Page last updated: 2024-10-20

uric acid and Endotoxemia

uric acid has been researched along with Endotoxemia in 6 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
" No significant changes were observed in fasting plasma glucose, quantitative insulin sensitivity check index, hs-CRP, superoxide dismutase, catalase and uric acid in the RS2 group as compared with the control group."5.22The Therapeutic Potential of Resistant Starch in Modulation of Insulin Resistance, Endotoxemia, Oxidative Stress and Antioxidant Biomarkers in Women with Type 2 Diabetes: A Randomized Controlled Clinical Trial. ( Dehghan, P; Farhangi, MA; Gargari, BP; Karimi, P; Pouraghaei, M; Sarmadi, B; Zare Javid, A, 2016)
"This study in dogs was performed to assess circulating choline status during endotoxemia and to determine whether choline administration can protect dogs from endotoxin-induced tissue injuries."3.73Endotoxin alters serum-free choline and phospholipid-bound choline concentrations, and choline administration attenuates endotoxin-induced organ injury in dogs. ( Ilcol, YO; Ulus, IH; Yilmaz, Z, 2005)
"Sesame oil ameliorated multiple organ failure and mortality via its inhibition of xanthine oxidase in lipopolysaccharide-dosed rats."1.31Sesame oil attenuates multiple organ failure and increases survival rate during endotoxemia in rats. ( Hsu, DZ; Liu, MY, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lenglet, A1
Fabresse, N1
Taupin, M1
Gomila, C1
Liabeuf, S1
Kamel, S1
Alvarez, JC1
Drueke, TB1
Massy, ZA1
Karimi, P1
Farhangi, MA1
Sarmadi, B1
Gargari, BP1
Zare Javid, A1
Pouraghaei, M1
Dehghan, P1
Hsu, DZ1
Liu, MY1
Ilcol, YO1
Yilmaz, Z1
Ulus, IH1
Heller, AR1
Rothermel, J1
Weigand, MA2
Plaschke, K1
Schmeck, J1
Wendel, M1
Bardenheuer, HJ2
Koch, T1
Schmidt, H1
Li, C1
Schmidt, W1
Martin, E1

Trials

2 trials available for uric acid and Endotoxemia

ArticleYear
Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?
    Drugs, 2019, Volume: 79, Issue:8

    Topics: Aged; Endotoxemia; Endotoxins; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Human

2019
The Therapeutic Potential of Resistant Starch in Modulation of Insulin Resistance, Endotoxemia, Oxidative Stress and Antioxidant Biomarkers in Women with Type 2 Diabetes: A Randomized Controlled Clinical Trial.
    Annals of nutrition & metabolism, 2016, Volume: 68, Issue:2

    Topics: Adult; Aged; Antioxidants; Biomarkers; Blood Glucose; Body Weight; C-Reactive Protein; Diabetes Mell

2016

Other Studies

4 other studies available for uric acid and Endotoxemia

ArticleYear
Sesame oil attenuates multiple organ failure and increases survival rate during endotoxemia in rats.
    Critical care medicine, 2002, Volume: 30, Issue:8

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxemia; Kidney; Lipid Peroxi

2002
Endotoxin alters serum-free choline and phospholipid-bound choline concentrations, and choline administration attenuates endotoxin-induced organ injury in dogs.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Choline; Creatine

2005
Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine Diphosphate; Ad

2007
Intestinal formation of hypoxanthine and uric acid during endotoxemia.
    The Journal of surgical research, 1997, Jul-15, Volume: 71, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Endotoxemia; Hematocrit; Hypoxanthine; Intestinal Mucosa; Leukoc

1997