Page last updated: 2024-10-20

uric acid and Diabetic Retinopathy

uric acid has been researched along with Diabetic Retinopathy in 43 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"To determine the association of uric acid (UA) and glucose in aqueous humor with diabetic macular edema (DME) in patients with Type 2 diabetes."8.12ELEVATED LEVEL OF URIC ACID, BUT NOT GLUCOSE, IN AQUEOUS HUMOR AS A RISK FACTOR FOR DIABETIC MACULAR EDEMA IN PATIENTS WITH TYPE 2 DIABETES. ( Chan, SO; He, BT; Qin, YJ; Wang, S; Yu, HH; Zhang, HY; Zhang, YL; Zhang, YQ, 2022)
"To investigate the role of serum uric acid and leukocyte counts and ratios as predictors of clinical outcomes of intravitreal bevacizumab in diabetic macular edema."8.12Association of White Blood Cell Counts, Leukocyte Ratios, and Serum Uric Acid with Clinical Outcome of Intravitreal Bevacizumab in Diabetic Macular Edema. ( Arabi, A; Karimi, S; Safi, S; Shahraki, T, 2022)
"To investigate the association between serum uric acid (SUA) levels and vision-threatening diabetic retinopathy (VTDR) in patients with type 2 diabetes."8.02Higher Serum Uric Acid Levels Are Associated With an Increased Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes Patients. ( Chan, Z; Chen, H; Gu, C; Hu, Y; Li, C; She, X; Shi, Y; Wang, Y; Zhao, S; Zheng, Z; Zhou, C, 2021)
"This study aims to investigate the relationship between serum uric acid (SUA) and the severity of diabetic nephropathy (DN) and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM)."7.96Serum uric acid is independently associated with diabetic nephropathy but not diabetic retinopathy in patients with type 2 diabetes mellitus. ( Hu, AP; Li, DM; Su, S; Xia, Q; Yang, SM; Zhang, SH; Zhu, J; Zhu, XL, 2020)
"To analyze the associations of serum uric acid (SUA) level with diabetic microvascular complications, including diabetic retinopathy (DR) and diabetic nephropathy (DN), in patients with type 2 diabetes mellitus (DM)."7.96Associations of serum uric acid level with diabetic retinopathy and albuminuria in patients with type 2 diabetes mellitus. ( Chen, Q; Hou, L; Li, Q; Shi, Y; Wang, S; Zhao, M; Zhou, X, 2020)
"Uric acid has been proposed as an independent risk factor of diabetic retinopathy."7.88The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway. ( She, XP; Wang, YZ; Zheng, Z; Zhu, DD; Zou, C, 2018)
"We assessed the prospective association between baseline serum uric acid levels and consequent risk of developing diabetic retinopathy."7.85Serum uric acid levels are associated with increased risk of newly developed diabetic retinopathy among Japanese male patients with type 2 diabetes: A prospective cohort study (diabetes distress and care registry at Tenri [DDCRT 13]). ( Hayashino, Y; Ishii, H; Kuwata, H; Okamura, S; Tsujii, S, 2017)
"To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes."7.81Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015)
"To explore the role of serum uric acid (SUA) concentration in diabetic retinopathy (DR) for patients with type 2 diabetes mellitus (T2DM)."7.80Serum uric acid concentration is associated with worsening in severity of diabetic retinopathy among type 2 diabetic patients in Taiwan--a 3-year prospective study. ( Chen, CH; Chen, YJ; Chung, MS; Kuo, HK; Lee, JJ; Liu, RT; Yang, IH, 2014)
" Lipid profiles, ACR, bilirubin, uric acid, creatine kinase, and hsCRP were not changed in DM patients with different diabetic duration or diabetic retinopathy."7.73Homocysteine and other biochemical parameters in Type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy. ( Chang, MH; Chen, TH; Chen, YJ; Hsu, HH; Huang, CY; Huang, EJ; Kuo, WW; Lee, SD; Lu, MC; Tzang, BS, 2006)
"A total of 518 individuals with type 2 diabetes were included."5.56Associations of serum uric acid and urinary albumin with the severity of diabetic retinopathy in individuals with type 2 diabetes. ( Chen, D; Liu, Y; Sun, X; Zhao, X, 2020)
