Page last updated: 2024-10-20

uric acid and Hypertriglyceridemia

uric acid has been researched along with Hypertriglyceridemia in 69 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.

Research Excerpts

ExcerptRelevanceReference
"This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia."9.34Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia. ( Liu, J; Sun, X; Wang, G, 2020)
"To describe the effect of Coenzyme Q10 (CoQ10) (added to either a fibrate, or polyunsaturated fatty acids (PUFA) or association of both) in patients affected by massive hypertriglyceridemia (MHTG) resistant to fibrates and PUFA."9.11Possible role of ubiquinone in the treatment of massive hypertriglyceridemia resistant to PUFA and fibrates. ( Cicero, AF; Derosa, G; Gaddi, A; Laghi, L; Miconi, A; Nascetti, S, 2005)
"These favourable effects of comicronised fenofibrate both on lipid and non lipid parameters, including insulin sensitivity, may confer to this product a particular interest in the treatment of patients with polymetabolic syndrome X."9.09Effects of comicronised fenofibrate on lipid and insulin sensitivity in patients with polymetabolic syndrome X. ( Blane, G; Idzior-Walus, B; Kawalec, E; Rostworowski, W; Sieradzki, J; Wójcik, J; Zarnecki, A; Zdzienicka, A, 2000)
"Accumulating evidence suggests that elevated serum uric acid (SUA) may be a risk factor for hypertriglyceridemia (HTG)."8.31The association between serum uric acid and hypertriglyceridemia: evidence from the national health and nutrition examination survey (2007-2018). ( Li, F; Mo, CY; Tan, MY; Zhao, Q, 2023)
"This study investigated the association between serum uric acid (sUA) and stroke risk in men with hypertriglyceridemia."7.91Is serum uric acid a predictive factor for stroke in men with hypertriglyceridemia? ( Hsu, CY; Lai, YJ, 2019)
"Uric acid-lowering therapy benefits hyperlipidemia in gouty patients."7.91Efficacy of uric acid-lowering therapy on hypercholesterolemia and hypertriglyceridemia in gouty patients. ( Deng, JX; Jie, LG; Qu, Y; Wu, J; Yu, QH; Zhang, YP, 2019)
"Hypertriglyceridemia is one of lipid metabolism abnormalities; however, it is still debatable whether serum uric acid is a cause or a consequence of hypertriglyceridemia."7.85Serum Uric Acid Levels and Risk of Incident Hypertriglyceridemia: A Longitudinal Population-based Epidemiological Study. ( Chen, C; Chen, Q; Mao, Y; Ren, P; Yang, T; Zheng, R, 2017)
"Several studies have demonstrated a relationship between increased serum uric acid (SUA) concentrations and the prevalence of metabolic syndrome (MetS) in the oriental population."7.81Associations between serum uric acid concentrations and metabolic syndrome and its components in the PREDIMED study. ( Babio, N; Basora, J; Becerra-Tomás, N; Corella, D; Estruch, R; Fitó, M; Martínez-González, MA; Ortega-Calvo, M; Recondo, J; Ros, E; Salas-Salvadó, J; Serra-Majem, L; Wärnberg, J, 2015)
"The relationship between uric acid metabolism and lipid levels was analyzed in 148 male subjects with primary gout."7.67Relationship between hypertriglyceridemia and uric acid production in primary gout. ( Jiao, S; Kubo, M; Matsubara, K; Matsuzawa, Y; Takama, T; Tarui, S, 1989)
"Hyperuricemia is associated with metabolic syndrome (MetS), but the association is often confounded by the shared background of obesity."5.46Combined effect of obesity and uric acid on nonalcoholic fatty liver disease and hypertriglyceridemia. ( Du, T; Li, M; Lin, X; Lu, H; Yu, X; Zhang, S, 2017)
"Hyperuricemia was defined as SUA ≥70 mg/L in men and ≥60 mg/L in women."5.38Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome. ( Gonçalves, JP; Lopes, C; Oliveira, A; Santos, AC; Severo, M, 2012)
"Uric acid (UA) has been frequently reported to be associated with MetS in the general population."5.38The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder. ( Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Lu, ML; Tsai, CJ, 2012)
"Moreover, hyperuricemia is significantly correlated with hypertriglyceridemia, hypertension, and visceral obesity."5.35Serum uric acid levels and risk of metabolic syndrome in healthy adults. ( Bandarian, F; Ebrahimpour, P; Fakhrzadeh, H; Heshmat, R; Larijani, B, 2008)
"This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia."5.34Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia. ( Liu, J; Sun, X; Wang, G, 2020)
"Metabolic syndrome was diagnosed using the WHO criteria."5.34Serum uric acid level as an independent component of the metabolic syndrome in type 2 diabetic blacks. ( Akande, AA; Akinyinka, OA; Jimoh, AK; Olarinoye, GO, 2007)
"To describe the effect of Coenzyme Q10 (CoQ10) (added to either a fibrate, or polyunsaturated fatty acids (PUFA) or association of both) in patients affected by massive hypertriglyceridemia (MHTG) resistant to fibrates and PUFA."5.11Possible role of ubiquinone in the treatment of massive hypertriglyceridemia resistant to PUFA and fibrates. ( Cicero, AF; Derosa, G; Gaddi, A; Laghi, L; Miconi, A; Nascetti, S, 2005)
"These favourable effects of comicronised fenofibrate both on lipid and non lipid parameters, including insulin sensitivity, may confer to this product a particular interest in the treatment of patients with polymetabolic syndrome X."5.09Effects of comicronised fenofibrate on lipid and insulin sensitivity in patients with polymetabolic syndrome X. ( Blane, G; Idzior-Walus, B; Kawalec, E; Rostworowski, W; Sieradzki, J; Wójcik, J; Zarnecki, A; Zdzienicka, A, 2000)
