uric acid has been researched along with Hyperinsulinism in 51 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin and uric acid were shown affect the prevalence of Metabolic Syndrome (MetS), but no studies examine their interaction." | 7.88 | Low serum uric acid concentration augments insulin effects on the prevalence of metabolic syndrome. ( Gonzalez-Mejia, ME; Pérez-Fuentes, R; Porchia, LM; Ruiz-Vivanco, G; Torres-Rasgado, E, 2018) |
| "We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects." | 7.74 | Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database. ( Bonadonna, RC; Bonora, E; Capaldo, B; De Mattia, G; Del Prato, S; Frittitta, L; Frontoni, S; Leonetti, F; Luzi, L; Marchesini, G; Marini, MA; Natali, A; Paolisso, G; Perin, PC; Piatti, PM; Pujia, A; Solini, A; Vettor, R, 2008) |
| "We performed polysomnography and hyperinsulinemic euglycemic clamp studies and measured serum leptin in three patients with LBS and in six patients with "simple" truncal obesity, matched for sex and body mass index (LBS group, 36." | 7.71 | Insulin resistance, hyperleptinemia, and obstructive sleep apnea in Launois-Bensaude syndrome. ( Ficker, JH; Fuchs, FS; Hahn, EG; Harsch, IA; Konturek, PC; Lohmann, T; Schahin, SP, 2002) |
| "In contrast, hyperinsulinemia caused a significant decrease in the urinary excretion of uric acid (2." | 6.68 | Effect of insulin on renal sodium and uric acid handling in essential hypertension. ( Bianchi, S; Bigazzi, R; Ciociaro, D; Ferrannini, E; Frascerra, S; Galvan, AQ; Muscelli, E; Natali, A; Sironi, AM, 1996) |
| "Uric acid nephrolithiasis primarily results from low urinary pH, which increases the concentration of the insoluble undissociated uric acid, causing formation of both uric acid and mixed uric acid/calcium oxalate stones." | 5.32 | The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. ( Abate, N; Cabo-Chan, AV; Chandalia, M; Moe, OW; Sakhaee, K, 2004) |
| "Insulin and uric acid were shown affect the prevalence of Metabolic Syndrome (MetS), but no studies examine their interaction." | 3.88 | Low serum uric acid concentration augments insulin effects on the prevalence of metabolic syndrome. ( Gonzalez-Mejia, ME; Pérez-Fuentes, R; Porchia, LM; Ruiz-Vivanco, G; Torres-Rasgado, E, 2018) |
| "Increased serum uric acid (UA) is associated with incident heart failure (HF)." | 3.76 | Effect of serum insulin on the association between hyperuricemia and incident heart failure. ( Aban, IB; Ahmed, A; Ahmed, MI; Aronow, WS; Desai, RV; Filippatos, GS; Fonarow, GC; White, M, 2010) |
| "We evaluated whether hyperinsulinemia and/or insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects." | 3.74 | Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database. ( Bonadonna, RC; Bonora, E; Capaldo, B; De Mattia, G; Del Prato, S; Frittitta, L; Frontoni, S; Leonetti, F; Luzi, L; Marchesini, G; Marini, MA; Natali, A; Paolisso, G; Perin, PC; Piatti, PM; Pujia, A; Solini, A; Vettor, R, 2008) |
| "Anthropometric parameters, blood lipid spectrum, levels of glucose, uric acid (UA), immunoreactive insulin, HOMA index were studied in 55 male patients with gout (mean age 50." | 3.72 | [Insulin resistance syndrome in patients with gout and its influence on formation of clinical characteristics of the disease]. ( Barskova, VG; Eliseev, MS; Iakunina, IA; Il'inykh, EV; Nasonov, EL; Zilov, AV, 2004) |