"Patients with type 2 diabetes mellitus (DM) may experience chronic microvascular complications such as diabetic retinopathy (DR) and diabetic nephropathy (DN) during their lifetime."5.43Association of Serum Uric Acid Concentration with Diabetic Retinopathy and Albuminuria in Taiwanese Patients with Type 2 Diabetes Mellitus. ( Chen, SC; Hsiao, PJ; Hsu, WH; Lee, MY; Liang, CC; Lin, KD; Lin, PC; Shin, SJ, 2016)
"To determine the association of uric acid (UA) and glucose in aqueous humor with diabetic macular edema (DME) in patients with Type 2 diabetes."4.12ELEVATED LEVEL OF URIC ACID, BUT NOT GLUCOSE, IN AQUEOUS HUMOR AS A RISK FACTOR FOR DIABETIC MACULAR EDEMA IN PATIENTS WITH TYPE 2 DIABETES. ( Chan, SO; He, BT; Qin, YJ; Wang, S; Yu, HH; Zhang, HY; Zhang, YL; Zhang, YQ, 2022)
"To investigate the role of serum uric acid and leukocyte counts and ratios as predictors of clinical outcomes of intravitreal bevacizumab in diabetic macular edema."4.12Association of White Blood Cell Counts, Leukocyte Ratios, and Serum Uric Acid with Clinical Outcome of Intravitreal Bevacizumab in Diabetic Macular Edema. ( Arabi, A; Karimi, S; Safi, S; Shahraki, T, 2022)
"To investigate the association between serum uric acid (SUA) levels and vision-threatening diabetic retinopathy (VTDR) in patients with type 2 diabetes."4.02Higher Serum Uric Acid Levels Are Associated With an Increased Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes Patients. ( Chan, Z; Chen, H; Gu, C; Hu, Y; Li, C; She, X; Shi, Y; Wang, Y; Zhao, S; Zheng, Z; Zhou, C, 2021)
"This study aims to investigate the relationship between serum uric acid (SUA) and the severity of diabetic nephropathy (DN) and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM)."3.96Serum uric acid is independently associated with diabetic nephropathy but not diabetic retinopathy in patients with type 2 diabetes mellitus. ( Hu, AP; Li, DM; Su, S; Xia, Q; Yang, SM; Zhang, SH; Zhu, J; Zhu, XL, 2020)
"To analyze the associations of serum uric acid (SUA) level with diabetic microvascular complications, including diabetic retinopathy (DR) and diabetic nephropathy (DN), in patients with type 2 diabetes mellitus (DM)."3.96Associations of serum uric acid level with diabetic retinopathy and albuminuria in patients with type 2 diabetes mellitus. ( Chen, Q; Hou, L; Li, Q; Shi, Y; Wang, S; Zhao, M; Zhou, X, 2020)
"Uric acid has been proposed as an independent risk factor of diabetic retinopathy."3.88The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway. ( She, XP; Wang, YZ; Zheng, Z; Zhu, DD; Zou, C, 2018)
"We assessed the prospective association between baseline serum uric acid levels and consequent risk of developing diabetic retinopathy."3.85Serum uric acid levels are associated with increased risk of newly developed diabetic retinopathy among Japanese male patients with type 2 diabetes: A prospective cohort study (diabetes distress and care registry at Tenri [DDCRT 13]). ( Hayashino, Y; Ishii, H; Kuwata, H; Okamura, S; Tsujii, S, 2017)
"To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes."3.81Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015)
"To explore the role of serum uric acid (SUA) concentration in diabetic retinopathy (DR) for patients with type 2 diabetes mellitus (T2DM)."3.80Serum uric acid concentration is associated with worsening in severity of diabetic retinopathy among type 2 diabetic patients in Taiwan--a 3-year prospective study. ( Chen, CH; Chen, YJ; Chung, MS; Kuo, HK; Lee, JJ; Liu, RT; Yang, IH, 2014)
"Over a 20-year period, patients on dapagliflozin were projected to experience relative reductions in the incidence of myocardial infarction (MI), stroke, CV death, and all-cause death of 13."3.80Modeling effects of SGLT-2 inhibitor dapagliflozin treatment versus standard diabetes therapy on cardiovascular and microvascular outcomes. ( Alperin, P; Cohen, M; Dziuba, J; Goswami, D; Grossman, HL; Hardy, E; Iloeje, U; Perlstein, I; Racketa, J, 2014)
"Plasma levels for fasting glucose, glycosylated hemoglobin, ceruloplasmin and serum concentrations for fructosamine and uric acid were significantly increased in diabetic foot patients vs."3.74Diabetic foot patients with and without retinopathy and plasma oxidative stress. ( Coman, A; Găman, L; Greabu, M; Gruia, V; Mohora, M; Muscurel, C; Vîrgolici, B, 2007)
