uric acid and Edema
uric acid has been researched along with Edema in 99 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacodynamics of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea), a new potent loop diuretic, were compared to those of furosemide in a double-blind controlled study in 18 patients with oedema of various origin." | 9.06 | Comparative pharmacodynamics of torasemide and furosemide in patients with oedema. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1988) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 9.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "We aimed to clarify whether a RSG extract attenuates hyperuricemia, paw edema, and renal injury in mice with potassium oxonate (PO)- and monosodium urate (MSU)-induced chronic hyperuricemia and gout." | 7.91 | Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019) |
| "The present study suggests that luteolin and luteolin-4'-O-glucoside could be developed as therapeutics for treating hyperuricemia and gouty arthritis." | 7.88 | Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. ( Hu, YJ; Liang, WQ; Lin, Y; Liu, PG; Pu, JB; Xu, P; Zhang, HJ; Zhou, J, 2018) |
| "In the joint homogenate of rats with MSU crystal-induced inflammation, treatment with ferulic acid (30mg/kg body weight (b." | 7.83 | Targeting inflammatory mediators with ferulic acid, a dietary polyphenol, for the suppression of monosodium urate crystal-induced inflammation in rats. ( Dey, C; Doss, HM; Rasool, MK; Sudandiradoss, C, 2016) |
| "Taken together, our results show that MSU-induced gouty arthritis is accompanied by osteoclast-related protein upregulation and that lemnalol treatment may be beneficial for the attenuation of MC infiltration and degranulation and for suppressing osteoclast activation in gouty arthritis." | 7.81 | Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. ( Duh, CY; Huang, SY; Jean, YH; Lee, HP; Lin, SC; Lin, YY; Wang, HM; Wen, ZH; Wu, SF, 2015) |
| " In the present study, we found that treatment with lemnalol (intramuscular [im]), but not colchicine (oral [po]), significantly attenuated MUS-induced mechanical allodynia, paw edema and knee swelling." | 7.79 | Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. ( Duh, CY; Huang, SY; Jean, YH; Lee, HP; Lin, YY; Wang, HM; Wen, ZH; Wu, SF, 2013) |
| "Quercetin treatment attenuated oedema in a dose-dependent manner and decreased histological signs of acute inflammation in the treated animals." | 7.78 | Therapeutic properties of quercetin on monosodium urate crystal-induced inflammation in rat. ( Chen, J; Huang, J; Li, S; Sun, W; Tao, Y; Wang, S; Zhu, M, 2012) |
| "The effects of indomethacin on the production of cytokines at inflammatory sites were investigated in the monosodium urate (MSU) pleurisy model characterized by both cellular influx and edema." | 7.69 | Inhibitory action of indomethacin on neutrophil infiltration in monosodium urate-induced pleurisy in rats. ( Aihara, S; Murakami, N; Namba, K; Naruse, T; Tomita, T, 1995) |
| "The pharmacodynamics of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea), a new potent loop diuretic, were compared to those of furosemide in a double-blind controlled study in 18 patients with oedema of various origin." | 5.06 | Comparative pharmacodynamics of torasemide and furosemide in patients with oedema. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1988) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 5.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "The pharmacodynamic effects of torasemide, a new potent loop diuretic, were compared with those of furosemide in a double blind controlled study in 18 hypertensive patients with oedema of various origins." | 5.06 | Torasemide, a new potent diuretic. Double-blind comparison with furosemide. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1986) |
| "Compared to hyperuricaemia model or acute gout model, the compound gout model showed little advantages of elevating serum uric acid, causing foot swelling and gout inflammation, while it caused more severe serum inflammation and gut microbiota dysbiosis." | 3.96 | Combined effects of MSU crystals injection and high fat-diet feeding on the establishment of a gout model in C57BL/6 mice. ( He, Z; Lin, X; Shao, T; Wang, M; Wen, C; Wen, X, 2020) |
| "We aimed to clarify whether a RSG extract attenuates hyperuricemia, paw edema, and renal injury in mice with potassium oxonate (PO)- and monosodium urate (MSU)-induced chronic hyperuricemia and gout." | 3.91 | Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice. ( Chang, Y; Liang, C; Liang, G; Nie, Y; Xiao, D; Zeng, S; Zhan, S; Zheng, Q; Zheng, X, 2019) |