| "Stratified analyses revealed that (1) serum uric acid levels were positively associated with hyperinsulinemia and HOMA-insulin resistance in both men and women after adjusting for hypertriglyceridemia, hypertension, obesity, and plasma glucose levels; and (2) serum uric acid levels were more strongly associated with hyperinsulinemia and plasma glucose levels in women than in men." | 3.71 | Gender differences in the relationships of serum uric acid with fasting serum insulin and plasma glucose in patients without diabetes. ( Chou, P; Lin, HY; Lin, KC; Tsai, ST, 2001) |
| "We performed polysomnography and hyperinsulinemic euglycemic clamp studies and measured serum leptin in three patients with LBS and in six patients with "simple" truncal obesity, matched for sex and body mass index (LBS group, 36." | 3.71 | Insulin resistance, hyperleptinemia, and obstructive sleep apnea in Launois-Bensaude syndrome. ( Ficker, JH; Fuchs, FS; Hahn, EG; Harsch, IA; Konturek, PC; Lohmann, T; Schahin, SP, 2002) |
| " The high prevalence and severity of metabolic disturbances associated with the insulin resistance syndrome (hyperglycaemia, hyperinsulinaemia, decreased HDL cholesterol, hypertriglyceridaemia, elevated fibrinogen levels and hyperuricaemia) before gastroplasty were significantly decreased after weight loss." | 3.70 | Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity. ( Desaive, C; Dewe, W; Gielen, JE; Lefebvre, PJ; Luyckx, FH; Scheen, AJ, 1998) |
| "The aim of the present research was to compare the uric acid, sodium and potassium excretions among patients with mild preeclampsia and normotensive pregnancy and to determine their behavior towards an acute physiologic state of hyperglycemia-hyperinsulinemia." | 3.70 | [Excretion of uric aid, sodium, and potassium in preeclampsia patients and its behavior in acute hyperglycemia-hyperinsulinemia]. ( González-Ortiz, M; Grover-Páez, F; Martínez-Abundis, E; Vera-Hernández, A, 1999) |
| "The major aim of this study was to compare various aspects of carbohydrate, insulin, and lipoprotein metabolism, serum uric acid concentration, and blood pressure in normal subjects stratified on the basis of both plasma insulin concentration and degree of obesity." | 3.69 | Hyperinsulinaemia, obesity, and syndrome X. ( Bonini, L; Dall'Aglio, E; Fantuzzi, M; Passeri, M; Reaven, GM; Zavaroni, I, 1994) |
| " Body mass index (BMI), waist/hip ratio (WHR), blood pressure (BP); oral glucose tolerance test (OGTT) with measurement of serum glucose, insulin and C-peptide every 30 min for 2 h, fasting serum cholesterol, triglycerides and uric acid, areas under curve (AUC) of glucose and insulin, insulin/glucose ratio and insulin sensitivity index were calculated." | 3.69 | Hyperinsulinemia in patients with coronary heart disease in absence of overt risk factors. ( Almazán, A; Ariza, CR; Frati, AC; Gómez, G, 1997) |
| " We investigated the impact of mycoprotein ingestion, in a dose-response manner, on acute postprandial hyperaminoacidaemia and hyperinsulinaemia." | 2.84 | Mycoprotein represents a bioavailable and insulinotropic non-animal-derived dietary protein source: a dose-response study. ( Bowtell, JL; Dunlop, MV; Finnigan, TJA; Kilroe, SP; Salmon, DL; Wall, BT, 2017) |
