Page last updated: 2024-10-20

uric acid and E coli Infections

uric acid has been researched along with E coli Infections in 9 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Uric acid crystals were formed in vivo in the lumen of the gut in response to EPEC and STEC infections."1.43Biological Activities of Uric Acid in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli. ( Broome, JE; Crane, JK; Lis, A, 2016)
" In Experiment 1, vitamin D3 was supplemented at a dosage of either 2,064 IU/kg (low level) or 4,128 IU/kg (high level) in drinking water provided ad libitum only from Days 1 through 5 after hatch."1.31The effect of vitamin D3 on resistance to stress-related infection in an experimental model of turkey osteomyelitis complex. ( Balog, JM; Huff, GR; Huff, WE; Rath, NC, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Balestracci, A2
Meni Battaglia, L2
Toledo, I2
Beaudoin, L1
Martin, SM2
Grisolía, NA1
Hogg, RJ1
Crane, JK2
Broome, JE2
Lis, A1
Lu, B1
Nakamura, T1
Inouye, K1
Li, J1
Tang, Y1
Lundbäck, P1
Valdes-Ferrer, SI1
Olofsson, PS1
Kalb, T1
Roth, J1
Zou, Y1
Erlandsson-Harris, H1
Yang, H1
Ting, JP1
Wang, H1
Andersson, U1
Antoine, DJ1
Chavan, SS1
Hotamisligil, GS1
Tracey, KJ1
Naeher, TM1
Boedeker, EC1
Friesen, A1
Stern, J1
Hofstetter, AG1
Schilling, A1
Huff, GR1
Huff, WE1
Balog, JM1
Rath, NC1
Gellman, AC1
Malament, M1
Notelovitz, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC): A Phase II Clinical Study[NCT01984892]Phase 28 participants (Actual)Interventional2013-11-30Terminated (stopped due to PI discretion, low enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival in Treated Patients

Patients who are alive on the date of closing follow-up, or 30 months after completing all study treatments, will be censored on that date (NCT01984892)
Timeframe: up to 30 months

InterventionParticipants (Count of Participants)
Participants With Stage 4 Cancer8

Progression-free Survival

"Progression-free survival defined as the time in weeks from study entry until tumor progression defined using the Wolchok criteria or death. Patients who are alive and free from progression on the date of closing follow-up will be censored on that date.~In order to minimize the potential for misdiagnosis of pseudoprogression, related to early inflammation, tumor measurement for determination of progression will be made at the earliest at 26 weeks." (NCT01984892)
Timeframe: average 52 weeks

Interventionweeks (Number)
Participants With Stage 4 Cancer41

Other Studies

9 other studies available for uric acid and E coli Infections

ArticleYear
Hyperuricemia: an unrecognized risk factor for kidney-related sequelae in children with hemolytic uremic syndrome.
    Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:5

    Topics: Case-Control Studies; Child; Disease Progression; Escherichia coli Infections; Hemolytic-Uremic Synd

2023
Rasburicase in hemolytic uremic syndrome related to Shiga toxin-producing Escherichia coli: a report of nine cases.
    Pediatric nephrology (Berlin, Germany), 2020, Volume: 35, Issue:6

    Topics: Child, Preschool; Dialysis; Escherichia coli Infections; Female; Hemolytic-Uremic Syndrome; Humans;

2020
Biological Activities of Uric Acid in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli.
    Infection and immunity, 2016, Volume: 84, Issue:4

    Topics: Animals; Cell Line; Colforsin; Enterohemorrhagic Escherichia coli; Escherichia coli Infections; Gast

2016
Novel role of PKR in inflammasome activation and HMGB1 release.
    Nature, 2012, Aug-30, Volume: 488, Issue:7413

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Animals; Antigens, Bacterial; Apoptosi

2012
Role of host xanthine oxidase in infection due to enteropathogenic and Shiga-toxigenic Escherichia coli.
    Infection and immunity, 2013, Volume: 81, Issue:4

    Topics: Animals; Bodily Secretions; Cell Line; Disease Models, Animal; Enteropathogenic Escherichia coli; Es

2013
[Nephrolithiasis--correlation of calculus type and pathogen spectrum. Calculus analysis and microbiologic diagnosis in 173 surgically treated patients].
    Fortschritte der Medizin, 1984, Nov-22, Volume: 102, Issue:43

    Topics: Bacteriological Techniques; Calcium Oxalate; Escherichia coli Infections; Female; Humans; Kidney Cal

1984
The effect of vitamin D3 on resistance to stress-related infection in an experimental model of turkey osteomyelitis complex.
    Poultry science, 2000, Volume: 79, Issue:5

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Bod

2000
Partial nephrectomy in renal calculus disease.
    Urology, 1973, Volume: 1, Issue:4

    Topics: Adult; Aged; Dilatation; Escherichia coli Infections; Follow-Up Studies; Humans; Kidney; Kidney Calc

1973
The pregnant Natal Indian diabetic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Apr-05, Volume: 43, Issue:14

    Topics: Adolescent; Adrenal Glands; Adult; Blood Glucose; Body Height; Body Weight; Cholesterol; Escherichia

1969