| "The present study suggests that luteolin and luteolin-4'-O-glucoside could be developed as therapeutics for treating hyperuricemia and gouty arthritis." | 3.88 | Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models. ( Hu, YJ; Liang, WQ; Lin, Y; Liu, PG; Pu, JB; Xu, P; Zhang, HJ; Zhou, J, 2018) |
| " affine extract was evaluated in an experimental model with potassium oxonate (PO) induced hyperuricemia in mice which was used to evaluate anti-hyperuricemia activity and xanthine oxidase (XO) inhibition." | 3.85 | Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis. ( Cheng, L; Hu, YJ; Li, LN; Liang, WQ; Liu, PG; Pu, JB; Xu, P; Yang, QQ; Zhang, HJ; Zhang, YQ; Zhou, J, 2017) |
| "In the joint homogenate of rats with MSU crystal-induced inflammation, treatment with ferulic acid (30mg/kg body weight (b." | 3.83 | Targeting inflammatory mediators with ferulic acid, a dietary polyphenol, for the suppression of monosodium urate crystal-induced inflammation in rats. ( Dey, C; Doss, HM; Rasool, MK; Sudandiradoss, C, 2016) |
| "Taken together, our results show that MSU-induced gouty arthritis is accompanied by osteoclast-related protein upregulation and that lemnalol treatment may be beneficial for the attenuation of MC infiltration and degranulation and for suppressing osteoclast activation in gouty arthritis." | 3.81 | Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. ( Duh, CY; Huang, SY; Jean, YH; Lee, HP; Lin, SC; Lin, YY; Wang, HM; Wen, ZH; Wu, SF, 2015) |
| " In the present study, we found that treatment with lemnalol (intramuscular [im]), but not colchicine (oral [po]), significantly attenuated MUS-induced mechanical allodynia, paw edema and knee swelling." | 3.79 | Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. ( Duh, CY; Huang, SY; Jean, YH; Lee, HP; Lin, YY; Wang, HM; Wen, ZH; Wu, SF, 2013) |
| "Quercetin treatment attenuated oedema in a dose-dependent manner and decreased histological signs of acute inflammation in the treated animals." | 3.78 | Therapeutic properties of quercetin on monosodium urate crystal-induced inflammation in rat. ( Chen, J; Huang, J; Li, S; Sun, W; Tao, Y; Wang, S; Zhu, M, 2012) |
| "The effects of indomethacin on the production of cytokines at inflammatory sites were investigated in the monosodium urate (MSU) pleurisy model characterized by both cellular influx and edema." | 3.69 | Inhibitory action of indomethacin on neutrophil infiltration in monosodium urate-induced pleurisy in rats. ( Aihara, S; Murakami, N; Namba, K; Naruse, T; Tomita, T, 1995) |
| "The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis." | 3.68 | Evaluation of hemodialysis efficiency by an edema fluid model. ( Fujita, Y; Izumi, M; Kajimoto, Y; Nakahama, H; Ochi, S; Shirai, D; Tanaka, Y; Wada, A; Yano, F, 1992) |
| "The pathogenesis of burn edema in the skin of rats appears to be related to a role for histamine, xanthine oxidase and oxygen radicals." | 3.67 | Roles of histamine, complement and xanthine oxidase in thermal injury of skin. ( Friedl, HP; Till, GO; Trentz, O; Ward, PA, 1989) |
| " These changes include hydronephrosis, decreased BUN and uric acid, proteinuria and glycosuria (70 percent one time), frequency, nocturia, edema (80 percent) and reductions in blood pressure." | 3.66 | The kidney and pregnancy. ( Chester, AC; Harris, JP; Schreiner, GE, 1978) |
| "The primary outcomes will be joint pain measured by VAS score, and joint swelling measured using width and thickness of affected joints and VAS score." | 3.11 | Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial. ( Dong, X; Huang, JY; Li, XP; Liu, JP; Liu, Y; Shang, YX; Wang, XC; Wei, SF; Xie, ZM, 2022) |
| "Xipamide is a diuretic derived from salicylic acid and has a structural resemblance to chlorthalidone." | 2.37 | Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. ( Brogden, RN; Prichard, BN, 1985) |
| "Gouty arthritis is characterized by painful inflammation due to the deposition of monosodium urate crystals in joint tissues." | 1.91 | Articular mobilization promotes improvement in functional and inflammatory parameters in a gouty arthritis model. ( Bertolini, GRF; Costa, RM; Hoss, IM; Leal, TSDS; Pradal, LA; Ribeiro, LFC, 2023) |
| "Mechanical hyperalgesia was conducted using the electronic von Frey." | 1.72 | Regulation of TRPV1 channel in monosodium urate-induced gouty arthritis in mice. ( Li, G; Xu, X; Yuan, Z; Zhang, G; Zhang, S, 2022) |
