uric acid has been researched along with Hemorrhagic Shock in 27 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid is persistently high after HS and leads to the activation of caspases-8 and organ inflammation; these can be prevented by an intervention to degrade UA." | 7.91 | Caspase-(8/3) activation and organ inflammation in a rat model of resuscitated hemorrhagic shock: A role for uric acid. ( Baril, F; Bouchard, C; Brochiero, E; Cardinal, AM; Charbonney, E; Dunberry-Poissant, S; Gilbert, K; Khazoom, F; Rousseau, G; Vega, MA, 2019) |
| "Secondary brain injury following hemorrhagic shock (HS) is a frequent complication in patients, even in the absence of direct brain trauma, leading to behavioral changes and more specifically anxiety and depression." | 5.62 | Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock. ( Bernard, F; Beyrouthy, J; Bouchard, C; Brochu, B; Charbonney, E; Gagné, MA; Gilbert, K; Khazoom, F; L'Ecuyer, S; Liu, C; Rousseau, G, 2021) |
| "The results showed hemorrhagic shock caused a significant rise in plasma NE, E, AD, and uric acid levels, but the magnitudes and time profiles were different among them." | 5.27 | Adenosine in hemorrhagic shock: possible role in attenuating sympathetic activation. ( Chu, KM; Tseng, CJ; Tung, CS; Yin, TH, 1987) |
| "Uric acid is persistently high after HS and leads to the activation of caspases-8 and organ inflammation; these can be prevented by an intervention to degrade UA." | 3.91 | Caspase-(8/3) activation and organ inflammation in a rat model of resuscitated hemorrhagic shock: A role for uric acid. ( Baril, F; Bouchard, C; Brochiero, E; Cardinal, AM; Charbonney, E; Dunberry-Poissant, S; Gilbert, K; Khazoom, F; Rousseau, G; Vega, MA, 2019) |
| "Biochemical effects of treatment with a xanthine oxidase inhibitor (allopurinol) were investigated in an experimental hemorrhagic shock procedure." | 3.66 | Effect of a xanthine oxidase inhibitor on adenine nucleotide degradation in hemorrhagic shock. ( Cunningham, SK; Keaveny, TV, 1978) |
| "Secondary brain injury following hemorrhagic shock (HS) is a frequent complication in patients, even in the absence of direct brain trauma, leading to behavioral changes and more specifically anxiety and depression." | 1.62 | Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock. ( Bernard, F; Beyrouthy, J; Bouchard, C; Brochu, B; Charbonney, E; Gagné, MA; Gilbert, K; Khazoom, F; L'Ecuyer, S; Liu, C; Rousseau, G, 2021) |
| "In a hemorrhagic shock model without adequate volume resuscitation we investigated the question whether a biochemical stabilization of liver function by applying 2-mercaptopropionyl-glycine (2MPG) may influence the shock dynamics especially the transition from compensated to decompensated shock and the development of multiple organ failure (MOF)." | 1.29 | Involvement of liver in the decompensation of hemorrhagic shock. ( Henrich, HA; Kobelt, F; Schreck, U, 1994) |
| "The results showed hemorrhagic shock caused a significant rise in plasma NE, E, AD, and uric acid levels, but the magnitudes and time profiles were different among them." | 1.27 | Adenosine in hemorrhagic shock: possible role in attenuating sympathetic activation. ( Chu, KM; Tseng, CJ; Tung, CS; Yin, TH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (81.48) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Khazoom, F | 3 |