" The link between increased fructose consumption and increases in uric acid also has been confirmed as a potential risk factor for metabolic syndrome, and insulin resistance/hyperinsulinemia may be causally related to the development of hypertension."4.91Health implications of high-fructose intake and current research. ( de Lima, WG; Dornas, WC; Pedrosa, ML; Silva, ME, 2015)
" Apart from the diagnostic criteria, MetS has also been associated with other risk factors including waist to hip ratio, high density lipoprotein dysfunction, small dense low density lipoprotein, postprandial hypertriglyceridaemia, lipoprotein (a), uric acid, liver function tests, prothrombotic factors, cytokines, adipokines, vitamin D, arterial stiffness, renal dysfunction, nephrolithiasis, polycystic ovary syndrome, obstructive sleep apnea."4.90Characteristics other than the diagnostic criteria associated with metabolic syndrome: an overview. ( Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP, 2014)
"Accumulating evidence suggests that elevated serum uric acid (SUA) may be a risk factor for hypertriglyceridemia (HTG)."4.31The association between serum uric acid and hypertriglyceridemia: evidence from the national health and nutrition examination survey (2007-2018). ( Li, F; Mo, CY; Tan, MY; Zhao, Q, 2023)
" 113 patients fulfilled the criteria for central obesity with the mean uric acid level of 8."4.12A Clinical Profile of Patients with Hyperuricemia and the Relationship between Hyperuricemia and Metabolic Syndrome: A Cross-sectional Study at a Tertiary Hospital in the Indian Population. ( Ingawale, S; Raghorte, N; Rajadhyaksha, A; Sarate, N, 2022)
"This study investigated the association between serum uric acid (sUA) and stroke risk in men with hypertriglyceridemia."3.91Is serum uric acid a predictive factor for stroke in men with hypertriglyceridemia? ( Hsu, CY; Lai, YJ, 2019)
"Uric acid-lowering therapy benefits hyperlipidemia in gouty patients."3.91Efficacy of uric acid-lowering therapy on hypercholesterolemia and hypertriglyceridemia in gouty patients. ( Deng, JX; Jie, LG; Qu, Y; Wu, J; Yu, QH; Zhang, YP, 2019)
"Hypertriglyceridemia is one of lipid metabolism abnormalities; however, it is still debatable whether serum uric acid is a cause or a consequence of hypertriglyceridemia."3.85Serum Uric Acid Levels and Risk of Incident Hypertriglyceridemia: A Longitudinal Population-based Epidemiological Study. ( Chen, C; Chen, Q; Mao, Y; Ren, P; Yang, T; Zheng, R, 2017)
"Several studies have demonstrated a relationship between increased serum uric acid (SUA) concentrations and the prevalence of metabolic syndrome (MetS) in the oriental population."3.81Associations between serum uric acid concentrations and metabolic syndrome and its components in the PREDIMED study. ( Babio, N; Basora, J; Becerra-Tomás, N; Corella, D; Estruch, R; Fitó, M; Martínez-González, MA; Ortega-Calvo, M; Recondo, J; Ros, E; Salas-Salvadó, J; Serra-Majem, L; Wärnberg, J, 2015)
" With the reduction of serum potassium quartiles, participants were tended to have higher level of triglycerides and uric acid, lower level of high-density lipoprotein cholesterol (HDL-C), larger waist circumference and more severe insulin resistance."3.80Serum potassium level is associated with metabolic syndrome: a population-based study. ( Bi, Y; Li, M; Liu, J; Lu, J; Ning, G; Su, T; Sun, K; Xu, B; Xu, M, 2014)
"The increasing of uric acid level (hyperuricosuria) is regularly detected in blood during the examination of patient with such cardiovascular diseases as arterial hypertension, atherosclerosis, diabetes mellitus, metabolic syndrome and obesity."3.78[The hyperuricosuria in patients with high content of triglycerides: the combination of genetic and environmental factors and tactics of treatment]. ( Ameliushkina, VA; Iarovaia, EB; Kotkina, TI; Malusheva, PP; Rozhkova, TA; Titov, VN, 2012)
" Potassium supplementation improves their insulin resistance and hypertension, whereas allopurinol reduces serum levels of uric acid and ameliorates hypertension, hypertriglyceridemia, hyperglycemia, and insulin resistance."3.74Thiazide diuretics exacerbate fructose-induced metabolic syndrome. ( Johnson, RJ; Mu, W; Nakagawa, T; Reungjui, S; Roncal, CA; Sirivongs, D; Srinivas, TR, 2007)
"The prevalence of hypertriglyceridemia significantly increased with increased level of serum uric acid among both the men and women."3.73[Association between serum uric acid and triglyceride in a Chinese community]. ( Liu, J; Liu, S; Qin, LP; Wang, W; Wang, WH; Wu, GX; Zeng, ZC; Zhao, D; Zhao, LJ, 2005)
" The diabetic dams presented hyperglycemia, hyperlipemia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, decreased reduced glutathione (GSH), hepatic glycogen and superoxide dismutase (SOD) determinations."3.71Oxidative stress and diabetes in pregnant rats. ( Cunha Rudge, MV; Damasceno, DC; de Mattos Paranhos Calderon, I; Volpato, GT, 2002)
" The high prevalence and severity of metabolic disturbances associated with the insulin resistance syndrome (hyperglycaemia, hyperinsulinaemia, decreased HDL cholesterol, hypertriglyceridaemia, elevated fibrinogen levels and hyperuricaemia) before gastroplasty were significantly decreased after weight loss."3.70Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity. ( Desaive, C; Dewe, W; Gielen, JE; Lefebvre, PJ; Luyckx, FH; Scheen, AJ, 1998)
"We carried out a study of 43 male asymptomatic subjects with high levels of uric acid but showing no signs of arterial hypertension, obesity or alcohol abuse."3.68Hyperuricemia-hyperlipemia association in the absence of obesity and alcohol abuse. ( Añon Barbudo, J; Collantes Estevez, E; Pineda Priego, M; Sanchez Guijo, P, 1990)
