Page last updated: 2024-10-20

uric acid and Hyperlipoproteinemia

uric acid has been researched along with Hyperlipoproteinemia in 34 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Fenofibrate, a phenoxyacid derivative, given at daily dose of 300mg during 1 year following a single blind design, lowered significantly serum triglycerides and total cholesterol in patients various types of hyperlipoproteinemias (IIa, IV, V), fibrate significantly reduced plasma uric acid."9.05Hypolipidemic and hypouricemic action of fenofibrate in various types of hyperlipoproteinemias. ( Desager, JP; Harvengt, C; Heller, F, 1980)
" In the study reported, the effect of 2-acetamidoethyl-(p-chlorophenyl)-(m-trifluoro-methylphenoxy)-acetate (halofenate) was investigated in 14 patients suffering from hyperlipoproteinemia type IV and hyperuricemia."9.04[Effect of halofenate on triglyceride and uric acid levels, coagulation and platelet behaviour in patients with hyperlipoproteinemia type IV and hyperuricemia (author's transl)]. ( Hehl, FJ; Kuntzen, O; Walter, E; Zimmermann, R, 1978)
" In type IIa etofylline clofibrate shows a good effect on total cholesterol and on the cholesterol fractions, both with regard to the collective treated and to the low dosage of 750 mg/d etofylline clofibrate compared to the usual dosage of 1500 mg clofibrate."5.26[On the effect of etofylline clofibrate on serum lipids and lipoproteins in patients with hyperlipoproteinemia of various degrees (author's transl)]. ( Hausmann, L; Mühlfellner, G; Mühlfellner, O; Schneider, J; Schubotz, R, 1980)
"Fenofibrate is a potent hypolipemic agent, widely used in patients with mild to severe renal failure in whom hyperlipoproteinemia is frequent."5.09[Fenofibrate increases blood creatinine, but does not change the glomerular filtration rate in patients with mild renal insufficiency]. ( Achard, JM; el Esper, N; Fournier, A; Hottelart, C; Pruna, A, 1999)
"Fenofibrate, a phenoxyacid derivative, given at daily dose of 300mg during 1 year following a single blind design, lowered significantly serum triglycerides and total cholesterol in patients various types of hyperlipoproteinemias (IIa, IV, V), fibrate significantly reduced plasma uric acid."5.05Hypolipidemic and hypouricemic action of fenofibrate in various types of hyperlipoproteinemias. ( Desager, JP; Harvengt, C; Heller, F, 1980)
" In the study reported, the effect of 2-acetamidoethyl-(p-chlorophenyl)-(m-trifluoro-methylphenoxy)-acetate (halofenate) was investigated in 14 patients suffering from hyperlipoproteinemia type IV and hyperuricemia."5.04[Effect of halofenate on triglyceride and uric acid levels, coagulation and platelet behaviour in patients with hyperlipoproteinemia type IV and hyperuricemia (author's transl)]. ( Hehl, FJ; Kuntzen, O; Walter, E; Zimmermann, R, 1978)
"Twenty-two patients suffering from hyperlipidemia and receiving therapy consisting of a lipid-lowering diet and clofibrate (1 g X 2) were in addition given colestipol hydrochloride (5 g X 3) (Colestid, Upjohn) in a randomized, cross-over study for 2 periods of 6 weeks."2.65The effects of colestipol when combined with clofibrate in the treatment of severe hyperlipidemia. Short-term and long-term studies. ( Boberg, J; Hellsing, K; Lithell, H; Vessby, B, 1980)
"Patients with NIDDM had 11% increase of high density lipoprotein-cholesterol (HDL-C) level at the end of the first, and 18% increase at the end of the second month, while patients with primary hyperlipoproteinaemia did not change significantly."1.30Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia. ( Balogh, Z; Boda, J; Kárpáti, L; Kovács, P; Leövey, A; Paragh, G; Szabó, J, 1997)
" In type IIa etofylline clofibrate shows a good effect on total cholesterol and on the cholesterol fractions, both with regard to the collective treated and to the low dosage of 750 mg/d etofylline clofibrate compared to the usual dosage of 1500 mg clofibrate."1.26[On the effect of etofylline clofibrate on serum lipids and lipoproteins in patients with hyperlipoproteinemia of various degrees (author's transl)]. ( Hausmann, L; Mühlfellner, G; Mühlfellner, O; Schneider, J; Schubotz, R, 1980)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199029 (85.29)18.7374
1990's3 (8.82)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Yu, X1
Wang, T1
Huang, S1
Zeng, P1
Kaffarnik, H1
Schneider, J2
Schubotz, R2
Zöfel, P1
Hausmann, L2
Goebel, KM1
Barats, IS2
Makarova, VIu1
Dumas, JR1
Krajnc, I1
Kerum, G1
Muggeo, M1
Calabrò, A1
Businaro, V1
Moghetti, P1
Padovan, D1
Crepaldi, G1
Reinhardt, K1
Wagner, M1
Lithell, H1
Vessby, B1
Boberg, J1
Hellsing, K1
Haller, H1
Jaross, W1
Hanefeld, M1
Fiegel, G1
Heidelmann, G2
Thiele, P3
Schröder, HE4
Mühlfellner, G1
Mühlfellner, O1
Lohse, R1
Böhm, WD1
Harvengt, C1
Heller, F1
Desager, JP1
Grabner, W1
Worlicek, H1
Beenken, O1
Kopperschläger, G1
Otto, W1
Häntzschel, H1
Pietruschka, WD1
Weinhold, D1
Schwartzkopff, W1
Schilling, A1
Calder, D1
Schneider, H2
Ziegelasch, HJ2
Eggenberger, M1
Paragh, G1
Balogh, Z1
Boda, J1
Kovács, P1
Kárpáti, L1
Szabó, J1
Leövey, A1
Hottelart, C1
el Esper, N1
Achard, JM1
Pruna, A1
Fournier, A1
Rohrbach, JM1
Kleiser, N1
Kaufmann-Fechner, J1
Lisch, W1
Kuntzen, O1
Hehl, FJ1
Walter, E1
Zimmermann, R1
de Oliveira, JM1
Schwandt, P1
Richter, WO1
Kullich, W1
Ulreich, A1
Klein, G1
Seidel, D1
Cremer, P1
Segers, AM1
de Forteza, IE1
Conforti, FY1
Abulafia, J1
Wallace, RB1
Pomrehn, P1
Heiss, G1
Chambless, LE1
Johnson, N1
Patten, R1
Lippel, K1
Rifkind, BM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005128]0 participants Observational1972-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for uric acid and Hyperlipoproteinemia