| "In contrast, hyperinsulinemia caused a significant decrease in the urinary excretion of uric acid (2." | 2.68 | Effect of insulin on renal sodium and uric acid handling in essential hypertension. ( Bianchi, S; Bigazzi, R; Ciociaro, D; Ferrannini, E; Frascerra, S; Galvan, AQ; Muscelli, E; Natali, A; Sironi, AM, 1996) |
| "In contrary, the so-called type 2 diabetes is a multifactorial, often hyperinsulinaemic condition of insulin resistance and it occurs mainly in the adults." | 2.40 | [From type 2 diabetes to metabolic X syndrome]. ( Pogátsa, G, 1999) |
| "Insulin resistance/hyperinsulinemia, in turn, is associated with a series of hypertensiogenic and atherogenic side effects, aggravating the individual components of the metabolic syndrome." | 2.39 | [The metabolic syndrome. Pathophysiologic causes, diagnosis, therapy]. ( Rett, K; Standl, E; Wicklmayr, M, 1994) |
| "The baseline hyperinsulinemia-follow-up hyperuricemia group showed the highest incidence rate of T2DM (27." | 1.91 | Bidirectional temporal relationships between uric acid and insulin and their joint impact on incident diabetes. ( Bazzano, L; Chen, W; Fan, L; He, J; Li, S; Sun, D; Wang, X; Yan, Y; Zhang, T, 2023) |
| "Metabolic syndrome and hyperinsulinemia are associated with hyperuricemia." | 1.91 | Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis. ( Choi, HK; Leask, MP; Mandal, AK; Merriman, TR; Mount, DB; Sumpter, NA, 2023) |
| "Risk of cancer is increased in conditions associated with insulin resistance, but this could be secondary to subclinical inflammation." | 1.36 | Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. ( Godsland, IF; Johnston, DG; Loh, WJ; North, BV, 2010) |
| "In addition, hyperinsulinemia-induced renal magnesium wasting also may be a contributory factor." | 1.33 | Disturbances of phosphate metabolism: another feature of metabolic syndrome. ( Bairaktari, E; Elisaf, M; Kalaitzidis, R; Siamopoulos, KC; Tsimihodimos, V, 2005) |
| "Weight gain is a known side effect of valproate (VPA) therapy, which is associated with hyperinsulinemia and polycystic ovary-like syndrome and unfavorable lipid changes in women." | 1.33 | Insulin-related metabolic changes during treatment with valproate in patients with epilepsy. ( Isojärvi, J; Knip, M; Pakarinen, A; Pylvänen, V, 2006) |
| "Uric acid nephrolithiasis primarily results from low urinary pH, which increases the concentration of the insoluble undissociated uric acid, causing formation of both uric acid and mixed uric acid/calcium oxalate stones." | 1.32 | The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. ( Abate, N; Cabo-Chan, AV; Chandalia, M; Moe, OW; Sakhaee, K, 2004) |
| "In conclusion, hyperinsulinemia, as well as obesity, hyperuricemia, and hypertriglyceridemia were associated with hypertension in Japanese-Americans." | 1.31 | Hyperinsulinemia for the development of hypertension: data from the Hawaii-Los Angeles-Hiroshima Study. ( Egusa, G; Imazu, M; Kohno, N; Okubo, M; Sumii, K; Toyofuku, M; Yamakido, M; Yamamoto, H, 2001) |
