Page last updated: 2024-10-20

uric acid and Emesis

uric acid has been researched along with Emesis in 27 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis."9.08Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997)
"Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances."7.96Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020)
"We report five cases of vomiting associated with a very important increase of maternal plasma uric acid (> 595 mmol/l, 100 mg/l) at the third trimester of pregnancy."7.72[Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome]. ( Bresson-Just, S; Codaccioni, X; Herchin-Decobert, A; Houfflin-Debarge, V; Moranne, O; Subtil, D, 2004)
"Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks."7.67Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985)
"A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis."5.08Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997)
"Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances."3.96Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020)
"We report five cases of vomiting associated with a very important increase of maternal plasma uric acid (> 595 mmol/l, 100 mg/l) at the third trimester of pregnancy."3.72[Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome]. ( Bresson-Just, S; Codaccioni, X; Herchin-Decobert, A; Houfflin-Debarge, V; Moranne, O; Subtil, D, 2004)
"The presence of nausea and vomiting, epigastric pain, or both in association with admission laboratory values that are in excess of the cutoffs for lactate dehydrogenase, aspartate aminotransferase, and uric acid concentrations or for all 6 tests is predictive of high risk of morbidity for the patient with severe preeclampsia."3.70Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999)
"Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks."3.67Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985)
"Long-term flexible dosing with colestilan reduces serum phosphorus and demonstrates an acceptable safety and tolerability profile."2.82Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia. ( Dimkovic, N; Locatelli, F; Spasovski, G; Wanner, C, 2016)
"Hematuria was found in 85% of dogs in which urinalysis was performed."1.30Surgical treatment of urate calculi in Dalmatians: 38 cases (1980-1995). ( Birchard, SJ; Chew, DJ; Collins, RL; Heuter, KJ, 1998)
"Class 3 HELLP syndrome is considered a clinically significant transitional group."1.30The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's6 (22.22)18.2507
2000's2 (7.41)29.6817
2010's1 (3.70)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Lee, J1
Jung, SM1
Jeon, S1
Locatelli, F1
Spasovski, G1
Dimkovic, N1
Wanner, C1
LAMAR, CP1
Bresson-Just, S1
Houfflin-Debarge, V1
Herchin-Decobert, A1
Moranne, O1
Codaccioni, X1
Subtil, D1
Deal, C1
Omizo, M1
Schwartz, EN1
Eriksen, EF1
Cantor, P1
Wang, J1
Glass, EV1
Myers, SL1
Krege, JH1
Emmerson, BT1
Neyer, U1
Wöss, E1
Haller, R1
Kröss, R1
Jacobs, F1
Hurault de Ligny, B1
Le Goff, C1
Ryckelynck, JP1
Banks, PA1
Hughes, M1
Ferrante, M1
Noordhoek, EC1
Ramagopal, V1
Slivka, A1
Gröbner, W1
Walter-Sack, I1
de Vries, JX1
Collins, RL1
Birchard, SJ1
Chew, DJ1
Heuter, KJ1
Martin, JN2
Rinehart, BK2
May, WL2
Magann, EF2
Terrone, DA2
Blake, PG2
Merrin, C1
Higgins, GR1
Jamin, DC1
Shore, NA1
Momparler, R1
Hartman, G1
Siegel, SE1
Dubiel, W1
Happle, R1
Berg, G1
Matzkies, F1
Bickel, H1
Zeilhofer, R1
Perheentupa, J1
Raivio, KO1
Nikkilä, EA1
Rossof, AH1
Slayton, RE1
Perlia, CP1
Hutchison, JC1
Holmes, EL1
Oettgen, HF1
Stephenson, PA1
Schwartz, MK1
Leeper, RD1
Tallai, L1
Tan, CC1
Clarkson, BD1
Golbey, RB1
Krakoff, IH1
Karnofsky, DA1
Murphy, ML1
Burchenal, JH1
Gifford, RW1
Harvengt, C1
Lavenne, F1
Storti, E1
Quaglino, D1
Barbeau, A1
Mars, H1
Gillo-Joffroy, L1
Paulus, HE1
Coutts, A1
Calabro, JJ1
Klinenberg, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III, Multi-center, Open Label, Flexible Dose, Long Term Safety Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia[NCT00772382]Phase 3116 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Change in Serum Phosphorus From Baseline to Week 52

(NCT00772382)
Timeframe: 52 weeks

Interventionmg/dL (Mean)
MCI-196-1.18

Number of Adverse Events (AE)

(NCT00772382)
Timeframe: 52 weeks

Interventionparticipants (Number)
At least 1 treatment-emergent AEAt least 1 drug-related treatment-emergent AEAt least 1 treatment-emergent serious AE
MCI-1961095063

Reviews

2 reviews available for uric acid and Emesis

ArticleYear
CHELATION THERAPY OF OCCLUSIVE ARTERIOSCLEROSIS IN DIABETIC PATIENTS.
    Angiology, 1964, Volume: 15

    Topics: Aged; Arteriosclerosis; Blood Urea Nitrogen; Chelation Therapy; Dermatitis; Diabetes Mellitus; Diabe

1964
Hereditary fructose intolerance.
    Acta medica Scandinavica. Supplementum, 1972, Volume: 542

    Topics: 17-Ketosteroids; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Cholesterol; Diet The

1972

Trials

8 trials available for uric acid and Emesis

ArticleYear
Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia.
    Blood purification, 2016, Volume: 41, Issue:4

    Topics: Adult; Aged; Bile Acids and Salts; Cholesterol, LDL; Diarrhea; Female; Glycated Hemoglobin; Hemodial