"The relationship between uric acid metabolism and lipid levels was analyzed in 148 male subjects with primary gout."3.67Relationship between hypertriglyceridemia and uric acid production in primary gout. ( Jiao, S; Kubo, M; Matsubara, K; Matsuzawa, Y; Takama, T; Tarui, S, 1989)
"Fenofibrate is a marketed fibric acid derivative for lipid-lowering in patients with lipid disorders."2.72Impact of fenofibrate therapy on serum uric acid concentrations: a review and meta-analysis. ( Chen, Y; Dong, Z; Ji, X; Li, C; Li, R; Lu, J; Zhang, J; Zhao, Y, 2021)
"Hyperuricemia were defined as serum uric acid levels ≥7."1.56Sex-specific association of hyperuricemia with cardiometabolic abnormalities in a military cohort: The CHIEF study. ( Hoshide, S; Kwon, Y; Lee, JT; Lin, CS; Lin, GM; Lin, YK; Lin, YP; Su, FY; Tsai, KZ; Wu, TJ, 2020)
"The overall prevalence of NAFLD was 28."1.56Associations between obesity and metabolic health with nonalcoholic fatty liver disease in elderly Chinese. ( Chen, G; Chen, XH; He, H; Kuang, Y; Lin, BY; Wu, LM; Zheng, SS, 2020)
" KEY MESSAGES The natural cubic spline model showed a positive linear dose-response relationship between serum uric acid levels and hypertriglyceridaemia."1.56Serum uric acid and risk of incident hypercholesterolaemia and hypertriglyceridaemia in middle-aged and older Chinese: a 4-year prospective cohort study. ( Jia, C; Li, Y; Tian, L; Zheng, H, 2020)
"Hyperuricemia is associated with metabolic syndrome (MetS), but the association is often confounded by the shared background of obesity."1.46Combined effect of obesity and uric acid on nonalcoholic fatty liver disease and hypertriglyceridemia. ( Du, T; Li, M; Lin, X; Lu, H; Yu, X; Zhang, S, 2017)
"Hyperuricemia is characterized by inhibited nitric oxide system and enhanced synthesis of reactive oxygen species."1.42Uric acid levels and the risk of Contrast Induced Nephropathy in patients undergoing coronary angiography or PCI. ( Barbieri, L; Cassetti, E; De Luca, G; Marino, P; Schaffer, A; Suryapranata, H; Verdoia, M, 2015)
" The high and low dosage of chicory inulin also decreased serum UA levels on days 7, 14, and 28."1.40Effects of chicory inulin on serum metabolites of uric acid, lipids, glucose, and abdominal fat deposition in quails induced by purine-rich diets. ( Jin, R; Lin, Z; Liu, X; Zhang, B; Zhu, W, 2014)
"Hyperuricemia was defined as SUA ≥70 mg/L in men and ≥60 mg/L in women."1.38Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome. ( Gonçalves, JP; Lopes, C; Oliveira, A; Santos, AC; Severo, M, 2012)
"Uric acid (UA) has been frequently reported to be associated with MetS in the general population."1.38The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder. ( Chen, CH; Chen, PY; Chiu, CC; Huang, MC; Lu, ML; Tsai, CJ, 2012)
"Hyperuricemia was defined as ≥ 6."1.38Gender distribution of serum uric acid and cardiovascular risk factors: population based study. ( Baldo, MP; Capingana, P; Dantas, EM; Magalhães, P; Mill, JG; Molina, Mdel C; Morelato, RL; Rodrigues, SL; Salaroli, LB, 2012)
"Moreover, hyperuricemia is significantly correlated with hypertriglyceridemia, hypertension, and visceral obesity."1.35Serum uric acid levels and risk of metabolic syndrome in healthy adults. ( Bandarian, F; Ebrahimpour, P; Fakhrzadeh, H; Heshmat, R; Larijani, B, 2008)
"Thus, cancer cells can no longer divide and cancer activity is inhibited."1.34Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im ( Chen, Y; Duvvi, H; Lu, DP; Ohki, M; Omura, Y; Shimotsura, Y, 2007)
"Metabolic syndrome was diagnosed using the WHO criteria."1.34Serum uric acid level as an independent component of the metabolic syndrome in type 2 diabetic blacks. ( Akande, AA; Akinyinka, OA; Jimoh, AK; Olarinoye, GO, 2007)
"Hyperuricemia and gout have shown an increase worldwide."1.33The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China. ( Dong, Y; Gao, W; Nan, H; Qian, R; Qiao, Q; Tang, B; Tuomilehto, J, 2006)
"Insulin resistance is a risk factors for non-alcoholic fatty liver disease (NAFLD) and for gallstone disease (GD)."1.33Gallstone disease in non-alcoholic fatty liver: prevalence and associated factors. ( Bertolotti, M; Carulli, L; Carulli, N; D'Amico, R; Ganazzi, D; Lombardini, S; Lonardo, A; Loria, P; Rudilosso, A; Verrone, A, 2005)
"In idiopathic uric acid nephrolithiasis, urinary pH and fractional excretion of urate are significantly lower than in control subjects, suggestive of defects in urinary acidification and urate excretion."1.31Biochemical profile of idiopathic uric acid nephrolithiasis. ( Frawley, WH; Pak, CY; Peterson, RD; Poindexter, JR; Sakhaee, K, 2001)
"The prognosis of IgA nephropathy (IgAN) is variable and about 10-20% of patients progress to end-stage renal disease (ESRD) in 10 years."1.31Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy. ( Mustonen, J; Pasternack, A; Syrjänen, J, 2000)
"Patients with NIDDM had 11% increase of high density lipoprotein-cholesterol (HDL-C) level at the end of the first, and 18% increase at the end of the second month, while patients with primary hyperlipoproteinaemia did not change significantly."1.30Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia. ( Balogh, Z; Boda, J; Kárpáti, L; Kovács, P; Leövey, A; Paragh, G; Szabó, J, 1997)
"Insulin resistance was estimated by homeostasis model assessment (HOMA(IR)), preliminarily validated against a euglycemic-hyperinsulinemic clamp in 85 subjects."1.30Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. ( Alberiche, M; Bonadonna, RC; Bonora, E; Egger, G; Kiechl, S; Muggeo, M; Oberhollenzer, F; Targher, G; Willeit, J, 1998)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.90)18.7374
1990's14 (20.29)18.2507
2000's17 (24.64)29.6817
2010's26 (37.68)24.3611
2020's10 (14.49)2.80

