uric acid has been researched along with Diffuse Large B-Cell Lymphoma in 12 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "15 mg/kg) administered as single dose followed by as needed dosing (maximum five doses) versus daily dosing for 5 days in adult patients at risk for TLS." | 2.77 | A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome. ( Bueso-Ramos, CE; Cortes, JE; Fanale, MA; Fayad, LE; Fowler, N; Hagemeister, FB; Kwak, LW; McLaughlin, PW; Orlowski, RZ; Pro, B; Rodriguez, A; Romaguera, JE; Samaniego, F; Sarlis, NJ; Shah, J; Vadhan-Raj, S; Wang, M; Younes, A; Zhou, X, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ariga, Y | 1 |
| Low, S | 1 |
| Hoshino, H | 1 |
| Nakada, T | 1 |
| Akama, TO | 1 |
| Muramoto, A | 1 |
| Fukushima, M | 1 |
| Yamauchi, T | 1 |
| Ohshima, Y | 1 |
| Kobayashi, M | 1 |
| Prochazka, KT | 1 |
| Melchardt, T | 1 |
| Posch, F | 1 |
| Schlick, K | 1 |
| Deutsch, A | 1 |
| Beham-Schmid, C | 1 |
| Weiss, L | 1 |
| Gary, T | 1 |
| Neureiter, D | 1 |
| Klieser, E | 1 |
| Greil, R | 1 |
| Neumeister, P | 1 |
| Egle, A | 1 |
| Pichler, M | 1 |
| Fricker, J | 1 |
| Vadhan-Raj, S | 1 |
| Fayad, LE | 1 |
| Fanale, MA | 1 |
| Pro, B | 1 |
| Rodriguez, A | 1 |
| Hagemeister, FB | 1 |
| Bueso-Ramos, CE | 1 |
| Zhou, X | 1 |
| McLaughlin, PW | 1 |
| Fowler, N | 1 |
| Shah, J | 1 |
| Orlowski, RZ | 1 |
| Samaniego, F | 1 |
| Wang, M | 1 |
| Cortes, JE | 1 |
| Younes, A | 1 |
| Kwak, LW | 1 |
| Sarlis, NJ | 1 |
| Romaguera, JE | 1 |
| Chiang, J | 1 |
| Chan, A | 1 |
| Lian, T | 1 |
| Tay, K | 1 |
| Quek, R | 1 |
| Tao, M | 1 |
| Lim, ST | 1 |
| KRAKOFF, IH | 1 |
| MEYER, RL | 1 |
| Weisel, KC | 1 |
| Brugger, W | 1 |
| Kröber, SM | 1 |
| Kaiserling, E | 1 |
| Kanz, L | 1 |
| Roy-Chaudhury, P | 1 |
| Kizer, N | 1 |
| Martinez, E | 1 |
| Powell, M | 1 |
| Hande, KR | 1 |
| Garrow, GC | 1 |
| Poddubnaia, IV | 1 |
| Mansurov, AN | 1 |
| Fominykh, VG | 1 |
| Treske, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Study of Rasburicase Administered by Two Different Schedules (Fixed Dosing vs. As Needed Dosing) in Patients at High Risk or Potential Risk for Tumor Lysis Syndrome[NCT00628628] | Phase 2 | 82 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Plasma UA response is defined as normalization of plasma UA levels within 48 hours after the start of study drug (rasburicase) and maintaining within the normal range after the final drug infusion on day 5. Plasma samples for UA were collected at baseline before rasburicase, 4- and 24-hours post-rasburicase, and daily during treatment. (NCT00628628)
Timeframe: First cycle of chemotherapy, up to 5 days
| Intervention | participants (Number) |
|---|---|
| Group A: Single Dose | 39 |
| Group B: Daily Dose | 34 |
2 reviews available for uric acid and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
Management of tumor lysis syndrome with a single fixed dose of rasburicase in Asian lymphoma patients: a case series and literature review.
Topics: Adult; Aged; Aged, 80 and over; Asia; Burkitt Lymphoma; Creatinine; Female; Humans; L-Lactate Dehydr | 2011 |
Acute tumor lysis syndrome in patients with high-grade non-Hodgkin's lymphoma.
Topics: Acute Disease; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Blood Urea Nitrogen; Bur | 1993 |
1 trial available for uric acid and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Gout Suppressants; Humans; Lymphoma, | 2012 |
9 other studies available for uric acid and Diffuse Large B-Cell Lymphoma
| Article | Year |
|---|---|
Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia.
Topics: B-Lymphocytes; Burkitt Lymphoma; Humans; Lymphoma, Large B-Cell, Diffuse; Precursor Cell Lymphoblast | 2022 |
NCCN-IPI score-independent prognostic potential of pretreatment uric acid levels for clinical outcome of diffuse large B-cell lymphoma patients.
Topics: Adult; Aged; Antineoplastic Agents; Austria; Biomarkers, Tumor; Disease-Free Survival; Female; Human | 2016 |
50th ASH Annual Meeting.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Humans; Lenalidomide; Leukemia, Lymp | 2009 |
PREVENTION OF HYPERURICEMIA IN LEUKEMIA AND LYMPHOMA: USE OF ALOPURINOL, A XANTHINE OXIDASE INHIBITOR.
Topics: Adolescent; Antineoplastic Agents; Blood; Blood Urea Nitrogen; Drug Therapy; Geriatrics; Humans; Hyp | 1965 |
Intravascular lymphoma - a rare cause of hemolytic anemia and neurologic disorders.
Topics: Aged; Anemia, Hemolytic; Biomarkers, Tumor; Diagnosis, Differential; Disease Progression; Fatal Outc | 2004 |
Spontaneous self-alkalinization in spontaneous tumor lysis syndrome.
Topics: Humans; Hydrogen-Ion Concentration; Kidney Calculi; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffus | 2006 |
Report of two cases of rasburicase-induced methemoglobinemia.
Topics: Acquired Immunodeficiency Syndrome; Humans; Hyperuricemia; Lymphoma, AIDS-Related; Lymphoma, Large B | 2006 |
[Use of milurit in hyperuricemia in patients with malignant hemopathies].
Topics: Adolescent; Adult; Aged; Allopurinol; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma; | 1975 |
[Indomethacin in hemoblastosis].
Topics: Hodgkin Disease; Humans; Indomethacin; Joint Diseases; Leukemia; Lymphoma; Lymphoma, Large B-Cell, D | 1971 |