| "Compared with saline, physiological hyperinsulinemia increased femoral artery flow (1." | 1.31 | Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow. ( Barrett, EJ; Clark, AD; Clark, MG; Dawson, D; Lindner, JR; Rattigan, S; Vincent, MA, 2002) |
| "Hyperinsulinemia was related to the development of ST-T abnormalities in ECGs in the absence of the development of clinical signs of atherosclerosis, independent of blood pressure and other risk factors in men and women with mild glucose intolerance." | 1.30 | Hyperinsulinemia and the development of ST-T electrocardiographic abnormalities. An 11-year follow-up study. ( Adachi, H; Crow, RS; Hashimoto, R; Imaizumi, T; Jacobs, DR; Tsuruta, M, 1997) |
| "13 patients had combination of hyperinsulinemia with obesity, dyslipidemia, arterial hypertension." | 1.30 | [Urate affection of kidneys and metabolic disturbances in hypertensive patients]. ( Anikina, SA; Balkarov, IM; Donskov, AS; Fadina, ZM; Feofanova, ID; Golub', GV; Goncharov, VS; Saltykova, NG, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (13.73) | 18.7374 |
| 1990's | 20 (39.22) | 18.2507 |
| 2000's | 13 (25.49) | 29.6817 |
| 2010's | 9 (17.65) | 24.3611 |
| 2020's | 2 (3.92) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, Y | 1 |
| Wang, X | 1 |
| Li, S | 1 |
| Sun, D | 1 |
| Fan, L | 1 |
| Bazzano, L | 1 |
| He, J | 1 |
| Zhang, T | 1 |
| Chen, W | 1 |
| Mandal, AK | 1 |
| Leask, MP | 1 |
| Sumpter, NA | 1 |
| Choi, HK | 1 |
| Merriman, TR | 1 |
| Mount, DB | 1 |
| Dunlop, MV | 1 |
| Kilroe, SP | 1 |
| Bowtell, JL | 1 |
| Finnigan, TJA | 1 |
| Salmon, DL | 1 |
| Wall, BT | 1 |
| Porchia, LM | 1 |
| Gonzalez-Mejia, ME | 1 |
| Torres-Rasgado, E | 1 |
| Ruiz-Vivanco, G | 1 |
| Pérez-Fuentes, R | 1 |
| Olaniyi, KS | 1 |
| Olatunji, LA | 1 |
| Li, F | 2 |
| Xia, K | 2 |
| Li, C | 1 |
| Yang, T | 2 |
| Cui, Y | 1 |
| Bu, H | 1 |
| Ma, X | 1 |
| Zhao, S | 1 |
| Li, X | 1 |
| Lu, S | 1 |
| Loh, WJ | 1 |
| North, BV | 1 |
| Johnston, DG | 1 |
| Godsland, IF | 1 |
| Desai, RV | 1 |
| Ahmed, MI | 1 |
| Fonarow, GC | 1 |
| Filippatos, GS | 1 |
| White, M | 1 |
| Aban, IB | 1 |
| Aronow, WS | 1 |
| Ahmed, A | 1 |
| Bloomgarden, ZT | 1 |
| Zhao, Z | 1 |
| Abate, N | 1 |
| Chandalia, M | 1 |
| Cabo-Chan, AV | 1 |
| Moe, OW | 1 |
| Sakhaee, K | 1 |
| Barskova, VG | 1 |
| Eliseev, MS | 1 |
| Nasonov, EL | 1 |
| Iakunina, IA | 1 |
| Zilov, AV | 1 |
| Il'inykh, EV | 1 |
| Balasubramanian, T | 1 |
| Kalaitzidis, R | 1 |
| Tsimihodimos, V | 1 |
| Bairaktari, E | 1 |
| Siamopoulos, KC | 1 |
| Elisaf, M | 1 |
| Pylvänen, V | 1 |
| Pakarinen, A | 1 |
| Knip, M | 1 |
| Isojärvi, J | 1 |
| Bonora, E | 3 |
| Capaldo, B | 1 |
| Perin, PC | 1 |
| Del Prato, S | 1 |
| De Mattia, G | 1 |
| Frittitta, L | 1 |
| Frontoni, S | 1 |
| Leonetti, F | 1 |
| Luzi, L | 1 |
| Marchesini, G | 1 |
| Marini, MA | 1 |
| Natali, A | 2 |
| Paolisso, G | 1 |
| Piatti, PM | 1 |
| Pujia, A | 1 |
| Solini, A | 1 |
| Vettor, R | 1 |
| Bonadonna, RC | 1 |
| Rett, K | 1 |
| Wicklmayr, M | 1 |
| Standl, E | 1 |
| Eggenberger, M | 1 |
| Zavaroni, I | 2 |
| Bonini, L | 1 |
| Fantuzzi, M | 2 |
| Dall'Aglio, E | 2 |
| Passeri, M | 2 |
| Reaven, GM | 4 |
| Mazza, S | 1 |
| Delsignore, R | 1 |
| Nishioka, K | 1 |
| Iwatani, M | 1 |
| Muscelli, E | 1 |
| Bianchi, S | 1 |
| Bigazzi, R | 1 |
| Galvan, AQ | 1 |
| Sironi, AM | 1 |