Authors

AuthorsStudies
Rajadhyaksha, A1
Sarate, N1
Raghorte, N1
Ingawale, S1
Teramura, S1
Yamagishi, K1
Umesawa, M1
Hayama-Terada, M1
Muraki, I1
Maruyama, K1
Tanaka, M1
Kishida, R1
Kihara, T1
Takada, M1
Ohira, T1
Imano, H1
Shimizu, Y1
Sankai, T1
Okada, T1
Kitamura, A1
Kiyama, M1
Iso, H1
Tan, MY1
Mo, CY1
Li, F1
Zhao, Q1
Kim, YK1
Yang, YM1
Lin, YK1
Lin, YP1
Lee, JT1
Lin, CS1
Wu, TJ1
Tsai, KZ1
Su, FY1
Kwon, Y1
Hoshide, S1
Lin, GM1
Wu, LM1
He, H1
Chen, G1
Kuang, Y1
Lin, BY1
Chen, XH1
Zheng, SS1
Sun, X1
Liu, J4
Wang, G1
Li, Y1
Tian, L1
Zheng, H1
Jia, C1
Yu, X3
Wang, T1
Huang, S1
Zeng, P1
Zhang, J1
Ji, X1
Dong, Z1
Lu, J2
Zhao, Y1
Li, R1
Li, C1
Chen, Y2
Zhang, S1
Du, T1
Li, M2
Lu, H1
Lin, X1
Zheng, R1
Ren, P1
Chen, Q1
Yang, T1
Chen, C1
Mao, Y1
Alegría-Díaz, A1
Valdez-Ortiz, R1
Murguía-Romero, M1
Jiménez-Flores, R1
Villalobos-Molina, R1
Mummidi, S1
Duggirala, R1
López-Alvarenga, JC1
Pérez-Navarro, M1
Kuwabara, M1
Borghi, C1
Cicero, AFG1
Hisatome, I1
Niwa, K1
Ohno, M1
Johnson, RJ2
Lanaspa, MA1
Hou, YL1
Yang, XL1
Wang, CX1
Zhi, LX1
Yang, MJ1
You, CG1
Lai, YJ1
Hsu, CY1
Wu, J1
Zhang, YP1
Qu, Y1
Jie, LG1
Deng, JX1
Yu, QH1
Katsiki, N1
Athyros, VG2
Karagiannis, A2
Mikhailidis, DP2
Sun, K1
Su, T1
Xu, B1
Xu, M1
Bi, Y1
Ning, G1
Lin, Z1
Zhang, B1
Liu, X1
Jin, R1
Zhu, W1
Barbieri, L1
Verdoia, M1
Schaffer, A1
Cassetti, E1
Marino, P1
Suryapranata, H1
De Luca, G1
Babio, N1
Martínez-González, MA1
Estruch, R1
Wärnberg, J1
Recondo, J1
Ortega-Calvo, M1
Serra-Majem, L1
Corella, D1
Fitó, M1
Ros, E1
Becerra-Tomás, N1
Basora, J1
Salas-Salvadó, J1
Chen, S1
Guo, X2
Zhang, X1
Yu, S2
Yang, H2
Jiang, M1
Sun, G1
Sun, Y2
Zheng, L1
Dornas, WC1
de Lima, WG1
Pedrosa, ML1
Silva, ME1
Ai, Z1
Xu, R1
Liu, W1
Zhou, Q1
Li, B1
Huang, F1
Yang, Q1
Liang, S1
Hu, Y1
Liu, C1
Qi, J1
Li, G1
Anagnostis, P1
Tziomalos, K1
Hauenschild, A1
Bretzel, RG1
Schnell-Kretschmer, H1
Kloer, HU1
Hardt, PD1
Ewald, N1
Wiernsperger, N1
Geloen, A1
Rapin, JR1
Rodrigues, SL1
Baldo, MP1
Capingana, P1
Magalhães, P1
Dantas, EM1
Molina, Mdel C1
Salaroli, LB1
Morelato, RL1
Mill, JG1
Gonçalves, JP1
Oliveira, A1
Severo, M1
Santos, AC1
Lopes, C1
Kawada, T1
Miglio, C1
Peluso, I1
Raguzzini, A1
Villaño, DV1
Cesqui, E1
Catasta, G1
Toti, E1
Serafini, M1
Chiu, CC1
Chen, CH1
Huang, MC1
Chen, PY1
Tsai, CJ1
Lu, ML1
Rozhkova, TA1
Ameliushkina, VA1
Iarovaia, EB1
Kotkina, TI1
Malusheva, PP1
Titov, VN1
He, S1
Chen, XP1
Jiang, LY1
Peng, Y1
He, JY1
Gong, L1
Wu, K1
Cui, KJ1
Zhu, Y1
Huang, DJ1
Damasceno, DC1
Volpato, GT1
de Mattos Paranhos Calderon, I1
Cunha Rudge, MV1
FELDMAN, EB1
WALLACE, SL1
Nakanishi, N1
Nishina, K1
Okamoto, M1
Yoshida, H1
Matsuo, Y1
Suzuki, K1
Tatara, K1
Balasubramanian, T1
Cicero, AF2
Derosa, G2
Miconi, A2
Laghi, L2
Nascetti, S2
Gaddi, A2
Loria, P1
Lonardo, A1
Lombardini, S1
Carulli, L1
Verrone, A1
Ganazzi, D1
Rudilosso, A1
D'Amico, R1
Bertolotti, M1
Carulli, N1
Zhao, LJ1
Zhao, D1
Wang, W1
Wu, GX1
Qin, LP1
Liu, S1
Wang, WH1
Zeng, ZC1
Nan, H1
Qiao, Q1
Dong, Y1
Gao, W1
Tang, B1
Qian, R1
Tuomilehto, J1
Reungjui, S1
Roncal, CA1
Mu, W1
Srinivas, TR1
Sirivongs, D1
Nakagawa, T1
Akande, AA1
Jimoh, AK1
Akinyinka, OA1
Olarinoye, GO1
Omura, Y1
Lu, DP1
Shimotsura, Y1
Ohki, M1
Duvvi, H1
Ebrahimpour, P1
Fakhrzadeh, H1
Heshmat, R1
Bandarian, F1
Larijani, B1
Tinahones, FJ1
Collantes, E2
C-Soriguer, FJ2
González-Ruiz, A1
Pineda, M1
Añón, J1
Sánchez Guijo, P2
Schmidt, MI1
Duncan, BB1
Watson, RL1
Sharrett, AR1
Brancati, FL1
Heiss, G1
Drabo, PY1
Guira, O1
Ouandaogo, BJ1
Kabore, J1
Kunes, J1
Dobesová, Z1
Zicha, J1
Nakamura, H1
Tinahones, JF1
Pérez-Lindón, G1
Pareja, A1
Sánchez-Guijo, P1
Paragh, G1
Balogh, Z1
Boda, J1
Kovács, P1
Kárpáti, L1
Szabó, J1
Leövey, A1
Zhioua, R1
Sebaï, L1
Kriaa, L1
el Euch, M1
Mabrouk, S1
Ouertani, A1
Leyva, F1
Wingrove, CS1
Godsland, IF1
Stevenson, JC1
Adachi, H1
Jacobs, DR1
Hashimoto, R1
Tsuruta, M1
Imaizumi, T1
Bonora, E1
Kiechl, S1
Willeit, J1
Oberhollenzer, F1
Egger, G1
Targher, G1
Alberiche, M1
Bonadonna, RC1
Muggeo, M1
Luyckx, FH1
Scheen, AJ1
Desaive, C1
Dewe, W1
Gielen, JE1
Lefebvre, PJ1
Emmerson, B1
Syrjänen, J1
Mustonen, J1
Pasternack, A1
Idzior-Walus, B1
Sieradzki, J1
Rostworowski, W1
Zdzienicka, A1
Kawalec, E1
Wójcik, J1
Zarnecki, A1
Blane, G1
Treviño-Becerra, A1
Pak, CY1
Sakhaee, K1
Peterson, RD1
Poindexter, JR1
Frawley, WH1
Collantes Estevez, E1
Pineda Priego, M1
Añon Barbudo, J1
Matsubara, K1
Matsuzawa, Y1
Jiao, S1
Takama, T1
Kubo, M1
Tarui, S1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Open-label, Parallel, Controlled Study to Evaluate the Efficacy of Fenofibrate on Microalbuminuria in Hypertriglyceridemic Patients With Type 2 Diabetes on Top of Statin Therapy[NCT02314533]Phase 4200 participants (Anticipated)Interventional2014-12-31Not yet recruiting
Effects of the Glucocorticoid Antagonist, Mifepristone, on Glucose Intolerance in Obese and Overweight Individuals[NCT01419535]Phase 1/Phase 219 participants (Actual)Interventional2011-11-29Completed
Uric Acid and Hypertension in African Americans[NCT00241839]Phase 3150 participants (Actual)Interventional2005-08-31Completed
Phase IV Study of Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia[NCT00595504]Phase 425 participants (Actual)Interventional2008-01-31Completed
Omentectomy for Treatment of Diabetes Mellitus Type 2[NCT00270439]Phase 110 participants (Actual)Interventional2006-01-31Completed
Phase 4 Study of the Effects of Pravastatin on Cholesterol Levels, Inflammation and Cognition in Schizophrenia[NCT01082588]Phase 460 participants (Actual)Interventional2010-06-30Completed
Effects of Fenofibrate on Metabolic and Reproductive Parameters in Polycystic Ovary Syndrome. A Randomized, Double-Blind, Placebo-Controlled Trial[NCT00884819]4 participants (Actual)Interventional2008-12-31Terminated (stopped due to Poor recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adipose-tissue Insulin Resistance Index (Adipo-IR)