" Lipid profiles, ACR, bilirubin, uric acid, creatine kinase, and hsCRP were not changed in DM patients with different diabetic duration or diabetic retinopathy."3.73Homocysteine and other biochemical parameters in Type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy. ( Chang, MH; Chen, TH; Chen, YJ; Hsu, HH; Huang, CY; Huang, EJ; Kuo, WW; Lee, SD; Lu, MC; Tzang, BS, 2006)
" Patients within the lowest C-peptide quartile showed significantly higher duration of diabetes, prevalence of retinopathy and values of HDL-cholesterol, albumin excretion rate and HbA1c, while BMI, diastolic blood pressure, percentages of hypertension and metabolic syndrome, and values of triglycerides and uric acid were significantly higher in the highest C-peptide quartile."3.70Relationship of residual beta-cell function, metabolic control and chronic complications in type 2 diabetes mellitus. ( Bo, S; Cavallo-Perin, P; Gentile, L; Pagano, G; Repetti, E, 2000)
" In 2 cases a mild diabetes mellitus, in 7 cases uric acid level in serum was raised."3.65[Clinical-neurological and electromyographical studies of inpatients isolated with selective pigmentary retinopathy]. ( Eickhoff, W; Hellner, KA; Müller-Jensen, A, 1975)
"Patients with type 2 diabetes mellitus hospitalized over the period between January 2010 and September 2018 were retrospectively collected."1.72Using Machine Learning Techniques to Develop Risk Prediction Models for the Risk of Incident Diabetic Retinopathy Among Patients With Type 2 Diabetes Mellitus: A Cohort Study. ( Chen, W; Dong, M; Gao, Z; Li, P; Li, S; Li, X; Liu, X; Yu, H; Yu, Q; Zhang, M; Zhao, Y, 2022)
"299 patients with type 2 diabetes mellitus (T2DM) hospitalized in the Second Affiliated Hospital of Soochow University were enrolled."1.72Genomic DNA Methylation in Diabetic Chronic Complications in Patients With Type 2 Diabetes Mellitus. ( Hu, J; Jiang, M; Wang, X; Yang, W; Zhang, HH; Zhang, S; Zhu, Y, 2022)
"A total of 518 individuals with type 2 diabetes were included."1.56Associations of serum uric acid and urinary albumin with the severity of diabetic retinopathy in individuals with type 2 diabetes. ( Chen, D; Liu, Y; Sun, X; Zhao, X, 2020)
"Median time to recurrence was 64 months."1.56Predictive Factors for Kidney Stone Recurrence in Type 2 Diabetes Mellitus. ( Monga, M; Prasanchaimontri, P, 2020)
"Uric acid is a final breakdown product of purine catabolism in humans."1.46Correlation of retinal nerve fibre layer and macular thickness with serum uric acid among type 2 diabetes mellitus. ( Azreen-Redzal, A; Nyi-Nyi, N; Vinuthinee-Naidu, MN; Zunaina, E, 2017)
"Patients with type 2 diabetes mellitus (DM) may experience chronic microvascular complications such as diabetic retinopathy (DR) and diabetic nephropathy (DN) during their lifetime."1.43Association of Serum Uric Acid Concentration with Diabetic Retinopathy and Albuminuria in Taiwanese Patients with Type 2 Diabetes Mellitus. ( Chen, SC; Hsiao, PJ; Hsu, WH; Lee, MY; Liang, CC; Lin, KD; Lin, PC; Shin, SJ, 2016)
"By analysing factors associated with diabetic nephropathy rather than microvascular disease in general, this study provides evidence that night-time diastolic BP and a relative increase in platelet count are associated with incipient diabetic nephropathy."1.38Factors associated with diabetic nephropathy in subjects with proliferative retinopathy. ( Buhagiar, G; Calleja, N; Fava, S; Magri, CJ; Vassallo, J, 2012)
"A total of 102 type 2 diabetes mellitus patients were divided into 2 groups: DR group (age, 60 +/- 6 years [mean +/- SD]; n = 31) and no diabetic retinopathy (NDR) group (59 +/- 5 years, n = 71)."1.36Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients. ( Anan, F; Eshima, N; Eto, T; Ito, Y; Masaki, T; Saikawa, T; Umeno, Y; Yoshimatsu, H, 2010)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19908 (18.60)18.7374
1990's5 (11.63)18.2507
2000's3 (6.98)29.6817
2010's15 (34.88)24.3611
2020's12 (27.91)2.80