| L'Écuyer, S | 2 |
| Gilbert, K | 3 |
| Gagné, MA | 2 |
| Bouchard, C | 3 |
| Rose, CF | 1 |
| Rousseau, G | 3 |
| Charbonney, E | 3 |
| Brochu, B | 1 |
| Beyrouthy, J | 1 |
| Liu, C | 1 |
| Bernard, F | 1 |
| Dunberry-Poissant, S | 1 |
| Baril, F | 1 |
| Cardinal, AM | 1 |
| Vega, MA | 1 |
| Brochiero, E | 1 |
| Cowsert, MK | 2 |
| Carrier, O | 2 |
| Adachi, H | 2 |
| Furukawa, T | 1 |
| Motomatsu, K | 1 |
| Abraham, J | 3 |
| Hopkins, RW | 3 |
| Damewood, CA | 3 |
| Simeone, FA | 3 |
| Kobelt, F | 1 |
| Schreck, U | 1 |
| Henrich, HA | 1 |
| Tsukada, K | 1 |
| Hasegawa, T | 1 |
| Tsutsumi, S | 1 |
| Katoh, H | 1 |
| Kuwano, H | 1 |
| Miyazaki, T | 1 |
| Yamamoto, Y | 1 |
| Cunningham, SK | 1 |
| Keaveny, TV | 1 |
| Saugstad, OD | 1 |
| Ostrem, T | 1 |
| Tung, CS | 1 |
| Chu, KM | 1 |
| Tseng, CJ | 1 |
| Yin, TH | 1 |
| Owens, ML | 1 |
| Lazarus, HM | 1 |
| Wolcott, MW | 1 |
| Maxwell, JG | 1 |
| Taylor, JB | 1 |
| Fox, IH | 1 |
| Kuska, J | 1 |
| Hollmén, A | 1 |
| Pihlajaniemi, R | 1 |
| Reinilä, M | 1 |
| Ryhänen, P | 1 |
| Chien, S | 1 |
| Dellenback, RJ | 1 |
| Usami, S | 1 |
| Burton, DA | 1 |
| Gustavson, PF | 1 |
| Magazinovic, V | 1 |
| Fronek, A | 1 |
| Rosen, H | 1 |
| Witzel, T | 1 |
| Zweifach, BW | 1 |
| Salles, MS | 1 |
| Tabatabai, M | 1 |
| Shahidi, HA | 1 |
| Mertz, DP | 1 |
| Jones, CE | 2 |
| Crowell, JW | 3 |
| Smith, EE | 2 |
| Lefer, AM | 2 |
| Daw, JC | 1 |
| Berne, RM | 1 |
| Brand, E | 1 |
| Cowgill, R | 1 |
2 reviews available for uric acid and Hemorrhagic Shock
| Article | Year |
|---|---|
Purine ribonucleotide catabolism: clinical and biochemical significance. Review.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Carbohydrate Metabolism, Inborn Errors; Fructose; Huma | 1974 |
[Effect of purine metabolism on renal function].
Topics: Alcoholic Intoxication; Female; Humans; Kidney; Lesch-Nyhan Syndrome; Male; Physical Exertion; Pre-E | 1974 |
25 other studies available for uric acid and Hemorrhagic Shock
| Article | Year |
|---|---|
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
Topics: Animals; Biomarkers; Disease Models, Animal; Intestinal Mucosa; Liver; Lung Injury; Male; Permeabili | 2020 |
Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock.
Topics: Animals; Anxiety; Brain Injuries; Disease Models, Animal; Inflammation Mediators; Male; Random Alloc | 2021 |
Caspase-(8/3) activation and organ inflammation in a rat model of resuscitated hemorrhagic shock: A role for uric acid.
Topics: Animals; Apoptosis; Biomarkers; Caspases; Disease Models, Animal; Inflammation; Male; Rats; Rats, Wi | 2019 |
The effect of some autonomic drugs on the uric acidemia of hemorrhagic shock.
Topics: Animals; Blood Pressure; Dogs; Female; Hypoxia; Isoproterenol; Male; Norepinephrine; Phenoxybenzamin | 1967 |
[The effect of vitamin E on the serum lipid-peroxide and uric acid in the hemorrhagic shock rabbit (author's transl)].
Topics: Animals; Lipid Peroxides; Male; Rabbits; Shock, Hemorrhagic; Uric Acid; Vitamin E | 1982 |
Effects of 2-ethylamino-1,3,4-thiadiazole on hepatic adenosine nucleotides in experimental hemorrhagic shock.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Allantoin; Animals; Antineoplastic Agents; Blood Pressu | 1980 |
Involvement of liver in the decompensation of hemorrhagic shock.