| Frascerra, S | 1 |
| Ciociaro, D | 1 |
| Ferrannini, E | 1 |
| Valensi, P | 1 |
| Paries, J | 1 |
| Maheo, P | 1 |
| Gaudey, F | 1 |
| Attali, JR | 1 |
| Ter Maaten, JC | 2 |
| Voorburg, A | 1 |
| Heine, RJ | 2 |
| Ter Wee, PM | 1 |
| Donker, AJ | 1 |
| Gans, RO | 2 |
| Ariza, CR | 1 |
| Frati, AC | 1 |
| Gómez, G | 1 |
| Almazán, A | 1 |
| Adachi, H | 2 |
| Hashimoto, R | 2 |
| Tsuruta, M | 2 |
| Jacobs, DR | 2 |
| Crow, RS | 1 |
| Imaizumi, T | 2 |
| Luyckx, FH | 1 |
| Scheen, AJ | 1 |
| Desaive, C | 1 |
| Dewe, W | 1 |
| Gielen, JE | 1 |
| Lefebvre, PJ | 1 |
| Emmerson, B | 1 |
| Pogátsa, G | 1 |
| Donskov, AS | 1 |
| Balkarov, IM | 1 |
| Fadina, ZM | 1 |
| Golub', GV | 1 |
| Anikina, SA | 1 |
| Saltykova, NG | 1 |
| Goncharov, VS | 1 |
| Feofanova, ID | 1 |
| Targher, G | 1 |
| Zenere, MB | 1 |
| Saggiani, F | 1 |
| Alberiche, MP | 1 |
| Branzi, P | 1 |
| Muggeo, M | 1 |
| Ovalle, F | 1 |
| Bell, DS | 1 |
| Martínez-Abundis, E | 2 |
| González-Ortiz, M | 2 |
| Grover-Páez, F | 1 |
| Vera-Hernández, A | 1 |
| Mora-Martínez, JM | 1 |
| Bakker, SJ | 1 |
| Teerlink, T | 1 |
| Westerhoff, HV | 1 |
| Chou, P | 1 |
| Lin, KC | 1 |
| Lin, HY | 1 |
| Tsai, ST | 1 |
| Sun, JH | 1 |
| See, LC | 1 |
| Hsu, WC | 1 |
| Tsai, JS | 1 |
| Lin, JD | 1 |
| Imazu, M | 1 |
| Yamamoto, H | 1 |
| Toyofuku, M | 1 |
| Sumii, K | 1 |
| Okubo, M | 1 |
| Egusa, G | 1 |
| Yamakido, M | 1 |
| Kohno, N | 1 |
| Vincent, MA | 1 |
| Dawson, D | 1 |
| Clark, AD | 1 |
| Lindner, JR | 1 |
| Rattigan, S | 1 |
| Clark, MG | 1 |
| Barrett, EJ | 1 |
| Harsch, IA | 1 |
| Schahin, SP | 1 |
| Fuchs, FS | 1 |
| Hahn, EG | 1 |
| Lohmann, T | 1 |
| Konturek, PC | 1 |
| Ficker, JH | 1 |
| Uccella, R | 1 |
| Reiser, S | 1 |
| Powell, AS | 1 |
| Scholfield, DJ | 1 |
| Panda, P | 1 |
| Ellwood, KC | 1 |
| Canary, JJ | 1 |
| Modan, M | 2 |
| Halkin, H | 2 |
| Karasik, A | 1 |
| Lusky, A | 1 |
| Shefi, M | 1 |
| Almog, S | 1 |
| Sonntag, RW | 1 |
| Misbin, RI | 1 |
| Edgar, PJ | 1 |
| Lockwood, DH | 1 |
| Seftel, HC | 1 |
| Spitz, IM | 1 |
| Bersohn, I | 1 |
| Goldin, AR | 1 |
| Joffe, BI | 1 |
| Rubenstein, AH | 1 |
| Metzger, BE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids[NCT00184899] | 20 participants | Interventional | 2005-08-31 | Completed | |||
| Effect of Postprandial Hyperglycemia on Vasculature in Type 1 Diabetes and Healthy Adults[NCT04730882] | 36 participants (Actual) | Observational | 2021-04-06 | Active, not recruiting | |||
| Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults[NCT03520569] | Early Phase 1 | 15 participants (Actual) | Interventional | 2019-02-04 | Completed | ||
| The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in Humans[NCT02490124] | 7 participants (Actual) | Observational | 2014-12-31 | Completed | |||
| The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 Diabetes[NCT03174288] | 32 participants (Actual) | Interventional | 2015-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The augmentation index (AIx) measured at the radial artery is a measure of systemic arterial stiffness, and is defined as the ratio of augmentation (Δ P) to central pulse pressure and expressed as percent. AIx = (ΔP/PP) x 100, where P = pressure and PP = Pulse Pressure. Higher percentages indicate increased arterial stiffness. (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | percentage (Mean) |