Authors

AuthorsStudies
Sun, W1
Shi, Y3
Yang, J1
Song, X1
Zhang, Y1
Zhang, W1
Zhou, X2
Qin, YJ1
Zhang, YL1
Zhang, YQ1
He, BT1
Wang, S2
Yu, HH1
Chan, SO1
Zhang, HY1
Karimi, S1
Arabi, A1
Shahraki, T1
Safi, S1
Zhao, Y1
Li, X2
Li, S1
Dong, M1
Yu, H1
Zhang, M1
Chen, W1
Li, P1
Yu, Q1
Liu, X1
Gao, Z1
Wang, X1
Yang, W1
Zhu, Y1
Zhang, S1
Jiang, M1
Hu, J1
Zhang, HH1
Pei, Y1
Shu, Y1
Deng, B1
Liu, Y2
Huang, JX1
Liao, YF1
Li, YM1
Xia, Q1
Zhang, SH1
Yang, SM1
Zhu, XL1
Su, S1
Hu, AP1
Zhu, J1
Li, DM1
Prasanchaimontri, P1
Monga, M1
Lee, WL1
Wang, PH1
Chen, D1
Sun, X1
Zhao, X1
Hou, L1
Chen, Q1
Li, Q1
Zhao, M1
Hu, Y2
Chan, Z1
Li, C2
She, X1
Gu, C1
Wang, Y1
Zhou, C1
Zhao, S1
Zheng, Z2
Chen, H1
Kuwata, H1
Okamura, S1
Hayashino, Y1
Tsujii, S1
Ishii, H1
Vinuthinee-Naidu, MN1
Zunaina, E1
Azreen-Redzal, A1
Nyi-Nyi, N1
Cui, J1
Ren, JP1
Chen, DN1
Xin, Z1
Yuan, MX1
Xu, J1
You, QS1
Yang, JK1
Zhu, DD1
Wang, YZ1
Zou, C1
She, XP1
Ren, Y1
Gao, L1
Guo, X1
Huo, X1
Lu, J1
Li, J2
Ji, L1
Yang, X1
Thounaojam, MC1
Montemari, A1
Powell, FL1
Malla, P1
Gutsaeva, DR1
Bachettoni, A1
Ripandelli, G1
Repossi, A1
Tawfik, A1
Martin, PM1
Facchiano, F1
Bartoli, M1
Dziuba, J1
Alperin, P1
Racketa, J1
Iloeje, U1
Goswami, D1
Hardy, E1
Perlstein, I1
Grossman, HL1
Cohen, M1
Lee, JJ1
Yang, IH1
Kuo, HK1
Chung, MS1
Chen, YJ2
Chen, CH1
Liu, RT1
Li, LX1
Lu, JX1
Shuai, HP1
Xia, HF1
Zhang, R1
Wang, JW1
Chen, MY1
Li, TT1
Bao, YQ1
Jia, WP1
Liang, CC1
Lin, PC1
Lee, MY1
Chen, SC1
Shin, SJ1
Hsiao, PJ1
Lin, KD1
Hsu, WH1
Anan, F1
Masaki, T1
Ito, Y1
Eto, T1
Umeno, Y1
Eshima, N1
Saikawa, T1
Yoshimatsu, H1
Krizova, L1
Kalousova, M1
Kubena, A1
Benakova, H1
Zima, T1
Kovarik, Z1
Kalvoda, J1
Kalvodova, B1
Magri, CJ1
Calleja, N1
Buhagiar, G1
Fava, S1
Vassallo, J1
Liu, Q1
Cheng, R1
Chen, Y1
Lee, K1
Yi, J1
Liu, Z1
Ma, JX1
LAMAR, CP1
Huang, EJ1
Kuo, WW1
Chen, TH1
Chang, MH1
Lu, MC1
Tzang, BS1
Hsu, HH1
Huang, CY1
Lee, SD1
Mohora, M1
Vîrgolici, B1
Coman, A1
Muscurel, C1
Găman, L1
Gruia, V1
Greabu, M1
Yanko, L1
Goldbourt, U1
Michaelson, IC1
Shapiro, A1
Yaari, S1
Feldman, T1
Weitzman, S1
Biedner, B1
Elbagir, MN1
Eltom, MA1
Mahadi, EO1
Berne, C1
Nishimura, M1
Nakano, K1
Ushiyama, M1
Nanbu, A1
Ohtsuka, K1
Takahashi, H1
Yoshimura, M1
Bo, S1
Cavallo-Perin, P1
Gentile, L1
Repetti, E1
Pagano, G1
Peng, Z1
Wang, C1
Gao, Q1
Wang, Z1
Zhang, G1
Zhang, J1
Peng, J1
Jones, JJ1
Watkins, PJ1
Owyong, LY1
Loh, PP1
Kutty, MK1
Jogie, B1
Algan, B1
Leyder, C1
Marchal, H1
Geoffroy, D1
Marquis, A1
Müller, G1
Lantzsch, W1
Schubert, J1
Müller-Jensen, A1
Eickhoff, W1
Hellner, KA1
Olukoga, AO1
Erasmus, RT1
Akinlade, KS1
Okesina, AB1
Alanamu, AA1
Abu, EA1
Hanna, AK1
Roy, M1
Zinman, B1
McCulloch, JC1
Mortimer, C1
Falk, JA1
Chipman, M1
Gordon, AS1
Marliss, EB1
Darrelmann, O1
Kreissig, I1
Richard, G1