| "Gout is sterile joint inflammation triggered by the damaging effects of monosodium urate (MSU) crystals accumulation." | 1.51 | Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation. ( He, YL; Mi, QS; Yang, QB; Zhang, QB; Zhou, JG, 2019) |
| "Etiology of preeclampsia is still largely unraveled and treatment is syndrome specific." | 1.31 | [Twin pregnancy and preeclampsia]. ( Leszczyńska-Gorzelak, B; Oleszczuk, JJ; Szymczyk, G, 2000) |
| " Uric acid clearance did not show any appreciable change after long-term administration of ticrynafen." | 1.26 | A case of familial renal hypouricemia associated with increased secretion of para-aminohippurate and idiopathic edema. ( Aonuma, K; Ito, Y; Matsuda, O; Shiigai, T; Takeuchi, J, 1982) |
| "Forty patients with generalized cancer complicated by water and electrolyte retention were treated with "medium" and "large" doses of furosemide and bumetanide with 35% and 40% objective positive response, respectively." | 1.26 | Diuretics in malignant effusions and edemas of generalized cancer. ( Athanasiou, A; Dadiotis, L; Razis, DV, 1976) |
| "Nine cases of chronic lymphocytic leukemia (CLL) served as controls." | 1.25 | Pathoanatomical features of the kidney in myelomonocytic and chronic lymphocytic leukemia. ( Schwarze, EW, 1975) |
Research
Studies (99)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (60.61) | 18.7374 |
| 1990's | 2 (2.02) | 18.2507 |
| 2000's | 4 (4.04) | 29.6817 |
| 2010's | 19 (19.19) | 24.3611 |
| 2020's | 14 (14.14) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Goo, B | 1 |
| Lee, J | 1 |
| Park, C | 1 |
| Yune, T | 1 |
| Park, Y | 1 |
| Xu, X | 1 |
| Yuan, Z | 2 |
| Zhang, S | 1 |
| Li, G | 1 |
| Zhang, G | 1 |
| Shang, YX | 1 |
| Dong, X | 1 |
| Xie, ZM | 1 |
| Li, XP | 1 |
| Wang, XC | 1 |
| Huang, JY | 1 |
| Wei, SF | 1 |
| Liu, Y | 1 |
| Liu, JP | 1 |
| Xu, W | 1 |
| Li, F | 1 |
| Zhang, X | 3 |
| Wu, C | 1 |
| Wang, Y | 3 |
| Yao, Y | 1 |
| Xia, D | 1 |
| Sun, Z | 1 |
| Li, Z | 1 |
| Tan, Y | 1 |
| Wang, X | 1 |
| Wang, C | 1 |
| Dong, M | 1 |
| Liu, H | 1 |
| Chen, H | 1 |
| Li, Y | 2 |
| Li, L | 1 |
| Wang, D | 1 |
| Abedi, B | 1 |
| Tayebi Khosroshahi, H | 1 |
| Hoss, IM | 1 |
| Pradal, LA | 1 |
| Leal, TSDS | 1 |
| Bertolini, GRF | 1 |
| Costa, RM | 1 |
| Ribeiro, LFC | 1 |
| Liu, F | 1 |
| Shen, F | 2 |
| Bai, Y | 1 |
| Wan, Y | 1 |
| Zheng, L | 1 |
| He, J | 1 |
| Xie, Y | 2 |
| Guo, P | 1 |
| Marinho, Y | 1 |
| Marques-da-Silva, C | 1 |
| Santana, PT | 1 |
| Chaves, MM | 1 |
| Tamura, AS | 1 |
| Rangel, TP | 1 |
| Gomes-E-Silva, IV | 1 |
| Guimarães, MZP | 1 |
| Coutinho-Silva, R | 1 |
| Liu, N | 2 |
| Zeng, L | 2 |
| Yin, S | 2 |
| Hu, Y | 2 |
| Li, S | 3 |
| Fu, Y | 2 |
| Xie, C | 2 |
| Shu, L | 2 |
| Sun, H | 1 |
| Yang, M | 2 |
| Sun, J | 1 |
| Yang, X | 2 |
| Lin, X | 1 |
| Shao, T | 1 |
| Wen, X | 1 |
| Wang, M | 1 |
| Wen, C | 1 |
| He, Z | 1 |
| Meng, B | 1 |
| Shi, L | 2 |
| Liu, J | 1 |
| Cai, R | 1 |
| Hasnat, M | 1 |
| Yu, H | 1 |
| Feng, J | 1 |
| Wang, Z | 1 |
| Zhao, Q | 1 |
| Wu, M | 1 |
| Huang, X | 1 |
| Yin, L | 2 |
| Yu, Y | 1 |
| Liang, T | 1 |
| Yang, J | 1 |
| Chen, G | 1 |
| Guo, TW | 1 |
| Qin, WY | 1 |
| Jia, P | 1 |
| Zhang, HJ | 2 |
| Li, LN | 1 |
| Zhou, J | 2 |
| Yang, QQ | 1 |
| Liu, PG | 2 |
| Xu, P | 2 |
| Liang, WQ | 2 |
| Cheng, L | 1 |
| Zhang, YQ | 1 |
| Pu, JB | 2 |
| Hu, YJ | 2 |
| Lee, YM | 1 |
| Shon, EJ | 1 |
| Kim, OS | 1 |
| Kim, DS | 1 |
| Lin, Y | 1 |
| Liang, G | 1 |
| Nie, Y | 1 |
| Chang, Y | 1 |
| Zeng, S | 1 |
| Liang, C | 1 |
| Zheng, X | 1 |
| Xiao, D | 1 |
| Zhan, S | 1 |
| Zheng, Q | 1 |
| Yang, TH | 1 |
| Yan, DX | 1 |
| Huang, XY | 1 |
| Hou, B | 1 |
| Ma, YB | 1 |
| Peng, H | 1 |
| Zhang, XM | 1 |
| Chen, JJ | 1 |
| Geng, CA | 1 |
| Yang, QB | 1 |
| He, YL | 1 |
| Zhang, QB | 1 |
| Mi, QS | 1 |
| Zhou, JG | 1 |
| Kodithuwakku, ND | 1 |
| Pan, M | 1 |
| Zhu, YL | 1 |
| Zhang, YY | 1 |
| Feng, YD | 1 |
| Fang, WR | 1 |
| Li, YM | 1 |
| Xu, L | 1 |
| Yang, Y | 1 |
| Song, H | 1 |
| Pan, H | 1 |
| Silva, CR | 2 |
| Oliveira, SM | 2 |
| Hoffmeister, C | 2 |
| Funck, V | 1 |
| Guerra, GP | 1 |
| Trevisan, G | 3 |
| Tonello, R | 1 |
| Rossato, MF | 3 |
| Pesquero, JB | 1 |
| Bader, M | 1 |
| Oliveira, MS | 1 |
| McDougall, JJ | 1 |
| Ferreira, J | 3 |
| Lee, HP | 2 |
| Lin, YY | 2 |
| Duh, CY | 2 |
| Huang, SY | 2 |
| Wang, HM | 2 |
| Wu, SF | 2 |
| Lin, SC | 1 |
| Jean, YH | 2 |
| Wen, ZH | 2 |
| Doss, HM | 1 |
| Dey, C | 1 |
| Sudandiradoss, C | 1 |
| Rasool, MK | 1 |
| Han, J | 1 |
| Sui, F | 1 |
| Liu, C | 2 |