The adipose tissue insulin resistance index (Adipo-IR), a surrogate measure for fasting adipose-tissue insulin resistance, was calculated as the product of fasting insulin and fasting free fatty acids (FFA) (NCT01419535)
Timeframe: 9 days

Interventionmmol/l·μU/l (Mean)
Post-mifepristone49.9
Post-placebo65.5

Adipose-tissue Insulin Sensitivity Index (Adipo-SI)

The Adipo-SI was calculated as ratio of the slope of the linear decrease in natural log transformed FFA [Ln (FFA) slope] during the first 90 minutes of the FSIVGTT and the area under the curve (AUC) of insulin during that 90-minute period (AUC Insulin 0-90 min). (NCT01419535)
Timeframe: 9 days

Interventionln(mmol /uU/mL*min)*10^8 (Mean)
Post-mifepristone61.7
Post-placebo42.8

Change in Fasting Insulin Levels

Fasting insulin after study agent administration compared to baseline (NCT01419535)
Timeframe: 9 days

Interventionpmol/L (Mean)
Post-mifepristone95.6
Post-placebo142.8

Change in Fasting Plasma Glucose

fasting plasma glucose after study agent compared to baseline (NCT01419535)
Timeframe: Nine days

Interventionmg/dL (Mean)
Post-mifepristone100.4
Post-placebo107.8

Change in Insulin Sensitivity Index

insulin sensitivity index based on the effect of insulin on glucose during frequently sampled intravenous glucose tolerance test (FSIVGTT) (NCT01419535)
Timeframe: Nine days

Interventionmin-1·μU·ml-1 (Mean)
Post-mifepristone1.49
Post-placebo1.41

Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)

HOMA-IR is an index of insulin resistance, measured as glucose in mmol/L x insulin in mIU/mL)/22.5. HOMA-IR > 2.5 indicates insulin resistance. (NCT01419535)
Timeframe: 9 days

Interventionunits on a scale (Mean)
Post-mifepristone3.58
Post-placebo5.78

Change in Diastolic Blood Pressure by Cuff 8-10 Weeks Minus Baseline

"The Diastolic BP was taken at Baseline and after 8-10 weeks of treatment or placebo while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol / placebo

Interventionmm Hg (Mean)
A (Allopurinol)3.44
B (Placebo)-0.83

Change in Overall Mean BP From Those Obtained by 24 Hour Ambulatory Blood Pressure Measurements (ABPM) 8-10 Weeks Minus Baseline.

Subjects had 24 hr blood pressure monitoring (ABPM) at baseline and treatment end. The readings were averaged and the changes from baseline to treatment end were compared. (NCT00241839)
Timeframe: Baseline and end of treatment (8-10 weeks on allopurinol / placebo)

Interventionmm Hg (Mean)
A (Allopurinol)-5.9
B (Placebo)0.90

Change in Systolic Blood Pressure by Cuff After 8-10 Weeks Minus Baseline

"The systolic BP was taken at Baseline and after 8-10 weeks of treatment on placebo, while on chlorthalidone and potassium chloride. The blood pressure was measured according to Shared Care protocol: 15 minutes of quiet, undisturbed rest with three BP measurements obtained subsequently at 5 minute intervals.~The mean of the second and third reading was the value used for analysis for both the Baseline measurement and the measurement after 8 - 10 weeks of treatment. The dependent variable is baseline value minus ending value.~Measures are in millimeters of mercury (mm hg)" (NCT00241839)
Timeframe: Measured at 8-10 weeks on allopurinol or placebo

Interventionmm Hg (Mean)
A (Allopurinol)0.21
B (Placebo)-0.95

Change in Uric Acid (UA) Levels: Baseline Less End of Treatment

Subjects on allopurinol are expected to lower their uric acid levels relative to placebo. (NCT00241839)
Timeframe: Baseline UA levels compared to end of treatment levels (8-10 weeks on allopurinol / placebo)

Interventionmg/dl (Mean)
A (Allopurinol)2.29
B (Placebo)0.14

Change in Abdominal Fat (DEXA).

A comparison between the ramelteon group and the placebo group of change in abdominal fat measured by a DEXA scan, assessed at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8

Interventiong (Mean)
Ramelteon3934.86
Placebo (Sugar Pill)5120.92

Change in Insulin Resistance as Measured by the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).

A comparison between the ramelteon group and the placebo group of change in insulin resistance measured by the homeostatic model assessment of insulin resistance (HOMA-IR), assessed at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8

InterventionHOMA score (Mean)
Ramelteon2.4
Placebo (Sugar Pill)2.36

Change in Waist Circumference

A comparison between the ramelteon group and the placebo group in change in waist circumference (measured in cm) measured at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8

Interventioncm (Mean)
Ramelteon106.09
Placebo (Sugar Pill)108.37

Change in C-Reactive Protein (CRP) From Baseline to Week 12

(NCT01082588)
Timeframe: Baseline, week 12

Interventionmg/L (Mean)
Pravastatin0.8063
Placebo-0.5136

Change in LDL-cholesterol Between Baseline and Week 12

(NCT01082588)
Timeframe: Baseline, week 12

Interventionmg/dl (Mean)
Pravastatin-25.565
Placebo-2.913

Change in MATRICS Neuropsychological Battery Composite Score From Baseline to Week 12

"The Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery measures cognitive functioning within 7 domains: speed of processing, attention/vigilance, working memory (non verbal and verbal), verbal learning, visual learning, reasoning and problem solving and social cognition.~The composite score is calculated by the MATRICS computer program, which equally weights each of the 7 domain scores. The range of composite scores is 20-80. Higher scores indicate higher levels or cognitive functioning, while lower scores indicate lower levels of cognitive functioning." (NCT01082588)
Timeframe: Baseline, week 12

InterventionScores on a scale (Mean)
Pravastatin4.0417
Placebo4.125

Change in Positive and Negative Syndrome Scale (PANSS) General Score From Baseline to Week 12