Reviews

1 review available for uric acid and Diabetic Retinopathy

ArticleYear
CHELATION THERAPY OF OCCLUSIVE ARTERIOSCLEROSIS IN DIABETIC PATIENTS.
    Angiology, 1964, Volume: 15

    Topics: Aged; Arteriosclerosis; Blood Urea Nitrogen; Chelation Therapy; Dermatitis; Diabetes Mellitus; Diabe

1964

Other Studies

42 other studies available for uric acid and Diabetic Retinopathy

ArticleYear
Transthyretin and retinol-binding protein as discriminators of diabetic retinopathy in type 1 diabetes mellitus.
    International ophthalmology, 2022, Volume: 42, Issue:4

    Topics: Apolipoproteins B; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Homocysteine; Humans; Prealbumin

2022
ELEVATED LEVEL OF URIC ACID, BUT NOT GLUCOSE, IN AQUEOUS HUMOR AS A RISK FACTOR FOR DIABETIC MACULAR EDEMA IN PATIENTS WITH TYPE 2 DIABETES.
    Retina (Philadelphia, Pa.), 2022, 06-01, Volume: 42, Issue:6

    Topics: Aqueous Humor; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Glucose; Humans; Macular Edema; Risk

2022
Association of White Blood Cell Counts, Leukocyte Ratios, and Serum Uric Acid with Clinical Outcome of Intravitreal Bevacizumab in Diabetic Macular Edema.
    Korean journal of ophthalmology : KJO, 2022, Volume: 36, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Diabetes Mellitus; Diabetic

2022
Using Machine Learning Techniques to Develop Risk Prediction Models for the Risk of Incident Diabetic Retinopathy Among Patients With Type 2 Diabetes Mellitus: A Cohort Study.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Machine L

2022
Genomic DNA Methylation in Diabetic Chronic Complications in Patients With Type 2 Diabetes Mellitus.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Carotid Intima-Media Thickness; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Type 2; Diabetic Ne

2022
Association between brachial-ankle pulse wave velocity and microvascular complications in type 2 diabetes mellitus.
    BMC endocrine disorders, 2023, May-04, Volume: 23, Issue:1

    Topics: Ankle; Ankle Brachial Index; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diab