| Du, X | 1 |
| Feng, X | 1 |
| Jiang, D | 1 |
| Udhaya Lavinya, B | 1 |
| Bardhan, I | 1 |
| Evan Prince, S | 1 |
| Mallinson, PI | 1 |
| Coupal, TM | 1 |
| McLaughlin, PD | 1 |
| Nicolaou, S | 1 |
| Munk, PL | 1 |
| Ouellette, HA | 1 |
| Sabina, EP | 1 |
| Rasool, M | 1 |
| Mathew, L | 1 |
| Ezilrani, P | 1 |
| Indu, H | 1 |
| de Oliveira, SM | 1 |
| Gomez, MV | 1 |
| Huang, J | 1 |
| Zhu, M | 1 |
| Tao, Y | 1 |
| Wang, S | 1 |
| Chen, J | 1 |
| Sun, W | 1 |
| Fröhlich, JK | 1 |
| Cabreira, TN | 1 |
| Froeder, AL | 1 |
| Bochi, GV | 1 |
| Moresco, RN | 1 |
| Athayde, ML | 1 |
| CAPRAMARZANI, P | 1 |
| SALISBURY, PF | 1 |
| POMERANZ, AA | 1 |
| SIEGEL, I | 1 |
| BENCOMO, L | 1 |
| FYVOLENT, J | 1 |
| KAHANA, S | 1 |
| KAHANA, L | 1 |
| Zare, F | 1 |
| Magnusson, M | 1 |
| Bergström, T | 1 |
| Brisslert, M | 1 |
| Josefsson, E | 1 |
| Karlsson, A | 1 |
| Tarkowski, A | 1 |
| Liamis, G | 1 |
| Christidis, D | 1 |
| Alexandridis, G | 1 |
| Bairaktari, E | 1 |
| Madias, NE | 1 |
| Elisaf, M | 1 |
| Liu, L | 1 |
| Inoue, H | 1 |
| Nakayama, H | 1 |
| Kanno, R | 1 |
| Kanno, M | 1 |
| Angelopoulos, B | 1 |
| Vlassopoulos, C | 1 |
| Kalos, A | 2 |
| Kopp, H | 1 |
| Frank, H | 1 |
| Lundvall, O | 1 |
| Berlind, S | 1 |
| Phelps, P | 1 |
| McCarty, DJ | 1 |
| Daniel, A | 1 |
| Jouvin, JL | 1 |
| Damas, J | 1 |
| Remacle-Volon, G | 1 |
| Adam, A | 1 |
| Mihindukulasuriya, J | 1 |
| Lee, HA | 1 |
| Chang, YH | 1 |
| Bluestone, R | 1 |
| Matsuda, O | 1 |
| Shiigai, T | 1 |
| Ito, Y | 1 |
| Aonuma, K | 1 |
| Takeuchi, J | 1 |
| Aihara, S | 1 |
| Murakami, N | 1 |
| Tomita, T | 1 |
| Naruse, T | 1 |
| Namba, K | 1 |
| Leszczyńska-Gorzelak, B | 1 |
| Szymczyk, G | 1 |
| Oleszczuk, JJ | 1 |
| Maeda, M | 1 |
| Tanaka, Y | 2 |
| Suzuki, T | 1 |
| Nakamura, K | 1 |
| Harris, JP | 1 |
| Chester, AC | 1 |
| Schreiner, GE | 1 |
| Schwarze, EW | 1 |
| Razis, DV | 1 |
| Athanasiou, A | 1 |
| Dadiotis, L | 1 |
| Redman, CW | 1 |
| Bonnar, J | 1 |
| Beilin, LJ | 1 |
| McNeilly, AS | 1 |
| Bosl, R | 1 |
| Shideman, JR | 1 |
| Meyer, RM | 1 |
| Buselmeier, TJ | 1 |
| von Hartitzsch, B | 1 |
| Kjellstrand, CM | 1 |
| Mach, RS | 1 |
| Shirai, D | 1 |
| Kajimoto, Y | 1 |
| Ochi, S | 1 |
| Wada, A | 1 |
| Yano, F | 1 |
| Izumi, M | 1 |
| Fujita, Y | 1 |
| Nakahama, H | 1 |
| Friedl, HP | 1 |
| Till, GO | 1 |
| Trentz, O | 1 |
| Ward, PA | 1 |
| Herchuelz, A | 2 |
| Deger, F | 2 |
| Douchamps, J | 2 |
| Ducarne, H | 2 |
| Broekhuysen, J | 2 |
| Sullivan, FM | 1 |
| Murray, TS | 1 |
| Gaw, N | 1 |
| Langan, JJ | 1 |
| Adams-Strump, BJ | 1 |
| Darlington, LG | 1 |
| Prichard, BN | 1 |
| Brogden, RN | 2 |
| Valentin, B | 1 |
| Laffargue, F | 1 |
| Daures, JP | 1 |
| Hedon, B | 1 |
| Denjean, R | 1 |
| Dujols, P | 1 |
| Loubatières, Y | 1 |
| Viala, JL | 1 |
| Gitsch, E | 1 |
| Berlyne, GM | 1 |
| Shaw, AB | 1 |
| Nilwarangkur, S | 1 |
| Rosenthale, ME | 1 |
| Begany, AJ | 1 |
| Dervinis, A | 1 |
| Malis, JL | 1 |
| Shriver, DA | 1 |
| Datko, SL | 1 |
| Gluckman, MI | 1 |
| Glatt, M | 1 |
| Peskar, B | 1 |
| Brune, K | 1 |
| Denko, CW | 2 |
| Ravera, M | 1 |
| Ugo, C | 1 |
| Caraway, WT | 1 |
| Kramer, HJ | 1 |
| Krück, F | 1 |
| MacFarlane, JP | 1 |
| Kennedy, RD | 1 |
| Leary, WP | 1 |
| Asmal, AC | 1 |
| Seedat, YK | 1 |
| Samuel, P | 1 |
| Dixon, AS | 1 |
| Weber, JC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Webster, ME | 2 |
| Maling, HM | 2 |
| Zweig, MH | 2 |
| Williams, MA | 1 |
| Anderson, W | 1 |
| Presant, CA | 1 |
| Safdar, SH | 1 |
| Smyth, CJ | 1 |
| Percy, JS | 1 |
| Fanelli, O | 1 |
| Trallori, L | 1 |
| Mazzoncini, V | 1 |
| Bianchi, G | 1 |
| Craswell, PW | 1 |
| Ezzat, E | 1 |
| Kopstein, J | 1 |
| Varghese, Z | 1 |
| Moorhead, JF | 1 |
| Leiter, L | 1 |
| Schewitz, LJ | 1 |
| Anderton, JL | 1 |
| Kincaid-Smith, P | 1 |
| Bianchi, C | 1 |
| Bonardi, G | 1 |
| Fitzgerald, TJ | 1 |
| Williams, B | 1 |
| Uyeki, EM | 1 |
| Barbeau, A | 1 |
| Mars, H | 1 |
| Gillo-Joffroy, L | 1 |
| Doliopoulos, T | 1 |
| Liaskou, F | 1 |
| Marousis, S | 1 |
| Shimizu, T | 1 |
| Hiroata, R | 1 |
| Nomura, Y | 1 |
| Aibara, K | 1 |
| Miyaki, K | 1 |
| Laragh, JH | 1 |
| Cannon, PJ | 1 |
| Stason, WB | 1 |
| Heinemann, HO | 1 |
| Whitehouse, MW | 1 |
| Zucchelli, P | 1 |
| Petrella, A | 1 |
| Fusaroli, M | 1 |
| Sasdelli, M | 1 |
| Melica, A | 1 |
| Nash, HL | 1 |
| Fitz, AE | 1 |
| Wilson, WR | 1 |
| Kirkendall, WM | 1 |
| Kioschos, JM | 1 |
| Steigmann, F | 1 |
| Oz, R | 1 |
| Dubin, A | 1 |