|---|---|
| Octreotide- Euglycemia | -4.15 |
| Octreotide - Euglycemia- Insulin Clamp | -2.23 |
| Octreotide- Hyperglycemia | -4.80 |
| Octreotide- Hyperglycemia - Insulin Clamp | -8.45 |
Flow mediated dilation measures the change in brachial diameter in response to 5 minutes of ischemia using B-mode ultrasound. It provides an index of nitric oxide generation by the endothelium . (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | % change (Mean) |
|---|---|
| Octreotide- Euglycemia | 11.8 |
| Octreotide - Euglycemia- Insulin Clamp | 11.8 |
| Octreotide- Hyperglycemia | 8.9 |
| Octreotide- Hyperglycemia - Insulin Clamp | 8.95 |
The time required for a blood pressure wave to travel from the carotid to the femoral artery was measured in meter/sec. This is a measurement of central artery stiffness. Higher numbers indicate stiffer vessels (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | m/sec (Mean) |
|---|---|
| Octreotide- Euglycemia | 5.21 |
| Octreotide - Euglycemia- Insulin Clamp | 5.06 |
| Octreotide- Hyperglycemia | 4.79 |
| Octreotide- Hyperglycemia - Insulin Clamp | 5.07 |
5 reviews available for uric acid and Hyperinsulinism
| Article | Year |
|---|---|
[The metabolic syndrome. Pathophysiologic causes, diagnosis, therapy].
Topics: Arteriosclerosis; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hyperinsulini | 1994 |
[Hypertension, Type II diabetes mellitus and macroangiopathy: risk factors and their association].
Topics: Albuminuria; Alcohol Drinking; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Exercise; Female; H | 1994 |
The kidney: an unwilling accomplice in syndrome X.
Topics: Diabetes Mellitus, Type 2; Glucose; Homeostasis; Humans; Hyperinsulinism; Hypertension; Insulin; Ins | 1997 |
[From type 2 diabetes to metabolic X syndrome].
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hyperinsulinism; Insulin Resistance; Ischemia; Mal | 1999 |
Insulin resistance: a chicken that has come to roost.
Topics: Coronary Disease; Diabetes Mellitus, Type 2; Fibrinolysis; Genotype; Humans; Hyperinsulinism; Hyperl | 1999 |
5 trials available for uric acid and Hyperinsulinism
| Article | Year |
|---|---|
Mycoprotein represents a bioavailable and insulinotropic non-animal-derived dietary protein source: a dose-response study.
Topics: Adult; Amino Acids; Amino Acids, Essential; Appetite; Biological Availability; Body Mass Index; Cros | 2017 |
Effect of insulin on renal sodium and uric acid handling in essential hypertension.
Topics: Adult; Blood Pressure; Female; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Kidney; Ma | 1996 |
Renal handling of urate and sodium during acute physiological hyperinsulinaemia in healthy subjects.
Topics: Adolescent; Adult; Creatine; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin; Kidney; Kidn | 1997 |
Acute effect of physiologic hyperinsulinaemia on serum leptin concentration in healthy young people.
Topics: Acute Disease; Adult; Blood Glucose; Creatinine; Female; Glucose; Hormones; Humans; Hyperinsulinism; | 2000 |
Blood lipids, lipoproteins, apoproteins, and uric acid in men fed diets containing fructose or high-amylose cornstarch.