2023
Clinical Features and Microvascular Complications Risk Factors of Early-onset Type 2 Diabetes Mellitus.
    Current medical science, 2019, Volume: 39, Issue:5

    Topics: Adult; Age of Onset; Aged; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Diabetes Mel

2019
Serum uric acid is independently associated with diabetic nephropathy but not diabetic retinopathy in patients with type 2 diabetes mellitus.
    Journal of the Chinese Medical Association : JCMA, 2020, Volume: 83, Issue:4

    Topics: Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopat

2020
Predictive Factors for Kidney Stone Recurrence in Type 2 Diabetes Mellitus.
    Urology, 2020, Volume: 143

    Topics: Aged; Asymptomatic Diseases; Body Mass Index; Calcium Oxalate; Causality; Cohort Studies; Comorbidit

2020
Uric acid in diabetic nephropathy.
    Journal of the Chinese Medical Association : JCMA, 2020, Volume: 83, Issue:8

    Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy;

2020
Associations of serum uric acid and urinary albumin with the severity of diabetic retinopathy in individuals with type 2 diabetes.
    BMC ophthalmology, 2020, Nov-30, Volume: 20, Issue:1

    Topics: Albumins; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Retrospective Studies; Uric Acid

2020
Associations of serum uric acid level with diabetic retinopathy and albuminuria in patients with type 2 diabetes mellitus.
    The Journal of international medical research, 2020, Volume: 48, Issue:12

    Topics: Adult; Aged; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; F

2020
Higher Serum Uric Acid Levels Are Associated With an Increased Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes Patients.
    Investigative ophthalmology & visual science, 2021, 04-01, Volume: 62, Issue:4

    Topics: Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Follow

2021
Serum uric acid levels are associated with increased risk of newly developed diabetic retinopathy among Japanese male patients with type 2 diabetes: A prospective cohort study (diabetes distress and care registry at Tenri [DDCRT 13]).
    Diabetes/metabolism research and reviews, 2017, Volume: 33, Issue:7

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Humans; Japan; M

2017
Correlation of retinal nerve fibre layer and macular thickness with serum uric acid among type 2 diabetes mellitus.
    BMC ophthalmology, 2017, Jun-14, Volume: 17, Issue:1

    Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Follow-Up S

2017
Prevalence and associated factors of diabetic retinopathy in Beijing, China: a cross-sectional study.
    BMJ open, 2017, Aug-30, Volume: 7, Issue:8

    Topics: Adult; Age Distribution; Aged; Blood Glucose; Blood Pressure; Body Mass Index; China; Cross-Sectiona

2017
The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway.
    Biochemical and biophysical research communications, 2018, 09-05, Volume: 503, Issue:2

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells;

2018
Interactive effect of serum uric acid and total bilirubin for micro-vascular disease of type 2 diabetes in China.
    Journal of diabetes and its complications, 2018, Volume: 32, Issue:11

    Topics: Aged; Bilirubin; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; D

2018
Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy.
    Diabetes, 2019, Volume: 68, Issue:5

    Topics: Allopurinol; Animals; Benzbromarone; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans;

2019
Modeling effects of SGLT-2 inhibitor dapagliflozin treatment versus standard diabetes therapy on cardiovascular and microvascular outcomes.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:7

    Topics: Amputation, Surgical; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Weight; Cardiovascul

2014
Serum uric acid concentration is associated with worsening in severity of diabetic retinopathy among type 2 diabetic patients in Taiwan--a 3-year prospective study.
    Diabetes research and clinical practice, 2014, Volume: 106, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Dise

2014
Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes.
    Atherosclerosis, 2015, Volume: 242, Issue:1

    Topics: Aged; Alcohol Drinking; Biomarkers; China; Comorbidity; Constriction, Pathologic; Cross-Sectional St

2015
Association of Serum Uric Acid Concentration with Diabetic Retinopathy and Albuminuria in Taiwanese Patients with Type 2 Diabetes Mellitus.
    International journal of molecular sciences, 2016, Aug-02, Volume: 17, Issue:8

    Topics: Aged; Albuminuria; Creatinine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Logi

2016
Diabetic retinopathy is associated with visceral fat accumulation in Japanese type 2 diabetes mellitus patients.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:3

    Topics: Adiposity; Aged; Anthropometry; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Di