ArticleYear
Complete destruction of both femoral heads following idiopathic necrosis of the femoral heads in a diabetic patient with hyperuricemia and hyperlipoproteinemia.
    Archives of orthopaedic and traumatic surgery. Archiv fur orthopadische und Unfall-Chirurgie, 1980, Volume: 96, Issue:2

    Topics: Aged; Angiography; Diabetes Complications; Femur Head Necrosis; Gout; Heel; Hip; Humans; Hyperlipopr

1980
[Alcohol and lipid metabolism].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Aug-15, Volume: 36, Issue:16

    Topics: Alcohol Oxidoreductases; Alcoholism; Anemia, Hemolytic; Ethanol; Fatty Acids, Nonesterified; Humans;

1981
[Hypertension, Type II diabetes mellitus and macroangiopathy: risk factors and their association].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, Feb-01, Volume: 83, Issue:5

    Topics: Albuminuria; Alcohol Drinking; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Exercise; Female; H

1994
[Corneal ring opacity (Ascher ring)--a case report].
    Klinische Monatsblatter fur Augenheilkunde, 2001, Volume: 218, Issue:4

    Topics: Cornea; Corneal Opacity; Diagnosis, Differential; Humans; Hyperlipoproteinemias; Male; Middle Aged;

2001
[Genetic metabolic defects in adults].
    Der Internist, 1989, Volume: 30, Issue:9

    Topics: Arteriosclerosis; Gout; Humans; Hyperlipoproteinemias; Phenotype; Risk Factors; Uric Acid

