uric acid and Emesis
uric acid has been researched along with Emesis in 27 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis." | 9.08 | Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997) |
| "Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances." | 7.96 | Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020) |
| "We report five cases of vomiting associated with a very important increase of maternal plasma uric acid (> 595 mmol/l, 100 mg/l) at the third trimester of pregnancy." | 7.72 | [Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome]. ( Bresson-Just, S; Codaccioni, X; Herchin-Decobert, A; Houfflin-Debarge, V; Moranne, O; Subtil, D, 2004) |
| "Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks." | 7.67 | Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985) |
| "A dosage of 300 mg/d of allopurinol was not effective in reducing pain or improving activities of daily living in chronic pancreatitis." | 5.08 | Does allopurinol reduce pain of chronic pancreatitis? ( Banks, PA; Ferrante, M; Hughes, M; Noordhoek, EC; Ramagopal, V; Slivka, A, 1997) |
| "Lesch-Nyhan syndrome (LNS) is an X-linked recessive disorder presenting with uric acid overproduction, neurocognitive disability, and behavioral disturbances." | 3.96 | Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report. ( Jeon, S; Jung, SM; Lee, J, 2020) |
| "We report five cases of vomiting associated with a very important increase of maternal plasma uric acid (> 595 mmol/l, 100 mg/l) at the third trimester of pregnancy." | 3.72 | [Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome]. ( Bresson-Just, S; Codaccioni, X; Herchin-Decobert, A; Houfflin-Debarge, V; Moranne, O; Subtil, D, 2004) |
| "The presence of nausea and vomiting, epigastric pain, or both in association with admission laboratory values that are in excess of the cutoffs for lactate dehydrogenase, aspartate aminotransferase, and uric acid concentrations or for all 6 tests is predictive of high risk of morbidity for the patient with severe preeclampsia." | 3.70 | Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999) |
| "Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks." | 3.67 | Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia. ( Hartman, G; Higgins, GR; Jamin, DC; Momparler, R; Shore, NA; Siegel, SE, 1985) |
| "Long-term flexible dosing with colestilan reduces serum phosphorus and demonstrates an acceptable safety and tolerability profile." | 2.82 | Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia. ( Dimkovic, N; Locatelli, F; Spasovski, G; Wanner, C, 2016) |
| "Hematuria was found in 85% of dogs in which urinalysis was performed." | 1.30 | Surgical treatment of urate calculi in Dalmatians: 38 cases (1980-1995). ( Birchard, SJ; Chew, DJ; Collins, RL; Heuter, KJ, 1998) |
| "Class 3 HELLP syndrome is considered a clinically significant transitional group." | 1.30 | The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification. ( Blake, PG; Magann, EF; Martin, JN; May, WL; Rinehart, BK; Terrone, DA, 1999) |
Research
Studies (27)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (62.96) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lee, J | 1 |
| Jung, SM | 1 |
| Jeon, S | 1 |
| Locatelli, F | 1 |
| Spasovski, G | 1 |
| Dimkovic, N | 1 |
| Wanner, C | 1 |
| LAMAR, CP | 1 |
| Bresson-Just, S | 1 |
| Houfflin-Debarge, V | 1 |
| Herchin-Decobert, A | 1 |
| Moranne, O | 1 |
| Codaccioni, X | 1 |
| Subtil, D | 1 |
| Deal, C | 1 |
| Omizo, M | 1 |
| Schwartz, EN | 1 |
