Page last updated: 2024-10-20

uric acid and Glucosephosphate Dehydrogenase Deficiency

uric acid has been researched along with Glucosephosphate Dehydrogenase Deficiency in 13 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Glucosephosphate Dehydrogenase Deficiency: A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.

Research Excerpts

ExcerptRelevanceReference
"Bilirubin and Hb were unchanged."2.78Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency. ( Deli, CK; Fatouros, IG; Georgakouli, K; Jamurtas, AZ; Kouretas, D; Koutedakis, Y; Zalavras, A, 2013)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Ganapathi, M1
Campbell, P1
Ofori, K1
Aggarwal, V1
Francis, RO1
Kratz, A1
Jung, S1
Sayad, K1
Staitieh, BS1
Georgakouli, K1
Deli, CK1
Zalavras, A1
Fatouros, IG1
Kouretas, D1
Koutedakis, Y1
Jamurtas, AZ1
BROMBACHER, PJ1
VANCREVELD, S1
DAMME, JP1
HUIJING, F1
PLOEM, JE1
Jakovcic, S1
Sorensen, LB1
Greene, HL1
al-Ali, AK1
Ahmed, MA1
Qaw, FS1
al-Fadel Saleh, M1
al-Bashir, A1
Corbucci, GG1
Dancis, J1
Yip, LC1
Cox, RP1
Piomelli, S1
Balis, ME1
Buchanan, KD1
Watts, RW1
Kelley, WN1
Rosenbloom, FM1
Seegmiller, JE1
Howell, RR1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Alpha Lipoic Acid Supplementation in G6PD Deficient Individuals After Acute Exercise[NCT02937363]10 participants (Actual)Interventional2016-12-31Completed
The Association Between Oxidative Stress and Carbohydrate Metabolism Disorders in G6PD Deficient Individuals[NCT05571748]40 participants (Anticipated)Interventional2023-02-28Not yet recruiting
Effects of N-acetyl Cystein (NAC) Supplementation in G6PD Deficient Individuals After Acute Exercise[NCT02937376]Early Phase 112 participants (Anticipated)Interventional2023-02-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for uric acid and Glucosephosphate Dehydrogenase Deficiency

ArticleYear
Glycogen storage disease.
    Seminars in liver disease, 1982, Volume: 2, Issue:4

    Topics: Blood Glucose; Glucosephosphate Dehydrogenase Deficiency; Glycogen; Glycogen Storage Disease; Glycog

1982
Diabetes mellitus and gout.
    Seminars in arthritis and rheumatism, 1972,Fall, Volume: 2, Issue:2

    Topics: Benzothiadiazines; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus

1972
Molecular variation in relation to purine metabolism.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1974, Volume: 8

    Topics: Amidophosphoribosyltransferase; Chemical Phenomena; Chemistry; Glucosephosphate Dehydrogenase Defici

1974

Trials

2 trials available for uric acid and Glucosephosphate Dehydrogenase Deficiency

ArticleYear
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 61

    Topics: Adult; Antioxidants; Bilirubin; Catalase; Dietary Supplements; Glucosephosphate Dehydrogenase Defici

2013
The role of reduced glutathione during the course of acute haemolysis in glucose-6-phosphate dehydrogenase deficient patients: clinical and pharmacodynamic aspects.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Cell Hypoxia; Double-Blind Met

1990

Other Studies

8 other studies available for uric acid and Glucosephosphate Dehydrogenase Deficiency

ArticleYear
Impact of pre-emptive rapid testing for glucose-6-phosphate dehydrogenase deficiency prior to rasburicase administration at a tertiary care centre: A retrospective study.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:9

    Topics: Female; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans; Retrospective Studies; Tertiar

2022
Low Hemoglobin Saturation in the Setting of Hyperuricemia.
    Annals of the American Thoracic Society, 2019, Volume: 16, Issue:11

    Topics: Aged; Female; Glucosephosphate Dehydrogenase Deficiency; Gout Suppressants; Hemoglobins; Humans; Hyp

2019
A REPORT OF TWO ADULT PATIENTS WITH GLYCOGEN STORAGE DISEASE.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Acetone; Adult; Blood Glucose; Carbohydrate Metabolism; Child; Epinephrine; Galactose; Glucagon; Glu

1964
Studies of uric acid metabolism in glycogen storage disease associated with gouty arthritis.
    Arthritis and rheumatism, 1967, Volume: 10, Issue:2

    Topics: Adolescent; Allopurinol; Body Height; Body Weight; Carbon Isotopes; Enzyme Therapy; Glucosephosphate

1967
Uric acid, creatinine and urea in normal, glucose-6-phosphate dehydrogenase-deficient and Hb SS Saudi subjects.
    Acta haematologica, 1995, Volume: 94, Issue:2

    Topics: Anemia, Sickle Cell; Creatinine; Glucosephosphate Dehydrogenase Deficiency; Humans; Saudi Arabia; Si

1995
Vitamin C toxicity.
    Nutrition reviews, 1976, Volume: 34, Issue:8

    Topics: Ascorbic Acid; Burns; Dose-Response Relationship, Drug; Erythrocytes; Female; Glucosephosphate Dehyd

1976
Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:8

    Topics: Adolescent; Carbon Isotopes; Diphosphates; Epilepsy, Tonic-Clonic; Erythrocytes; Genotype; Glucoseph

1973
Excessive production of uric acid in type I glycogen storage disease.
    The Journal of pediatrics, 1968, Volume: 72, Issue:4

    Topics: Adolescent; Carbon Isotopes; Female; Glucosephosphate Dehydrogenase Deficiency; Glucosyltransferases

1968