Page last updated: 2024-10-20

uric acid and Hyperoxia

uric acid has been researched along with Hyperoxia in 9 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.

Research Excerpts

ExcerptRelevanceReference
"Inosine treatment during hyperoxia also reduced the proportion of AEC2 in S and G2/M phases of the cell cycle and increased levels of the DNA repair enzyme 8-oxoguanine DNA glycosylase."5.33In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. ( Barsky, L; Buckley, S; Warburton, D; Weinberg, K, 2005)
"Inosine treatment during hyperoxia also reduced the proportion of AEC2 in S and G2/M phases of the cell cycle and increased levels of the DNA repair enzyme 8-oxoguanine DNA glycosylase."1.33In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. ( Barsky, L; Buckley, S; Warburton, D; Weinberg, K, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vukovic, J2
Modun, D2
Budimir, D2
Sutlovic, D2
Salamunic, I2
Zaja, I1
Boban, M2
Pace, PW1
Yao, LJ1
Wilson, JX1
Possmayer, F1
Veldhuizen, RA1
Lewis, JF1
Krnic, M1
Gunjaca, G1
Jajic, I1
Kozina, B1
HALE, HB2
WILLIAMS, EW2
ANDERSON, JE2
ELLIS, JP2
Schmidt, R1
Schäfer, C1
Luboeinski, T1
Löckinger, A1
Hermle, G1
Grimminger, F1
Seeger, W1
Ghofrani, A1
Schütte, H1
Günther, A1
Buckley, S1
Barsky, L1
Weinberg, K1
Warburton, D1
Vento, G1
Mele, MC1
Mordente, A1
Romagnoli, C1
Matassa, PG1
Zecca, E1
Zappacosta, B1
Persichilli, S1
Jaensch, S1
Cullen, L1
Morton, L1
Raidal, SR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Differences Between Insulin Glargine U300 and Insulin Degludec U100 in Impact on the Glycaemic Variability, Oxidative Stress, Arterial Stiffness and the Lipid Profiles in Insulin naïve Patients Suffering From Type Two Diabetes Mellitus[NCT04692415]Phase 425 participants (Actual)Interventional2018-12-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for uric acid and Hyperoxia

ArticleYear
Acute, food-induced moderate elevation of plasma uric acid protects against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans.
    Atherosclerosis, 2009, Volume: 207, Issue:1

    Topics: Acute Disease; Adult; Beverages; Biomarkers; Brachial Artery; Cross-Over Studies; Elasticity; Ethano

2009

Other Studies

8 other studies available for uric acid and Hyperoxia

ArticleYear
The effects of hyperoxia exposure on lung function and pulmonary surfactant in a rat model of acute lung injury.
    Experimental lung research, 2009, Volume: 35, Issue:5

    Topics: Acute Lung Injury; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Bronchoalveolar Lavage Fluid; D

2009
Comparison of acute effects of red wine, beer and vodka against hyperoxia-induced oxidative stress and increase in arterial stiffness in healthy humans.
    Atherosclerosis, 2011, Volume: 218, Issue:2

    Topics: Adult; Alcoholic Beverages; Alcohols; Antioxidants; Beer; Cross-Over Studies; Humans; Hyperoxia; Lip

2011
ENDOCRINE AND METABOLIC EFFECTS OF SHORT-DURATION HYPEROXIA. TECHN DOCUM REP SAM-TDR-64-6.
    Technical documentary report. United States. Air Force. Systems Command. Electronic Systems Division, 1964, Volume: 94

    Topics: Adrenal Cortex Hormones; Biomedical Research; Body Fluids; Creatine; Creatinine; Epinephrine; Humans

1964
ENDOCRINE AND METABOLIC EFFECTS OF SHORT-DURATION HYPEROXIA.
    Aerospace medicine, 1964, Volume: 35

    Topics: Adrenal Cortex Hormones; Aerospace Medicine; Biomedical Research; Cortisone; Creatine; Creatinine; E

1964
Increase in alveolar antioxidant levels in hyperoxic and anoxic ventilated rabbit lungs during ischemia.
    Free radical biology & medicine, 2004, Jan-01, Volume: 36, Issue:1

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Hyperoxia; Hypoxia; Ischemia; L-Lactate Dehydro

2004
In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Cycle; Cells, Cultured; Cytoprotection; DNA Damage; DNA

2005
High total antioxidant activity and uric acid in tracheobronchial aspirate fluid of preterm infants during oxidative stress: an adaptive response to hyperoxia?
    Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:3

    Topics: Antioxidants; Bronchi; Exudates and Transudates; Feasibility Studies; Female; Humans; Hyperoxia; Inf

2000
Normobaric hyperoxic stress in budgerigars: non-enzymic antioxidants.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 128, Issue:2

    Topics: Animals; Antioxidants; Carotenoids; Glutathione; Hyperoxia; Lung; Oxygen; Parrots; Uric Acid; Vitami

2001