1989

Trials

5 trials available for uric acid and Hyperlipoproteinemia

ArticleYear
The effects of colestipol when combined with clofibrate in the treatment of severe hyperlipidemia. Short-term and long-term studies.
    Atherosclerosis, 1980, Volume: 37, Issue:2

    Topics: Alkaline Phosphatase; Cholesterol; Clofibrate; Colestipol; Drug Therapy, Combination; Female; Humans

1980
[Therapeutic effect of etofyllinclofibrate in disordered lipid and uric acid metabolism].
    Die Medizinische Welt, 1982, Mar-05, Volume: 33, Issue:9

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Clofibrate; Female; Humans; Hy

1982
Hypolipidemic and hypouricemic action of fenofibrate in various types of hyperlipoproteinemias.
    Artery, 1980, Volume: 7, Issue:1

    Topics: Adult; Fenofibrate; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipids; Middle Aged; Propio

1980
[Fenofibrate increases blood creatinine, but does not change the glomerular filtration rate in patients with mild renal insufficiency].
    Nephrologie, 1999, Volume: 20, Issue:1

    Topics: Aged; Creatinine; Cross-Over Studies; Female; Fenofibrate; Glomerular Filtration Rate; Humans; Hyper

1999
[Effect of halofenate on triglyceride and uric acid levels, coagulation and platelet behaviour in patients with hyperlipoproteinemia type IV and hyperuricemia (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:12

    Topics: Adult; Blood Coagulation; Cholesterol; Double-Blind Method; Glycolates; Halofenate; Humans; Hyperlip

1978

Other Studies

24 other studies available for uric acid and Hyperlipoproteinemia

ArticleYear
Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysis.
    Journal of human genetics, 2021, Volume: 66, Issue:5

    Topics: Age Factors; Causality; Cholesterol; Dyslipidemias; Genome-Wide Association Study; Gout; Humans; Hyp

2021
Long-term treatment of hyperlipoproteinemia with etofibrate: clinical observations.
    Artery, 1980, Volume: 8, Issue:6

    Topics: Adult; Aged; Cholesterol; Clofibrate; Clofibric Acid; Creatine Kinase; Female; gamma-Glutamyltransfe

1980
[Hyperuricemia in ischemic heart disease].
    Kardiologiia, 1984, Volume: 24, Issue:8

    Topics: Adult; Body Weight; Coronary Disease; Diuretics; Gout; Humans; Hyperlipoproteinemias; Hypertension;

1984
[State of lipid and purine metabolism in children with a family history of ischemic heart disease].
    Pediatriia, 1984, Issue:11

    Topics: Adolescent; Adult; Child; Child, Preschool; Coronary Disease; Humans; Hyperlipoproteinemias; Infant;

1984
[Protein overload, hyperucemia, gout].
    Soins; la revue de reference infirmiere, 1983, Issue:406

    Topics: Adult; Diet; Female; Gout; Humans; Hyperlipoproteinemias; Male; Middle Aged; Uric Acid

1983
[Association of risk factors in patients with hyperuricemia].
    Reumatizam, 1983, Volume: 30, Issue:5-6

    Topics: Blood Glucose; Body Weight; Female; Humans; Hyperlipoproteinemias; Lipids; Male; Uric Acid

1983
[Correlation of metabolic and hemorrheological parameters in diabetes and hyperlipidemia].
    La Ricerca in clinica e in laboratorio, 1983, Volume: 13 Suppl 3

    Topics: Blood Viscosity; Cholesterol; Cholesterol, HDL; Diabetes Mellitus; Diabetic Angiopathies; Erythrocyt

1983
[Extraarticular diseases and findings in gout].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Jul-01, Volume: 37, Issue:13

    Topics: Arteriosclerosis; Diabetes Complications; Female; Gout; Humans; Hyperlipoproteinemias; Hypertension;

1982
[Prognosis for disorders of purine metabolism].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Jul-01, Volume: 37, Issue:13

    Topics: Age Factors; Arterial Occlusive Diseases; Diabetes Mellitus; Germany, East; Gout; Humans; Hyperlipop

1982
[Prevention and therapy of disorders of purine metabolism].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1982, Jul-01, Volume: 37, Issue:13