This is a subscale of the Positive and Negative Syndrome Scale (PANSS). The range for this subscale is 15-105. All items are summed to calculate the total score. Better outcomes have lower numbers and worse outcomes have higher numbers. (NCT01082588)
Timeframe: Baseline, week 12

InterventionScores on a scale (Mean)
Pravastatin-5.625
Placebo-3.76

Change in Positive and Negative Syndrome Scale (PANSS) Negative Score From Baseline to Week 12

This is a subscale of the Positive and Negative Syndrome Scale (PANSS). The range for this subscale is 7-49. All items are summed to calculate the total score. Better outcomes have lower numbers and worse outcomes have higher numbers. (NCT01082588)
Timeframe: Baseline, week 12

InterventionScores on a scale (Mean)
Pravastatin-0.83
Placebo-0.28

Change in Positive and Negative Syndrome Scale (PANSS) Positive Score From Baseline to Week 12

This is a subscale of the Positive and Negative Syndrome Scale (PANSS). The range for this subscale is 7-49. All items are summed to calculate the total score. Better outcomes have lower numbers and worse outcomes have higher numbers. (NCT01082588)
Timeframe: Baseline, week 12

InterventionScores on a scale (Mean)
Pravastatin-2.9583
Placebo-2.44

Change in Positive and Negative Syndrome Scale (PANSS) Total Score From Baseline to Week 12

The Positive and Negative Syndrome Scale (PANSS) is a scale used to rate severity of schizophrenia. All items are summed to calculate the total score. The scale range is 30-210. Better outcomes have lower numbers and worse outcomes have higher numbers. (NCT01082588)
Timeframe: Baseline, week 12

InterventionScores on a scale (Mean)
Pravastatin-9.416
Placebo-6.48

Reviews

7 reviews available for uric acid and Hypertriglyceridemia

ArticleYear
Impact of fenofibrate therapy on serum uric acid concentrations: a review and meta-analysis.
    Endocrine journal, 2021, Jul-28, Volume: 68, Issue:7

    Topics: Fenofibrate; Humans; Hypertriglyceridemia; Treatment Outcome; Uric Acid

2021
Characteristics other than the diagnostic criteria associated with metabolic syndrome: an overview.
    Current vascular pharmacology, 2014, Volume: 12, Issue:4

    Topics: Endothelium, Vascular; Female; Humans; Hypertriglyceridemia; Lipoproteins, HDL; Lipoproteins, LDL; L

2014
Health implications of high-fructose intake and current research.
    Advances in nutrition (Bethesda, Md.), 2015, Volume: 6, Issue:6

    Topics: Animals; Diet; Dietary Sucrose; Fructose; Humans; Hypertension; Hypertriglyceridemia; Insulin; Insul

2015
Clinical review: The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipokines; Birth Weight; Blood Coagulation Disorders;

2009
Fructose and cardiometabolic disorders: the controversy will, and must, continue.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:7

    Topics: Diet; Fructose; Humans; Hypertriglyceridemia; Liver; Metabolic Syndrome; Risk Factors; Sweetening Ag

2010
[Association of hyperuricemia with hyperlipidemia and obesity].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:12

    Topics: Fatty Acids, Nonesterified; Female; Humans; Hypertriglyceridemia; Lipoprotein Lipase; Male; Obesity;

1996
The glycolytic pathway to coronary heart disease: a hypothesis.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:6

    Topics: Animals; Coronary Disease; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hypertrigl

1998

Trials

5 trials available for uric acid and Hypertriglyceridemia

ArticleYear
Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia.
    Lipids in health and disease, 2020, May-23, Volume: 19, Issue:1

    Topics: Adult; Aged; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fenofibrate; Gl

2020
Antioxidant and inflammatory response following high-fat meal consumption in overweight subjects.
    European journal of nutrition, 2013, Volume: 52, Issue:3

    Topics: Adult; Antioxidants; Body Mass Index; Diet, High-Fat; Female; Humans; Hypercholesterolemia; Hypertri

2013
Possible role of ubiquinone in the treatment of massive hypertriglyceridemia resistant to PUFA and fibrates.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005, Volume: 59, Issue:6

    Topics: Adult; Blood Pressure; Cholesterol; Coenzymes; Creatinine; Drug Resistance; Drug Therapy, Combinatio

2005
Dietary alterations in plasma very low density lipoprotein levels modify renal excretion of urates in hyperuricemic-hypertriglyceridemic patients.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:4

    Topics: Adult; Diet; Energy Intake; Humans; Hypertriglyceridemia; Kidney; Lipoproteins, VLDL; Male; Middle A

1997
Effects of comicronised fenofibrate on lipid and insulin sensitivity in patients with polymetabolic syndrome X.
    European journal of clinical investigation, 2000, Volume: 30, Issue:10

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Blood

2000

Other Studies

57 other studies available for uric acid and Hypertriglyceridemia

ArticleYear
A Clinical Profile of Patients with Hyperuricemia and the Relationship between Hyperuricemia and Metabolic Syndrome: A Cross-sectional Study at a Tertiary Hospital in the Indian Population.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:5

    Topics: Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Hypertriglyceridemia; Hyperuricemi

2022
Risk Factors for Hyperuricemia or Gout in Men and Women: The Circulatory Risk in Communities Study (CIRCS).
    Journal of atherosclerosis and thrombosis, 2023, Oct-01, Volume: 30, Issue:10

    Topics: Diabetes Mellitus; Female; Gout; Humans; Hypercholesterolemia; Hypertension; Hypertriglyceridemia; H

2023
The association between serum uric acid and hypertriglyceridemia: evidence from the national health and nutrition examination survey (2007-2018).
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adult; Cross-Sectional Studies; Humans; Hyperlipidemias; Hypertriglyceridemia; Nutrition Surveys; Ri

2023
An analysis of the associations of high-sensitivity C-reactive protein and uric acid with metabolic syndrome components in Korean adults by sex: a cross-sectional study using the Korea national health and nutrition examination survey 2016-2018.
    BMC endocrine disorders, 2023, Aug-03, Volume: 23, Issue:1

    Topics: Adult; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertriglyceridem

2023
Sex-specific association of hyperuricemia with cardiometabolic abnormalities in a military cohort: The CHIEF study.
    Medicine, 2020, Volume: 99, Issue:12

    Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertriglyceridemia; Hype

2020
Associations between obesity and metabolic health with nonalcoholic fatty liver disease in elderly Chinese.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2020, Volume: 19, Issue:3

    Topics: Aged; Blood Glucose; Blood Pressure; Body Mass Index; China; Cholesterol; Cross-Sectional Studies; F

2020
Serum uric acid and risk of incident hypercholesterolaemia and hypertriglyceridaemia in middle-aged and older Chinese: a 4-year prospective cohort study.
    Annals of medicine, 2020, Volume: 52, Issue:8

