uric acid has been researched along with Gait Disorders, Animal in 13 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the ability of a proprietary antagonist of E-type prostanoid receptor (EP) 4, grapiprant, and carprofen to attenuate lameness attributable to urate-induced synovitis in dogs." | 9.30 | Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Sandberg, GS, 2019) |
| "A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis." | 9.13 | Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs. ( Hanson, PD; Hazewinkel, HA; Pollmeier, M; Theyse, LF; van den Brom, WE, 2008) |
| "This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness." | 9.12 | Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs. ( Drag, M; Hanson, PD; Kunkle, BN; Romano, D, 2007) |
| "Carprofen was also somewhat effective in attenuating the severity of urate-induced synovitis but to a lesser degree than the medium dose of deracoxib." | 6.70 | Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs. ( Buonomo, FC; Millis, DL; Moyers, T; Weigel, JP, 2002) |
| "To investigate the ability of a proprietary antagonist of E-type prostanoid receptor (EP) 4, grapiprant, and carprofen to attenuate lameness attributable to urate-induced synovitis in dogs." | 5.30 | Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Sandberg, GS, 2019) |
| "A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis." | 5.13 | Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs. ( Hanson, PD; Hazewinkel, HA; Pollmeier, M; Theyse, LF; van den Brom, WE, 2008) |
| "This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness." | 5.12 | Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs. ( Drag, M; Hanson, PD; Kunkle, BN; Romano, D, 2007) |
| "The optimum doses of carprofen, flunixin, ketoprofen and sodium salicylate for the treatment of inflammatory pain were determined in domestic fowl using the microcrystalline sodium urate model of articular pain." | 5.11 | Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl. ( Gentle, MJ; Hocking, PM; Robertson, GW, 2005) |
| "Firocoxib treatment prior to induction of arthritis in dogs resulted in a high level of analgesia from the first post-treatment assessment at 1." | 2.90 | Assessment of the efficacy of firocoxib (Previcox®) and grapiprant (Galliprant®) in an induced model of acute arthritis in dogs. ( Beugnet, F; de Salazar Alcalá, AG; Dehman, A; Gioda, L, 2019) |
| "For firocoxib, there was no difference from baseline scores in lameness scores at any point." | 2.77 | Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis. ( Al-Nadaf, S; Budsberg, SC; Cathcart, CJ; Johnston, SA; Reynolds, LR, 2012) |
| "On the fourth day after initiation of treatment, synovitis was induced via intra-articular injection of SU 1 hour before administration of the last treatment dose." | 2.76 | Effect of perzinfotel and a proprietary phospholipase A(2) inhibitor on kinetic gait and subjective lameness scores in dogs with sodium urate-induced synovitis. ( Al-Nadaf, S; Budsberg, SC; Cathcart, CJ; Clark, JD; Eppler, CM; Reynolds, LR; Torres, BT; Zwijnenberg, RJ, 2011) |
| "Carprofen was also somewhat effective in attenuating the severity of urate-induced synovitis but to a lesser degree than the medium dose of deracoxib." | 2.70 | Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs. ( Buonomo, FC; Millis, DL; Moyers, T; Weigel, JP, 2002) |
| "A blinded, randomized, controlled single crossover design study was performed to determine the efficacy of meloxicam, using 2 dosage groups." | 2.68 | Kinetic gait analysis assessment of meloxicam efficacy in a sodium urate-induced synovitis model in dogs. ( Budsberg, SC; Cross, AR; Keefe, TJ, 1997) |
