Page last updated: 2024-10-20

uric acid and Hyperemia

uric acid has been researched along with Hyperemia in 9 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Research Excerpts

ExcerptRelevanceReference
"Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction."9.34Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020)
" Patients (N = 133) with chronic heart failure and comorbid hyperuricemia who enrolled in the Excited-UA study were divided into three tertiles based on their serum uric acid level 24 weeks after initiating xanthine oxidase inhibitor treatment with topiroxostat or allopurinol (i."8.31Optimal uric acid reduction to improve vascular endothelial function in patients with chronic heart failure complicated by hyperuricemia. ( Abe, S; Iida, K; Inoue, K; Inoue, R; Inoue, T; Kato, T; Kitahara, K; Kohno, Y; Koshiji, N; Naganuma, J; Sakuma, M; Toyoda, S; Yamauchi, F; Yokomachi, J, 2023)
"Serum uric acid (SUA) level is known to have a prognostic value in patients with acute coronary syndrome (ACS)."7.91Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome. ( Fujimoto, Y; Kitahara, H; Kobayashi, Y; Nakayama, T; Saito, Y, 2019)
" In this study, we investigated the influence of early postischemic hyperemia on brain damage and middle cerebral artery (MCA) properties and the effect of treatment with the endogenous antioxidant uric acid (UA)."7.81Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: a target of uric acid treatment. ( Chamorro, A; Cugota, R; Dantas, AP; Jiménez-Altayó, F; Onetti, Y; Pérez, B; Planas, AM; Vila, E, 2015)
"Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction."5.34Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020)
" Patients (N = 133) with chronic heart failure and comorbid hyperuricemia who enrolled in the Excited-UA study were divided into three tertiles based on their serum uric acid level 24 weeks after initiating xanthine oxidase inhibitor treatment with topiroxostat or allopurinol (i."4.31Optimal uric acid reduction to improve vascular endothelial function in patients with chronic heart failure complicated by hyperuricemia. ( Abe, S; Iida, K; Inoue, K; Inoue, R; Inoue, T; Kato, T; Kitahara, K; Kohno, Y; Koshiji, N; Naganuma, J; Sakuma, M; Toyoda, S; Yamauchi, F; Yokomachi, J, 2023)
"Serum uric acid (SUA) level is known to have a prognostic value in patients with acute coronary syndrome (ACS)."3.91Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome. ( Fujimoto, Y; Kitahara, H; Kobayashi, Y; Nakayama, T; Saito, Y, 2019)
" In this study, we investigated the influence of early postischemic hyperemia on brain damage and middle cerebral artery (MCA) properties and the effect of treatment with the endogenous antioxidant uric acid (UA)."3.81Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: a target of uric acid treatment. ( Chamorro, A; Cugota, R; Dantas, AP; Jiménez-Altayó, F; Onetti, Y; Pérez, B; Planas, AM; Vila, E, 2015)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Naganuma, J1
Sakuma, M1
Kitahara, K1
Kato, T1
Yokomachi, J1
Yamauchi, F1
Inoue, R1
Iida, K1
Kohno, Y1
Inoue, K1
Koshiji, N1
Abe, S1
Toyoda, S1
Inoue, T1
Taher, R1
Sara, JD1
Prasad, M1
Kolluri, N1
Toya, T1
Lerman, LO1
Lerman, A1
Saito, Y2
Kitahara, H2
Nishi, T1
Fujimoto, Y2
Kobayashi, Y2
Nakata, T1
Ikeda, S1
Koga, S1
Yonekura, T1
Tsuneto, A1
Doi, Y1
Fukae, S1
Minami, T1
Kawano, H1
Maemura, K1
Nakayama, T1
Ferreira, TDS1
Fernandes, JFR1
Araújo, LDS1
Nogueira, LP1
Leal, PM1
Antunes, VP1
Rodrigues, MLG1
Valença, DCT1
Kaiser, SE1
Klein, MRST1
Onetti, Y1
Dantas, AP1
Pérez, B1
Cugota, R1
Chamorro, A1
Planas, AM1
Vila, E1
Jiménez-Altayó, F1
Wijnands, JM1
Houben, AJ1
Muris, DM1
Boonen, A1
Schram, MT1
Sep, SJ1
van der Kallen, CJ1
Henry, RM1
Dagnelie, PC1
van der Linden, S1
Schaper, NC1
Arts, IC1
Stehouwer, CD1
Gonçalves, MC1
Bezerra, FF1
Eleutherio, EC1
Bouskela, E1
Koury, J1

Trials

1 trial available for uric acid and Hyperemia

ArticleYear
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia.
    International heart journal, 2020, Sep-29, Volume: 61, Issue:5

    Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; F

2020

Other Studies

8 other studies available for uric acid and Hyperemia

ArticleYear
Optimal uric acid reduction to improve vascular endothelial function in patients with chronic heart failure complicated by hyperuricemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:3

    Topics: Chronic Disease; Diuretics; Endothelium, Vascular; Enzyme Inhibitors; Heart Failure; Humans; Hyperem

2023
Elevated serum uric acid is associated with peripheral endothelial dysfunction in women.
    Atherosclerosis, 2019, Volume: 290

    Topics: Adult; Biomarkers; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Hyperemia; Hyperu

2019
Systemic endothelial dysfunction in patients with vasospastic and microvascular angina: serum uric acid as a marker of reactive hyperemia index.
    Coronary artery disease, 2020, Volume: 31, Issue:6

    Topics: Aged; Biomarkers; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular;

2020
Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome.
    Journal of atherosclerosis and thrombosis, 2019, Apr-01, Volume: 26, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Biomarkers; Endothelium, Vascular; Female; Follow-Up Studies; Humans;

2019
Serum Uric Acid Levels are Associated with Cardiometabolic Risk Factors in Healthy Young and Middle-Aged Adults.
    Arquivos brasileiros de cardiologia, 2018, Volume: 111, Issue:6

    Topics: Adiposity; Adult; Blood Pressure; C-Reactive Protein; Cholesterol; Cross-Sectional Studies; Diet Sur

2018
Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: a target of uric acid treatment.
    American journal of physiology. Heart and circulatory physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Animals; Antioxidants; Hyperemia; Infarction, Middle Cerebral Artery; Interleukin-18; Male; Oxidativ

2015
Uric acid and skin microvascular function: the Maastricht study.
    Journal of hypertension, 2015, Volume: 33, Issue:8

    Topics: Adult; Aged; Capillaries; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypere

2015
Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:9

    Topics: Adult; Athletes; Beverages; Blood Glucose; Erythrocytes; Food, Organic; Homeostasis; Humans; Hyperem

2011