    Topics: Aged; Biomarkers; China; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Hypercholestero

2020
Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysis.
    Journal of human genetics, 2021, Volume: 66, Issue:5

    Topics: Age Factors; Causality; Cholesterol; Dyslipidemias; Genome-Wide Association Study; Gout; Humans; Hyp

2021
Combined effect of obesity and uric acid on nonalcoholic fatty liver disease and hypertriglyceridemia.
    Medicine, 2017, Volume: 96, Issue:12

    Topics: Adult; Aged; China; Cohort Studies; Cross-Sectional Studies; Female; Humans; Hypertriglyceridemia; H

2017
Serum Uric Acid Levels and Risk of Incident Hypertriglyceridemia: A Longitudinal Population-based Epidemiological Study.
    Annals of clinical and laboratory science, 2017, Volume: 47, Issue:5

    Topics: Adult; China; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Early Diagnosis; Female; Glomerular F

2017
Clinical Significance of Serum Uric Acid Levels in Mexican Young Adults.
    Contributions to nephrology, 2018, Volume: 192

    Topics: Adolescent; Adult; Cholesterol, LDL; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Hu

2018
Elevated serum uric acid increases risks for developing high LDL cholesterol and hypertriglyceridemia: A five-year cohort study in Japan.
    International journal of cardiology, 2018, 06-15, Volume: 261

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cholesterol, LDL; Cohort Studies; Female; Humans; Hypert

2018
Hypertriglyceridemia and hyperuricemia: a retrospective study of urban residents.
    Lipids in health and disease, 2019, Apr-01, Volume: 18, Issue:1

    Topics: Adult; Aged; Female; Humans; Hypertriglyceridemia; Hyperuricemia; Lipid Metabolism; Male; Middle Age

2019
Is serum uric acid a predictive factor for stroke in men with hypertriglyceridemia?
    Bratislavske lekarske listy, 2019, Volume: 120, Issue:4

    Topics: Aged; Biomarkers; Humans; Hypertriglyceridemia; Hyperuricemia; Male; Middle Aged; Predictive Value o

2019
Efficacy of uric acid-lowering therapy on hypercholesterolemia and hypertriglyceridemia in gouty patients.
    International journal of rheumatic diseases, 2019, Volume: 22, Issue:8

    Topics: Adult; Allopurinol; Benzbromarone; Biomarkers; Cholesterol; Febuxostat; Female; Gout; Gout Suppressa

2019
Serum potassium level is associated with metabolic syndrome: a population-based study.
    Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:3

    Topics: Aged; Asian People; Blood Glucose; Body Mass Index; China; Cholesterol, HDL; Cholesterol, LDL; Cross

2014
Effects of chicory inulin on serum metabolites of uric acid, lipids, glucose, and abdominal fat deposition in quails induced by purine-rich diets.
    Journal of medicinal food, 2014, Volume: 17, Issue:11

    Topics: Abdominal Fat; Acetyl-CoA Carboxylase; Animals; Blood Glucose; Cichorium intybus; Diet; Disease Mode

2014
Uric acid levels and the risk of Contrast Induced Nephropathy in patients undergoing coronary angiography or PCI.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Choleste

2015
Associations between serum uric acid concentrations and metabolic syndrome and its components in the PREDIMED study.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Asian People; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; C

2015
Association between elevated serum alanine aminotransferase and cardiometabolic risk factors in rural Chinese population: a cross-sectional study.
    BMC cardiovascular disorders, 2015, Jul-10, Volume: 15

    Topics: Adult; Age Factors; Aged; Alanine Transaminase; Blood Pressure; Body Mass Index; Cardiovascular Dise

2015
Hyperuricemia is independently associated with left ventricular hypertrophy in post-menopausal women but not in pre-menopausal women in rural Northeast China.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:9

    Topics: Adult; Age Factors; Aged; Body Mass Index; China; Diabetes Mellitus; Dyslipidemias; Female; Humans;

2015
Clinicopathologic features of IgA nephropathy patients with different levels of proteinuria.
    Clinical nephrology, 2016, Volume: 86, Issue:7

    Topics: Adult; Atrophy; Biopsy; Female; Fibrosis; Glomerular Filtration Rate; Glomerulonephritis, IGA; Glome

2016
Low insulin-like growth factor 1 is associated with low high-density lipoprotein cholesterol and metabolic syndrome in Chinese nondiabetic obese children and adolescents: a cross-sectional study.
    Lipids in health and disease, 2016, Jun-24, Volume: 15

    Topics: Adolescent; Alanine Transaminase; Blood Glucose; Body Mass Index; Case-Control Studies; Child; Chole

2016
Successful treatment of severe hypertriglyceridemia with a formula diet rich in omega-3 fatty acids and medium-chain triglycerides.
    Annals of nutrition & metabolism, 2010, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Glucose; Body Mass Index; Diet; Dietary Carbohydrates; Dietary Fats;

2010
Gender distribution of serum uric acid and cardiovascular risk factors: population based study.
    Arquivos brasileiros de cardiologia, 2012, Volume: 98, Issue:1

    Topics: Adult; Biomarkers; Body Mass Index; Brazil; Epidemiologic Methods; Female; Humans; Hypertension; Hyp

2012
Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome.
    Endocrine, 2012, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Confounding Factors, Epidemiologic; Cros

2012
Predictors of the development of metabolic syndrome in male workers: a 3-year follow-up study.
    Journal of occupational and environmental medicine, 2012, Volume: 54, Issue:3

    Topics: Adult; Age Factors; Alcohol Drinking; Cholesterol, HDL; Confidence Intervals; Exercise; Follow-Up St

2012
The relationship between serum uric acid concentration and metabolic syndrome in patients with schizophrenia or schizoaffective disorder.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:5

    Topics: Adult; Cholesterol, HDL; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertriglyceridemia

2012
[The hyperuricosuria in patients with high content of triglycerides: the combination of genetic and environmental factors and tactics of treatment].
    Klinicheskaia laboratornaia diagnostika, 2012, Issue:6

    Topics: Adolescent; Adult; Aged; Environment; Fructose; Humans; Hypertension; Hypertriglyceridemia; Lipoprot

2012
[Association between serum uric acid and prevalence of hypertriglyceridemia in middle and old aged people].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2010, Volume: 31, Issue:3

    Topics: Aged; Female; Humans; Hypertriglyceridemia; Male; Middle Aged; Prevalence; Uric Acid

2010
Oxidative stress and diabetes in pregnant rats.
    Animal reproduction science, 2002, Aug-15, Volume: 72, Issue:3-4

    Topics: Animals; Antioxidants; Congenital Abnormalities; Diabetes Mellitus, Experimental; Female; Gestationa