| Sölch, G | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Novel Complex Radiodiagnostics of Peripherial Arthropathies[NCT05657847] | 500 participants (Anticipated) | Observational | 2022-03-07 | Recruiting | |||
| Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial[NCT03923933] | Phase 2 | 34 participants (Actual) | Interventional | 2019-06-18 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Change in Diastolic Blood Pressure
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -3.4 |
| Treatment Grup | -13.5 |
Change in Extracellular Water
Decrease in extracellular water measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.15 |
| Treatment Grup | 2.55 |
Change in Extracellular Water / Total Body Water Ratio
Decrease in extracellular water / total body water ratio measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of ECW/TBW (Mean) |
|---|---|
| Placebo | -0.24 |
| Treatment Grup | -2.92 |
Change in Mean Arterial Pressure
decrease in blood pressure compared wit baseline measure (mmhg) (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -5.4 |
| Treatment Grup | -18.1 |
Change in Systolic Blood Pressure
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -10 |
| Treatment Grup | -26.1 |
Change in the Fractional Excretion of Sodium
Increase in the fractional excretion of sodium compared with the baseline measure (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of sodium excreted (Mean) |
|---|---|
| Placebo | -0.348 |
| Treatment Grup | 0.598 |
Change in Total Body Water
Measured by bioelectrical impedance analysis, compared to the initial measurement (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.075 |
| Treatment Grup | -4.36 |
Reviews
7 reviews available for uric acid and Edema
| Article | Year |
|---|---|
Dual-Energy CT for the Musculoskeletal System.
Topics: Adult; Aged; Arthrography; Artifacts; Bone Density; Bone Marrow Diseases; Collagen; Edema; Female; G | 2016 |
Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.
Topics: Animals; Body Weight; Diuretics; Edema; Electrolytes; Half-Life; Humans; Hypertension; Intestinal Ab | 1985 |
[Pharmacological bases of diuretic therapy. 2].
Topics: Acidosis; Alkalosis; Digitalis Glycosides; Diuretics; Drug Synergism; Edema; Gastrointestinal Hemorr | 1974 |
Mefruside: a preliminary report of its pharmacological properties and therapeutic efficacy in oedema and hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Diuresis; Diuretics; Dose-Response Relationship, Drug; Drug Ev | 1974 |
Combinations of diuretics in the treatment of edema.
Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu | 1970 |
Hypertension and renal disease in pregnancy.
Topics: Adrenal Cortex Hormones; Animals; Biopsy; Body Weight; Diet, Sodium-Restricted; Eclampsia; Edema; Fe | 1971 |
Diuretics. II. Clinical considerations.
Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I | 1971 |
Trials
10 trials available for uric acid and Edema
| Article | Year |
|---|---|
Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial.
Topics: Adult; Arthralgia; Arthritis, Gouty; Double-Blind Method; Drugs, Chinese Herbal; Edema; Humans; Medi | 2022 |
Effect of xipamide in oedema of renal disease with varying degrees of renal insufficiency: a comparative trial with frusemide.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Edema; Female; Furosem | 1982 |
Comparative pharmacodynamics of torasemide and furosemide in patients with oedema.
Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Urea Nitrogen; Body Weight; Clinical Trials as Topic; | 1988 |
Is nifedipine a suitable first-line treatment for essential hypertension in general practice?
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1987 |
Torasemide, a new potent diuretic. Double-blind comparison with furosemide.
Topics: Aged; Aged, 80 and over; Body Weight; Clinical Trials as Topic; Creatinine; Diuretics; Double-Blind | 1986 |
[Effect of mefruside on the metabolism of uric acid].
Topics: Clinical Trials as Topic; Diuretics; Edema; Evaluation Studies as Topic; Humans; Metabolic Clearance | 1973 |
The effects of amiloride during diuretic therapy in elderly subjects.
Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinatio | 1972 |
Initial responses of oedematous patients to furosemide and S1520.
Topics: Ankle; Bicarbonates; Blood Glucose; Blood Pressure; Calcium; Chemical Phenomena; Chemistry; Chloride | 1974 |
Xipamid in the treatment of oedema in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Body Weight; Clinical Trials as Topic; Diuretics; Edema; Female; Furose | 1974 |
Physiologic and clincical observations on furosemide and ethacrynic acid.