| "Synovitis was then induced in the left stifle joint by intra-articular injection of monosodium urate." | 1.34 | Kinetic gait and subjective analysis of the effects of a tachykinin receptor antagonist in dogs with sodium urate-induced synovitis. ( Budsberg, SC; Claxton, RF; Punke, JP; Reynolds, LR; Speas, AL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Salazar Alcalá, AG | 1 |
| Gioda, L | 1 |
| Dehman, A | 1 |
| Beugnet, F | 1 |
| Budsberg, SC | 5 |
| Kleine, SA | 1 |
| Norton, MM | 1 |
| Sandberg, GS | 1 |
| Hassan, EA | 1 |
| Lambrechts, NE | 1 |
| Moore, GE | 1 |
| Weng, HY | 1 |
| Heng, HG | 1 |
| Breur, GJ | 1 |
| Borer, LR | 1 |
| Seewald, W | 1 |
| Peel, JE | 1 |
| King, JN | 1 |
| Carroll, GL | 1 |
| Narbe, R | 1 |
| Peterson, K | 1 |
| Kerwin, SC | 1 |
| Taylor, L | 1 |
| DeBoer, M | 1 |
| Torres, BT | 1 |
| Zwijnenberg, RJ | 1 |
| Eppler, CM | 1 |
| Clark, JD | 1 |
| Cathcart, CJ | 2 |
| Reynolds, LR | 3 |
| Al-Nadaf, S | 2 |
| Johnston, SA | 1 |
| Millis, DL | 1 |
| Weigel, JP | 1 |
| Moyers, T | 1 |
| Buonomo, FC | 1 |
| Hocking, PM | 1 |
| Robertson, GW | 1 |
| Gentle, MJ | 1 |
| Hazewinkel, HA | 1 |
| van den Brom, WE | 1 |
| Theyse, LF | 1 |
| Pollmeier, M | 1 |
| Hanson, PD | 2 |
| Drag, M | 1 |
| Kunkle, BN | 1 |
| Romano, D | 1 |
| Punke, JP | 1 |
| Speas, AL | 1 |
| Claxton, RF | 1 |
| Cross, AR | 1 |
| Keefe, TJ | 1 |
10 trials available for uric acid and Gait Disorders, Animal
| Article | Year |
|---|---|
Assessment of the efficacy of firocoxib (Previcox®) and grapiprant (Galliprant®) in an induced model of acute arthritis in dogs.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dog Dise | 2019 |
Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cross-Over Studies; Dog Diseases; Dogs | 2019 |
Evaluation of the dose-response relationship of oral robenacoxib in urate crystal-induced acute stifle synovitis in dogs.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxyge | 2017 |
Effect of perzinfotel and a proprietary phospholipase A(2) inhibitor on kinetic gait and subjective lameness scores in dogs with sodium urate-induced synovitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azabicyclo Compounds; Blood Proteins; Carbazoles; | 2011 |
Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis.
Topics: 4-Butyrolactone; Analgesia; Animals; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Dog Diseases; | 2012 |
Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cyclooxygenase I | 2002 |
Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chickens; Clonixin; Dose-Response Rela | 2005 |
Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carbazoles; Cross-Over | 2008 |
Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs.
Topics: 4-Butyrolactone; Animals; Carbazoles; Cyclooxygenase 2 Inhibitors; Dog Diseases; Dogs; Female; Lamen | 2007 |
Kinetic gait analysis assessment of meloxicam efficacy in a sodium urate-induced synovitis model in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase Inhibitors; Dog | 1997 |
3 other studies available for uric acid and Gait Disorders, Animal
| Article | Year |
|---|---|
Development of a model to induce transient synovitis and lameness in the hip joint of dogs.
Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Dog Diseases; Dogs; Female; Gait; Injectio | 2015 |
A pilot study: sodium urate synovitis as an acute model of inflammatory response using objective and subjective criteria to evaluate arthritic pain in cats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Area Under Curve; Cats; Female; Infl | 2008 |
Kinetic gait and subjective analysis of the effects of a tachykinin receptor antagonist in dogs with sodium urate-induced synovitis.
Topics: Administration, Oral; Animals; Cross-Over Studies; Dog Diseases; Dogs; Female; Gait; Lameness, Anima | 2007 |