    Topics: Arteriosclerosis; Diabetes Mellitus; Gout; Gout Suppressants; Humans; Hyperlipoproteinemias; Metabol

1982
[Dyslipoproteinemia and hyperuricemia in podagra and urinary calculi].
    Terapevticheskii arkhiv, 1982, Volume: 54, Issue:10

    Topics: Adult; Arteriosclerosis; Cholesterol; Foot Diseases; Gout; Humans; Hyperlipoproteinemias; Hypolipopr

1982
[On the effect of etofylline clofibrate on serum lipids and lipoproteins in patients with hyperlipoproteinemia of various degrees (author's transl)].
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:11b

    Topics: Cholesterol; Clofibrate; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipids; Lipoproteins;

1980
[Incidence of metabolic disorders in patients with recurrent urinary calculi].
    Zeitschrift fur Urologie und Nephrologie, 1981, Volume: 74, Issue:3

    Topics: Adult; Aged; Calcium Oxalate; Creatinine; Diabetes Complications; Electrolytes; Female; Humans; Hydr

1981
[The relation between gout and diabetes mellitus].
    Fortschritte der Medizin, 1981, Aug-06, Volume: 99, Issue:29

    Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Gout; Humans; Hyperlipoproteinemias; Metab

1981
[Comparative biochemical studies in asymptomatic hyperuricemia and manifest gout with special reference to renal change].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, May-01, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Creatinine; Electrophoresis, Polyacrylamide Gel; Gout; Humans; Hyperlipoproteinem

1981
[Therapy of hyperlipoproteinemia type IIa, IIb and IV with Etofibrate retard].
    Die Medizinische Welt, 1980, Apr-04, Volume: 31, Issue:14

    Topics: Blood Glucose; Cholesterol; Clofibrate; Creatinine; Delayed-Action Preparations; Humans; Hyperlipopr

1980
[Associated cardiovascular factors of risk in borderline-diabetes (author's transl)].
    Zeitschrift fur Alternsforschung, 1980, Volume: 35, Issue:2

    Topics: Adult; Aged; Cholesterol; Diabetes Complications; Female; Glucose Tolerance Test; Humans; Hyperlipop

1980
Treatment possibility of hypercholesterolaemia associated with hypertriglyceridaemia.
    Acta biologica Hungarica, 1997, Volume: 48, Issue:3

    Topics: Apolipoprotein A-I; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female;

1997
[The cardiovascular risk profile of the borderline diabetic].
    Zeitschrift fur arztliche Fortbildung, 1979, Apr-15, Volume: 73, Issue:8

    Topics: Adult; Aged; Cardiovascular Diseases; Coronary Disease; Diabetes Complications; Humans; Hypercholest

1979
[Coronary risk factors].
    Arquivos brasileiros de cardiologia, 1979, Volume: 33, Issue:1

    Topics: Coronary Disease; Diabetes Complications; Diet; Female; Humans; Hypercholesterolemia; Hyperlipoprote

1979
[Hyperlipoproteinemia in primary gout and asymptomatic hyperuricemia].
    Wiener medizinische Wochenschrift (1946), 1988, May-31, Volume: 138, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cholesterol; Creatinine; Gout; Humans; Hyperlipoproteine

1988
Influence of known risk factors on the lipoprotein profile.
    Monographs on atherosclerosis, 1986, Volume: 14

    Topics: Adult; Alcohol Drinking; Blood Glucose; Body Weight; Humans; Hyperlipoproteinemias; Hypolipoproteine

1986
[Cellulite].
    Medicina cutanea ibero-latino-americana, 1985, Volume: 13, Issue:6

    Topics: Adipose Tissue; Carbohydrate Metabolism; Cellulitis; Cholesterol; Female; Galactorrhea; Humans; Hype

1985
Alterations in clinical chemistry levels associated with the dyslipoproteinemias. The Lipid Research Clinics Program Prevalence Study.
    Circulation, 1986, Volume: 73, Issue:1 Pt 2

    Topics: Adult; Blood Glucose; Creatinine; Diabetes Mellitus; Dysgammaglobulinemia; Female; Humans; Hyperlipo

1986