2002
HYPERTRIGLYCERIDEMIA IN GOUT.
    Circulation, 1964, Volume: 29

    Topics: Arteriosclerosis; Black People; Blood Chemical Analysis; Cholesterol; Genetics, Medical; Geriatrics;

1964
Clustering of components of the metabolic syndrome and risk for development of type 2 diabetes in Japanese male office workers.
    Diabetes research and clinical practice, 2004, Volume: 63, Issue:3

    Topics: Adult; Analysis of Variance; Blood Glucose; Body Mass Index; Cholesterol, LDL; Cluster Analysis; Dia

2004
Uric acid or 1-methyl uric acid in the urinary bladder increases serum glucose, insulin, true triglyceride, and total cholesterol levels in Wistar rats.
    TheScientificWorldJournal, 2003, Oct-05, Volume: 3

    Topics: Administration, Intravesical; Animals; Blood Glucose; Cholesterol; Female; Hypercholesterolemia; Hyp

2003
Treatment of massive hypertriglyceridemia resistant to PUFA and fibrates: a possible role for the coenzyme Q10?
    BioFactors (Oxford, England), 2005, Volume: 23, Issue:1

    Topics: Adult; Blood Pressure; Cholesterol; Coenzymes; Creatinine; Diet; Drug Resistance; Fatty Acids, Omega

2005
Gallstone disease in non-alcoholic fatty liver: prevalence and associated factors.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:8

    Topics: Age Factors; Apolipoproteins B; Biopsy; Cholecystolithiasis; Cholesterol; Fatty Liver; Female; Gallb

2005
[Association between serum uric acid and triglyceride in a Chinese community].
    Zhonghua nei ke za zhi, 2005, Volume: 44, Issue:9

    Topics: Adult; China; Cross-Sectional Studies; Female; Humans; Hypertriglyceridemia; Logistic Models; Male;

2005
The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China.
    The Journal of rheumatology, 2006, Volume: 33, Issue:7

    Topics: Adult; Aged; Alcohol Drinking; China; Cross-Sectional Studies; Female; Gout; Humans; Hypercholestero

2006
Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:10

    Topics: Allopurinol; Animals; Blood Pressure; Body Weight; Diuretics; Fructose; Gout Suppressants; Hydrochlo

2007
Serum uric acid level as an independent component of the metabolic syndrome in type 2 diabetic blacks.
    Nigerian journal of clinical practice, 2007, Volume: 10, Issue:2

    Topics: Adult; Aged; Black People; Diabetes Mellitus, Type 2; Epidemiologic Studies; Female; Humans; Hypertr

2007
Anatomical relationship between traditional acupuncture point ST 36 and Omura's ST 36 (True ST 36) with their therapeutic effects: 1) inhibition of cancer cell division by markedly lowering cancer cell telomere while increasing normal cell telomere, 2) im
    Acupuncture & electro-therapeutics research, 2007, Volume: 32, Issue:1-2

    Topics: Acupuncture; Acupuncture Points; Blood Cell Count; Blood Glucose; C-Reactive Protein; Cardiovascular

2007
Serum uric acid levels and risk of metabolic syndrome in healthy adults.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2008, Volume: 14, Issue:3

    Topics: Adult; Biomarkers; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertriglyceridemia; Hype

2008
Increased VLDL levels and diminished renal excretion of uric acid in hyperuricaemic-hypertriglyceridaemic patients.
    British journal of rheumatology, 1995, Volume: 34, Issue:10

    Topics: Adult; Apolipoproteins B; Cholesterol, HDL; Humans; Hypertriglyceridemia; Lipoproteins, VLDL; Male;

1995
A metabolic syndrome in whites and African-Americans. The Atherosclerosis Risk in Communities baseline study.
    Diabetes care, 1996, Volume: 19, Issue:5

    Topics: Arteriosclerosis; Black People; Cholesterol, HDL; Cluster Analysis; Diabetes Mellitus; Ethnicity; Fe

1996
[Arterial hypertension and diabetes in Ouagadougou (Burkina Faso)].
    Bulletin de la Societe de pathologie exotique (1990), 1996, Volume: 89, Issue:1

    Topics: Adult; Aged; Burkina Faso; Diabetes Complications; Diabetic Angiopathies; Female; Humans; Hyperchole

1996
High blood pressure of hypertriglyceridaemic rats is related to metabolic disturbances.
    Physiological research, 1995, Volume: 44, Issue:6

    Topics: Animals; Blood Pressure; Crosses, Genetic; Female; Hypertension; Hypertriglyceridemia; Kidney; Lipid

1995
Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia.
    Acta biologica Hungarica, 1997, Volume: 48, Issue:3

    Topics: Apolipoprotein A-I; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female;

1997
[Risk factors and etiology of retinal vein occlusion].
    La Tunisie medicale, 1995, Volume: 73, Issue:2

    Topics: Adult; Age Factors; Aged; Arteriosclerosis; Behcet Syndrome; Coronary Disease; Diabetes Complication

1995
Clustering of cardiovascular risk factors in hyperinsulinemia in Japanese without diabetes.
    Diabetes research and clinical practice, 1998, Volume: 40, Issue:3

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hyperinsulinism; Hypertensio

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.
    Diabetes, 1998, Volume: 47, Issue:10

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Homeos

1998
Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity.
    Diabetes & metabolism, 1998, Volume: 24, Issue:4

    Topics: Adult; Belgium; Body Mass Index; Body Weight; Cholesterol; Cholesterol, HDL; Cohort Studies; Comorbi

1998
Hyperlipidaemia in hyperuricaemia and gout.
    Annals of the rheumatic diseases, 1998, Volume: 57, Issue:9

    Topics: Gout; Humans; Hyperinsulinism; Hypertriglyceridemia; Insulin Resistance; Uric Acid

1998
Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Female; Glomerulonephritis, IGA; Humans; Hypercholesterolemia; Hyper

2000
Hypertriglyceridaemia and hyperuricaemia in IgA nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:3

    Topics: Glomerulonephritis, IGA; Humans; Hypertriglyceridemia; Middle Aged; Uric Acid

2001
Biochemical profile of idiopathic uric acid nephrolithiasis.
    Kidney international, 2001, Volume: 60, Issue:2

    Topics: Adult; Female; Gout; Humans; Hydrogen-Ion Concentration; Hypertriglyceridemia; Kidney Calculi; Male;

2001
Hyperuricemia-hyperlipemia association in the absence of obesity and alcohol abuse.
    Clinical rheumatology, 1990, Volume: 9, Issue:1

    Topics: Adult; Alcohol Drinking; Cholesterol; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; H

1990
Relationship between hypertriglyceridemia and uric acid production in primary gout.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:7

    Topics: Alcohol Drinking; Cholesterol; Cholesterol, HDL; Gout; Humans; Hypertriglyceridemia; Male; Reference

1989