Topics: Adult; Amylose; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Apolipopr | 1989 |
41 other studies available for uric acid and Hyperinsulinism
| Article | Year |
|---|---|
Bidirectional temporal relationships between uric acid and insulin and their joint impact on incident diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Hyperinsulinism; Insulin; Middle Aged; Risk Factors; Uric | 2023 |
Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis.
Topics: Female; Genome-Wide Association Study; Glucose Transport Proteins, Facilitative; Homeostasis; Humans | 2023 |
Low serum uric acid concentration augments insulin effects on the prevalence of metabolic syndrome.
Topics: Adult; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Hyperinsulinism; Hyperuricemia; I | 2018 |
Oral ethinylestradiol-levonorgestrel normalizes fructose-induced hepatic lipid accumulation and glycogen depletion in female rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Dose-Response Relationship, Drug; Drug C | 2019 |
Retinol-binding protein 4 as a novel risk factor for cardiovascular disease in patients with coronary artery disease and hyperinsulinemia.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies | 2014 |
The Relation between Serum Uric Acid and HbA1c Is Dependent upon Hyperinsulinemia in Patients with Newly Diagnosed Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Creatinine; Databases, Factual; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Te | 2016 |
Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up.
Topics: Biomarkers; Blood Glucose; Cholesterol, HDL; England; Follow-Up Studies; Glucose Intolerance; Humans | 2010 |
Effect of serum insulin on the association between hyperuricemia and incident heart failure.
Topics: Aged; Biomarkers; Female; Heart Failure; Humans; Hyperinsulinism; Hyperuricemia; Incidence; Insulin; | 2010 |
World congress on insulin resistance, diabetes, and cardiovascular disease: Part 1.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, T | 2011 |
[Plasma level of RBP4 in patients with coronary heart disease and the effect of hyperinsulinemia].
Topics: Adult; Aged; Case-Control Studies; Coronary Disease; Female; Humans; Hyperinsulinism; Insulin Resist | 2012 |
The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance.
Topics: Acids; Adult; Female; Humans; Hydrogen-Ion Concentration; Hyperinsulinism; Insulin Resistance; Kidne | 2004 |
[Insulin resistance syndrome in patients with gout and its influence on formation of clinical characteristics of the disease].
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Gout; Humans; | 2004 |
Uric acid or 1-methyl uric acid in the urinary bladder increases serum glucose, insulin, true triglyceride, and total cholesterol levels in Wistar rats.
Topics: Administration, Intravesical; Animals; Blood Glucose; Cholesterol; Female; Hypercholesterolemia; Hyp | 2003 |
Disturbances of phosphate metabolism: another feature of metabolic syndrome.
Topics: Adult; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol, LDL; Creatinine; Electrolytes; F | 2005 |
Insulin-related metabolic changes during treatment with valproate in patients with epilepsy.
Topics: Adult; Anticonvulsants; Body Mass Index; Epilepsy; Female; Humans; Hyperinsulinism; Insulin; Lipopro | 2006 |
Hyperinsulinemia and insulin resistance are independently associated with plasma lipids, uric acid and blood pressure in non-diabetic subjects. The GISIR database.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Cholesterol, HDL; Humans; Hyperinsulinis | 2008 |
Hyperinsulinaemia, obesity, and syndrome X.
Topics: Adult; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Female; Humans; Hyperin | 1994 |
Changes in insulin and lipid metabolism in males with asymptomatic hyperuricaemia.
Topics: Adult; Analysis of Variance; Blood Glucose; Case-Control Studies; Humans; Hyperinsulinism; Hyperlipi | 1993 |
[Hyperuricemia and atherosclerosis].
Topics: Aged; Arteriosclerosis; Diet, Atherogenic; Gout; Humans; Hyperinsulinism; Hyperlipidemias; Hypertens | 1993 |
Erythrocyte rheological changes in obese patients: influence of hyperinsulinism.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Creatinine; Erythrocyte Deformability; Female; Hem | 1996 |
Hyperinsulinemia in patients with coronary heart disease in absence of overt risk factors.
