Insulin; Liv | 1985 |
Diuretic therapy update.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Diet, Sodium-Restricted; Diuretics; Ear Diseases; Heart Fa | 1985 |
Side effects of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazine | 1974 |
Death from weight-control pills. A case report with objective postmortem confirmation.
Topics: Adult; Amphetamine; Appetite Depressants; Arrhythmias, Cardiac; Death, Sudden; Digitalis Glycosides; | 1969 |
[Side effects and complication possibilities following high-dosage furosemide treatment].
Topics: Adult; Aged; Alkalosis; Blood Coagulation Disorders; Blood Glucose; Dehydration; Drug Eruptions; Ear | 1972 |
[Side effects of antihypertensive agents].
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Diarrhea; Diuretics; Fatigue; Ganglionic Blockers; Ga | 1970 |
[Side effects of diuretics].
Topics: Adolescent; Adult; Aged; Benzothiadiazines; Child; Diuretics; Female; Furosemide; Humans; Hypokalemi | 1974 |
Self-induced secondary hyperaldosteronism simulating Bartter's syndrome.
Topics: Adult; Alkalosis; Diagnosis, Differential; Female; Furosemide; Humans; Hyperaldosteronism; Hypertrop | 1972 |
Nephrotoxicity of amphotericin B, with emphasis on changes in tubular function.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Amphotericin B; Blastomycosis; Carbon Dioxide; Glome | 1972 |
Electrolyte disturbances resulting from diuretic therapy.
Topics: Acetazolamide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Hypokalemia; Hyponatre | 1973 |
Diuretic and diet treatment of hypertension.
Topics: Benzothiadiazines; Blood Volume; Chlorthalidone; Creatinine; Diet, Sodium-Restricted; Diuretics; Eth | 1974 |
Nephrotoxicity of amphotericin B, with emphasis on changes in tubular function.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Amphotericin B; Blastomycosis; Carbon Dioxide; Glome | 1972 |
Trial of mefruside.
Topics: Diuretics; Humans; Hypertension; Hypokalemia; Sulfonic Acids; Uric Acid | 1972 |
Lysozymuria and renal tubular dysfunction in monocytic and myelomonocytic leukemia.
Topics: Acidosis, Renal Tubular; Adult; Aged; Ammonia; Calcium; Chlorides; Creatinine; Female; Humans; Hydro | 1969 |
[Guidelines for therapy with diuretics].
Topics: Alkalosis; Carbohydrate Metabolism; Diuretics; Drug Synergism; Glaucoma; Humans; Hypertension; Hypok | 1970 |
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure.
Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, R | 1971 |
Serum electrolyte changes during ling-term treatment with amiloride hydrochloride (MK-870).
Topics: Adult; Aged; Blood Gas Analysis; Body Weight; Carbon Dioxide; Chlorides; Creatinine; Digitalis Glyco | 1968 |
Renal tubular acidosis in cirrhosis. A determinant of susceptibility to recurrent hepatic precoma.
Topics: Acidosis, Renal Tubular; Ammonia; Ammonium Chloride; Blood Urea Nitrogen; Calcium; Calcium Chloride; | 1969 |
Metabolic hazards of fasting.
Topics: Adult; Anemia; Autoanalysis; Blood Cell Count; Blood Proteins; Blood Urea Nitrogen; Body Weight; Chl | 1969 |
Potassium depletion produced by administration of chlorthalidone to nonedematous patients with arterial hypertensin.
Topics: Adult; Alkalosis; Blood Urea Nitrogen; Carbon Dioxide; Chlorine; Chlorthalidone; Creatine; Female; H | 1966 |