Topics: Acid-Base Equilibrium; Alkalosis; Chlorides; Clinical Trials as Topic; Diuresis; Edema; Ethacrynic A | 1966 |
Other Studies
82 other studies available for uric acid and Edema
| Article | Year |
|---|---|
Bee Venom Alleviated Edema and Pain in Monosodium Urate Crystals-Induced Gouty Arthritis in Rat by Inhibiting Inflammation.
Topics: Animals; Arthritis, Gouty; Bee Venoms; Disease Models, Animal; Edema; Humans; Inflammation; Male; Pa | 2021 |
Regulation of TRPV1 channel in monosodium urate-induced gouty arthritis in mice.
Topics: Animals; Arthritis, Gouty; Calcium; Edema; Hyperalgesia; Mice; Pain; Transient Receptor Potential Ch | 2022 |
The Protective Effects of Neoastilbin on Monosodium Urate Stimulated THP-1-Derived Macrophages and Gouty Arthritis in Mice through NF-κB and NLRP3 Inflammasome Pathways.
Topics: Animals; Arthritis, Gouty; Edema; Flavonoids; Humans; Inflammasomes; Macrophages; Mice; NF-kappa B; | 2022 |
Anti-Gouty Arthritis and Anti-Hyperuricemia Properties of
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Edema; Hyperuricemia; Interleukin | 2022 |
Excretion of Nitrogenous Waste Products from the Intestinal Fluid Simulator Using Super Absorbent Polymer: A New Generation Dialysis.
Topics: Creatinine; Edema; Electrolytes; Humans; Polymers; Renal Dialysis; Urea; Uric Acid; Waste Products | 2023 |
Articular mobilization promotes improvement in functional and inflammatory parameters in a gouty arthritis model.
Topics: Animals; Arthritis, Gouty; Edema; Humans; Inflammation; Male; Pain; Rats; Rats, Wistar; Uric Acid | 2023 |
Mechanism of DaiTongXiao in the treatment of gouty arthritis through the NLRP3 signaling pathway.
Topics: Adenosine Triphosphate; Animals; Arthritis, Gouty; Caspase 1; Edema; Inflammasomes; Interleukin-6; I | 2024 |
MSU Crystals induce sterile IL-1β secretion via P2X7 receptor activation and HMGB1 release.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Edema; HMGB1 Protein; Humans; Inflammation; | 2020 |
RDP3, A Novel Antigout Peptide Derived from Water Extract of Rice.
Topics: Animals; Anti-Inflammatory Agents; Edema; Gout; Gout Suppressants; Humans; Hyperuricemia; Mice; Mice | 2020 |
Combined effects of MSU crystals injection and high fat-diet feeding on the establishment of a gout model in C57BL/6 mice.
Topics: Animals; Cytokines; Diet, High-Fat; Disease Models, Animal; Edema; Gout; Inflammation; Mice; Mice, I | 2020 |
Discovery of a novel rice-derived peptide with significant anti-gout potency.
Topics: Animals; Edema; Female; Gout; Hyperuricemia; Inflammasomes; Inflammation; Interleukin-1beta; Kidney; | 2020 |
Modified Simiaowan prevents articular cartilage injury in experimental gouty arthritis by negative regulation of STAT3 pathway.
Topics: Animals; Arthritis, Gouty; Cell Line; Chondrocytes; Cytokines; Disease Models, Animal; Drugs, Chines | 2021 |
Simiao Wan attenuates monosodium urate crystal-induced arthritis in rats through contributing to macrophage M2 polarization.
Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arginase; Arthritis, Experimental; Drugs, C | 2021 |
Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Chromatography, High Pressure Liquid; Disease M | 2017 |
Effects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice.
Topics: Animals; Arthritis, Experimental; Arthritis, Gouty; Behavior, Animal; Cytokines; Edema; Foot; Male; | 2017 |
Luteolin-4'-O-glucoside and its aglycone, two major flavones of Gnaphalium affine D. Don, resist hyperuricemia and acute gouty arthritis activity in animal models.
Topics: Animals; Arthritis, Gouty; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Glucose Transport P | 2018 |
Protective effects of Rhizoma smilacis glabrae extracts on potassium oxonate- and monosodium urate-induced hyperuricemia and gout in mice.
Topics: Animals; Antioxidants; Arthritis, Gouty; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Flavo | 2019 |
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
Topics: Anacardiaceae; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Chalcone; Dose-Re | 2019 |
Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation.
Topics: Adult; Animals; Body Fluids; Cytokines; Disease Models, Animal; Down-Regulation; Edema; Female; Foot | 2019 |
Anti-inflammatory and antinociceptive effects of Chinese medicine SQ gout capsules and its modulation of pro-inflammatory cytokines focusing on gout arthritis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Capsules; Cells, Cultu | 2013 |
Suppressive effect of modified Simiaowan on experimental gouty arthritis: an in vivo and in vitro study.
Topics: Acetic Acid; Analgesics; Animals; Ankle Joint; Anti-Inflammatory Agents; Arthritis, Gouty; Cell Surv | 2013 |
The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin B1 Receptor Antagonists | 2016 |
Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model.
Topics: Animals; Ankle; Ankle Joint; Anthozoa; Anti-Inflammatory Agents; Arthritis, Gouty; Biological Produc | 2015 |
Targeting inflammatory mediators with ferulic acid, a dietary polyphenol, for the suppression of monosodium urate crystal-induced inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Coumaric Acids; Drug Delivery Systems; Edema; F | 2016 |
Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Biomarkers; Cytokines; Disease Mo | 2016 |
Efficacy of CoenzymeQ10 in inhibiting monosodium urate crystal-induced inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Edema; Female; Inflammation; Lipid Peroxidation | 2016 |
6-Shogaol inhibits monosodium urate crystal-induced inflammation--an in vivo and in vitro study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechols; Crystallization; Dose-Res | 2010 |
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.