| Eriksen, EF | 1 |
| Cantor, P | 1 |
| Wang, J | 1 |
| Glass, EV | 1 |
| Myers, SL | 1 |
| Krege, JH | 1 |
| Emmerson, BT | 1 |
| Neyer, U | 1 |
| Wöss, E | 1 |
| Haller, R | 1 |
| Kröss, R | 1 |
| Jacobs, F | 1 |
| Hurault de Ligny, B | 1 |
| Le Goff, C | 1 |
| Ryckelynck, JP | 1 |
| Banks, PA | 1 |
| Hughes, M | 1 |
| Ferrante, M | 1 |
| Noordhoek, EC | 1 |
| Ramagopal, V | 1 |
| Slivka, A | 1 |
| Gröbner, W | 1 |
| Walter-Sack, I | 1 |
| de Vries, JX | 1 |
| Collins, RL | 1 |
| Birchard, SJ | 1 |
| Chew, DJ | 1 |
| Heuter, KJ | 1 |
| Martin, JN | 2 |
| Rinehart, BK | 2 |
| May, WL | 2 |
| Magann, EF | 2 |
| Terrone, DA | 2 |
| Blake, PG | 2 |
| Merrin, C | 1 |
| Higgins, GR | 1 |
| Jamin, DC | 1 |
| Shore, NA | 1 |
| Momparler, R | 1 |
| Hartman, G | 1 |
| Siegel, SE | 1 |
| Dubiel, W | 1 |
| Happle, R | 1 |
| Berg, G | 1 |
| Matzkies, F | 1 |
| Bickel, H | 1 |
| Zeilhofer, R | 1 |
| Perheentupa, J | 1 |
| Raivio, KO | 1 |
| Nikkilä, EA | 1 |
| Rossof, AH | 1 |
| Slayton, RE | 1 |
| Perlia, CP | 1 |
| Hutchison, JC | 1 |
| Holmes, EL | 1 |
| Oettgen, HF | 1 |
| Stephenson, PA | 1 |
| Schwartz, MK | 1 |
| Leeper, RD | 1 |
| Tallai, L | 1 |
| Tan, CC | 1 |
| Clarkson, BD | 1 |
| Golbey, RB | 1 |
| Krakoff, IH | 1 |
| Karnofsky, DA | 1 |
| Murphy, ML | 1 |
| Burchenal, JH | 1 |
| Gifford, RW | 1 |
| Harvengt, C | 1 |
| Lavenne, F | 1 |
| Storti, E | 1 |
| Quaglino, D | 1 |
| Barbeau, A | 1 |
| Mars, H | 1 |
| Gillo-Joffroy, L | 1 |
| Paulus, HE | 1 |
| Coutts, A | 1 |
| Calabro, JJ | 1 |
| Klinenberg, JR | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III, Multi-center, Open Label, Flexible Dose, Long Term Safety Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia[NCT00772382] | Phase 3 | 116 participants (Actual) | Interventional | 2008-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
The Change in Serum Phosphorus From Baseline to Week 52
(NCT00772382)
Timeframe: 52 weeks
| Intervention | mg/dL (Mean) |
|---|---|
| MCI-196 | -1.18 |
Number of Adverse Events (AE)
(NCT00772382)
Timeframe: 52 weeks
| Intervention | participants (Number) | ||
|---|---|---|---|
| At least 1 treatment-emergent AE | At least 1 drug-related treatment-emergent AE | At least 1 treatment-emergent serious AE | |
| MCI-196 | 109 | 50 | 63 |
Reviews
2 reviews available for uric acid and Emesis
| Article | Year |
|---|---|
CHELATION THERAPY OF OCCLUSIVE ARTERIOSCLEROSIS IN DIABETIC PATIENTS.
Topics: Aged; Arteriosclerosis; Blood Urea Nitrogen; Chelation Therapy; Dermatitis; Diabetes Mellitus; Diabe | 1964 |
Hereditary fructose intolerance.
Topics: 17-Ketosteroids; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; Cholesterol; Diet The | 1972 |
Trials
8 trials available for uric acid and Emesis
| Article | Year |
|---|---|
Long-Term Evaluation of Colestilan in Chronic Kidney Disease Stage 5 Dialysis Patients with Hyperphosphataemia.
Topics: Adult; Aged; Bile Acids and Salts; Cholesterol, LDL; Diarrhea; Female; Glycated Hemoglobin; Hemodial | 2016 |
Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Bone Density; Calcium; Collagen; Collagen Type I; Creatine; Double-Blind Me | 2005 |
Does allopurinol reduce pain of chronic pancreatitis?
Topics: Abdominal Pain; Activities of Daily Living; Adult; Allopurinol; Ankle; Blood Cell Count; Chronic Dis | 1997 |
[Experimental treatment with fumaric acid monoethylester in psoriasis vulgaris].
Topics: Administration, Oral; Adult; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Eruptio | 1972 |
The hypotensive action of ethacrynic acid.