Topics: Acetoacetates; Ammonia; Animals; Blood Glucose; Blood Pressure; Cats; Diastole; Female; Hydroxybutyr | 1994 |
Effect of uric acid on liver injury during hemorrhagic shock.
Topics: Animals; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Liver; Lysine; Male; Nitric Oxi | 2000 |
Effect of a xanthine oxidase inhibitor on adenine nucleotide degradation in hemorrhagic shock.
Topics: Acid Phosphatase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Tri | 1978 |
Hypoxanthine and urate levels of plasma during and after hemorrhagic hypotension in dogs.
Topics: Animals; Dogs; Hypoxanthines; Lung; Shock, Hemorrhagic; Uric Acid | 1977 |
[The preventive effect of allopurinol on experimental shock (author's transl)].
Topics: Adenine Nucleotides; Allopurinol; Animals; Male; Rabbits; Rats; Shock; Shock, Hemorrhagic; Uric Acid | 1977 |
Levels of allantoin and uric acid in dogs subjected to hemorrhagic shock.
Topics: Adenine Nucleotides; Allantoin; Animals; Dogs; Guanine Nucleotides; Liver; Lymph; Shock, Hemorrhagic | 1975 |
Effects of allopurinol on hepatic adenosine nucleotides in hemorrhagic shock.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Allantoin; Allopurinol; Anim | 1975 |
Adenosine in hemorrhagic shock: possible role in attenuating sympathetic activation.
Topics: Adenosine; Animals; Blood Pressure; Epinephrine; Heart Rate; Male; Norepinephrine; Rabbits; Shock, H | 1987 |
Allopurinol and hypoxanthine pretreatment of canine kidney donors.
Topics: Allopurinol; Animals; Creatinine; Dogs; Drug Therapy, Combination; Graft Rejection; Hypoxanthines; I | 1974 |
The metabolic response of the liver when acute experimental haemorrhagic shock is treated with dextran or gelatin-type plasma expanders.
Topics: Animals; Blood Pressure; Blood Volume; Carbon Dioxide; Dextrans; Dogs; Galactose; Gelatin; Half-Life | 1972 |
Blood volume, hemodynamic, and metabolic changes in hemorrhagic shock in normal and splenectomized dogs.
Topics: Acid-Base Equilibrium; Animals; Blood Glucose; Blood Pressure; Blood Proteins; Blood Viscosity; Bloo | 1973 |
Ornithine carbamoyl transferase as an index of severity in hemorrhagic shock.
Topics: Animals; Blood Pressure; Blood Proteins; Dogs; Hematocrit; Lactates; Ornithine Carbamoyltransferase; | 1974 |
Blood glucose levels in dogs pretreated with allopurinol during hemorrhagic shock.
Topics: Allopurinol; Animals; Blood Glucose; Blood Pressure; Depression, Chemical; Dogs; Female; Male; Shock | 1972 |
[Acute kidney failure and hyperuricemia].
Topics: Acidosis, Respiratory; Acute Kidney Injury; Allopurinol; Animals; Anuria; Dogs; Gout; Humans; Hypoxa | 1971 |
Significance of increased blood uric acid following extensive hemorrhage.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Chromatography, Paper; Dogs; Hypotension; Oxygen; O | 1968 |
Cardiac and skeletal muscle metabolic energy stores in hemorrhagic shock.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Arteries; Blood Pressure; Cats; Dogs; Glycogen; Heart | 1969 |
Further characterization of a myocardial depressant factor present in hemorrhagic shock.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adrenochrome; Animals; Anti-Arrhythmia Agents; Catechol | 1969 |
Effect of allopurinol on hemorrhagic shock.
Topics: Allopurinol; Animals; Blood Pressure; Dogs; Hypoxanthines; Methods; Oxygen Consumption; Purines; Sho | 1969 |
The effect of hemorrhagic shock on blood uric acid level.
Topics: Animals; Blood Pressure; Dogs; Nucleosides; Shock, Hemorrhagic; Uric Acid | 1966 |