2016
Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:11

    Topics: Aged; Aged, 80 and over; Bone Density; Calcium; Collagen; Collagen Type I; Creatine; Double-Blind Me

2005
Does allopurinol reduce pain of chronic pancreatitis?
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1997, Volume: 22, Issue:3

    Topics: Abdominal Pain; Activities of Daily Living; Adult; Allopurinol; Ankle; Blood Cell Count; Chronic Dis

1997
[Experimental treatment with fumaric acid monoethylester in psoriasis vulgaris].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, Jul-01, Volume: 47, Issue:13

    Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Eruptio

1972
The hypotensive action of ethacrynic acid.
    Vascular diseases, 1968, Volume: 5, Issue:2

    Topics: Abdomen; Adult; Aged; Antihypertensive Agents; Black People; Blood Glucose; Blood Pressure Determina

1968
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. IV. Toleration by normal human subjects.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Biphenyl Compounds; Blood Coagulation; Blood Urea Nitrogen

1966
Ethacrynic acid alone and in combination with methyldopa in the management of mild hypertension. A report of 23 patients.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:3

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diarrhea; Drug Synergism; Ethacrynic Acid; Fe

1970
[Influence of aluminum nicotinate on serum lipids].
    Acta cardiologica, 1969, Volume: 24, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aluminum; Arteriosclerosis; Blood Glucose; Cardiovascular Diseases; Cho

1969

Other Studies

17 other studies available for uric acid and Emesis

ArticleYear
Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report.
    Medicine, 2020, Aug-21, Volume: 99, Issue:34

    Topics: Administration, Intravenous; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Humans; Hy

2020
[Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome].
    Gynecologie, obstetrique & fertilite, 2004, Volume: 32, Issue:9

    Topics: Adult; Female; Gestational Age; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Uric

2004
Regimen of indomethacin therapy in acute gouty arthritis.
    British medical journal, 1967, Apr-29, Volume: 2, Issue:5547

    Topics: Adult; Creatine; Female; Gout; Headache; Humans; Indomethacin; Male; Middle Aged; Nausea; Urea; Uric

1967
[Headache and EEG changes caused by acetate and bicarbonate dialysis].
    Acta medica Austriaca, 1983, Volume: 10, Issue:1

    Topics: Acetates; Acid-Base Equilibrium; Adult; Bicarbonates; Electroencephalography; Headache; Humans; Naus

1983
[Female gout disclosing Bartter pseudo-syndrome caused by vomiting].
    La Revue de medecine interne, 1993, Volume: 14, Issue:3

    Topics: Adult; Bartter Syndrome; Diagnosis, Differential; Female; Gout; Humans; Uric Acid; Vomiting

1993
Disease-specific noncompliance with drug treatment as a cause of persistent hyperuricemia and gout in anorexia nervosa.
    European journal of medical research, 1998, Feb-21, Volume: 3, Issue:1-2

    Topics: Allopurinol; Anorexia Nervosa; Female; Gout; Humans; Middle Aged; Patient Compliance; Treatment Fail

1998
Surgical treatment of urate calculi in Dalmatians: 38 cases (1980-1995).
    Journal of the American Veterinary Medical Association, 1998, Sep-15, Volume: 213, Issue:6

    Topics: Animals; Bacteriuria; Blood Chemical Analysis; Dog Diseases; Dogs; Female; Hematuria; Male; Retrospe

1998
The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:6 Pt 1

    Topics: Aspartate Aminotransferases; Birth Weight; Cesarean Section; Eclampsia; Female; Fetal Death; Headach

1999
Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:6 Pt 1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Creatinine; Female; HELLP Syndrome; Humans; L-Lac

1999
Treatment of advanced bladder cancer with cis-diamminedichloroplatinum (II NSC 119875): a pilot study.
    The Journal of urology, 1978, Volume: 119, Issue:4

    Topics: Carcinoma, Transitional Cell; Cisplatin; Female; Humans; Leukopenia; Male; Nausea; Neoplasm Metastas

1978
Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Acute Disease; Acute Kidney Injury; Child; Deoxyguanosine; Drug Evaluation; Humans; Leukemia; Leukem

1985
[Acid-base equilibrium in long-term infusions of xylitol, fructose, glucose and carbohydrate mixtures].
    Zeitschrift fur Ernahrungswissenschaft. Journal of nutritional sciences. Supplementa, 1973, Volume: 15

    Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Blood; Carbon Dioxide; Carbonates; Chlorides; Drug Inter

1973
Preliminary clinical experience with cis-diamminedichloroplatinum (II) (NSC 119875, CACP).
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Amines; Anemia; Antineoplastic Agents; Audiometry; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cel

1972
Toxicity of E. coli L-asparaginase in man.
    Cancer, 1970, Volume: 25, Issue:2

    Topics: Adult; Agranulocytosis; Antigen-Antibody Reactions; Asparaginase; Blood Platelet Disorders; Bone Mar

1970
Dysmetabolic and neurological complications in leukemia patients treated with L-asparaginase.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Asparaginase; Central Nervous System Diseases; Child; Clinical Enzyme Tests; Drug Hypersensitivity;

1970
Adverse clinical side effects of levodopa therapy.
    Contemporary neurology series, 1971, Volume: 8

    Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede

1971
Clinical significance of hyperuricemia in routinely screened hospitalized men.
    JAMA, 1970, Jan-12, Volume: 211, Issue:2

    Topics: Acidosis; Adult; Aged; Autoanalysis; Diuretics; Gout; Heart Failure; Hospitalization; Humans; Kidney

1970