Topics: Adult; Aged; Anthropometry; Blood Glucose; Blood Pressure; C-Peptide; Comorbidity; Convalescence; Co | 1997 |
Hyperinsulinemia and the development of ST-T electrocardiographic abnormalities. An 11-year follow-up study.
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Electrocardiography; Female; | 1997 |
Clustering of cardiovascular risk factors in hyperinsulinemia in Japanese without diabetes.
Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol, LDL; Female; Humans; Hyperinsulinism; Hypertensio | 1998 |
Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity.
Topics: Adult; Belgium; Body Mass Index; Body Weight; Cholesterol; Cholesterol, HDL; Cohort Studies; Comorbi | 1998 |
Hyperlipidaemia in hyperuricaemia and gout.
Topics: Gout; Humans; Hyperinsulinism; Hypertriglyceridemia; Insulin Resistance; Uric Acid | 1998 |
[Urate affection of kidneys and metabolic disturbances in hypertensive patients].
Topics: Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; | 1999 |
Obesity worsens cardiovascular risk profiles independently of hyperinsulinaemia.
Topics: Adult; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Female; Glucose Tolerance Test; Human | 1997 |
Hormone replacement therapy and serum uric acid.
Topics: Cardiovascular Diseases; Estrogen Replacement Therapy; Female; Humans; Hyperinsulinism; Middle Aged; | 1999 |
[Excretion of uric aid, sodium, and potassium in preeclampsia patients and its behavior in acute hyperglycemia-hyperinsulinemia].
Topics: Acute Disease; Adult; Female; Humans; Hyperglycemia; Hyperinsulinism; Potassium; Pre-Eclampsia; Preg | 1999 |
The potential role of adenosine in the pathophysiology of the insulin resistance syndrome.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Coronary Disease; | 2001 |
Gender differences in the relationships of serum uric acid with fasting serum insulin and plasma glucose in patients without diabetes.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus; Fasti | 2001 |
Hyperinsulinemia and insulin resistance related metabolic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Humans; Hyperglycemia; | 2001 |
Hyperinsulinemia for the development of hypertension: data from the Hawaii-Los Angeles-Hiroshima Study.
Topics: Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Female; Hawaii; Humans; Hyperinsulinism | 2001 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Topics: Animals; Biotransformation; Capillaries; Hindlimb; Hyperinsulinism; Infusions, Intravenous; Insulin; | 2002 |
Insulin resistance, hyperleptinemia, and obstructive sleep apnea in Launois-Bensaude syndrome.
Topics: Adult; Aged; Body Mass Index; Glucose Clamp Technique; Humans; Hyperinsulinism; Insulin Resistance; | 2002 |
[The interrelation between obesity, hyperinsulinism and hyperuricemia].
Topics: Adolescent; Adult; Aged; Blood Glucose; Cholesterol; Diabetes Complications; Diabetes Mellitus; Fatt | 1975 |
Elevated serum uric acid--a facet of hyperinsulinaemia.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Hu | 1987 |
Altered erythrocyte and plasma sodium and potassium in hypertension, a facet of hyperinsulinemia.
Topics: Erythrocytes; Female; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Longitudinal Studie | 1988 |
[General medical measures in neoplastic diseases and their complications].
Topics: Anemia; Central Nervous System Diseases; Humans; Hypercalcemia; Hyperinsulinism; Hyperparathyroidism | 1967 |
Adrenergic regulation of insulin secretion during fasting in normal subjects.
Topics: Adrenergic alpha-Antagonists; Adult; Autonomic Nervous System; Blood Glucose; Catecholamines; Fastin | 1970 |
Metabolic features of Johannesburg Bantu with myocardial infarction.
Topics: Adult; Aged; Arteriosclerosis; Black or African American; Black People; Blood Glucose; Fasting; Fema | 1973 |