Topics: Abdomen; Adult; Aged; Antihypertensive Agents; Black People; Blood Glucose; Blood Pressure Determina | 1968 |
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. IV. Toleration by normal human subjects.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Biphenyl Compounds; Blood Coagulation; Blood Urea Nitrogen | 1966 |
Ethacrynic acid alone and in combination with methyldopa in the management of mild hypertension. A report of 23 patients.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diarrhea; Drug Synergism; Ethacrynic Acid; Fe | 1970 |
[Influence of aluminum nicotinate on serum lipids].
Topics: Adult; Alkaline Phosphatase; Aluminum; Arteriosclerosis; Blood Glucose; Cardiovascular Diseases; Cho | 1969 |
Other Studies
17 other studies available for uric acid and Emesis
| Article | Year |
|---|---|
Delayed emergence from propofol anesthesia in a patient with Lesch-Nyhan syndrome: A case report.
Topics: Administration, Intravenous; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Humans; Hy | 2020 |
[Important elevation of uric acid associated with vomiting at the third trimester of pregnancy: report of five cases with favorable outcome].
Topics: Adult; Female; Gestational Age; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Uric | 2004 |
Regimen of indomethacin therapy in acute gouty arthritis.
Topics: Adult; Creatine; Female; Gout; Headache; Humans; Indomethacin; Male; Middle Aged; Nausea; Urea; Uric | 1967 |
[Headache and EEG changes caused by acetate and bicarbonate dialysis].
Topics: Acetates; Acid-Base Equilibrium; Adult; Bicarbonates; Electroencephalography; Headache; Humans; Naus | 1983 |
[Female gout disclosing Bartter pseudo-syndrome caused by vomiting].
Topics: Adult; Bartter Syndrome; Diagnosis, Differential; Female; Gout; Humans; Uric Acid; Vomiting | 1993 |
Disease-specific noncompliance with drug treatment as a cause of persistent hyperuricemia and gout in anorexia nervosa.
Topics: Allopurinol; Anorexia Nervosa; Female; Gout; Humans; Middle Aged; Patient Compliance; Treatment Fail | 1998 |
Surgical treatment of urate calculi in Dalmatians: 38 cases (1980-1995).
Topics: Animals; Bacteriuria; Blood Chemical Analysis; Dog Diseases; Dogs; Female; Hematuria; Male; Retrospe | 1998 |
The spectrum of severe preeclampsia: comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification.
Topics: Aspartate Aminotransferases; Birth Weight; Cesarean Section; Eclampsia; Female; Fetal Death; Headach | 1999 |
Early risk assessment of severe preeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Creatinine; Female; HELLP Syndrome; Humans; L-Lac | 1999 |
Treatment of advanced bladder cancer with cis-diamminedichloroplatinum (II NSC 119875): a pilot study.
Topics: Carcinoma, Transitional Cell; Cisplatin; Female; Humans; Leukopenia; Male; Nausea; Neoplasm Metastas | 1978 |
Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia.
Topics: Acute Disease; Acute Kidney Injury; Child; Deoxyguanosine; Drug Evaluation; Humans; Leukemia; Leukem | 1985 |
[Acid-base equilibrium in long-term infusions of xylitol, fructose, glucose and carbohydrate mixtures].
Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Blood; Carbon Dioxide; Carbonates; Chlorides; Drug Inter | 1973 |
Preliminary clinical experience with cis-diamminedichloroplatinum (II) (NSC 119875, CACP).
Topics: Amines; Anemia; Antineoplastic Agents; Audiometry; Blood Urea Nitrogen; Bone Marrow; Bone Marrow Cel | 1972 |
Toxicity of E. coli L-asparaginase in man.
Topics: Adult; Agranulocytosis; Antigen-Antibody Reactions; Asparaginase; Blood Platelet Disorders; Bone Mar | 1970 |
Dysmetabolic and neurological complications in leukemia patients treated with L-asparaginase.
Topics: Asparaginase; Central Nervous System Diseases; Child; Clinical Enzyme Tests; Drug Hypersensitivity; | 1970 |
Adverse clinical side effects of levodopa therapy.
Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede | 1971 |
Clinical significance of hyperuricemia in routinely screened hospitalized men.
Topics: Acidosis; Adult; Aged; Autoanalysis; Diuretics; Gout; Heart Failure; Hospitalization; Humans; Kidney | 1970 |