2010
Increased uric acid and glucose concentrations in vitreous and serum of patients with diabetic macular oedema.
    Ophthalmic research, 2011, Volume: 46, Issue:2

    Topics: Aged; Blood Glucose; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Female; Glycated He

2011
Factors associated with diabetic nephropathy in subjects with proliferative retinopathy.
    International urology and nephrology, 2012, Volume: 44, Issue:1

    Topics: Aged; Albuminuria; Blood Pressure; Blood Sedimentation; C-Reactive Protein; Circadian Rhythm; Diabet

2012
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy.
    Antioxidants & redox signaling, 2013, Apr-01, Volume: 18, Issue:10

    Topics: Aldehydes; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme

2013
Homocysteine and other biochemical parameters in Type 2 diabetes mellitus with different diabetic duration or diabetic retinopathy.
    Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 366, Issue:1-2

    Topics: Aged; Albuminuria; Bilirubin; Biomarkers; Blood Glucose; C-Reactive Protein; Chromatography, High Pr

2006
Diabetic foot patients with and without retinopathy and plasma oxidative stress.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2007, Volume: 45, Issue:1

    Topics: Acute-Phase Proteins; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Foot; Di

2007
Prevalence and 15-year incidence of retinopathy and associated characteristics in middle-aged and elderly diabetic men.
    The British journal of ophthalmology, 1983, Volume: 67, Issue:11

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetic Retinopathy; Humans; Israel; Male; Middle Ag

1983
[Retinopathy and serum uric acid in diabetics].
    Harefuah, 1995, Jun-01, Volume: 128, Issue:11

    Topics: Body Mass Index; Diabetes Mellitus; Diabetic Retinopathy; Humans; Male; Regression Analysis; Sex Fac

1995
Pattern of long-term complications in Sudanese insulin-treated diabetic patients.
    Diabetes research and clinical practice, 1995, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disord

1995
Increased serum concentrations of human hepatocyte growth factor in proliferative diabetic retinopathy.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Blood Pressure; Diabetic Retinopathy; Fem

1998
Relationship of residual beta-cell function, metabolic control and chronic complications in type 2 diabetes mellitus.
    Acta diabetologica, 2000, Volume: 37, Issue:3

    Topics: Aged; Albuminuria; Body Mass Index; C-Reactive Protein; Cholesterol, HDL; Cohort Studies; Diabetes M

2000
[Simultaneous determination of creatinine, pseudouridine and uric acid in serum and urine by high performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 1998, Volume: 16, Issue:2

    Topics: Chromatography, High Pressure Liquid; Creatinine; Diabetic Nephropathies; Diabetic Retinopathy; Huma

1998
Diabetes and its vascular complications in Malaysia.
    Tropical and geographical medicine, 1978, Volume: 30, Issue:4

    Topics: Adult; Aged; Blood Glucose; Cerebrovascular Disorders; Cholesterol; Coronary Disease; Diabetes Melli

1978
[Etiology of retinal venous thromboses].
    Bulletin de la Societe belge d'ophtalmologie, 1976, Mar-07, Volume: 172, Issue:2

    Topics: Adult; Arteriosclerosis; Diabetic Retinopathy; Female; Humans; Hypertension; Retinal Vein; Thrombosi

1976
[Glycoproteins in diabetes mellitus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Jun-01, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Aged; alpha 1-Antitrypsin; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Typ

1975
[Clinical-neurological and electromyographical studies of inpatients isolated with selective pigmentary retinopathy].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1975, Volume: 170, Issue:6

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diabetes Mellitus; Diabetic Retinopathy; Electroen

1975
Plasma urate in diabetes: relationship to glycaemia, glucose disposal, microvascular complications and the variations following oral glucose.
    Diabetes research and clinical practice, 1991, Volume: 14, Issue:2

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2;

1991
An evaluation of factors associated with proliferative diabetic retinopathy.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:2

    Topics: Adult; Angina Pectoris; Blood Coagulation; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neurop

1985
[Bilateral retinal vein occlusions and general risk factors].
    Klinische Monatsblatter fur Augenheilkunde, 1985, Volume: 186, Issue:1

    Topics: Aged; Constriction, Pathologic; Diabetic Retinopathy; Female; Heart Failure; Humans; Hypercholestero

1985