Topics: Acrylamides; Anilides; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antioxidants; Bridged B | 2011 |
Therapeutic properties of quercetin on monosodium urate crystal-induced inflammation in rat.
Topics: Animals; Ankle Joint; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Chemokines; Disease | 2012 |
The antinociceptive and anti-inflammatory effects of the crude extract of Jatropha isabellei in a rat gout model.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Biomarkers, Pharmacological; Disease | 2013 |
Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents; Arthritis, Gouty; Colchicine; Cyclooxygenase 2; Edema; | 2013 |
[EXPERIMENTAL HYPERURICEMIA. RESEARCH ON RABBITS. (ALLANTOIN AND URIC ACID)].
Topics: Allantoin; Animals; Anuria; Blood; Edema; Hydantoins; Hyperuricemia; Kidney Tubules; Lagomorpha; Pat | 1963 |
UREMIC TOXICITY CORRELATED WITH UNIDENTIFIED ANIONS.
Topics: Anions; Blood Chemical Analysis; Creatine; Creatinine; Edema; Glomerulonephritis; Ileostomy; Kidney; | 1963 |
USE OF BENDROFLUMETHIAZIDE WITH POTASSIUM SUPPLEMENT IN TOXEMIA OF PREGNANCY.
Topics: Bendroflumethiazide; Blood; Blood Pressure; Drug Therapy; Eclampsia; Edema; Female; Fetal Death; Hum | 1965 |
CLINICAL EXPERIENCE WITH A NEW DIURETIC, FUROSEMIDE.
Topics: Diabetes Mellitus; Diuretics; Edema; Furosemide; Geriatrics; Humans; Potassium; Uric Acid | 1965 |
Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis.
Topics: Animals; Arthritis, Experimental; Chemotaxis; Chemotaxis, Leukocyte; Disease Models, Animal; Down-Re | 2006 |
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
Topics: Aged; Creatinine; Diagnosis, Differential; Diuretics; Edema; Female; Humans; Hyponatremia; Hypovolem | 2007 |
The endogenous danger signal uric Acid augments contact hypersensitivity responses in mice.
Topics: Animals; B7-2 Antigen; CD40 Antigens; Chlorobenzenes; Dendritic Cells; Dermatitis, Contact; Drug Syn | 2007 |
Experimental investigation and observations on the diuretic action of quinethazone.
Topics: Acetazolamide; Adult; Chlorides; Chlorothiazide; Creatine; Diuresis; Drug Synergism; Edema; Female; | 1966 |
[Experiences with ethacrynic acid, a new diuretic].
Topics: Creatine; Edema; Ethacrynic Acid; Glycosuria; Heart Failure; Humans; Liver Function Tests; Myocardia | 1966 |
[Clinical observations with the new saluretic 2,3-dichlor-4-(2-methylene-butryl-phenoxy-acetic acid (ethacrynic acid)].
Topics: Adult; Blood Pressure Determination; Chlorine; Diuretics; Edema; Ethacrynic Acid; Humans; Male; Midd | 1966 |
Clinical trial of a potassium-sparing saluretic pyrazine derivative (MK-870).
Topics: Adult; Aged; Carbon Dioxide; Chlorides; Creatine; Diuretics; Edema; Female; Heart Failure; Humans; L | 1967 |
Suppressive effects of indomethacin on crystal-induced inflammation in canine joints and on neutrophilic motility in vitro.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis; Blood Flow Velocity; Blood Pressure; Do | 1967 |
Experimentally induced inflammation of the guinea pig palatal mucosa by injection of a microcrystalline suspension of monosodium urate.
Topics: Animals; Collagen; Edema; Fibroblasts; Guinea Pigs; Lymphocytes; Male; Monocytes; Mouth Mucosa; Neut | 1984 |
Inflammation in the rat paw due to urate crystals. Involvement of the kinin system.
Topics: Animals; Edema; Inflammation; Kinins; Leukocytes; Male; Rats; Rats, Inbred Strains; Time Factors; Ur | 1984 |
Adjuvant polyarthritis. VI. Effect of oxonate-induced hyperuricemia on the development of acute inflammation, immune response and adjuvant arthritis.
Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Cell Line; Diet; Edema; Immunity, C | 1981 |
A case of familial renal hypouricemia associated with increased secretion of para-aminohippurate and idiopathic edema.
Topics: Adult; Aged; Aminohippuric Acids; Edema; Female; Humans; Kidney Function Tests; Male; p-Aminohippuri | 1982 |
Inhibitory action of indomethacin on neutrophil infiltration in monosodium urate-induced pleurisy in rats.
Topics: Administration, Oral; Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; | 1995 |
[Twin pregnancy and preeclampsia].
Topics: Adult; Biomarkers; Comorbidity; Edema; Female; Gravidity; Humans; Hypertension; Incidence; Parity; P | 2000 |
[Pharmacological studies on carprofen, a new non-steroidal anti-inflammatory drug, in animals (author's transl)].
Topics: Adrenal Cortex; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents | 1977 |
The kidney and pregnancy.
Topics: Blood Pressure; Blood Urea Nitrogen; Body Weight; Eclampsia; Edema; Female; Glomerular Filtration Ra | 1978 |
Pathoanatomical features of the kidney in myelomonocytic and chronic lymphocytic leukemia.
Topics: Acute Kidney Injury; Adult; Aged; Edema; Female; Humans; Kidney; Kidney Glomerulus; Kidney Tubules; | 1975 |
Diuretics in malignant effusions and edemas of generalized cancer.
Topics: Ascites; Body Weight; Bumetanide; Diuretics; Drinking; Edema; Furosemide; Humans; Neoplasms; Pleuris | 1976 |
Prolactin in hypertensive pregnancy.
Topics: Edema; Female; Humans; Hypertension; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, | 1975 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote | 1975 |
[Editorial: Edema from diuretics abuse].
Topics: Adult; Diuretics; Edema; Female; Humans; Hyperaldosteronism; Hyperglycemia; Hypokalemia; Hyponatremi | 1976 |
Evaluation of hemodialysis efficiency by an edema fluid model.
Topics: Adult; Aged; Creatinine; Edema; Extracellular Space; Humans; Kidney Failure, Chronic; Middle Aged; R | 1992 |
Roles of histamine, complement and xanthine oxidase in thermal injury of skin.
Topics: Animals; Burns; Cimetidine; Complement Inactivator Proteins; Complement System Proteins; Cromolyn So | 1989 |
Study to compare the relative hyperuricaemic effects of frusemide and bumetanide.
Topics: Aged; Bumetanide; Diuretics; Edema; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; M | 1986 |
[Evaluation of the clinical and biologic means of assessing fetal prognosis in pregnancy toxemias. Apropos of 223 cases].
Topics: Blood Coagulation Disorders; Blood Pressure; Body Weight; Circadian Rhythm; Edema; Female; Fetal Dis | 1985 |
[Early diagnosis, prevention and basic pathology of EPH gestosis].
Topics: Brain Edema; Diet, Sodium-Restricted; Edema; Energy Intake; Female; Humans; Hypertension; Pre-Eclamp | 1985 |
Dietary treatment of chronic renal failure. Experiences with a modified Giovannetti diet.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Aged; Arteritis; Dietary Proteins; Edema; Female; | 1965 |
Anti-inflammatory properties of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin).
Topics: Airway Obstruction; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; B | 1974 |
Leukocytes and prostaglandins in acute inflammation.
Topics: Acute Disease; Animals; Arthritis; Blood Platelets; Capillary Permeability; Cell Movement; Cell-Free | 1974 |
A phlogistic function of prostaglandin E1 in urate crystal inflammation.
Topics: Animals; Crystallization; Edema; Fatty Acids, Essential; Hindlimb; Hot Temperature; Inflammation; Ma | 1974 |
The scientific development of clinical chemistry to 1948.
Topics: Albuminuria; Animals; Biochemistry; Blood; Blood Glucose; Chemistry, Clinical; Colorimetry; Edema; E | 1973 |
Urate crystal induced inflammation in the rat: evidence for the combined actions of kinins, histamine and components of complement.
Topics: Animals; Carboxypeptidases; Colchicine; Complement System Proteins; Cyproheptadine; Edema; Female; G | 1972 |
Oxymetholone in myelofibrosis and chronic lymphocytic leukemia.
Topics: Aged; Anemia, Aplastic; Blood Cell Count; Blood Platelets; Blood Transfusion; Chemical and Drug Indu | 1973 |
Comparison of indomethacin and phenylbutazone in acute gout.
Topics: Acute Disease; Adult; Aged; Blood Sedimentation; Edema; Female; Gout; Humans; Indomethacin; Leukocyt | 1973 |
[Anti-inflammatory effect of 2-phenyl-5-bromo-indandione (Uridion) with uricosuric acitivity].
Topics: Animals; Anti-Inflammatory Agents; Bromine; Drug Evaluation; Edema; Female; Indenes; Indomethacin; M | 1973 |
Use of metolazone, a new diuretic, in patients with renal disease.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Creatinine; Diu | 1974 |
Inhibition of sodium urate-induced rat hindpaw edema by colchicine derivatives: correlation with antimitotic activity.
Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Division; Colchicine; Edema; Female; Hindlimb; Male; | 1972 |
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. General pharmacological properties.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Blood Glucose; Cardiovascular System; | 1972 |
Effects of antimitotic and anti-inflammatory agents on sodium urate-induced paw swelling in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Colchicine; Edema; Female; Foot; Hindlimb; | 1971 |
Adverse clinical side effects of levodopa therapy.
Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede | 1971 |
Comparison of the action of two new oral diuretics, the 4-chloro-N-methyl-3-(methylsulfamoly) benzamide and 4-chloro-3-sulfamylbenzoic acid 2,2-dimethylhydrazide (a study on 102 patients).
Topics: Adult; Aged; Arteries; Blood Glucose; Blood Pressure; Body Weight; Diuretics; Edema; Heart Failure; | 1968 |
Nephrotoxic effect of MSG (monosodium glutamate) in the chicken.
Topics: Acute Kidney Injury; Animals; Atrophy; Body Weight; Chickens; Edema; Extremities; Gallbladder; Gluta | 1971 |
Effects of colchicine in rats with urate crystal-induced inflammation.
Topics: Adrenal Glands; Animals; Body Weight; Colchicine; Crystallization; Edema; Gout; Inflammation; Male; | 1970 |
[Ethacrynic acid: research on the mechanism of action and clinical use].
Topics: Adolescent; Adult; Aged; Child; Diabetes Insipidus; Diuresis; Edema; Ethacrynic Acid; Female; Heart | 1968 |
Cardiorenal hemodynamic effects of ethacrynic acid.
Topics: Chlorothiazide; Diabetes Insipidus; Edema; Electrolytes; Ethacrynic Acid; Heart; Heart Failure; Hear | 1966 |
Newer diuretics in the treatment of cardiac or hepatic disease in elderly patients.
Topics: Ascites; Benzothiadiazines; Blood Glucose; Blood Urea Nitrogen; Body Weight; Cardiovascular Diseases | 1966 |
[Polythiazide and chlorthalidone in pregnancy edema].
Topics: Blood Glucose; Blood Pressure; Chlorine; Chlorthalidone; Diuresis; Edema; Female; Humans; Polythiazi | 1966 |